Sten Linnarsson - Publications

Affiliations: 
MBB Karolinska Institute, Stockholm, Sweden 

99 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Tian W, Zhou J, Bartlett A, Zeng Q, Liu H, Castanon RG, Kenworthy M, Altshul J, Valadon C, Aldridge A, Nery JR, Chen H, Xu J, Johnson ND, Lucero J, ... ... Linnarsson S, et al. Single-cell DNA methylation and 3D genome architecture in the human brain. Science (New York, N.Y.). 382: eadf5357. PMID 37824674 DOI: 10.1126/science.adf5357  0.354
2023 Siletti K, Hodge R, Mossi Albiach A, Lee KW, Ding SL, Hu L, Lönnerberg P, Bakken T, Casper T, Clark M, Dee N, Gloe J, Hirschstein D, Shapovalova NV, Keene CD, ... ... Linnarsson S, et al. Transcriptomic diversity of cell types across the adult human brain. Science (New York, N.Y.). 382: eadd7046. PMID 37824663 DOI: 10.1126/science.add7046  0.595
2023 Jorstad NL, Close J, Johansen N, Yanny AM, Barkan ER, Travaglini KJ, Bertagnolli D, Campos J, Casper T, Crichton K, Dee N, Ding SL, Gelfand E, Goldy J, Hirschstein D, ... ... Linnarsson S, et al. Transcriptomic cytoarchitecture reveals principles of human neocortex organization. Science (New York, N.Y.). 382: eadf6812. PMID 37824655 DOI: 10.1126/science.adf6812  0.302
2023 Braun E, Danan-Gotthold M, Borm LE, Lee KW, Vinsland E, Lönnerberg P, Hu L, Li X, He X, Andrusivová Ž, Lundeberg J, Barker RA, Arenas E, Sundström E, Linnarsson S. Comprehensive cell atlas of the first-trimester developing human brain. Science (New York, N.Y.). 382: eadf1226. PMID 37824650 DOI: 10.1126/science.adf1226  0.613
2023 Li YE, Preissl S, Miller M, Johnson ND, Wang Z, Jiao H, Zhu C, Wang Z, Xie Y, Poirion O, Kern C, Pinto-Duarte A, Tian W, Siletti K, Emerson N, ... ... Linnarsson S, et al. A comparative atlas of single-cell chromatin accessibility in the human brain. Science (New York, N.Y.). 382: eadf7044. PMID 37824643 DOI: 10.1126/science.adf7044  0.346
2023 Jorstad NL, Song JHT, Exposito-Alonso D, Suresh H, Castro-Pacheco N, Krienen FM, Yanny AM, Close J, Gelfand E, Long B, Seeman SC, Travaglini KJ, Basu S, Beaudin M, Bertagnolli D, ... ... Linnarsson S, et al. Comparative transcriptomics reveals human-specific cortical features. Science (New York, N.Y.). 382: eade9516. PMID 37824638 DOI: 10.1126/science.ade9516  0.308
2023 Munguba H, Nikouei K, Hochgerner H, Oberst P, Kouznetsova A, Ryge J, Muñoz-Manchado AB, Close J, Batista-Brito R, Linnarsson S, Hjerling-Leffler J. Transcriptional maintenance of cortical somatostatin interneuron subtype identity during migration. Neuron. PMID 37625400 DOI: 10.1016/j.neuron.2023.07.018  0.671
2023 Li X, Andrusivova Z, Czarnewski P, Langseth CM, Andersson A, Liu Y, Gyllborg D, Braun E, Larsson L, Hu L, Alekseenko Z, Lee H, Avenel C, Kallner HK, Åkesson E, ... ... Linnarsson S, et al. Profiling spatiotemporal gene expression of the developing human spinal cord and implications for ependymoma origin. Nature Neuroscience. PMID 37095395 DOI: 10.1038/s41593-023-01312-9  0.622
2023 Sountoulidis A, Marco Salas S, Braun E, Avenel C, Bergenstråhle J, Theelke J, Vicari M, Czarnewski P, Liontos A, Abalo X, Andrusivová Ž, Mirzazadeh R, Asp M, Li X, Hu L, ... ... Linnarsson S, et al. A topographic atlas defines developmental origins of cell heterogeneity in the human embryonic lung. Nature Cell Biology. PMID 36646791 DOI: 10.1038/s41556-022-01064-x  0.373
2022 Nishimura K, Yang S, Lee KW, Ásgrímsdóttir ES, Nikouei K, Paslawski W, Gnodde S, Lyu G, Hu L, Saltó C, Svenningsson P, Hjerling-Leffler J, Linnarsson S, Arenas E. Single-cell transcriptomics reveals correct developmental dynamics and high-quality midbrain cell types by improved hESC differentiation. Stem Cell Reports. PMID 36400027 DOI: 10.1016/j.stemcr.2022.10.016  0.782
