Konstantinos Chiotis - Related publications

Affiliations: 
Karolinska Institute, Stockholm, Sweden 
Area:
Alzheimer's disease. Positron Emission Tomography
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50 most relevant papers in past 60 days:
Year Citation  Score
2020 La Joie R, Visani AV, Baker SL, Brown JA, Bourakova V, Cha J, Chaudhary K, Edwards L, Iaccarino L, Janabi M, Lesman-Segev OH, Miller ZA, Perry DC, O'Neil JP, Pham J, et al. Prospective longitudinal atrophy in Alzheimer's disease correlates with the intensity and topography of baseline tau-PET. Science Translational Medicine. 12. PMID 31894103 DOI: 10.1126/scitranslmed.aau5732   
2020 Polis B, Samson AO. Role of the metabolism of branched-chain amino acids in the development of Alzheimer's disease and other metabolic disorders. Neural Regeneration Research. 15: 1460-1470. PMID 31997805 DOI: 10.4103/1673-5374.274328   
2020 Parbo P, Madsen LS, Ismail R, Zetterberg H, Blennow K, Eskildsen SF, Vorup-Jensen T, Brooks DJ. Low plasma neurofilament light levels associated with raised cortical microglial activation suggest inflammation acts to protect prodromal Alzheimer's disease. Alzheimer's Research & Therapy. 12: 3. PMID 31898549 DOI: 10.1186/s13195-019-0574-0   
2020 Gao H, Liu M, Zhao Z, Yang C, Zhu L, Cai Y, Yang Y, Hu Z. Diagnosis of Mild Cognitive Impairment and Alzheimer's Disease by the Plasma and Serum Amyloid-beta 42 Assay through Highly Sensitive Peptoid Nanosheet Sensor. Acs Applied Materials & Interfaces. PMID 32013375 DOI: 10.1021/acsami.0c00370   
2020 Weigand AJ, Bangen KJ, Thomas KR, Delano-Wood L, Gilbert PE, Brickman AM, Bondi MW, . Is tau in the absence of amyloid on the Alzheimer's continuum?: A study of discordant PET positivity. Brain Communications. 2: fcz046. PMID 32051933 DOI: 10.1093/braincomms/fcz046   
2020 Ji X, Wang H, Zhu M, He Y, Zhang H, Chen X, Gao W, Fu Y, . Brainstem atrophy in the early stage of Alzheimer's disease: a voxel-based morphometry study. Brain Imaging and Behavior. PMID 31898091 DOI: 10.1007/s11682-019-00231-3   
2020 Lu G, Liu W, Huang X, Zhao Y. Complement factor H levels are decreased and correlated with serum C-reactive protein in late-onset Alzheimer's disease. Arquivos De Neuro-Psiquiatria. PMID 32022122 DOI: 10.1590/0004-282X20190151   
2020 Kaplow J, Vandijck M, Gray J, Kanekiyo M, Huyck E, Traynham CJ, Esquivel R, Fagan AM, Luthman J. Concordance of Lumipulse cerebrospinal fluid t-tau/Aβ42 ratio with amyloid PET status. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 16: 144-152. PMID 31914216 DOI: 10.1002/alz.12000   
2020 Cai JH, He Y, Zhong XL, Lei H, Wang F, Luo GH, Zhao H, Liu JC. Magnetic Resonance Texture Analysis in Alzheimer's disease. Academic Radiology. PMID 32057617 DOI: 10.1016/j.acra.2020.01.006   
2020 Jeon Y, Lee JH, Choi B, Won SY, Cho KS. Genetic Dissection of Alzheimer's Disease Using Models. International Journal of Molecular Sciences. 21. PMID 32019113 DOI: 10.3390/ijms21030884   
2020 Singh RK. Recent trends in management of Alzheimer's disease: Current therapeutic options and drug repurposing approaches. Current Neuropharmacology. PMID 31989900 DOI: 10.2174/1570159X18666200128121920   
2020 Meyer PF, Binette AP, Gonneaud J, Breitner JCS, Villeneuve S. Characterization of Alzheimer Disease Biomarker Discrepancies Using Cerebrospinal Fluid Phosphorylated Tau and AV1451 Positron Emission Tomography. Jama Neurology. PMID 31961372 DOI: 10.1001/jamaneurol.2019.4749   
2020 Whitwell JL, Tosakulwong N, Weigand SD, Graff-Radford J, Duffy JR, Clark HM, Machulda MM, Botha H, Utianski RL, Schwarz CG, Senjem ML, Strand EA, Ertekin-Taner N, Jack CR, Lowe VJ, et al. Longitudinal Amyloid-β PET in Atypical Alzheimer's Disease and Frontotemporal Lobar Degeneration. Journal of Alzheimer's Disease : Jad. PMID 32039841 DOI: 10.3233/JAD-190699   
