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Nigel D. F. Grindley - Publications

Affiliations: 
Molecular Biophysics and Biochemistry Yale University, New Haven, CT 
Area:
DNA Replication and Repair
Website:
http://medicine.yale.edu/mbb/faculty/research/nigel_grindley.profile

105 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Keenholtz RA, Grindley ND, Hatfull GF, Marko JF. Crossover-site sequence and DNA torsional stress control strand interchanges by the Bxb1 site-specific serine recombinase. Nucleic Acids Research. PMID 27550179 DOI: 10.1093/Nar/Gkw724  0.668
2013 Bermek O, Grindley ND, Joyce CM. Prechemistry nucleotide selection checkpoints in the reaction pathway of DNA polymerase I and roles of glu710 and tyr766. Biochemistry. 52: 6258-74. PMID 23937394 DOI: 10.1021/Bi400837K  0.552
2013 Hohlbein J, Aigrain L, Craggs TD, Bermek O, Potapova O, Shoolizadeh P, Grindley ND, Joyce CM, Kapanidis AN. Conformational landscapes of DNA polymerase I and mutator derivatives establish fidelity checkpoints for nucleotide insertion. Nature Communications. 4: 2131. PMID 23831915 DOI: 10.1038/Ncomms3131  0.52
2012 Bai H, Kath JE, Zörgiebel FM, Sun M, Ghosh P, Hatfull GF, Grindley ND, Marko JF. Remote control of DNA-acting enzymes by varying the Brownian dynamics of a distant DNA end. Proceedings of the National Academy of Sciences of the United States of America. 109: 16546-51. PMID 23011800 DOI: 10.1073/Pnas.1203118109  0.781
2012 Bai H, Kath J, Zorgebiel F, Grindley ND, Marko JF. Remote Control of DNA-Acting Enzymes by Molecular Boundary Conditions Biophysical Journal. 102: 70a. DOI: 10.1016/J.Bpj.2011.11.412  0.421
2011 Bai H, Sun M, Ghosh P, Hatfull GF, Grindley ND, Marko JF. Single-molecule analysis reveals the molecular bearing mechanism of DNA strand exchange by a serine recombinase. Proceedings of the National Academy of Sciences of the United States of America. 108: 7419-24. PMID 21502527 DOI: 10.1073/Pnas.1018436108  0.811
2011 Bermek O, Grindley ND, Joyce CM. Distinct roles of the active-site Mg2+ ligands, Asp882 and Asp705, of DNA polymerase I (Klenow fragment) during the prechemistry conformational transitions. The Journal of Biological Chemistry. 286: 3755-66. PMID 21084297 DOI: 10.1074/Jbc.M110.167593  0.518
2011 Hohlbein J, Joyce CM, Shoolizadeh P, Evans G, Potapova O, Bermek O, Duchillumigusin D, Grindley ND, Kapanidis AN. Novel Conformational States in Mutator DNA Polymerases Observed Using Single-Molecule FRET Biophysical Journal. 100: 240a-241a. DOI: 10.1016/J.Bpj.2010.12.1532  0.542
2010 Santoso Y, Joyce CM, Potapova O, Le Reste L, Hohlbein J, Torella JP, Grindley ND, Kapanidis AN. Conformational transitions in DNA polymerase I revealed by single-molecule FRET. Proceedings of the National Academy of Sciences of the United States of America. 107: 715-20. PMID 20080740 DOI: 10.1073/Pnas.0910909107  0.513
2010 Torella JP, Santoso Y, Holden SJ, Hohlbein J, Joyce CM, Potapova O, Grindley ND, Kapanidis AN. Separating Static and Dynamic Heterogeneity in Single-Molecule FRET Experiments with Burst Variance Analysis (BVA) Biophysical Journal. 98: 591a. DOI: 10.1016/J.Bpj.2009.12.3213  0.323