2022 van Bruggen D, Pohl F, Langseth CM, Kukanja P, Lee H, Albiach AM, Kabbe M, Meijer M, Linnarsson S, Hilscher MM, Nilsson M, Sundström E, Castelo-Branco G. Developmental landscape of human forebrain at a single-cell level identifies early waves of oligodendrogenesis. Developmental Cell. PMID 35523173 DOI: 10.1016/j.devcel.2022.04.016  0.321
2022 Liu R, Pisco AO, Braun E, Linnarsson S, Zou J. Dynamical Systems Model of RNA Velocity Improves Inference of Single-cell Trajectory, Pseudo-time and Gene Regulation. Journal of Molecular Biology. 167606. PMID 35489382 DOI: 10.1016/j.jmb.2022.167606  0.325
2022 Luo C, Liu H, Xie F, Armand EJ, Siletti K, Bakken TE, Fang R, Doyle WI, Stuart T, Hodge RD, Hu L, Wang BA, Zhang Z, Preissl S, Lee DS, ... ... Linnarsson S, et al. Single nucleus multi-omics identifies human cortical cell regulatory genome diversity. Cell Genomics. 2. PMID 35419551 DOI: 10.1016/j.xgen.2022.100107  0.367
2021 Bakken TE, Jorstad NL, Hu Q, Lake BB, Tian W, Kalmbach BE, Crow M, Hodge RD, Krienen FM, Sorensen SA, Eggermont J, Yao Z, Aevermann BD, Aldridge AI, Bartlett A, ... ... Linnarsson S, et al. Comparative cellular analysis of motor cortex in human, marmoset and mouse. Nature. 598: 111-119. PMID 34616062 DOI: 10.1038/s41586-021-03465-8  0.39
2021 La Manno G, Siletti K, Furlan A, Gyllborg D, Vinsland E, Mossi Albiach A, Mattsson Langseth C, Khven I, Lederer AR, Dratva LM, Johnsson A, Nilsson M, Lönnerberg P, Linnarsson S. Molecular architecture of the developing mouse brain. Nature. 596: 92-96. PMID 34321664 DOI: 10.1038/s41586-021-03775-x  0.801
2020 Rajewsky N, Almouzni G, Gorski SA, Aerts S, Amit I, Bertero MG, Bock C, Bredenoord AL, Cavalli G, Chiocca S, Clevers H, De Strooper B, Eggert A, Ellenberg J, Fernández XM, ... ... Linnarsson S, et al. LifeTime and improving European healthcare through cell-based interceptive medicine. Nature. PMID 32894860 DOI: 10.1038/S41586-020-2715-9  0.347
2020 Toledo EM, Yang S, Gyllborg D, van Wijk KE, Sinha I, Varas-Godoy M, Grigsby CL, Lönnerberg P, Islam S, Steffensen KR, Linnarsson S, Arenas E. Srebf1 Controls Midbrain Dopaminergic Neurogenesis. Cell Reports. 31: 107601. PMID 32375051 DOI: 10.1016/J.Celrep.2020.107601  0.668
2019 Wang Y, Wu H, Fontanet P, Codeluppi S, Akkuratova N, Petitpré C, Xue-Franzén Y, Niederreither K, Sharma A, Da Silva F, Comai G, Agirman G, Palumberi D, Linnarsson S, Adameyko I, et al. A cell fitness selection model for neuronal survival during development. Nature Communications. 10: 4137. PMID 31515492 DOI: 10.1038/S41467-019-12119-3  0.803
2019 Goodridge JP, Jacobs B, Saetersmoen ML, Clement D, Hammer Q, Clancy T, Skarpen E, Brech A, Landskron J, Grimm C, Pfefferle A, Meza-Zepeda L, Lorenz S, Wiiger MT, Louch WE, ... ... Linnarsson S, et al. Remodeling of secretory lysosomes during education tunes functional potential in NK cells. Nature Communications. 10: 514. PMID 30705279 DOI: 10.1038/S41467-019-08384-X  0.343
2018 Codeluppi S, Borm LE, Zeisel A, La Manno G, van Lunteren JA, Svensson CI, Linnarsson S. Spatial organization of the somatosensory cortex revealed by osmFISH. Nature Methods. 15: 932-935. PMID 30377364 DOI: 10.1038/S41592-018-0175-Z  0.801
2018 Mezger A, Klemm S, Mann I, Brower K, Mir A, Bostick M, Farmer A, Fordyce P, Linnarsson S, Greenleaf W. High-throughput chromatin accessibility profiling at single-cell resolution. Nature Communications. 9: 3647. PMID 30194434 DOI: 10.1038/S41467-018-05887-X  0.418
2018 Muñoz-Manchado AB, Bengtsson Gonzales C, Zeisel A, Munguba H, Bekkouche B, Skene NG, Lönnerberg P, Ryge J, Harris KD, Linnarsson S, Hjerling-Leffler J. Diversity of Interneurons in the Dorsal Striatum Revealed by Single-Cell RNA Sequencing and PatchSeq. Cell Reports. 24: 2179-2190.e7. PMID 30134177 DOI: 10.1016/J.Celrep.2018.07.053  0.828
