Jean-Louis Mergny - Publications

Affiliations: 
IECB University of Bordeuax 

279 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Bhatt U, Cucchiarini A, Luo Y, Evans CW, Mergny JL, Iyer KS, Smith NM. Preferential formation of Z-RNA over intercalated motifs in long noncoding RNA. Genome Research. PMID 38355305 DOI: 10.1101/gr.278236.123  0.363
2023 Guillon J, Le Borgne M, Milano V, Guédin-Beaurepaire A, Moreau S, Pinaud N, Ronga L, Savrimoutou S, Albenque-Rubio S, Marchivie M, Kalout H, Walker C, Chevallier L, Buré C, Largy E, ... ... Mergny JL, et al. New 2,4-bis[(substituted-aminomethyl)phenyl]phenylquinazoline and 2,4-bis[(substituted-aminomethyl)phenyl]phenylquinoline Derivatives: Synthesis and Biological Evaluation as Novel Anticancer Agents by Targeting G-Quadruplex. Pharmaceuticals (Basel, Switzerland). 17. PMID 38256866 DOI: 10.3390/ph17010030  0.405
2023 Gajarsky M, Stadlbauer P, Sponer J, Cucchiarini A, Dobrovolna M, Brazda V, Mergny JL, Trantirek L, Lenarcic Zivkovic M. DNA Quadruplex Structure with a Unique Cation Dependency. Angewandte Chemie (International Ed. in English). e202313226. PMID 38143239 DOI: 10.1002/anie.202313226  0.424
2023 Fazelifar P, Cucchiarini A, Khoshbin Z, Mergny JL, Kazemi Noureini S. Strong and selective interactions of palmatine with G-rich sequences in TRF2 promoter; experimental and computational studies. Journal of Biomolecular Structure & Dynamics. 1-15. PMID 38100552 DOI: 10.1080/07391102.2023.2292793  0.426
2023 Dobrovodsky D, Danhel A, Renciuk D, Mergny JL, Fojta M. N-methyl mesoporphyrin IX (NMM) as electrochemical probe for detection of guanine quadruplexes. Bioelectrochemistry (Amsterdam, Netherlands). 156: 108611. PMID 37995502 DOI: 10.1016/j.bioelechem.2023.108611  0.383
2023 Luo Y, Živković ML, Wang J, Ryneš J, Foldynová-Trantírková S, Trantírek L, Verga D, Mergny JL. A sodium/potassium switch for G4-prone G/C-rich sequences. Nucleic Acids Research. PMID 37986223 DOI: 10.1093/nar/gkad1073  0.398
2023 De Rache A, Marquevielle J, Bouaziz S, Vialet B, Andreola ML, Mergny JL, Amrane S. Structure of a DNA G-quadruplex that modulates SP1 binding sites architecture in HIV-1 promoter. Journal of Molecular Biology. 168359. PMID 37952768 DOI: 10.1016/j.jmb.2023.168359  0.393
2023 Saad M, Zhang R, Cucchiarini A, Mehawej C, Mergny JL, Mroueh M, Faour WH. G-quadruplex forming sequences in the genes coding for cytochrome P450 enzymes and their potential roles in drug metabolism. Biochimie. PMID 37660977 DOI: 10.1016/j.biochi.2023.08.014  0.353
2023 Esnault C, Magat T, Zine El Aabidine A, Garcia-Oliver E, Cucchiarini A, Bouchouika S, Lleres D, Goerke L, Luo Y, Verga D, Lacroix L, Feil R, Spicuglia S, Mergny JL, Andrau JC. G4access identifies G-quadruplexes and their associations with open chromatin and imprinting control regions. Nature Genetics. PMID 37400615 DOI: 10.1038/s41588-023-01437-4  0.8
2023 Zhang R, Shu H, Wang Y, Tao T, Tu J, Wang C, Mergny JL, Sun X. G-quadruplex structures are key modulators of somatic structural variants in cancers. Cancer Research. PMID 36791413 DOI: 10.1158/0008-5472.CAN-22-3089  0.37
2023 Ferret L, Alvarez-Valadez K, Rivière J, Muller A, Bohálová N, Yu L, Guittat L, Brázda V, Kroemer G, Mergny JL, Djavaheri-Mergny M. G-quadruplex ligands as potent regulators of lysosomes. Autophagy. 1-15. PMID 36740766 DOI: 10.1080/15548627.2023.2170071  0.405
2022 Luo Y, Granzhan A, Marquevielle J, Cucchiarini A, Lacroix L, Amrane S, Verga D, Mergny JL. Guidelines for G-quadruplexes: I. In vitro characterization. Biochimie. PMID 36596406 DOI: 10.1016/j.biochi.2022.12.019  0.809
2022 Amrane S, Jaubert C, Bedrat A, Rundstadler T, Recordon-Pinson P, Aknin C, Guédin A, De Rache A, Bartolucci L, Diene I, Lemoine F, Gascuel O, Pratviel G, Mergny JL, Andreola ML. Deciphering RNA G-quadruplex function during the early steps of HIV-1 infection. Nucleic Acids Research. 50: 12328-12343. PMID 36453997 DOI: 10.1093/nar/gkac1030  0.33
2022 Moreira D, Leitão D, Lopes-Nunes J, Santos T, Figueiredo J, Miranda A, Alexandre D, Tomaz C, Mergny JL, Cruz C. G-Quadruplex Aptamer-Ligand Characterization. Molecules (Basel, Switzerland). 27. PMID 36296374 DOI: 10.3390/molecules27206781  0.365
2022 Figueiredo J, Carreira-Barral I, Quesada R, Mergny JL, Cruz C. Synthesis and evaluation of 2,9-disubstituted-1,10-phenanthroline derivatives as G-quadruplex binders. Bioorganic & Medicinal Chemistry. 73: 116971. PMID 36208542 DOI: 10.1016/j.bmc.2022.116971  0.467
2022 Dobrovolná M, Bohálová N, Peška V, Wang J, Luo Y, Bartas M, Volná A, Mergny JL, Brázda V. The Newly Sequenced Genome of Is Replete with Potential G-Quadruplex-Forming Sequences-Implications for Evolution and Biological Regulation. International Journal of Molecular Sciences. 23. PMID 35955617 DOI: 10.3390/ijms23158482  0.339
2022 Marquevielle J, De Rache A, Vialet B, Morvan E, Mergny JL, Amrane S. G-quadruplex structure of the C. elegans telomeric repeat: a two tetrads basket type conformation stabilized by a non-canonical C-T base-pair. Nucleic Acids Research. PMID 35736226 DOI: 10.1093/nar/gkac523  0.363
2022 Luo Y, Verga D, Mergny JL. Iso-FRET: an isothermal competition assay to analyze quadruplex formation in vitro. Nucleic Acids Research. PMID 35670668 DOI: 10.1093/nar/gkac465  0.408
2022 Santos T, Lopes-Nunes J, Alexandre D, Miranda A, Figueiredo J, Silva MS, Mergny JL, Cruz C. Stabilization of a DNA aptamer by ligand binding. Biochimie. 200: 8-18. PMID 35550917 DOI: 10.1016/j.biochi.2022.05.002  0.367
2022 Mao X, He F, Qiu D, Wei S, Luo R, Chen Y, Zhang X, Lei J, Monchaud D, Mergny JL, Ju H, Zhou J. Efficient Biocatalytic System for Biosensing by Combining Metal-Organic Framework (MOF)-Based Nanozymes and G-Quadruplex (G4)-DNAzymes. Analytical Chemistry. PMID 35549161 DOI: 10.1021/acs.analchem.2c00600  0.31
2022 Cantara A, Luo Y, Dobrovolná M, Bohalova N, Fojta M, Verga D, Guittat L, Cucchiarini A, Savrimoutou S, Häberli C, Guillon J, Keiser J, Brázda V, Mergny JL. G-quadruplexes in helminth parasites. Nucleic Acids Research. 50: 2719-2735. PMID 35234933 DOI: 10.1093/nar/gkac129  0.361
2022 Chen Y, Qiu D, Zhang X, Liu Y, Cheng M, Lei J, Mergny JL, Ju H, Zhou J. Highly Sensitive Biosensing Applications of a Magnetically Immobilizable Covalent G-Quadruplex-Hemin DNAzyme Catalytic System. Analytical Chemistry. PMID 35050586 DOI: 10.1021/acs.analchem.1c04842  0.32
2021 Ferino A, Marquevielle J, Choudhary H, Cinque G, Robert C, Bourdoncle A, Picco R, Mergny JL, Salgado GF, Xodo LE. hnRNPA1/UP1 Unfolds G-Quadruplexes and Feeds a Regulatory Axis Controlling Gene Expression. Acs Omega. 6: 34092-34106. PMID 34926957 DOI: 10.1021/acsomega.1c05538  0.352
2021 Bohálová N, Mergny JL, Brázda V. Novel G-quadruplex prone sequences emerge in the complete assembly of the human X chromosome. Biochimie. PMID 34508825 DOI: 10.1016/j.biochi.2021.09.004  0.304
2021 Chen J, Cheng M, Salgado GF, Stadlbauer P, Zhang X, Amrane S, Guédin A, He F, Šponer J, Ju H, Mergny JL, Zhou J. The beginning and the end: flanking nucleotides induce a parallel G-quadruplex topology. Nucleic Acids Research. PMID 34379785 DOI: 10.1093/nar/gkab681  0.455
2021 Bhatt U, Kretzmann AL, Guédin A, Ou A, Kobelke S, Bond CS, Evans CW, Hurley LH, Mergny JL, Iyer KS, Fox AH, Smith NM. The role of G-Quadruplex DNA in Paraspeckle formation in cancer. Biochimie. PMID 34329720 DOI: 10.1016/j.biochi.2021.07.008  0.348
2021 Lavigne M, Helynck O, Rigolet P, Boudria-Souilah R, Nowakowski M, Baron B, Brülé S, Hoos S, Raynal B, Guittat L, Beauvineau C, Petres S, Granzhan A, Guillon J, Pratviel G, ... ... Mergny JL, et al. SARS-CoV-2 Nsp3 unique domain SUD interacts with guanine quadruplexes and G4-ligands inhibit this interaction. Nucleic Acids Research. PMID 34232992 DOI: 10.1093/nar/gkab571  0.373
2021 Kejnovská I, Stadlbauer P, Trantírek L, Renčiuk D, Gajarský M, Krafčík D, Palacký J, Bednářová K, Šponer J, Mergny JL, Vorlíčková M. G-Quadruplex formation by DNA sequences deficient in guanines: Two tetrad parallel quadruplexes do not fold intramolecularly. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 34145655 DOI: 10.1002/chem.202100895  0.43
2021 Abiri A, Lavigne M, Rezaei M, Nikzad S, Zare P, Mergny JL, Rahimi HR. Unlocking G-Quadruplexes as Antiviral Targets. Pharmacological Reviews. 73: 897-923. PMID 34045305 DOI: 10.1124/pharmrev.120.000230  0.405
2021 Cheng M, Chen J, Ju H, Zhou J, Mergny JL. Drivers of i-DNA Formation in a Variety of Environments Revealed by Four-Dimensional UV Melting and Annealing. Journal of the American Chemical Society. PMID 33988990 DOI: 10.1021/jacs.1c02209  0.312
2021 Guillon J, Denevault-Sabourin C, Chevret E, Brachet-Botineau M, Milano V, Guédin-Beaurepaire A, Moreau S, Ronga L, Savrimoutou S, Rubio S, Ferrer J, Lamarche J, Mergny JL, Viaud-Massuard MC, Ranz M, et al. Design, synthesis, and antiproliferative effect of 2,9-bis[4-(pyridinylalkylaminomethyl)phenyl]-1,10-phenanthroline derivatives on human leukemic cells by targeting G-quadruplex. Archiv Der Pharmazie. e2000450. PMID 33852185 DOI: 10.1002/ardp.202000450  0.421
2021 Iaccarino N, Cheng M, Qiu D, Pagano B, Amato J, Di Porzio A, Zhou J, Randazzo A, Mergny JL. Effects of sequence and base composition on the CD and TDS profiles of i-DNA. Angewandte Chemie (International Ed. in English). PMID 33617090 DOI: 10.1002/anie.202016822  0.341
