Gaynor A Smith - Publications

Cardiff University, Cardiff, Wales, United Kingdom 
Drosophila, Parkinson's disease, Huntington's disease, mitochondria

18/21 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Breger LS, Kienle K, Smith GA, Dunnett SB, Lane EL. Influence of chronic L-DOPA treatment on immune response following allogeneic and xenogeneic graft in a rat model of Parkinson's disease. Brain, Behavior, and Immunity. PMID 27864045 DOI: 10.1016/j.bbi.2016.11.014  0.64
2015 Rocha EM, Smith GA, Park E, Cao H, Brown E, Hayes MA, Beagan J, McLean JR, Izen SC, Perez-Torres E, Hallett PJ, Isacson O. Glucocerebrosidase gene therapy prevents α-synucleinopathy of midbrain dopamine neurons. Neurobiology of Disease. PMID 26392287 DOI: 10.1016/j.nbd.2015.09.009  0.56
2015 Rocha EM, Smith GA, Park E, Cao H, Graham AR, Brown E, McLean JR, Hayes MA, Beagan J, Izen SC, Perez-Torres E, Hallett PJ, Isacson O. Chronic pharmacological glucocerebrosidase inhibition induces α-synuclein aggregation, microglial and complement activation and synaptic protein changes in mice. Antioxidants & Redox Signaling. PMID 26094487 DOI: 10.1089/ars.2015.6307  0.56
2015 Rocha EM, Smith GA, Park E, Cao H, Brown E, Hallett P, Isacson O. Progressive decline of glucocerebrosidase in aging and Parkinson's disease. Annals of Clinical and Translational Neurology. 2: 433-8. PMID 25909088 DOI: 10.1002/acn3.177  0.44
2015 Smith GA, Rocha EM, Rooney T, Barneoud P, McLean JR, Beagan J, Osborn T, Coimbra M, Luo Y, Hallett PJ, Isacson O. A Nurr1 agonist causes neuroprotection in a Parkinson's disease lesion model primed with the toll-like receptor 3 dsRNA inflammatory stimulant poly(I:C). Plos One. 10: e0121072. PMID 25815475 DOI: 10.1371/journal.pone.0121072  0.56
2015 Hallett PJ, Deleidi M, Astradsson A, Smith GA, Cooper O, Osborn TM, Sundberg M, Moore MA, Perez-Torres E, Brownell AL, Schumacher JM, Spealman RD, Isacson O. Successful function of autologous iPSC-derived dopamine neurons following transplantation in a non-human primate model of Parkinson's disease. Cell Stem Cell. 16: 269-74. PMID 25732245 DOI: 10.1016/j.stem.2015.01.018  0.56
2014 McLean JR, Smith GA, Rocha EM, Osborn TM, Dib S, Hayes MA, Beagan JA, Brown TB, Lawson TF, Hallett PJ, Robertson J, Isacson O. ALS-associated peripherin spliced transcripts form distinct protein inclusions that are neuroprotective against oxidative stress. Experimental Neurology. 261: 217-29. PMID 24907400 DOI: 10.1016/j.expneurol.2014.05.024  0.56
2014 McLean JR, Smith GA, Rocha EM, Hayes MA, Beagan JA, Hallett PJ, Isacson O. Widespread neuron-specific transgene expression in brain and spinal cord following synapsin promoter-driven AAV9 neonatal intracerebroventricular injection. Neuroscience Letters. 576: 73-8. PMID 24882721 DOI: 10.1016/j.neulet.2014.05.044  0.56
2014 Smith GA, Rocha EM, McLean JR, Hayes MA, Izen SC, Isacson O, Hallett PJ. Progressive axonal transport and synaptic protein changes correlate with behavioral and neuropathological abnormalities in the heterozygous Q175 KI mouse model of Huntington's disease. Human Molecular Genetics. 23: 4510-27. PMID 24728190 DOI: 10.1093/hmg/ddu166  0.56