2020 Franzmeier N, Neitzel J, Rubinski A, Smith R, Strandberg O, Ossenkoppele R, Hansson O, Ewers M, . Functional brain architecture is associated with the rate of tau accumulation in Alzheimer's disease. Nature Communications. 11: 347. PMID 31953405 DOI: 10.1038/s41467-019-14159-1   
2020 Jääskeläinen O, Hall A, Tiainen M, van Gils M, Lötjönen J, Kangas AJ, Helisalmi S, Pikkarainen M, Hallikainen M, Koivisto A, Hartikainen P, Hiltunen M, Ala-Korpela M, Soininen P, Soininen H, et al. Metabolic Profiles Help Discriminate Mild Cognitive Impairment from Dementia Stage in Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 32007958 DOI: 10.3233/JAD-191226   
2020 Yan T, Liang J, Gao J, Wang L, Fujioka H, , Zhu X, Wang X. FAM222A encodes a protein which accumulates in plaques in Alzheimer's disease. Nature Communications. 11: 411. PMID 31964863 DOI: 10.1038/s41467-019-13962-0   
2020 Tripathi T, Khan H. Direct Interaction between the β-Amyloid Core and Tau Facilitates Cross-Seeding: A Novel Target for Therapeutic Intervention. Biochemistry. PMID 31944100 DOI: 10.1021/acs.biochem.9b01087   
2020 Wilson EN, Swarovski MS, Linortner P, Shahid M, Zuckerman AJ, Wang Q, Channappa D, Minhas PS, Mhatre SD, Plowey ED, Quinn JF, Zabetian CP, Tian L, Longo FM, Cholerton B, et al. Soluble TREM2 is elevated in Parkinson's disease subgroups with increased CSF tau. Brain : a Journal of Neurology. PMID 32065223 DOI: 10.1093/brain/awaa021   
2020 Ferreira D, Nordberg A, Westman E. Biological subtypes of Alzheimer disease: A systematic review and meta-analysis. Neurology. PMID 32047067 DOI: 10.1212/WNL.0000000000009058   
2020 Zeydan B, Lowe VJ, Reichard RR, Przybelski SA, Lesnick TG, Schwarz CG, Senjem ML, Gunter JL, Parisi JE, Machulda MM, Vemuri P, Mielke MM, Knopman DS, Petersen RC, Jack CR, et al. Imaging Biomarkers of Alzheimer's Disease in Multiple Sclerosis. Annals of Neurology. PMID 31970802 DOI: 10.1002/ana.25684   
2020 Malampati S, Song JX, Chun-Kit Tong B, Nalluri A, Yang CB, Wang Z, Gopalkrishnashetty Sreenivasmurthy S, Zhu Z, Liu J, Su C, Krishnamoorthi S, Iyaswamy A, Cheung KH, Lu JH, Li AM. Targeting Aggrephagy for the Treatment of Alzheimer's Disease. Cells. 9. PMID 32012902 DOI: 10.3390/cells9020311   
2020 Iyaswamy A, Krishnamoorthi SK, Song JX, Yang CB, Kaliyamoorthy V, Zhang H, Sreenivasmurthy SG, Malampati S, Wang ZY, Zhu Z, Tong BC, Cheung KH, Lu JH, Durairajan SSK, Li M. NeuroDefend, a novel Chinese medicine, attenuates amyloid-β and tau pathology in experimental Alzheimer's disease models. Journal of Food and Drug Analysis. 28: 132-146. PMID 31883601 DOI: 10.1016/j.jfda.2019.09.004   
2020 Yu Z, Dong W, Wu S, Shen J, Zhao W, Ding L, Liu J, Zheng F. Identification of ovalbumin-derived peptides as multi-target inhibitors of AChE, BChE and BACE1. Journal of the Science of Food and Agriculture. PMID 31997357 DOI: 10.1002/jsfa.10295   
2020 Jung NY, Kim ES, Kim HS, Jeon S, Lee MJ, Pak K, Lee JH, Lee YM, Lee K, Shin JH, Ko JK, Lee JM, Yoon JA, Hwang C, Choi KU, et al. Comparison of Diagnostic Performances Between Cerebrospinal Fluid Biomarkers and Amyloid PET in a Clinical Setting. Journal of Alzheimer's Disease : Jad. PMID 32039853 DOI: 10.3233/JAD-191109   
2020 Alber J, Goldfarb D, Thompson LI, Arthur E, Hernandez K, Cheng D, DeBuc DC, Cordeiro F, Provetti-Cunha L, den Haan J, Van Stavern GP, Salloway SP, Sinoff S, Snyder PJ. Developing retinal biomarkers for the earliest stages of Alzheimer's disease: What we know, what we don't, and how to move forward. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 16: 229-243. PMID 31914225 DOI: 10.1002/alz.12006   
