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Year Citation  Score
2022 Banks ML, Hutsell BA, Negus SS. Contextual extinction of drug-associated discriminative stimuli fails to attenuate drug-vs-food choice in rhesus monkeys. Journal of the Experimental Analysis of Behavior. PMID 34990015 DOI: 10.1002/jeab.734  0.306
2021 Moerke MJ, Negus SS, Banks ML. Lack of effect of the nociceptin opioid peptide agonist Ro 64-6198 on pain-depressed behavior and heroin choice in rats. Drug and Alcohol Dependence. 231: 109255. PMID 34998256 DOI: 10.1016/j.drugalcdep.2021.109255  0.339
2021 Baird TR, Davies RA, Glennon RA, Peace MR, Negus SS. A Strategy to Prioritize Emerging Drugs of Abuse for Analysis: Abuse Liability Testing Using Intracranial Self-Stimulation (ICSS) in Rats and Validation with α-Pyrrolidinohexanophenone (α-PHP). Emerging Trends in Drugs, Addictions, and Health. 1. PMID 34296204 DOI: 10.1016/j.etdah.2021.100004  0.335
2021 Cornelissen JC, Blough BE, Bohn LM, Negus SS, Banks ML. Some effects of putative G-protein biased mu-opioid receptor agonists in male rhesus monkeys. Behavioural Pharmacology. PMID 33883450 DOI: 10.1097/FBP.0000000000000634  0.34
2021 Moerke MJ, Negus SS. Temporal parameters of enhanced opioid reward after initial opioid exposure in rats. Psychopharmacology. PMID 33410983 DOI: 10.1007/s00213-020-05725-3  0.307
2020 Bossert JM, Kiyatkin EA, Korah H, Hoots JK, Afzal A, Perekopskiy D, Thomas S, Fredriksson I, Blough BE, Negus SS, Epstein DH, Shaham Y. In a Rat Model of Opioid Maintenance, the G Protein-Biased Mu Opioid Receptor Agonist TRV130 Decreases Relapse to Oxycodone Seeking and Taking and Prevents Oxycodone-Induced Brain Hypoxia. Biological Psychiatry. PMID 32305216 DOI: 10.1016/J.Biopsych.2020.02.014  0.311
2020 Townsend EA, Negus SS, Poklis JL, Banks ML. Lorcaserin maintenance fails to attenuate heroin vs. food choice in rhesus monkeys. Drug and Alcohol Dependence. 107848. PMID 31982193 DOI: 10.1016/j.drugalcdep.2020.107848  0.326
2020 Townsend EA, Negus SS, Banks ML. Medications Development for Treatment of Opioid Use Disorder. Cold Spring Harbor Perspectives in Medicine. PMID 31932466 DOI: 10.1101/cshperspect.a039263  0.306
2019 Lile JA, Johnson AR, Banks ML, Hatton KW, Hays LR, Nicholson KL, Poklis JL, Rayapati AO, Rush CR, Stoops WW, Negus SS. Pharmacological validation of a translational model of cocaine use disorder: Effects of d-amphetamine maintenance on choice between intravenous cocaine and a nondrug alternative in humans and rhesus monkeys. Experimental and Clinical Psychopharmacology. PMID 31259593 DOI: 10.1037/Pha0000302  0.335
2019 Moerke MJ, Negus SS. Role of Agonist Efficacy in Exposure-Induced Enhancement of Mu Opioid Reward in Rats. Neuropharmacology. PMID 30880123 DOI: 10.1016/j.neuropharm.2019.03.020  0.337
2019 Townsend EA, Negus SS, Caine SB, Thomsen M, Banks ML. Sex differences in opioid reinforcement under a fentanyl vs. foodchoice procedure in rats. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 30818323 DOI: 10.1038/S41386-019-0356-1  0.691
2019 Sakloth F, Leggett E, Moerke MJ, Townsend EA, Banks ML, Negus SS. Effects of acute and repeated treatment with serotonin 5-HT2A receptor agonist hallucinogens on intracranial self-stimulation in rats. Experimental and Clinical Psychopharmacology. PMID 30628811 DOI: 10.1037/Pha0000253  0.332