2018 Zeisel A, Hochgerner H, Lönnerberg P, Johnsson A, Memic F, van der Zwan J, Häring M, Braun E, Borm LE, La Manno G, Codeluppi S, Furlan A, Lee K, Skene N, Harris KD, ... ... Linnarsson S, et al. Molecular Architecture of the Mouse Nervous System. Cell. 174: 999-1014.e22. PMID 30096314 DOI: 10.1016/J.Cell.2018.06.021  0.809
2018 La Manno G, Soldatov R, Zeisel A, Braun E, Hochgerner H, Petukhov V, Lidschreiber K, Kastriti ME, Lönnerberg P, Furlan A, Fan J, Borm LE, Liu Z, van Bruggen D, Guo J, ... ... Linnarsson S, et al. RNA velocity of single cells. Nature. PMID 30089906 DOI: 10.1038/S41586-018-0414-6  0.793
2018 Savage JE, Jansen PR, Stringer S, Watanabe K, Bryois J, de Leeuw CA, Nagel M, Awasthi S, Barr PB, Coleman JRI, Grasby KL, Hammerschlag AR, Kaminski JA, Karlsson R, Krapohl E, ... ... Linnarsson S, et al. Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence. Nature Genetics. PMID 29942086 DOI: 10.1038/S41588-018-0152-6  0.667
2018 Nagel M, Jansen PR, Stringer S, Watanabe K, de Leeuw CA, Bryois J, Savage JE, Hammerschlag AR, Skene NG, Muñoz-Manchado AB, White T, Tiemeier H, Linnarsson S, Hjerling-Leffler J, et al. Meta-analysis of genome-wide association studies for neuroticism in 449,484 individuals identifies novel genetic loci and pathways. Nature Genetics. PMID 29942085 DOI: 10.1038/S41588-018-0151-7  0.666
2018 Harris KD, Hochgerner H, Skene NG, Magno L, Katona L, Bengtsson Gonzales C, Somogyi P, Kessaris N, Linnarsson S, Hjerling-Leffler J. Classes and continua of hippocampal CA1 inhibitory neurons revealed by single-cell transcriptomics. Plos Biology. 16: e2006387. PMID 29912866 DOI: 10.1371/Journal.Pbio.2006387  0.728
2018 Skene NG, Bryois J, Bakken TE, Breen G, Crowley JJ, Gaspar HA, Giusti-Rodriguez P, Hodge RD, Miller JA, Muñoz-Manchado AB, O'Donovan MC, Owen MJ, Pardiñas AF, Ryge J, Walters JTR, ... Linnarsson S, et al. Genetic identification of brain cell types underlying schizophrenia. Nature Genetics. PMID 29785013 DOI: 10.1038/s41588-018-0129-5  0.715
2018 Häring M, Zeisel A, Hochgerner H, Rinwa P, Jakobsson JET, Lönnerberg P, La Manno G, Sharma N, Borgius L, Kiehn O, Lagerström MC, Linnarsson S, Ernfors P. Neuronal atlas of the dorsal horn defines its architecture and links sensory input to transcriptional cell types. Nature Neuroscience. PMID 29686262 DOI: 10.1038/S41593-018-0141-1  0.807
2018 Coleman JRI, Bryois J, Gaspar HA, Jansen PR, Savage JE, Skene N, Plomin R, Muñoz-Manchado AB, Linnarsson S, Crawford G, Hjerling-Leffler J, Sullivan PF, Posthuma D, Breen G. Biological annotation of genetic loci associated with intelligence in a meta-analysis of 87,740 individuals. Molecular Psychiatry. PMID 29520040 DOI: 10.1038/S41380-018-0040-6  0.721
2018 Hochgerner H, Zeisel A, Lönnerberg P, Linnarsson S. Conserved properties of dentate gyrus neurogenesis across postnatal development revealed by single-cell RNA sequencing. Nature Neuroscience. PMID 29335606 DOI: 10.1038/S41593-017-0056-2  0.753
2018 Savage JE, Jansen PR, Stringer S, Watanabe K, Bryois J, Leeuw CAd, Nagel M, Awasthi S, Barr PB, Coleman JRI, Grasby KL, Hammerschlag AR, Kaminski J, Karlsson R, Krapohl E, ... ... Linnarsson S, et al. GWAS meta-analysis (N=279,930) identifies new genes and functional links to general cognitive ability Human Genomics. 12. DOI: 10.1186/S40246-018-0138-6  0.619
2017 Nguyen HT, Bryois J, Kim A, Dobbyn A, Huckins LM, Munoz-Manchado AB, Ruderfer DM, Genovese G, Fromer M, Xu X, Pinto D, Linnarsson S, Verhage M, Smit AB, Hjerling-Leffler J, et al. Integrated Bayesian analysis of rare exonic variants to identify risk genes for schizophrenia and neurodevelopmental disorders. Genome Medicine. 9: 114. PMID 29262854 DOI: 10.1186/S13073-017-0497-Y  0.616
