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Alexander Heckel - Publications

Affiliations: 
Goethe University, Frankfurt am Main 
Area:
optochemical biology
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52 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Wohlrábová L, Sahlbach M, Heckel A, Slanina T. BODIPY phototether enables oligonucleotide cyclization and subsequent deprotection by tissue-transparent red light. Chemical Communications (Cambridge, England). PMID 38563214 DOI: 10.1039/d4cc00272e  0.619
2019 Müller P, Seyfried P, Frühauf A, Heckel A. Phosphodiester photo-tethers for the (multi-)cyclic conformational caging of oligonucleotides. Methods in Enzymology. 624: 89-111. PMID 31370937 DOI: 10.1016/bs.mie.2019.04.019  0.316
2018 Seyfried P, Heinz M, Pintér G, Klötzner DP, Becker Y, Bolte M, Jonker H, Stelzl L, Hummer G, Schwalbe H, Heckel A. Optimal destabilization of DNA double strands by single-nucleobase caging. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 30199112 DOI: 10.1002/Chem.201804040  0.339
2018 Reinfelds M, von Cosel J, Falahati K, Hamerla C, Slanina T, Heckel A, Burghardt I. A new photocage derived from fluorene. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 29889321 DOI: 10.1002/Chem.201802390  0.615
2018 Grebenovsky N, Goldau T, Bolte M, Heckel A. Light Regulation of DNA Minicircle Dimerization by Utilizing Azobenzene C-Nucleosides. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 29418024 DOI: 10.1002/chem.201706003  0.353
2017 Weyel XMM, Fichte MAH, Heckel A. A Two-Photon-Photocleavable Linker for Triggering Light-Induced Strand Breaks in Oligonucleotides. Acs Chemical Biology. PMID 28678467 DOI: 10.1021/acschembio.7b00367  0.324
2017 Meyer A, Slanina T, Heckel A, König B. Metal ion coupled consecutive photoinduced electron transfer generates strong reduction potentials from visible light. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 28429580 DOI: 10.1002/Chem.201701665  0.621
2016 Seyfried P, Eiden L, Grebenovsky N, Mayer G, Heckel A. Photo-Tethers for the (Multi-)Cyclic, Conformational Caging of Long Oligonucleotides. Angewandte Chemie (International Ed. in English). PMID 27897376 DOI: 10.1002/Anie.201610025  0.43
2015 Goldau T, Murayama K, Brieke C, Asanuma H, Heckel A. Azobenzene C-Nucleosides for Photocontrolled Hybridization of DNA at Room Temperature. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 26489532 DOI: 10.1002/chem.201503303  0.341
2015 Slanina T, Šebej P, Heckel A, Givens RS, Klán P. Caged Fluoride: Photochemistry and Applications of 4-Hydroxyphenacyl Fluoride. Organic Letters. 17: 4814-7. PMID 26378924 DOI: 10.1021/Acs.Orglett.5B02374  0.68
2015 Mondal P, Biswas M, Goldau T, Heckel A, Burghardt I. In Search of an Efficient Photoswitch for Functional RNA: Design Principles from a Microscopic Analysis of Azobenzene-linker-RNA Dynamics with Different Linkers. The Journal of Physical Chemistry. B. 119: 11275-86. PMID 26125118 DOI: 10.1021/Acs.Jpcb.5B03118  0.698