2021 Cheng M, Qiu D, Tamon L, Ištvánková E, Víšková P, Amrane S, Guédin A, Chen J, Lacroix L, Ju H, Trantírek L, Sahakyan AB, Zhou J, Mergny JL. Thermal and pH stabilities of i-DNA: confronting in vitro experiments with models and in-cell NMR data. Angewandte Chemie (International Ed. in English). PMID 33605024 DOI: 10.1002/anie.202016801  0.795
2021 Busto N, García-Calvo J, Cuevas JV, Herrera A, Mergny JL, Pons S, Torroba T, García B. Influence of core extension and side chain nature in targeting G-quadruplex structures with perylene monoimide derivatives. Bioorganic Chemistry. 108: 104660. PMID 33550073 DOI: 10.1016/j.bioorg.2021.104660  0.339
2021 Stadlbauer P, Islam B, Otyepka M, Chen J, Monchaud D, Zhou J, Mergny JL, Šponer J. Insights into G-Quadruplex-Hemin Dynamics Using Atomistic Simulations: Implications for Reactivity and Folding. Journal of Chemical Theory and Computation. PMID 33533244 DOI: 10.1021/acs.jctc.0c01176  0.365
2021 Figueiredo J, Miranda A, Lopes-Nunes J, Carvalho J, Alexandre D, Valente S, Mergny JL, Cruz C. Targeting Nucleolin By RNA G-Quadruplex-Forming Motif. Biochemical Pharmacology. 114418. PMID 33460627 DOI: 10.1016/j.bcp.2021.114418  0.378
2021 Birkedal V, Aznauryan M, Noer SL, Pedersen CW, Mergny JL, Teulade-Fichou MP. Ligand binding to dynamically populated G-quadruplex DNA. Chembiochem : a European Journal of Chemical Biology. PMID 33450114 DOI: 10.1002/cbic.202000792  0.412
2020 Luo Y, Granzhan A, Verga D, Mergny JL. FRET-MC: A fluorescence melting competition assay for studying G4 structures in vitro. Biopolymers. ebip23415. PMID 33368198 DOI: 10.1002/bip.23415  0.435
2020 Carvalho J, Lopes-Nunes J, Paula Cabral Campello M, Paulo A, Milici J, Meyers C, Mergny JL, Salgado GF, Queiroz JA, Cruz C. Human Papillomavirus G-Rich Regions as Potential Antiviral Drug Targets. Nucleic Acid Therapeutics. PMID 33121376 DOI: 10.1089/nat.2020.0869  0.313
2020 Brázda V, Luo Y, Bartas M, Kaura P, Porubiaková O, Šťastný J, Pečinka P, Verga D, Da Cunha V, Takahashi TS, Forterre P, Myllykallio H, Fojta M, Mergny JL. G-Quadruplexes in the Archaea Domain. Biomolecules. 10. PMID 32967357 DOI: 10.3390/biom10091349  0.431
2020 Grover J, Trujillo C, Saad M, Emandi G, Stipaničev N, Bernhard SSR, Guédin A, Mergny JL, Senge MO, Rozas I. Dual-binding conjugates of diaromatic guanidines and porphyrins for recognition of G-quadruplexes. Organic & Biomolecular Chemistry. PMID 32648871 DOI: 10.1039/D0Ob01264E  0.45
2020 Gazanion E, Lacroix L, Alberti P, Gurung P, Wein S, Cheng M, Mergny JL, Gomes AR, Lopez-Rubio JJ. Genome wide distribution of G-quadruplexes and their impact on gene expression in malaria parasites. Plos Genetics. 16: e1008917. PMID 32628663 DOI: 10.1371/journal.pgen.1008917  0.779
2020 Beauvarlet J, Nath Das R, Alvarez-Valadez K, Martins I, Muller A, Darbo E, Richard E, Soubeyran P, Kroemer G, Guillon J, Mergny JL, Djavaheri-Mergny M. Triarylpyridine Compounds and Chloroquine Act in Concert to Trigger Lysosomal Membrane Permeabilization and Cell Death in Cancer Cells. Cancers. 12. PMID 32570977 DOI: 10.3390/Cancers12061621  0.332
2020 Prorok P, Artufel M, Aze A, Coulombe P, Peiffer I, Lacroix L, Guédin A, Mergny JL, Damaschke J, Schepers A, Cayrou C, Teulade-Fichou MP, Ballester B, Méchali M. Author Correction: Involvement of G-quadruplex regions in mammalian replication origin activity. Nature Communications. 11: 3058. PMID 32528032 DOI: 10.1038/S41467-020-16122-X  0.771
2020 Školáková P, Badri Z, Foldynová-Trantírková S, Ryneš J, Šponer J, Fojtová M, Fajkus J, Marek R, Vorlíčková M, Mergny JL, Trantírek L. Composite 5-methylations of cytosines modulate i-motif stability in a sequence-specific manner: Implications for DNA nanotechnology and epigenetic regulation of plant telomeric DNA. Biochimica Et Biophysica Acta. General Subjects. 129651. PMID 32492502 DOI: 10.1016/J.Bbagen.2020.129651  0.366
2020 Carvalho J, Mergny JL, Salgado GF, Queiroz JA, Cruz C. G-quadruplex, Friend or Foe: The Role of the G-quartet in Anticancer Strategies. Trends in Molecular Medicine. PMID 32467069 DOI: 10.1016/J.Molmed.2020.05.002  0.459
2020 Marquevielle J, Robert C, Lagrabette O, Wahid M, Bourdoncle A, Xodo LE, Mergny JL, Salgado GF. Structure of two G-quadruplexes in equilibrium in the KRAS promoter. Nucleic Acids Research. PMID 32432667 DOI: 10.1093/Nar/Gkaa387  0.517
2020 Lopes-Nunes J, Carvalho J, Figueiredo J, Ramos CIV, Lourenço LMO, Tomé JPC, Neves MGPMS, Mergny JL, Queiroz JA, Salgado GF, Cruz C. Phthalocyanines for G-quadruplex aptamers binding. Bioorganic Chemistry. 100: 103920. PMID 32413624 DOI: 10.1016/J.Bioorg.2020.103920  0.485
2020 Arévalo-Ruiz M, Amrane S, Rosu F, Belmonte-Reche E, Peñalver P, Mergny JL, Morales JC. Symmetric and dissymmetric carbohydrate-phenyl ditriazole derivatives as DNA G-quadruplex ligands: Synthesis, biophysical studies and antiproliferative activity. Bioorganic Chemistry. 99: 103786. PMID 32229349 DOI: 10.1016/J.Bioorg.2020.103786  0.488
2020 Islam B, Stadlbauer P, Vorlickova M, Mergny JL, Otyepka M, Sponer J. Stability of Two-quartet G-quadruplexes and Their Dimers in Atomistic Simulations. Journal of Chemical Theory and Computation. PMID 32163706 DOI: 10.1021/Acs.Jctc.9B01068  0.392
2020 Brazda V, Kolomaznik J, Mergny JL, Stastny J. G4Killer web application: a tool to design G-quadruplex mutations. Bioinformatics (Oxford, England). PMID 31985802 DOI: 10.1093/Bioinformatics/Btaa057  0.445
2020 Wang J, Cheng M, Chen J, Ju H, Monchaud D, Mergny JL, Zhou J. An oxidatively damaged G-quadruplex/hemin DNAzyme. Chemical Communications (Cambridge, England). PMID 31950946 DOI: 10.1039/C9Cc09237D  0.44
2020 Guillon J, Cohen A, Boudot C, Valle A, Milano V, Das RN, Guédin A, Moreau S, Ronga L, Savrimoutou S, Demourgues M, Reviriego E, Rubio S, Ferriez S, Agnamey P, ... ... Mergny JL, et al. Design, synthesis, and antiprotozoal evaluation of new 2,4-bis[(substituted-aminomethyl)phenyl]quinoline, 1,3-bis[(substituted-aminomethyl)phenyl]isoquinoline and 2,4-bis[(substituted-aminomethyl)phenyl]quinazoline derivatives. Journal of Enzyme Inhibition and Medicinal Chemistry. 35: 432-459. PMID 31899980 DOI: 10.1080/14756366.2019.1706502  0.588
2019 Chen J, Zhang Y, Cheng M, Mergny JL, Lin Q, Zhou J, Ju H. Highly active G-quadruplex/hemin DNAzyme for sensitive colorimetric determination of lead(II). Mikrochimica Acta. 186: 786. PMID 31732805 DOI: 10.1007/S00604-019-3950-3  0.408
2019 Mergny JL. Meeting report: Seventh International Meeting on Quadruplex Nucleic Acids (Changchun, P.R. China, September 6-9, 2019). Biochimie. 168: 100-109. PMID 31704352 DOI: 10.1016/J.Biochi.2019.10.019  0.481
2019 Toshniwal P, Nguyen M, Guédin A, Viola H, Ho D, Kim Y, Bhatt U, Bond C, Hool L, Hurley LH, Mergny JL, Fear M, Wood F, Swaminathan Iyer K, Smith NM. TGF-β-induced fibrotic stress increases G-quadruplex formation in human fibroblasts. Febs Letters. PMID 31677274 DOI: 10.1002/1873-3468.13658  0.459
2019 Krafcikova M, Dzatko S, Caron C, Granzhan A, Fiala R, Loja T, Teulade-Fichou MP, Fessl T, Hansel-Hertsch R, Mergny JL, Foldynová-Trantírková S, Trantirek L. Monitoring DNA-ligand interactions in living human cells using NMR spectroscopy. Journal of the American Chemical Society. PMID 31394899 DOI: 10.1021/Jacs.9B03031  0.33
2019 Prorok P, Artufel M, Aze A, Coulombe P, Peiffer I, Lacroix L, Guédin A, Mergny JL, Damaschke J, Schepers A, Ballester B, Méchali M. Involvement of G-quadruplex regions in mammalian replication origin activity. Nature Communications. 10: 3274. PMID 31332171 DOI: 10.1038/S41467-019-11104-0  0.818
2019 Figueiredo J, Lopes-Nunes J, Carvalho J, Antunes F, Ribeiro M, Campello MPC, Paulo A, Paiva A, Salgado GF, Queiroz JA, Mergny JL, Cruz C. AS1411 derivatives as carriers of G-quadruplex ligands for cervical cancer cells. International Journal of Pharmaceutics. 568: 118511. PMID 31301466 DOI: 10.1016/J.Ijpharm.2019.118511  0.417
2019 Beauvarlet J, Mergny JL, Djavaheri-Mergny M. Activation of the Ataxia Telangiectasia Mutated/Autophagy pathway by a G-quadruplex ligand links senescence with apoptosis. Molecular & Cellular Oncology. 6: 1604047. PMID 31211231 DOI: 10.1080/23723556.2019.1604047  0.419
2019 Carvalho J, Paiva A, Cabral Campello MP, Paulo A, Mergny JL, Salgado GF, Queiroz JA, Cruz C. Aptamer-based Targeted Delivery of a G-quadruplex Ligand in Cervical Cancer Cells. Scientific Reports. 9: 7945. PMID 31138870 DOI: 10.1038/S41598-019-44388-9  0.432
2019 Mishra SK, Shankar U, Jain N, Sikri K, Tyagi JS, Sharma TK, Mergny JL, Kumar A. Characterization of G-Quadruplex Motifs in espB, espK, and cyp51 Genes of Mycobacterium tuberculosis as Potential Drug Targets. Molecular Therapy. Nucleic Acids. 16: 698-706. PMID 31128421 DOI: 10.1016/J.Omtn.2019.04.022  0.435
2019 Jaubert C, Bedrat A, Bartolucci L, Di Primo C, Ventura M, Mergny JL, Amrane S, Andreola ML. Author Correction: RNA synthesis is modulated by G-quadruplex formation in Hepatitis C virus negative RNA strand. Scientific Reports. 9: 7954. PMID 31123285 DOI: 10.1038/S41598-019-43445-7  0.349
2019 Saad M, Guédin A, Amor S, Bedrat A, Tourasse NJ, Fayyad-Kazan H, Pratviel G, Lacroix L, Mergny JL. Mapping and characterization of G-quadruplexes in the genome of the social amoeba Dictyostelium discoideum. Nucleic Acids Research. PMID 30923812 DOI: 10.1093/Nar/Gkz196  0.809
