Susan B Powell - Publications

University of California, San Diego, La Jolla, CA 
neurodevelopmental models, schizophrenia, autism, repetitive behavior, hallucinogens, sensorimotor gating

74 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Li J, Pinto-Duarte A, Zander M, Cuoco MS, Lai CY, Osteen J, Fang L, Luo C, Lucero JD, Gomez-Castanon R, Nery JR, Silva-Garcia I, Pang Y, Sejnowski TJ, Powell SB, et al. knockout in excitatory neurons impairs postnatal synapse maturation and increases the repressive histone modification H3K27me3. Elife. 11. PMID 35604009 DOI: 10.7554/eLife.66909  0.67
2022 Young JW, Barback CV, Stolz LA, Groman SM, Vera DR, Hoh C, Kotta KK, Minassian A, Powell SB, Brody AL. MicroPET evidence for a hypersensitive neuroinflammatory profile of gp120 mouse model of HIV. Psychiatry Research. Neuroimaging. 321: 111445. PMID 35101828 DOI: 10.1016/j.pscychresns.2022.111445  0.424
2021 Yue W, Caldwell S, Risbrough V, Powell S, Zhou X. Chronic presence of blood circulating anti-NMDAR1 autoantibodies impairs cognitive function in mice. Plos One. 16: e0256972. PMID 34473764 DOI: 10.1371/journal.pone.0256972  0.521
2021 Stout DM, Powell S, Kangavary A, Acheson DT, Nievergelt CM, Kash T, Simmons AN, Baker DG, Risbrough VB. Dissociable impact of childhood trauma and deployment trauma on affective modulation of startle. Neurobiology of Stress. 15: 100362. PMID 34258336 DOI: 10.1016/j.ynstr.2021.100362  0.625
2021 Sellgren CM, Imbeault S, Larsson MK, Oliveros A, Nilsson IAK, Codeluppi S, Orhan F, Bhat M, Tufvesson-Alm M, Gracias J, Kegel ME, Zheng Y, Faka A, Svedberg M, Powell SB, et al. GRK3 deficiency elicits brain immune activation and psychosis. Molecular Psychiatry. PMID 33976392 DOI: 10.1038/s41380-021-01106-0  0.309
2020 Friend SF, Nachnani R, Powell SB, Risbrough VB. C-Reactive Protein: Marker of risk for post-traumatic stress disorder and its potential for a mechanistic role in trauma response and recovery. The European Journal of Neuroscience. PMID 33131159 DOI: 10.1111/ejn.15031  0.489
2020 Amodeo DA, Hassan O, Klein L, Halberstadt AL, Powell SB. Acute serotonin 2A receptor activation impairs behavioral flexibility in mice. Behavioural Brain Research. 395: 112861. PMID 32814148 DOI: 10.1016/J.Bbr.2020.112861  0.781
2020 Behrens M, Lai C, Pinto-Duarte A, Li J, Luo C, Powell S, Ecker J, Mukamel E. Using the Power of Single-Nucleus Epigenomics to Map the Molecular Complexity of the Adult Brain Biological Psychiatry. 87: S61-S62. DOI: 10.1016/J.Biopsych.2020.02.179  0.673
2019 Ramachandran R, Wang Z, Saavedra C, Corr M, DiNardo A, Powell SB, Yaksh T. [EXPRESS] Role of Toll-like receptor 4 signaling in mast cell mediated trigeminal pain pathway. Molecular Pain. 1744806919867842. PMID 31342858 DOI: 10.1177/1744806919867842  0.338
2019 Amodeo DA, Lai CY, Hassan O, Mukamel EA, Behrens MM, Powell SB. Maternal immune activation impairs cognitive flexibility and alters transcription in frontal cortex. Neurobiology of Disease. PMID 30716470 DOI: 10.1016/J.Nbd.2019.01.025  0.73
2018 Halberstadt AL, van der Zee JVF, Chatha M, Geyer MA, Powell SB. Chronic treatment with a metabotropic mGlu2/3 receptor agonist diminishes behavioral response to a phenethylamine hallucinogen. Psychopharmacology. PMID 30448990 DOI: 10.1007/S00213-018-5118-Y  0.695
