Charles F. Barfknecht - Publications

Affiliations: 
Medicinal Chemistry University of Iowa, Iowa City, IA 
Area:
Pharmacy, Ophthalmology, Pharmaceutical Chemistry, Pharmacology

78 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2000 Deshpande G, Schoenwald RD, Barfknecht CF, Duffel MW. In vitro and ex vivo hydrolysis rates of ethacrynate esters and their relationship to intraocular pressure in the rabbit eye. Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association For Ocular Pharmacology and Therapeutics. 16: 539-56. PMID 11132901  1
1998 Schoenwald RD, Tandon V, Wurster DE, Barfknecht CF. Significance of melanin binding and metabolism in the activity of 5-acetoxyacetylimino-4-methyl-delta2-1,3,4,-thiadiazolin e-2-sulfonamide. European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft FüR Pharmazeutische Verfahrenstechnik E.V. 46: 39-50. PMID 9700021 DOI: 10.1016/S0939-6411(97)00166-5  1
1998 Schoenwald RD, Yang YS, Xia E, Barfknecht CF. Uptake of N,N-dimethyl-2-phenylethylene HCl into acini cells removed from rabbit lacrimal glands. Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association For Ocular Pharmacology and Therapeutics. 14: 253-62. PMID 9671433  1
1998 Schoenwald RD, Vidvauns S, Wurster DE, Barfknecht CF. The role of tear proteins in tear film stability in the dry eye patient and in the rabbit. Advances in Experimental Medicine and Biology. 438: 391-400. PMID 9634912  1
1998 Schoenwald RD, Vidvauns S, Wurster DE, Barfknecht CF. The influence of tear proteins on the film stability of rabbit tear extracts. Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association For Ocular Pharmacology and Therapeutics. 14: 15-29. PMID 9493780  1
1997 Schoenwald RD, Vidvauns S, Wurster DE, Barfknecht CF. Tear film stability of protein extracts from dry eye patients administered a sigma agonist. Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association For Ocular Pharmacology and Therapeutics. 13: 151-61. PMID 9090615  1
1997 Schoenwald RD, Deshpande GS, Rethwisch DG, Barfknecht CF. Penetration into the anterior chamber via the conjunctival/scleral pathway. Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association For Ocular Pharmacology and Therapeutics. 13: 41-59. PMID 9029439  1
1997 Schoenwald RD, Gadiraju RR, Barfknecht CF. Serotonin antagonists for use as antiglaucoma agents and their ocular penetration European Journal of Pharmaceutics and Biopharmaceutics. 43: 273-281. DOI: 10.1016/S0939-6411(97)00055-6  1
1995 Schoenwald RD, Barfknecht CF, Shirolkar S, Xia E. The effects of sigma ligands on protein release from lacrimal acinar cells: a potential agonist/antagonist assay. Life Sciences. 56: 1275-85. PMID 8614245 DOI: 10.1016/0024-3205(95)00073-9  1
1995 Shirolkar S, Schoenwald RD, Barfknecht CF, Yang YS, Vidvauns S. Determination of tolerance to tear protein release following a twice a day topical application of N,N-dimethyl-2-phenylethylamine HCl. Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association For Ocular Pharmacology and Therapeutics. 11: 41-7. PMID 8535956  1
1994 Schoenwald RD, Barfknecht CF, Shirolkar S, Xia E, Ignace CC. Identification of sigma receptors in lacrimocytes and their therapeutic implication in dry eye syndrome. Advances in Experimental Medicine and Biology. 350: 141-6. PMID 8030466  1
1993 Schoenwald RD, Barfknecht CF, Xia E, Newton RE. The presence of sigma-receptors in the lacrimal gland. Journal of Ocular Pharmacology. 9: 125-39. PMID 8345285  1