2010 Santoso Y, Joyce CM, Potapova O, Le Reste L, Hohlbein J, Torella JP, Grindley ND, Kapanidis AN. Conformational Changes in DNA Polymerase I Revealed by Single-Molecule FRET Biophysical Journal. 98: 436a-437a. DOI: 10.1016/J.Bpj.2009.12.2370  0.537
2009 Sun M, Bai H, Grindley ND, Marko JF. Single-molecule Study of Site-specific DNA Recombination by γδ Resolvase Biophysical Journal. 96: 59a. DOI: 10.1016/J.Bpj.2008.12.204  0.512
2008 Gehman JD, Cocco MJ, Grindley ND. Chemical shift mapping of gammadelta resolvase dimer and activated tetramer: mechanistic implications for DNA strand exchange. Biochimica Et Biophysica Acta. 1784: 2086-92. PMID 18840551 DOI: 10.1016/J.Bbapap.2008.08.023  0.492
2008 Joyce CM, Potapova O, Delucia AM, Huang X, Basu VP, Grindley ND. Fingers-closing and other rapid conformational changes in DNA polymerase I (Klenow fragment) and their role in nucleotide selectivity. Biochemistry. 47: 6103-16. PMID 18473481 DOI: 10.1021/Bi7021848  0.817
2007 DeLucia AM, Grindley ND, Joyce CM. Conformational changes during normal and error-prone incorporation of nucleotides by a Y-family DNA polymerase detected by 2-aminopurine fluorescence. Biochemistry. 46: 10790-803. PMID 17725324 DOI: 10.1021/Bi7006756  0.836
2006 DeLucia AM, Chaudhuri S, Potapova O, Grindley ND, Joyce CM. The properties of steric gate mutants reveal different constraints within the active sites of Y-family and A-family DNA polymerases. The Journal of Biological Chemistry. 281: 27286-91. PMID 16831866 DOI: 10.1074/Jbc.M604393200  0.824
2006 Kamtekar S, Ho RS, Cocco MJ, Li W, Wenwieser SV, Boocock MR, Grindley ND, Steitz TA. Implications of structures of synaptic tetramers of gamma delta resolvase for the mechanism of recombination. Proceedings of the National Academy of Sciences of the United States of America. 103: 10642-7. PMID 16807292 DOI: 10.1073/Pnas.0604062103  0.624
2006 Grindley ND, Whiteson KL, Rice PA. Mechanisms of site-specific recombination. Annual Review of Biochemistry. 75: 567-605. PMID 16756503 DOI: 10.1146/Annurev.Biochem.73.011303.073908  0.578
2006 Potapova O, Chan C, DeLucia AM, Helquist SA, Kool ET, Grindley ND, Joyce CM. DNA polymerase catalysis in the absence of Watson-Crick hydrogen bonds: analysis by single-turnover kinetics. Biochemistry. 45: 890-8. PMID 16411765 DOI: 10.1021/Bi051792I  0.783
2005 Li W, Kamtekar S, Xiong Y, Sarkis GJ, Grindley ND, Steitz TA. Structure of a synaptic gammadelta resolvase tetramer covalently linked to two cleaved DNAs. Science (New York, N.Y.). 309: 1210-5. PMID 15994378 DOI: 10.2210/Pdb1Zr2/Pdb  0.814
2005 Altman S, Bassler BL, Beckwith J, Belfort M, Berg HC, Bloom B, Brenchley JE, Campbell A, Collier RJ, Connell N, Cozzarelli NR, Craig NL, Darst S, Ebright RH, Elledge SJ, ... ... Grindley ND, et al. An open letter to Elias Zerhouni. Science (New York, N.Y.). 307: 1409-10. PMID 15746409 DOI: 10.1126/Science.307.5714.1409C  0.716
2004 Lewis LA, Cylin E, Lee HK, Saby R, Wong W, Grindley ND. The left end of IS2: a compromise between transpositional activity and an essential promoter function that regulates the transposition pathway. Journal of Bacteriology. 186: 858-65. PMID 14729714 DOI: 10.1128/Jb.186.3.858-865.2004  0.339