2017 Boström J, Sramkova Z, Salašová A, Johard H, Mahdessian D, Fedr R, Marks C, Medalová J, Souček K, Lundberg E, Linnarsson S, Bryja V, Sekyrova P, Altun M, Andäng M. Comparative cell cycle transcriptomics reveals synchronization of developmental transcription factor networks in cancer cells. Plos One. 12: e0188772. PMID 29228002 DOI: 10.1371/Journal.Pone.0188772  0.437
2017 Regev A, Teichmann SA, Lander ES, Amit I, Benoist C, Birney E, Bodenmiller B, Campbell PJ, Carninci P, Clatworthy M, Clevers H, Deplancke B, Dunham I, Eberwine J, Eils R, ... ... Linnarsson S, et al. Science Forum: The Human Cell Atlas. Elife. 6. PMID 29206104 DOI: 10.7554/Elife.27041  0.431
2017 Hochgerner H, Lönnerberg P, Hodge R, Mikes J, Heskol A, Hubschle H, Lin P, Picelli S, La Manno G, Ratz M, Dunne J, Husain S, Lein E, Srinivasan M, Zeisel A, ... Linnarsson S, et al. STRT-seq-2i: dual-index 5' single cell and nucleus RNA-seq on an addressable microwell array. Scientific Reports. 7: 16327. PMID 29180631 DOI: 10.1038/S41598-017-16546-4  0.808
2017 Ruetz T, Pfisterer U, Di Stefano B, Ashmore J, Beniazza M, Tian TV, Kaemena DF, Tosti L, Tan W, Manning JR, Chantzoura E, Ottosson DR, Collombet S, Johnsson A, Cohen E, ... ... Linnarsson S, et al. Constitutively Active SMAD2/3 Are Broad-Scope Potentiators of Transcription-Factor-Mediated Cellular Reprogramming. Cell Stem Cell. 21: 791-805.e9. PMID 29174331 DOI: 10.1016/J.Stem.2017.10.013  0.426
2017 Lein E, Borm LE, Linnarsson S. The promise of spatial transcriptomics for neuroscience in the era of molecular cell typing. Science (New York, N.Y.). 358: 64-69. PMID 28983044 DOI: 10.1126/Science.Aan6827  0.462
2017 Lake BB, Codeluppi S, Yung YC, Gao D, Chun J, Kharchenko PV, Linnarsson S, Zhang K. A comparative strategy for single-nucleus and single-cell transcriptomes confirms accuracy in predicted cell-type expression from nuclear RNA. Scientific Reports. 7: 6031. PMID 28729663 DOI: 10.1038/S41598-017-04426-W  0.534
2017 Karlsson K, Lönnerberg P, Linnarsson S. Alternative TSSs are co-regulated in single cells in the mouse brain. Molecular Systems Biology. 13: 930. PMID 28495919 DOI: 10.15252/Msb.20167374  0.828
2017 di Val Cervo PR, Romanov RA, Spigolon G, Masini D, Martín-Montañez E, Toledo EM, La Manno G, Feyder M, Pifl C, Ng YH, Sánchez SP, Linnarsson S, Wernig M, Harkany T, Fisone G, et al. Induction of functional dopamine neurons from human astrocytes in vitro and mouse astrocytes in a Parkinson's disease model. Nature Biotechnology. PMID 28398344 DOI: 10.1038/Nbt.3835  0.781
2017 Karlsson K, Linnarsson S. Single-cell mRNA isoform diversity in the mouse brain. Bmc Genomics. 18: 126. PMID 28158971 DOI: 10.1186/S12864-017-3528-6  0.804
2017 Niklasson M, Maddalo G, Sramkova Z, Mutlu E, Wee S, Sekyrova P, Schmidt L, Fritz N, Dehnisch I, Kyriatzis G, Krafcikova M, Carson BB, Feenstra J, Marinescu VD, Segerman A, ... ... Linnarsson S, et al. Membrane-depolarizing channel blockers induce selective glioma cell death by impairing nutrient transport and unfolded protein/amino acid responses. Cancer Research. PMID 28087597 DOI: 10.1158/0008-5472.Can-16-2274  0.326
2017 Regev A, Teichmann SA, Lander ES, Amit I, Benoist C, Birney E, Bodenmiller B, Campbell P, Carninci P, Clatworthy M, Clevers H, Deplancke B, Dunham I, Eberwine J, Eils R, ... ... Linnarsson S, et al. Author response: The Human Cell Atlas Elife. DOI: 10.7554/Elife.27041.011  0.319
2017 Morarach K, Memic F, Zeisel A, Hochgerner H, Marklund U, Linnarsson S. Single-cell molecular interrogation of enteric nervous system development Mechanisms of Development. 145: S67. DOI: 10.1016/J.Mod.2017.04.151  0.734
2016 Romanov RA, Zeisel A, Bakker J, Girach F, Hellysaz A, Tomer R, Alpár A, Mulder J, Clotman F, Keimpema E, Hsueh B, Crow AK, Martens H, Schwindling C, Calvigioni D, ... ... Linnarsson S, et al. Molecular interrogation of hypothalamic organization reveals distinct dopamine neuronal subtypes. Nature Neuroscience. PMID 27991900 DOI: 10.1038/Nn.4462  0.732
