Jürgen Wess - Publications

NIDDK, National Institutes of Health 

85 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Pydi SP, Jain S, Barella LF, Zhu L, Sakamoto W, Meister J, Wang L, Lu H, Cui Y, Gavrilova O, Wess J. β-arrestin-1 suppresses myogenic reprogramming of brown fat to maintain euglycemia. Science Advances. 6: eaba1733. PMID 32548266 DOI: 10.1126/sciadv.aba1733  0.32
2020 Pydi SP, Cui Z, He Z, Barella LF, Pham J, Cui Y, Oberlin DJ, Egritag HE, Urs N, Gavrilova O, Schwartz GJ, Buettner C, Williams KW, Wess J. Beneficial metabolic role of β-arrestin-1 expressed by AgRP neurons. Science Advances. 6: eaaz1341. PMID 32537493 DOI: 10.1126/sciadv.aaz1341  0.32
2020 Wang L, Pydi SP, Zhu L, Barella LF, Cui Y, Gavrilova O, Bence KK, Vernochet C, Wess J. Adipocyte G signaling is essential for maintaining whole-body glucose homeostasis and insulin sensitivity. Nature Communications. 11: 2995. PMID 32532984 DOI: 10.1038/s41467-020-16756-x  0.32
2019 Burczyk MS, Burkhalter MD, Tena TC, Grisanti LA, Kauk M, Matysik S, Donow C, Kustermann M, Rothe M, Cui Y, Raad F, Laue S, Moretti A, Zimmermann WH, Wess J, et al. Muscarinic receptors promote pacemaker fate at the expense of secondary conduction system tissue in zebrafish. Jci Insight. 4. PMID 31619590 DOI: 10.1172/jci.insight.121971  0.32
2019 Wang L, Pydi SP, Cui Y, Zhu L, Meister J, Gavrilova O, Berdeaux R, Fortin JP, Bence KK, Vernochet C, Wess J. Selective activation of G signaling in adipocytes causes striking metabolic improvements in mice. Molecular Metabolism. PMID 31272886 DOI: 10.1016/j.molmet.2019.06.018  0.32
2019 Pydi SP, Jain S, Tung W, Cui Y, Zhu L, Sakamoto W, Jain S, Abel BS, Skarulis MC, Liu J, Huynh T, Pacak K, Caron MG, Gavrilova O, Finkel T, ... Wess J, et al. Adipocyte β-arrestin-2 is essential for maintaining whole body glucose and energy homeostasis. Nature Communications. 10: 2936. PMID 31270323 DOI: 10.1038/s41467-019-11003-4  0.32
2019 Barella LF, Rossi M, Zhu L, Cui Y, Mei FC, Cheng X, Chen W, Gurevich VV, Wess J. β-Cell-intrinsic β-arrestin 1 signaling enhances sulfonylurea-induced insulin secretion. The Journal of Clinical Investigation. 130. PMID 31184597 DOI: 10.1172/JCI126309  0.32
2019 Zhu L, Dattaroy D, Pham J, Wang L, Barella LF, Cui Y, Wilkins KJ, Roth BL, Hochgeschwender U, Matschinsky FM, Kaestner KH, Doliba NM, Wess J. Intra-islet glucagon signaling is critical for maintaining glucose homeostasis. Jci Insight. 5. PMID 31012868 DOI: 10.1172/jci.insight.127994  0.32
2018 Rossi M, Zhu L, McMillin SM, Pydi SP, Jain S, Wang L, Cui Y, Lee RJ, Cohen AH, Kaneto H, Birnbaum MJ, Ma Y, Rotman Y, Liu J, Cyphert TJ, ... ... Wess J, et al. Hepatic Gi signaling regulates whole-body glucose homeostasis. The Journal of Clinical Investigation. PMID 29337301 DOI: 10.1172/JCI94505  0.32
2017 Moehle MS, Pancani T, Byun N, Yohn SE, Wilson GH, Dickerson JW, Remke DH, Xiang Z, Niswender CM, Wess J, Jones CK, Lindsley CW, Rook JM, Conn PJ. Cholinergic Projections to the Substantia Nigra Pars Reticulata Inhibit Dopamine Modulation of Basal Ganglia through the M4 Muscarinic Receptor. Neuron. 96: 1358-1372.e4. PMID 29268098 DOI: 10.1016/j.neuron.2017.12.008  0.44