2003 Leschziner AE, Grindley ND. The architecture of the gammadelta resolvase crossover site synaptic complex revealed by using constrained DNA substrates. Molecular Cell. 12: 775-81. PMID 14527421 DOI: 10.1016/S1097-2765(03)00351-4  0.761
2003 Purohit V, Grindley ND, Joyce CM. Use of 2-aminopurine fluorescence to examine conformational changes during nucleotide incorporation by DNA polymerase I (Klenow fragment). Biochemistry. 42: 10200-11. PMID 12939148 DOI: 10.1021/Bi0341206  0.404
2003 DeLucia AM, Grindley ND, Joyce CM. An error-prone family Y DNA polymerase (DinB homolog from Sulfolobus solfataricus) uses a 'steric gate' residue for discrimination against ribonucleotides. Nucleic Acids Research. 31: 4129-37. PMID 12853630 DOI: 10.1093/Nar/Gkg417  0.831
2003 Turner RM, Grindley ND, Joyce CM. Interaction of DNA polymerase I (Klenow fragment) with the single-stranded template beyond the site of synthesis. Biochemistry. 42: 2373-85. PMID 12600204 DOI: 10.1021/Bi026566C  0.569
2002 Potapova O, Grindley ND, Joyce CM. The mutational specificity of the Dbh lesion bypass polymerase and its implications. The Journal of Biological Chemistry. 277: 28157-66. PMID 12023283 DOI: 10.1074/Jbc.M202607200  0.495
2002 Kirby C, Waring A, Griffin TJ, Falkinham JO, Grindley ND, Derbyshire KM. Cryptic plasmids of Mycobacterium avium: Tn552 to the rescue. Molecular Microbiology. 43: 173-86. PMID 11849545 DOI: 10.1046/J.1365-2958.2002.02729.X  0.441
2002 Minnick DT, Liu L, Grindley ND, Kunkel TA, Joyce CM. Discrimination against purine-pyrimidine mispairs in the polymerase active site of DNA polymerase I: a structural explanation. Proceedings of the National Academy of Sciences of the United States of America. 99: 1194-9. PMID 11830658 DOI: 10.1073/Pnas.032457899  0.532
2001 Lewis LA, Gadura N, Greene M, Saby R, Grindley ND. The basis of asymmetry in IS2 transposition. Molecular Microbiology. 42: 887-901. PMID 11737634 DOI: 10.1046/J.1365-2958.2001.02662.X  0.37
2001 Sarkis GJ, Murley LL, Leschziner AE, Boocock MR, Stark WM, Grindley ND. A model for the gamma delta resolvase synaptic complex. Molecular Cell. 8: 623-31. PMID 11583624 DOI: 10.1016/S1097-2765(01)00334-3  0.679
2001 Xu Y, Potapova O, Leschziner AE, Grindley ND, Joyce CM. Contacts between the 5' nuclease of DNA polymerase I and its DNA substrate. The Journal of Biological Chemistry. 276: 30167-77. PMID 11349126 DOI: 10.1074/Jbc.M100985200  0.789
2001 Colegio OR, Griffin TJ, Grindley ND, Galán JE. In vitro transposition system for efficient generation of random mutants of Campylobacter jejuni. Journal of Bacteriology. 183: 2384-8. PMID 11244083 DOI: 10.1128/Jb.183.7.2384-2388.2001  0.32
2000 Xu Y, Grindley ND, Joyce CM. Coordination between the polymerase and 5'-nuclease components of DNA polymerase I of Escherichia coli. The Journal of Biological Chemistry. 275: 20949-55. PMID 10806216 DOI: 10.1074/Jbc.M909135199  0.592
1999 Griffin TJ, Parsons L, Leschziner AE, DeVost J, Derbyshire KM, Grindley ND. In vitro transposition of Tn552: a tool for DNA sequencing and mutagenesis. Nucleic Acids Research. 27: 3859-65. PMID 10481025 DOI: 10.1093/Nar/27.19.3859  0.732
