Stuart M. Brierley - Publications

Affiliations: 
SAMHRI Flinders University, Bedford Park, South Australia, Australia 

35/67 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Castro J, Harrington AM, Lieu T, Garcia-Caraballo S, Maddern J, Schober G, O'Donnell T, Grundy L, Lumsden AL, Miller PE, Ghetti A, Steinhoff MS, Poole DP, Dong X, Chang L, ... ... Brierley SM, et al. Activation of pruritogenic TGR5, MRGPRA3, and MRGPRC11 on colon-innervating afferents induces visceral hypersensitivity. Jci Insight. PMID 31536477 DOI: 10.1172/jci.insight.131712  0.44
2019 Israel MR, Tanaka BS, Castro J, Thongyoo P, Robinson SD, Zhao P, Deuis JR, Craik DJ, Durek T, Brierley SM, Waxman SG, Dib-Hajj SD, Vetter I. Na 1.6 regulates excitability of mechanosensitive sensory neurons. The Journal of Physiology. PMID 31087362 DOI: 10.1113/JP278148  0.44
2018 Grundy L, Harrington AM, Castro J, Garcia-Caraballo S, Deiteren A, Maddern J, Rychkov GY, Ge P, Peters S, Feil R, Miller P, Ghetti A, Hannig G, Kurtz CB, Silos-Santiago I, ... Brierley SM, et al. Chronic linaclotide treatment reduces colitis-induced neuroplasticity and reverses persistent bladder dysfunction. Jci Insight. 3. PMID 30282832 DOI: 10.1172/jci.insight.121841  0.44
2018 Salvatierra J, Castro J, Erickson A, Li Q, Braz J, Gilchrist J, Grundy L, Rychkov GY, Deiteren A, Rais R, King GF, Slusher BS, Basbaum A, Pasricha PJ, Brierley SM, et al. NaV1.1 inhibition can reduce visceral hypersensitivity. Jci Insight. 3. PMID 29875317 DOI: 10.1172/jci.insight.121000  0.44
2018 Sadeghi M, Carstens BB, Callaghan BP, Daniel JT, Tae HS, O'Donnell T, Castro J, Brierley SM, Adams DJ, Craik DJ, Clark RJ. Structure-activity studies reveal the molecular basis for GABAB-receptor mediated inhibition of high voltage-activated calcium channels by α-conotoxin Vc1.1. Acs Chemical Biology. PMID 29746088 DOI: 10.1021/acschembio.8b00190  0.44
2018 Sadeghi M, Erickson A, Castro J, Deiteren A, Harrington AM, Grundy L, Adams DJ, Brierley SM. Contribution of membrane receptor signalling to chronic visceral pain. The International Journal of Biochemistry & Cell Biology. PMID 29477359 DOI: 10.1016/j.biocel.2018.02.017  0.44
2018 Erickson A, Deiteren A, Harrington AM, Garcia-Caraballo S, Castro J, Caldwell A, Grundy L, Brierley SM. Voltage-gated sodium channels: (NaV )igating the field to determine their contribution to visceral nociception. The Journal of Physiology. PMID 29318638 DOI: 10.1113/JP273461  0.44
2017 Castro J, Grundy L, Deiteren A, Harrington AM, O'Donnell T, Maddern J, Moore J, Garcia-Caraballo S, Rychkov GY, Yu R, Kaas Q, Craik DJ, Adams DJ, Brierley SM. Cyclic analogues of α-conotoxin Vc1.1 inhibit colonic nociceptors and provide analgesia in a mouse model of chronic abdominal pain. British Journal of Pharmacology. PMID 29194563 DOI: 10.1111/bph.14115  0.44
2016 Carstens BB, Berecki G, Daniel JT, Lee HS, Jackson KA, Tae HS, Sadeghi M, Castro J, O'Donnell T, Deiteren A, Brierley SM, Craik DJ, Adams DJ, Clark RJ. Structure-Activity Studies of Cysteine-Rich α-Conotoxins that Inhibit High Voltage-Activated Calcium Channels via GABAB Receptor Activation Reveal a Minimal Functional Motif. Angewandte Chemie (International Ed. in English). PMID 26948522 DOI: 10.1002/anie.201600297  0.44