1993 Shirolkar S, Schoenwald RD, Barfknecht CF, Xia E, Cheng B, Iwai Y, Ignace CC, Vidvauns S, Newton RE. Lacrimal secretion stimulants: sigma receptors and drug implications. Journal of Ocular Pharmacology. 9: 211-27. PMID 8228530  1
1992 Rao CS, Schoenwald RD, Barfknecht CF, Laban SL. Biopharmaceutical evaluation of ibufenac, ibuprofen, and their hydroxyethoxy analogs in the rabbit eye. Journal of Pharmacokinetics and Biopharmaceutics. 20: 357-88. PMID 1479559 DOI: 10.1007/BF01062463  1
1992 Lee DY, Schoenwald RD, Barfknecht CF. Biopharmaceutical explanation for the topical activity of 6-hydroxyethoxy-2-benzothiazolesulfonamide in the rabbit eye. Journal of Ocular Pharmacology. 8: 247-65. PMID 1453087  1
1992 Ellingson CM, Schoenwald RD, Barfknecht CF, Rao CS, Laban SL. Rapid toxicological model for use in assessing ocular drugs. Biopharmaceutics & Drug Disposition. 13: 417-36. PMID 1382651  1
1991 Campbell DA, Schoenwald RD, Duffel MW, Barfknecht CF. Characterization of arylamine acetyltransferase in the rabbit eye. Investigative Ophthalmology & Visual Science. 32: 2190-200. PMID 2071333  1
1990 Richerson HB, Adams PA, Iwai Y, Barfknecht CF. Uptake of muramyl dipeptide fluorescent congeners by normal rabbit bronchoalveolar lavage cells: a study using flow cytometry. American Journal of Respiratory Cell and Molecular Biology. 2: 171-81. PMID 2306373 DOI: 10.1165/ajrcmb/2.2.171  1
1990 Richerson HB, Adams P, Iwai Y, Barfknecht CF. Uptake of muramyl dipeptide by alveolar macrophages in experimental hypersensitivity pneumonitis. American Journal of Industrial Medicine. 17: 120. PMID 2305780  1
1990 Hendricks RL, Barfknecht CF, Schoenwald RD, Epstein RJ, Sugar J. The effect of flurbiprofen on herpes simplex virus type 1 stromal keratitis in mice. Investigative Ophthalmology & Visual Science. 31: 1503-11. PMID 2167299  1
1988 Lewis RA, Schoenwald RD, Barfknecht CF. Aminozolamide suspension: the role of the vehicle in a topical carbonic anhydrase inhibitor. Journal of Ocular Pharmacology. 4: 215-9. PMID 3198983  1
1988 Hiebert CK, Kopp WC, Richerson HB, Barfknecht CF. Synthesis of fluorescent muramyl dipeptide congeners. 2. Journal of Medicinal Chemistry. 31: 2022-4. PMID 3172138  1
1987 Putnam ML, Schoenwald RD, Duffel MW, Barfknecht CF, Segarra TM, Campbell DA. Ocular disposition of aminozolamide in the rabbit eye. Investigative Ophthalmology & Visual Science. 28: 1373-82. PMID 3610554  1
1986 Duffel MW, Ing IS, Segarra TM, Dixson JA, Barfknecht CF, Schoenwald RD. N-Substituted sulfonamide carbonic anhydrase inhibitors with topical effects on intraocular pressure. Journal of Medicinal Chemistry. 29: 1488-94. PMID 3735316  1
1986 Lewis RA, Schoenwald RD, Barfknecht CF, Phelps CD. Aminozolamide gel. A trial of a topical carbonic anhydrase inhibitor in ocular hypertension. Archives of Ophthalmology (Chicago, Ill. : 1960). 104: 842-4. PMID 3521557  1
1985 Eller MG, Schoenwald RD, Dixson JA, Segarra T, Barfknecht CF. Topical carbonic anhydrase inhibitors IV: Relationship between excised corneal permeability and pharmacokinetic factors. Journal of Pharmaceutical Sciences. 74: 525-9. PMID 4020628 DOI: 10.1002/jps.2600740506  1
1985 Eller MG, Schoenwald RD, Dixson JA, Segarra T, Barfknecht CF. Topical carbonic anhydrase inhibitors. III: Optimization model for corneal penetration of ethoxzolamide analogues. Journal of Pharmaceutical Sciences. 74: 155-60. PMID 3989684 DOI: 10.1002/jps.2600740210  1