1999 Arnold PH, Blake DG, Grindley ND, Boocock MR, Stark WM. Mutants of Tn3 resolvase which do not require accessory binding sites for recombination activity. The Embo Journal. 18: 1407-14. PMID 10064606 DOI: 10.1093/Emboj/18.5.1407  0.464
1998 Murley LL, Grindley ND. Architecture of the gamma delta resolvase synaptosome: oriented heterodimers identity interactions essential for synapsis and recombination. Cell. 95: 553-62. PMID 9827807 DOI: 10.1016/S0092-8674(00)81622-0  0.392
1998 Leschziner AE, Griffin TJ, Grindley ND. Tn552 transposase catalyzes concerted strand transfer in vitro. Proceedings of the National Academy of Sciences of the United States of America. 95: 7345-50. PMID 9636151 DOI: 10.1073/Pnas.95.13.7345  0.741
1998 Astatke M, Grindley ND, Joyce CM. How E. coli DNA polymerase I (Klenow fragment) distinguishes between deoxy- and dideoxynucleotides. Journal of Molecular Biology. 278: 147-65. PMID 9571040 DOI: 10.1006/Jmbi.1998.1672  0.46
1998 Astatke M, Ng K, Grindley ND, Joyce CM. A single side chain prevents Escherichia coli DNA polymerase I (Klenow fragment) from incorporating ribonucleotides. Proceedings of the National Academy of Sciences of the United States of America. 95: 3402-7. PMID 9520378 DOI: 10.1073/Pnas.95.7.3402  0.528
1997 Grindley ND. Site-specific recombination: synapsis and strand exchange revealed. Current Biology : Cb. 7: R608-12. PMID 9368738 DOI: 10.1016/S0960-9822(06)00314-9  0.42
1997 Lewis LA, Grindley ND. Two abundant intramolecular transposition products, resulting from reactions initiated at a single end, suggest that IS2 transposes by an unconventional pathway. Molecular Microbiology. 25: 517-29. PMID 9302014 DOI: 10.1046/J.1365-2958.1997.4871848.X  0.424
1997 Xu Y, Derbyshire V, Ng K, Sun XC, Grindley ND, Joyce CM. Biochemical and mutational studies of the 5'-3' exonuclease of DNA polymerase I of Escherichia coli. Journal of Molecular Biology. 268: 284-302. PMID 9159471 DOI: 10.1006/Jmbi.1997.0967  0.551
1996 Derbyshire KM, Grindley ND. Cis preference of the IS903 transposase is mediated by a combination of transposase instability and inefficient translation. Molecular Microbiology. 21: 1261-72. PMID 8898394 DOI: 10.1111/J.1365-2958.1996.Tb02587.X  0.34
1995 Grindley ND, Leschziner AE. DNA transposition: from a black box to a color monitor. Cell. 83: 1063-6. PMID 8548793 DOI: 10.1016/0092-8674(95)90132-9  0.712
1995 Astatke M, Grindley ND, Joyce CM. Deoxynucleoside triphosphate and pyrophosphate binding sites in the catalytically competent ternary complex for the polymerase reaction catalyzed by DNA polymerase I (Klenow fragment). The Journal of Biological Chemistry. 270: 1945-54. PMID 7829532 DOI: 10.1074/Jbc.270.4.1945  0.531
1995 May EW, Grindley ND. A functional analysis of the inverted repeat of the gamma delta transposable element. Journal of Molecular Biology. 247: 578-87. PMID 7723015 DOI: 10.1006/jmbi.1995.0164  0.305
1995 Leschziner AE, Boocock MR, Grindley ND. The tyrosine-6 hydroxyl of gamma delta resolvase is not required for the DNA cleavage and rejoining reactions. Molecular Microbiology. 15: 865-70. PMID 7596288 DOI: 10.1111/J.1365-2958.1995.Tb02356.X  0.785