2016 Castro J, Harrington AM, Garcia-Caraballo S, Maddern J, Grundy L, Zhang J, Page G, Miller PE, Craik DJ, Adams DJ, Brierley SM. α-Conotoxin Vc1.1 inhibits human dorsal root ganglion neuroexcitability and mouse colonic nociception via GABAB receptors. Gut. PMID 26887818 DOI: 10.1136/gutjnl-2015-310971  0.44
2016 Brust A, Croker DE, Colless B, Ragnarsson L, Andersson A, Jain K, Caraballo SG, Castro J, Brierley SM, Alewood PF, Lewis RJ. Conopeptide-derived κ-opioid agonists (conorphins): potent, selective and metabolic stable dynorphinA mimetics with anti-nociceptive properties. Journal of Medicinal Chemistry. PMID 26859603 DOI: 10.1021/acs.jmedchem.5b00911  0.44
2014 Hughes PA, Moretta M, Lim A, Grasby DJ, Bird D, Brierley SM, Liebregts T, Adam B, Blackshaw LA, Holtmann G, Bampton P, Hoffmann P, Andrews JM, Zola H, Krumbiegel D. Immune derived opioidergic inhibition of viscerosensory afferents is decreased in Irritable Bowel Syndrome patients. Brain, Behavior, and Immunity. 42: 191-203. PMID 25063707 DOI: 10.1016/j.bbi.2014.07.001  0.44
2014 Malsch P, Andratsch M, Vogl C, Link AS, Alzheimer C, Brierley SM, Hughes PA, Kress M. Deletion of interleukin-6 signal transducer gp130 in small sensory neurons attenuates mechanonociception and down-regulates TRPA1 expression. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 9845-56. PMID 25057188 DOI: 10.1523/JNEUROSCI.5161-13.2014  0.44
2014 de Araujo AD, Mobli M, Castro J, Harrington AM, Vetter I, Dekan Z, Muttenthaler M, Wan J, Lewis RJ, King GF, Brierley SM, Alewood PF. Selenoether oxytocin analogues have analgesic properties in a mouse model of chronic abdominal pain. Nature Communications. 5: 3165. PMID 24476666 DOI: 10.1038/ncomms4165  0.44
2014 Hughes PA, Castro J, Harrington AM, Isaacs N, Moretta M, Hicks GA, Urso DM, Brierley SM. Increased κ-opioid receptor expression and function during chronic visceral hypersensitivity. Gut. 63: 1199-200. PMID 24285775 DOI: 10.1136/gutjnl-2013-306240  0.44
2013 Castro J, Harrington AM, Hughes PA, Martin CM, Ge P, Shea CM, Jin H, Jacobson S, Hannig G, Mann E, Cohen MB, MacDougall JE, Lavins BJ, Kurtz CB, Silos-Santiago I, ... ... Brierley SM, et al. Linaclotide inhibits colonic nociceptors and relieves abdominal pain via guanylate cyclase-C and extracellular cyclic guanosine 3',5'-monophosphate. Gastroenterology. 145: 1334-46.e1-11. PMID 23958540 DOI: 10.1053/j.gastro.2013.08.017  0.44
2013 Kentish SJ, O'Donnell TA, Isaacs NJ, Young RL, Li H, Harrington AM, Brierley SM, Wittert GA, Blackshaw LA, Page AJ. Gastric vagal afferent modulation by leptin is influenced by food intake status. The Journal of Physiology. 591: 1921-34. PMID 23266933 DOI: 10.1113/jphysiol.2012.247577  0.44
2013 Hughes PA, Harrington AM, Castro J, Liebregts T, Adam B, Grasby DJ, Isaacs NJ, Maldeniya L, Martin CM, Persson J, Andrews JM, Holtmann G, Blackshaw LA, Brierley SM. Sensory neuro-immune interactions differ between irritable bowel syndrome subtypes. Gut. 62: 1456-65. PMID 22767422 DOI: 10.1136/gutjnl-2011-301856  0.44
2012 Boakye PA, Brierley SM, Pasilis SP, Balemba OB. Garcinia buchananii bark extract is an effective anti-diarrheal remedy for lactose-induced diarrhea. Journal of Ethnopharmacology. 142: 539-47. PMID 22643232 DOI: 10.1016/j.jep.2012.05.034  0.44
