Thomas Jespersen - Publications

Affiliations: 
Biomedical Sciences University of Copenhagen, København, Denmark 

107 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Nissen SD, Weis R, Krag-Andersen EK, Hesselkilde EM, Isaksen JL, Carstensen H, Kanters JK, Linz D, Sanders P, Hopster-Iversen C, Jespersen T, Pehrson S, Buhl R. Electrocardiographic characteristics of trained and untrained standardbred racehorses. Journal of Veterinary Internal Medicine. 36: 1119-1130. PMID 35488721 DOI: 10.1111/jvim.16427  0.486
2022 Paludan-Müller C, Larsen S, Ahlberg G, Andreasen L, Monfort LM, Svendsen JH, Jespersen T, Bundgaard H, Kanters JK, Olesen MS. Clinical Implications of Loss-of-Function Variants in 169 610 Exomes Representing the General Population. Circulation. Genomic and Precision Medicine. CIRCGEN121003574. PMID 35103494 DOI: 10.1161/CIRCGEN.121.003574  0.433
2021 Lubberding AF, Zhang J, Lundh M, Nielsen TS, Søndergaard MS, Villadsen M, Skovhøj EZ, Boer GA, Hansen JB, Thomsen MB, Treebak JT, Holst JJ, Kanters JK, Mandrup-Poulsen T, Jespersen T, et al. Age-dependent transition from islet insulin hypersecretion to hyposecretion in mice with the long QT-syndrome loss-of-function mutation Kcnq1-A340V. Scientific Reports. 11: 12253. PMID 34112814 DOI: 10.1038/s41598-021-90452-8  0.494
2021 Gatta G, Sobota V, Citerni C, Diness JG, Sørensen US, Jespersen T, Bentzen BH, Zeemering S, Kuiper M, Verheule S, Schotten U, van Hunnik A. Effective termination of atrial fibrillation by SK channel inhibition is associated with a sudden organization of fibrillatory conduction. Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups On Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology. PMID 34080619 DOI: 10.1093/europace/euab125  0.375
2021 van der Horst J, Rognant S, Abbott GW, Ozhathil LC, Hägglund P, Barrese V, Chuang CY, Jespersen T, Davies MJ, Greenwood IA, Gourdon P, Aalkjær C, Jepps TA. Dynein regulates Kv7.4 channel trafficking from the cell membrane. The Journal of General Physiology. 153. PMID 33533890 DOI: 10.1085/jgp.202012760  0.382
2020 Hesselkilde EM, Isaksen JL, Petersen BV, Carstensen H, Jespersen T, Pehrson S, Kanters JK, Buhl R. A novel approach for obtaining 12-lead electrocardiograms in horses. Journal of Veterinary Internal Medicine. PMID 33274799 DOI: 10.1111/jvim.15980  0.471
2020 Saljic A, Soattin L, Trachsel DS, Boddum K, Jespersen T. In vivo knockdown of SK3 channels using antisense oligonucleotides protects against atrial fibrillation in rats. Journal of Molecular and Cellular Cardiology. 147: 18-26. PMID 32768409 DOI: 10.1016/J.Yjmcc.2020.07.011  0.475
2020 Soattin L, Lubberding AF, Bentzen BH, Christ T, Jespersen T. Inhibition of Adenosine Pathway Alters Atrial Electrophysiology and Prevents Atrial Fibrillation. Frontiers in Physiology. 11: 493. PMID 32595514 DOI: 10.3389/Fphys.2020.00493  0.406
2020 Linz B, Rombouts K, Thostrup AH, Hohl M, Wirth K, Linz D, Jespersen T. 741Pharmacological inhibition of the acetylcholine-regulated potassium channel (IK,ACh) prevents atrial arrhythmogenic changes in a rat model for obstructive sleep apnea Europace. 22. DOI: 10.1093/Europace/Euaa162.052  0.383
2019 Saljic A, Muthukumarasamy KM, la Cour JM, Boddum K, Grunnet M, Berchtold MW, Jespersen T. Impact of arrhythmogenic calmodulin variants on small conductance Ca -activated K (SK3) channels. Physiological Reports. 7: e14210. PMID 31587513 DOI: 10.14814/Phy2.14210  0.513
2019 Lubberding AF, Sattler SM, Grunnet M, Sørensen US, Tfelt-Hansen J, Jespersen T. Arrhythmia development during inhibition of small-conductance calcium-activated potassium channels in acute myocardial infarction in a porcine model. Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups On Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology. PMID 31408093 DOI: 10.1093/europace/euz223  0.372
