Year |
Citation |
Score |
2022 |
Watts E, Thyer R, Ellington AD, Brodbelt JS. Integrated Top-Down and Bottom-Up Mass Spectrometry for Characterization of Diselenide Bridging Patterns of Synthetic Selenoproteins. Analytical Chemistry. PMID 35930618 DOI: 10.1021/acs.analchem.2c01433 |
0.455 |
|
2022 |
d'Oelsnitz S, Kim W, Burkholder NT, Javanmardi K, Thyer R, Zhang Y, Alper HS, Ellington AD. Using fungible biosensors to evolve improved alkaloid biosyntheses. Nature Chemical Biology. PMID 35799063 DOI: 10.1038/s41589-022-01072-w |
0.427 |
|
2021 |
Thyer R, d'Oelsnitz S, Blevins MS, Klein DR, Brodbelt JS, Ellington AD. Directed evolution of an improved aminoacyl-tRNA synthetase for incorporation of L-3,4-dihydroxyphenylalanine (L-DOPA). Angewandte Chemie (International Ed. in English). PMID 33871147 DOI: 10.1002/anie.202100579 |
0.391 |
|
2020 |
Shroff R, Cole AW, Diaz DJ, Morrow BR, Donnell I, Annapareddy A, Gollihar J, Ellington AD, Thyer R. Discovery of Novel Gain-of-Function Mutations Guided by Structure-Based Deep Learning. Acs Synthetic Biology. PMID 33064458 DOI: 10.1021/acssynbio.0c00345 |
0.415 |
|
2018 |
Thyer R, Ellington AD. The role of tRNA in Establishing New Genetic Codes. Biochemistry. PMID 30387992 DOI: 10.1021/Acs.Biochem.8B00834 |
0.603 |
|
2018 |
Thyer R, Shroff R, Klein DR, d'Oelsnitz S, Cotham VC, Byrom M, Brodbelt JS, Ellington AD. Custom selenoprotein production enabled by laboratory evolution of recoded bacterial strains. Nature Biotechnology. PMID 29863724 DOI: 10.1038/Nbt.4154 |
0.504 |
|
2017 |
Cammarata M, Thyer R, Lombardo M, Anderson A, Wright D, Ellington A, Brodbelt JS. Characterization of trimethoprim resistant dihydrofolate reductase mutants by mass spectrometry and inhibition by propargyl-linked antifolates. Chemical Science. 8: 4062-4072. PMID 29967675 DOI: 10.1039/C6Sc05235E |
0.457 |
|
2016 |
Cammarata MB, Thyer R, Rosenberg J, Ellington A, Brodbelt JS. Correction to "Structural Characterization of Dihydrofolate Reductase Complexes by Top-Down Ultraviolet Photodissociation Mass Spectrometry". Journal of the American Chemical Society. 138: 3252. PMID 26919090 DOI: 10.1021/Jacs.6B01611 |
0.483 |
|
2016 |
Tack DS, Ellefson JW, Thyer R, Wang B, Gollihar J, Forster MT, Ellington AD. Addicting diverse bacteria to a noncanonical amino acid. Nature Chemical Biology. PMID 26780407 DOI: 10.1038/Nchembio.2002 |
0.61 |
|
2015 |
Cammarata MB, Thyer R, Rosenberg J, Ellington A, Brodbelt JS. Structural Characterization of Dihydrofolate Reductase Complexes by Top-Down Ultraviolet Photodissociation Mass Spectrometry. Journal of the American Chemical Society. 137: 9128-35. PMID 26125523 DOI: 10.1021/Jacs.5B04628 |
0.45 |
|
2015 |
Thyer R, Robotham SA, Brodbelt JS, Ellington AD. Evolving tRNA(Sec) for efficient canonical incorporation of selenocysteine. Journal of the American Chemical Society. 137: 46-9. PMID 25521771 DOI: 10.1021/Ja510695G |
0.524 |
|
2014 |
Thyer R, Ellefson J. Synthetic biology: New letters for life's alphabet. Nature. 509: 291-2. PMID 24805244 DOI: 10.1038/Nature13335 |
0.62 |
|
2013 |
Thyer R, Filipovska A, Rackham O. Engineered rRNA enhances the efficiency of selenocysteine incorporation during translation. Journal of the American Chemical Society. 135: 2-5. PMID 23256865 DOI: 10.1021/Ja3069177 |
0.356 |
|
2011 |
Rackham O, Shearwood AM, Thyer R, McNamara E, Davies SM, Callus BA, Miranda-Vizuete A, Berners-Price SJ, Cheng Q, Arnér ES, Filipovska A. Substrate and inhibitor specificities differ between human cytosolic and mitochondrial thioredoxin reductases: Implications for development of specific inhibitors. Free Radical Biology & Medicine. 50: 689-99. PMID 21172426 DOI: 10.1016/J.Freeradbiomed.2010.12.015 |
0.302 |
|
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