2012 Harrington AM, Brierley SM, Isaacs N, Hughes PA, Castro J, Blackshaw LA. Sprouting of colonic afferent central terminals and increased spinal mitogen-activated protein kinase expression in a mouse model of chronic visceral hypersensitivity Journal of Comparative Neurology. 520: 2241-2255. PMID 22237807 DOI: 10.1002/cne.23042  0.44
2011 Blackshaw LA, Brierley SM, Hughes PA, Harrington AM. The hot mustard receptor's role in gut motor function Gastroenterology. 141: 423-427. PMID 21703264 DOI: 10.1053/j.gastro.2011.06.028  0.44
2011 Brierley SM, Castro J, Harrington AM, Hughes PA, Page AJ, Rychkov GY, Blackshaw LA. TRPA1 contributes to specific mechanically activated currents and sensory neuron mechanical hypersensitivity Journal of Physiology. 589: 3575-3593. PMID 21558163 DOI: 10.1113/jphysiol.2011.206789  0.44
2011 Harrington AM, Hughes PA, Martin CM, Yang J, Castro J, Isaacs NJ, Ashley Blackshaw L, Brierley SM. A novel role for TRPM8 in visceral afferent function Pain. 152: 1459-1468. PMID 21489690 DOI: 10.1016/j.pain.2011.01.027  0.44
2009 Brierley SM, Hughes PA, Page AJ, Kwan KY, Martin CM, O'Donnell TA, Cooper NJ, Harrington AM, Adam B, Liebregts T, Holtmann G, Corey DP, Rychkov GY, Blackshaw LA. The ion channel TRPA1 is required for normal mechanosensation and is modulated by algesic stimuli. Gastroenterology. 137: 2084-2095.e3. PMID 19632231 DOI: 10.1053/j.gastro.2009.07.048  0.44
2008 Brierley SM, Page AJ, Hughes PA, Adam B, Liebregts T, Cooper NJ, Holtmann G, Liedtke W, Blackshaw LA. Selective role for TRPV4 ion channels in visceral sensory pathways. Gastroenterology. 134: 2059-69. PMID 18343379 DOI: 10.1053/j.gastro.2008.01.074  0.44
2008 Sipe WE, Brierley SM, Martin CM, Phillis BD, Cruz FB, Grady EF, Liedtke W, Cohen DM, Vanner S, Blackshaw LA, Bunnett NW. Transient receptor potential vanilloid 4 mediates protease activated receptor 2-induced sensitization of colonic afferent nerves and visceral hyperalgesia. American Journal of Physiology. Gastrointestinal and Liver Physiology. 294: G1288-98. PMID 18325985 DOI: 10.1152/ajpgi.00002.2008  0.44
2008 Lindström E, Brusberg M, Hughes PA, Martin CM, Brierley SM, Phillis BD, Martinsson R, Abrahamsson C, Larsson H, Martinez V, Blackshaw LA. Involvement of metabotropic glutamate 5 receptor in visceral pain. Pain. 137: 295-305. PMID 17937975 DOI: 10.1016/j.pain.2007.09.008  0.44
2007 Page AJ, Slattery JA, Brierley SM, Jacoby AS, Blackshaw LA. Involvement of galanin receptors 1 and 2 in the modulation of mouse vagal afferent mechanosensitivity Journal of Physiology. 583: 675-684. PMID 17627995 DOI: 10.1113/jphysiol.2007.135939  0.44
2007 Page AJ, Brierley SM, Martin CM, Hughes PA, Blackshaw LA. Acid sensing ion channels 2 and 3 are required for inhibition of visceral nociceptors by benzamil Pain. 133: 150-160. PMID 17467171 DOI: 10.1016/j.pain.2007.03.019  0.44
2007 Page AJ, Slattery JA, Milte C, Laker R, O'Donnell T, Dorian C, Brierley SM, Blackshaw LA. Ghrelin selectively reduces mechanosensitivity of upper gastrointestinal vagal afferents American Journal of Physiology - Gastrointestinal and Liver Physiology. 292. PMID 17290011 DOI: 10.1152/ajpgi.00536.2006  0.44