1995 Boocock MR, Zhu X, Grindley ND. Catalytic residues of gamma delta resolvase act in cis. The Embo Journal. 14: 5129-40. PMID 7588641 DOI: 10.1002/J.1460-2075.1995.Tb00195.X  0.535
1995 May EW, Grindley ND. A functional analysis of the inverted repeat of the γδ transposable element Journal of Molecular Biology. 247: 578-587. DOI: 10.1016/S0022-2836(05)80139-1  0.412
1993 Hughes RE, Rice PA, Steitz TA, Grindley ND. Protein-protein interactions directing resolvase site-specific recombination: a structure-function analysis. The Embo Journal. 12: 1447-58. PMID 8385604 DOI: 10.1002/J.1460-2075.1993.Tb05788.X  0.686
1993 Mazzarelli JM, Ermácora MR, Fox RO, Grindley ND. Mapping interactions between the catalytic domain of resolvase and its DNA substrate using cysteine-coupled EDTA-iron. Biochemistry. 32: 2979-86. PMID 8384484 DOI: 10.1021/Bi00063A008  0.563
1993 Grindley ND. Analysis of a nucleoprotein complex: the synaptosome of gamma delta resolvase. Science (New York, N.Y.). 262: 738-40. PMID 8235593 DOI: 10.1126/Science.8235593  0.551
1992 Polesky AH, Dahlberg ME, Benkovic SJ, Grindley ND, Joyce CM. Side chains involved in catalysis of the polymerase reaction of DNA polymerase I from Escherichia coli. The Journal of Biological Chemistry. 267: 8417-28. PMID 1569092  0.395
1992 Joyce CM, Sun XC, Grindley ND. Reactions at the polymerase active site that contribute to the fidelity of Escherichia coli DNA polymerase I (Klenow fragment). The Journal of Biological Chemistry. 267: 24485-500. PMID 1447195  0.482
1992 Derbyshire KM, Grindley ND. Binding of the IS903 transposase to its inverted repeat in vitro. The Embo Journal. 11: 3449-55. PMID 1324175 DOI: 10.1002/J.1460-2075.1992.Tb05424.X  0.398
1991 Derbyshire V, Grindley ND, Joyce CM. The 3'-5' exonuclease of DNA polymerase I of Escherichia coli: contribution of each amino acid at the active site to the reaction. The Embo Journal. 10: 17-24. PMID 1989882 DOI: 10.1002/J.1460-2075.1991.Tb07916.X  0.495
1991 Stark WM, Grindley ND, Hatfull GF, Boocock MR. Resolvase-catalysed reactions between res sites differing in the central dinucleotide of subsite I. The Embo Journal. 10: 3541-8. PMID 1655422  0.57
1990 Polesky AH, Steitz TA, Grindley ND, Joyce CM. Identification of residues critical for the polymerase activity of the Klenow fragment of DNA polymerase I from Escherichia coli. The Journal of Biological Chemistry. 265: 14579-91. PMID 2201688  0.475
1990 Hughes RE, Hatfull GF, Rice P, Steitz TA, Grindley ND. Cooperativity mutants of the gamma delta resolvase identify an essential interdimer interaction. Cell. 63: 1331-8. PMID 2175679 DOI: 10.1016/0092-8674(90)90428-H  0.771
1990 Sanderson MR, Freemont PS, Rice PA, Goldman A, Hatfull GF, Grindley ND, Steitz TA. The crystal structure of the catalytic domain of the site-specific recombination enzyme gamma delta resolvase at 2.7 A resolution. Cell. 63: 1323-9. PMID 2175678 DOI: 10.1016/0092-8674(90)90427-G  0.722
1990 Wiater LA, Grindley ND. Uncoupling of transpositional immunity from gamma delta transposition by a mutation at the end of gamma delta. Journal of Bacteriology. 172: 4959-63. PMID 2168371 DOI: 10.1128/Jb.172.9.4959-4963.1990  0.421