2015 Goldau T, Murayama K, Brieke C, Steinwand S, Mondal P, Biswas M, Burghardt I, Wachtveitl J, Asanuma H, Heckel A. Reversible photoswitching of RNA hybridization at room temperature with an azobenzene C-nucleoside. Chemistry (Weinheim An Der Bergstrasse, Germany). 21: 2845-54. PMID 25537843 DOI: 10.1002/Chem.201405840  0.684
2014 Steinert HS, Schäfer F, Jonker HR, Heckel A, Schwalbe H. Influence of the absolute configuration of npe-caged cytosine on DNA single base pair stability. Angewandte Chemie (International Ed. in English). 53: 1072-5. PMID 24339185 DOI: 10.1002/Anie.201307852  0.321
2013 Brieke C, Heckel A. Spiropyran photoswitches in the context of DNA: synthesis and photochromic properties. Chemistry (Weinheim An Der Bergstrasse, Germany). 19: 15726-34. PMID 24115210 DOI: 10.1002/chem.201302640  0.336
2012 Brieke C, Rohrbach F, Gottschalk A, Mayer G, Heckel A. Light-controlled tools. Angewandte Chemie (International Ed. in English). 51: 8446-76. PMID 22829531 DOI: 10.1002/Anie.201202134  0.31
2012 Joshi KB, Vlachos A, Mikat V, Deller T, Heckel A. Light-activatable molecular beacons with a caged loop sequence. Chemical Communications (Cambridge, England). 48: 2746-8. PMID 22159276 DOI: 10.1039/c2cc16654b  0.72
2012 Pinto A, Lennarz S, Rodrigues-Correia A, Heckel A, O'Sullivan CK, Mayer G. Functional detection of proteins by caged aptamers. Acs Chemical Biology. 7: 360-6. PMID 22070344 DOI: 10.1021/Cb2003835  0.349
2011 Menge C, Heckel A. Coumarin-caged dG for improved wavelength-selective uncaging of DNA. Organic Letters. 13: 4620-3. PMID 21834506 DOI: 10.1021/Ol201842X  0.328
2011 Schmidt TL, Koeppel MB, Thevarpadam J, Gonçalves DP, Heckel A. A light trigger for DNA nanotechnology. Small (Weinheim An Der Bergstrasse, Germany). 7: 2163-7. PMID 21638782 DOI: 10.1002/Smll.201100182  0.404
2011 Friedrich F, Heckel A. Photon cascade with clip-on fluorophores. Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry. 12: 2073-5. PMID 21567707 DOI: 10.1002/Cphc.201100295  0.388
2011 Schmidt TL, Heckel A. Construction of a structurally defined double-stranded DNA catenane. Nano Letters. 11: 1739-42. PMID 21410245 DOI: 10.1021/Nl200303M  0.481
2011 Schäfer F, Joshi KB, Fichte MAH, MacK T, Wachtveitl J, Heckel A. Wavelength-selective uncaging of da and dC residues Organic Letters. 13: 1450-1453. PMID 21341754 DOI: 10.1021/Ol200141V  0.699
2011 Rodrigues-Correia A, Koeppel MB, Schäfer F, Joshi KB, MacK T, Heckel A. Comparison of the duplex-destabilizing effects of nucleobase-caged oligonucleotides Analytical and Bioanalytical Chemistry. 399: 441-447. PMID 20953770 DOI: 10.1007/S00216-010-4274-7  0.401
2010 Gonçalves DP, Schmidt TL, Koeppel MB, Heckel A. DNA minicircles connected via G-quadruplex interaction modules. Small (Weinheim An Der Bergstrasse, Germany). 6: 1347-52. PMID 20486229 DOI: 10.1002/Smll.201000318  0.4
2010 Ackermann D, Rasched G, Verma S, Schmidt TL, Heckel A, Famulok M. Assembly of dsDNA nanocircles into dimeric and oligomeric aggregates. Chemical Communications (Cambridge, England). 46: 4154-6. PMID 20473448 DOI: 10.1039/C0Cc00390E  0.517
2010 Ackermann D, Schmidt TL, Hannam JS, Purohit CS, Heckel A, Famulok M. A double-stranded DNA rotaxane. Nature Nanotechnology. 5: 436-42. PMID 20400967 DOI: 10.1038/Nnano.2010.65  0.455