2007 Hughes PA, Brierley SM, Young RL, Blackshaw LA. Localization and comparative analysis of acid-sensing ion channel (ASIC1, 2, and 3) mRNA expression in mouse colonic sensory neurons within thoracolumbar dorsal root ganglia. The Journal of Comparative Neurology. 500: 863-75. PMID 17177258 DOI: 10.1002/cne.21204  0.44
2006 Slattery JA, Page AJ, Dorian CL, Brierley SM, Blackshaw LA. Potentiation of mouse vagal afferent mechanosensitivity by ionotropic and metabotropic glutamate receptors Journal of Physiology. 577: 295-306. PMID 16945965 DOI: 10.1113/jphysiol.2006.117762  0.44
2005 Brierley SM, Carter R, Jones W, Xu L, Robinson DR, Hicks GA, Gebhart GF, Blackshaw LA. Differential chemosensory function and receptor expression of splanchnic and pelvic colonic afferents in mice. The Journal of Physiology. 567: 267-81. PMID 15946967 DOI: 10.1113/jphysiol.2005.089714  0.44
2004 Page AJ, Brierley SM, Martin CM, Martinez-Salgado C, Wemmie JA, Brennan TJ, Symonds E, Omari T, Lewin GR, Welsh MJ, Blackshaw LA. The ion channel ASIC1 contributes to visceral but not cutaneous mechanoreceptor function. Gastroenterology. 127: 1739-47. PMID 15578512 DOI: 10.1053/j.gastro.2004.08.061  0.44
2004 Brierley SM, Jones RC, Gebhart GF, Blackshaw LA. Splanchnic and pelvic mechanosensory afferents signal different qualities of colonic stimuli in mice. Gastroenterology. 127: 166-78. PMID 15236183 DOI: 10.1053/j.gastro.2004.04.008  0.44
Low-probability matches
2019 Ge P, Ren J, Harrington AM, Grundy L, Castro J, Brierley SM, Hannig G. Linaclotide treatment reduces endometriosis-associated vaginal hyperalgesia and mechanical allodynia through viscero-visceral cross-talk. Pain. PMID 31335750 DOI: 10.1097/j.pain.0000000000001657  0.24
2019 Harrington AM, Garcia Caraballo S, Maddern JE, Grundy L, Castro J, Brierley SM. Colonic afferent input and dorsal horn neuron activation differs between the thoracolumbar and lumbosacral spinal cord. American Journal of Physiology. Gastrointestinal and Liver Physiology. PMID 31188624 DOI: 10.1152/ajpgi.00013.2019  0.24
2018 Grundy L, Harrington AM, Caldwell A, Castro J, Staikopoulos V, Zagorodnyuk VP, Brookes SJH, Spencer NJ, Brierley SM. Translating peripheral bladder afferent mechanosensitivity to neuronal activation within the lumbosacral spinal cord of mice. Pain. PMID 30531372 DOI: 10.1097/j.pain.0000000000001453  0.24
2017 Inserra MC, Israel MR, Caldwell A, Castro J, Deuis JR, Harrington AM, Keramidas A, Garcia-Caraballo S, Maddern J, Erickson A, Grundy L, Rychkov GY, Zimmermann K, Lewis RJ, Brierley SM, et al. Multiple sodium channel isoforms mediate the pathological effects of Pacific ciguatoxin-1. Scientific Reports. 7: 42810. PMID 28225079 DOI: 10.1038/srep42810  0.24
2016 Osteen JD, Herzig V, Gilchrist J, Emrick JJ, Zhang C, Wang X, Castro J, Garcia-Caraballo S, Grundy L, Rychkov GY, Weyer AD, Dekan Z, Undheim EA, Alewood P, Stucky CL, ... Brierley SM, et al. Selective spider toxins reveal a role for the Nav1.1 channel in mechanical pain. Nature. PMID 27281198 DOI: 10.1038/nature17976  0.24
2018 Grundy L, Erickson A, Caldwell A, Garcia-Caraballo S, Rychkov G, Harrington A, Brierley SM. Tetrodotoxin-sensitive voltage-gated sodium channels regulate bladder afferent responses to distension. Pain. PMID 30157135 DOI: 10.1097/j.pain.0000000000001368  0.2