2017 Gould RW, Grannan MD, Gunter BW, Ball J, Bubser M, Bridges TM, Wess J, Wood MW, Brandon NJ, Duggan ME, Niswender CM, Lindsley CW, Conn PJ, Jones CK. Cognitive enhancement and antipsychotic-like activity following repeated dosing with the selective M4 PAM VU0467154. Neuropharmacology. PMID 28729220 DOI: 10.1016/j.neuropharm.2017.07.013  0.44
2017 Zhu L, Rossi M, Cui Y, Lee RJ, Sakamoto W, Perry NA, Urs NM, Caron MG, Gurevich VV, Godlewski G, Kunos G, Chen M, Chen W, Wess J. Hepatic β-arrestin 2 is essential for maintaining euglycemia. The Journal of Clinical Investigation. PMID 28650340 DOI: 10.1172/JCI92913  0.32
2017 Zhu L, Almaça J, Dadi PK, Hong H, Sakamoto W, Rossi M, Lee RJ, Vierra NC, Lu H, Cui Y, McMillin SM, Perry NA, Gurevich VV, Lee A, Kuo B, ... ... Wess J, et al. β-arrestin-2 is an essential regulator of pancreatic β-cell function under physiological and pathophysiological conditions. Nature Communications. 8: 14295. PMID 28145434 DOI: 10.1038/ncomms14295  0.32
2016 Foster DJ, Wilson JM, Remke DH, Mahmood MS, Uddin MJ, Wess J, Patel S, Marnett LJ, Niswender CM, Jones CK, Xiang Z, Lindsley CW, Rook JM, Conn PJ. Antipsychotic-like Effects of M4 Positive Allosteric Modulators Are Mediated by CB2 Receptor-Dependent Inhibition of Dopamine Release. Neuron. PMID 27618677 DOI: 10.1016/j.neuron.2016.08.017  0.44
2016 Shen W, Plotkin JL, Francardo V, Ko WK, Xie Z, Li Q, Fieblinger T, Wess J, Neubig RR, Lindsley CW, Conn PJ, Greengard P, Bezard E, Cenci MA, Surmeier DJ. M4 Muscarinic Receptor Signaling Ameliorates Striatal Plasticity Deficits in Models of L-DOPA-Induced Dyskinesia. Neuron. 90: 1139. PMID 27253449 DOI: 10.1016/j.neuron.2016.05.017  0.44
2016 Klepac K, Kilić A, Gnad T, Brown LM, Herrmann B, Wilderman A, Balkow A, Glöde A, Simon K, Lidell ME, Betz MJ, Enerbäck S, Wess J, Freichel M, Blüher M, et al. The Gq signalling pathway inhibits brown and beige adipose tissue. Nature Communications. 7: 10895. PMID 26955961 DOI: 10.1038/ncomms10895  0.64
2016 Nakajima K, Cui Z, Li C, Meister J, Cui Y, Fu O, Smith AS, Jain S, Lowell BB, Krashes MJ, Wess J. Corrigendum: Gs-coupled GPCR signalling in AgRP neurons triggers sustained increase in food intake. Nature Communications. 7: 11019. PMID 26936677 DOI: 10.1038/ncomms11019  0.32
2016 Nakajima K, Cui Z, Li C, Meister J, Cui Y, Fu O, Smith AS, Jain S, Lowell BB, Krashes MJ, Wess J. Gs-coupled GPCR signalling in AgRP neurons triggers sustained increase in food intake. Nature Communications. 7: 10268. PMID 26743492 DOI: 10.1038/ncomms10268  0.64
2015 Rossi M, Ruiz de Azua I, Barella LF, Sakamoto W, Zhu L, Cui Y, Lu H, Rebholz H, Matschinsky FM, Doliba NM, Butcher AJ, Tobin AB, Wess J. CK2 acts as a potent negative regulator of receptor-mediated insulin release in vitro and in vivo. Proceedings of the National Academy of Sciences of the United States of America. PMID 26598688 DOI: 10.1073/pnas.1519430112  0.32
2015 Shen W, Plotkin JL, Francardo V, Ko WK, Xie Z, Li Q, Fieblinger T, Wess J, Neubig RR, Lindsley CW, Conn PJ, Greengard P, Bezard E, Cenci MA, Surmeier DJ. M4 Muscarinic Receptor Signaling Ameliorates Striatal Plasticity Deficits in Models of L-DOPA-Induced Dyskinesia. Neuron. 88: 762-773. PMID 26590347 DOI: 10.1016/j.neuron.2015.10.039  0.64
