| Year |
Citation |
Score |
| 2021 |
An J, Intano J, Richard A, Kim T, Gascón JA, Howell AR. Easily accessible non-aromatic heterocycles with handles: 4-bromo-2,3-dihydrofurans from 1,2-dibromohomoallylic alcohols. Chemical Science. 12: 10347-10353. PMID 34377420 DOI: 10.1039/d1sc01013a |
0.758 |
|
| 2020 |
Saavedra-Avila NA, Keshipeddy S, Guberman-Pfeffer MJ, Pérez-Gallegos A, Saini NK, Schäfer C, Carreño LJ, Gascón JA, Porcelli SA, Howell AR. Amide-Linked C4″-Saccharide Modification of KRN7000 Provides Potent Stimulation of Human Invariant NKT Cells and Anti-Tumor Immunity in a Humanized Mouse Model. Acs Chemical Biology. PMID 33296161 DOI: 10.1021/acschembio.0c00707 |
0.741 |
|
| 2018 |
Chandra S, Gray J, Kiosses WB, Khurana A, Hitomi K, Crosby CM, Chawla A, Fu Z, Zhao M, Veerapen N, Richardson SK, Porcelli SA, Besra G, Howell AR, Sharma S, et al. Mrp1 is involved in lipid presentation and iNKT cell activation by Streptococcus pneumoniae. Nature Communications. 9: 4279. PMID 30323255 DOI: 10.1038/S41467-018-06646-8 |
0.313 |
|
| 2018 |
Chennamadhavuni D, Saavedra-Avila NA, Carreño LJ, Guberman-Pfeffer MJ, Arora P, Yongqing T, Pryce R, Koay HF, Godfrey DI, Keshipeddy S, Richardson SK, Sundararaj S, Lo JH, Wen X, Gascón JA, ... ... Howell AR, et al. Dual Modifications of α-Galactosylceramide Synergize to Promote Activation of Human Invariant Natural Killer T Cells and Stimulate Anti-tumor Immunity. Cell Chemical Biology. 25: 925. PMID 30028975 DOI: 10.1016/J.Chembiol.2018.06.008 |
0.736 |
|
| 2018 |
Chennamadhavuni D, Saavedra-Avila NA, Carreño LJ, Guberman-Pfeffer MJ, Arora P, Yongqing T, Koay HF, Godfrey DI, Keshipeddy S, Richardson SK, Sundararaj S, Lo JH, Wen X, Gascón JA, Yuan W, ... ... Howell AR, et al. Dual Modifications of α-Galactosylceramide Synergize to Promote Activation of Human Invariant Natural Killer T Cells and Stimulate Anti-tumor Immunity. Cell Chemical Biology. PMID 29576533 DOI: 10.1016/J.Chembiol.2018.02.009 |
0.749 |
|
| 2018 |
Zhang Y, Senanayake C, Lao K, Sieber J, Xu Y, Wu L, Wang X, Desrosiers J, Lee H, Haddad N, Han Z, Yee N, Song J, Howell A. Modular Dihydrobenzoazaphosphole Ligands for Suzuki–Miyaura Cross-Coupling Synthesis. 50: 4429-4434. DOI: 10.1055/S-0037-1610158 |
0.774 |
|
| 2017 |
Malapit CA, Luvaga IK, Caldwell DR, Schipper NK, Howell AR. Rh-Catalyzed Conjugate Addition of Aryl and Alkenyl Boronic Acids to α-Methylene-β-lactones: Stereoselective Synthesis of trans-3,4-Disubstituted β-Lactones. Organic Letters. PMID 28809569 DOI: 10.1021/Acs.Orglett.7B01994 |
0.738 |
|
| 2017 |
Li S, Diego-Limpin PA, Bajrami B, Keshipeddy S, Lam YW, Deng B, Farrokhi V, McShane AJ, Nemati R, Howell AR, Yao X. Scaling Proteome-wide Reactions of Activity-Based Probes. Analytical Chemistry. PMID 28570047 DOI: 10.1021/Acs.Analchem.7B01184 |
0.729 |
|
| 2017 |
Malapit CA, Caldwell DR, Luvaga IK, Reeves JT, Volchkov I, Gonnella NC, Han ZS, Busacca CA, Howell AR, Senanayake CH. Rhodium-Catalyzed Addition of Aryl Boronic Acids to 2,2-Disubstituted Malononitriles. Angewandte Chemie (International Ed. in English). PMID 28493607 DOI: 10.1002/Anie.201703471 |
0.791 |
|
| 2017 |
Betts RJ, Perkovic A, Mahapatra S, Bufalo AD, Camara K, Howell AR, Teissier SM, De Libero G, Mori L. Contact sensitizers trigger human CD1-autoreactive T-cell responses. European Journal of Immunology. PMID 28440548 DOI: 10.1002/Eji.201746939 |