2016 La Manno G, Gyllborg D, Codeluppi S, Nishimura K, Salto C, Zeisel A, Borm LE, Stott SR, Toledo EM, Villaescusa JC, Lönnerberg P, Ryge J, Barker RA, Arenas E, Linnarsson S. Molecular Diversity of Midbrain Development in Mouse, Human, and Stem Cells. Cell. 167: 566-580.e19. PMID 27716510 DOI: 10.1016/J.Cell.2016.09.027  0.829
2016 Joost S, Zeisel A, Jacob T, Sun X, La Manno G, Lönnerberg P, Linnarsson S, Kasper M. Single-Cell Transcriptomics Reveals that Differentiation and Spatial Signatures Shape Epidermal and Hair Follicle Heterogeneity. Cell Systems. PMID 27641957 DOI: 10.1016/J.Cels.2016.08.010  0.817
2016 Jouhilahti EM, Madissoon E, Vesterlund L, Töhönen V, Krjutŝkov K, Reyes AP, Petropoulos S, Månsson R, Linnarsson S, Bürglin T, Lanner F, Hovatta O, Katayama S, Kere J. The human PRD-like homeobox gene LEUTX has a central role in embryo genome activation. Development (Cambridge, England). PMID 27578796 DOI: 10.1242/Dev.134510  0.364
2016 Furlan A, La Manno G, Lübke M, Häring M, Abdo H, Hochgerner H, Kupari J, Usoskin D, Airaksinen MS, Oliver G, Linnarsson S, Ernfors P. Visceral motor neuron diversity delineates a cellular basis for nipple- and pilo-erection muscle control. Nature Neuroscience. PMID 27571008 DOI: 10.1038/Nn.4376  0.8
2016 Madissoon E, Jouhilahti EM, Vesterlund L, Töhönen V, Krjutškov K, Petropoulous S, Einarsdottir E, Linnarsson S, Lanner F, Månsson R, Hovatta O, Bürglin TR, Katayama S, Kere J. Characterization and target genes of nine human PRD-like homeobox domain genes expressed exclusively in early embryos. Scientific Reports. 6: 28995. PMID 27412763 DOI: 10.1038/Srep28995  0.363
2016 Ståhl PL, Salmén F, Vickovic S, Lundmark A, Navarro JF, Magnusson J, Giacomello S, Asp M, Westholm JO, Huss M, Mollbrink A, Linnarsson S, Codeluppi S, Borg Å, Pontén F, et al. Visualization and analysis of gene expression in tissue sections by spatial transcriptomics. Science (New York, N.Y.). 353: 78-82. PMID 27365449 DOI: 10.1126/Science.Aaf2403  0.317
2016 Villaescusa JC, Li B, Toledo EM, Rivetti di Val Cervo P, Yang S, Stott SR, Kaiser K, Islam S, Gyllborg D, Laguna-Goya R, Landreh M, Lönnerberg P, Falk A, Bergman T, Barker RA, ... Linnarsson S, et al. A PBX1 transcriptional network controls dopaminergic neuron development and is impaired in Parkinson's disease. The Embo Journal. PMID 27354364 DOI: 10.15252/Embj.201593725  0.69
2016 Marques S, Zeisel A, Codeluppi S, van Bruggen D, Mendanha Falcão A, Xiao L, Li H, Häring M, Hochgerner H, Romanov RA, Gyllborg D, Muñoz-Manchado AB, La Manno G, Lönnerberg P, Floriddia EM, ... ... Linnarsson S, et al. Oligodendrocyte heterogeneity in the mouse juvenile and adult central nervous system. Science (New York, N.Y.). 352: 1326-9. PMID 27284195 DOI: 10.1126/Science.Aaf6463  0.778
2016 Linnarsson S, Teichmann SA. Single-cell genomics: coming of age. Genome Biology. 17: 97. PMID 27160975 DOI: 10.1186/S13059-016-0960-X  0.476
2016 Petropoulos S, Edsgärd D, Reinius B, Deng Q, Panula SP, Codeluppi S, Plaza Reyes A, Linnarsson S, Sandberg R, Lanner F. Single-Cell RNA-Seq Reveals Lineage and X Chromosome Dynamics in Human Preimplantation Embryos. Cell. PMID 27062923 DOI: 10.1016/J.Cell.2016.03.023  0.43
2016 Tervaniemi MH, Katayama S, Skoog T, Siitonen HA, Vuola J, Nuutila K, Sormunen R, Johnsson A, Linnarsson S, Suomela S, Kankuri E, Kere J, Elomaa O. NOD-like receptor signaling and inflammasome-related pathways are highlighted in psoriatic epidermis. Scientific Reports. 6: 22745. PMID 26976200 DOI: 10.1038/Srep22745  0.304
2016 Heshmati Y, Turköz G, Harisankar A, Linnarsson S, Dimitriou M, Sinha I, Lehmann S, Qian H, Walfridsson J. Identification of CHD4 As a Potential Therapeutic Target of Acute Myeloid Leukemia Blood. 128: 1648-1648. DOI: 10.1182/Blood.V128.22.1648.1648  0.4