2020 Schrank S, McDaid J, Briggs CA, Mustaly-Kalimi S, Brinks D, Houcek A, Singer O, Bottero V, Marr RA, Stutzmann GE. Human-Induced Neurons from Presenilin 1 Mutant Patients Model Aspects of Alzheimer's Disease Pathology. International Journal of Molecular Sciences. 21. PMID 32033164 DOI: 10.3390/ijms21031030   
2020 Ono K, Zhao D, Wu Q, Simon J, Wang J, Radu A, Pasinetti GM. Pine Bark Polyphenolic Extract Attenuates Amyloid-β and Tau Misfolding in a Model System of Alzheimer's Disease Neuropathology. Journal of Alzheimer's Disease : Jad. PMID 31958081 DOI: 10.3233/JAD-190543   
2020 Xu C, Apostolova LG, Oblak AL, Gao S. Association of Hypercholesterolemia with Alzheimer's Disease Pathology and Cerebral Amyloid Angiopathy. Journal of Alzheimer's Disease : Jad. PMID 31929164 DOI: 10.3233/JAD-191023   
2020 Cannavo C, Tosh J, Fisher EMC, Wiseman FK. Using mouse models to understand Alzheimer's disease mechanisms in the context of trisomy of chromosome 21. Progress in Brain Research. 251: 181-208. PMID 32057307 DOI: 10.1016/bs.pbr.2019.10.004   
2020 Huang LK, Chao SP, Hu CJ. Clinical trials of new drugs for Alzheimer disease. Journal of Biomedical Science. 27: 18. PMID 31906949 DOI: 10.1186/s12929-019-0609-7   
2020 Wisniewski T, Drummond E. APOE-amyloid interaction: Therapeutic targets. Neurobiology of Disease. 104784. PMID 32027932 DOI: 10.1016/j.nbd.2020.104784   
2020 McAllister BB, Lacoursiere SG, Sutherland RJ, Mohajerani MH. Intracerebral seeding of amyloid-β and tau pathology in mice: factors underlying prion-like spreading and comparisons with α-synuclein. Neuroscience and Biobehavioral Reviews. PMID 31996301 DOI: 10.1016/j.neubiorev.2020.01.026   
2020 Uddin MS, Kabir MT, Tewari D, Mathew B, Aleya L. Emerging signal regulating potential of small molecule biflavonoids to combat neuropathological insults of Alzheimer's disease. The Science of the Total Environment. 700: 134836. PMID 31704512 DOI: 10.1016/j.scitotenv.2019.134836   
2020 Nuñez-Borque E, González-Naranjo P, Bartolomé F, Alquézar C, Reinares-Sebastián A, Pérez C, Ceballos ML, Páez JA, Campillo NE, Martín-Requero Á. Targeting Cannabinoid Receptor Activation and BACE-1 Activity Counteracts TgAPP Mice Memory Impairment and Alzheimer's Disease Lymphoblast Alterations. Molecular Neurobiology. PMID 31898159 DOI: 10.1007/s12035-019-01813-4   
2020 Mouchlis VD, Melagraki G, Zacharia LC, Afantitis A. Computer-Aided Drug Design of β-Secretase, γ-Secretase and Anti-Tau Inhibitors for the Discovery of Novel Alzheimer's Therapeutics. International Journal of Molecular Sciences. 21. PMID 31973122 DOI: 10.3390/ijms21030703   
2020 Joung KI, Shin JY, Kim S, Cho SI. Anticholinergic Use Among the Elderly With Alzheimer Disease in South Korea: A Population-based Study. Alzheimer Disease and Associated Disorders. PMID 31913963 DOI: 10.1097/WAD.0000000000000370   
2020 Prikhodko O, Rynearson KD, Sekhon T, Mante MM, Nguyen PD, Rissman RA, Tanzi RE, Wagner SL. The GSM BPN-15606 as a Potential Candidate for Preventative Therapy in Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 31958080 DOI: 10.3233/JAD-190442   
2020 Gao Z, Feng Y, Ma C, Ma K, Cai Q. Disrupted Time-Dependent and Functional Connectivity Brain Network in Alzheimer's Disease: A Resting-State fMRI Study Based on Visibility Graph. Current Alzheimer Research. PMID 32053076 DOI: 10.2174/1567205017666200213100607   