0.312 |
|
| 2017 |
Malapit CA, Luvaga IK, Reeves JT, Volchkov I, Busacca CA, Howell AR, Senanayake CH. 1,4-Dicarbofunctionalization of 4-Fluoroaryl Grignard and Lithium Reagents with Disubstituted Malononitriles. The Journal of Organic Chemistry. PMID 28402664 DOI: 10.1021/Acs.Joc.7B00567 |
0.775 |
|
| 2017 |
Malapit CA, Caldwell DR, Sassu N, Milbin S, Howell AR. Pd-Catalyzed Acyl C-O Bond Activation for Selective Ring-Opening of α-Methylene-β-lactones with Amines. Organic Letters. PMID 28375015 DOI: 10.1021/Acs.Orglett.7B00494 |
0.727 |
|
| 2016 |
Le Nours J, Praveena T, Pellicci DG, Gherardin NA, Ross FJ, Lim RT, Besra GS, Keshipeddy S, Richardson SK, Howell AR, Gras S, Godfrey DI, Rossjohn J, Uldrich AP. Atypical natural killer T-cell receptor recognition of CD1d-lipid antigens. Nature Communications. 7: 10570. PMID 26875526 DOI: 10.1038/Ncomms10570 |
0.744 |
|
| 2015 |
Malapit CA, Reeves JT, Busacca CA, Howell AR, Senanayake CH. Rhodium-Catalyzed Transnitrilation of Aryl Boronic Acids with Dimethylmalononitrile. Angewandte Chemie (International Ed. in English). PMID 26483150 DOI: 10.1002/Anie.201508122 |
0.782 |
|
| 2015 |
Wingender G, Birkholz AM, Sag D, Farber E, Chitale S, Howell AR, Kronenberg M. Selective Conditions Are Required for the Induction of Invariant NKT Cell Hyporesponsiveness by Antigenic Stimulation. Journal of Immunology (Baltimore, Md. : 1950). 195: 3838-48. PMID 26355152 DOI: 10.4049/Jimmunol.1500203 |
0.786 |
|
| 2015 |
Birkholz AM, Howell AR, Kronenberg M. The alpha and omega of galactosylceramides in T cell immune function. The Journal of Biological Chemistry. 290: 20746. PMID 26297715 DOI: 10.1074/Jbc.A115.647057 |
0.369 |
|
| 2015 |
Malapit CA, Howell AR. Recent Applications of Oxetanes in the Synthesis of Heterocyclic Compounds. The Journal of Organic Chemistry. 80: 8489-95. PMID 26225624 DOI: 10.1021/Acs.Joc.5B01255 |
0.726 |
|
| 2015 |
Chennamadhavuni D, Howell AR. A Solvent-free Approach to Glycosyl Amides: Towards the Synthesis of α-N-Galactosyl Ceramides. Tetrahedron Letters. 56: 3583-3586. PMID 26028787 DOI: 10.1016/J.Tetlet.2015.02.133 |
0.361 |
|
| 2015 |
Birkholz A, Nem?ovi? M, Yu ED, Girardi E, Wang J, Khurana A, Pauwels N, Farber E, Chitale S, Franck RW, Tsuji M, Howell A, Van Calenbergh S, Kronenberg M, Zajonc DM. Lipid and Carbohydrate Modifications of α-Galactosylceramide Differently Influence Mouse and Human Type I Natural Killer T Cell Activation. The Journal of Biological Chemistry. 290: 17206-17. PMID 26018083 DOI: 10.1074/Jbc.M115.654814 |
0.788 |
|
| 2015 |
Malapit CA, Chitale SM, Thakur MS, Taboada R, Howell AR. Pt-catalyzed rearrangement of oxaspirohexanes to 3-methylenetetrahydrofurans: scope and mechanism. The Journal of Organic Chemistry. 80: 5196-209. PMID 25893894 DOI: 10.1021/Acs.Joc.5B00604 |
0.751 |
|
| 2015 |
Camara K, Kamat SS, Lasota CC, Cravatt BF, Howell AR. Combining cross-metathesis and activity-based protein profiling: new β-lactone motifs for targeting serine hydrolases. Bioorganic & Medicinal Chemistry Letters. 25: 317-21. PMID 25541002 DOI: 10.1016/J.Bmcl.2014.11.038 |
0.305 |
|
| 2015 |