2018 Schwienteck KL, Negus SS, Banks ML. Sex differences in the effectiveness of buprenorphine to decrease rates of responding in rhesus monkeys. Behavioural Pharmacology. PMID 30212383 DOI: 10.1097/FBP.0000000000000437  0.325
2018 Moerke MJ, Ananthan S, Banks ML, Eltit JM, Freitas KC, Johnson AR, Saini SK, Steele TWE, Negus SS. Interactions Between Cocaine and the Putative Allosteric Dopamine Transporter Ligand SRI-31142. The Journal of Pharmacology and Experimental Therapeutics. PMID 30150482 DOI: 10.1124/jpet.118.250902  0.314
2018 Sakloth F, Negus SS. Naltrexone maintenance fails to alter amphetamine effects on intracranial self-stimulation in rats. Experimental and Clinical Psychopharmacology. PMID 29528663 DOI: 10.1037/Pha0000183  0.386
2018 Cornelissen JC, Obeng S, Rice KC, Zhang Y, Negus SS, Banks M. Application of receptor theory to the design and use of fixed-proportion mu-opioid agonist and antagonist mixtures in rhesus monkeys. The Journal of Pharmacology and Experimental Therapeutics. PMID 29330156 DOI: 10.1124/Jpet.117.246439  0.368
2017 Moerke MJ, Banks ML, Cheng K, Rice KC, Negus SS. Maintenance on naltrexone+amphetamine decreases cocaine-vs.-food choice in male rhesus monkeys. Drug and Alcohol Dependence. 181: 85-93. PMID 29040826 DOI: 10.1016/J.Drugalcdep.2017.09.020  0.39
2017 Townsend EA, Naylor JE, Negus SS, Edwards SR, Qureshi HN, McLendon HW, McCurdy CR, Kapanda CN, do Carmo JM, da Silva FS, Hall JE, Sufka KJ, Freeman KB. Effects of nalfurafine on the reinforcing, thermal antinociceptive, and respiratory-depressant effects of oxycodone: modeling an abuse-deterrent opioid analgesic in rats. Psychopharmacology. PMID 28567699 DOI: 10.1007/S00213-017-4652-3  0.313
2017 Thomsen M, Barrett AC, Butler P, Negus SS, Caine SB. Effects of acute and chronic treatments with D2 and D3 receptor ligands on cocaine vs. food choice in rats. The Journal of Pharmacology and Experimental Therapeutics. PMID 28473458 DOI: 10.1124/jpet.117.241141  0.717
2017 Lazenka MF, Negus SS. Oral modafinil facilitates intracranial self-stimulation in rats: comparison with methylphenidate. Behavioural Pharmacology. 28: 318-322. PMID 28125506 DOI: 10.1097/FBP.0000000000000288  0.342
2016 Banks ML, Negus SS. Repeated 7-Day Treatment with the 5-HT2C Agonist Lorcaserin or the 5-HT2A Antagonist Pimavanserin Alone or in Combination Fails to Reduce Cocaine vs. Food Choice in Male Rhesus Monkeys. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 27857126 DOI: 10.1038/npp.2016.259  0.348
2016 Smith DA, Negus SS, Poklis JL, Blough BE, Banks ML. Cocaine-like discriminative stimulus effects of alpha-pyrrolidinovalerophenone, methcathinone and their 3,4-methylenedioxy or 4-methyl analogs in rhesus monkeys. Addiction Biology. PMID 27060605 DOI: 10.1111/adb.12399  0.32
2016 Banks ML, Bauer CT, Negus SS, Blough BE. Cocaine-like discriminative stimulus effects of phendimetrazine and phenmetrazine in rats. Behavioural Pharmacology. PMID 26866973 DOI: 10.1097/FBP.0000000000000225  0.343
2016 Leitl MD, Negus SS. Pharmacological modulation of neuropathic pain-related depression of behavior: effects of morphine, ketoprofen, bupropion and [INCREMENT]9-tetrahydrocannabinol on formalin-induced depression of intracranial self-stimulation in rats. Behavioural Pharmacology. 27: 364-76. PMID 26588213 DOI: 10.1097/FBP.0000000000000207  0.311