2015 Shin JH, Adrover MF, Wess J, Alvarez VA. Muscarinic regulation of dopamine and glutamate transmission in the nucleus accumbens. Proceedings of the National Academy of Sciences of the United States of America. PMID 26080439 DOI: 10.1073/pnas.1508846112  0.64
2014 Trivellin G, Daly AF, Faucz FR, Yuan B, Rostomyan L, Larco DO, Schernthaner-Reiter MH, Szarek E, Leal LF, Caberg JH, Castermans E, Villa C, Dimopoulos A, Chittiboina P, Xekouki P, ... ... Wess J, et al. Gigantism and acromegaly due to Xq26 microduplications and GPR101 mutation. The New England Journal of Medicine. 371: 2363-74. PMID 25470569 DOI: 10.1056/NEJMoa1408028  0.64
2014 Bubser M, Bridges TM, Dencker D, Gould RW, Grannan M, Noetzel MJ, Lamsal A, Niswender CM, Daniels JS, Poslusney MS, Melancon BJ, Tarr JC, Byers FW, Wess J, Duggan ME, et al. Selective activation of M4 muscarinic acetylcholine receptors reverses MK-801-induced behavioral impairments and enhances associative learning in rodents. Acs Chemical Neuroscience. 5: 920-42. PMID 25137629 DOI: 10.1021/cn500128b  0.64
2014 Kruse AC, Kobilka BK, Gautam D, Sexton PM, Christopoulos A, Wess J. Muscarinic acetylcholine receptors: novel opportunities for drug development. Nature Reviews. Drug Discovery. 13: 549-60. PMID 24903776 DOI: 10.1038/nrd4295  0.64
2014 Chen SR, Chen H, Yuan WX, Wess J, Pan HL. Differential regulation of primary afferent input to spinal cord by muscarinic receptor subtypes delineated using knockout mice. The Journal of Biological Chemistry. 289: 14321-30. PMID 24695732 DOI: 10.1074/jbc.M114.550384  0.64
2014 Kruse AC, Hu J, Kobilka BK, Wess J. Muscarinic acetylcholine receptor X-ray structures: potential implications for drug development. Current Opinion in Pharmacology. 16: 24-30. PMID 24662799 DOI: 10.1016/j.coph.2014.02.006  0.64
2014 Nichols JL, Gladwell W, Verhein KC, Cho HY, Wess J, Suzuki O, Wiltshire T, Kleeberger SR. Genome-wide association mapping of acute lung injury in neonatal inbred mice. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 28: 2538-50. PMID 24571919 DOI: 10.1096/fj.13-247221  0.64
2014 Byun NE, Grannan M, Bubser M, Barry RL, Thompson A, Rosanelli J, Gowrishankar R, Kelm ND, Damon S, Bridges TM, Melancon BJ, Tarr JC, Brogan JT, Avison MJ, Deutch AY, ... Wess J, et al. Antipsychotic drug-like effects of the selective M4 muscarinic acetylcholine receptor positive allosteric modulator VU0152100. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 39: 1578-93. PMID 24442096 DOI: 10.1038/npp.2014.2  0.64
2014 Kruse AC, Li J, Hu J, Kobilka BK, Wess J. Novel insights into M3 muscarinic acetylcholine receptor physiology and structure. Journal of Molecular Neuroscience : Mn. 53: 316-23. PMID 24068573 DOI: 10.1007/s12031-013-0127-0  0.64
2013 Kruse AC, Ring AM, Manglik A, Hu J, Hu K, Eitel K, Hübner H, Pardon E, Valant C, Sexton PM, Christopoulos A, Felder CC, Gmeiner P, Steyaert J, Weis WI, ... ... Wess J, et al. Activation and allosteric modulation of a muscarinic acetylcholine receptor. Nature. 504: 101-6. PMID 24256733 DOI: 10.1038/nature12735  0.64
2013 Hu J, Hu K, Liu T, Stern MK, Mistry R, Challiss RA, Costanzi S, Wess J. Novel structural and functional insights into M3 muscarinic receptor dimer/oligomer formation. The Journal of Biological Chemistry. 288: 34777-90. PMID 24133207 DOI: 10.1074/jbc.M113.503714  0.64