2019 Pipier A, De Rache A, Modeste C, Amrane S, Mothes-Martin E, Stigliani JL, Calsou P, Mergny JL, Pratviel G, Gomez D. G-Quadruplex binding optimization by gold(iii) insertion into the center of a porphyrin. Dalton Transactions (Cambridge, England : 2003). PMID 30860519 DOI: 10.1039/C8Dt04703K  0.479
2019 Beauvarlet J, Bensadoun P, Darbo E, Labrunie G, Rousseau B, Richard E, Draskovic I, Londono-Vallejo A, Dupuy JW, Nath Das R, Guédin A, Robert G, Orange F, Croce S, Valesco V, ... ... Mergny JL, et al. Modulation of the ATM/autophagy pathway by a G-quadruplex ligand tips the balance between senescence and apoptosis in cancer cells. Nucleic Acids Research. PMID 30759257 DOI: 10.1093/Nar/Gkz095  0.348
2019 Brázda V, Kolomazník J, Lýsek J, Bartas M, Fojta M, Štastný J, Mergny JL. G4Hunter web application: a web server for G-quadruplex prediction. Bioinformatics (Oxford, England). PMID 30721922 DOI: 10.1093/Bioinformatics/Btz087  0.442
2019 Lombardo CM, Kumar M V V, Douat C, Rosu F, Mergny JL, Salgado GF, Guichard G. Design and Structure Determination of a Composite Zinc Finger Containing a Nonpeptide Foldamer Helical Domain. Journal of the American Chemical Society. 141: 2516-2525. PMID 30715863 DOI: 10.1021/Jacs.8B12240  0.387
2019 Mergny JL, Sen D. DNA Quadruple Helices in Nanotechnology. Chemical Reviews. PMID 30605316 DOI: 10.1021/Acs.Chemrev.8B00629  0.469
2018 Zuffo M, Stucchi A, Campos-Salinas J, Cabello-Donayre M, Martínez-García M, Belmonte-Reche E, Pérez-Victoria JM, Mergny JL, Freccero M, Morales JC, Doria F. Carbohydrate-naphthalene diimide conjugates as potential antiparasitic drugs: Synthesis, evaluation and structure-activity studies. European Journal of Medicinal Chemistry. 163: 54-66. PMID 30503943 DOI: 10.1016/j.ejmech.2018.11.043  0.374
2018 Petitjean A, Miron CE, Colden Leung MR, Kennedy EI, Wu N, Fleischel O, Mergny JL, Ashraf Khorasani M. Closing the Loop: Triazolylpyridine Coordination Drives the Self-Assembly of Metallomacrocycles with Tunable Topologies for Small Molecule and Guanine Quadruplex Recognition. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 30239042 DOI: 10.1002/Chem.201803731  0.318
2018 Cheng M, Cheng Y, Hao J, Jia G, Zhou J, Mergny JL, Li C. Loop permutation affects the topology and stability of G-quadruplexes. Nucleic Acids Research. PMID 30184167 DOI: 10.1093/Nar/Gky757  0.517
2018 Havrila M, Stadlbauer P, Kührová P, Banáš P, Mergny JL, Otyepka M, Šponer J. Structural dynamics of propeller loop: towards folding of RNA G-quadruplex. Nucleic Acids Research. PMID 30165550 DOI: 10.1093/Nar/Gky712  0.457
2018 Ou A, Guédin A, Skelton BW, Amrane S, Evans CW, Norret M, Iyer KS, Mergny JL, Smith NM. Multicarbazole scaffolds for selective G-quadruplex binding. Chemical Communications (Cambridge, England). PMID 30101241 DOI: 10.1039/C8Cc03945C  0.51
2018 Zuffo M, Guédin A, Leriche ED, Doria F, Pirota V, Gabelica V, Mergny JL, Freccero M. More is not always better: finding the right trade-off between affinity and selectivity of a G-quadruplex ligand. Nucleic Acids Research. PMID 29986058 DOI: 10.1093/Nar/Gky607  0.49
2018 Dalloul Z, Chenuet P, Dalloul I, Boyer F, Aldigier JC, Laffleur B, El Makhour Y, Ryffel B, Quesniaux VF, Togbé D, Mergny JL, Cook-Moreau J, Cogné M. G-quadruplex DNA targeting alters class switch recombination in B cells and attenuates allergic inflammation. The Journal of Allergy and Clinical Immunology. PMID 29935221 DOI: 10.1016/J.Jaci.2018.06.011  0.324
2018 Busto N, Calvo P, Santolaya J, Leal JM, Guédin A, Barone G, Torroba T, Mergny JL, García B. FISHING G- QUADRUPLEXES IN SOLUTION WITH A PERYLENE DIIMIDE DERIVATIVE LABELED WITH BIOTINS. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 29797628 DOI: 10.1002/Chem.201802365  0.528
2018 Guédin A, Lin LY, Armane S, Lacroix L, Mergny JL, Thore S, Yatsunyk LA. Quadruplexes in 'Dicty': crystal structure of a four-quartet G-quadruplex formed by G-rich motif found in the Dictyostelium discoideum genome. Nucleic Acids Research. PMID 29718337 DOI: 10.1093/Nar/Gky290  0.821
2018 Carvalho J, Quintela T, Gueddouda NM, Bourdoncle A, Mergny JL, Salgado GF, Queiroz JA, Cruz C. Phenanthroline polyazamacrocycles as G-quadruplex DNA binders. Organic & Biomolecular Chemistry. PMID 29611599 DOI: 10.1039/C8Ob00247A  0.541
2018 Belmonte-Reche E, Martínez-García M, Guédin A, Zuffo M, Arévalo-Ruiz M, Doria F, Campos-Salinas J, Maynadier M, Lopez-Rubio JJ, Freccero M, Mergny JL, Perez-Victoria JM, Morales JC. G-quadruplex identification in the genome of protozoan parasites points to naphthalene diimide ligands as new antiparasitic agents. Journal of Medicinal Chemistry. PMID 29323491 DOI: 10.1021/Acs.Jmedchem.7B01672  0.514
2018 Chen J, Zhang Y, Cheng M, Guo Y, Šponer J, Monchaud D, Mergny J, Ju H, Zhou J. How Proximal Nucleobases Regulate the Catalytic Activity of G-Quadruplex/Hemin DNAzymes Acs Catalysis. 8: 11352-11361. DOI: 10.1021/Acscatal.8B03811  0.459
2017 Das RN, Chevret E, Desplat V, Rubio S, Mergny JL, Guillon J. Design, Synthesis and Biological Evaluation of New Substituted Diquinolinyl-Pyridine Ligands as Anticancer Agents by Targeting G-Quadruplex. Molecules (Basel, Switzerland). 23. PMID 29301210 DOI: 10.3390/Molecules23010081  0.72
2017 Guillon J, Cohen A, Das RN, Boudot C, Gueddouda NM, Moreau S, Ronga L, Savrimoutou S, Basmaciyan L, Tisnerat C, Mestanier S, Rubio S, Amaziane S, Dassonville-Klimpt A, Azas N, ... ... Mergny JL, et al. Design, synthesis, and antiprotozoal evaluation of new 2,9-bis[(substituted-aminomethyl)phenyl]-1,10-phenanthroline derivatives. Chemical Biology & Drug Design. PMID 29266861 DOI: 10.1111/Cbdd.13164  0.613
2017 Dzatko S, Krafcikova M, Hänsel-Hertsch R, Fessl T, Fiala R, Loja T, Krafcik D, Mergny JL, Foldynova-Trantirkova S, Trantirek L. Evaluation of stability of DNA i-motifs in the nuclei of living mammalian cells. Angewandte Chemie (International Ed. in English). PMID 29266664 DOI: 10.1002/Anie.201712284  0.493
2017 Marquevielle J, Kumar MVV, Mergny JL, Salgado GF. 1H, 13C, and 15N chemical shift assignments of a G-quadruplex forming sequence within the KRAS proto-oncogene promoter region. Biomolecular Nmr Assignments. PMID 29189986 DOI: 10.1007/S12104-017-9793-0  0.508
2017 Carvalho J, Pereira E, Marquevielle J, Campello MPC, Mergny JL, Paulo A, Salgado GF, Queiroz JA, Cruz C. Fluorescent light-up acridine orange derivatives bind and stabilize KRAS-22RT G-quadruplex. Biochimie. PMID 29129745 DOI: 10.1016/J.Biochi.2017.11.004  0.499
2017 Cheng M, Zhou J, Jia G, Ai X, Mergny JL, Li C. Relations between the loop transposition of DNA G-quadruplex and the catalytic function of DNAzyme. Biochimica Et Biophysica Acta. PMID 28533132 DOI: 10.1016/J.Bbagen.2017.05.016  0.527
2017 Zhou J, Amrane S, Rosu F, Salgado GF, Bian Y, Tateishi-Karimata H, Largy E, Korkut DN, Bourdoncle A, Miyoshi D, Zhang J, Ju H, Wang W, Sugimoto N, Gabelica V, ... Mergny JL, et al. Unexpected Position-dependent Effects of Ribose G-quartets in G-quadruplexes. Journal of the American Chemical Society. PMID 28523907 DOI: 10.1021/Jacs.7B00648  0.512
2017 Kerkour A, Marquevielle J, Ivashchenko S, Yatsunyk LA, Mergny JL, Salgado GF. High-resolution 3D NMR structure of the KRAS proto-oncogene promoter reveals key features of a G-quadruplex involved in transcriptional regulation. The Journal of Biological Chemistry. PMID 28330874 DOI: 10.1074/Jbc.M117.781906  0.521
2017 Carvalho J, Nottelet P, Mergny JL, Queiroz JA, Salgado GF, Cruz C. Study of the interaction between indole-based compounds and biologically relevant G-quadruplexes. Biochimie. PMID 28232078 DOI: 10.1016/J.Biochi.2017.02.005  0.511
2017 Guillon J, Cohen A, Gueddouda NM, Das RN, Moreau S, Ronga L, Savrimoutou S, Basmaciyan L, Monnier A, Monget M, Rubio S, Garnerin T, Azas N, Mergny JL, Mullié C, et al. Design, synthesis and antimalarial activity of novel bis{N-[(pyrrolo[1,2-a]quinoxalin-4-yl)benzyl]-3-aminopropyl}amine derivatives. Journal of Enzyme Inhibition and Medicinal Chemistry. 32: 547-563. PMID 28114821 DOI: 10.1080/14756366.2016.1268608  0.599
2017 Gueddouda NM, Mendoza O, Gomez D, Bourdoncle A, Mergny JL. G-quadruplexes unfolding by RHAU helicase. Biochimica Et Biophysica Acta. PMID 28065761 DOI: 10.1016/J.Bbagen.2017.01.006  0.556
2017 Marquevielle J, VKMV, Mergny J, Salgado GF. 1H, 13C, and 15N resonance assignments of a 22mer G-quadruplex forming within KRAS oncogene promoter region at physiological temperature Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.13018/Bmr27173  0.356
2017 Salgado G, Marquevielle J, Kerkour A, Mergny J. NMR chemical shift assignments of a 22mer G-quadruplex formed within the KRAS proto-oncogene promoter region Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.13018/Bmr27053  0.411
2016 Wang M, Mao Z, Kang TS, Wong CY, Mergny JL, Leung CH, Ma DL. Conjugating a groove-binding motif to an Ir(iii) complex for the enhancement of G-quadruplex probe behavior. Chemical Science. 7: 2516-2523. PMID 28660021 DOI: 10.1039/C6Sc00001K  0.462
2016 Kerkour A, Mergny JL, Salgado GF. NMR based model of human telomeric repeat G-quadruplex in complex with 2,4,6-triarylpyridine family ligand. Biochimica Et Biophysica Acta. PMID 28007578 DOI: 10.1016/J.Bbagen.2016.12.016  0.532
2016 Arevalo M, Doria F, Belmonte-Reche E, De Rache A, Campos-Salinas J, Lucas R, Falomir E, Carda M, Pérez-Victoria JM, Mergny JL, Freccero M, Morales JC. Synthesis, binding properties and differences on cell uptake of G-quadruplex ligands based on carbohydrate naphthalene diimide conjugates. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 27925323 DOI: 10.1002/Chem.201604886  0.48