1990 Wiater LA, Grindley ND. Integration host factor increases the transpositional immunity conferred by gamma delta ends. Journal of Bacteriology. 172: 4951-8. PMID 2168370 DOI: 10.1128/Jb.172.9.4951-4958.1990  0.355
1990 Dröge P, Hatfull GF, Grindley ND, Cozzarelli NR. The two functional domains of gamma delta resolvase act on the same recombination site: implications for the mechanism of strand exchange. Proceedings of the National Academy of Sciences of the United States of America. 87: 5336-40. PMID 2164677 DOI: 10.1073/Pnas.87.14.5336  0.663
1990 Derbyshire KM, Kramer M, Grindley ND. Role of instability in the cis action of the insertion sequence IS903 transposase. Proceedings of the National Academy of Sciences of the United States of America. 87: 4048-52. PMID 2161528 DOI: 10.1073/Pnas.87.11.4048  0.39
1990 Rimphanitchayakit V, Grindley ND. Saturation mutagenesis of the DNA site bound by the small carboxy-terminal domain of gamma delta resolvase. The Embo Journal. 9: 719-25. PMID 2155779 DOI: 10.1002/J.1460-2075.1990.Tb08165.X  0.481
1989 Hatfull GF, Sanderson MR, Freemont PS, Raccuia PR, Grindley ND, Steitz TA. Preparation of heavy-atom derivatives using site-directed mutagenesis. Introduction of cysteine residues into gamma delta resolvase. Journal of Molecular Biology. 208: 661-7. PMID 2553982 DOI: 10.1016/0022-2836(89)90156-3  0.657
1989 Rimphanitchayakit V, Hatfull GF, Grindley ND. The 43 residue DNA binding domain of gamma delta resolvase binds adjacent major and minor grooves of DNA. Nucleic Acids Research. 17: 1035-50. PMID 2537948 DOI: 10.1093/Nar/17.3.1035  0.664
1988 Salvo JJ, Grindley ND. The gamma delta resolvase bends the res site into a recombinogenic complex. The Embo Journal. 7: 3609-16. PMID 2850169 DOI: 10.1002/J.1460-2075.1988.Tb03239.X  0.51
1988 Wiater LA, Grindley ND. Gamma delta transposase and integration host factor bind cooperatively at both ends of gamma delta. The Embo Journal. 7: 1907-11. PMID 2844529 DOI: 10.1002/J.1460-2075.1988.Tb03024.X  0.462
1988 Falvey E, Hatfull GF, Grindley ND. Uncoupling of the recombination and topoisomerase activities of the gamma delta resolvase by a mutation at the crossover point. Nature. 332: 861-3. PMID 2833710 DOI: 10.1038/332861A0  0.685
1987 Falvey E, Grindley ND. Contacts between gamma delta resolvase and the gamma delta res site. The Embo Journal. 6: 815-21. PMID 3034611  0.322
1987 Hatfull GF, Noble SM, Grindley ND. The gamma delta resolvase induces an unusual DNA structure at the recombinational crossover point. Cell. 49: 103-10. PMID 3030563 DOI: 10.1016/0092-8674(87)90760-4  0.67
1987 Salvo JJ, Grindley ND. Helical phasing between DNA bends and the determination of bend direction. Nucleic Acids Research. 15: 9771-9. PMID 2827112 DOI: 10.1093/Nar/15.23.9771  0.558
1987 Derbyshire KM, Hwang L, Grindley ND. Genetic analysis of the interaction of the insertion sequence IS903 transposase with its terminal inverted repeats. Proceedings of the National Academy of Sciences of the United States of America. 84: 8049-53. PMID 2825175 DOI: 10.1073/Pnas.84.22.8049  0.408
1986 Derbyshire KM, Salvo JJ, Grindley ND. A simple and efficient procedure for saturation mutagenesis using mixed oligodeoxynucleotides. Gene. 46: 145-52. PMID 3803923 DOI: 10.1016/0378-1119(86)90398-7  0.432