2015 Miller LL, Altarifi AA, Negus SS. Effects of repeated morphine on intracranial self-stimulation in male rats in the absence or presence of a noxious pain stimulus. Experimental and Clinical Psychopharmacology. 23: 405-14. PMID 26375515 DOI: 10.1037/pha0000042  0.325
2015 Banks ML, Hutsell BA, Schwienteck KL, Negus SS. Use of Preclinical Drug vs. Food Choice Procedures to Evaluate Candidate Medications for Cocaine Addiction. Current Treatment Options in Psychiatry. 2: 136-150. PMID 26009706 DOI: 10.1007/s40501-015-0042-9  0.312
2015 Lazenka MF, Moeller FG, Negus SS. Effects of caffeine and its metabolite paraxanthine on intracranial self-stimulation in male rats. Experimental and Clinical Psychopharmacology. 23: 71-80. PMID 25844631 DOI: 10.1037/Pha0000012  0.332
2015 Kolanos R, Partilla JS, Baumann MH, Hutsell BA, Banks ML, Negus SS, Glennon RA. Stereoselective Actions of Methylenedioxypyrovalerone (MDPV) To Inhibit Dopamine and Norepinephrine Transporters and Facilitate Intracranial Self-Stimulation in Rats. Acs Chemical Neuroscience. 6: 771-7. PMID 25688761 DOI: 10.1021/Acschemneuro.5B00006  0.3
2015 Banks ML, Hutsell BA, Blough BE, Poklis JL, Negus SS. Preclinical Assessment of Lisdexamfetamine as an Agonist Medication Candidate for Cocaine Addiction: Effects in Rhesus Monkeys Trained to Discriminate Cocaine or to Self-Administer Cocaine in a Cocaine Versus Food Choice Procedure. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 18. PMID 25618405 DOI: 10.1093/ijnp/pyv009  0.332
2015 Hutsell BA, Cheng K, Rice KC, Negus SS, Banks ML. Effects of the kappa opioid receptor antagonist nor-binaltorphimine (nor-BNI) on cocaine versus food choice and extended-access cocaine intake in rhesus monkeys. Addiction Biology. PMID 25581305 DOI: 10.1111/Adb.12206  0.326
2015 Negus SS, Henningfield J. Agonist Medications for the Treatment of Cocaine Use Disorder. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 40: 1815-25. PMID 25563633 DOI: 10.1038/Npp.2014.322  0.328
2015 Altarifi AA, Negus SS. Differential tolerance to morphine antinociception in assays of pain-stimulated vs. pain-depressed behavior in rats. European Journal of Pharmacology. 748: 76-82. PMID 25530266 DOI: 10.1016/j.ejphar.2014.12.011  0.309
2015 Altarifi AA, Rice KC, Negus SS. Effects of μ-opioid receptor agonists in assays of acute pain-stimulated and pain-depressed behavior in male rats: role of μ-agonist efficacy and noxious stimulus intensity. The Journal of Pharmacology and Experimental Therapeutics. 352: 208-17. PMID 25406170 DOI: 10.1124/Jpet.114.219873  0.311
2014 Hillhouse TM, Porter JH, Negus SS. Comparison of antidepressant-like and abuse-related effects of phencyclidine in rats. Drug Development Research. 75: 479-88. PMID 25315690 DOI: 10.1002/Ddr.21228  0.301
2014 Leitl MD, Onvani S, Bowers MS, Cheng K, Rice KC, Carlezon WA, Banks ML, Negus SS. Pain-related depression of the mesolimbic dopamine system in rats: expression, blockade by analgesics, and role of endogenous κ-opioids. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 39: 614-24. PMID 24008352 DOI: 10.1038/Npp.2013.236  0.307
