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Raymond D. Blind, PhD - Publications

Affiliations: 
2015- Medicine, Biochemistry & Pharmacology Vanderbilt University, Nashville, TN 
Area:
crystallography, gene expression, nuclear lipid signaling, phospholipid signaling
Website:
https://wag.app.vanderbilt.edu/PublicPage/Faculty/Details/40162
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20 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Seacrist CD, Kuenze G, Hoffmann RM, Moeller BE, Burke JE, Meiler J, Blind RD. Integrated Structural Modeling of Full-Length LRH-1 Reveals Inter-domain Interactions Contribute to Receptor Structure and Function. Structure (London, England : 1993). PMID 32433991 DOI: 10.1016/J.Str.2020.04.020  0.73
2019 Blind RD. Structural analyses of inositol phosphate second messengers bound to signaling effector proteins. Advances in Biological Regulation. 100667. PMID 31648945 DOI: 10.1016/J.Jbior.2019.100667  0.536
2018 Seacrist CD, Blind RD. Crystallographic and kinetic analyses of human IPMK reveal disordered domains modulate ATP binding and kinase activity. Scientific Reports. 8: 16672. PMID 30420721 DOI: 10.1038/S41598-018-34941-3  0.715
2018 Bryant JM, Blind RD. Signaling through non-membrane nuclear phosphoinositide binding proteins in human health and disease. Journal of Lipid Research. PMID 30201631 DOI: 10.1194/Jlr.R088518  0.692
2017 Hamann BL, Blind RD. Nuclear Phosphoinositide Regulation of Chromatin. Journal of Cellular Physiology. PMID 28256711 DOI: 10.1002/Jcp.25886  0.453
2016 Crowder MK, Seacrist CD, Blind RD. Phospholipid regulation of the nuclear receptor superfamily. Advances in Biological Regulation. PMID 27838257 DOI: 10.1016/J.Jbior.2016.10.006  0.749
2016 Malabanan MM, Blind RD. Inositol polyphosphate multikinase (IPMK) in transcriptional regulation and nuclear inositide metabolism. Biochemical Society Transactions. 44: 279-85. PMID 26862216 DOI: 10.1042/Bst20150225  0.729
2015 Sablin EP, Blind RD, Uthayaruban R, Chiu HJ, Deacon AM, Das D, Ingraham HA, Fletterick RJ. Structure of Liver Receptor Homolog-1 (NR5A2) with PIP3 hormone bound in the ligand binding pocket. Journal of Structural Biology. PMID 26416531 DOI: 10.1016/J.Jsb.2015.09.012  0.786
2014 Blind RD, Sablin EP, Kuchenbecker KM, Chiu HJ, Deacon AM, Das D, Fletterick RJ, Ingraham HA. The signaling phospholipid PIP3 creates a new interaction surface on the nuclear receptor SF-1. Proceedings of the National Academy of Sciences of the United States of America. 111: 15054-9. PMID 25288771 DOI: 10.1073/Pnas.1416740111  0.786
2014 Blind RD. Disentangling biological signaling networks by dynamic coupling of signaling lipids to modifying enzymes. Advances in Biological Regulation. 54: 25-38. PMID 24176936 DOI: 10.1016/J.Jbior.2013.09.015  0.42
2012 Blind RD, Suzawa M, Ingraham HA. Direct modification and activation of a nuclear receptor-PIP₂ complex by the inositol lipid kinase IPMK. Science Signaling. 5: ra44. PMID 22715467 DOI: 10.1126/Scisignal.2003111  0.709
2012 Blind RD, Pineda-Torra I, Xu Y, Xu HE, Garabedian MJ. Ligand structural motifs can decouple glucocorticoid receptor transcriptional activation from target promoter occupancy. Biochemical and Biophysical Research Communications. 420: 839-44. PMID 22465009 DOI: 10.1016/J.Bbrc.2012.03.084  0.646
2012 Ingraham HA, Blind RD, VanHook AM. Science Signaling Podcast: 19 June 2012 Science Signaling. 5. DOI: 10.1126/Scisignal.2003287  0.733
2011 Whitby RJ, Stec J, Blind RD, Dixon S, Leesnitzer LM, Orband-Miller LA, Williams SP, Willson TM, Xu R, Zuercher WJ, Cai F, Ingraham HA. Small molecule agonists of the orphan nuclear receptors steroidogenic factor-1 (SF-1, NR5A1) and liver receptor homologue-1 (LRH-1, NR5A2). Journal of Medicinal Chemistry. 54: 2266-81. PMID 21391689 DOI: 10.1021/Jm1014296  0.677
2010 Mullaney BC, Blind RD, Lemieux GA, Perez CL, Elle IC, Faergeman NJ, Van Gilst MR, Ingraham HA, Ashrafi K. Regulation of C. elegans fat uptake and storage by acyl-CoA synthase-3 is dependent on NR5A family nuclear hormone receptor nhr-25. Cell Metabolism. 12: 398-410. PMID 20889131 DOI: 10.1016/J.Cmet.2010.08.013  0.679
2009 Lin BC, Suzawa M, Blind RD, Tobias SC, Bulun SE, Scanlan TS, Ingraham HA. Stimulating the GPR30 estrogen receptor with a novel tamoxifen analogue activates SF-1 and promotes endometrial cell proliferation Cancer Research. 69: 5415-5423. PMID 19549922 DOI: 10.1158/0008-5472.Can-08-1622  0.755
2009 Sablin EP, Blind RD, Krylova IN, Ingraham JG, Cai F, Williams JD, Fletterick RJ, Ingraham HA. Structure of SF-1 bound by different phospholipids: evidence for regulatory ligands. Molecular Endocrinology (Baltimore, Md.). 23: 25-34. PMID 18988706 DOI: 10.1210/Me.2007-0508  0.735
2008 Chen W, Dang T, Blind RD, Wang Z, Cavasotto CN, Hittelman AB, Rogatsky I, Logan SK, Garabedian MJ. Glucocorticoid receptor phosphorylation differentially affects target gene expression. Molecular Endocrinology (Baltimore, Md.). 22: 1754-66. PMID 18483179 DOI: 10.1210/Me.2007-0219  0.789
2008 Blind RD, Garabedian MJ. Differential recruitment of glucocorticoid receptor phospho-isoforms to glucocorticoid-induced genes. The Journal of Steroid Biochemistry and Molecular Biology. 109: 150-7. PMID 18304804 DOI: 10.1016/J.Jsbmb.2008.01.002  0.65
2005 Ismaili N, Blind R, Garabedian MJ. Stabilization of the unliganded glucocorticoid receptor by TSG101. The Journal of Biological Chemistry. 280: 11120-6. PMID 15657031 DOI: 10.1074/Jbc.M500059200  0.706
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