2010 Wurm JP, Meyer B, Bahr U, Held M, Frolow O, Kötter P, Engels JW, Heckel A, Karas M, Entian KD, Wöhnert J. The ribosome assembly factor Nep1 responsible for Bowen-Conradi syndrome is a pseudouridine-N1-specific methyltransferase. Nucleic Acids Research. 38: 2387-98. PMID 20047967 DOI: 10.1093/Nar/Gkp1189  0.355
2009 Schmidt TL, Heckel A. Pyrrole/imidazole-polyamide anchors for DNA tertiary interactions. Small (Weinheim An Der Bergstrasse, Germany). 5: 1517-20. PMID 19360724 DOI: 10.1002/smll.200900147  0.304
2008 Heckel A, Famulok M. Building objects from nucleic acids for a nanometer world. Biochimie. 90: 1096-107. PMID 18316041 DOI: 10.1016/J.Biochi.2008.02.004  0.363
2008 Nandi CK, Parui PP, Schmidt TL, Heckel A, Brutschy B. Binding of hairpin polyamides to DNA studied by fluorescence correlation spectroscopy for DNA nanoarchitectures. Analytical and Bioanalytical Chemistry. 390: 1595-603. PMID 18224303 DOI: 10.1007/S00216-008-1852-Z  0.724
2008 Rasched G, Ackermann D, Schmidt TL, Broekmann P, Heckel A, Famulok M. DNA minicircles with gaps for versatile functionalization. Angewandte Chemie (International Ed. in English). 47: 967-70. PMID 18058876 DOI: 10.1002/Anie.200704004  0.495
2008 Rasched G, Ackermann D, Schmidt T, Broekmann P, Heckel A, Famulok M, Mayer G, Kuhn N. Cover Picture: DNA Minicircles with Gaps for Versatile Functionalization / Construction of DNA Architectures with RNA Hairpins (Angew. Chem. Int. Ed. 5/2008) Angewandte Chemie International Edition. 47: 803-803. DOI: 10.1002/Anie.200890008  0.427
2008 Rasched G, Ackermann D, Schmidt T, Broekmann P, Heckel A, Famulok M, Mayer G, Kuhn N. Titelbild: DNA-Ringe mit Einzelstrangdomänen zur vielseitigen Funktionalisierung / Aufbau von DNA-Architekturen mit RNA-Haarnadelschleifen (Angew. Chem. 5/2008) Angewandte Chemie. 120: 815-815. DOI: 10.1002/Ange.200890009  0.431
2008 Rasched G, Ackermann D, Schmidt T, Broekmann P, Heckel A, Famulok M. DNA-Ringe mit Einzelstrangdomänen zur vielseitigen Funktionalisierung Angewandte Chemie. 120: 981-984. DOI: 10.1002/Ange.200704004  0.398
2007 Hsu CF, Phillips JW, Trauger JW, Farkas ME, Belitsky JM, Heckel A, Olenyuk BZ, Puckett JW, Wang CC, Dervan PB. Completion of a Programmable DNA-Binding Small Molecule Library. Tetrahedron. 63: 6146-6151. PMID 18596841 DOI: 10.1016/J.Tet.2007.03.041  0.697
2007 Heckel A. Nucleobase-caged phosphoramidites for oligonucleotide synthesis. Current Protocols in Nucleic Acid Chemistry. Unit 1.17. PMID 18428965 DOI: 10.1002/0471142700.Nc0117S29  0.317
2007 Mikat V, Heckel A. Light-dependent RNA interference with nucleobase-caged siRNAs. Rna (New York, N.Y.). 13: 2341-7. PMID 17951332 DOI: 10.1261/Rna.753407  0.314
2007 Schmidt TL, Nandi CK, Rasched G, Parui PP, Brutschy B, Famulok M, Heckel A. Polyamide struts for DNA architectures. Angewandte Chemie (International Ed. in English). 46: 4382-4. PMID 17458850 DOI: 10.1002/Anie.200700469  0.733
2007 Morgner N, Barth HD, Schmidt TL, Heckel A, Scheffer U, Göbel M, Fucini P, Brutschy B. Detecting specific ligand binding to nucleic acids: A test for ultrasoft laser mass spectrometry Zeitschrift Fur Physikalische Chemie. 221: 689-704. DOI: 10.1524/Zpch.2007.221.5.689  0.386