2020 Kramer V, Brooks AF, Haeger A, Kuljs RO, Rafique W, Koeppe RA, Raffel DM, Frey KA, Amaral H, Scott PJH, Riss PJ. Evaluation of [F]N-methyl-lansoprazole as a tau PET imaging agent in first-in-human studies. Acs Chemical Neuroscience. PMID 31898886 DOI: 10.1021/acschemneuro.9b00639   
2020 Schaffert J, LoBue C, White CL, Wilmoth K, Didehbani N, Lacritz L, Nguyen T, Peters ME, Fields L, Li C, Cullum CM. Risk factors for earlier dementia onset in autopsy-confirmed Alzheimer's disease, mixed Alzheimer's with Lewy bodies, and pure Lewy body disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 32043803 DOI: 10.1002/alz.12049   
2020 Mahajan UV, Varma VR, Griswold ME, Blackshear CT, An Y, Oommen AM, Varma S, Troncoso JC, Pletnikova O, O'Brien R, Hohman TJ, Legido-Quigley C, Thambisetty M. Dysregulation of multiple metabolic networks related to brain transmethylation and polyamine pathways in Alzheimer disease: A targeted metabolomic and transcriptomic study. Plos Medicine. 17: e1003012. PMID 31978055 DOI: 10.1371/journal.pmed.1003012   
2020 Lopez OL, Klunk WE, Mathis CA, Snitz BE, Chang Y, Tracy RP, Kuller LH. Relationship of amyloid-β1-42 in blood and brain amyloid: Ginkgo Evaluation of Memory Study. Brain Communications. 2: fcz038. PMID 31998865 DOI: 10.1093/braincomms/fcz038   
2020 Kim K, Kim MJ, Kim DW, Kim SY, Park S, Park CB. Clinically accurate diagnosis of Alzheimer's disease via multiplexed sensing of core biomarkers in human plasma. Nature Communications. 11: 119. PMID 31913282 DOI: 10.1038/s41467-019-13901-z   
2020 Hashweh NN, Bartochowski Z, Khoury R, Grossberg GT. An evaluation of hydromethylthionine as a treatment option for Alzheimer's disease. Expert Opinion On Pharmacotherapy. 1-9. PMID 32037892 DOI: 10.1080/14656566.2020.1719066   
2020 Xuan K, Zhao T, Qu G, Liu H, Chen X, Sun Y. The efficacy of statins in the treatment of Alzheimer's disease: a meta-analysis of randomized controlled trial. Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology. PMID 31930449 DOI: 10.1007/s10072-020-04243-6   
2020 Westwood S, Baird AL, Anand SN, Nevado-Holgado AJ, Kormilitzin A, Shi L, Hye A, Ashton NJ, Morgan AR, Bos I, Vos SJB, Baker S, Buckley NJ, Ten Kate M, Scheltens P, et al. Validation of Plasma Proteomic Biomarkers Relating to Brain Amyloid Burden in the EMIF-Alzheimer's Disease Multimodal Biomarker Discovery Cohort. Journal of Alzheimer's Disease : Jad. PMID 31985466 DOI: 10.3233/JAD-190434   
2020 Beyer L, Brendel M, Scheiwein F, Sauerbeck J, Hosakawa C, Alberts I, Shi K, Bartenstein P, Ishii K, Seibyl J, Cumming P, Rominger A, . Improved Risk Stratification for Progression from Mild Cognitive Impairment to Alzheimer's Disease with a Multi-Analytical Evaluation of Amyloid-β Positron Emission Tomography. Journal of Alzheimer's Disease : Jad. PMID 31985461 DOI: 10.3233/JAD-190818   
2020 Lin C, Ly M, Karim HT, Wei W, Snitz BE, Klunk WE, Aizenstein HJ. The effect of amyloid deposition on longitudinal resting-state functional connectivity in cognitively normal older adults. Alzheimer's Research & Therapy. 12: 7. PMID 31907079 DOI: 10.1186/s13195-019-0573-1   
2020 Castanho I, Murray TK, Hannon E, Jeffries A, Walker E, Laing E, Baulf H, Harvey J, Bradshaw L, Randall A, Moore K, O'Neill P, Lunnon K, Collier DA, Ahmed Z, et al. Transcriptional Signatures of Tau and Amyloid Neuropathology. Cell Reports. 30: 2040-2054.e5. PMID 32049030 DOI: 10.1016/j.celrep.2020.01.063   
2020 Serrano GE, Shprecher D, Callan M, Cutler B, Glass M, Zhang N, Walker J, Intorcia A, Adler CH, Shill HA, Driver-Dunckley E, Mehta SH, Belden CM, Zamrini E, Sue LI, et al. Cardiac sympathetic denervation and synucleinopathy in Alzheimer's disease with brain Lewy body disease. Brain Communications. 2: fcaa004. PMID 32064463 DOI: 10.1093/braincomms/fcaa004