2019 Kirchhoff JE, Skarsfeldt MA, Muthukumarasamy KM, Simó-Vicens R, Bomholtz SH, Abildgaard L, Jespersen T, Sørensen US, Grunnet M, Bentzen BH, Diness JG. The K2 Channel Inhibitor AP14145, But Not Dofetilide or Ondansetron, Provides Functional Atrial Selectivity in Guinea Pig Hearts. Frontiers in Pharmacology. 10: 668. PMID 31275147 DOI: 10.3389/fphar.2019.00668  0.363
2018 Carstensen H, Hesselkilde EZ, Fenner M, Loft-Andersen AV, Flethøj M, Kanters JK, Sattler SM, Tfelt-Hansen J, Pehrson S, Jespersen T, Buhl R. Time-dependent antiarrhythmic effects of flecainide on induced atrial fibrillation in horses. Journal of Veterinary Internal Medicine. PMID 30133839 DOI: 10.1111/Jvim.15287  0.482
2018 Skibsbye L, Bengaard AK, Uldum-Nielsen AM, Boddum K, Christ T, Jespersen T. Inhibition of Small Conductance Calcium-Activated Potassium (SK) Channels Prevents Arrhythmias in Rat Atria During β-Adrenergic and Muscarinic Receptor Activation. Frontiers in Physiology. 9: 510. PMID 29922167 DOI: 10.3389/Fphys.2018.00510  0.372
2018 Munch AS, Saljic A, Boddum K, Grunnet M, Hougaard C, Jespersen T. Pharmacological rescue of mutated K3.1 ion-channel linked to progressive myoclonus epilepsies. European Journal of Pharmacology. PMID 29894724 DOI: 10.1016/J.Ejphar.2018.06.015  0.452
2018 Boddum K, Saljic A, Jespersen T, Christensen AH. A Novel SCN5A Variant Associated with Abnormal Repolarization, Atrial Fibrillation, and Reversible Cardiomyopathy. Cardiology. 140: 8-13. PMID 29635243 DOI: 10.1159/000487475  0.359
2017 Andersen MN, Skibsbye L, Saljic A, Larsen MZ, Rasmussen HB, Jespersen T. Regulation of Kv1.4 potassium channels by PKC and AMPK kinases. Channels (Austin, Tex.). 0. PMID 29168928 DOI: 10.1080/19336950.2017.1405196  0.372
2017 Tommiska J, Känsäkoski J, Skibsbye L, Vaaralahti K, Liu X, Lodge EJ, Tang C, Yuan L, Fagerholm R, Kanters JK, Lahermo P, Kaunisto M, Keski-Filppula R, Vuoristo S, Pulli K, ... ... Jespersen T, et al. Two missense mutations in KCNQ1 cause pituitary hormone deficiency and maternally inherited gingival fibromatosis. Nature Communications. 8: 1289. PMID 29097701 DOI: 10.1038/S41467-017-01429-Z  0.54
2017 Carstensen H, Kjær L, Haugaard MM, Flethøj M, Hesselkilde EZ, Kanters JK, Pehrson S, Buhl R, Jespersen T. Antiarrhythmic Effects of Combining Dofetilide and Ranolazine in a Model of Acutely Induced Atrial Fibrillation in Horses. Journal of Cardiovascular Pharmacology. PMID 29068807 DOI: 10.1097/Fjc.0000000000000541  0.5
2017 Diness JG, Skibsbye L, Simó-Vicens R, Santos JL, Lundegaard P, Citerni C, Sauter DRP, Bomholtz SH, Svendsen JH, Olesen SP, Sørensen US, Jespersen T, Grunnet M, Bentzen BH. Termination of Vernakalant-Resistant Atrial Fibrillation by Inhibition of Small-Conductance Ca(2+)-Activated K(+) Channels in Pigs. Circulation. Arrhythmia and Electrophysiology. 10. PMID 29018164 DOI: 10.1161/Circep.117.005125  0.633
2017 von Schoubye NL, Frederiksen K, Kristiansen U, Petersen AV, Dalby NO, Grunnet M, Jensen HS, Jespersen T, Sohal VS, Perrier JF. The sodium channel activator Lu AE98134 normalizes the altered firing properties of fast spiking interneurons in Dlx5/6(+/-) mice. Neuroscience Letters. PMID 28987817 DOI: 10.1016/J.Neulet.2017.10.004  0.771
2017 Hundahl LA, Sattler SM, Skibsbye L, Diness JG, Tfelt-Hansen J, Jespersen T. Pharmacological blockade of small conductance Ca(2+)-activated K(+) channels by ICA reduces arrhythmic load in rats with acute myocardial infarction. Pflugers Archiv : European Journal of Physiology. 469: 739-750. PMID 28285409 DOI: 10.1007/S00424-017-1962-6  0.311