1986 Derbyshire KM, Grindley ND. Replicative and conservative transposition in bacteria. Cell. 47: 325-7. PMID 3021339 DOI: 10.1016/0092-8674(86)90586-6  0.465
1986 Hatfull GF, Grindley ND. Analysis of gamma delta resolvase mutants in vitro: evidence for an interaction between serine-10 of resolvase and site I of res. Proceedings of the National Academy of Sciences of the United States of America. 83: 5429-33. PMID 3016704 DOI: 10.1073/Pnas.83.15.5429  0.641
1985 Joyce CM, Fujii DM, Laks HS, Hughes CM, Grindley ND. Genetic mapping and DNA sequence analysis of mutations in the polA gene of Escherichia coli. Journal of Molecular Biology. 186: 283-93. PMID 3910840 DOI: 10.1016/0022-2836(85)90105-6  0.542
1985 Grindley ND, Reed RR. Transpositional recombination in prokaryotes. Annual Review of Biochemistry. 54: 863-96. PMID 2992361 DOI: 10.1146/Annurev.Bi.54.070185.004243  0.594
1984 Abdel-Meguid SS, Grindley ND, Templeton NS, Steitz TA. Cleavage of the site-specific recombination protein gamma delta resolvase: the smaller of two fragments binds DNA specifically. Proceedings of the National Academy of Sciences of the United States of America. 81: 2001-5. PMID 6326096 DOI: 10.1073/Pnas.81.7.2001  0.659
1984 Weinert TA, Derbyshire KM, Hughson FM, Grindley ND. Replicative and conservative transpositional recombination of insertion sequences. Cold Spring Harbor Symposia On Quantitative Biology. 49: 251-60. PMID 6099240 DOI: 10.1101/Sqb.1984.049.01.029  0.357
1984 Wells RG, Grindley ND. Analysis of the gamma delta res site. Sites required for site-specific recombination and gene expression. Journal of Molecular Biology. 179: 667-87. PMID 6094833 DOI: 10.1016/0022-2836(84)90161-X  0.362
1984 Newman BJ, Grindley ND. Mutants of the gamma delta resolvase: a genetic analysis of the recombination function. Cell. 38: 463-9. PMID 6088082 DOI: 10.1016/0092-8674(84)90501-4  0.395
1983 Joyce CM, Grindley ND. Construction of a plasmid that overproduces the large proteolytic fragment (Klenow fragment) of DNA polymerase I of Escherichia coli. Proceedings of the National Academy of Sciences of the United States of America. 80: 1830-4. PMID 6340110 DOI: 10.1073/Pnas.80.7.1830  0.503
1983 Weinert TA, Schaus NA, Grindley ND. Insertion sequence duplication in transpositional recombination. Science (New York, N.Y.). 222: 755-65. PMID 6314502 DOI: 10.1126/Science.6314502  0.429
1982 Grindley ND, Lauth MR, Wells RG, Wityk RJ, Salvo JJ, Reed RR. Transposon-mediated site-specific recombination: identification of three binding sites for resolvase at the res sites of gamma delta and Tn3. Cell. 30: 19-27. PMID 6290077 DOI: 10.1016/0092-8674(82)90007-1  0.655
1982 Joyce CM, Kelley WS, Grindley ND. Nucleotide sequence of the Escherichia coli polA gene and primary structure of DNA polymerase I. The Journal of Biological Chemistry. 257: 1958-64. PMID 6276402  0.775
1981 Reed RR, Grindley ND. Transposon-mediated site-specific recombination in vitro: DNA cleavage and protein-DNA linkage at the recombination site. Cell. 25: 721-8. PMID 6269756 DOI: 10.1016/0092-8674(81)90179-3  0.74