2015 Fuzik J, Zeisel A, Máté Z, Calvigioni D, Yanagawa Y, Szabó G, Linnarsson S, Harkany T. Integration of electrophysiological recordings with single-cell RNA-seq data identifies neuronal subtypes. Nature Biotechnology. PMID 26689544 DOI: 10.1038/Nbt.3443  0.771
2015 Füllgrabe A, Joost S, Are A, Jacob T, Sivan U, Haegebarth A, Linnarsson S, Simons BD, Clevers H, Toftgård R, Kasper M. Dynamics of Lgr6(+) Progenitor Cells in the Hair Follicle, Sebaceous Gland, and Interfollicular Epidermis. Stem Cell Reports. PMID 26607954 DOI: 10.1016/J.Stemcr.2015.09.013  0.398
2015 Linnarsson S. NEUROSCIENCE. A tree of the human brain. Science (New York, N.Y.). 350: 37. PMID 26430106 DOI: 10.1126/Science.Aad2792  0.41
2015 Töhönen V, Katayama S, Vesterlund L, Jouhilahti EM, Sheikhi M, Madissoon E, Filippini-Cattaneo G, Jaconi M, Johnsson A, Bürglin TR, Linnarsson S, Hovatta O, Kere J. Novel PRD-like homeodomain transcription factors and retrotransposon elements in early human development. Nature Communications. 6: 8207. PMID 26360614 DOI: 10.1038/Ncomms9207  0.427
2015 Linnarsson S. Sequencing Single Cells Reveals Sequential Stem Cell States. Cell Stem Cell. 17: 251-2. PMID 26340522 DOI: 10.1016/J.Stem.2015.08.016  0.396
2015 Chantzoura E, Skylaki S, Menendez S, Kim SI, Johnsson A, Linnarsson S, Woltjen K, Chambers I, Kaji K. Reprogramming Roadblocks Are System Dependent. Stem Cell Reports. 5: 350-64. PMID 26278041 DOI: 10.1016/J.Stemcr.2015.07.007  0.31
2015 Katayama S, Skoog T, Jouhilahti EM, Siitonen HA, Nuutila K, Tervaniemi MH, Vuola J, Johnsson A, Lönnerberg P, Linnarsson S, Elomaa O, Kankuri E, Kere J. Gene expression analysis of skin grafts and cultured keratinocytes using synthetic RNA normalization reveals insights into differentiation and growth control. Bmc Genomics. 16: 476. PMID 26108968 DOI: 10.1186/S12864-015-1671-5  0.408
2015 Zeisel A, Muñoz-Manchado AB, Codeluppi S, Lönnerberg P, La Manno G, Juréus A, Marques S, Munguba H, He L, Betsholtz C, Rolny C, Castelo-Branco G, Hjerling-Leffler J, Linnarsson S. Brain structure. Cell types in the mouse cortex and hippocampus revealed by single-cell RNA-seq. Science (New York, N.Y.). 347: 1138-42. PMID 25700174 DOI: 10.1126/Science.Aaa1934  0.822
2015 Stäubert C, Bhuiyan H, Lindahl A, Broom OJ, Zhu Y, Islam S, Linnarsson S, Lehtiö J, Nordström A. Rewired metabolism in drug-resistant leukemia cells: a metabolic switch hallmarked by reduced dependence on exogenous glutamine. The Journal of Biological Chemistry. 290: 8348-59. PMID 25697355 DOI: 10.1074/Jbc.M114.618769  0.557
2015 Karlsson K, Sahlin E, Iwarsson E, Westgren M, Nordenskjöld M, Linnarsson S. Amplification-free sequencing of cell-free DNA for prenatal non-invasive diagnosis of chromosomal aberrations. Genomics. 105: 150-8. PMID 25543032 DOI: 10.1016/J.Ygeno.2014.12.005  0.771
2015 Romanov RA, Alpár A, Zhang MD, Zeisel A, Calas A, Landry M, Fuszard M, Shirran SL, Schnell R, Dobolyi Á, Oláh M, Spence L, Mulder J, Martens H, Palkovits M, ... ... Linnarsson S, et al. A secretagogin locus of the mammalian hypothalamus controls stress hormone release. The Embo Journal. 34: 36-54. PMID 25430741 DOI: 10.15252/Embj.201488977  0.687
2015 Usoskin D, Furlan A, Islam S, Abdo H, Lönnerberg P, Lou D, Hjerling-Leffler J, Haeggström J, Kharchenko O, Kharchenko PV, Linnarsson S, Ernfors P. Unbiased classification of sensory neuron types by large-scale single-cell RNA sequencing. Nature Neuroscience. 18: 145-53. PMID 25420068 DOI: 10.1038/Nn.3881  0.823
2015 Woll P, Kjällquist U, Chowdhury O, Doolittle H, Wedge D, Thongjuea S, Erlandsson R, Ngara M, Anderson K, Deng Q, Mead A, Stenson L, Giustacchini A, Duarte S, Giannoulatou E, ... ... Linnarsson S, et al. Myelodysplastic Syndromes Are Propagated by Rare and Distinct Human Cancer Stem Cells In Vivo Cancer Cell. 27: 603-605. DOI: 10.1016/J.Ccell.2015.03.003  0.316
