| Year |
Citation |
Score |
| 2024 |
Her TK, Li J, Lin H, Liu D, Root KM, Regal JF, Alejandro EU, Cao R. Circadian Disruption across Lifespan Impairs Glucose Homeostasis and Insulin Sensitivity in Adult Mice. Metabolites. 14. PMID 38393018 DOI: 10.3390/metabo14020126 |
0.403 |
|
| 2023 |
Jo S, Beetch M, Gustafson E, Wong A, Oribamise E, Chung G, Vadrevu S, Satin LS, Bernal-Mizrachi E, Alejandro EU. Sex Differences in Pancreatic β-Cell Physiology and Glucose Homeostasis in C57BL/6J Mice. Journal of the Endocrine Society. 7: bvad099. PMID 37873500 DOI: 10.1210/jendso/bvad099 |
0.458 |
|
| 2023 |
Beetch M, Akhaphong B, Wong A, Clifton B, Jo S, Mohan R, Abrahante Llorens JE, Alejandro EU. Impact of placental mTOR deficiency on peripheral insulin signaling in adult mice offspring. Journal of Molecular Endocrinology. 71. PMID 37855320 DOI: 10.1530/JME-23-0035 |
0.403 |
|
| 2023 |
Wong A, Pritchard S, Moore M, Akhaphong B, Avula N, Beetch M, Fujitani Y, Alejandro EU. Overexpression of Pdx1, reduction of p53, or deletion of CHOP attenuates pancreas hypoplasia in mice with pancreas-specific O-GlcNAc Transferase deletion. The Journal of Biological Chemistry. 102878. PMID 36623733 DOI: 10.1016/j.jbc.2023.102878 |
0.407 |
|
| 2022 |
Wong A, Akhaphong B, Baumann D, Alejandro EU. Genetic Ablation of the Nutrient Sensor Ogt in Endocrine Progenitors Is Dispensable for β-Cell Development but Essential for Maintenance of β-Cell Mass. Biomedicines. 11. PMID 36672613 DOI: 10.3390/biomedicines11010105 |
0.46 |
|
| 2022 |
Jo S, Pritchard S, Wong A, Avula N, Essawy A, Hanover J, Alejandro EU. Pancreatic β-cell hyper-O-GlcNAcylation leads to impaired glucose homeostasis in vivo. Frontiers in Endocrinology. 13: 1040014. PMID 36387851 DOI: 10.3389/fendo.2022.1040014 |
0.553 |
|
| 2022 |
Root KM, Akhaphong B, Cedars MA, Molin AM, Huchthausen ME, Laule CF, Regal RR, Alejandro EU, Regal JF. Critical Role for Macrophages in the Developmental Programming of Pancreatic β-cell Area in Offspring of Gestational Hypertension. Diabetes. PMID 36125850 DOI: 10.2337/db22-0404 |
0.326 |
|
| 2022 |
Chung G, Mohan R, Beetch M, Jo S, Alejandro EU. Placental Insulin Receptor Transiently Regulates Glucose Homeostasis in the Adult Mouse Offspring of Multiparous Dams. Biomedicines. 10. PMID 35327377 DOI: 10.3390/biomedicines10030575 |
0.491 |
|
| 2022 |
Akhaphong B, Gregg B, Kumusoglu D, Jo S, Singer K, Scheys J, DelProposto J, Lumeng C, Bernal-Mizrachi E, Alejandro EU. Maternal High-Fat Diet During Pre-Conception and Gestation Predisposes Adult Female Offspring to Metabolic Dysfunction in Mice. Frontiers in Endocrinology. 12: 780300. PMID 35111136 DOI: 10.3389/fendo.2021.780300 |
0.374 |
|
| 2021 |
Mohan R, Jo S, Da Sol Chung E, Oribamise E, Lockridge A, Abrahante-Lloréns JE, Ruan HB, Yang XY, Alejandro EU. Pancreatic β-Cell O-GlcNAc Transferase Overexpression Increases Susceptibility to Metabolic Stressors in Female Mice. Cells. 10. PMID 34685781 DOI: 10.3390/cells10102801 |
0.801 |
|
| 2021 |
Mohan R, Jo S, Lockridge A, Ferrington DA, Murray K, Eschenlauer A, Bernal-Mizrachi E, Fujitani Y, Alejandro EU. OGT Regulates Mitochondrial Biogenesis and Function via Diabetes Susceptibility Gene Pdx1. Diabetes. PMID 34462257 DOI: 10.2337/db21-0468 |
0.757 |
|
| 2021 |
Moore M, Avula N, Jo S, Beetch M, Alejandro EU. Disruption of O-Linked N-Acetylglucosamine Signaling in Placenta Induces Insulin Sensitivity in Female Offspring. International Journal of Molecular Sciences. 22. PMID 34203166 DOI: 10.3390/ijms22136918 |