2017 Amitai N, Powell SB, Young JW. Phencyclidine increased while isolation rearing did not affect progressive ratio responding in rats: Investigating potential models of amotivation in schizophrenia. Behavioural Brain Research. PMID 29175446 DOI: 10.1016/J.Bbr.2017.11.026  0.563
2017 Khan A, Powell SB. Sensorimotor gating deficits in "two-hit" models of schizophrenia risk factors. Schizophrenia Research. PMID 29070440 DOI: 10.1016/J.Schres.2017.10.009  0.611
2017 Deslauriers J, Powell S, Risbrough VB. Immune signaling mechanisms of PTSD risk and symptom development: insights from animal models. Current Opinion in Behavioral Sciences. 14: 123-132. PMID 28758144 DOI: 10.1016/J.Cobeha.2017.01.005  0.538
2017 Deslauriers J, van Wijngaarde M, Geyer MA, Powell S, Risbrough VB. Effects of LPS-induced immune activation prior to trauma exposure on PTSD-like symptoms in mice. Behavioural Brain Research. PMID 28159589 DOI: 10.1016/J.Bbr.2017.01.048  0.624
2016 Khan A, de Jong LA, Kamenski ME, Higa KK, Lucero JD, Young JW, Margarita Behrens M, Powell SB. Adolescent GBR12909 exposure induces oxidative stress, disrupts parvalbumin-positive interneurons, and leads to hyperactivity and impulsivity in adult mice. Neuroscience. PMID 27890827 DOI: 10.1016/J.Neuroscience.2016.11.022  0.669
2016 Halberstadt AL, Hyun J, Ruderman MA, Powell SB. Effects of the psychotomimetic benzomorphan N-allylnormetazocine (SKF 10,047) on prepulse inhibition of startle in mice. Pharmacology, Biochemistry, and Behavior. PMID 27236030 DOI: 10.1016/J.Pbb.2016.05.009  0.653
2016 Halberstadt AL, Slepak N, Hyun J, Buell MR, Powell SB. The novel ketamine analog methoxetamine produces dissociative-like behavioral effects in rodents. Psychopharmacology. PMID 26758284 DOI: 10.1007/S00213-016-4203-3  0.648
2016 Powell SB, Swerdlow NR. Social Isolation Rearing and Sensorimotor Gating in Rat Models of Relevance to Schizophrenia: What We Know, and What We Do Not Know Handbook of Behavioral Neuroscience. 23: 125-138. DOI: 10.1016/B978-0-12-800981-9.00009-2  0.417
2015 Cope ZA, Powell SB, Young JW. Modeling neurodevelopmental cognitive deficits in tasks with cross-species translational validity. Genes, Brain, and Behavior. PMID 26667374 DOI: 10.1111/Gbb.12268  0.512
2015 Amitai N, Powell S, Weber M, Swerdlow NR, Young JW. Negative visuospatial priming in isolation-reared rats: Evidence of resistance to the disruptive effects of amphetamine. Cognitive, Affective & Behavioral Neuroscience. PMID 26220402 DOI: 10.3758/S13415-015-0369-0  0.5
2015 Higa KK, Ji B, Buell MR, Risbrough VB, Powell SB, Young JW, Geyer MA, Zhou X. Restoration of Sp4 in Forebrain GABAergic Neurons Rescues Hypersensitivity to Ketamine in Sp4 Hypomorphic Mice. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). PMID 26037489 DOI: 10.1093/Ijnp/Pyv063  0.715
2015 Powell SB, Khan A, Young JW, Scott CN, Buell MR, Caldwell S, Tsan E, de Jong LA, Acheson DT, Lucero J, Geyer MA, Behrens MM. Early Adolescent Emergence of Reversal Learning Impairments in Isolation-Reared Rats. Developmental Neuroscience. PMID 26022788 DOI: 10.1159/000430091  0.721
2015 McClatchy DB, Savas JN, Martínez-Bartolomé S, Park SK, Maher P, Powell SB, Yates JR. Global quantitative analysis of phosphorylation underlying phencyclidine signaling and sensorimotor gating in the prefrontal cortex. Molecular Psychiatry. PMID 25869802 DOI: 10.1038/Mp.2015.41  0.337