2014 Wee S, Niklasson M, Marinescu VD, Segerman A, Schmidt L, Hermansson A, Dirks P, Forsberg-Nilsson K, Westermark B, Uhrbom L, Linnarsson S, Nelander S, Andäng M. Selective calcium sensitivity in immature glioma cancer stem cells. Plos One. 9: e115698. PMID 25531110 DOI: 10.1371/Journal.Pone.0115698  0.335
2014 Zechel S, Zajac P, Lönnerberg P, Ibáñez CF, Linnarsson S. Topographical transcriptome mapping of the mouse medial ganglionic eminence by spatially resolved RNA-seq. Genome Biology. 15: 486. PMID 25344199 DOI: 10.1186/S13059-014-0486-Z  0.436
2014 Woll PS, Kjällquist U, Chowdhury O, Doolittle H, Wedge DC, Thongjuea S, Erlandsson R, Ngara M, Anderson K, Deng Q, Mead AJ, Stenson L, Giustacchini A, Duarte S, Giannoulatou E, ... ... Linnarsson S, et al. Myelodysplastic syndromes are propagated by rare and distinct human cancer stem cells in vivo. Cancer Cell. 25: 794-808. PMID 24835589 DOI: 10.1016/J.Ccr.2014.03.036  0.366
2014 Islam S, Zeisel A, Joost S, La Manno G, Zajac P, Kasper M, Lönnerberg P, Linnarsson S. Quantitative single-cell RNA-seq with unique molecular identifiers. Nature Methods. 11: 163-6. PMID 24363023 DOI: 10.1038/Nmeth.2772  0.8
2014 Chowdhury O, Woll PS, Kjällquist U, Doolittle H, Erlandsson R, Anderson K, Dybedal I, Mead A, Clark S, Holm MS, Hokland P, Nilsson L, Linnarsson S, Hellstrom-Lindberg E, Jacobsen SEW. Characterisation of the Stem and Progenitor Cell Hierarchy in Patients with CMML Blood. 124: 1896-1896. DOI: 10.1182/Blood.V124.21.1896.1896  0.355
2013 Zajac P, Islam S, Hochgerner H, Lönnerberg P, Linnarsson S. Base preferences in non-templated nucleotide incorporation by MMLV-derived reverse transcriptases. Plos One. 8: e85270. PMID 24392002 DOI: 10.1371/Journal.Pone.0085270  0.576
2013 Katayama S, Töhönen V, Linnarsson S, Kere J. SAMstrt: statistical test for differential expression in single-cell transcriptome with spike-in normalization. Bioinformatics (Oxford, England). 29: 2943-5. PMID 23995393 DOI: 10.1093/Bioinformatics/Btt511  0.47
2013 Abdelhady S, Kitambi SS, Lundin V, Aufschnaiter R, Sekyrova P, Sinha I, Lundgren KT, Castelo-Branco G, Linnarsson S, Wedlich-Söldner R, Teixeira A, Andäng M. Erg channel is critical in controlling cell volume during cell cycle in embryonic stem cells. Plos One. 8: e72409. PMID 23936540 DOI: 10.1371/Journal.Pone.0072409  0.406
2013 Shapiro E, Biezuner T, Linnarsson S. Single-cell sequencing-based technologies will revolutionize whole-organism science. Nature Reviews. Genetics. 14: 618-30. PMID 23897237 DOI: 10.1038/Nrg3542  0.428
2013 O'Malley J, Skylaki S, Iwabuchi KA, Chantzoura E, Ruetz T, Johnsson A, Tomlinson SR, Linnarsson S, Kaji K. High-resolution analysis with novel cell-surface markers identifies routes to iPS cells. Nature. 499: 88-91. PMID 23728301 DOI: 10.1038/Nature12243  0.443
2013 Linnarsson S. Single-cell biology meeting marks rebirth of an old science. Genome Biology. 14: 305. PMID 23607893 DOI: 10.1186/Gb-2013-14-4-305  0.378
2013 Woll P, Kjällquist U, Chowdhury O, Erlandsson R, Doolittle H, Ngara M, Anderson K, Giannoulatou E, Taylor S, Deng Q, Mead AJ, Scharenberg C, Mortera-Blanco T, Macaulay IC, Clark s, ... ... Linnarsson S, et al. Diverse Genetic Lesions In Myelodysplastic Syndromes Originate Exclusively In Rare MDS Stem Cells Blood. 122: 4195-4195. DOI: 10.1182/Blood.V122.21.4195.4195  0.39
2012 Lallemend F, Sterzenbach U, Hadjab-Lallemend S, Aquino JB, Castelo-Branco G, Sinha I, Villaescusa JC, Levanon D, Wang Y, Franck MC, Kharchenko O, Adameyko I, Linnarsson S, Groner Y, Turner E, et al. Positional differences of axon growth rates between sensory neurons encoded by Runx3. The Embo Journal. 31: 3718-29. PMID 22903063 DOI: 10.1038/Emboj.2012.228  0.783