0.429 |
|
| 2021 |
Akhaphong B, Baumann DC, Beetch M, Lockridge AD, Jo S, Wong A, Zemanovic T, Mohan R, Fondevilla DL, Sia M, Pineda-Cortel MR, Alejandro EU. Placental mTOR-Complex1 regulates fetal programming of obesity and insulin resistance in mice. Jci Insight. PMID 34032632 DOI: 10.1172/jci.insight.149271 |
0.744 |
|
| 2021 |
Essawy A, Jo S, Beetch M, Lockridge A, Gustafson E, Alejandro EU. O-linked N-Acetylglucosamine Transferase (OGT) regulates pancreatic α-cell function in mice. The Journal of Biological Chemistry. 100297. PMID 33460647 DOI: 10.1016/j.jbc.2021.100297 |
0.76 |
|
| 2021 |
Lockridge A, Gustafson E, Wong A, Miller RF, Alejandro EU. Acute D-Serine Co-Agonism of β-Cell NMDA Receptors Potentiates Glucose-Stimulated Insulin Secretion and Excitatory β-Cell Membrane Activity. Cells. 10. PMID 33430405 DOI: 10.3390/cells10010093 |
0.778 |
|
| 2020 |
Esch N, Jo S, Moore M, Alejandro EU. Nutrient Sensor mTOR and OGT: Orchestrators of Organelle Homeostasis in Pancreatic -Cells. Journal of Diabetes Research. 2020: 8872639. PMID 33457426 DOI: 10.1155/2020/8872639 |
0.333 |
|
| 2020 |
Jo S, Lockridge A, Mohan R, Esch N, Schlichting R, Panigrahy N, Essawy A, Gustafson E, Alejandro EU. Translational Factor eIF4G1 Regulates Glucose Homeostasis and Pancreatic β-Cell Function. Diabetes. PMID 33115825 DOI: 10.2337/db20-0057 |
0.819 |
|
| 2020 |
Jo S, Lockridge A, Mohan R, Esch N, Schlichting R, Panigrahy N, Essawy A, Gustafson E, Alejandro EU. Translational Factor eIF4G1 Regulates Glucose Homeostasis and Pancreatic β-Cell Function. Diabetes. PMID 33109604 DOI: 10.2337/db200057 |
0.819 |
|
| 2020 |
Alejandro EU, Jo S, Akhaphong B, Llacer PR, Gianchandani M, Gregg B, Parlee SD, MacDougald OA, Bernal-Mizrachi E. Maternal low-protein diet on the last week of pregnancy contributes to insulin resistance and β-cell dysfunction in the mouse offspring. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. PMID 32877242 DOI: 10.1152/Ajpregu.00284.2019 |
0.458 |
|
| 2020 |
Lockridge A, Jo S, Gustafson E, Damberg N, Mohan R, Olson M, Abrahante JE, Alejandro EU. Islet O-GlcNAcylation Is Required for Lipid Potentiation of Insulin Secretion through SERCA2. Cell Reports. 31: 107609. PMID 32375037 DOI: 10.1016/j.celrep.2020.107609 |
0.793 |
|
| 2020 |
Baumann D, Wong A, Akhaphong B, Jo S, Pritchard S, Mohan R, Chung G, Zhang Y, Alejandro EU. Role of nutrient-driven O-GlcNAc-posttranslational modification in pancreatic exocrine and endocrine islet development. Development (Cambridge, England). PMID 32165492 DOI: 10.1242/dev.186643 |
0.317 |
|
| 2020 |
Regal JF, Root KM, Towner KJ, Akhaphong BU, Alejandro EU. Abstract 2: Increased Complement Regulator CD55 Is Associated With A Reduction In Pancreatic Beta Cell Area In Islets Of Rat Offspring Following Chronic Placental Ischemia-induced Hypertension Hypertension. 76. DOI: 10.1161/hyp.76.suppl_1.2 |
0.319 |
|
| 2020 |
Regal JF, Root KM, Towner KJ, Akhaphong B, Mohan R, Alejandro EU. Reduction in Pancreatic β Cell Area is Associated with Increased Islet Macrophage Message in Female Rat Offspring following Chronic Placental Ischemia The Faseb Journal. 34: 1-1. DOI: 10.1096/fasebj.2020.34.s1.02160 |
0.303 |
|
| 2019 |
Jo S, Lockridge A, Alejandro EU. eIF4G1 and carboxypeptidase E axis dysregulation in O-GlcNAc transferase-deficient pancreatic β cells contributes to hyperproinsulinemia in mice. The Journal of Biological Chemistry. PMID 31300553 DOI: 10.1074/Jbc.Ra119.008670 |
0.794 |
|
| 2019 |