2013 Kruse AC, Weiss DR, Rossi M, Hu J, Hu K, Eitel K, Gmeiner P, Wess J, Kobilka BK, Shoichet BK. Muscarinic receptors as model targets and antitargets for structure-based ligand discovery. Molecular Pharmacology. 84: 528-40. PMID 23887926 DOI: 10.1124/mol.113.087551  0.64
2013 Li JH, Jain S, McMillin SM, Cui Y, Gautam D, Sakamoto W, Lu H, Jou W, McGuinness OP, Gavrilova O, Wess J. A novel experimental strategy to assess the metabolic effects of selective activation of a Gq- coupled receptor in hepatocytes in vivo Endocrinology. 154: 3539-3551. PMID 23861369 DOI: 10.1210/en.2012-2127  0.64
2013 Ferguson SM, Phillips PE, Roth BL, Wess J, Neumaier JF. Direct-pathway striatal neurons regulate the retention of decision-making strategies. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 11668-76. PMID 23843534 DOI: 10.1523/JNEUROSCI.4783-12.2013  0.64
2013 Nakajima K, Jain S, de Azua IR, McMillin SM, Rossi M, Wess J. Minireview: Novel aspects of M3 muscarinic receptor signaling in pancreatic β-cells Molecular Endocrinology. 27: 1208-1216. PMID 23820900 DOI: 10.1210/me.2013-1084  0.64
2013 Jain S, De Azua IR, Lu H, White MF, Guettier JM, Wess J. Chronic activation of a designer Gq-coupled receptor improves β cell function Journal of Clinical Investigation. 123: 1750-1762. PMID 23478411 DOI: 10.1172/JCI66432  0.64
2013 Arteaga-Solis E, Zee T, Emala CW, Vinson C, Wess J, Karsenty G. Inhibition of leptin regulation of parasympathetic signaling as a cause of extreme body weight-associated asthma. Cell Metabolism. 17: 35-48. PMID 23312282 DOI: 10.1016/j.cmet.2012.12.004  0.64
2013 Farrell MS, Pei Y, Wan Y, Yadav PN, Daigle TL, Urban DJ, Lee HM, Sciaky N, Simmons A, Nonneman RJ, Huang XP, Hufeisen SJ, Guettier JM, Moy SS, Wess J, et al. A Gαs DREADD mouse for selective modulation of cAMP production in striatopallidal neurons. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 38: 854-62. PMID 23303063 DOI: 10.1038/npp.2012.251  0.64
2012 Kohlmeier KA, Ishibashi M, Wess J, Bickford ME, Leonard CS. Knockouts reveal overlapping functions of M(2) and M(4) muscarinic receptors and evidence for a local glutamatergic circuit within the laterodorsal tegmental nucleus. Journal of Neurophysiology. 108: 2751-66. PMID 22956788 DOI: 10.1152/jn.01120.2011  0.64
2012 De Azua IR, Nakajima KI, Rossi M, Cui Y, Jou W, Gavrilova O, Wess J. Spinophilin as a novel regulator of M3 muscarinic receptor-mediated insulin release in vitro and in vivo Faseb Journal. 26: 4275-4286. PMID 22730439 DOI: 10.1096/fj.12-204644  0.64
2012 Dencker D, Weikop P, Sørensen G, Woldbye DPD, Wörtwein G, Wess J, Fink-Jensen A. An allosteric enhancer of M4 muscarinic acetylcholine receptor function inhibits behavioral and neurochemical effects of cocaine Psychopharmacology. 224: 277-287. PMID 22648127 DOI: 10.1007/s00213-012-2751-8  0.68
2012 Dencker D, Thomsen M, Wörtwein G, Weikop P, Cui Y, Jeon J, Wess J, Fink-Jensen A. Muscarinic Acetylcholine Receptor Subtypes as Potential Drug Targets for the Treatment of Schizophrenia, Drug Abuse and Parkinson's Disease. Acs Chemical Neuroscience. 3: 80-89. PMID 22389751 DOI: 10.1021/cn200110q  0.68
2012 Kruse AC, Hu J, Pan AC, Arlow DH, Rosenbaum DM, Rosemond E, Green HF, Liu T, Chae PS, Dror RO, Shaw DE, Weis WI, Wess J, Kobilka BK. Structure and dynamics of the M3 muscarinic acetylcholine receptor. Nature. 482: 552-6. PMID 22358844 DOI: 10.1038/nature10867  0.64