1984 Schoenwald RD, Eller MG, Dixson JA, Barfknecht CF. Topical carbonic anhydrase inhibitors. Journal of Medicinal Chemistry. 27: 810-2. PMID 6737424  1
1984 Lewis RA, Schoenwald RD, Eller MG, Barfknecht CF, Phelps CD. Ethoxzolamide analogue gel. A topical carbonic anhydrase inhibitor. Archives of Ophthalmology (Chicago, Ill. : 1960). 102: 1821-4. PMID 6548907 DOI: 10.1001/archopht.1984.01040031479027  1
1983 Hiebert CK, Kopp WC, Richerson HB, Barfknecht CF. Synthesis of a biologically active fluorescent muramyl dipeptide congener. Journal of Medicinal Chemistry. 26: 1729-32. PMID 6644742  1
1982 Arneri? SP, Maixner W, Long JP, Mott J, Barfknecht CF, Perez JA, Cannon JG. Structure-activity relationships of 2-aminotetralins and 2-aminoindanes: inhibitory neuroeffector mechanisms in isolated guinea-pig ilea. Archives Internationales De Pharmacodynamie Et De ThéRapie. 258: 84-99. PMID 7138147  1
1982 Arnerić SP, Roetker A, Long JP, Mott J, Barfknecht CF. Effects of semirigid methoxamine analogs on vascular smooth muscle: studies of methoxy-2-aminotetralin and 2-aminoindane derivatives. Archives Internationales De Pharmacodynamie Et De ThéRapie. 257: 263-73. PMID 7114973  1
1982 Sindelar RD, Mott J, Barfknecht CF, Arneric SP, Flynn JR, Long JP, Bhatnagar RK. 2-Amino-4,7-dimethoxyindan derivatives: synthesis and assessment of dopaminergic and cardiovascular actions. Journal of Medicinal Chemistry. 25: 858-64. PMID 6125597  1
1982 Grigsby WR, Barfknecht CF, Goodman SM. 6-Aminopenicillanic acid coupled covalently to ε-amino-n-caproic acid agarose as an antiplaque agent Journal of Dental Research. 61: No. 103.  1
1981 Kopp WC, Hiebert CK, Barfknecht CF, Richerson H. In vitro biologic activities of fluoresceinated myramyl dipeptide (MDP) Clinical Research. 29: 688A.  1
1980 Rusterholz DB, Dryer SE, Long JP, Barfknecht CF, Mott J. Sedative and analgesic actions of methoxylated 2-aminotetralins; involvement of alpha 1- and alpha 2-adrenoreceptors. European Journal of Pharmacology. 65: 201-11. PMID 6249622 DOI: 10.1016/0014-2999(80)90393-3  1
1979 Sindelar RD, Rosazza JP, Barfknecht CF. N-demethylation of nicotine and reduction of nicotine-1'-N-oxide by Microsporum gypseum. Applied and Environmental Microbiology. 38: 836-9. PMID 543700  1
1978 Sharabi FM, Long JP, Rusterholz DB, Barfknecht CF. Aminotetralin analogs of methoxamine as potential hypertensive agents. Research Communications in Chemical Pathology and Pharmacology. 19: 37-55. PMID 625593  1
1978 Rusterholz DB, Long JP, Flynn JR, Glyn JR, Barfknecht CF, Lind RW, Johnson AK. Inhibition of apomorphine-induced behaviors by derivatives of 2-amino-1, 2, 3, 4-tetrahydronaphthalene. Archives Internationales De Pharmacodynamie Et De ThéRapie. 232: 246-60. PMID 567044  1
1978 Barfknecht CF, Caputo JF, Tobin MB, Dyer DC, Standirdge RT, Howell HG, Goodwin WR, Partyka RA, Gylys JA, Cavanagh RL. Congeners of DOM: effect of distribution of the evaluation of pharmacologic data. Nida Research Monograph. 16-26. PMID 101880  1
1977 Rusterholz DB, Spratt JL, Long JP, Barfknecht CF. Evaluation of substituted-amphetamine hallucinogens using the cat limb flick model. Communications in Psychopharmacology. 1: 589-92. PMID 608329  1
1977 Rusterholz DB, Barfknecht CF, Clemens JA. Ergoline congeners as potential inhibitors of prolactin release. 3. Derivatives of 3-phenylpiperidine. Journal of Medicinal Chemistry. 20: 85-8. PMID 13217  1
1976 Smith RV, Erhardt PW, Rusterholz DB, Barfknecht CF. NMR study of amphetamines using europium shift reagents. Journal of Pharmaceutical Sciences. 65: 412-7. PMID 1263091 DOI: 10.1002/jps.2600650324  1