2013 Banks ML, Blough BE, Fennell TR, Snyder RW, Negus SS. Effects of phendimetrazine treatment on cocaine vs food choice and extended-access cocaine consumption in rhesus monkeys. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 38: 2698-707. PMID 23893022 DOI: 10.1038/npp.2013.180  0.317
2013 Altarifi AA, Rice KC, Negus SS. Abuse-related effects of μ-opioid analgesics in an assay of intracranial self-stimulation in rats: Modulation by chronic morphine exposure Behavioural Pharmacology. 24: 459-470. PMID 23881045 DOI: 10.1097/Fbp.0B013E328364C0Bd  0.334
2013 Kaufman MJ, Janes AC, Frederick Bd, Brimson-Théberge M, Tong Y, McWilliams SB, Bear A, Gillis TE, Schrode KM, Renshaw PF, Negus SS. A method for conducting functional MRI studies in alert nonhuman primates: initial results with opioid agonists in male cynomolgus monkeys. Experimental and Clinical Psychopharmacology. 21: 323-31. PMID 23773004 DOI: 10.1037/A0033062  0.304
2013 Banks ML, Blough BE, Negus SS. Effects of 14-day treatment with the schedule III anorectic phendimetrazine on choice between cocaine and food in rhesus monkeys. Drug and Alcohol Dependence. 131: 204-13. PMID 23726979 DOI: 10.1016/j.drugalcdep.2013.05.005  0.345
2013 Thomsen M, Barrett AC, Negus SS, Caine SB. Cocaine versus food choice procedure in rats: environmental manipulations and effects of amphetamine. Journal of the Experimental Analysis of Behavior. 99: 211-33. PMID 23319458 DOI: 10.1002/Jeab.15  0.706
2013 Banks ML, Blough BE, Fennell TR, Snyder RW, Negus SS. Role of phenmetrazine as an active metabolite of phendimetrazine: evidence from studies of drug discrimination and pharmacokinetics in rhesus monkeys. Drug and Alcohol Dependence. 130: 158-66. PMID 23211394 DOI: 10.1016/j.drugalcdep.2012.10.026  0.362
2013 Negus SS, Banks ML. Medications development for opioid abuse. Cold Spring Harbor Perspectives in Medicine. 3: a012104. PMID 23125072 DOI: 10.1101/cshperspect.a012104  0.315
2013 Banks ML, Blough BE, Negus SS. Interaction between behavioral and pharmacological treatment strategies to decrease cocaine choice in rhesus monkeys. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 38: 395-404. PMID 22968813 DOI: 10.1038/npp.2012.193  0.305
2012 Aceto MD, Harris LS, Negus SS, Banks ML, Hughes LD, Akgün E, Portoghese PS. MDAN-21: A Bivalent Opioid Ligand Containing mu-Agonist and Delta-Antagonist Pharmacophores and Its Effects in Rhesus Monkeys. International Journal of Medicinal Chemistry. 2012: 327257. PMID 25954526 DOI: 10.1155/2012/327257  0.348
2012 Yekkirala AS, Banks ML, Lunzer MM, Negus SS, Rice KC, Portoghese PS. Clinically employed opioid analgesics produce antinociception via μ-δ opioid receptor heteromers in Rhesus monkeys. Acs Chemical Neuroscience. 3: 720-7. PMID 23019498 DOI: 10.1021/Cn300049M  0.301
2012 Altarifi AA, Miller LL, Negus SS. Role of µ-opioid receptor reserve and µ-agonist efficacy as determinants of the effects of µ-agonists on intracranial self-stimulation in rats. Behavioural Pharmacology. 23: 678-92. PMID 22914074 DOI: 10.1097/FBP.0b013e328358593c  0.32
2012 Negus SS, Morrissey EM, Folk JE, Rice KC. Interaction between Mu and Delta Opioid Receptor Agonists in an Assay of Capsaicin-Induced Thermal Allodynia in Rhesus Monkeys. Pain Research and Treatment. 2012: 867067. PMID 22666579 DOI: 10.1155/2012/867067  0.343