2017 Spencer NJ, Greenheigh S, Kyloh M, Hibberd TJ, Sharma H, Grundy L, Brierley SM, Harrington AM, Beckett EA, Brookes SJ, Zagorodnyuk VP. Identifying unique subtypes of spinal afferent nerve endings within the urinary bladder of mice. The Journal of Comparative Neurology. PMID 29178500 DOI: 10.1002/cne.24362  0.2
2010 Brierley SM, Hughes PA, Harrington AM, Rychkov GY, Blackshaw LA. Identifying the Ion Channels Responsible for Signaling Gastro-Intestinal Based Pain. Pharmaceuticals (Basel, Switzerland). 3: 2768-2798. PMID 27713376 DOI: 10.3390/ph3092768  0.2
2019 Braga Emidio N, Hoffmann W, Brierley SM, Muttenthaler M. Trefoil Factor Family: Unresolved Questions and Clinical Perspectives. Trends in Biochemical Sciences. PMID 30792027 DOI: 10.1016/j.tibs.2019.01.004  0.16
2018 Jimenez-Vargas NN, Pattison LA, Zhao P, Lieu T, Latorre R, Jensen DD, Castro J, Aurelio L, Le GT, Flynn B, Herenbrink CK, Yeatman HR, Edgington-Mitchell L, Porter CJH, Halls ML, ... ... Brierley SM, et al. Protease-activated receptor-2 in endosomes signals persistent pain of irritable bowel syndrome. Proceedings of the National Academy of Sciences of the United States of America. PMID 30012612 DOI: 10.1073/pnas.1721891115  0.12
2018 Guerrero-Alba R, Valdez-Morales EE, Jiménez-Vargas NN, Bron R, Poole D, Reed D, Castro J, Campaniello M, Hughes PA, Brierley SM, Bunnett N, Lomax AE, Vanner S. CO-EXPRESSION OF μ AND ∂ OPIOID RECEPTORS BY MOUSE COLONIC NOCICEPTORS. British Journal of Pharmacology. PMID 29579315 DOI: 10.1111/bph.14222  0.12
2017 Jami S, Erickson A, Brierley SM, Vetter I. Pain-Causing Venom Peptides: Insights into Sensory Neuron Pharmacology. Toxins. 10. PMID 29280959 DOI: 10.3390/toxins10010015  0.12
2017 Bellono NW, Bayrer JR, Leitch DB, Castro J, Zhang C, O'Donnell TA, Brierley SM, Ingraham HA, Julius D. Enterochromaffin Cells Are Gut Chemosensors that Couple to Sensory Neural Pathways. Cell. PMID 28648659 DOI: 10.1016/j.cell.2017.05.034  0.12
2016 Campaniello MA, Mavrangelos C, Eade S, Harrington AM, Ashley Blackshaw L, Brierley SM, Smid SD, Hughes PA. Acute colitis chronically alters immune infiltration mechanisms and sensory neuro-immune interactions. Brain, Behavior, and Immunity. PMID 27864046 DOI: 10.1016/j.bbi.2016.11.015  0.12
2015 Fournel A, Drougard A, Duparc T, Marlin A, Brierley SM, Castro J, Le-Gonidec S, Masri B, Colom A, Lucas A, Rousset P, Cenac N, Vergnolle N, Valet P, Cani PD, et al. Apelin targets gut contraction to control glucose metabolism via the brain. Gut. PMID 26565000 DOI: 10.1136/gutjnl-2015-310230  0.12
2019 Chess-Williams R, Sellers DJ, Brierley SM, Grundy D, Grundy L. Purinergic receptor mediated calcium signalling in urothelial cells. Scientific Reports. 9: 16101. PMID 31695098 DOI: 10.1038/s41598-019-52531-9  0.08
2019 Brierley SM, Goh KGK, Sullivan MJ, Moore KH, Ulett GC, Grundy L. Innate immune response to bacterial urinary tract infection sensitises high-threshold bladder afferents and recruits silent nociceptors. Pain. PMID 31479069 DOI: 10.1097/j.pain.0000000000001692  0.08
2018 Grundy L, Caldwell A, Brierley SM. Mechanisms Underlying Overactive Bladder and Interstitial Cystitis/Painful Bladder Syndrome. Frontiers in Neuroscience. 12: 931. PMID 30618560 DOI: 10.3389/fnins.2018.00931  0.08