2016 Gueddouda NM, Hurtado MR, Moreau S, Ronga L, Das RN, Savrimoutou S, Rubio S, Marchand A, Mendoza O, Marchivie M, Elmi L, Chansavang A, Desplat V, Gabelica V, Bourdoncle A, ... Mergny JL, et al. Design, synthesis, and evaluation of 2,9-bis[(substituted-aminomethyl)phenyl]-1,10-phenanthroline derivatives as G-quadruplex ligands. Chemmedchem. PMID 27917615 DOI: 10.1002/Cmdc.201600511  0.686
2016 Medeiros-Silva J, Guédin A, Salgado GF, Mergny JL, Queiroz JA, Cabrita EJ, Cruz C. Phenanthroline-bis-oxazole ligands for binding and stabilization of G-quadruplexes. Biochimica Et Biophysica Acta. PMID 27865994 DOI: 10.1016/j.bbagen.2016.11.024  0.384
2016 Lin S, Lu L, Kang TS, Liu C, Mergny JL, Leung CH, Ma DL. The interaction of an iridium(III) complex with G-quadruplex DNA and its application in luminescent switch-on detection of Siglec-5. Analytical Chemistry. PMID 27678199 DOI: 10.1021/Acs.Analchem.6B03128  0.513
2016 De Rache A, Gueddouda NM, Bourdoncle A, Hommes P, Reissig HU, Mergny JL. A Flexible Terpyridine Derivative Interacts Specifically with G-Quadruplexes. Chemistry (Weinheim An Der Bergstrasse, Germany). 22: 12651-4. PMID 27410717 DOI: 10.1002/Chem.201603021  0.485
2016 Lecarme L, Prado E, De Rache A, Nicolau-Travers ML, Gellon G, Dejeu J, Lavergne T, Jamet H, Gomez D, Mergny JL, Defrancq E, Jarjayes O, Thomas F. Efficient Inhibition of Telomerase by Nickel-Salophen Complexes. Chemmedchem. PMID 27166712 DOI: 10.1002/Cmdc.201600171  0.337
2016 Mendoza O, Bourdoncle A, Boulé JB, Brosh RM, Mergny JL. G-quadruplexes and helicases. Nucleic Acids Research. 44: 1989-2006. PMID 26883636 DOI: 10.1093/Nar/Gkw079  0.552
2016 Largy E, Mergny JL, Gabelica V. Role of Alkali Metal Ions in G-Quadruplex Nucleic Acid Structure and Stability. Metal Ions in Life Sciences. 16: 203-58. PMID 26860303 DOI: 10.1007/978-3-319-21756-7_7  0.534
2016 Largy E, Marchand A, Amrane S, Gabelica V, Mergny JL. Quadruplex turncoats: cation-dependent folding and stability of quadruplex-DNA double switches. Journal of the American Chemical Society. PMID 26837276 DOI: 10.1021/Jacs.5B13130  0.553
2016 Bedrat A, Lacroix L, Mergny JL. Re-evaluation of G-quadruplex propensity with G4Hunter. Nucleic Acids Research. 44: 1746-59. PMID 26792894 DOI: 10.1093/Nar/Gkw006  0.812
2016 Saintomé C, Amrane S, Mergny JL, Alberti P. The exception that confirms the rule: a higher-order telomeric G-quadruplex structure more stable in sodium than in potassium. Nucleic Acids Research. 44: 2926-35. PMID 26762980 DOI: 10.1093/Nar/Gkw003  0.54
2016 Sabharwal NC, Mendoza O, Nicoludis JM, Ruan T, Mergny JL, Yatsunyk LA. Investigation of the interactions between Pt(II) and Pd(II) derivatives of 5,10,15,20-tetrakis (N-methyl-4-pyridyl) porphyrin and G-quadruplex DNA. Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry. 21: 227-39. PMID 26748794 DOI: 10.1007/S00775-015-1325-8  0.495
2016 Mendoza O, Mergny JL, Aimé JP, Elezgaray J. G-Quadruplexes Light up Localized DNA Circuits. Nano Letters. 16: 624-8. PMID 26717099 DOI: 10.1021/Acs.Nanolett.5B04354  0.416
2016 Noer SL, Preus S, Gudnason D, Aznauryan M, Mergny JL, Birkedal V. Folding dynamics and conformational heterogeneity of human telomeric G-quadruplex structures in Na+ solutions by single molecule FRET microscopy. Nucleic Acids Research. 44: 464-71. PMID 26615192 DOI: 10.1093/Nar/Gkv1320  0.372
2016 Carvalho J, Ferreira J, Pereira P, Coutinho E, Guédin A, Nottelet P, Salgado GF, Mergny JL, Queiroz JA, Sousa F, Cabrita EJ, Cruz C. Stabilization of novel immunoglobulin switch regions G-quadruplexes by naphthalene and quinoline-based ligands Tetrahedron. 72: 1229-1237. DOI: 10.1016/J.Tet.2016.01.022  0.538
2015 Lin S, Gao W, Tian Z, Yang C, Lu L, Mergny JL, Leung CH, Ma DL. Luminescence switch-on detection of protein tyrosine kinase-7 using a G-quadruplex-selective probe. Chemical Science. 6: 4284-4290. PMID 29218197 DOI: 10.1039/C5Sc01320H  0.494
2015 Salgado GF, Cazenave C, Kerkour A, Mergny JL. G-quadruplex DNA and ligand interaction in living cells using NMR spectroscopy. Chemical Science. 6: 3314-3320. PMID 28706695 DOI: 10.1039/c4sc03853c  0.433
2015 Zhou J, Tateishi-Karimata H, Mergny JL, Cheng M, Feng Z, Miyoshi D, Sugimoto N, Li C. Reevaluation of the stability of G-quadruplex structures under crowding conditions. Biochimie. PMID 26708323 DOI: 10.1016/J.Biochi.2015.12.012  0.499
2015 Mendoza O, Elezgaray J, Mergny JL. Spectroscopic data for the G-quadruplex DNA to duplex DNA reaction. Data in Brief. 5: 822-8. PMID 26693518 DOI: 10.1016/J.Dib.2015.10.039  0.471
2015 Merle P, Gueugneau M, Teulade-Fichou MP, Müller-Barthélémy M, Amiard S, Chautard E, Guetta C, Dedieu V, Communal Y, Mergny JL, Gallego M, White C, Verrelle P, Tchirkov A. Highly efficient radiosensitization of human glioblastoma and lung cancer cells by a G-quadruplex DNA binding compound. Scientific Reports. 5: 16255. PMID 26542881 DOI: 10.1038/Srep16255  0.472
2015 Mendoza O, Elezgaray J, Mergny JL. Kinetics of quadruplex to duplex conversion. Biochimie. 118: 225-33. PMID 26427557 DOI: 10.1016/J.Biochi.2015.09.031  0.518
2015 Lin S, He B, Yang C, Leung CH, Mergny JL, Ma DL. Luminescence switch-on assay of interferon-gamma using a G-quadruplex-selective iridium(iii) complex. Chemical Communications (Cambridge, England). PMID 26399215 DOI: 10.1039/c5cc06655g  0.366
2015 Castillo-González D, Mergny JL, De Rache A, Pérez-Machado G, Cabrera-Pérez MA, Nicolotti O, Introcaso A, Mangiatordi GF, Guédin A, Bourdoncle A, Garrigues T, Pallardó F, Cordeiro MN, Paz-Y-Miño C, Tejera E, et al. Harmonization of QSAR Best Practices and Molecular Docking Provides an Efficient Virtual Screening Tool for Discovering New G-Quadruplex Ligands. Journal of Chemical Information and Modeling. 55: 2094-110. PMID 26355653 DOI: 10.1021/Acs.Jcim.5B00415  0.481
2015 De Rache A, Mergny JL. Assessment of selectivity of G-quadruplex ligands via an optimised FRET melting assay. Biochimie. 115: 194-202. PMID 26079222 DOI: 10.1016/J.Biochi.2015.06.002  0.545
2015 Rajendran A, Endo M, Hidaka K, Teulade-Fichou MP, Mergny JL, Sugiyama H. Small molecule binding to a G-hairpin and a G-triplex: a new insight into anticancer drug design targeting G-rich regions. Chemical Communications (Cambridge, England). 51: 9181-4. PMID 25951794 DOI: 10.1039/C5Cc01678A  0.464
2015 Sabater L, Nicolau-Travers ML, De Rache A, Prado E, Dejeu J, Bombarde O, Lacroix J, Calsou P, Defrancq E, Mergny JL, Gomez D, Pratviel G. The nickel(II) complex of guanidinium phenyl porphyrin, a specific G-quadruplex ligand, targets telomeres and leads to POT1 mislocalization in culture cells. Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry. 20: 729-38. PMID 25846142 DOI: 10.1007/S00775-015-1260-8  0.454
2015 Wang M, He B, Lu L, Leung CH, Mergny JL, Ma DL. Label-free luminescent detection of LMP1 gene deletion using an intermolecular G-quadruplex-based switch-on probe. Biosensors & Bioelectronics. 70: 338-44. PMID 25840020 DOI: 10.1016/J.Bios.2015.03.047  0.411
2015 Mendoza O, Porrini M, Salgado GF, Gabelica V, Mergny JL. Orienting tetramolecular G-quadruplex formation: the quest for the elusive RNA antiparallel quadruplex. Chemistry (Weinheim An Der Bergstrasse, Germany). 21: 6732-9. PMID 25820943 DOI: 10.1002/Chem.201500358  0.428
2015 Mendoza O, Gueddouda NM, Boulé JB, Bourdoncle A, Mergny JL. A fluorescence-based helicase assay: application to the screening of G-quadruplex ligands. Nucleic Acids Research. 43: e71. PMID 25765657 DOI: 10.1093/nar/gkv193  0.455
2015 Sabater L, Fang PJ, Chang CF, De Rache A, Prado E, Dejeu J, Garofalo A, Lin JH, Mergny JL, Defrancq E, Pratviel G. Cobalt(III)porphyrin to target G-quadruplex DNA. Dalton Transactions (Cambridge, England : 2003). 44: 3701-7. PMID 25573281 DOI: 10.1039/C4Dt03631J  0.521
2015 Davis KJ, Richardson C, Beck JL, Knowles BM, Guédin A, Mergny JL, Willis AC, Ralph SF. Synthesis and characterisation of nickel Schiff base complexes containing the meso-1,2-diphenylethylenediamine moiety: selective interactions with a tetramolecular DNA quadruplex. Dalton Transactions (Cambridge, England : 2003). 44: 3136-50. PMID 25572696 DOI: 10.1039/C4Dt02926G  0.414
2015 Salgado GF, Cazenave C, Kerkour A, Mergny JL. G-quadruplex DNA and ligand interaction in living cells using NMR spectroscopy Chemical Science. 6: 3314-3320. DOI: 10.1039/c4sc03853c  0.432
2015 Mendoza O, Porrini M, Salgado GF, Gabelica V, Mergny J. Frontispiece: Orienting Tetramolecular G‐Quadruplex Formation: The Quest for the Elusive RNA Antiparallel Quadruplex Chemistry: a European Journal. 21. DOI: 10.1002/Chem.201581862  0.319
2014 Lecarme L, Prado E, De Rache A, Nicolau-Travers ML, Bonnet R, van Der Heyden A, Philouze C, Gomez D, Mergny JL, Jamet H, Defrancq E, Jarjayes O, Thomas F. Interaction of polycationic Ni(II)-salophen complexes with G-quadruplex DNA. Inorganic Chemistry. 53: 12519-31. PMID 25383703 DOI: 10.1021/Ic502063R  0.524
2014 Perriaud L, Marcel V, Sagne C, Favaudon V, Guédin A, De Rache A, Guetta C, Hamon F, Teulade-Fichou MP, Hainaut P, Mergny JL, Hall J. Impact of G-quadruplex structures and intronic polymorphisms rs17878362 and rs1642785 on basal and ionizing radiation-induced expression of alternative p53 transcripts. Carcinogenesis. 35: 2706-15. PMID 25269805 DOI: 10.1093/Carcin/Bgu206  0.346