2017 Boddum K, Hougaard C, Xiao-Ying Lin J, von Schoubye NL, Jensen HS, Grunnet M, Jespersen T. Kv3.1/Kv3.2 channel positive modulators enable faster activating kinetics and increase firing frequency in fast-spiking GABAergic interneurons. Neuropharmacology. 118: 102-112. PMID 28242439 DOI: 10.1016/j.neuropharm.2017.02.024  0.806
2017 Hyltén-Cavallius L, Iepsen EW, Wewer Albrechtsen NJ, Svendstrup M, Lubberding AF, Hartmann B, Jespersen T, Linneberg A, Christiansen M, Vestergaard H, Pedersen O, Holst JJ, Kanters JK, Hansen T, Torekov SS. Patients With Long-QT Syndrome Caused by Impaired hERG-Encoded Kv11.1 Potassium Channel Have Exaggerated Endocrine Pancreatic and Incretin Function Associated With Reactive Hypoglycemia. Circulation. 135: 1705-1719. PMID 28235848 DOI: 10.1161/Circulationaha.116.024279  0.607
2017 Hoeker GS, Skarsfeldt MA, Jespersen T, Poelzing S. Electrophysiologic effects of the IK1 inhibitor PA-6 are modulated by extracellular potassium in isolated guinea pig hearts. Physiological Reports. 5. PMID 28087819 DOI: 10.14814/Phy2.13120  0.339
2016 Berchtold MW, Zacharias T, Kulej K, Wang K, Torggler R, Jespersen T, Chen JN, Larsen MR, La Cour JM. The Arrhythmogenic Calmodulin Mutation D129G Dysregulates Cell Growth, Calmodulin-dependent Kinase II Activity and Cardiac Function in Zebrafish. The Journal of Biological Chemistry. PMID 27815504 DOI: 10.1074/Jbc.M116.758680  0.328
2016 Skibsbye L, Jespersen T, Christ T, Maleckar MM, van den Brink J, Tavi P, Koivumäki JT. Refractoriness in human atria: Time and voltage dependence of sodium channel availability. Journal of Molecular and Cellular Cardiology. PMID 27773652 DOI: 10.1016/J.Yjmcc.2016.10.009  0.543
2016 Kirchhoff JE, Diness JG, Abildgaard L, Sheykhzade M, Grunnet M, Jespersen T. Antiarrhythmic effect of the Ca(2+)-activated K(+) (SK) channel inhibitor ICA combined with either amiodarone or dofetilide in an isolated heart model of atrial fibrillation. Pflugers Archiv : European Journal of Physiology. 468: 1853-1863. PMID 27722784 DOI: 10.1007/s00424-016-1883-9  0.346
2016 Skarsfeldt MA, Carstensen H, Skibsbye L, Tang C, Buhl R, Bentzen BH, Jespersen T. Pharmacological inhibition of IK1 by PA-6 in isolated rat hearts affects ventricular repolarization and refractoriness. Physiological Reports. 4. PMID 27117805 DOI: 10.14814/Phy2.12734  0.407
2016 van der Heyden MA, Jespersen T. Pharmacological exploration of the resting membrane potential reserve: Impact on atrial fibrillation. European Journal of Pharmacology. 771: 56-64. PMID 26601803 DOI: 10.1016/J.Ejphar.2015.11.026  0.5
2015 Kanters JK, Skibsbye L, Hedley PL, Dembic M, Liang B, Hagen CM, Eschen O, Grunnet M, Christiansen M, Jespersen T. Combined gating and trafficking defect in Kv11.1 manifests as a malignant long QT syndrome phenotype in a large Danish p.F29L founder family. Scandinavian Journal of Clinical and Laboratory Investigation. 1-11. PMID 26403377 DOI: 10.3109/00365513.2015.1091090  0.564
2015 Poulet C, Wettwer E, Grunnet M, Jespersen T, Fabritz L, Matschke K, Knaut M, Ravens U. Late Sodium Current in Human Atrial Cardiomyocytes from Patients in Sinus Rhythm and Atrial Fibrillation. Plos One. 10: e0131432. PMID 26121051 DOI: 10.1371/Journal.Pone.0131432  0.439
2015 Andersen MN, Skibsbye L, Tang C, Petersen F, MacAulay N, Rasmussen HB, Jespersen T. PKC and AMPK regulation of Kv1.5 potassium channels. Channels (Austin, Tex.). 9: 121-8. PMID 26043299 DOI: 10.1080/19336950.2015.1036205  0.536