2012 Guo JD, Hazra R, Dabrowska J, Muly EC, Wess J, Rainnie DG. Presynaptic muscarinic M(2) receptors modulate glutamatergic transmission in the bed nucleus of the stria terminalis. Neuropharmacology. 62: 1671-83. PMID 22166222 DOI: 10.1016/j.neuropharm.2011.11.013  0.64
2012 Hu J, Thor D, Zhou Y, Liu T, Wang Y, McMillin SM, Mistry R, Challiss RAJ, Costanzi S, Wess J. Structural aspects of M3 muscarinic acetylcholine receptor dimer formation and activation Faseb Journal. 26: 604-616. PMID 22031716 DOI: 10.1096/fj.11-191510  0.64
2012 Thomsen M, Lindsley CW, Conn PJ, Wessell JE, Fulton BS, Wess J, Caine SB. Contribution of both M1 and M4 receptors to muscarinic agonist-mediated attenuation of the cocaine discriminative stimulus in mice Psychopharmacology. 220: 673-685. PMID 21964721 DOI: 10.1007/s00213-011-2516-9  0.64
2011 Regard JB, Cherman N, Palmer D, Kuznetsov SA, Celi FS, Guettier JM, Chen M, Bhattacharyya N, Wess J, Coughlin SR, Weinstein LS, Collins MT, Robey PG, Yang Y. Wnt/β-catenin signaling is differentially regulated by Gα proteins and contributes to fibrous dysplasia. Proceedings of the National Academy of Sciences of the United States of America. 108: 20101-6. PMID 22106277 DOI: 10.1073/pnas.1114656108  0.64
2011 Bartko SJ, Romberg C, White B, Wess J, Bussey TJ, Saksida LM. Intact attentional processing but abnormal responding in M1 muscarinic receptor-deficient mice using an automated touchscreen method. Neuropharmacology. 61: 1366-78. PMID 21903112 DOI: 10.1016/j.neuropharm.2011.08.023  0.64
2011 Raufman JP, Shant J, Xie G, Cheng K, Gao XM, Shiu B, Shah N, Drachenberg CB, Heath J, Wess J, Khurana S. Muscarinic receptor subtype-3 gene ablation and scopolamine butylbromide treatment attenuate small intestinal neoplasia in Apcmin/+ mice. Carcinogenesis. 32: 1396-402. PMID 21705482 DOI: 10.1093/carcin/bgr118  0.64
2011 McMillin SM, Heusel M, Liu T, Costanzi S, Wess J. Structural basis of M 3 muscarinic receptor dimer/oligomer formation Journal of Biological Chemistry. 286: 28584-28598. PMID 21685385 DOI: 10.1074/jbc.M111.259788  0.64
2011 Creson TK, Austin DR, Shaltiel G, Mccammon J, Wess J, Manji HK, Chen G. Lithium treatment attenuates muscarinic M1 receptor dysfunction Bipolar Disorders. 13: 238-249. PMID 21676127 DOI: 10.1111/j.1399-5618.2011.00915.x  0.64
2011 Dencker D, Wörtwein G, Weikop P, Jeon J, Thomsen M, Sager TN, Mørk A, Woldbye DPD, Wess J, Fink-Jensen A. Involvement of a subpopulation of neuronal M 4 muscarinic acetylcholine receptors in the antipsychotic-like effects of the M 1/M 4 preferring muscarinic receptor agonist xanomeline Journal of Neuroscience. 31: 5905-5908. PMID 21508215 DOI: 10.1523/JNEUROSCI.0370-11.2011  0.68
2011 Schmidt LS, Thomsen M, Weikop P, Dencker D, Wess J, Woldbye DPD, Wortwein G, Fink-Jensen A. Increased cocaine self-administration in M 4 muscarinic acetylcholine receptor knockout mice Psychopharmacology. 216: 367-378. PMID 21373792 DOI: 10.1007/s00213-011-2225-4  0.64
2011 Fink-Jensen A, Schmidt LS, Dencker D, Schülein C, Wess J, Wörtwein G, Woldbye DPD. Antipsychotic-induced catalepsy is attenuated in mice lacking the M 4 muscarinic acetylcholine receptor European Journal of Pharmacology. 656: 39-44. PMID 21269601 DOI: 10.1016/j.ejphar.2011.01.018  0.64