2014 Bharti SK, Sommers JA, Zhou J, Kaplan DL, Spelbrink JN, Mergny JL, Brosh RM. DNA sequences proximal to human mitochondrial DNA deletion breakpoints prevalent in human disease form G-quadruplexes, a class of DNA structures inefficiently unwound by the mitochondrial replicative Twinkle helicase. The Journal of Biological Chemistry. 289: 29975-93. PMID 25193669 DOI: 10.1074/Jbc.M114.567073  0.412
2014 Largy E, Mergny JL. Shape matters: size-exclusion HPLC for the study of nucleic acid structural polymorphism. Nucleic Acids Research. 42: e149. PMID 25143531 DOI: 10.1093/Nar/Gku751  0.399
2014 Yatsunyk LA, Mendoza O, Mergny JL. "Nano-oddities": unusual nucleic acid assemblies for DNA-based nanostructures and nanodevices. Accounts of Chemical Research. 47: 1836-44. PMID 24871086 DOI: 10.1021/Ar500063X  0.471
2014 Ma DL, Lin S, Leung KH, Zhong HJ, Liu LJ, Chan DS, Bourdoncle A, Mergny JL, Wang HM, Leung CH. An oligonucleotide-based label-free luminescent switch-on probe for RNA detection utilizing a G-quadruplex-selective iridium(III) complex. Nanoscale. 6: 8489-94. PMID 24816304 DOI: 10.1039/C4Nr00541D  0.401
2014 Amrane S, Kerkour A, Bedrat A, Vialet B, Andreola ML, Mergny JL. Topology of a DNA G-quadruplex structure formed in the HIV-1 promoter: a potential target for anti-HIV drug development. Journal of the American Chemical Society. 136: 5249-52. PMID 24649937 DOI: 10.1021/Ja501500C  0.444
2014 Renaud de la Faverie A, Guédin A, Bedrat A, Yatsunyk LA, Mergny JL. Thioflavin T as a fluorescence light-up probe for G4 formation. Nucleic Acids Research. 42: e65. PMID 24510097 DOI: 10.1093/Nar/Gku111  0.456
2014 Zhou J, Rosu F, Amrane S, Korkut DN, Gabelica V, Mergny JL. Assembly of chemically modified G-rich sequences into tetramolecular DNA G-quadruplexes and higher order structures Methods. 67: 159-168. PMID 24434505 DOI: 10.1016/J.Ymeth.2014.01.004  0.449
2014 Amrane S, Bedrat A, Faverie ARDL, Zhou J, Mendoza O, Rache AD, Guedin A, Largy E, Amor S, Salgado G, Bourdoncle A, Yatsunyk LA, Mergny J. Quadruplexes are everywhere Collection of Czechoslovak Chemical Communications. 14: 62-65. DOI: 10.1135/Css201414062  0.494
2014 Rajendran A, Endo M, Hidaka K, Tran PLT, Teulade-Fichou M, Mergny J, Sugiyama H. G-quadruplex-binding ligand-induced DNA synapsis inside a DNA origami frame Rsc Advances. 4: 6346-6355. DOI: 10.1039/C3Ra45676E  0.514
2014 Kragh SL, Preus S, Gudnason D, Mergny J, Birkedal V. Structural Dynamics and Polymorphism of Telomeric G-Quadruplex DNA Structures Biophysical Journal. 106: 65a. DOI: 10.1016/J.Bpj.2013.11.438  0.553
2013 Rajendran A, Endo M, Hidaka K, Tran PL, Mergny JL, Gorelick RJ, Sugiyama H. HIV-1 nucleocapsid proteins as molecular chaperones for tetramolecular antiparallel G-quadruplex formation. Journal of the American Chemical Society. 135: 18575-85. PMID 24224650 DOI: 10.1021/Ja409085J  0.424
2013 Mergny JL. Meeting report: Fourth international meeting on G-quadruplex Nucleic Acids (Singapore, July 1-4, 2013). Biochimie. 95: 2320-5. PMID 24120569 DOI: 10.1016/J.Biochi.2013.08.033  0.454
2013 Zhou J, Abramov M, Liu F, Amrane S, Bourdoncle A, Herdewijn P, Mergny JL. Effects of six-membered carbohydrate rings on structure, stability, and kinetics of G-quadruplexes. Chemistry (Weinheim An Der Bergstrasse, Germany). 19: 14719-25. PMID 24027098 DOI: 10.1002/Chem.201301743  0.507
2013 Rajendran A, Endo M, Hidaka K, Tran PL, Mergny JL, Sugiyama H. Controlling the stoichiometry and strand polarity of a tetramolecular G-quadruplex structure by using a DNA origami frame. Nucleic Acids Research. 41: 8738-47. PMID 23863846 DOI: 10.1093/Nar/Gkt592  0.559
2013 Zhou J, Amrane S, Korkut DN, Bourdoncle A, He HZ, Ma DL, Mergny JL. Combination of i-motif and G-quadruplex structures within the same strand: formation and application. Angewandte Chemie (International Ed. in English). 52: 7742-6. PMID 23775868 DOI: 10.1002/Anie.201301278  0.514
2013 Yatsunyk LA, Piétrement O, Albrecht D, Tran PL, Ren?iuk D, Sugiyama H, Arbona JM, Aimé JP, Mergny JL. Guided assembly of tetramolecular G-quadruplexes. Acs Nano. 7: 5701-10. PMID 23763613 DOI: 10.1021/Nn402321G  0.543
2013 Leung KH, He HZ, Ma VP, Zhong HJ, Chan DS, Zhou J, Mergny JL, Leung CH, Ma DL. Detection of base excision repair enzyme activity using a luminescent G-quadruplex selective switch-on probe. Chemical Communications (Cambridge, England). 49: 5630-2. PMID 23559154 DOI: 10.1039/C3Cc41129J  0.382
2013 He HZ, Leung KH, Yang H, Chan DS, Leung CH, Zhou J, Bourdoncle A, Mergny JL, Ma DL. Label-free detection of sub-nanomolar lead(II) ions in aqueous solution using a metal-based luminescent switch-on probe. Biosensors & Bioelectronics. 41: 871-4. PMID 23040875 DOI: 10.1016/J.Bios.2012.08.060  0.354
2013 Castillo-González D, Pérez-Machado G, Guédin A, Mergny JL, Cabrera-Pérez MA. FDA-approved drugs selected using virtual screening bind specifically to G-quadruplex DNA. Current Pharmaceutical Design. 19: 2164-73. PMID 23016840 DOI: 10.2174/1381612811319120004  0.544
2013 Tran PL, De Cian A, Gros J, Moriyama R, Mergny JL. Tetramolecular quadruplex stability and assembly. Topics in Current Chemistry. 330: 243-73. PMID 22752578 DOI: 10.1007/128_2012_334  0.525
2013 Zhou J, Murayama K, Amrane S, Rosu F, Kashida H, Bourdoncle A, Asanuma H, Mergny JL. A "sugar-deficient" G-quadruplex: Incorporation of aTNA in G4 structures Chemical Science. 4: 3693-3698. DOI: 10.1039/C3Sc50474C  0.528
2012 Smith NM, Amrane S, Rosu F, Gabelica V, Mergny JL. Mercury-thymine interaction with a chair type G-quadruplex architecture Chemical Communications. 48: 11464-11466. PMID 23090661 DOI: 10.1039/C2Cc36481F  0.509
2012 Zhou J, Bourdoncle A, Rosu F, Gabelica V, Mergny JL. Tri-G-quadruplex: Controlled assembly of a G-quadruplex structure from three G-rich strands Angewandte Chemie - International Edition. 51: 11002-11005. PMID 23038222 DOI: 10.1002/Anie.201205390  0.519
2012 Petenzi M, Verga D, Largy E, Hamon F, Doria F, Teulade-Fichou MP, Guédin A, Mergny JL, Mella M, Freccero M. Cationic pentaheteroaryls as selective G-quadruplex ligands by solvent-free microwave-assisted synthesis. Chemistry (Weinheim An Der Bergstrasse, Germany). 18: 14487-96. PMID 22996572 DOI: 10.1002/Chem.201202097  0.528
2012 Ma DL, He HZ, Ma VP, Chan DS, Leung KH, Zhong HJ, Lu L, Mergny JL, Leung CH. Label-free sensing of pH and silver nanoparticles using an "OR" logic gate. Analytica Chimica Acta. 733: 78-83. PMID 22704379 DOI: 10.1016/J.Aca.2012.04.041  0.314
2012 Renčiuk D, Zhou J, Beaurepaire L, Guédin A, Bourdoncle A, Mergny JL. A FRET-based screening assay for nucleic acid ligands. Methods (San Diego, Calif.). 57: 122-8. PMID 22465278 DOI: 10.1016/J.Ymeth.2012.03.020  0.389
2012 Amrane S, Adrian M, Heddi B, Serero A, Nicolas A, Mergny JL, Phan AT. Formation of pearl-necklace monomorphic G-quadruplexes in the human CEB25 minisatellite. Journal of the American Chemical Society. 134: 5807-16. PMID 22376028 DOI: 10.1021/Ja208993R  0.513
2012 Nicoludis JM, Barrett SP, Mergny JL, Yatsunyk LA. Interaction of human telomeric DNA with N-methyl mesoporphyrin IX. Nucleic Acids Research. 40: 5432-47. PMID 22362740 DOI: 10.1093/Nar/Gks152  0.498
2012 Mergny JL. Alternative DNA structures: G4 DNA in cells: itae missa est? Nature Chemical Biology. 8: 225-6. PMID 22337092 DOI: 10.1038/Nchembio.793  0.524
2012 Amrane S, Adrian M, Heddi B, Serero A, Nicolas A, Mergny J, Phan AT. human CEB25 minisatellite G-quadruplex Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.2210/Pdb2Lpw/Pdb  0.419
2011 Largy E, Hamon F, Rosu F, Gabelica V, De Pauw E, Guédin A, Mergny JL, Teulade-Fichou MP. Tridentate N-donor palladium(II) complexes as efficient coordinating quadruplex DNA binders. Chemistry (Weinheim An Der Bergstrasse, Germany). 17: 13274-83. PMID 22006796 DOI: 10.1002/Chem.201102300  0.371
2011 Merle P, Evrard B, Petitjean A, Lehn JM, Teulade-Fichou MP, Chautard E, De Cian A, Guittat L, Tran PL, Mergny JL, Verrelle P, Tchirkov A. Telomere targeting with a new G4 ligand enhances radiation-induced killing of human glioblastoma cells. Molecular Cancer Therapeutics. 10: 1784-95. PMID 21987532 DOI: 10.1158/1535-7163.Mct-10-0664  0.378
2011 Hamon F, Largy E, Guédin-Beaurepaire A, Rouchon-Dagois M, Sidibe A, Monchaud D, Mergny JL, Riou JF, Nguyen CH, Teulade-Fichou MP. An acyclic oligoheteroaryle that discriminates strongly between diverse G-quadruplex topologies. Angewandte Chemie (International Ed. in English). 50: 8745-9. PMID 21812083 DOI: 10.1002/Anie.201103422  0.513
2011 Smith NM, Labrunie G, Corry B, Tran PL, Norret M, Djavaheri-Mergny M, Raston CL, Mergny JL. Unraveling the relationship between structure and stabilization of triarylpyridines as G-quadruplex binding ligands. Organic & Biomolecular Chemistry. 9: 6154-62. PMID 21750831 DOI: 10.1039/C1Ob05560G  0.551
2011 Renaud de la Faverie A, Hamon F, Di Primo C, Largy E, Dausse E, Delaurière L, Landras-Guetta C, Toulmé JJ, Teulade-Fichou MP, Mergny JL. Nucleic acids targeted to drugs: SELEX against a quadruplex ligand. Biochimie. 93: 1357-67. PMID 21664224 DOI: 10.1016/J.Biochi.2011.05.022  0.53
2011 Tran PL, Largy E, Hamon F, Teulade-Fichou MP, Mergny JL. Fluorescence intercalator displacement assay for screening G4 ligands towards a variety of G-quadruplex structures. Biochimie. 93: 1288-96. PMID 21641961 DOI: 10.1016/J.Biochi.2011.05.011  0.51