2007 Schmidt T, Nandi C, Rasched G, Parui P, Brutschy B, Famulok M, Heckel A. Polyamid-Stützen für DNA-Architekturen Angewandte Chemie. 119: 4460-4462. DOI: 10.1002/Ange.200700469  0.683
2005 Mayer G, Kröck L, Mikat V, Engeser M, Heckel A. Light-induced formation of G-quadruplex DNA secondary structures. Chembiochem : a European Journal of Chemical Biology. 6: 1966-70. PMID 16178038 DOI: 10.1002/Cbic.200500198  0.378
2005 Heckel A, Mayer G. Light regulation of aptamer activity: an anti-thrombin aptamer with caged thymidine nucleobases. Journal of the American Chemical Society. 127: 822-3. PMID 15656605 DOI: 10.1021/Ja043285E  0.317
2005 Mayer G, Kröck L, Mikat V, Engeser M, Heckel A. Cover Picture: Light-Induced Formation of G-Quadruplex DNA Secondary Structures (ChemBioChem 11/2005) Chembiochem. 6: 1913-1913. DOI: 10.1002/Cbic.200590036  0.379
2004 Heckel A. A new DNA analogue with expanded size and scope. Chembiochem : a European Journal of Chemical Biology. 5: 765-7. PMID 15174157 DOI: 10.1002/Cbic.200400001  0.387
2004 Edelson BS, Best TP, Olenyuk B, Nickols NG, Doss RM, Foister S, Heckel A, Dervan PB. Influence of structural variation on nuclear localization of DNA-binding polyamide-fluorophore conjugates. Nucleic Acids Research. 32: 2802-18. PMID 15155849 DOI: 10.1093/Nar/Gkh609  0.625
2003 Heckel A, Dervan PB. U-pin polyamide motif for recognition of the DNA minor groove. Chemistry (Weinheim An Der Bergstrasse, Germany). 9: 3353-66. PMID 12866079 DOI: 10.1002/Chem.200304784  0.615
2003 Heckel A, Dervan PB. Cover Picture: U-Pin Polyamide Motif for Recognition of the DNA Minor Groove (Chem. Eur. J. 14/2003) Chemistry - a European Journal. 9: 3173-3173. DOI: 10.1002/Chem.200390233  0.584
2002 Heckel A, Seebach D. Preparation and characterization of TADDOLs immobilized on hydrophobic controlled-pore-glass silica gel and their use in enantioselective heterogeneous catalysis. Chemistry (Weinheim An Der Bergstrasse, Germany). 8: 559-72. PMID 11855704 DOI: 10.1002/1521-3765(20020201)8:3<559::Aid-Chem559>3.0.Co;2-1  0.437
2002 Heckel A, Seebach D. Enantioselective Heterogeneous Epoxidation and Hetero-Diels-Alder Reaction with Mn- and Cr-salen Complexes Immobilized on Silica Gel by Radical Grafting Helvetica Chimica Acta. 85: 913. DOI: 10.1002/1522-2675(200203)85:3<913::Aid-Hlca913>3.0.Co;2-U  0.408
2001 Seebach D, Beck AK, Heckel A. TADDOLs, Their Derivatives, and TADDOL Analogues: Versatile Chiral Auxiliaries. Angewandte Chemie (International Ed. in English). 40: 92-138. PMID 11169693 DOI: 10.1002/1521-3773(20010105)40:1<92::Aid-Anie92>3.0.Co;2-K  0.429
2001 Seebach D, Beck AK, Heckel A. TADDOLe, ihre Derivate und Analoga – vielseitige chirale Hilfsstoffe Angewandte Chemie. 113: 96-142. DOI: 10.1002/1521-3757(20010105)113:1<96::Aid-Ange96>3.0.Co;2-B  0.358
2000 Heckel A, Seebach D. Immobilization of TADDOL with a High Degree of Loading on Porous Silica Gel and First Applications in Enantioselective Catalysis. Angewandte Chemie (International Ed. in English). 39: 163-165. PMID 10649361 DOI: 10.1002/(Sici)1521-3773(20000103)39:1<163::Aid-Anie163>3.0.Co;2-J  0.421
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