Alejandro E, Baumann D, Wong A, Lockridge A, Mohan R, Alejandro E. Placental mTOR insufficiency during pregnancy predisposes female offspring to obesity-induced insulin resistance Placenta. 83: e12. DOI: 10.1016/J.Placenta.2019.06.045 |
0.725 |
|
| 2018 |
Akhaphong B, Lockridge A, Jo S, Mohan R, Wilcox JA, Wing CR, Regal JF, Alejandro EU. Reduced Uterine Perfusion Pressure Causes Loss of Pancreatic Beta Cell Area but Normal Function in Fetal Rat Offspring. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. PMID 30303709 DOI: 10.1152/Ajpregu.00458.2017 |
0.751 |
|
| 2018 |
Mohan R, Baumann DC, Alejandro EU. Fetal undernutrition, placental insufficiency and pancreatic β-cell development programming in utero. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. PMID 30110175 DOI: 10.1152/ajpregu.00072.2018 |
0.401 |
|
| 2018 |
Gregg BE, Botezatu N, Brill JD, Hafner H, Vadrevu S, Satin LS, Alejandro EU, Bernal-Mizrachi E. Gestational exposure to metformin programs improved glucose tolerance and insulin secretion in adult male mouse offspring. Scientific Reports. 8: 5745. PMID 29636523 DOI: 10.1038/s41598-018-23965-4 |
0.476 |
|
| 2018 |
MOHAN R, RUAN H, YANG X, ALEJANDRO E. Pancreatic Beta Cell O-GlcNAc Transferase Overexpression Increases Susceptibility to Streptozotocin- and High-Fat Diet–Induced Diabetes in Female Mice Diabetes. 67: 83-OR. DOI: 10.2337/Db18-83-Or |
0.573 |
|
| 2018 |
JO S, LOCKRIDGE AD, ALEJANDRO E. Hyperproinsulinemia in OGlcNAc Transferase Deficient Mice Is Associated with Loss of CPE and eIF4G1, but ß-Cell Deletion of eIF4G1 Induces Glucose Intolerance Independent of CPE Dysregulation Diabetes. 67: 2167-P. DOI: 10.2337/Db18-2167-P |
0.808 |
|
| 2018 |
LOCKRIDGE AD, JO S, DAMBERG NE, MOHAN R, ALEJANDRO E. Newly Revealed Role for OGT in Obesity-Precipitated ß-Cell Hyperinsulinemia Diabetes. 67: 2161-P. DOI: 10.2337/Db18-2161-P |
0.781 |
|
| 2018 |
ALEJANDRO E, BAUMANN D, JO S, AKHAPHONG B, LOCKRIDGE AD, MOHAN R. Deletion of OGlcNAc Transferase in Pancreatic Progenitors Causes Partial Pancreas Agenesis and Diabetes Independent of p53 in Mice Diabetes. 67: 195-OR. DOI: 10.2337/Db18-195-Or |
0.713 |
|
| 2017 |
Elghazi L, Blandino-Rosano M, Alejandro E, Cras-Méneur C, Bernal-Mizrachi E. Role of nutrients and mTOR signaling in the regulation of pancreatic progenitors development. Molecular Metabolism. 6: 560-573. PMID 28580286 DOI: 10.1016/J.Molmet.2017.03.010 |
0.506 |
|
| 2017 |
Alejandro EU, Bozadjieva N, Blandino-Rosano M, Wasan MA, Elghazi L, Vadrevu S, Satin L, Bernal-Mizrachi E. Overexpression of kinase-Dead mTOR Impairs Glucose Homeostasis by Regulating Insulin Secretion and Not β-Cell Mass. Diabetes. PMID 28546423 DOI: 10.2337/Db16-1349 |
0.539 |
|
| 2016 |
Lockridge AD, Baumann DC, Akhaphong B, Abrenica A, Miller RF, Alejandro EU. Serine racemase is expressed in islets and contributes to the regulation of glucose homeostasis. Islets. 0. PMID 27880078 DOI: 10.1080/19382014.2016.1260797 |
0.794 |
|
| 2015 |
Alejandro EU, Bozadjieva N, Kumusoglu D, Abdulhamid S, Levine H, Haataja L, Vadrevu S, Satin LS, Arvan P, Bernal-Mizrachi E. Disruption of O-linked N-Acetylglucosamine Signaling Induces ER Stress and β Cell Failure. Cell Reports. PMID 26673325 DOI: 10.1016/j.celrep.2015.11.020 |
0.436 |
|
| 2015 |
Alejandro EU, Gregg B, Blandino-Rosano M, Cras-Méneur C, Bernal-Mizrachi E. Natural history of β-cell adaptation and failure in type 2 diabetes. Molecular Aspects of Medicine. 42: 19-41. PMID 25542976 DOI: 10.1016/j.mam.2014.12.002 |
0.398 |
|
| 2014 |