2011 Tran PL, Moriyama R, Maruyama A, Rayner B, Mergny JL. A mirror-image tetramolecular DNA quadruplex. Chemical Communications (Cambridge, England). 47: 5437-9. PMID 21483923 DOI: 10.7490/F1000Research.1987.1  0.424
2011 Stefan L, Guédin A, Amrane S, Smith N, Denat F, Mergny JL, Monchaud D. DOTASQ as a prototype of nature-inspired G-quadruplex ligand. Chemical Communications (Cambridge, England). 47: 4992-4. PMID 21431124 DOI: 10.1039/C0Cc04960C  0.506
2011 Bertrand H, Granzhan A, Monchaud D, Saettel N, Guillot R, Clifford S, Guédin A, Mergny JL, Teulade-Fichou MP. Recognition of G-quadruplex DNA by triangular star-shaped compounds: With or without side chains? Chemistry - a European Journal. 17: 4529-4539. PMID 21416510 DOI: 10.1002/Chem.201002810  0.508
2011 Tran PL, Mergny JL, Alberti P. Stability of telomeric G-quadruplexes. Nucleic Acids Research. 39: 3282-94. PMID 21177648 DOI: 10.1093/Nar/Gkq1292  0.524
2011 Marcel V, Tran PL, Sagne C, Martel-Planche G, Vaslin L, Teulade-Fichou MP, Hall J, Mergny JL, Hainaut P, Van Dyck E. G-quadruplex structures in TP53 intron 3: role in alternative splicing and in production of p53 mRNA isoforms. Carcinogenesis. 32: 271-8. PMID 21112961 DOI: 10.1093/Carcin/Bgq253  0.459
2011 Lacroix L, Séosse A, Mergny JL. Fluorescence-based duplex-quadruplex competition test to screen for telomerase RNA quadruplex ligands. Nucleic Acids Research. 39: e21. PMID 21106496 DOI: 10.1093/Nar/Gkq1199  0.801
2011 Tran PL, Virgilio A, Esposito V, Citarella G, Mergny JL, Galeone A. Effects of 8-methylguanine on structure, stability and kinetics of formation of tetramolecular quadruplexes. Biochimie. 93: 399-408. PMID 21034790 DOI: 10.1016/J.Biochi.2010.10.011  0.5
2011 Mergny J, Yatsunyk L, Guedin A, Gros J, Faverie ARDL, Smith N, Renciuk D, Tran PLT, Bourdoncle A. DNA quadruplexes for bio- and nanotechnologies Collection of Czechoslovak Chemical Communications. 12: 218-221. DOI: 10.1135/Css201112218  0.429
2010 Eritja R, Mergny JL, Montesarchio D, Spindler L, Webba da Silva M. G-quadruplex nucleic acids. Journal of Nucleic Acids. 2010. PMID 20814544 DOI: 10.4061/2010/147650  0.432
2010 Monchaud D, Granzhan A, Saettel N, Guédin A, Mergny JL, Teulade-Fichou MP. "One ring to bind them all"-part I: the efficiency of the macrocyclic scaffold for g-quadruplex DNA recognition. Journal of Nucleic Acids. 2010. PMID 20725629 DOI: 10.4061/2010/525862  0.506
2010 Granzhan A, Monchaud D, Saettel N, Guédin A, Mergny JL, Teulade-Fichou MP. "One Ring to Bind Them All"-Part II: Identification of Promising G-Quadruplex Ligands by Screening of Cyclophane-Type Macrocycles. Journal of Nucleic Acids. 2010. PMID 20725622 DOI: 10.4061/2010/460561  0.394
2010 Guédin A, Gros J, Alberti P, Mergny JL. How long is too long? Effects of loop size on G-quadruplex stability Nucleic Acids Research. 38: 7858-7868. PMID 20660477 DOI: 10.1093/Nar/Gkq639  0.418
2010 Gomez D, Guédin A, Mergny JL, Salles B, Riou JF, Teulade-Fichou MP, Calsou P. A G-quadruplex structure within the 5'-UTR of TRF2 mRNA represses translation in human cells. Nucleic Acids Research. 38: 7187-98. PMID 20571083 DOI: 10.1093/Nar/Gkq563  0.544
2010 Guédin A, Lacroix L, Mergny JL. Thermal melting studies of ligand DNA interactions. Methods in Molecular Biology (Clifton, N.J.). 613: 25-35. PMID 19997875 DOI: 10.1007/978-1-60327-418-0_2  0.768
2010 Monchaud D, Granzhan A, Saettel N, Guédin A, Mergny JL, Teulade-Fichou MP. "One ring to bind them all" - Part I: The efficiency of the macrocyclic scaffold for G-quadruplex DNA recognition Journal of Nucleic Acids. 2010. DOI: 10.4061/2010/525862  0.368
2010 Granzhan A, Monchaud D, Saettel N, Guédin A, Mergny JL, Teulade-Fichou MP. "One ring to bind them all" - Fication of promising G-quadruplex ligands by screening of cyclophane-type macrocycles Journal of Nucleic Acids. 2010. DOI: 10.4061/2010/460561  0.384
2009 Lim KW, Alberti P, Guédin A, Lacroix L, Riou JF, Royle NJ, Mergny JL, Phan AT. Sequence variant (CTAGGG)n in the human telomere favors a G-quadruplex structure containing a G.C.G.C tetrad. Nucleic Acids Research. 37: 6239-48. PMID 19692585 DOI: 10.1093/Nar/Gkp630  0.816
2009 Mendez-Bermudez A, Hills M, Pickett HA, Phan AT, Mergny JL, Riou JF, Royle NJ. Human telomeres that contain (CTAGGG)n repeats show replication dependent instability in somatic cells and the male germline. Nucleic Acids Research. 37: 6225-38. PMID 19656953 DOI: 10.1093/Nar/Gkp629  0.346
2009 Bertrand H, Bombard S, Monchaud D, Talbot E, Guédin A, Mergny JL, Grünert R, Bednarski PJ, Teulade-Fichou MP. Exclusive platination of loop adenines in the human telomeric G-quadruplex. Organic & Biomolecular Chemistry. 7: 2864-71. PMID 19582295 DOI: 10.1039/B904599F  0.451
2009 Guédin A, Alberti P, Mergny JL. Stability of intramolecular quadruplexes: sequence effects in the central loop. Nucleic Acids Research. 37: 5559-67. PMID 19581426 DOI: 10.1093/Nar/Gkp563  0.374
2009 Mergny JL, Lacroix L. UV Melting of G-Quadruplexes. Current Protocols in Nucleic Acid Chemistry. Unit 17.1. PMID 19488970 DOI: 10.1002/0471142700.Nc1701S37  0.776
2009 Stegle O, Payet L, Mergny JL, MacKay DJ, Leon JH. Predicting and understanding the stability of G-quadruplexes. Bioinformatics (Oxford, England). 25: i374-82. PMID 19478012 DOI: 10.1093/Bioinformatics/Btp210  0.494
2009 El Bakali J, Klupsch F, Guédin A, Brassart B, Fontaine G, Farce A, Roussel P, Houssin R, Bernier JL, Chavatte P, Mergny JL, Riou JF, Hénichart JP. 2,6-Diphenylthiazolo[3,2-b][1,2,4]triazoles as telomeric G-quadruplex stabilizers. Bioorganic & Medicinal Chemistry Letters. 19: 3434-8. PMID 19473838 DOI: 10.1016/J.Bmcl.2009.05.025  0.509
2009 Ribeyre C, Lopes J, Boulé JB, Piazza A, Guédin A, Zakian VA, Mergny JL, Nicolas A. The yeast Pif1 helicase prevents genomic instability caused by G-quadruplex-forming CEB1 sequences in vivo. Plos Genetics. 5: e1000475. PMID 19424434 DOI: 10.1371/Journal.Pgen.1000475  0.453
2009 Yang P, De Cian A, Teulade-Fichou MP, Mergny JL, Monchaud D. Engineering bisquinolinium/thiazole orange conjugates for fluorescent sensing of G-quadruplex DNA. Angewandte Chemie (International Ed. in English). 48: 2188-91. PMID 19199323 DOI: 10.1002/Anie.200805613  0.436
2008 De Cian A, Grellier P, Mouray E, Depoix D, Bertrand H, Monchaud D, Teulade-Fichou MP, Mergny JL, Alberti P. Plasmodium telomeric sequences: structure, stability and quadruplex targeting by small compounds. Chembiochem : a European Journal of Chemical Biology. 9: 2730-9. PMID 18924216 DOI: 10.1002/Cbic.200800330  0.528
2008 Lyonnais S, Piétrement O, Chepelianski A, Guéron S, Lacroix L, Le Cam E, Mergny JL. Functionalization of DNA G-Wires for patterning and nanofabrication. Nucleic Acids Symposium Series (2004). 689-90. PMID 18776567 DOI: 10.1093/nass/nrn348  0.801
2008 De Cian A, Gros J, Guédin A, Haddi M, Lyonnais S, Guittat L, Riou JF, Trentesaux C, Saccà B, Lacroix L, Alberti P, Mergny JL. DNA and RNA quadruplex ligands. Nucleic Acids Symposium Series (2004). 7-8. PMID 18776226 DOI: 10.1093/nass/nrn004  0.81
2008 Gros J, Guédin A, Mergny JL, Lacroix L. G-quadruplex formation interferes with P1 helix formation in the RNA component of telomerase hTERC Chembiochem. 9: 2075-2079. PMID 18683270 DOI: 10.1002/Cbic.200800300  0.777
2008 Gros J, Aviñó A, Lopez de la Osa J, González C, Lacroix L, Pérez A, Orozco M, Eritja R, Mergny JL. 8-Amino guanine accelerates tetramolecular G-quadruplex formation. Chemical Communications (Cambridge, England). 2926-8. PMID 18566727 DOI: 10.1039/B801221K  0.795
2008 Monchaud D, Yang P, Lacroix L, Teulade-Fichou MP, Mergny JL. A metal-mediated conformational switch controls G-quadruplex binding affinity. Angewandte Chemie (International Ed. in English). 47: 4858-61. PMID 18496803 DOI: 10.1002/Anie.200800468  0.763
2008 Amrane S, De Cian A, Rosu F, Kaiser M, De Pauw E, Teulade-Fichou MP, Mergny JL. Identification of trinucleotide repeat ligands with a FRET melting assay. Chembiochem : a European Journal of Chemical Biology. 9: 1229-34. PMID 18386278 DOI: 10.1002/Cbic.200800062  0.433
2008 Rosu F, Gabelica V, De Pauw E, Mailliet P, Mergny JL. Cooperative 2:1 binding of a bisphenothiazine to duplex DNA. Chembiochem : a European Journal of Chemical Biology. 9: 849-52. PMID 18307188 DOI: 10.1002/Cbic.200700572  0.463
2008 Guédin A, De Cian A, Gros J, Lacroix L, Mergny JL. Sequence effects in single-base loops for quadruplexes. Biochimie. 90: 686-96. PMID 18294461 DOI: 10.1016/J.Biochi.2008.01.009  0.792
2008 Cheng MK, Modi C, Cookson JC, Hutchinson I, Heald RA, McCarroll AJ, Missailidis S, Tanious F, Wilson WD, Mergny JL, Laughton CA, Stevens MF. Antitumor polycyclic acridines. 20. Search for DNA quadruplex binding selectivity in a series of 8,13-dimethylquino[4,3,2-kl]acridinium salts: telomere-targeted agents. Journal of Medicinal Chemistry. 51: 963-75. PMID 18247546 DOI: 10.1021/Jm070587T  0.455
2008 Mills M, Mergny JL, Klump HH. From quadruplex to helix and back: meta-stable states can move through a cycle of conformational changes. Archives of Biochemistry and Biophysics. 474: 8-14. PMID 18191034 DOI: 10.1016/j.abb.2007.12.015  0.316
2008 Bertrand H, Monchaud D, De Cian A, Guillot R, Mergny JL, Teulade-Fichou MP. The importance of metal geometry in the recognition of G-quadruplex-DNA by metal-terpyridine complexes. Organic & Biomolecular Chemistry. 5: 2555-9. PMID 18019527 DOI: 10.1039/B708635K  0.456