2018 Grundy L, Erickson A, Brierley SM. Visceral Pain. Annual Review of Physiology. PMID 30379615 DOI: 10.1146/annurev-physiol-020518-114525  0.08
2018 Grundy L, Chess-Williams R, Brierley SM, Mills K, Moore KH, Mansfield K, Rose'Meyer R, Sellers DJ, Grundy D. NKA enhances bladder afferent mechanosensitivity via urothelial and detrusor activation. American Journal of Physiology. Renal Physiology. PMID 29897284 DOI: 10.1152/ajprenal.00106.2018  0.08
2018 Desormeaux C, Bautzova T, Garcia-Caraballo S, Rolland C, Barbaro MR, Brierley SM, Barbara G, Vergnolle N, Cenac N. Protease-Activated Receptor 1 is Implicated in Irritable Bowel Syndrome Mediators-Induced Signalling to Thoracic Human Sensory Neurons. Pain. PMID 29554016 DOI: 10.1097/j.pain.0000000000001208  0.08
2017 Grundy L, Brierley SM. Cross-organ sensitisation between the colon and bladder: To pee, or not to pee? American Journal of Physiology. Gastrointestinal and Liver Physiology. ajpgi.00272.2017. PMID 29146678 DOI: 10.1152/ajpgi.00272.2017  0.08
2017 Lee MC, McCubbin JA, Christensen AD, Poole DP, Rajasekhar P, Lieu T, Bunnett NW, Garcia-Caraballo S, Erickson A, Brierley SM, Saleh R, Achuthan A, Fleetwood AJ, Anderson RL, Hamilton JA, et al. G-CSF Receptor Blockade Ameliorates Arthritic Pain and Disease. Journal of Immunology (Baltimore, Md. : 1950). PMID 28320832 DOI: 10.4049/jimmunol.1602127  0.08
2013 Blackshaw LA, Brierley SM. Emerging receptor target in the pharmacotherapy of irritable bowel syndrome with constipation. Expert Review of Gastroenterology & Hepatology. 7: 15-9. PMID 23859756 DOI: 10.1586/17474124.2013.820045  0.04
2011 Liebregts T, Adam B, Bredack C, Gururatsakul M, Pilkington KR, Brierley SM, Blackshaw LA, Gerken G, Talley NJ, Holtmann G. Small bowel homing T cells are associated with symptoms and delayed gastric emptying in functional dyspepsia. The American Journal of Gastroenterology. 106: 1089-98. PMID 21245834 DOI: 10.1038/ajg.2010.512  0.04
2018 Brierley SM, Hibberd TJ, Spencer NJ. Spinal Afferent Innervation of the Colon and Rectum. Frontiers in Cellular Neuroscience. 12: 467. PMID 30564102 DOI: 10.3389/fncel.2018.00467  0.01
2014 Brierley SM, Linden DR. Neuroplasticity and dysfunction after gastrointestinal inflammation. Nature Reviews. Gastroenterology & Hepatology. 11: 611-27. PMID 25001973 DOI: 10.1038/nrgastro.2014.103  0.01
2012 Brierley SM. Guanylate cyclase-C receptor activation: unexpected biology. Current Opinion in Pharmacology. 12: 632-40. PMID 23131468 DOI: 10.1016/j.coph.2012.10.005  0.01
2011 Brierley SM, Kelber O. Use of natural products in gastrointestinal therapies. Current Opinion in Pharmacology. 11: 604-11. PMID 21996284 DOI: 10.1016/j.coph.2011.09.007  0.01
2010 Brierley SM. Visualising vagal afferent neurons and their terminals whilst silencing TRPV1. The Journal of Physiology. 588: 4069-70. PMID 21037315 DOI: 10.1113/jphysiol.2010.199711  0.01
2010 Brierley SM. All ahead stop! How intestinal motility adapts to cope with inflammation induced ulceration. The Journal of Physiology. 588: 753-4. PMID 20194135 DOI: 10.1113/jphysiol.2010.187898  0.01
2010 Brierley SM. Molecular basis of mechanosensitivity. Autonomic Neuroscience : Basic & Clinical. 153: 58-68. PMID 19683967 DOI: 10.1016/j.autneu.2009.07.017  0.01
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