1980 Grindley ND, Joyce CM. Genetic and DNA sequence analysis of the kanamycin resistance transposon Tn903. Proceedings of the National Academy of Sciences of the United States of America. 77: 7176-80. PMID 6261245  0.404
1979 Reed RR, Young RA, Steitz JA, Grindley ND, Guyer MS. Transposition of the Escherichia coli insertion element gamma generates a five-base-pair repeat. Proceedings of the National Academy of Sciences of the United States of America. 76: 4882-6. PMID 388421 DOI: 10.1073/Pnas.76.10.4882  0.743
1978 Grindley ND. IS1 insertion generates duplication of a nine base pair sequence at its target site. Cell. 13: 419-26. PMID 350412 DOI: 10.1016/0092-8674(78)90316-1  0.42
1976 Kelley WS, Grindley ND. Mapping of the polA locus of Escherichia coli K12: orientation in the amino- and carboxy-termini of the cistron. Molecular & General Genetics : Mgg. 147: 307-14. PMID 787765 DOI: 10.1007/Bf00582882  0.733
1976 Grindley ND, Kelley WS. Effects of different alleles of the E. coli K12 pol A gene on the replication of non-transferring plasmids. Molecular & General Genetics : Mgg. 143: 311-8. PMID 765763 DOI: 10.1007/Bf00269409  0.745
1976 Kelly WS, Grindley ND. polA6, A mutation affecting the DNA binding capacity of DNA polymerase I. Nucleic Acids Research. 3: 2971-84. PMID 12497  0.422
1973 Smith HR, Humphreys GO, Grindley ND, Grindley JN, Anderson ES. Molecular studies of an fi+ plasmid from strains of Salmonella typhimurium. Molecular & General Genetics : Mgg. 126: 143-51. PMID 4591377 DOI: 10.1007/Bf00330988  0.483
1973 Grindley ND, Humphreys GO, Anderson ES. Molecular studies of R factor compatibility groups. Journal of Bacteriology. 115: 387-98. PMID 4577745  0.51
1973 Grindley ND, Grindley JN, Smith HR, Anderson ES. Characterisation of derepressed mutants of an F-like R factor. Molecular & General Genetics : Mgg. 120: 27-34. PMID 4346770 DOI: 10.1007/BF00332982  0.461
1973 Smith HR, Grindley ND, Humphreys GO, Anderson ES. Interactions of group H resistance factors with the F factor. Journal of Bacteriology. 115: 623-8. PMID 4269378  0.485
1972 Humphreys GO, Grindley ND, Anderson ES. DNA--protein complexes of delta-mediated transfer systems. Biochimica Et Biophysica Acta. 287: 355-60. PMID 4609474 DOI: 10.1016/0005-2787(72)90385-1  0.591
1972 Grindley ND, Grindley JN, Anderson ES. R factor compatibility groups. Molecular & General Genetics : Mgg. 119: 287-97. PMID 4567804 DOI: 10.1007/BF00272087  0.424
1971 Grindley ND, Anderson ES, Smith HR, Grindley JN. The effects of Salmonella typhimurium on derepressed mutants of F-like factors. Genetical Research. 17: 89-93. PMID 4933323  0.469
1970 Smith HR, Grindley JN, Grindley ND, Anderson ES. Derepression of F-lac in Salmonella typhimurium by a determinant for kanamycin resistance. Genetical Research. 16: 349-53. PMID 4934054  0.44
1970 Grindley JN, Grindley ND, Anderson ES. Acridine treatment of F+ and Hfr strains of Escherichia coli K12 carrying a neomycin-kanamycin resistance determinant. Genetical Research. 15: 327-34. PMID 4920243  0.453
1969 Anderson ES, Mayhew JN, Grindley ND. Transfer of a neomycin-kanamycin resistance determinant by the F factor of Escherichia coli K12. Nature. 222: 349-51. PMID 4889488 DOI: 10.1038/222349a0  0.464
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