2015 Tang C, Skibsbye L, Yuan L, Bentzen BH, Jespersen T. Biophysical characterization of inwardly rectifying potassium currents (IK1, IK, ACh, IK,Ca) using sinus rhythm or atrial fibrillation action potential waveforms. General Physiology and Biophysics. PMID 26001288 DOI: 10.4149/Gpb_2015015  0.344
2015 Diness JG, Kirchhoff JE, Sheykhzade M, Jespersen T, Grunnet M. Antiarrhythmic Effect of Either Negative Modulation or Blockade of Small Conductance Ca2+-activated K+ Channels on Ventricular Fibrillation in Guinea Pig Langendorff-perfused Heart. Journal of Cardiovascular Pharmacology. 66: 294-9. PMID 25978690 DOI: 10.1097/Fjc.0000000000000278  0.557
2015 Skibsbye L, Wang X, Axelsen LN, Bomholtz SH, Nielsen MS, Grunnet M, Bentzen BH, Jespersen T. Antiarrhythmic Mechanisms of SK Channel Inhibition in the Rat Atrium. Journal of Cardiovascular Pharmacology. PMID 25856531 DOI: 10.1097/Fjc.0000000000000259  0.525
2015 Taskin B, von Schoubye NL, Sheykhzade M, Bastlund JF, Grunnet M, Jespersen T. Biophysical characterization of KV3.1 potassium channel activating compounds. European Journal of Pharmacology. 758: 164-70. PMID 25845309 DOI: 10.1016/J.Ejphar.2015.03.061  0.796
2015 Jabbari J, Olesen MS, Yuan L, Nielsen JB, Liang B, Macri V, Christophersen IE, Nielsen N, Sajadieh A, Ellinor PT, Grunnet M, Haunsø S, Holst AG, Svendsen JH, Jespersen T. Common and rare variants in SCN10A modulate the risk of atrial fibrillation. Circulation. Cardiovascular Genetics. 8: 64-73. PMID 25691686 DOI: 10.1161/Circgenetics.113.000442  0.317
2015 Haugaard MM, Hesselkilde EZ, Pehrson S, Carstensen H, Flethøj M, Præstegaard KF, Sørensen US, Diness JG, Grunnet M, Buhl R, Jespersen T. Pharmacologic inhibition of small-conductance calcium-activated potassium (SK) channels by NS8593 reveals atrial antiarrhythmic potential in horses. Heart Rhythm. 12: 825-35. PMID 25542425 DOI: 10.1016/J.Hrthm.2014.12.028  0.47
2015 Kirchhoff JE, Diness JG, Sheykhzade M, Grunnet M, Jespersen T. Synergistic antiarrhythmic effect of combining inhibition of Ca²⁺-activated K⁺ (SK) channels and voltage-gated Na⁺ channels in an isolated heart model of atrial fibrillation. Heart Rhythm. 12: 409-18. PMID 25496982 DOI: 10.1016/J.Hrthm.2014.12.010  0.49
2014 Skibsbye L, Poulet C, Diness JG, Bentzen BH, Yuan L, Kappert U, Matschke K, Wettwer E, Ravens U, Grunnet M, Christ T, Jespersen T. Small-conductance calcium-activated potassium (SK) channels contribute to action potential repolarization in human atria. Cardiovascular Research. 103: 156-67. PMID 24817686 DOI: 10.1093/Cvr/Cvu121  0.5
2014 Kanters JK, Yuan L, Hedley PL, Stoevring B, Jons C, Bloch Thomsen PE, Grunnet M, Christiansen M, Jespersen T. Flecainide provocation reveals concealed brugada syndrome in a long QT syndrome family with a novel L1786Q mutation in SCN5A. Circulation Journal : Official Journal of the Japanese Circulation Society. 78: 1136-43. PMID 24599044 DOI: 10.1253/Circj.Cj-13-1167  0.535
2014 Yuan L, Koivumäki JT, Liang B, Lorentzen LG, Tang C, Andersen MN, Svendsen JH, Tfelt-Hansen J, Maleckar M, Schmitt N, Olesen MS, Jespersen T. Investigations of the Navβ1b sodium channel subunit in human ventricle; functional characterization of the H162P Brugada syndrome mutant. American Journal of Physiology. Heart and Circulatory Physiology. 306: H1204-12. PMID 24561865 DOI: 10.1152/Ajpheart.00405.2013  0.514
2014 Liang B, Nissen JD, Laursen M, Wang X, Skibsbye L, Hearing MC, Andersen MN, Rasmussen HB, Wickman K, Grunnet M, Olesen SP, Jespersen T. G-protein-coupled inward rectifier potassium current contributes to ventricular repolarization. Cardiovascular Research. 101: 175-84. PMID 24148898 DOI: 10.1093/Cvr/Cvt240  0.64