2011 Kupchik YM, Barchad-Avitzur O, Wess J, Ben-Chaim Y, Parnas I, Parnas H. A novel fast mechanism for GPCR-mediated signal transduction--control of neurotransmitter release. The Journal of Cell Biology. 192: 137-51. PMID 21200029 DOI: 10.1083/jcb.201007053  0.64
2011 Azua IRd, Gautam D, Guettier JM, Wess J. Novel insights into the function of β-cell M3 muscarinic acetylcholine receptors: Therapeutic implications Trends in Endocrinology and Metabolism. 22: 74-80. PMID 21106385 DOI: 10.1016/j.tem.2010.10.004  0.64
2011 Rosemond E, Rossi M, McMillin SM, Scarselli M, Donaldson JG, Wess J. Regulation of M3 muscarinic receptor expression and function by transmembrane protein 147 Molecular Pharmacology. 79: 251-261. PMID 21056967 DOI: 10.1124/mol.110.067363  0.64
2010 Kong KC, Butcher AJ, McWilliams P, Jones D, Wess J, Hamdan FF, Werry T, Rosethorne EM, Charlton SJ, Munson SE, Cragg HA, Smart AD, Tobin AB. M3-muscarinic receptor promotes insulin release via receptor phosphorylation/arrestin-dependent activation of protein kinase D1 Proceedings of the National Academy of Sciences of the United States of America. 107: 21181-21186. PMID 21078968 DOI: 10.1073/pnas.1011651107  0.64
2010 Chen SR, Chen H, Yuan WX, Wess J, Pan HL. Dynamic control of glutamatergic synaptic input in the spinal cord by muscarinic receptor subtypes defined using knockout mice. The Journal of Biological Chemistry. 285: 40427-37. PMID 20940295 DOI: 10.1074/jbc.M110.176966  0.64
2010 Gautam D, De Azua IR, Li JH, Guettier JM, Heard T, Cui Y, Lu H, Jou W, Gavrilova O, Zawalich WS, Wess J. Beneficial metabolic effects caused by persistent activation of β-cell M3 muscarinic acetylcholine receptors in transgenic mice Endocrinology. 151: 5185-5194. PMID 20843999 DOI: 10.1210/en.2010-0519  0.64
2010 Hu J, Wang Y, Zhang X, Lloyd JR, Li JH, Karpiak J, Costanzi S, Wess J. Structural basis of G protein-coupled receptor-G protein interactions. Nature Chemical Biology. 6: 541-8. PMID 20512139 DOI: 10.1038/nchembio.385  0.64
2010 Maison SF, Liu XP, Vetter DE, Eatock RA, Nathanson NM, Wess J, Liberman MC. Muscarinic signaling in the cochlea: presynaptic and postsynaptic effects on efferent feedback and afferent excitability. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 6751-62. PMID 20463237 DOI: 10.1523/JNEUROSCI.5080-09.2010  0.64
2010 Poulin B, Butcher A, McWilliams P, Bourgognon JM, Pawlak R, Kong KC, Bottrill A, Mistry S, Wess J, Rosethorne EM, Charlton SJ, Tobin AB. The M3-muscarinic receptor regulates learning and memory in a receptor phosphorylation/arrestin-dependent manner. Proceedings of the National Academy of Sciences of the United States of America. 107: 9440-5. PMID 20439723 DOI: 10.1073/pnas.0914801107  0.64
2010 De Azua IR, Scarselli M, Rosemond E, Gautam D, Jou W, Gavrilova O, Ebert PJ, Levitt P, Wess J. RGS4 is a negative regulator of insulin release from pancreatic β-cells in vitro and in vivo Proceedings of the National Academy of Sciences of the United States of America. 107: 7999-8004. PMID 20385802 DOI: 10.1073/pnas.1003655107  0.64