Malapit CA, Visco MD, Reeves JT, Busacca CA, Howell AR, Senanayake CH. ChemInform Abstract: Nickel- or Cobalt-Catalyzed Cross-Coupling of Arylsulfonic Acid Salts with Grignard Reagents. Cheminform. 46: no-no. DOI: 10.1002/CHIN.201548061 |
0.699 |
|
| 2015 |
Malapit CA, Visco MD, Reeves JT, Busacca CA, Howell AR, Senanayake CH. Nickel- or Cobalt-Catalyzed Cross-Coupling of Arylsulfonic Acid Salts with Grignard Reagents Advanced Synthesis and Catalysis. 357: 2199-2204. DOI: 10.1002/Adsc.201500304 |
0.762 |
|
| 2014 |
Pellicci DG, Uldrich AP, Le Nours J, Ross F, Chabrol E, Eckle SB, de Boer R, Lim RT, McPherson K, Besra G, Howell AR, Moretta L, McCluskey J, Heemskerk MH, Gras S, et al. The molecular bases of δ/αβ T cell-mediated antigen recognition. The Journal of Experimental Medicine. 211: 2599-615. PMID 25452463 DOI: 10.1084/Jem.20141764 |
0.358 |
|
| 2014 |
Thakur MS, Khurana A, Kronenberg M, Howell AR. Synthesis of a 2"-deoxy-β-GalCer. Molecules (Basel, Switzerland). 19: 10090-102. PMID 25014535 DOI: 10.3390/Molecules190710090 |
0.671 |
|
| 2014 |
Pellicci DG, Uldrich AP, Nours JL, Ross F, Chabrol E, Eckle SBG, Boer Rd, Lim RT, McPherson K, Besra G, Howell AR, Moretta L, McCluskey J, Heemskerk MHM, Gras S, et al. The molecular bases of delta/alpha beta T cell-mediated antigen recognition Journal of Experimental Medicine. 211: 2599-2615. DOI: 10.2210/Pdb4Wnq/Pdb |
0.31 |
|
| 2014 |
Kona JR, King'Ondu CK, Howell AR, Suib SL. OMS-2 for aerobic, catalytic, one-pot alcohol oxidation-wittig reactions: Efficient access to α,β-unsaturated esters Chemcatchem. 6: 749-752. DOI: 10.1002/Cctc.201300942 |
0.325 |
|
| 2013 |
Farber E, Rudnitskaya A, Keshipeddy S, Lao KS, Gascón JA, Howell AR. Silicon acceleration of a tandem alkene isomerization/electrocyclic ring-opening of 2-methyleneoxetanes to α,β-unsaturated methylketones. The Journal of Organic Chemistry. 78: 11213-20. PMID 24111612 DOI: 10.1021/Jo4014645 |
0.769 |
|
| 2012 |
Wun KS, Ross F, Patel O, Besra GS, Porcelli SA, Richardson SK, Keshipeddy S, Howell AR, Godfrey DI, Rossjohn J. Human and mouse type I natural killer T cell antigen receptors exhibit different fine specificities for CD1d-antigen complex. The Journal of Biological Chemistry. 287: 39139-48. PMID 22995911 DOI: 10.1074/Jbc.M112.412320 |
0.734 |
|
| 2012 |
Keshipeddy S, MartÃnez I, Castillo BF, Morton MD, Howell AR. Toward a formal synthesis of laureatin: unexpected rearrangements involving cyclic ether nucleophiles. The Journal of Organic Chemistry. 77: 7883-90. PMID 22913294 DOI: 10.1021/Jo301048Z |
0.749 |
|
| 2011 |
Tyznik AJ, Farber E, Girardi E, Birkholz A, Li Y, Chitale S, So R, Arora P, Khurana A, Wang J, Porcelli SA, Zajonc DM, Kronenberg M, Howell AR. Glycolipids that elicit IFN-γ-biased responses from natural killer T cells. Chemistry & Biology. 18: 1620-30. PMID 22195564 DOI: 10.1016/J.Chembiol.2011.10.015 |
0.776 |
|
| 2011 |
Patel O, Pellicci DG, Uldrich AP, Sullivan LC, Bhati M, McKnight M, Richardson SK, Howell AR, Mallevaey T, Zhang J, Bedel R, Besra GS, Brooks AG, Kjer-Nielsen L, McCluskey J, et al. Vβ2 natural killer T cell antigen receptor-mediated recognition of CD1d-glycolipid antigen. Proceedings of the National Academy of Sciences of the United States of America. 108: 19007-12. PMID 22065767 DOI: 10.1073/Pnas.1109066108 |
0.321 |
|