2014 Jensen CF, Skibsbye L, Bartels ED, Nielsen LB, Holstein-Rathlou N, Jespersen T, Axelsen LN, Nielsen MS. Normal Development Of Conduction Velocity In Rats Is Prevented By Fructose-Fat Feeding Heart Rhythm. 11: 2135. DOI: 10.1016/J.Hrthm.2014.09.029  0.312
2013 Andersen MN, Krzystanek K, Petersen F, Bomholtz SH, Olesen SP, Abriel H, Jespersen T, Rasmussen HB. A phosphoinositide 3-kinase (PI3K)-serum- and glucocorticoid-inducible kinase 1 (SGK1) pathway promotes Kv7.1 channel surface expression by inhibiting Nedd4-2 protein. The Journal of Biological Chemistry. 288: 36841-54. PMID 24214981 DOI: 10.1074/Jbc.M113.525931  0.618
2013 Hedley PL, Kanters JK, Dembic M, Jespersen T, Skibsbye L, Aidt FH, Eschen O, Graff C, Behr ER, Schlamowitz S, Corfield V, McKenna WJ, Christiansen M. The role of CAV3 in long-QT syndrome: clinical and functional assessment of a caveolin-3/Kv11.1 double heterozygote versus caveolin-3 single heterozygote. Circulation. Cardiovascular Genetics. 6: 452-61. PMID 24021552 DOI: 10.1161/Circgenetics.113.000137  0.556
2013 Wang X, Liang B, Skibsbye L, Olesen SP, Grunnet M, Jespersen T. GIRK channel activation via adenosine or muscarinic receptors has similar effects on rat atrial electrophysiology. Journal of Cardiovascular Pharmacology. 62: 192-8. PMID 23609329 DOI: 10.1097/Fjc.0B013E3182965221  0.683
2013 Jørgensen ST, Eriksen HN, Dausell J, Jespersen T, Lambert IH, Hoffmann EK. Double mutation at the putative protein kinase C phosphorylation sites Thr151 plus Thr323 in the mouse leukotrieneD4 receptor eliminates homologous desensitization. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 31: 366-78. PMID 23485744 DOI: 10.1159/000343374  0.354
2012 Olesen MS, Yuan L, Liang B, Holst AG, Nielsen N, Nielsen JB, Hedley PL, Christiansen M, Olesen SP, Haunsø S, Schmitt N, Jespersen T, Svendsen JH. High prevalence of long QT syndrome-associated SCN5A variants in patients with early-onset lone atrial fibrillation. Circulation. Cardiovascular Genetics. 5: 450-9. PMID 22685113 DOI: 10.1161/Circgenetics.111.962597  0.626
2012 Krzystanek K, Rasmussen HB, Grunnet M, Staub O, Olesen SP, Abriel H, Jespersen T. Deubiquitylating enzyme USP2 counteracts Nedd4-2-mediated downregulation of KCNQ1 potassium channels. Heart Rhythm : the Official Journal of the Heart Rhythm Society. 9: 440-8. PMID 22024150 DOI: 10.1016/J.Hrthm.2011.10.026  0.706
2012 Nissen JD, Thomsen MB, Bentzen BH, Diness JG, Diness TG, Jespersen T, Grunnet M. Attenuated ventricular β-adrenergic response and reduced repolarization reserve in a rabbit model of chronic heart failure. Journal of Cardiovascular Pharmacology. 59: 142-50. PMID 21992969 DOI: 10.1097/Fjc.0B013E318238727A  0.324
2012 Andersen MN, Krzystanek K, Jespersen T, Olesen SP, Rasmussen HB. AMP-activated protein kinase downregulates Kv7.1 cell surface expression. Traffic (Copenhagen, Denmark). 13: 143-56. PMID 21957902 DOI: 10.1111/J.1600-0854.2011.01295.X  0.649
2011 Tfelt-Hansen J, Winkel BG, Grunnet M, Jespersen T. Cardiac channelopathies and sudden infant death syndrome. Cardiology. 119: 21-33. PMID 21778721 DOI: 10.1159/000329047  0.463
2011 Olesen MS, Jensen NF, Holst AG, Nielsen JB, Tfelt-Hansen J, Jespersen T, Sajadieh A, Haunsø S, Lund JT, Calloe K, Schmitt N, Svendsen JH. A novel nonsense variant in Nav1.5 cofactor MOG1 eliminates its sodium current increasing effect and may increase the risk of arrhythmias. The Canadian Journal of Cardiology. 27: 523.e17-23. PMID 21621375 DOI: 10.1016/J.Cjca.2011.01.003  0.48
2011 Laursen M, Grunnet M, Olesen SP, Jespersen T, Mow T. Keeping the rhythm -- pro-arrhythmic investigations in isolated Göttingen minipig hearts. Journal of Pharmacological and Toxicological Methods. 64: 134-44. PMID 21616157 DOI: 10.1016/J.Vascn.2011.05.001  0.588
