| Year |
Citation |
Score |
| 2024 |
Borland G, Wilkie SE, Thomson J, Wang Z, Tullet JMA, Alic N, Selman C. Polr3b heterozygosity in mice induces both beneficial and deleterious effects on health during ageing with no effect on lifespan. Aging Cell. e14141. PMID 38465473 DOI: 10.1111/acel.14141 |
0.309 |
|
| 2024 |
Ureña E, Xu B, Regan JC, Atilano ML, Minkley LJ, Filer D, Lu YX, Bolukbasi E, Khericha M, Alic N, Partridge L. Trametinib ameliorates aging-associated gut pathology in females by reducing Pol III activity in intestinal stem cells. Proceedings of the National Academy of Sciences of the United States of America. 121: e2311313121. PMID 38241436 DOI: 10.1073/pnas.2311313121 |
0.76 |
|
| 2022 |
Javidnia S, Cranwell S, Mueller SH, Selman C, Tullet JMA, Kuchenbaecker K, Alic N. Mendelian randomization analyses implicate biogenesis of translation machinery in human aging. Genome Research. 32: 258-265. PMID 35078808 DOI: 10.1101/gr.275636.121 |
0.312 |
|
| 2020 |
Martínez Corrales G, Alic N. Evolutionary Conservation of Transcription Factors Affecting Longevity. Trends in Genetics : Tig. 36: 373-382. PMID 32294417 DOI: 10.1016/J.Tig.2020.02.003 |
0.481 |
|
| 2020 |
Woodling NS, Aleyakpo B, Dyson MC, Minkley LJ, Rajasingam A, Dobson AJ, Leung KHC, Pomposova S, Fuentealba M, Alic N, Partridge L. The neuronal receptor tyrosine kinase Alk is a target for longevity. Aging Cell. e13137. PMID 32291952 DOI: 10.1111/Acel.13137 |
0.607 |
|
| 2020 |
Bettedi L, Yan A, Schuster E, Alic N, Foukas LC. Increased mitochondrial and lipid metabolism is a conserved effect of Insulin/PI3K pathway downregulation in adipose tissue. Scientific Reports. 10: 3418. PMID 32099025 DOI: 10.1038/S41598-020-60210-3 |
0.491 |
|
| 2020 |
Martínez Corrales G, Filer D, Wenz KC, Rogan A, Phillips G, Li M, Feseha Y, Broughton SJ, Alic N. Partial Inhibition of RNA Polymerase I Promotes Animal Health and Longevity. Cell Reports. 30: 1661-1669.e4. PMID 32049000 DOI: 10.1016/J.Celrep.2020.01.017 |
0.427 |
|
| 2019 |
Dobson AJ, Boulton-McDonald R, Houchou L, Svermova T, Ren Z, Subrini J, Vazquez-Prada M, Hoti M, Rodriguez-Lopez M, Ibrahim R, Gregoriou A, Gkantiragas A, Bähler J, Ezcurra M, Alic N. Longevity is determined by ETS transcription factors in multiple tissues and diverse species. Plos Genetics. 15: e1008212. PMID 31356597 DOI: 10.1371/Journal.Pgen.1008212 |
0.461 |
|
| 2017 |
Filer D, Thompson MA, Takhaveev V, Dobson AJ, Kotronaki I, Green JWM, Heinemann M, Tullet JMA, Alic N. RNA polymerase III limits longevity downstream of TORC1. Nature. 552: 263-267. PMID 29186112 DOI: 10.1038/Nature25007 |
0.476 |
|
| 2017 |
Bolukbasi E, Khericha M, Regan JC, Ivanov DK, Adcott J, Dyson MC, Nespital T, Thornton JM, Alic N, Partridge L. Intestinal Fork Head Regulates Nutrient Absorption and Promotes Longevity. Cell Reports. 21: 641-653. PMID 29045833 DOI: 10.1016/J.Celrep.2017.09.042 |
0.786 |
|
| 2017 |
Tain LS, Sehlke R, Jain C, Chokkalingam M, Nagaraj N, Essers P, Rassner M, Grönke S, Froelich J, Dieterich C, Mann M, Alic N, Beyer A, Partridge L. A proteomic atlas of insulin signalling reveals tissue-specific mechanisms of longevity assurance. Molecular Systems Biology. 13: 939. PMID 28916541 DOI: 10.15252/Msb.20177663 |
0.642 |
|
| 2017 |
Dobson AJ, Ezcurra M, Flanagan CE, Summerfield AC, Piper MD, Gems D, Alic N. Nutritional Programming of Lifespan by FOXO Inhibition on Sugar-Rich Diets. Cell Reports. 18: 299-306. PMID 28076775 DOI: 10.1016/J.Celrep.2016.12.029 |
0.692 |
|
| 2016 |