Chan MT, Lim GE, Skovsø S, Yang YH, Albrecht T, Alejandro EU, Hoesli CA, Piret JM, Warnock GL, Johnson JD. Effects of insulin on human pancreatic cancer progression modeled in vitro. Bmc Cancer. 14: 814. PMID 25373319 DOI: 10.1186/1471-2407-14-814 |
0.717 |
|
| 2014 |
Gregg B, Elghazi L, Alejandro EU, Smith MR, Blandino-Rosano M, El-Gabri D, Cras-Méneur C, Bernal-Mizrachi E. Exposure of mouse embryonic pancreas to metformin enhances the number of pancreatic progenitors. Diabetologia. 57: 2566-75. PMID 25249235 DOI: 10.1007/s00125-014-3379-5 |
0.304 |
|
| 2014 |
Alejandro EU, Gregg B, Wallen T, Kumusoglu D, Meister D, Chen A, Merrins MJ, Satin LS, Liu M, Arvan P, Bernal-Mizrachi E. Maternal diet-induced microRNAs and mTOR underlie β cell dysfunction in offspring. The Journal of Clinical Investigation. 124: 4395-410. PMID 25180600 DOI: 10.1172/JCI74237 |
0.533 |
|
| 2012 |
Blandino-Rosano M, Chen AY, Scheys JO, Alejandro EU, Gould AP, Taranukha T, Elghazi L, Cras-Méneur C, Bernal-Mizrachi E. mTORC1 signaling and regulation of pancreatic β-cell mass. Cell Cycle (Georgetown, Tex.). 11: 1892-902. PMID 22544327 DOI: 10.4161/Cc.20036 |
0.435 |
|
| 2012 |
Blandino-Rosano M, Alejandro EU, Sathyamurthy A, Scheys JO, Gregg B, Chen AY, Rachdi L, Weiss A, Barker DJ, Gould AP, Elghazi L, Bernal-Mizrachi E. Enhanced beta cell proliferation in mice overexpressing a constitutively active form of Akt and one allele of p21Cip. Diabetologia. 55: 1380-9. PMID 22327314 DOI: 10.1007/S00125-012-2465-9 |
0.402 |
|
| 2011 |
Alejandro EU, Lim GE, Mehran AE, Hu X, Taghizadeh F, Pelipeychenko D, Baccarini M, Johnson JD. Pancreatic β-cell Raf-1 is required for glucose tolerance, insulin secretion, and insulin 2 transcription. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 25: 3884-95. PMID 21817126 DOI: 10.1096/Fj.10-180349 |
0.793 |
|
| 2010 |
Alejandro EU, Kalynyak TB, Taghizadeh F, Gwiazda KS, Rawstron EK, Jacob KJ, Johnson JD. Acute insulin signaling in pancreatic beta-cells is mediated by multiple Raf-1 dependent pathways. Endocrinology. 151: 502-12. PMID 20056832 DOI: 10.1210/En.2009-0678 |
0.623 |
|
| 2008 |
Jeffrey KD, Alejandro EU, Luciani DS, Kalynyak TB, Hu X, Li H, Lin Y, Townsend RR, Polonsky KS, Johnson JD. Carboxypeptidase E mediates palmitate-induced beta-cell ER stress and apoptosis. Proceedings of the National Academy of Sciences of the United States of America. 105: 8452-7. PMID 18550819 DOI: 10.1073/Pnas.0711232105 |
0.744 |
|
| 2008 |
Johnson JD, Alejandro EU. Control of pancreatic beta-cell fate by insulin signaling: The sweet spot hypothesis. Cell Cycle (Georgetown, Tex.). 7: 1343-7. PMID 18418065 DOI: 10.4161/Cc.7.10.5865 |
0.611 |
|
| 2008 |
Beith JL, Alejandro EU, Johnson JD. Insulin stimulates primary beta-cell proliferation via Raf-1 kinase. Endocrinology. 149: 2251-60. PMID 18202127 DOI: 10.1210/En.2007-1557 |
0.625 |
|
| 2008 |
Alejandro EU, Johnson JD. Inhibition of Raf-1 alters multiple downstream pathways to induce pancreatic beta-cell apoptosis. The Journal of Biological Chemistry. 283: 2407-17. PMID 18006502 DOI: 10.1074/Jbc.M703612200 |
0.5 |
|
| 2006 |
Johnson JD, Bernal-Mizrachi E, Alejandro EU, Han Z, Kalynyak TB, Li H, Beith JL, Gross J, Warnock GL, Townsend RR, Permutt MA, Polonsky KS. Insulin protects islets from apoptosis via Pdx1 and specific changes in the human islet proteome. Proceedings of the National Academy of Sciences of the United States of America. 103: 19575-80. PMID 17158802 DOI: 10.1073/Pnas.0604208103 |
0.728 |
|
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