2015 Naviaux JC, Wang L, Li K, Bright AT, Alaynick WA, Williams KR, Powell SB, Naviaux RK. Antipurinergic therapy corrects the autism-like features in the Fragile X (Fmr1 knockout) mouse model. Molecular Autism. 6: 1. PMID 25705365 DOI: 10.1186/2040-2392-6-1  0.325
2014 Naviaux JC, Schuchbauer MA, Li K, Wang L, Risbrough VB, Powell SB, Naviaux RK. Reversal of autism-like behaviors and metabolism in adult mice with single-dose antipurinergic therapy. Translational Psychiatry. 4: e400. PMID 24937094 DOI: 10.1038/Tp.2014.33  0.586
2014 Liu XC, Holtze M, Powell SB, Terrando N, Larsson MK, Persson A, Olsson SK, Orhan F, Kegel M, Asp L, Goiny M, Schwieler L, Engberg G, Karlsson H, Erhardt S. Behavioral disturbances in adult mice following neonatal virus infection or kynurenine treatment--role of brain kynurenic acid. Brain, Behavior, and Immunity. 36: 80-9. PMID 24140727 DOI: 10.1016/J.Bbi.2013.10.010  0.393
2014 Amitai N, Young JW, Higa K, Sharp RF, Geyer MA, Powell SB. Isolation rearing effects on probabilistic learning and cognitive flexibility in rats. Cognitive, Affective & Behavioral Neuroscience. 14: 388-406. PMID 23943516 DOI: 10.3758/S13415-013-0204-4  0.623
2013 Swerdlow NR, Light GA, Trim RS, Breier MR, Hines SR, Powell SB. Forebrain gene expression predicts deficits in sensorimotor gating after isolation rearing in male rats. Behavioural Brain Research. 257: 118-28. PMID 24076151 DOI: 10.1016/J.Bbr.2013.09.005  0.317
2013 Swerdlow NR, Powell SB, Breier MR, Hines SR, Light GA. Coupling of gene expression in medial prefrontal cortex and nucleus accumbens after neonatal ventral hippocampal lesions accompanies deficits in sensorimotor gating and auditory processing in rats. Neuropharmacology. 75: 38-46. PMID 23810830 DOI: 10.1016/J.Neuropharm.2013.06.003  0.335
2013 Halberstadt AL, Powell SB, Geyer MA. Role of the 5-HTâ‚‚A receptor in the locomotor hyperactivity produced by phenylalkylamine hallucinogens in mice. Neuropharmacology. 70: 218-27. PMID 23376711 DOI: 10.1016/J.Neuropharm.2013.01.014  0.713
2012 Swerdlow NR, Light GA, Breier MR, Shoemaker JM, Saint Marie RL, Neary AC, Geyer MA, Stevens KE, Powell SB. Sensory and sensorimotor gating deficits after neonatal ventral hippocampal lesions in rats. Developmental Neuroscience. 34: 240-9. PMID 22572564 DOI: 10.1159/000336841  0.493
2012 Powell SB, Weber M, Geyer MA. Genetic models of sensorimotor gating: relevance to neuropsychiatric disorders. Current Topics in Behavioral Neurosciences. 12: 251-318. PMID 22367921 DOI: 10.1007/7854_2011_195  0.504
2012 Young JW, Powell SB, Geyer MA. Mouse pharmacological models of cognitive disruption relevant to schizophrenia. Neuropharmacology. 62: 1381-90. PMID 21726569 DOI: 10.1016/J.Neuropharm.2011.06.013  0.621
2012 Powell SB, Sejnowski TJ, Behrens MM. Behavioral and neurochemical consequences of cortical oxidative stress on parvalbumin-interneuron maturation in rodent models of schizophrenia. Neuropharmacology. 62: 1322-31. PMID 21315745 DOI: 10.1016/J.Neuropharm.2011.01.049  0.399
2011 Young JW, Powell SB, Scott CN, Zhou X, Geyer MA. The effect of reduced dopamine D4 receptor expression in the 5-choice continuous performance task: Separating response inhibition from premature responding. Behavioural Brain Research. 222: 183-92. PMID 21458500 DOI: 10.1016/J.Bbr.2011.03.054  0.653