2010 Davis AA, Fritz JJ, Wess J, Lah JJ, Levey AI. Deletion of M1 muscarinic acetylcholine receptors increases amyloid pathology in vitro and in vivo. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 4190-6. PMID 20335454 DOI: 10.1523/JNEUROSCI.6393-09.2010  0.64
2010 Threlfell S, Clements MA, Khodai T, Pienaar IS, Exley R, Wess J, Cragg SJ. Striatal muscarinic receptors promote activity dependence of dopamine transmission via distinct receptor subtypes on cholinergic interneurons in ventral versus dorsal striatum. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 3398-408. PMID 20203199 DOI: 10.1523/JNEUROSCI.5620-09.2010  0.64
2010 Khurana S, Shah N, Cheng K, Shiu B, Samimi R, Belo A, Shant J, Drachenberg C, Wess J, Raufman JP. Scopolamine treatment and muscarinic receptor subtype-3 gene ablation augment azoxymethane-induced murine liver injury. The Journal of Pharmacology and Experimental Therapeutics. 333: 639-49. PMID 20197374 DOI: 10.1124/jpet.109.165118  0.64
2010 Shi Y, Oury F, Yadav VK, Wess J, Liu XS, Guo XE, Murshed M, Karsenty G. Signaling through the M(3) muscarinic receptor favors bone mass accrual by decreasing sympathetic activity. Cell Metabolism. 11: 231-8. PMID 20197056 DOI: 10.1016/j.cmet.2010.01.005  0.64
2010 Jeon J, Dencker D, Wörtwein G, Woldbye DP, Cui Y, Davis AA, Levey AI, Schütz G, Sager TN, Mørk A, Li C, Deng CX, Fink-Jensen A, Wess J. A subpopulation of neuronal M4 muscarinic acetylcholine receptors plays a critical role in modulating dopamine-dependent behaviors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 2396-405. PMID 20147565 DOI: 10.1523/JNEUROSCI.3843-09.2010  0.64
2010 Balasubramanian R, Ruiz de Azua I, Wess J, Jacobson KA. Activation of distinct P2Y receptor subtypes stimulates insulin secretion in MIN6 mouse pancreatic beta cells. Biochemical Pharmacology. 79: 1317-26. PMID 20067775 DOI: 10.1016/j.bcp.2009.12.026  0.64
2010 Thomsen M, Wess J, Fulton BS, Fink-Jensen A, Caine SB. Modulation of prepulse inhibition through both M1 and M 4 muscarinic receptors in mice Psychopharmacology. 208: 401-416. PMID 20013114 DOI: 10.1007/s00213-009-1740-z  0.68
2010 Thomsen M, Conn PJ, Lindsley C, Wess J, Boon JY, Fulton BS, Fink-Jensen A, Caine SB. Attenuation of cocaine's reinforcing and discriminative stimulus effects via muscarinic M1 acetylcholine receptor stimulation Journal of Pharmacology and Experimental Therapeutics. 332: 959-969. PMID 19996296 DOI: 10.1124/jpet.109.162057  0.68
2010 Schmidt LS, Miller AD, Lester DB, Bay-Richter C, Schülein C, Frikke-Schmidt H, Wess J, Blaha CD, Woldbye DP, Fink-Jensen A, Wortwein G. Increased amphetamine-induced locomotor activity, sensitization, and accumbal dopamine release in M5 muscarinic receptor knockout mice. Psychopharmacology. 207: 547-58. PMID 19820917 DOI: 10.1007/s00213-009-1685-2  0.64
2009 Tanahashi Y, Unno T, Matsuyama H, Ishii T, Yamada M, Wess J, Komori S. Multiple muscarinic pathways mediate the suppression of voltage-gated Ca2+ channels in mouse intestinal smooth muscle cells. British Journal of Pharmacology. 158: 1874-83. PMID 20050185 DOI: 10.1111/j.1476-5381.2009.00475.x  0.64
2009 Wright MC, Potluri S, Wang X, Dentcheva E, Gautam D, Tessler A, Wess J, Rich MM, Son YJ. Distinct muscarinic acetylcholine receptor subtypes contribute to stability and growth, but not compensatory plasticity, of neuromuscular synapses. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 14942-55. PMID 19940190 DOI: 10.1523/JNEUROSCI.2276-09.2009  0.64