Burnouf S, Grönke S, Augustin H, Dols J, Gorsky MK, Werner J, Kerr F, Alic N, Martinez P, Partridge L. Deletion of endogenous Tau proteins is not detrimental in Drosophila. Scientific Reports. 6: 23102. PMID 26976084 DOI: 10.1038/Srep23102 |
0.468 |
|
| 2016 |
Alic N. Of FOXes and Forgetful Worms. Cell Metabolism. 23: 403-4. PMID 26959183 DOI: 10.1016/J.Cmet.2016.02.013 |
0.373 |
|
| 2016 |
Afschar S, Toivonen JM, Hoffmann JM, Tain LS, Wieser D, Finlayson AJ, Driege Y, Alic N, Emran S, Stinn J, Froehlich J, Piper MD, Partridge L. Nuclear hormone receptor DHR96 mediates the resistance to xenobiotics but not the increased lifespan of insulin-mutant Drosophila. Proceedings of the National Academy of Sciences of the United States of America. PMID 26787908 DOI: 10.1073/Pnas.1515137113 |
0.742 |
|
| 2015 |
Slack C, Alic N, Partridge L. Could cancer drugs provide ammunition against ageing? Cell Cycle (Georgetown, Tex.). 0. PMID 26587873 DOI: 10.1080/15384101.2015.1118905 |
0.724 |
|
| 2015 |
Slack C, Alic N, Foley A, Cabecinha M, Hoddinott MP, Partridge L. The Ras-Erk-ETS-Signaling Pathway Is a Drug Target for Longevity. Cell. 162: 72-83. PMID 26119340 DOI: 10.1016/J.Cell.2015.06.023 |
0.77 |
|
| 2015 |
Alic N, Partridge L. Myc mouse and anti-ageing therapy. Trends in Endocrinology and Metabolism: Tem. 26: 163-4. PMID 25727046 DOI: 10.1016/J.Tem.2015.02.005 |
0.561 |
|
| 2015 |
Al Saud SN, Summerfield AC, Alic N. Ablation of insulin-producing cells prevents obesity but not premature mortality caused by a high-sugar diet in Drosophila. Proceedings. Biological Sciences / the Royal Society. 282: 20141720. PMID 25520354 DOI: 10.1098/Rspb.2014.1720 |
0.501 |
|
| 2014 |
Alic N, Giannakou ME, Papatheodorou I, Hoddinott MP, Andrews TD, Bolukbasi E, Partridge L. Interplay of dFOXO and two ETS-family transcription factors determines lifespan in Drosophila melanogaster. Plos Genetics. 10: e1004619. PMID 25232726 DOI: 10.1371/Journal.Pgen.1004619 |
0.56 |
|
| 2014 |
Alic N, Tullet JM, Niccoli T, Broughton S, Hoddinott MP, Slack C, Gems D, Partridge L. Cell-nonautonomous effects of dFOXO/DAF-16 in aging. Cell Reports. 6: 608-16. PMID 24508462 DOI: 10.1016/J.Celrep.2014.01.015 |
0.792 |
|
| 2012 |
Papatheodorou I, Ziehm M, Wieser D, Alic N, Partridge L, Thornton JM. Using answer set programming to integrate RNA expression with signalling pathway information to infer how mutations affect ageing. Plos One. 7: e50881. PMID 23251396 DOI: 10.1371/Journal.Pone.0050881 |
0.592 |
|
| 2012 |
Alic N, Hoddinott MP, Foley A, Slack C, Piper MD, Partridge L. Detrimental effects of RNAi: a cautionary note on its use in Drosophila ageing studies. Plos One. 7: e45367. PMID 23028964 DOI: 10.1371/Journal.Pone.0045367 |
0.76 |
|
| 2011 |
Alic N, Partridge L. Death and dessert: nutrient signalling pathways and ageing. Current Opinion in Cell Biology. 23: 738-43. PMID 21835601 DOI: 10.1016/J.Ceb.2011.07.006 |
0.612 |
|
| 2011 |
Alic N, Andrews TD, Giannakou ME, Papatheodorou I, Slack C, Hoddinott MP, Cochemé HM, Schuster EF, Thornton JM, Partridge L. Genome-wide dFOXO targets and topology of the transcriptomic response to stress and insulin signalling. Molecular Systems Biology. 7: 502. PMID 21694719 DOI: 10.1038/Msb.2011.36 |
0.779 |
|
| 2011 |
Alic N, Hoddinott MP, Vinti G, Partridge L. Lifespan extension by increased expression of the Drosophila homologue of the IGFBP7 tumour suppressor. Aging Cell. 10: 137-47. PMID 21108726 DOI: 10.1111/J.1474-9726.2010.00653.X |
0.605 |
|
| 2011 |
Partridge L, Alic N, Bjedov I, Piper MD. Ageing in Drosophila: the role of the insulin/Igf and TOR signalling network. Experimental Gerontology. 46: 376-81. PMID 20849947 DOI: 10.1016/J.Exger.2010.09.003 |