2011 Halberstadt AL, Lehmann-Masten VD, Geyer MA, Powell SB. Interactive effects of mGlu5 and 5-HT2A receptors on locomotor activity in mice. Psychopharmacology. 215: 81-92. PMID 21153406 DOI: 10.1007/S00213-010-2115-1  0.718
2011 Halberstadt AL, Koedood L, Powell SB, Geyer MA. Differential contributions of serotonin receptors to the behavioral effects of indoleamine hallucinogens in mice. Journal of Psychopharmacology (Oxford, England). 25: 1548-61. PMID 21148021 DOI: 10.1177/0269881110388326  0.693
2011 Powell S. Behavioral Phenotyping of Mutant Mouse Models of Neuropsychiatric Disease: What We've Learned from Studies of Sensorimotor Gating Deficits in Schizophrenia Neurotoxicology and Teratology. 33: 495. DOI: 10.1016/J.Ntt.2011.05.017  0.368
2010 Powell SB. Models of neurodevelopmental abnormalities in schizophrenia. Current Topics in Behavioral Neurosciences. 4: 435-81. PMID 21312409 DOI: 10.1007/7854_2010_57  0.373
2010 Young JW, Powell SB, Geyer MA, Jeste DV, Risbrough VB. The mouse attentional-set-shifting task: a method for assaying successful cognitive aging? Cognitive, Affective & Behavioral Neuroscience. 10: 243-51. PMID 20498348 DOI: 10.3758/Cabn.10.2.243  0.682
2010 Gresack J, Powell S, Geyer M, Poore MS, Coste S, Risbrough V. CRF2 null mutation increases sensitivity to isolation rearing effects on locomotor activity in mice. Neuropeptides. 44: 349-53. PMID 20466421 DOI: 10.1016/J.Npep.2010.04.005  0.668
2010 Gresack JE, Risbrough VB, Scott CN, Coste S, Stenzel-Poore M, Geyer MA, Powell SB. Isolation rearing-induced deficits in contextual fear learning do not require CRF(2) receptors. Behavioural Brain Research. 209: 80-4. PMID 20097235 DOI: 10.1016/J.Bbr.2010.01.018  0.666
2010 Asp L, Holtze M, Powell SB, Karlsson H, Erhardt S. Neonatal infection with neurotropic influenza A virus induces the kynurenine pathway in early life and disrupts sensorimotor gating in adult Tap1-/- mice. The International Journal of Neuropsychopharmacology. 13: 475-85. PMID 19607757 DOI: 10.1017/S1461145709990253  0.308
2009 Ruderman MA, Powell SB, Geyer MA. A Kappa Opioid Model of Atypical Altered Consciousness and Psychosis: U50488, DOI, AC90179 Effects on Prepulse Inhibition and Locomotion in Mice. Journal of Young Investigators. 19: 1-7. PMID 25346645  0.438
2009 Powell SB, Zhou X, Geyer MA. Prepulse inhibition and genetic mouse models of schizophrenia. Behavioural Brain Research. 204: 282-94. PMID 19397931 DOI: 10.1016/J.Bbr.2009.04.021  0.514
2009 Halberstadt AL, van der Heijden I, Ruderman MA, Risbrough VB, Gingrich JA, Geyer MA, Powell SB. 5-HT(2A) and 5-HT(2C) receptors exert opposing effects on locomotor activity in mice. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 34: 1958-67. PMID 19322172 DOI: 10.1038/Npp.2009.29  0.746
2009 Young JW, Powell SB, Risbrough V, Marston HM, Geyer MA. Using the MATRICS to guide development of a preclinical cognitive test battery for research in schizophrenia. Pharmacology & Therapeutics. 122: 150-202. PMID 19269307 DOI: 10.1016/J.Pharmthera.2009.02.004  0.69
2008 Powell SB, Young JW, Ong JC, Caron MG, Geyer MA. Atypical antipsychotics clozapine and quetiapine attenuate prepulse inhibition deficits in dopamine transporter knockout mice. Behavioural Pharmacology. 19: 562-5. PMID 18690110 DOI: 10.1097/Fbp.0B013E32830Dc110  0.65