2009 Guettier JM, Gautam D, Scarselli M, Ruiz de Azua I, Li JH, Rosemond E, Ma X, Gonzalez FJ, Armbruster BN, Lu H, Roth BL, Wess J. A chemical-genetic approach to study G protein regulation of beta cell function in vivo. Proceedings of the National Academy of Sciences of the United States of America. 106: 19197-202. PMID 19858481 DOI: 10.1073/pnas.0906593106  0.64
2009 Li JH, Gautam D, Han SJ, Guettier JM, Cui Y, Lu H, Deng C, O'Hare J, Jou W, Gavrilova O, Buettner C, Wess J. Hepatic muscarinic acetylcholine receptors are not critically involved in maintaining glucose homeostasis in mice Diabetes. 58: 2776-2787. PMID 19752163 DOI: 10.2337/db09-0522  0.64
2009 Li JH, Chou CL, Li B, Gavrilova O, Eisner C, Schnermann J, Anderson SA, Deng CX, Knepper MA, Wess J. A selective EP4 PGE2 receptor agonist alleviates disease in a new mouse model of X-linked nephrogenic diabetes insipidus. The Journal of Clinical Investigation. 119: 3115-26. PMID 19729836 DOI: 10.1172/JCI39680  0.64
2009 Cyphert JM, Kovarova M, Allen IC, Hartney JM, Murphy DL, Wess J, Koller BH. Cooperation between mast cells and neurons is essential for antigen-mediated bronchoconstriction. Journal of Immunology (Baltimore, Md. : 1950). 182: 7430-9. PMID 19494266 DOI: 10.4049/jimmunol.0900039  0.64
2009 Kitazawa T, Asakawa K, Nakamura T, Teraoka H, Unno T, Komori S, Yamada M, Wess J. M3 muscarinic receptors mediate positive inotropic responses in mouse atria: a study with muscarinic receptor knockout mice. The Journal of Pharmacology and Experimental Therapeutics. 330: 487-93. PMID 19429792 DOI: 10.1124/jpet.109.153304  0.64
2009 Gautam D, Jeon J, Starost MF, Han SJ, Hamdan FF, Cui Y, Parlow AF, Gavrilova O, Szalayova I, Mezey E, Wess J. Neuronal M3 muscarinic acetylcholine receptors are essential for somatotroph proliferation and normal somatic growth. Proceedings of the National Academy of Sciences of the United States of America. 106: 6398-403. PMID 19332789 DOI: 10.1073/pnas.0900977106  0.64
2008 Wess J, Han SJ, Kim SK, Jacobson KA, Li JH. Conformational changes involved in G-protein-coupled-receptor activation. Trends in Pharmacological Sciences. 29: 616-25. PMID 18838178 DOI: 10.1016/j.tips.2008.08.006  0.64
2007 Thomsen M, Wörtwein G, Fink-Jensen A, Woldbye DP, Wess J, Caine SB. Decreased prepulse inhibition and increased sensitivity to muscarinic, but not dopaminergic drugs in M5 muscarinic acetylcholine receptor knockout mice. Psychopharmacology. 192: 97-110. PMID 17310388 DOI: 10.1007/s00213-006-0682-y  0.68
2005 Thomsen M, Woldbye DP, Wörtwein G, Fink-Jensen A, Wess J, Caine SB. Reduced cocaine self-administration in muscarinic M5 acetylcholine receptor-deficient mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 8141-9. PMID 16148222 DOI: 10.1523/JNEUROSCI.2077-05.2005  0.68
2003 Fink-Jensen A, Fedorova I, Wörtwein G, Woldbye DP, Rasmussen T, Thomsen M, Bolwig TG, Knitowski KM, McKinzie DL, Yamada M, Wess J, Basile A. Role for M5 muscarinic acetylcholine receptors in cocaine addiction. Journal of Neuroscience Research. 74: 91-6. PMID 13130510 DOI: 10.1002/jnr.10728  0.64
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