2013 Smith GA, Snyder EY. Two cells are better than one: optimizing stem cell survival by co-grafting "helper" cells that offer regulated trophic support. Experimental Neurology. 247: 751-4. PMID 23856435 DOI: 10.1016/j.expneurol.2013.07.003  0.56
2013 Peters OM, Shelkovnikova T, Tarasova T, Springe S, Kukharsky MS, Smith GA, Brooks S, Kozin SA, Kotelevtsev Y, Bachurin SO, Ninkina N, Buchman VL. Chronic administration of Dimebon does not ameliorate amyloid-β pathology in 5xFAD transgenic mice. Journal of Alzheimer's Disease : Jad. 36: 589-96. PMID 23645096 DOI: 10.3233/JAD-130071  0.56
2013 Heuer A, Smith GA, Dunnett SB. Comparison of 6-hydroxydopamine lesions of the substantia nigra and the medial forebrain bundle on a lateralised choice reaction time task in mice. The European Journal of Neuroscience. 37: 294-302. PMID 23113688 DOI: 10.1111/ejn.12036  0.56
2012 Smith GA, Heuer A, Klein A, Vinh NN, Dunnett SB, Lane EL. Amphetamine-induced dyskinesia in the transplanted hemi-Parkinsonian mouse. Journal of Parkinson's Disease. 2: 107-13. PMID 23933747 DOI: 10.3233/JPD-2012-12102  0.56
2012 Smith GA, Isacson O, Dunnett SB. The search for genetic mouse models of prodromal Parkinson's disease. Experimental Neurology. 237: 267-73. PMID 22819262 DOI: 10.1016/j.expneurol.2012.06.035  0.56
2012 Smith GA, Breger LS, Lane EL, Dunnett SB. Pharmacological modulation of amphetamine-induced dyskinesia in transplanted hemi-parkinsonian rats. Neuropharmacology. 63: 818-28. PMID 22722025 DOI: 10.1016/j.neuropharm.2012.06.011  0.56
2012 Smith GA, Dunnett SB, Lane EL. Amphetamine-induced rotation in the transplanted hemi-parkinsonian rat--response to pharmacological modulation. Behavioural Brain Research. 232: 411-5. PMID 22516841 DOI: 10.1016/j.bbr.2012.04.003  0.56
2012 Heuer A, Smith GA, Lelos MJ, Lane EL, Dunnett SB. Unilateral nigrostriatal 6-hydroxydopamine lesions in mice I: motor impairments identify extent of dopamine depletion at three different lesion sites. Behavioural Brain Research. 228: 30-43. PMID 22146593 DOI: 10.1016/j.bbr.2011.11.027  0.56
2012 Smith GA, Heuer A, Dunnett SB, Lane EL. Unilateral nigrostriatal 6-hydroxydopamine lesions in mice II: predicting l-DOPA-induced dyskinesia. Behavioural Brain Research. 226: 281-92. PMID 21946310 DOI: 10.1016/j.bbr.2011.09.025  0.56
Low-probability matches
2019 Smith GA, Lin TH, Sheehan AE, Van der Goes van Naters W, Neukomm LJ, Graves HK, Bis-Brewer DM, Züchner S, Freeman MR. Glutathione S-Transferase Regulates Mitochondrial Populations in Axons through Increased Glutathione Oxidation. Neuron. PMID 31101394 DOI: 10.1016/j.neuron.2019.04.017  0.28
2019 Malik BR, Maddison DC, Smith GA, Peters OM. Autophagic and endo-lysosomal dysfunction in neurodegenerative disease. Molecular Brain. 12: 100. PMID 31783880 DOI: 10.1186/s13041-019-0504-x  0.08
2015 Lewis EA, Smith GA. Using Drosophila models of Huntington's disease as a translatable tool. Journal of Neuroscience Methods. PMID 26241927 DOI: 10.1016/j.jneumeth.2015.07.026  0.01
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