| 2011 |
Liang Y, Hnatiuk N, Rowley JM, Whiting BT, Coates GW, Rablen PR, Morton M, Howell AR. Access to oxetane-containing psico-nucleosides from 2-methyleneoxetanes: a role for neighboring group participation? The Journal of Organic Chemistry. 76: 9962-74. PMID 22029375 DOI: 10.1021/Jo201565H |
0.777 |
|
| 2011 |
Arora P, Venkataswamy MM, Baena A, Bricard G, Li Q, Veerapen N, Ndonye R, Park JJ, Lee JH, Seo KC, Howell AR, Chang YT, Illarionov PA, Besra GS, Chung SK, et al. A rapid fluorescence-based assay for classification of iNKT cell activating glycolipids. Journal of the American Chemical Society. 133: 5198-201. PMID 21425779 DOI: 10.1021/Ja200070U |
0.78 |
|
| 2011 |
Wun KS, Cameron G, Patel O, Pang SS, Pellicci DG, Sullivan LC, Keshipeddy S, Young MH, Uldrich AP, Thakur MS, Richardson SK, Howell AR, Illarionov PA, Brooks AG, Besra GS, et al. A molecular basis for the exquisite CD1d-restricted antigen specificity and functional responses of natural killer T cells. Immunity. 34: 327-39. PMID 21376639 DOI: 10.1016/J.Immuni.2011.02.001 |
0.793 |
|
| 2011 |
O'Konek JJ, Illarionov P, Khursigara DS, Ambrosino E, Izhak L, Castillo BF, Raju R, Khalili M, Kim HY, Howell AR, Besra GS, Porcelli SA, Berzofsky JA, Terabe M. Mouse and human iNKT cell agonist β-mannosylceramide reveals a distinct mechanism of tumor immunity. The Journal of Clinical Investigation. 121: 683-94. PMID 21245578 DOI: 10.1172/Jci42314 |
0.684 |
|
| 2011 |
O'Konek JJ, Illarinov P, Khursigara DS, Ambrosino E, Izhak L, Castillo BF, Raju R, Khalili M, Kim H, Howell A, Besra GS, Porcelli SA, Berzofsky JA, Terabe M. Abstract 4746: Type I NKT cells mediate anti-tumor immunity through a TNF-α- and NOS-dependent pathway when stimulated with β-ManCer Cancer Research. 71: 4746-4746. DOI: 10.1158/1538-7445.Am2011-4746 |
0.697 |
|
| 2010 |
Bricard G, Venkataswamy MM, Yu KO, Im JS, Ndonye RM, Howell AR, Veerapen N, Illarionov PA, Besra GS, Li Q, Chang YT, Porcelli SA. Α-galactosylceramide analogs with weak agonist activity for human iNKT cells define new candidate anti-inflammatory agents. Plos One. 5: e14374. PMID 21179412 DOI: 10.1371/Journal.Pone.0014374 |
0.794 |
|
| 2010 |
Farber E, Herget J, Gascón JA, Howell AR. Unexpected cleavage of 2-azido-2-(hydroxymethyl)oxetanes: conformation determines reaction pathway? The Journal of Organic Chemistry. 75: 7565-72. PMID 20954693 DOI: 10.1021/Jo101328C |
0.777 |
|
| 2010 |
Lombardi V, Stock P, Singh AK, Kerzerho J, Yang W, Sullivan BA, Li X, Shiratsuchi T, Hnatiuk NE, Howell AR, Yu KO, Porcelli SA, Tsuji M, Kronenberg M, Wilson SB, et al. A CD1d-dependent antagonist inhibits the activation of invariant NKT cells and prevents development of allergen-induced airway hyperreactivity. Journal of Immunology (Baltimore, Md. : 1950). 184: 2107-15. PMID 20083656 DOI: 10.4049/Jimmunol.0901208 |
0.778 |
|
| 2010 |
O'Konek JJ, Illarionov P, Khursigara DS, Ambrosino E, Castillo BF, Raju R, Khalili M, Kim H, Howell AR, Besra GS, Porcelli SA, Berzofsky JA, Terabe M. Abstract 5613: Beta-mannosylceramide: a novel NKT cell agonist which synergizes with alpha-galactocylceramide to induce protection against tumors Cancer Research. 70: 5613-5613. DOI: 10.1158/1538-7445.Am10-5613 |
0.702 |
|
| 2010 |