2012 Negus SS, O'Connell R, Morrissey E, Cheng K, Rice KC. Effects of peripherally restricted κ opioid receptor agonists on pain-related stimulation and depression of behavior in rats Journal of Pharmacology and Experimental Therapeutics. 340: 501-509. PMID 22128346 DOI: 10.1124/Jpet.111.186783  0.317
2011 Banks ML, Blough BE, Negus SS. Effects of monoamine releasers with varying selectivity for releasing dopamine/norepinephrine versus serotonin on choice between cocaine and food in rhesus monkeys. Behavioural Pharmacology. 22: 824-36. PMID 22015808 DOI: 10.1097/FBP.0b013e32834d63ac  0.322
2011 Altarifi AA, Negus SS. Some determinants of morphine effects on intracranial self-stimulation in rats: dose, pretreatment time, repeated treatment, and rate dependence. Behavioural Pharmacology. 22: 663-73. PMID 21921839 DOI: 10.1097/FBP.0b013e32834aff54  0.332
2011 Banks ML, Roma PG, Folk JE, Rice KC, Negus SS. Effects of the delta-opioid agonist SNC80 on the abuse liability of methadone in rhesus monkeys: a behavioral economic analysis. Psychopharmacology. 216: 431-9. PMID 21369752 DOI: 10.1007/S00213-011-2235-2  0.416
2010 Newman JL, Negus SS, Lozama A, Prisinzano TE, Mello NK. Behavioral evaluation of modafinil and the abuse-related effects of cocaine in rhesus monkeys. Experimental and Clinical Psychopharmacology. 18: 395-408. PMID 20939643 DOI: 10.1037/A0021042  0.364
2010 Banks ML, Folk JE, Rice KC, Negus SS. Selective enhancement of fentanyl-induced antinociception by the delta agonist SNC162 but not by ketamine in rhesus monkeys: Further evidence supportive of delta agonists as candidate adjuncts to mu opioid analgesics. Pharmacology, Biochemistry, and Behavior. 97: 205-12. PMID 20678514 DOI: 10.1016/J.Pbb.2010.07.019  0.358
2010 Banks ML, Rice KC, Negus SS. Antinociceptive interactions between Mu-opioid receptor agonists and the serotonin uptake inhibitor clomipramine in rhesus monkeys: role of Mu agonist efficacy. The Journal of Pharmacology and Experimental Therapeutics. 335: 497-505. PMID 20675432 DOI: 10.1124/Jpet.110.169276  0.36
2010 Negus SS, Morrissey EM, Rosenberg M, Cheng K, Rice KC. Effects of kappa opioids in an assay of pain-depressed intracranial self-stimulation in rats Psychopharmacology. 209: 149-159. PMID 20101391 DOI: 10.1007/S00213-009-1770-6  0.328
2010 Negus SS, Banks ML, Folk JE, Rice KC. Modulation of delta opioid agonist-induced antinociception by repeated morphine pretreatment in rhesus monkeys. Life Sciences. 86: 385-92. PMID 20096291 DOI: 10.1016/J.Lfs.2010.01.006  0.361
2010 Banks ML, Negus SS. Effects of extended cocaine access and cocaine withdrawal on choice between cocaine and food in rhesus monkeys. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 35: 493-504. PMID 19776729 DOI: 10.1038/npp.2009.154  0.34
2009 Do Carmo GP, Folk JE, Rice KC, Chartoff E, Carlezon WA, Negus SS. The selective non-peptidic delta opioid agonist SNC80 does not facilitate intracranial self-stimulation in rats. European Journal of Pharmacology. 604: 58-65. PMID 19133255 DOI: 10.1016/J.Ejphar.2008.12.021  0.357
2009 Negus SS, Bear AE, Folk JE, Rice KC. Role of delta opioid efficacy as a determinant of mu/delta opioid interactions in rhesus monkeys. European Journal of Pharmacology. 602: 92-100. PMID 19027735 DOI: 10.1016/J.Ejphar.2008.11.004  0.345