2011 Jespersen T. Regulation and physiological function of Na(v) 1.5 and KCNQ1 channels. Acta Physiologica (Oxford, England). 1-26. PMID 21569218 DOI: 10.1111/J.1748-1716.2011.02300.X  0.472
2011 Diness JG, Skibsbye L, Jespersen T, Bartels ED, Sørensen US, Hansen RS, Grunnet M. Effects on atrial fibrillation in aged hypertensive rats by Ca(2+)-activated K(+) channel inhibition. Hypertension. 57: 1129-35. PMID 21502564 DOI: 10.1161/Hypertensionaha.111.170613  0.432
2011 Calloe K, Nof E, Jespersen T, Di Diego JM, Chlus N, Olesen SP, Antzelevitch C, Cordeiro JM. Comparison of the effects of a transient outward potassium channel activator on currents recorded from atrial and ventricular cardiomyocytes. Journal of Cardiovascular Electrophysiology. 22: 1057-66. PMID 21457383 DOI: 10.1111/J.1540-8167.2011.02053.X  0.676
2011 Olesen MS, Jabbari J, Holst AG, Nielsen JB, Steinbrüchel DA, Jespersen T, Haunsø S, Svendsen JH. Screening of KCNN3 in patients with early-onset lone atrial fibrillation. Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups On Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology. 13: 963-7. PMID 21398315 DOI: 10.1093/Europace/Eur007  0.355
2011 Olesen MS, Jespersen T, Nielsen JB, Liang B, Møller DV, Hedley P, Christiansen M, Varró A, Olesen SP, Haunsø S, Schmitt N, Svendsen JH. Mutations in sodium channel β-subunit SCN3B are associated with early-onset lone atrial fibrillation. Cardiovascular Research. 89: 786-93. PMID 21051419 DOI: 10.1093/Cvr/Cvq348  0.645
2011 Laursen M, Olesen SP, Grunnet M, Mow T, Jespersen T. Characterization of cardiac repolarization in the Göttingen minipig. Journal of Pharmacological and Toxicological Methods. 63: 186-95. PMID 20951813 DOI: 10.1016/J.Vascn.2010.10.001  0.615
2011 Liang B, Yang Y, Yang Y, Grunnet M, Olesen S, Chen Y, Jespersen T. Reduction in cardiac Kir3.4 channel expression causes congenital long-QT syndrome—a functional role of GIRK currents in ventricular repolarization Journal of Electrocardiology. 44: e15. DOI: 10.1016/J.Hrthm.2009.09.031  0.701
2010 Diness JG, Sørensen US, Nissen JD, Al-Shahib B, Jespersen T, Grunnet M, Hansen RS. Inhibition of small-conductance Ca2+-activated K+ channels terminates and protects against atrial fibrillation. Circulation. Arrhythmia and Electrophysiology. 3: 380-90. PMID 20562443 DOI: 10.1161/Circep.110.957407  0.504
2010 Yang Y, Yang Y, Liang B, Liu J, Li J, Grunnet M, Olesen SP, Rasmussen HB, Ellinor PT, Gao L, Lin X, Li L, Wang L, Xiao J, Liu Y, ... ... Jespersen T, et al. Identification of a Kir3.4 mutation in congenital long QT syndrome. American Journal of Human Genetics. 86: 872-80. PMID 20560207 DOI: 10.1016/J.Ajhg.2010.04.017  0.624
2010 Holst AG, Liang B, Jespersen T, Bundgaard H, Haunso S, Svendsen JH, Tfelt-Hansen J. Sick sinus syndrome, progressive cardiac conduction disease, atrial flutter and ventricular tachycardia caused by a novel SCN5A mutation. Cardiology. 115: 311-6. PMID 20395683 DOI: 10.1159/000312747  0.376
2010 Tfelt-Hansen J, Winkel BG, Grunnet M, Jespersen T. Inherited cardiac diseases caused by mutations in the Nav1.5 sodium channel. Journal of Cardiovascular Electrophysiology. 21: 107-15. PMID 19845816 DOI: 10.1111/J.1540-8167.2009.01633.X  0.468
2010 Calloe K, Soltysinska E, Jespersen T, Lundby A, Antzelevitch C, Olesen SP, Cordeiro JM. Differential effects of the transient outward K(+) current activator NS5806 in the canine left ventricle. Journal of Molecular and Cellular Cardiology. 48: 191-200. PMID 19632239 DOI: 10.1016/J.Yjmcc.2009.07.017  0.614