Howell A, Keshipeddy S, Shi Y, Hnatiuk N, Morton M, Yao X. Design and Synthesis of an Activity-Based Probe Template for Protein Kinases Synlett. 2010: 1142-1142. DOI: 10.1055/S-0029-1219805 |
0.76 |
|
| 2009 |
Florence WC, Xia C, Gordy LE, Chen W, Zhang Y, Scott-Browne J, Kinjo Y, Yu KO, Keshipeddy S, Pellicci DG, Patel O, Kjer-Nielsen L, McCluskey J, Godfrey DI, Rossjohn J, ... ... Howell AR, et al. Adaptability of the semi-invariant natural killer T-cell receptor towards structurally diverse CD1d-restricted ligands. The Embo Journal. 28: 3781. PMID 19953109 DOI: 10.1038/Emboj.2009.348 |
0.721 |
|
| 2009 |
Fox LM, Cox DG, Lockridge JL, Wang X, Chen X, Scharf L, Trott DL, Ndonye RM, Veerapen N, Besra GS, Howell AR, Cook ME, Adams EJ, Hildebrand WH, Gumperz JE. Recognition of lyso-phospholipids by human natural killer T lymphocytes. Plos Biology. 7: e1000228. PMID 19859526 DOI: 10.1371/Journal.Pbio.1000228 |
0.788 |
|
| 2009 |
Florence WC, Xia C, Gordy LE, Chen W, Zhang Y, Scott-Browne J, Kinjo Y, Yu KO, Keshipeddy S, Pellicci DG, Patel O, Kjer-Nielsen L, McCluskey J, Godfrey DI, Rossjohn J, ... ... Howell AR, et al. Adaptability of the semi-invariant natural killer T-cell receptor towards structurally diverse CD1d-restricted ligands. The Embo Journal. 28: 3579-90. PMID 19816402 DOI: 10.1038/Emboj.2009.286 |
0.721 |
|
| 2009 |
Mallevaey T, Scott-Browne JP, Matsuda JL, Young MH, Pellicci DG, Patel O, Thakur M, Kjer-Nielsen L, Richardson SK, Cerundolo V, Howell AR, McCluskey J, Godfrey DI, Rossjohn J, Marrack P, et al. T cell receptor CDR2 beta and CDR3 beta loops collaborate functionally to shape the iNKT cell repertoire. Immunity. 31: 60-71. PMID 19592274 DOI: 10.1016/J.Immuni.2009.05.010 |
0.598 |
|
| 2009 |
Im JS, Arora P, Bricard G, Molano A, Venkataswamy MM, Baine I, Jerud ES, Goldberg MF, Baena A, Yu KOA, Ndonye RM, Howell AR, Yuan W, Cresswell P, Chang Yt, et al. Kinetics and Cellular Site of Glycolipid Loading Control the Outcome of Natural Killer T Cell Activation Immunity. 30: 888-898. PMID 19538930 DOI: 10.1016/J.Immuni.2009.03.022 |
0.79 |
|
| 2009 |
Raju R, Castillo BF, Richardson SK, Thakur M, Severins R, Kronenberg M, Howell AR. Synthesis and evaluation of 3''- and 4''-deoxy and -fluoro analogs of the immunostimulatory glycolipid, KRN7000. Bioorganic & Medicinal Chemistry Letters. 19: 4122-5. PMID 19535248 DOI: 10.1016/J.Bmcl.2009.06.005 |
0.634 |
|
| 2009 |
Velmourougane G, Raju R, Bricard G, Im JS, Besra GS, Porcelli SA, Howell AR. Synthesis and evaluation of an acyl-chain unsaturated analog of the Th2 biasing, immunostimulatory glycolipid, OCH. Bioorganic & Medicinal Chemistry Letters. 19: 3386-8. PMID 19481452 DOI: 10.1016/J.Bmcl.2009.05.042 |
0.334 |
|
| 2009 |
Howell A, Keshipeddy S, Shi Y, Hnatiuk N, Morton M, Yao X. Design and Synthesis of an Activity-Based Probe Template for Protein Kinases Synlett. 2010: 521-524. DOI: 10.1055/S-0029-1218543 |
0.757 |
|
| 2009 |
Liang Y, Raju R, Le T, Taylor CD, Howell AR. Cross-metathesis of α-methylene-β-lactams: the first tetrasubstituted alkenes by CM Tetrahedron Letters. 50: 1020-1022. DOI: 10.1016/J.Tetlet.2008.12.060 |
0.736 |
|
| 2008 |
Blauvelt ML, Khalili M, Jaung W, Paulsen J, Anderson AC, Brian Wilson S, Howell AR. Alpha-S-GalCer: synthesis and evaluation for iNKT cell stimulation. Bioorganic & Medicinal Chemistry Letters. 18: 6374-6. PMID 18993065 DOI: 10.1016/J.Bmcl.2008.10.086 |