0.797 |
|
| 2010 |
Slack C, Werz C, Wieser D, Alic N, Foley A, Stocker H, Withers DJ, Thornton JM, Hafen E, Partridge L. Regulation of lifespan, metabolism, and stress responses by the Drosophila SH2B protein, Lnk. Plos Genetics. 6: e1000881. PMID 20333234 DOI: 10.1371/Journal.Pgen.1000881 |
0.792 |
|
| 2010 |
Broughton SJ, Slack C, Alic N, Metaxakis A, Bass TM, Driege Y, Partridge L. DILP-producing median neurosecretory cells in the Drosophila brain mediate the response of lifespan to nutrition. Aging Cell. 9: 336-46. PMID 20156206 DOI: 10.1111/J.1474-9726.2010.00558.X |
0.778 |
|
| 2009 |
Ikeya T, Broughton S, Alic N, Grandison R, Partridge L. The endosymbiont Wolbachia increases insulin/IGF-like signalling in Drosophila. Proceedings. Biological Sciences / the Royal Society. 276: 3799-807. PMID 19692410 DOI: 10.1098/Rspb.2009.0778 |
0.604 |
|
| 2008 |
Broughton S, Alic N, Slack C, Bass T, Ikeya T, Vinti G, Tommasi AM, Driege Y, Hafen E, Partridge L. Reduction of DILP2 in Drosophila triages a metabolic phenotype from lifespan revealing redundancy and compensation among DILPs. Plos One. 3: e3721. PMID 19005568 DOI: 10.1371/Journal.Pone.0003721 |
0.788 |
|
| 2008 |
Alic N, Partridge L. Stage debut for the elusive Drosophila insulin-like growth factor binding protein. Journal of Biology. 7: 18. PMID 18620552 DOI: 10.1186/Jbiol79 |
0.547 |
|
| 2007 |
Alic N, Partridge L. Antagonizing Methuselah to extend life span. Genome Biology. 8: 222. PMID 17764591 DOI: 10.1186/Gb-2007-8-8-222 |
0.469 |
|
| 2007 |
Alic N, Ayoub N, Landrieux E, Favry E, Baudouin-Cornu P, Riva M, Carles C. Selectivity and proofreading both contribute significantly to the fidelity of RNA polymerase III transcription. Proceedings of the National Academy of Sciences of the United States of America. 104: 10400-5. PMID 17553959 DOI: 10.1073/Pnas.0704116104 |
0.347 |
|
| 2006 |
Landrieux E, Alic N, Ducrot C, Acker J, Riva M, Carles C. A subcomplex of RNA polymerase III subunits involved in transcription termination and reinitiation Embo Journal. 25: 118-128. PMID 16362040 DOI: 10.1038/Sj.Emboj.7600915 |
0.312 |
|
| 2004 |
Alic N, Felder T, Temple MD, Gloeckner C, Higgins VJ, Briza P, Dawes IW. Genome-wide transcriptional responses to a lipid hydroperoxide: Adaptation occurs without induction of oxidant defenses Free Radical Biology and Medicine. 37: 23-35. PMID 15183192 DOI: 10.1016/J.Freeradbiomed.2004.04.014 |
0.321 |
|
| 2004 |
Thorpe GW, Fong CS, Alic N, Higgins VJ, Dawes IW. Cells have distinct mechanisms to maintain protection against different reactive oxygen species: Oxidative-stress-response genes Proceedings of the National Academy of Sciences of the United States of America. 101: 6564-6569. PMID 15087496 DOI: 10.1073/Pnas.0305888101 |
0.303 |
|
| 2003 |
Alic N, Higgins VJ, Pichova A, Breitenbach M, Dawes IW. Lipid Hydroperoxides Activate the Mitogen-activated Protein Kinase Mpk1p in Saccharomyces cerevisiae Journal of Biological Chemistry. 278: 41849-41855. PMID 12912987 DOI: 10.1074/Jbc.M307760200 |
0.348 |
|
| 2002 |
Higgins VJ, Alic N, Thorpe GW, Breitenbach M, Larsson V, Dawes IW. Phenotypic analysis of gene deletant strains for sensitivity to oxidative stress Yeast. 19: 203-214. PMID 11816028 DOI: 10.1002/Yea.811 |
0.304 |
|
| 2001 |
Alic N, Higgins VJ, Dawes IW. Identification of a Saccharomyces cerevisiae gene that is required for G1 arrest in response to the lipid oxidation product linoleic acid hydroperoxide Molecular Biology of the Cell. 12: 1801-1810. PMID 11408586 DOI: 10.1091/Mbc.12.6.1801 |
0.321 |
|
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