2010 Krzystanek K, Grunnet M, Olesen SP, Abriel H, Jespersen T. Regulation of the Cardiac Iks Channel Complex by Ubiquitylation and De-Ubiquitylation Biophysical Journal. 98: 534a. DOI: 10.1016/J.Bpj.2009.12.2897  0.722
2010 Calloe K, Chlus N, Nof E, Jespersen T, Olesen S, Antzelevitch C, Cordeiro J. Comparison of the Effects of the Transient Outward Potassium Channel Activator NS5806 on Canine Atrial and Ventricular Cardiomyocytes Biophysical Journal. 98: 334a. DOI: 10.1016/J.Bpj.2009.12.1813  0.647
2009 Holst AG, Calloe K, Jespersen T, Cedergreen P, Winkel BG, Jensen HK, Leren TP, Haunso S, Svendsen JH, Tfelt-Hansen J. A Novel SCN5A Mutation in a Patient with Coexistence of Brugada Syndrome Traits and Ischaemic Heart Disease. Case Reports in Medicine. 2009: 963645. PMID 19829766 DOI: 10.1155/2009/963645  0.416
2009 Soltysinska E, Olesen SP, Christ T, Wettwer E, Varró A, Grunnet M, Jespersen T. Transmural expression of ion channels and transporters in human nondiseased and end-stage failing hearts. PflüGers Archiv : European Journal of Physiology. 459: 11-23. PMID 19768467 DOI: 10.1007/S00424-009-0718-3  0.647
2009 Nissen JD, Diness JG, Diness TG, Hansen RS, Grunnet M, Jespersen T. Pharmacologically induced long QT type 2 can be rescued by activation of IKs with benzodiazepine R-L3 in isolated guinea pig cardiomyocytes. Journal of Cardiovascular Pharmacology. 54: 169-77. PMID 19568177 DOI: 10.1097/Fjc.0B013E3181Af6Db3  0.33
2009 Tfelt-Hansen J, Olesen SP, Svendsen JH, Jespersen T. [Inherited cardiac diseases caused by Nav1.5 sodium channel mutations]. Ugeskrift For Laeger. 171: 1261-5. PMID 19416615  0.648
2009 Tfelt-Hansen J, Jespersen T, Hofman-Bang J, Rasmussen HB, Cedergreen P, Skovby F, Abriel H, Svendsen JH, Olesen SP, Christiansen M, Haunso S. Ventricular tachycardia in a Brugada syndrome patient caused by a novel deletion in SCN5A. The Canadian Journal of Cardiology. 25: 156-60. PMID 19279983 DOI: 10.1016/S0828-282X(09)70043-1  0.601
2009 Diness JG, Hansen RS, Nissen JD, Jespersen T, Grunnet M. Antiarrhythmic effect of IKr activation in a cellular model of LQT3. Heart Rhythm : the Official Journal of the Heart Rhythm Society. 6: 100-6. PMID 19121808 DOI: 10.1016/J.Hrthm.2008.10.020  0.453
2009 Bentzen BH, Osadchii O, Jespersen T, Hansen RS, Olesen SP, Grunnet M. Activation of big conductance Ca(2+)-activated K (+) channels (BK) protects the heart against ischemia-reperfusion injury. PflüGers Archiv : European Journal of Physiology. 457: 979-88. PMID 18762970 DOI: 10.1007/S00424-008-0583-5  0.709
2009 Liang B, Yang Y, Yang Y, Liu J, Grunnet M, Olesen S, Chen Y, Jespersen T. Reduction in Cardiac Kir3.4 Channel Expression Causes Congenital Long QT Syndrome: A Functional Role of Girk Currents in Ventricular Repolarization Heart Rhythm. 6: 1685-1686. DOI: 10.1016/J.HRTHM.2009.09.031  0.661
2009 Lundby A, Jespersen T, Schmitt N, Grunnet M, Olesen S, Cordeiro JM, Calloe K. The Effect Of The Ito Activator NS5806 On Cloned Kv4.3 Channels Is Dependent On The Accessory Protein KChIP2 Biophysical Journal. 96: 659a. DOI: 10.1016/J.Bpj.2008.12.3480  0.716
2008 Larsen AP, Olesen SP, Grunnet M, Jespersen T. Characterization of hERG1a and hERG1b potassium channels-a possible role for hERG1b in the I (Kr) current. PflüGers Archiv : European Journal of Physiology. 456: 1137-48. PMID 18504605 DOI: 10.1007/S00424-008-0476-7  0.715
2008 Petitprez S, Jespersen T, Pruvot E, Keller DI, Corbaz C, Schläpfer J, Abriel H, Kucera JP. Analyses of a novel SCN5A mutation (C1850S): conduction vs. repolarization disorder hypotheses in the Brugada syndrome. Cardiovascular Research. 78: 494-504. PMID 18252757 DOI: 10.1093/Cvr/Cvn023  0.403