0.759 |
|
| 2008 |
Vas J, Mattner J, Richardson S, Ndonye R, Gaughan JP, Howell A, Monestier M. Regulatory roles for NKT cell ligands in environmentally induced autoimmunity. Journal of Immunology (Baltimore, Md. : 1950). 181: 6779-88. PMID 18981095 DOI: 10.4049/Jimmunol.181.10.6779 |
0.774 |
|
| 2008 |
Wang X, Chen X, Rodenkirch L, Simonson W, Wernimont S, Ndonye RM, Veerapen N, Gibson D, Howell AR, Besra GS, Painter GF, Huttenlocher A, Gumperz JE. Natural killer T-cell autoreactivity leads to a specialized activation state. Blood. 112: 4128-38. PMID 18779390 DOI: 10.1182/Blood-2008-05-157529 |
0.786 |
|
| 2008 |
Kinjo Y, Pei B, Bufali S, Raju R, Richardson SK, Imamura M, Fujio M, Wu D, Khurana A, Kawahara K, Wong CH, Howell AR, Seeberger PH, Kronenberg M. Natural Sphingomonas glycolipids vary greatly in their ability to activate natural killer T cells. Chemistry & Biology. 15: 654-64. PMID 18635002 DOI: 10.1016/J.Chembiol.2008.05.012 |
0.38 |
|
| 2008 |
Wun KS, Borg NA, Kjer-Nielsen L, Beddoe T, Koh R, Richardson SK, Thakur M, Howell AR, Scott-Browne JP, Gapin L, Godfrey DI, McCluskey J, Rossjohn J. A minimal binding footprint on CD1d-glycolipid is a basis for selection of the unique human NKT TCR. The Journal of Experimental Medicine. 205: 939-49. PMID 18378792 DOI: 10.1084/Jem.20072141 |
0.628 |
|
| 2008 |
Blauvelt ML, Howell AR. Synthesis of epi-oxetin via a serine-derived 2-methyleneoxetane. The Journal of Organic Chemistry. 73: 517-21. PMID 18092802 DOI: 10.1021/Jo7018762 |
0.769 |
|
| 2007 |
Li Q, Ndonye RM, Illarionov PA, Yu KO, Jerud ES, Diaz K, Bricard G, Porcelli SA, Besra GS, Chang YT, Howell AR. Rapid identification of immunostimulatory alpha-galactosylceramides using synthetic combinatorial libraries. Journal of Combinatorial Chemistry. 9: 1084-93. PMID 17896821 DOI: 10.1021/Cc070057I |
0.802 |
|
| 2007 |
Yu KO, Im JS, Illarionov PA, Ndonye RM, Howell AR, Besra GS, Porcelli SA. Production and characterization of monoclonal antibodies against complexes of the NKT cell ligand alpha-galactosylceramide bound to mouse CD1d. Journal of Immunological Methods. 323: 11-23. PMID 17442335 DOI: 10.1016/J.Jim.2007.03.006 |
0.781 |
|
| 2007 |
Raju R, Allen LJ, Le T, Taylor CD, Howell AR. Cross metathesis of alpha-methylene lactones II: gamma- and delta-lactones. Organic Letters. 9: 1699-701. PMID 17407303 DOI: 10.1021/Ol070574+ |
0.353 |
|
| 2007 |
Forestier C, Takaki T, Molano A, Im JS, Baine I, Jerud ES, Illarionov P, Ndonye R, Howell AR, Santamaria P, Besra GS, Dilorenzo TP, Porcelli SA. Improved outcomes in NOD mice treated with a novel Th2 cytokine-biasing NKT cell activator. Journal of Immunology (Baltimore, Md. : 1950). 178: 1415-25. PMID 17237389 DOI: 10.4049/Jimmunol.178.3.1415 |
0.778 |
|
| 2007 |
Howell A, Richardson S. Synthesis and Reactions of 2-Alkylidene Thiiranes and Thietanes Synthesis. 2007: 2755-2778. DOI: 10.1055/S-2007-983883 |
0.343 |
|
| 2007 |
Sabila PS, Liang Y, Howell AR. 3-Silyloxytetrahydrofurans via sulfoxonium ylide reactions with α-silyloxyepoxides Tetrahedron Letters. 48: 8356-8359. DOI: 10.1016/J.Tetlet.2007.09.113 |
0.778 |
|
| 2007 |