2012 Jääger K, Islam S, Zajac P, Linnarsson S, Neuman T. RNA-seq analysis reveals different dynamics of differentiation of human dermis- and adipose-derived stromal stem cells. Plos One. 7: e38833. PMID 22723894 DOI: 10.1371/Journal.Pone.0038833  0.604
2012 Islam S, Kjällquist U, Moliner A, Zajac P, Fan JB, Lönnerberg P, Linnarsson S. Highly multiplexed and strand-specific single-cell RNA 5' end sequencing. Nature Protocols. 7: 813-28. PMID 22481528 DOI: 10.1038/Nprot.2012.022  0.63
2012 Fan JB, Chen J, April CS, Fisher JS, Klotzle B, Bibikova M, Kaper F, Ronaghi M, Linnarsson S, Ota T, Chien J, Laurent LC, Loring JF, Nisperos SV, Chen GY, et al. Highly parallel genome-wide expression analysis of single mammalian cells. Plos One. 7: e30794. PMID 22347404 DOI: 10.1371/Journal.Pone.0030794  0.456
2012 Kivioja T, Vähärautio A, Karlsson K, Bonke M, Enge M, Linnarsson S, Taipale J. Counting absolute numbers of molecules using unique molecular identifiers. Nature Methods. 9: 72-4. PMID 22101854 DOI: 10.1038/Nmeth.1778  0.781
2011 Islam S, Kjällquist U, Moliner A, Zajac P, Fan JB, Lönnerberg P, Linnarsson S. Characterization of the single-cell transcriptional landscape by highly multiplex RNA-seq. Genome Research. 21: 1160-7. PMID 21543516 DOI: 10.1101/Gr.110882.110  0.668
2010 Usoskin D, Zilberter M, Linnarsson S, Hjerling-Leffler J, Uhlén P, Harkany T, Ernfors P. En masse in vitro functional profiling of the axonal mechanosensitivity of sensory neurons. Proceedings of the National Academy of Sciences of the United States of America. 107: 16336-41. PMID 20736349 DOI: 10.1073/Pnas.0914705107  0.752
2010 Linnarsson S. Recent advances in DNA sequencing methods - general principles of sample preparation. Experimental Cell Research. 316: 1339-43. PMID 20211618 DOI: 10.1016/J.Yexcr.2010.02.036  0.3
2010 Fan J, Chen J, April C, Klotzle B, Royce T, Cann G, Talasaz AH, Islam S, Kjallquist U, Linnarsson S. Abstract 1149: Genetic analysis of single cells Cancer Research. 70: 1149-1149. DOI: 10.1158/1538-7445.Am10-1149  0.64
2009 Usoskin D, Linnarsson S, Uhlen P, Ernfors P. 324 DEVELOPMENT OF A NOVEL IN VITRO SYSTEM FOR THE STUDY OF MECHANORECEPTIVE COMPONENT IN NEUROPATHIC PAIN European Journal of Pain. 13: S99. DOI: 10.1016/S1090-3801(09)60327-X  0.494
2004 Metsis A, Andersson U, Baurén G, Ernfors P, Lönnerberg P, Montelius A, Oldin M, Pihlak A, Linnarsson S. Whole-genome expression profiling through fragment display and combinatorial gene identification. Nucleic Acids Research. 32: e127. PMID 15356287 DOI: 10.1093/Nar/Gnh126  0.581
2001 Linnarsson S, Mikaels A, Baudet C, Ernfors P. Activation by GDNF of a transcriptional program repressing neurite growth in dorsal root ganglia. Proceedings of the National Academy of Sciences of the United States of America. 98: 14681-6. PMID 11724954 DOI: 10.1073/Pnas.251548898  0.64
2000 Linnarsson S, Willson CA, Ernfors P. Cell death in regenerating populations of neurons in BDNF mutant mice. Brain Research. Molecular Brain Research. 75: 61-9. PMID 10648888 DOI: 10.1016/S0169-328X(99)00295-8  0.635
1998 Ringstedt T, Linnarsson S, Wagner J, Lendahl U, Kokaia Z, Arenas E, Ernfors P, Ibáñez CF. BDNF regulates reelin expression and Cajal-Retzius cell development in the cerebral cortex. Neuron. 21: 305-15. PMID 9728912 DOI: 10.1016/S0896-6273(00)80540-1  0.696
1997 Linnarsson S, Björklund A, Ernfors P. Learning deficit in BDNF mutant mice. The European Journal of Neuroscience. 9: 2581-7. PMID 9517463 DOI: 10.1111/J.1460-9568.1997.Tb01687.X  0.541
1995 Kucera J, Fan G, Jaenisch R, Linnarsson S, Ernfors P. Dependence of developing group Ia afferents on neurotrophin-3. The Journal of Comparative Neurology. 363: 307-20. PMID 8642077 DOI: 10.1002/Cne.903630211  0.574
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