2009 Negus SS, Rice KC. Mechanisms of withdrawal-associated increases in heroin self-administration: Pharmacologic modulation of heroin vs food choice in heroin-dependent rhesus monkeys Neuropsychopharmacology. 34: 899-911. PMID 18704098 DOI: 10.1038/Npp.2008.127  0.36
2008 Negus SS, Schrode K, Stevenson GW. Micro/kappa opioid interactions in rhesus monkeys: implications for analgesia and abuse liability. Experimental and Clinical Psychopharmacology. 16: 386-99. PMID 18837635 DOI: 10.1037/a0013088  0.403
2008 Do Carmo GP, Polt R, Bilsky EJ, Rice KC, Negus SS. Behavioral pharmacology of the mu/delta opioid glycopeptide MMP2200 in rhesus monkeys. The Journal of Pharmacology and Experimental Therapeutics. 326: 939-48. PMID 18511649 DOI: 10.1124/Jpet.108.138180  0.337
2008 Kimmel HL, Negus SS, Wilcox KM, Ewing SB, Stehouwer J, Goodman MM, Votaw JR, Mello NK, Carroll FI, Howell LL. Relationship between rate of drug uptake in brain and behavioral pharmacology of monoamine transporter inhibitors in rhesus monkeys. Pharmacology, Biochemistry, and Behavior. 90: 453-62. PMID 18468667 DOI: 10.1016/J.Pbb.2008.03.032  0.323
2008 Mello NK, Negus SS, Knudson IM, Kelly M, Mendelson JH. Effects of estradiol on cocaine self-administration and cocaine discrimination by female rhesus monkeys. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 33: 783-95. PMID 17507915 DOI: 10.1038/Sj.Npp.1301451  0.339
2007 Schindler CW, Graczyk Z, Gilman JP, Negus SS, Bergman J, Mello NK, Goldberg SR. Effects of kappa opioid agonists alone and in combination with cocaine on heart rate and blood pressure in conscious squirrel monkeys. European Journal of Pharmacology. 576: 107-13. PMID 17707792 DOI: 10.1016/J.Ejphar.2007.07.053  0.399
2007 Zernig G, Ahmed SH, Cardinal RN, Morgan D, Acquas E, Foltin RW, Vezina P, Negus SS, Crespo JA, Stöckl P, Grubinger P, Madlung E, Haring C, Kurz M, Saria A. Explaining the escalation of drug use in substance dependence: models and appropriate animal laboratory tests. Pharmacology. 80: 65-119. PMID 17570954 DOI: 10.1159/000103923  0.347
2007 Mello NK, Negus SS. Effects of d-amphetamine and buprenorphine combinations on speedball (cocaine+heroin) self-administration by rhesus monkeys. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 32: 1985-94. PMID 17228335 DOI: 10.1038/Sj.Npp.1301319  0.325
2006 Mello NK, Negus SS, Rice KC, Mendelson JH. Effects of the CRF1 antagonist antalarmin on cocaine self-administration and discrimination in rhesus monkeys. Pharmacology, Biochemistry, and Behavior. 85: 744-51. PMID 17182090 DOI: 10.1016/J.Pbb.2006.11.008  0.34
2006 Do Carmo GP, Mello NK, Rice KC, Folk JE, Negus SS. Effects of the selective delta opioid agonist SNC80 on cocaine- and food-maintained responding in rhesus monkeys. European Journal of Pharmacology. 547: 92-100. PMID 16934797 DOI: 10.1016/J.Ejphar.2006.06.075  0.361
2005 Mathews JL, Peng X, Xiong W, Zhang A, Negus SS, Neumeyer JL, Bidlack JM. Characterization of a novel bivalent morphinan possessing kappa agonist and micro agonist/antagonist properties. The Journal of Pharmacology and Experimental Therapeutics. 315: 821-7. PMID 16076937 DOI: 10.1124/jpet.105.084343  0.321
2005 Barrett AC, Negus SS, Mello NK, Caine SB. Effect of GABA agonists and GABA-A receptor modulators on cocaine- and food-maintained responding and cocaine discrimination in rats. The Journal of Pharmacology and Experimental Therapeutics. 315: 858-71. PMID 16033912 DOI: 10.1124/Jpet.105.086033  0.317