Sabila PS, Howell AR. 2-Alkylidene oxetanes by stereospecific elimination of mesylates Tetrahedron Letters. 48: 8353-8355. DOI: 10.1016/J.Tetlet.2007.09.109 |
0.772 |
|
| 2006 |
Raju R, Howell AR. Cross metathesis with strained exocyclic enones: synthesis of 3-alkylideneoxetan-2-ones from 3-methyleneoxetan-2-ones. Organic Letters. 8: 2139-41. PMID 16671801 DOI: 10.1002/CHIN.200637092 |
0.316 |
|
| 2006 |
Matsuda JL, Zhang Q, Ndonye R, Richardson SK, Howell AR, Gapin L. T-bet concomitantly controls migration, survival, and effector functions during the development of Valpha14i NKT cells. Blood. 107: 2797-805. PMID 16357323 DOI: 10.1182/Blood-2005-08-3103 |
0.777 |
|
| 2006 |
Richardson SK, Howell AR, Taboada R. Synthesis and Properties of psico-Nucleosides Cheminform. 37. DOI: 10.1080/00304940609355987 |
0.782 |
|
| 2005 |
Ndonye RM, Izmirian DP, Dunn MF, Yu KO, Porcelli SA, Khurana A, Kronenberg M, Richardson SK, Howell AR. Synthesis and evaluation of sphinganine analogues of KRN7000 and OCH. The Journal of Organic Chemistry. 70: 10260-70. PMID 16323834 DOI: 10.1021/Jo051147H |
0.79 |
|
| 2005 |
Basu S, Cunningham LP, Pins GD, Bush KA, Taboada R, Howell AR, Wang J, Campagnola PJ. Multiphoton excited fabrication of collagen matrixes cross-linked by a modified benzophenone dimer: bioactivity and enzymatic degradation. Biomacromolecules. 6: 1465-74. PMID 15877366 DOI: 10.1021/Bm049258Y |
0.766 |
|
| 2005 |
Howell AR, So RC, Richardson SK. Approaches to the Preparation of Sphinganines Cheminform. 36. DOI: 10.1016/J.Tet.2004.09.056 |
0.738 |
|
| 2004 |
Sidobre S, Hammond KJ, Bénazet-Sidobre L, Maltsev SD, Richardson SK, Ndonye RM, Howell AR, Sakai T, Besra GS, Porcelli SA, Kronenberg M. The T cell antigen receptor expressed by Valpha14i NKT cells has a unique mode of glycosphingolipid antigen recognition. Proceedings of the National Academy of Sciences of the United States of America. 101: 12254-9. PMID 15304644 DOI: 10.1073/Pnas.0404632101 |
0.792 |
|
| 2004 |
So RC, Ndonye R, Izmirian DP, Richardson SK, Guerrera RL, Howell AR. Straightforward synthesis of sphinganines via a serine-derived Weinreb amide. The Journal of Organic Chemistry. 69: 3233-5. PMID 15104474 DOI: 10.1021/Jo030355B |
0.786 |
|
| 2004 |
Howell AR, So RC, Richardson SK. Approaches to the preparation of sphinganines Tetrahedron. 60: 11327-11347. DOI: 10.1016/J.TET.2004.09.056 |
0.724 |
|
| 2003 |
Taboada R, Ordonio GG, Ndakala AJ, Howell AR, Rablen PR. Directed ring-opening of 1,5-dioxaspiro[3.2]hexanes: selective formation of 2,2-disubstituted oxetanes. The Journal of Organic Chemistry. 68: 1480-8. PMID 12585892 DOI: 10.1021/Jo0206465 |
0.788 |
|
| 2003 |
Martínez I, Andrews AE, Emch JD, Ndakala AJ, Wang J, Howell AR. Unusual, strained heterocycles: 3-alkylidene-2-methyleneoxetanes from Morita-Baylis-Hillman-type adducts. Organic Letters. 5: 399-402. PMID 12583728 DOI: 10.1021/Ol020202V |
0.709 |
|
| 2003 |
Wang Y, Bekolo H, Howell AR. Ring Opening Reactions of 2-Methyleneoxetanes. Cheminform. 34. DOI: 10.1016/S0040-4020(02)00724-X |
0.338 |
|
| 2002 |
Pitts JD, Howell AR, Taboada R, Banerjee I, Wang J, Goodman SL, Campagnola PJ. New photoactivators for multiphoton excited three-dimensional submicron cross-linking of proteins: bovine serum albumin and type 1 collagen. Photochemistry and Photobiology. 76: 135-44. PMID 12194208 DOI: 10.1562/0031-8655(2002)076<0135:Npfmet>2.0.Co;2 |