1976 Rusterholz DB, Barfknecht CF, Clemens JA. Ergoline congeners as potential inhibitors of prolactin release. 2. Journal of Medicinal Chemistry. 19: 99-102. PMID 1246056  1
1976 Peterson LA, Sharabi FM, Long JP, Taylor CA, Barfknecht CF. The antagonism of nicotine-induced cardiovascular responses by DMAE and DEO analogs. European Journal of Pharmacology. 37: 303-10. PMID 182503 DOI: 10.1016/0022-2828(76)90017-1  0.52
1975 Barfknecht CF, Nichols DE. Correlation of psychotomimetic activity of phenethylamines and amphetamines with 1-octanol-water partition coefficients. Journal of Medicinal Chemistry. 18: 208-10. PMID 1120990  1
1975 Barfknecht CF, Taylor CA. Nonclassical nicotine antagonists. Journal of Medicinal Chemistry. 18: 1161-4. PMID 240939  1
1974 Cheng HC, Long JP, Nichols DE, Barfknecht CF, Rusterholz DB. Effects of rigid amphetamine analogs on vascular strips: studies of 2-aminotetrahydronaphthalene and 2-aminoindan derivatives. Archives Internationales De Pharmacodynamie Et De ThéRapie. 208: 264-73. PMID 4851775  1
1974 Barfknecht CF, Rusterholz DB. Inhibition of prolactin by ergoline congeners. Journal of Medicinal Chemistry. 17: 308-12. PMID 4811226  1
1974 Cheng HC, Long JP, Nichols DE, Barfknecht CF. Effects of psychotomimetics on vascular strips: studies of methoxylated amphetamines and optical isomers of 2,5-dimethoxy-4-methylamphetamine and 2,5-dimethoxy-4-bromoamphetamine. The Journal of Pharmacology and Experimental Therapeutics. 188: 114-23. PMID 4809263  1
1974 Nichols DE, Barfknecht CF, Long JP, Standridge RT, Howell HG, Partyka RA, Dyer DC. Potential psychotomimetics. 2. Rigid analogs of 2,5-dimethoxy-4-methylphenylisopropylamine (DOM, STP). Journal of Medicinal Chemistry. 17: 161-6. PMID 4809251  1
1974 Snyder SH, Unger S, Blatchley R, Barfknecht CF. Stereospecific actions of DOET (2,5-dimethoxy-4-ethylamphetamine) in man. Archives of General Psychiatry. 31: 103-6. PMID 4599412 DOI: 10.1001/archpsyc.1974.01760130079013  1
1974 Cheng HC, Long JP, Nichols DE, Barfknecht CF. Effects of para-methoxyamphetamine (PMA) on the cardiovascular system of the dog. Archives Internationales De Pharmacodynamie Et De ThéRapie. 212: 83-8. PMID 4455128  1
1974 Peterson LA, Taylor C, Barfknecht CF. The anti nicotinic properties of (4,4' biphenylene bis [(2 oxo ethylene) bis (2,2 diethyoxyethyl) dimethylammonium dibromide (DMAE) analogs Federation Proceedings. 33: 1556.  1
1973 Dyer DC, Nichols DE, Rusterholz DB, Barfknecht CF. Comparative effects of stereoisomers of psychotomimetic phenylisopropylamines. Life Sciences. 13: 885-96. PMID 4766265 DOI: 10.1016/0024-3205(73)90079-9  1
1973 Smissman EE, Wachter M, Barfknecht C, Gabbard RB. Reaction of cyclic acid anhydrides with ethyl cyanoacetate. Journal of Pharmaceutical Sciences. 62: 1772-5. PMID 4758073  1
1973 Barfknecht CF, Nichols DE, Rusterholz DB, Long JP, Engelbrecht JA, Beaton JM, Bradley RJ, Dyer DC. Potential psychotomimetics. 2-Amino-1,2,3,4-tetrahydronaphthalene analogs. Journal of Medicinal Chemistry. 16: 804-8. PMID 4725926  1
1973 Cheng HC, Long JP, Barfknecht CF, Nichols DE. Cardiovascular effects of 2, 5-dimethoxy-4-methylamphetamine (DOM, STP). The Journal of Pharmacology and Experimental Therapeutics. 186: 345-54. PMID 4719787  1
1973 Nichols DE, Barfknecht CF, Rusterholz DB, Benington F, Morin RD. Asymmetric synthesis of psychotomimetic phenylisopropylamines. Journal of Medicinal Chemistry. 16: 480-3. PMID 4718460  1