2008 Doherty JM, Masten VL, Powell SB, Ralph RJ, Klamer D, Low MJ, Geyer MA. Contributions of dopamine D1, D2, and D3 receptor subtypes to the disruptive effects of cocaine on prepulse inhibition in mice. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 33: 2648-56. PMID 18075489 DOI: 10.1038/Sj.Npp.1301657  0.776
2007 Powell SB, Geyer MA. Overview of animal models of schizophrenia. Current Protocols in Neuroscience / Editorial Board, Jacqueline N. Crawley ... [Et Al.]. Unit 9.24. PMID 18428667 DOI: 10.1002/0471142301.Ns0924S39  0.515
2007 Harte MK, Powell SB, Swerdlow NR, Geyer MA, Reynolds GP. Deficits in parvalbumin and calbindin immunoreactive cells in the hippocampus of isolation reared rats. Journal of Neural Transmission (Vienna, Austria : 1996). 114: 893-8. PMID 17594127 DOI: 10.1007/S00702-007-0627-6  0.497
2006 Barr AM, Powell SB, Markou A, Geyer MA. Iloperidone reduces sensorimotor gating deficits in pharmacological models, but not a developmental model, of disrupted prepulse inhibition in rats. Neuropharmacology. 51: 457-65. PMID 16762376 DOI: 10.1016/J.Neuropharm.2006.04.004  0.545
2006 Vanover KE, Weiner DM, Makhay M, Veinbergs I, Gardell LR, Lameh J, Del Tredici AL, Piu F, Schiffer HH, Ott TR, Burstein ES, Uldam AK, Thygesen MB, Schlienger N, Andersson CM, ... ... Powell SB, et al. Pharmacological and behavioral profile of N-(4-fluorophenylmethyl)-N-(1-methylpiperidin-4-yl)-N'-(4-(2-methylpropyloxy)phenylmethyl) carbamide (2R,3R)-dihydroxybutanedioate (2:1) (ACP-103), a novel 5-hydroxytryptamine(2A) receptor inverse agonist. The Journal of Pharmacology and Experimental Therapeutics. 317: 910-8. PMID 16469866 DOI: 10.1124/Jpet.105.097006  0.514
2006 Varty GB, Powell SB, Lehmann-Masten V, Buell MR, Geyer MA. Isolation rearing of mice induces deficits in prepulse inhibition of the startle response. Behavioural Brain Research. 169: 162-7. PMID 16406103 DOI: 10.1016/J.Bbr.2005.11.025  0.711
2005 Powell SB, Palomo J, Carasso BS, Bakshi VP, Geyer MA. Yohimbine disrupts prepulse inhibition in rats via action at 5-HT1A receptors, not alpha2-adrenoceptors. Psychopharmacology. 180: 491-500. PMID 15719216 DOI: 10.1007/S00213-005-2193-7  0.697
2005 Erhardt S, Powell S, Nilsson L, Linderholm K, Swerdlow N, Geyer M. P.2.05. Rats reared in social isolation displaydisrupted ppi and elevated levels of kynurenic acid in the hippocampus European Neuropsychopharmacology. 15: S34-S35. DOI: 10.1016/S0924-977X(05)80145-2  0.336
2004 Harte MK, Powell SB, Reynolds LM, Swerdlow NR, Geyer MA, Reynolds GP. Reduced N-acetylaspartate in the temporal cortex of rats reared in isolation. Biological Psychiatry. 56: 296-9. PMID 15312819 DOI: 10.1016/J.Biopsych.2004.06.009  0.49
2004 Powell SB, Geyer MA, Gallagher D, Paulus MP. The balance between approach and avoidance behaviors in a novel object exploration paradigm in mice. Behavioural Brain Research. 152: 341-9. PMID 15196802 DOI: 10.1016/J.Bbr.2003.10.020  0.466
2004 Belmonte MK, Cook EH, Anderson GM, Rubenstein JL, Greenough WT, Beckel-Mitchener A, Courchesne E, Boulanger LM, Powell SB, Levitt PR, Perry EK, Jiang YH, DeLorey TM, Tierney E. Autism as a disorder of neural information processing: directions for research and targets for therapy. Molecular Psychiatry. 9: 646-63. PMID 15037868 DOI: 10.1038/Sj.Mp.4001499  0.31