2005 Stevenson GW, Folk JE, Rice KC, Negus SS. Interactions between delta and mu opioid agonists in assays of schedule-controlled responding, thermal nociception, drug self-administration, and drug versus food choice in rhesus monkeys: studies with SNC80 [(+)-4-[(alphaR)-alpha-((2S,5R)-4-allyl-2,5-dimethyl-1-piperazinyl)-3-methoxybenzyl]-N,N-diethylbenzamide] and heroin. The Journal of Pharmacology and Experimental Therapeutics. 314: 221-31. PMID 15792997 DOI: 10.1124/Jpet.104.082685  0.377
2004 Stevenson GW, Wentland MP, Bidlack JM, Mello NK, Negus SS. Effects of the mixed-action kappa/mu opioid agonist 8-carboxamidocyclazocine on cocaine- and food-maintained responding in rhesus monkeys. European Journal of Pharmacology. 506: 133-41. PMID 15588733 DOI: 10.1016/J.Ejphar.2004.10.051  0.337
2004 Grabowski J, Shearer J, Merrill J, Negus SS. Agonist-like, replacement pharmacotherapy for stimulant abuse and dependence. Addictive Behaviors. 29: 1439-64. PMID 15345275 DOI: 10.1016/j.addbeh.2004.06.018  0.313
2004 Negus SS, Mello NK. Effects of chronic methadone treatment on cocaine- and food-maintained responding under second-order, progressive-ratio and concurrent-choice schedules in rhesus monkeys. Drug and Alcohol Dependence. 74: 297-309. PMID 15194208 DOI: 10.1016/J.Drugalcdep.2004.01.006  0.336
2004 Caine SB, Bowen CA, Yu G, Zuzga D, Negus SS, Mello NK. Effect of gonadectomy and gonadal hormone replacement on cocaine self-administration in female and male rats. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 29: 929-42. PMID 14735136 DOI: 10.1038/Sj.Npp.1300387  0.325
2003 Stevenson GW, Folk JE, Linsenmayer DC, Rice KC, Negus SS. Opioid interactions in rhesus monkeys: effects of delta + mu and delta + kappa agonists on schedule-controlled responding and thermal nociception. The Journal of Pharmacology and Experimental Therapeutics. 307: 1054-64. PMID 14557380 DOI: 10.1124/Jpet.103.056515  0.351
2003 Negus SS, Mello NK. Effects of chronic d-amphetamine treatment on cocaine- and food-maintained responding under a second-order schedule in rhesus monkeys. Drug and Alcohol Dependence. 70: 39-52. PMID 12681524 DOI: 10.1016/S0376-8716(02)00339-3  0.369
2003 Negus SS, Brandt MR, Gatch MB, Mello NK. Effects of heroin and its metabolites on schedule-controlled responding and thermal nociception in rhesus monkeys: sensitivity to antagonism by quadazocine, naltrindole and beta-funaltrexamine. Drug and Alcohol Dependence. 70: 17-27. PMID 12681522 DOI: 10.1016/S0376-8716(02)00331-9  0.34
2003 Negus SS, Mello NK. Effects of chronic d-amphetamine treatment on cocaine- and food-maintained responding under a progressive-ratio schedule in rhesus monkeys. Psychopharmacology. 167: 324-32. PMID 12652348 DOI: 10.1007/s00213-003-1409-y  0.346
2003 Bowen CA, Negus SS, Zong R, Neumeyer JL, Bidlack JM, Mello NK. Effects of mixed-action kappa/mu opioids on cocaine self-administration and cocaine discrimination by rhesus monkeys. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 28: 1125-39. PMID 12637953 DOI: 10.1038/Sj.Npp.1300105  0.385