1973 Westby TR, Barfknecht CF. Acridan-4-carboxylic acids and N-aryl-2-amino-3-toluic acids as planar and antiplanar analogs of antiinflammatory N-arylanthranilic acids. Journal of Medicinal Chemistry. 16: 40-3. PMID 4682199  1
1973 Barfknecht CF, Keckler D, Long JP, Greenberg S. The pharmacology of dibenzofuran and terphenyl derivatives of DMAE and hemicholinium-3. Archives Internationales De Pharmacodynamie Et De ThéRapie. 205: 238-37. PMID 4358298  1
1973 Nichols DE, Barfknecht CF. 1 Methyl 3 piperidone and 1 methyl 3 pyrrolidone derivatives from a Dieckmann reaction Journal of Heterocyclic Chemistry. 10: 339-341.  1
1973 Barfknecht CF, Keckler D, Long JP, Greenberg S. The pharmacology of dibenzofuran and terphenyl derivatives of DMAE and hemicholinium 3 Archives Internationales De Pharmacodynamie Et De Therapie. 205: 328-337.  1
1973 Cheng HC, Long JP, Nichols DE, Barfknecht CF. Effects of psychotomimetic amphetamines on vascular tissues Federation Proceedings. 32: I.  1
1972 Engelbrecht JA, Long JP, Nichols DE, Barfknecht CF. Pharmacologic evaluation of 3,4-dimethoxyphenylpropenes and 3,4-dimethoxyphenylpropanediols. Archives Internationales De Pharmacodynamie Et De ThéRapie. 199: 226-44. PMID 5070643  1
1972 Barfknecht CF, Nichols DE. Effects of S-(+)- and R-(-)-3,4,dimethoxyphenylisopropylamines in the rat. Journal of Medicinal Chemistry. 15: 109-10. PMID 5007083  1
1971 Barfknecht CF, Nichols DE. Potential psychotomimetics. Bromomethoxyamphetamines. Journal of Medicinal Chemistry. 14: 370-2. PMID 5553756  1
1971 Antun F, Smythies JR, Benington F, Morin RD, Barfknecht CF, Nichols DE. Native fluorescence and hallucinogenic potency of some amphetamines. Experientia. 27: 62-3. PMID 5549244 DOI: 10.1007/BF02137743  1
1971 Barfknecht CF, Long JP, Benz FW. Aryl-N-methyl-2-pyridiniumketoxime acetylcholinesterase reactivators. Journal of Pharmaceutical Sciences. 60: 138-9. PMID 5548226  1
1971 Barfknecht CF, Smith RV, Nichols DE, Leseney JL, Long JP, Engelbrecht JA. Chemistry and pharmacological evaluation of 1-phenyl-2-propanols and 1-phenyl-2-propanones. Journal of Pharmaceutical Sciences. 60: 799-801. PMID 5125790  1
1971 Barfknecht CF, Benz FW, Long JP. Potential acetylcholinesterase reactivators. p,p-Biphenyl and 1,4-benzene disubstituted oximes. Journal of Medicinal Chemistry. 14: 1003-4. PMID 5115676  1
1970 Barfknecht CF, Miles JM, Leseney JL. 1-(3,4-dimethoxyphenyl)-2-propanol effect on conditioned avoidance response in the rat. Journal of Pharmaceutical Sciences. 59: 1842-4. PMID 5499729  1
1969 Barfknecht CF, Pirch G. 2-Hydroxy-2-phenylethylhydrazine monoamine oxidase inhibitors. Journal of Medicinal Chemistry. 12: 549-50. PMID 5788187  1
1969 Barfknecht CF, Westby TR. Conformationally and configurationally stabilized benzaldoxime. Journal of Pharmaceutical Sciences. 58: 490-1. PMID 5787453  1
1968 Barfknecht CF, Peng HC. Antifertility factors from plants. I. Preliminary extraction and screening. Journal of Pharmaceutical Sciences. 57: 1607-8. PMID 5674402  1
1967 Barfknecht CF. Stereochemical assignments of 1-benzocyclobutenyl ketoximes. Journal of Pharmaceutical Sciences. 56: 1364. PMID 6059465  1
1967 Barfknecht CF, Westby TR. Trifluoromethylbenzaldoximes. Journal of Medicinal Chemistry. 10: 1192-3. PMID 6056064  1
1964 SMISSMAN EE, BARFKNECHT CF. POLAROGRAPHIC ANALYSIS OF SOME SULFONIC ACIDS. Journal of Pharmaceutical Sciences. 53: 1404. PMID 14253605  1
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