Year |
Citation |
Score |
2019 |
Xu S, Yang L, Kompella SN, Tae H, Zhang T, Lv A, Wang Y, Shao X, Ding J, Adams DJ, Wang C. Dissecting the nachr-inhibiting D-conotoxin GeXXA Toxicon. 158: S26. DOI: 10.1016/J.Toxicon.2018.10.095 |
0.674 |
|
2017 |
Cuny H, Yu R, Tae HS, Kompella SN, Adams DJ. α-Conotoxins active at α3-containing nicotinic acetylcholine receptors and their molecular determinants for selective inhibition. British Journal of Pharmacology. PMID 28477355 DOI: 10.1111/Bph.13852 |
0.744 |
|
2016 |
Cuny H, Kompella SN, Tae HS, Yu R, Adams DJ. Key Structural Determinants in the Agonist Binding Loops of Human β2 and β4 Nicotinic Acetylcholine Receptor Subunits Contribute to α3β4 Subtype Selectivity of α-Conotoxins. The Journal of Biological Chemistry. PMID 27646000 DOI: 10.1074/Jbc.M116.730804 |
0.718 |
|
2015 |
Kompella SN, Cuny H, Hung A, Adams DJ. Molecular Basis for Differential Sensitivity of α-Conotoxin RegIIA at Rat and Human Neuronal Nicotinic Acetylcholine Receptors. Molecular Pharmacology. 88: 993-1001. PMID 26438212 DOI: 10.1124/Mol.115.100503 |
0.784 |
|
2015 |
Xu S, Zhang T, Kompella SN, Yan M, Lu A, Wang Y, Shao X, Chi C, Adams DJ, Ding J, Wang C. Conotoxin αD-GeXXA utilizes a novel strategy to antagonize nicotinic acetylcholine receptors. Scientific Reports. 5: 14261. PMID 26395518 DOI: 10.1038/Srep14261 |
0.621 |
|
2015 |
Kompella SN, Hung A, Clark RJ, Marí F, Adams DJ. Alanine scan of α-conotoxin RegIIA reveals a selective α3β4 nicotinic acetylcholine receptor antagonist. The Journal of Biological Chemistry. 290: 1039-48. PMID 25411242 DOI: 10.1074/Jbc.M114.605592 |
0.698 |
|
2014 |
Chhabra S, Belgi A, Bartels P, van Lierop BJ, Robinson SD, Kompella SN, Hung A, Callaghan BP, Adams DJ, Robinson AJ, Norton RS. Dicarba analogues of α-conotoxin RgIA. Structure, stability, and activity at potential pain targets. Journal of Medicinal Chemistry. 57: 9933-44. PMID 25393758 DOI: 10.1021/Jm501126U |
0.75 |
|
2013 |
Inserra MC, Kompella SN, Vetter I, Brust A, Daly NL, Cuny H, Craik DJ, Alewood PF, Adams DJ, Lewis RJ. Isolation and characterization of α-conotoxin LsIA with potent activity at nicotinic acetylcholine receptors. Biochemical Pharmacology. 86: 791-9. PMID 23924607 DOI: 10.1016/J.Bcp.2013.07.016 |
0.75 |
|
2013 |
van Lierop BJ, Robinson SD, Kompella SN, Belgi A, McArthur JR, Hung A, MacRaild CA, Adams DJ, Norton RS, Robinson AJ. Dicarba α-conotoxin Vc1.1 analogues with differential selectivity for nicotinic acetylcholine and GABAB receptors. Acs Chemical Biology. 8: 1815-21. PMID 23768016 DOI: 10.1021/Cb4002393 |
0.747 |
|
2013 |
Yu R, Kompella SN, Adams DJ, Craik DJ, Kaas Q. Determination of the α-conotoxin Vc1.1 binding site on the α9α10 nicotinic acetylcholine receptor. Journal of Medicinal Chemistry. 56: 3557-67. PMID 23566299 DOI: 10.1021/Jm400041H |
0.524 |
|
2013 |
Kompella SN, Hung A, Clark RJ, Adams DJ. α-Conotoxin Regiia Targeting Nicotinic Acetylcholine Receptors: Mutagenesis Studies Improving Selectivity and Potency Biophysical Journal. 104: 634a. DOI: 10.1016/J.Bpj.2012.11.3505 |
0.717 |
|
2013 |
Kompella S, van Lierop B, Robinson S, Belgi A, Callaghan B, Hung A, MacRaild C, Norton R, Robinson A, Adams D. Dicarba modification of α-conotoxin RgIA conferring selectivity towards α9α10 nicotinic acetylcholine receptors Biochemical Pharmacology. 86: 1230. DOI: 10.1016/J.Bcp.2013.08.043 |
0.75 |
|
2013 |
Kompella S, Xu S, Zhang T, Yan M, Shao X, Chi C, Ding J, Wang C, Adams D. Novel strategy of blocking nAChR revealed by dissecting a dimeric conotoxin αD-GeXXA Biochemical Pharmacology. 86: 1229. DOI: 10.1016/J.Bcp.2013.08.041 |
0.554 |
|
2012 |
Franco A, Kompella SN, Akondi KB, Melaun C, Daly NL, Luetje CW, Alewood PF, Craik DJ, Adams DJ, Marà F. RegIIA: an α4/7-conotoxin from the venom of Conus regius that potently blocks α3β4 nAChRs. Biochemical Pharmacology. 83: 419-26. PMID 22108175 DOI: 10.1016/J.Bcp.2011.11.006 |
0.646 |
|
2011 |
Safavi-Hemami H, Siero WA, Kuang Z, Williamson NA, Karas JA, Page LR, MacMillan D, Callaghan B, Kompella SN, Adams DJ, Norton RS, Purcell AW. Embryonic toxin expression in the cone snail Conus victoriae: primed to kill or divergent function? The Journal of Biological Chemistry. 286: 22546-57. PMID 21504902 DOI: 10.1074/Jbc.M110.217703 |
0.632 |
|
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