2002 Negus SS, Mello NK, Linsenmayer DC, Jones RM, Portoghese PS. Kappa opioid antagonist effects of the novel kappa antagonist 5'-guanidinonaltrindole (GNTI) in an assay of schedule-controlled behavior in rhesus monkeys. Psychopharmacology. 163: 412-9. PMID 12373442 DOI: 10.1007/S00213-002-1038-X  0.368
2002 Bowen CA, Fischer BD, Mello NK, Negus SS. Antagonism of the antinociceptive and discriminative stimulus effects of heroin and morphine by 3-methoxynaltrexone and naltrexone in rhesus monkeys. The Journal of Pharmacology and Experimental Therapeutics. 302: 264-73. PMID 12065726 DOI: 10.1124/Jpet.302.1.264  0.349
2002 Caine SB, Negus SS, Mello NK, Patel S, Bristow L, Kulagowski J, Vallone D, Saiardi A, Borrelli E. Role of dopamine D2-like receptors in cocaine self-administration: studies with D2 receptor mutant mice and novel D2 receptor antagonists. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 2977-88. PMID 11923462 DOI: 10.1523/Jneurosci.22-07-02977.2002  0.328
2002 Negus SS, Mello NK. Effects of mu-opioid agonists on cocaine- and food-maintained responding and cocaine discrimination in rhesus monkeys: role of mu-agonist efficacy. The Journal of Pharmacology and Experimental Therapeutics. 300: 1111-21. PMID 11861822 DOI: 10.1124/Jpet.300.3.1111  0.398
2002 Bowen CA, Negus SS, Kelly M, Mello NK. The effects of heroin on prolactin levels in male rhesus monkeys: use of cumulative-dosing procedures. Psychoneuroendocrinology. 27: 319-36. PMID 11818169 DOI: 10.1016/S0306-4530(01)00053-1  0.363
2001 Negus SS, Pope HG, Kanayama G, Wines JD, Fischer BD. Lack of evidence for opioid tolerance or dependence in rhesus monkeys following high-dose anabolic-androgenic steroid administration. Psychoneuroendocrinology. 26: 789-96. PMID 11585679 DOI: 10.1016/S0306-4530(01)00028-2  0.341
2000 Mello NK, Negus SS. Interactions between kappa opioid agonists and cocaine. Preclinical studies. Annals of the New York Academy of Sciences. 909: 104-32. PMID 10911926 DOI: 10.1111/J.1749-6632.2000.Tb06678.X  0.385
1999 Negus SS, Mello NK. Effects of kappa opioid agonists on the discriminative stimulus effects of cocaine in rhesus monkeys. Experimental and Clinical Psychopharmacology. 7: 307-17. PMID 10609965 DOI: 10.1037//1064-1297.7.4.307  0.348
1999 Gatch MB, Negus SS, Mello NK. Antinociceptive effects of cocaine in rhesus monkeys. Pharmacology, Biochemistry, and Behavior. 62: 291-7. PMID 9972696 DOI: 10.1016/S0091-3057(98)00163-4  0.389
1998 Lamas X, Negus SS, Gatch MB, Mello NK. Effects of heroin/cocaine combinations in rats trained to discriminate heroin or cocaine from saline. Pharmacology, Biochemistry, and Behavior. 60: 357-64. PMID 9632217 DOI: 10.1016/S0091-3057(98)00021-5  0.329
1996 Gatch MB, Liguori A, Negus SS, Mello NK, Bergman J, Liguori T. Naloxonazine antagonism of levorphanol-induced antinociception and respiratory depression in rhesus monkeys. European Journal of Pharmacology. 298: 31-6. PMID 8867916 DOI: 10.1016/0014-2999(95)00769-5  0.348
1990 Picker MJ, Negus SS, Craft RM. Butorphanol's efficacy at mu and kappa opioid receptors: inferences based on the schedule-controlled behavior of nontolerant and morphine-tolerant rats and on the responding of rats under a drug discrimination procedure. Pharmacology, Biochemistry, and Behavior. 36: 563-8. PMID 2165617 DOI: 10.1016/0091-3057(90)90256-H  0.325
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