2004 Powell SB, Lehmann-Masten VD, Paulus MP, Gainetdinov RR, Caron MG, Geyer MA. MDMA "ecstasy" alters hyperactive and perseverative behaviors in dopamine transporter knockout mice. Psychopharmacology. 173: 310-7. PMID 14747902 DOI: 10.1007/S00213-003-1765-7  0.519
2004 Harte M, Powell S, Reynolds L, Geyer M, Reynolds G. S.4.05 Reduced N-acetyl aspartate levels in the temporal cortex of rats reared in isolation European Neuropsychopharmacology. 14: S66-S67. DOI: 10.1016/S0924-977X(04)90083-1  0.329
2003 Powell SB, Geyer MA, Preece MA, Pitcher LK, Reynolds GP, Swerdlow NR. Dopamine depletion of the nucleus accumbens reverses isolation-induced deficits in prepulse inhibition in rats. Neuroscience. 119: 233-40. PMID 12763084 DOI: 10.1016/S0306-4522(03)00122-2  0.479
2003 Powell SB, Paulus MP, Hartman DS, Godel T, Geyer MA. RO-10-5824 is a selective dopamine D4 receptor agonist that increases novel object exploration in C57 mice. Neuropharmacology. 44: 473-81. PMID 12646284 DOI: 10.1016/S0028-3908(02)00412-4  0.551
2003 Powell SB, Risbrough VB, Geyer MA. Potential use of animal models to examine antipsychotic prophylaxis for schizophrenia Clinical Neuroscience Research. 3: 289-296. DOI: 10.1016/S1566-2772(03)00089-6  0.658
2003 Vanover K, Weiner D, Harvey S, Powell S, Geyer M, Andersson C, Tolf B, Hacksell U, Brann M, Davis R. ACP-103, A 5-HT2A receptor inverse agonist, a novel potential treatment for psychosis Schizophrenia Research. 60: 317. DOI: 10.1016/S0920-9964(03)80268-2  0.319
2002 Powell SB, Geyer MA. Developmental markers of psychiatric disorders as identified by sensorimotor gating. Neurotoxicity Research. 4: 489-502. PMID 12754162 DOI: 10.1080/10298420290030578  0.536
2002 Powell SB, Swerdlow NR, Pitcher LK, Geyer MA. Isolation rearing-induced deficits in prepulse inhibition and locomotor habituation are not potentiated by water deprivation. Physiology & Behavior. 77: 55-64. PMID 12213502 DOI: 10.1016/S0031-9384(02)00817-X  0.494
2002 Presti MF, Powell SB, Lewis MH. Dissociation between spontaneously emitted and apomorphine-induced stereotypy in Peromyscus maniculatus bairdii. Physiology & Behavior. 75: 347-53. PMID 11897261 DOI: 10.1016/S0031-9384(02)00641-8  0.571
2000 Powell SB, Newman HA, McDonald TA, Bugenhagen P, Lewis MH. Development of spontaneous stereotyped behavior in deer mice: effects of early and late exposure to a more complex environment. Developmental Psychobiology. 37: 100-8. PMID 10954835 DOI: 10.1002/1098-2302(200009)37:2<100::Aid-Dev5>3.0.Co;2-6  0.534
1999 Powell SB, Newman HA, Pendergast JF, Lewis MH. A rodent model of spontaneous stereotypy: initial characterization of developmental, environmental, and neurobiological factors. Physiology & Behavior. 66: 355-63. PMID 10336165 DOI: 10.1016/S0031-9384(98)00303-5  0.561
1996 Powell SB, Bodfish JW, Parker DE, Crawford TW, Golden RN, Lewis MH. Growth differences associated with compulsive and stereotyped behavior disorders in adults with mental retardation. Anxiety. 2: 90-4. PMID 9160607 DOI: 10.1002/(Sici)1522-7154(1996)2:2<90::Aid-Anxi5>3.0.Co;2-H  0.496
1994 Lewis M, Bodfish J, Powell S, Golden R. Compulsive and stereotyped behavior disorders in mentally retarded patients Biological Psychiatry. 35: 643-644. DOI: 10.1016/0006-3223(94)90762-5  0.486
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