0.776 |
|
| 2002 |
Ndakala AJ, Hashemzadeh M, So RC, Howell AR. Synthesis of D-erythro-dihydrosphingosine and D-xylo-phytosphingosine from a serine-derived 1,5-dioxaspiro[3.2]hexane template. Organic Letters. 4: 1719-22. PMID 12000282 DOI: 10.1021/Ol0200448 |
0.762 |
|
| 2002 |
Howell A, Ndakala A. The Preparation and Biological Significance of Phytosphingosines Current Organic Chemistry. 6: 365-391. DOI: 10.2174/1385272024604998 |
0.701 |
|
| 2001 |
Bekolo H, Howell AR. Preparation and reactions of 4-oxaspiro[2.3]hexanes New Journal of Chemistry. 25: 673-675. DOI: 10.1039/B010095L |
0.327 |
|
| 2000 |
Martı́nez I, Howell AR. The reaction of dimethyltitanocene with N-substituted-β-lactams Tetrahedron Letters. 41: 5607-5611. DOI: 10.1016/S0040-4039(00)00919-9 |
0.331 |
|
| 2000 |
Hashemzadeh M, Howell AR. An unusual and efficient reaction of 2-methylene-3-phenyloxetane in the presence of lithium and 4,4′-di-tert-butylbiphenyl in THF Tetrahedron Letters. 41: 1859-1862. DOI: 10.1016/S0040-4039(00)00060-5 |
0.333 |
|
| 2000 |
Hashemzadeh M, Howell AR. Reductive cleavage of 2-methyleneoxetanes with lithium and 4,4′-di-tert-butylbiphenyl Tetrahedron Letters. 41: 1855-1858. DOI: 10.1016/S0040-4039(00)00059-9 |
0.348 |
|
| 1999 |
Howell AR, Ndakala AJ. Ring Opening of 1,5-Dioxaspiro[3.2]hexanes: Selective Preparation of α-Heterofunctionalized-β‘-hydroxy Ketones or 2,2-Disubstituted Oxetanes Organic Letters. 1: 825-827. DOI: 10.1021/Ol990039C |
0.715 |
|
| 1999 |
Dollinger LM, Ndakala AJ, Hashemzadeh M, Wang G, Wang Y, Martinez I, Arcari JT, Galluzzo DJ, Howell AR, Rheingold AL, Figuero JS. Preparation and Properties of 2-Methyleneoxetanes The Journal of Organic Chemistry. 64: 7074-7080. DOI: 10.1021/Jo9906072 |
0.725 |
|
| 1998 |
Ndakala AJ, Howell AR. The First General Synthesis of 1,5-Dioxaspiro[3.2]hexanes. The Journal of Organic Chemistry. 63: 6098-6099. PMID 11672233 DOI: 10.1021/Jo981309S |
0.715 |
|
| 1996 |
Howell AR, Fan R, Truong A. Preparation of 2-Alkylidene oxetanes: An investigation of the Paterno-Buchi reaction between aliphatic aldehydes and allenes Tetrahedron Letters. 37: 8651-8654. DOI: 10.1016/S0040-4039(96)02001-1 |
0.311 |
|
| 1991 |
Howell AR, Martin WR, Sloan JW, Smith WT. Synthesis and binding activity of 4-azanicotine Journal of Heterocyclic Chemistry. 28: 1147-1151. DOI: 10.1002/Jhet.5570280453 |
0.645 |
|
| 1990 |
Bhandal H, Howell AR, Patel VF, Pattenden G. Cobalt-mediated intermolecular radical additions to carbon-to-carbon double bonds leading to new functionalised alkenes Journal of the Chemical Society-Perkin Transactions 1. 2709-2714. DOI: 10.1039/P19900002709 |
0.301 |
|
| 1989 |
Barrett AGM, Bezuidenhoudt BCB, Gasiecki AF, Howell AR, Russell MA. Redox glycosidation: a new strategy for disaccharide synthesis Journal of the American Chemical Society. 111: 1392-1396. DOI: 10.1021/Ja00186A037 |
0.303 |
|
| 1985 |
Sloan JW, Martin WR, Hook R, Bostwick M, Howell A, Smith WT. Stereospecificity of 2-methylpiperidine binding to a nicotinic up-regulatory site in the rat brain P2 preparation Life Sciences. 37: 1367-1372. PMID 4046738 DOI: 10.1016/0024-3205(85)90074-8 |
0.616 |
|
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