2008 De Cian A, Lacroix L, Douarre C, Temime-Smaali N, Trentesaux C, Riou JF, Mergny JL. Targeting telomeres and telomerase. Biochimie. 90: 131-55. PMID 17822826 DOI: 10.1016/J.Biochi.2007.07.011  0.762
2008 Mergny J. Quadruplexes. What else Collection of Czechoslovak Chemical Communications. 10: 80-86. DOI: 10.1135/Css200810080  0.494
2008 Guittat L, Mergny J. Telomerase Inhibition: Strategies and Protocols. Edited by Lucy G. Andrews and Trygve O. Tollefsbol. Chemmedchem. 3: 1135-1137. DOI: 10.1002/Cmdc.200800107  0.347
2007 De Cian A, Cristofari G, Reichenbach P, De Lemos E, Monchaud D, Teulade-Fichou MP, Shin-Ya K, Lacroix L, Lingner J, Mergny JL. Reevaluation of telomerase inhibition by quadruplex ligands and their mechanisms of action. Proceedings of the National Academy of Sciences of the United States of America. 104: 17347-52. PMID 17954919 DOI: 10.1073/Pnas.0707365104  0.776
2007 Mergny JL, Lacroix L, Riou JF. Telomerase: a dimeric ménage à trois. Chembiochem : a European Journal of Chemical Biology. 8: 1483-5. PMID 17625802 DOI: 10.1002/Cbic.200700272  0.736
2007 Brassart B, Gomez D, De Cian A, Paterski R, Montagnac A, Qui KH, Temime-Smaali N, Trentesaux C, Mergny JL, Gueritte F, Riou JF. A new steroid derivative stabilizes g-quadruplexes and induces telomere uncapping in human tumor cells. Molecular Pharmacology. 72: 631-40. PMID 17586599 DOI: 10.1124/Mol.107.036574  0.536
2007 De Cian A, Guittat L, Kaiser M, Saccà B, Amrane S, Bourdoncle A, Alberti P, Teulade-Fichou MP, Lacroix L, Mergny JL. Fluorescence-based melting assays for studying quadruplex ligands. Methods (San Diego, Calif.). 42: 183-95. PMID 17472900 DOI: 10.1016/J.Ymeth.2006.10.004  0.811
2007 Gros J, Rosu F, Amrane S, De Cian A, Gabelica V, Lacroix L, Mergny JL. Guanines are a quartet's best friend: Impact of base substitutions on the kinetics and stability of tetramolecular quadruplexes Nucleic Acids Research. 35: 3064-3075. PMID 17452368 DOI: 10.1093/Nar/Gkm111  0.802
2007 De Cian A, Mergny JL. Quadruplex ligands may act as molecular chaperones for tetramolecular quadruplex formation. Nucleic Acids Research. 35: 2483-93. PMID 17395639 DOI: 10.1093/Nar/Gkm098  0.486
2007 Hounsou C, Guittat L, Monchaud D, Jourdan M, Saettel N, Mergny JL, Teulade-Fichou MP. G-quadruplex recognition by quinacridines: A SAR, NMR, and biological study Chemmedchem. 2: 655-666. PMID 17385760 DOI: 10.1002/Cmdc.200600286  0.495
2007 De Cian A, Delemos E, Mergny JL, Teulade-Fichou MP, Monchaud D. Highly efficient G-quadruplex recognition by bisquinolinium compounds. Journal of the American Chemical Society. 129: 1856-7. PMID 17260991 DOI: 10.1021/Ja067352B  0.434
2007 De Cian A, Guittat L, Shin-ya K, Riou JF, Mergny JL. Affinity and selectivity of G4 ligands measured by FRET. Nucleic Acids Symposium Series (2004). 235-6. PMID 17150720 DOI: 10.1093/NASS/49.1.235  0.478
2006 Alberti P, Bourdoncle A, Saccà B, Lacroix L, Mergny JL. DNA nanomachines and nanostructures involving quadruplexes. Organic & Biomolecular Chemistry. 4: 3383-91. PMID 17036128 DOI: 10.1039/B605739J  0.812
2006 Salas TR, Petruseva I, Lavrik O, Bourdoncle A, Mergny JL, Favre A, Saintomé C. Human replication protein A unfolds telomeric G-quadruplexes. Nucleic Acids Research. 34: 4857-65. PMID 16973897 DOI: 10.1093/Nar/Gkl564  0.552
2006 Mergny JL, De Cian A, Amrane S, Webba da Silva M. Kinetics of double-chain reversals bridging contiguous quartets in tetramolecular quadruplexes. Nucleic Acids Research. 34: 2386-97. PMID 16682446 DOI: 10.1093/Nar/Gkl098  0.505
2006 Kaiser M, De Cian A, Sainlos M, Renner C, Mergny JL, Teulade-Fichou MP. Neomycin-capped aromatic platforms: quadruplex DNA recognition and telomerase inhibition. Organic & Biomolecular Chemistry. 4: 1049-57. PMID 16525549 DOI: 10.1039/B516378A  0.559
2005 Gros J, Webba da Silva M, De Cian A, Amrane S, Rosu F, Bourdoncle A, Saccà B, Alberti P, Lacroix L, Mergny JL. Kinetics and thermodynamics of G-quadruplexes. Nucleic Acids Symposium Series (2004). 61-2. PMID 17150633 DOI: 10.1093/nass/49.1.61  0.809
2005 Mergny JL, Li J, Lacroix L, Amrane S, Chaires JB. Thermal difference spectra: a specific signature for nucleic acid structures. Nucleic Acids Research. 33: e138. PMID 16157860 DOI: 10.1093/Nar/Gni134  0.76
2005 Granotier C, Pennarun G, Riou L, Hoffschir F, Gauthier LR, De Cian A, Gomez D, Mandine E, Riou JF, Mergny JL, Mailliet P, Dutrillaux B, Boussin FD. Preferential binding of a G-quadruplex ligand to human chromosome ends. Nucleic Acids Research. 33: 4182-90. PMID 16052031 DOI: 10.1093/Nar/Gki722  0.483
2005 Amrane S, Saccà B, Mills M, Chauhan M, Klump HH, Mergny JL. Length-dependent energetics of (CTG)n and (CAG)n trinucleotide repeats. Nucleic Acids Research. 33: 4065-77. PMID 16040598 DOI: 10.1093/Nar/Gki716  0.393
2005 Guittat L, De Cian A, Rosu F, Gabelica V, De Pauw E, Delfourne E, Mergny JL. Ascididemin and meridine stabilise G-quadruplexes and inhibit telomerase in vitro Biochimica Et Biophysica Acta - General Subjects. 1724: 375-384. PMID 15950388 DOI: 10.1016/J.Bbagen.2005.04.023  0.511
2005 Riou JF, Gomez D, Mergny JL, Guittat L, Paterski R, Chenais B, Morjani H, Trentesaux C. [Regulation of telomeres length: making the telomeres accessible?]. Bulletin Du Cancer. 92: 13-22. PMID 15811846  0.306
2005 Pennarun G, Granotier C, Gauthier LR, Gomez D, Hoffschir F, Mandine E, Riou JF, Mergny JL, Mailliet P, Boussin FD. Apoptosis related to telomere instability and cell cycle alterations in human glioma cells treated by new highly selective G-quadruplex ligands. Oncogene. 24: 2917-28. PMID 15735722 DOI: 10.1038/Sj.Onc.1208468  0.462
2005 Saccà B, Lacroix L, Mergny JL. The effect of chemical modifications on the thermal stability of different G-quadruplex-forming oligonucleotides. Nucleic Acids Research. 33: 1182-92. PMID 15731338 DOI: 10.1093/Nar/Gki257  0.802
2005 Mergny JL, De Cian A, Ghelab A, Saccà B, Lacroix L. Kinetics of tetramolecular quadruplexes. Nucleic Acids Research. 33: 81-94. PMID 15642696 DOI: 10.1093/Nar/Gki148  0.791
2005 Mergny JL, Li J, Lacroix L, Amrane S, Chaires JB. Thermal difference spectra: A specific signature for nucleic acid structures Nucleic Acids Research. 33: 1-6. DOI: 10.1093/nar/gni134  0.72
2004 Guittat L, Alberti P, Gomez D, De Cian A, Pennarun G, Lemarteleur T, Belmokhtar C, Paterski R, Morjani H, Trentesaux C, Mandine E, Boussin F, Mailliet P, Lacroix L, Riou JF, ... Mergny JL, et al. Targeting human telomerase for cancer therapeutics. Cytotechnology. 45: 75-90. PMID 19003245 DOI: 10.1007/S10616-004-5127-Z  0.762
2004 Horn V, Lacroix L, Gautier T, Takasugi M, Mergny JL, Lacoste J. Triple helix formation with Drosophila satellite repeats. Unexpected stabilization by copper ions. Biochemistry. 43: 11196-205. PMID 15366929 DOI: 10.1021/Bi049287T  0.778
2004 Gomez D, Paterski R, Lemarteleur T, Shin-ya K, Mergny J, Riou J. Interaction of telomestatin with the telomeric single-strand overhang Journal of Biological Chemistry. 279: 41487-41494. PMID 15277522 DOI: 10.1074/Jbc.M406123200  0.553
2004 Gomez D, Lemarteleur T, Lacroix L, Mailliet P, Mergny JL, Riou JF. Telomerase downregulation induced by the G-quadruplex ligand 12459 in A549 cells is mediated by hTERT RNA alternative splicing. Nucleic Acids Research. 32: 371-9. PMID 14729921 DOI: 10.1093/Nar/Gkh181  0.789
2003 Mergny JL, Lacroix L. Analysis of thermal melting curves. Oligonucleotides. 13: 515-37. PMID 15025917 DOI: 10.1089/154545703322860825  0.773
2003 Gomez D, Aouali N, Londoño-Vallejo A, Lacroix L, Mégnin-Chanet F, Lemarteleur T, Douarre C, Shin-ya K, Mailliet P, Trentesaux C, Morjani H, Mergny JL, Riou JF. Resistance to the short term antiproliferative activity of the G-quadruplex ligand 12459 is associated with telomerase overexpression and telomere capping alteration. The Journal of Biological Chemistry. 278: 50554-62. PMID 14525974 DOI: 10.1074/Jbc.M308440200  0.785
2003 Lyonnais S, Gorelick RJ, Mergny JL, Le Cam E, Mirambeau G. G-quartets direct assembly of HIV-1 nucleocapsid protein along single-stranded DNA Nucleic Acids Research. 31: 5754-5763. PMID 14500839 DOI: 10.1093/Nar/Gkg716  0.459
2003 Rosu F, De Pauw E, Guittat L, Alberti P, Lacroix L, Mailliet P, Riou JF, Mergny JL. Selective interaction of ethidium derivatives with quadruplexes: an equilibrium dialysis and electrospray ionization mass spectrometry analysis. Biochemistry. 42: 10361-71. PMID 12950163 DOI: 10.1021/Bi034531M  0.797
2003 Guittat L, Alberti P, Rosu F, Van Miert S, Thetiot E, Pieters L, Gabelica V, De Pauw E, Ottaviani A, Riou JF, Mergny JL. Interactions of cryptolepine and neocryptolepine with unsual DNA structures Biochimie. 85: 535-547. PMID 12763313 DOI: 10.1016/S0300-9084(03)00035-X  0.489
2003 Teulade-Fichou MP, Carrasco C, Guittat L, Bailly C, Alberti P, Mergny JL, David A, Lehn JM, Wilson WD. Selective recognition of G-qQuadruplex telomeric DNA by a bis(quinacridine) macrocycle. Journal of the American Chemical Society. 125: 4732-40. PMID 12696891 DOI: 10.1021/Ja021299J  0.547
2003 Alberti P, Mergny JL. DNA duplex-quadruplex exchange as the basis for a nanomolecular machine. Proceedings of the National Academy of Sciences of the United States of America. 100: 1569-73. PMID 12574521 DOI: 10.1073/Pnas.0335459100  0.365
2003 Alberti P, Lacroix L, Guittat L, Hélène C, Mergny JL. Nucleic acids as targets for antitelomerase agents. Mini Reviews in Medicinal Chemistry. 3: 23-36. PMID 12570852 DOI: 10.2174/1389557033405485  0.791
2002 Mills M, Lacroix L, Arimondo PB, Leroy JL, François JC, Klump H, Mergny JL. Unusual DNA conformations: Implications for telomeres Current Medicinal Chemistry - Anti-Cancer Agents. 2: 627-644. PMID 12678729 DOI: 10.2174/1568011023353877  0.821
2002 Alberti P, Arimondo PB, Mergny JL, Garestier T, Hélène C, Sun JS. A directional nucleation-zipping mechanism for triple helix formation. Nucleic Acids Research. 30: 5407-15. PMID 12490709 DOI: 10.1093/Nar/Gkf675  0.621
2002 Phan AT, Mergny JL. Human telomeric DNA: G-quadruplex, i-motif and Watson-Crick double helix. Nucleic Acids Research. 30: 4618-25. PMID 12409451 DOI: 10.1093/Nar/Gkf597  0.559
2002 Gomez D, Mergny JL, Riou JF. Detection of telomerase inhibitors based on g-quadruplex ligands by a modified telomeric repeat amplification protocol assay. Cancer Research. 62: 3365-8. PMID 12067975  0.334
2002 Alberti P, Schmitt P, Nguyen CH, Rivalle C, Hoarau M, Grierson DS, Mergny JL. Benzoindoloquinolines interact with DNA tetraplexes and inhibit telomerase. Bioorganic & Medicinal Chemistry Letters. 12: 1071-4. PMID 11909720 DOI: 10.1016/S0960-894X(02)00080-X  0.547
2002 Riou JF, Guittat L, Mailliet P, Laoui A, Renou E, Petitgenet O, Mégnin-Chanet F, Hélène C, Mergny JL. Cell senescence and telomere shortening induced by a new series of specific G-quadruplex DNA ligands. Proceedings of the National Academy of Sciences of the United States of America. 99: 2672-7. PMID 11854467 DOI: 10.1073/pnas.052698099  0.605
2002 Mergny JL, Riou JF, Mailliet P, Teulade-Fichou MP, Gilson E. Natural and pharmacological regulation of telomerase. Nucleic Acids Research. 30: 839-65. PMID 11842096 DOI: 10.1093/Nar/30.4.839  0.419
2002 Mergny JL, Maurizot JC. Fluorescence resonance energy transfer as a probe for G-quartet formation by a telomeric repeat. Chembiochem : a European Journal of Chemical Biology. 2: 124-32. PMID 11828436 DOI: 10.1002/1439-7633(20010202)2:2<124::Aid-Cbic124>3.0.Co;2-L  0.412
2002 Mills M, Arimondo PB, Lacroix L, Garestier T, Klump H, Mergny JL. Chemical modification of the third strand: differential effects on purine and pyrimidine triple helix formation. Biochemistry. 41: 357-66. PMID 11772035 DOI: 10.1021/Bi011122M  0.794
2001 Alberti P, Ren J, Teulade-Fichou MP, Guittat L, Riou JF, Chaires J, Hélène C, Vigneron JP, Lehn JM, Mergny JL. Interaction of an acridine dimer with DNA quadruplex structures. Journal of Biomolecular Structure & Dynamics. 19: 505-13. PMID 11790148 DOI: 10.1080/07391102.2001.10506758  0.688
2001 Mergny JL, Lacroix L, Teulade-Fichou MP, Hounsou C, Guittat L, Hoarau M, Arimondo PB, Vigneron JP, Lehn JM, Riou JF, Garestier T, Hélène C. Telomerase inhibitors based on quadruplex ligands selected by a fluorescence assay. Proceedings of the National Academy of Sciences of the United States of America. 98: 3062-7. PMID 11248032 DOI: 10.1073/Pnas.051620698  0.839
2001 Koeppel F, Riou JF, Laoui A, Mailliet P, Arimondo PB, Labit D, Petitgenet O, Hélène C, Mergny JL. Ethidium derivatives bind to G-quartets, inhibit telomerase and act as fluorescent probes for quadruplexes. Nucleic Acids Research. 29: 1087-96. PMID 11222758 DOI: 10.1093/Nar/29.5.1087  0.661
2000 Arimondo PB, Riou JF, Mergny JL, Tazi J, Sun JS, Garestier T, Hélène C. Interaction of human DNA topoisomerase I with G-quartet structures. Nucleic Acids Research. 28: 4832-8. PMID 11121473 DOI: 10.1093/Nar/28.24.4832  0.679
2000 Lacroix L, Mergny JL. Chemical modification of pyrimidine TFOs: effect on i-motif and triple helix formation. Archives of Biochemistry and Biophysics. 381: 153-63. PMID 11019831 DOI: 10.1006/Abbi.2000.1934  0.801
2000 Lacroix L, Arimondo PB, Takasugi M, Hélène C, Mergny JL. Pyrimidine morpholino oligonucleotides form a stable triple helix in the absence of magnesium ions. Biochemical and Biophysical Research Communications. 270: 363-9. PMID 10753631 DOI: 10.1006/Bbrc.2000.2438  0.808
2000 Lacroix L, Liénard H, Labourier E, Djavaheri-Mergny M, Lacoste J, Leffers H, Tazi J, Hélène C, Mergny JL. Identification of two human nuclear proteins that recognise the cytosine-rich strand of human telomeres in vitro. Nucleic Acids Research. 28: 1564-75. PMID 10710423 DOI: 10.1093/Nar/28.7.1564  0.78
2000 François JC, Lacoste J, Lacroix L, Mergny JL. Design of antisense and triplex-forming oligonucleotides. Methods in Enzymology. 313: 74-95. PMID 10595350 DOI: 10.1016/S0076-6879(00)13006-X  0.783
1999 Mills M, Arimondo PB, Lacroix L, Garestier T, Hélène C, Klump H, Mergny JL. Energetics of strand-displacement reactions in triple helices: a spectroscopic study. Journal of Molecular Biology. 291: 1035-54. PMID 10518941 DOI: 10.1006/Jmbi.1999.3014  0.811
1999 Lacroix L, Lacoste J, Reddoch JF, Mergny JL, Levy DD, Seidman MM, Matteucci MD, Glazer PM. Triplex formation by oligonucleotides containing 5-(1-propynyl)-2'-deoxyuridine: decreased magnesium dependence and improved intracellular gene targeting. Biochemistry. 38: 1893-901. PMID 10026270 DOI: 10.1021/Bi982290Q  0.803
1999 Mergny JL. Fluorescence energy transfer as a probe for tetraplex formation: the i-motif. Biochemistry. 38: 1573-81. PMID 9931024 DOI: 10.1021/Bi982208R  0.387
1998 Mergny JL, Hélène C. G-quadruplex DNA: a target for drug design. Nature Medicine. 4: 1366-7. PMID 9846570 DOI: 10.1038/3949  0.653
1998 Mergny JL, Lacroix L. Kinetics and thermodynamics of i-DNA formation: phosphodiester versus modified oligodeoxynucleotides. Nucleic Acids Research. 26: 4797-803. PMID 9776737 DOI: 10.1093/Nar/26.21.4797  0.398
1998 Mergny JL, Phan AT, Lacroix L. Following G-quartet formation by UV-spectroscopy. Febs Letters. 435: 74-8. PMID 9755862 DOI: 10.1016/S0014-5793(98)01043-6  0.786
1996 Faucon B, Mergny JL, Héléne C. Effect of third strand composition on the triple helix formation: purine versus pyrimidine oligodeoxynucleotides. Nucleic Acids Research. 24: 3181-8. PMID 8774898 DOI: 10.1093/Nar/24.16.3181  0.666
1996 Lacroix L, Mergny JL, Leroy JL, Hélène C. Inability of RNA to form the i-motif: implications for triplex formation. Biochemistry. 35: 8715-22. PMID 8679634 DOI: 10.1021/Bi960107S  0.827
1995 Duval-Valentin G, de Bizemont T, Takasugi M, Mergny JL, Bisagni E, Hélène C. Triple-helix specific ligands stabilize H-DNA conformation. Journal of Molecular Biology. 247: 847-58. PMID 7723037 DOI: 10.1006/Jmbi.1995.0185  0.637
1995 Escudé C, Nguyen CH, Mergny JL, Sun JS, Bisagni E, Garestier T, Hélène C. Selective stabilization of DNA triple helices by benzopyridoindole derivatives Journal of the American Chemical Society. 117: 10212-10219. DOI: 10.1021/Ja00146A006  0.598
1995 Mergny JL, Lacroix L, Han X, Leroy JL, Hélène C. Intramolecular folding of pyrimidine oligodeoxynucleotides into an i-DNA motif Journal of the American Chemical Society. 117: X-8898. DOI: 10.1021/Ja00140A001  0.808
1994 Leroy JL, Guéron M, Mergny JL, Hélène C. Intramolecular folding of a fragment of the cytosine-rich strand of telomeric DNA into an i-motif. Nucleic Acids Research. 22: 1600-6. PMID 8202359 DOI: 10.1093/Nar/22.9.1600  0.709
1994 Mergny JL, Boutorine AS, Garestier T, Belloc F, Rougée M, Bulychev NV, Koshkin AA, Bourson J, Lebedev AV, Valeur B. Fluorescence energy transfer as a probe for nucleic acid structures and sequences. Nucleic Acids Research. 22: 920-8. PMID 8152922 DOI: 10.1093/Nar/22.6.920  0.345
1994 Mergny JL, Garestier T, Rougée M, Lebedev AV, Chassignol M, Thuong NT, Hélène C. Fluorescence energy transfer between two triple helix-forming oligonucleotides bound to duplex DNA. Biochemistry. 33: 15321-8. PMID 7803395 DOI: 10.1021/Bi00255A013  0.598
1992 Mergny JL, Duval-Valentin G, Nguyen CH, Perrouault L, Faucon B, Rougée M, Montenay-Garestier T, Bisagni E, Hélène C. Triple helix-specific ligands. Science (New York, N.Y.). 256: 1681-4. PMID 1609278  0.594
1991 Mergny JL, Collier D, Rougée M, Montenay-Garestier T, Hélène C. Intercalation of ethidium bromide into a triple-stranded oligonucleotide Nucleic Acids Research. 19: 1521-1526. PMID 2027760 DOI: 10.1093/Nar/19.7.1521  0.604
1991 Mergny JL, Sun JS, Rougée M, Montenay-Garestier T, Barcelo F, Chomilier J, Hélène C. Sequence specificity in triple-helix formation: experimental and theoretical studies of the effect of mismatches on triplex stability. Biochemistry. 30: 9791-8. PMID 1911764 DOI: 10.1021/Bi00104A031  0.432
1991 Collier DA, Mergny JL, Thuong NT, Helene C. Site-specific intercalation at the triplex-duplex junction induces a conformational change which is detectable by hypersensitivity to diethylpyrocarbonate. Nucleic Acids Research. 19: 4219-24. PMID 1870975 DOI: 10.1093/Nar/19.15.4219  0.586
1991 Mergny JL, Slama-Schwok A, Montenay-Garestier T, Rougée M, Hélène C. Fluorescence energy transfer between dimethyldiazaperopyrenium dication and ethidium intercalated in poly d(A-T) Photochemistry and Photobiology. 53: 555-558. PMID 1857748 DOI: 10.1111/J.1751-1097.1991.Tb03670.X  0.522
1991 Sun JS, Mergny JL, Garestier TM, Lavery R, Hélène C. Triple helix structures: Sequence dependence, flexibility and mismatch effects Journal of Biomolecular Structure and Dynamics. 9: 411-424. PMID 1815635 DOI: 10.1080/07391102.1991.10507925  0.611
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