2007 Kranjcec D, Bergovec M, Rougier JS, Raguz M, Pavlovic S, Jespersen T, Castella V, Keller DI, Abriel H. Brugada syndrome unmasked by accidental inhalation of gasoline vapors. Pacing and Clinical Electrophysiology : Pace. 30: 1294-8. PMID 17897138 DOI: 10.1111/J.1540-8159.2007.00857.X  0.367
2007 Jespersen T, Membrez M, Nicolas CS, Pitard B, Staub O, Olesen SP, Baró I, Abriel H. The KCNQ1 potassium channel is down-regulated by ubiquitylating enzymes of the Nedd4/Nedd4-like family. Cardiovascular Research. 74: 64-74. PMID 17289006 DOI: 10.1016/J.Cardiores.2007.01.008  0.718
2007 Larsen AP, Jespersen T, Grunnet M, Olesen SP. Electrophysiological characterization of hERG1a and hERG1b Homo- and heteromeric channels Journal of Molecular and Cellular Cardiology. 42: S17-S18. DOI: 10.1016/J.Yjmcc.2007.03.050  0.521
2006 Jespersen T, Gavillet B, van Bemmelen MX, Cordonier S, Thomas MA, Staub O, Abriel H. Cardiac sodium channel Na(v)1.5 interacts with and is regulated by the protein tyrosine phosphatase PTPH1. Biochemical and Biophysical Research Communications. 348: 1455-62. PMID 16930557 DOI: 10.1016/J.Bbrc.2006.08.014  0.45
2006 Peitersen T, Hougaard C, Jespersen T, Jorgensen NK, Olesen SP, Grunnet M. Subtype-specific, bi-component inhibition of SK channels by low internal pH. Biochemical and Biophysical Research Communications. 343: 943-9. PMID 16566895 DOI: 10.1016/J.Bbrc.2006.03.026  0.613
2006 Jespersen T, Grunnet M, Rasmussen HB, Jørgensen NB, Jensen HS, Angelo K, Olesen SP, Klaerke DA. The corticosteroid hormone induced factor: a new modulator of KCNQ1 channels? Biochemical and Biophysical Research Communications. 341: 979-88. PMID 16476578 DOI: 10.1016/J.Bbrc.2006.01.046  0.829
2005 Jespersen T, Grunnet M, Olesen SP. The KCNQ1 potassium channel: from gene to physiological function. Physiology (Bethesda, Md.). 20: 408-16. PMID 16287990 DOI: 10.1152/Physiol.00031.2005  0.713
2005 Jensen HS, Callø K, Jespersen T, Jensen BS, Olesen SP. The KCNQ5 potassium channel from mouse: a broadly expressed M-current like potassium channel modulated by zinc, pH, and volume changes. Brain Research. Molecular Brain Research. 139: 52-62. PMID 15963599 DOI: 10.1016/J.Molbrainres.2005.05.007  0.719
2005 Grunnet M, Olesen SP, Klaerke DA, Jespersen T. hKCNE4 inhibits the hKCNQ1 potassium current without affecting the activation kinetics. Biochemical and Biophysical Research Communications. 328: 1146-53. PMID 15707997 DOI: 10.1016/J.Bbrc.2005.01.071  0.652
2005 Rougier JS, van Bemmelen MX, Bruce MC, Jespersen T, Gavillet B, Apothéloz F, Cordonier S, Staub O, Rotin D, Abriel H. Molecular determinants of voltage-gated sodium channel regulation by the Nedd4/Nedd4-like proteins. American Journal of Physiology. Cell Physiology. 288: C692-701. PMID 15548568 DOI: 10.1152/Ajpcell.00460.2004  0.396
2004 Grunnet M, Jespersen T, Perrier JF. 5-HT1A receptors modulate small-conductance Ca2+-activated K+ channels. Journal of Neuroscience Research. 78: 845-54. PMID 15521063 DOI: 10.1002/Jnr.20318  0.699
2004 Jespersen T, Rasmussen HB, Grunnet M, Jensen HS, Angelo K, Dupuis DS, Vogel LK, Jorgensen NK, Klaerke DA, Olesen SP. Basolateral localisation of KCNQ1 potassium channels in MDCK cells: molecular identification of an N-terminal targeting motif. Journal of Cell Science. 117: 4517-26. PMID 15316073 DOI: 10.1242/Jcs.01318  0.824
2004 Hofman-Bang J, Jespersen T, Grunnet M, Larsen LA, Andersen PS, Kanters JK, Kjeldsen K, Christiansen M. Does KCNE5 play a role in long QT syndrome? Clinica Chimica Acta; International Journal of Clinical Chemistry. 345: 49-53. PMID 15193977 DOI: 10.1016/J.Cccn.2004.02.033  0.649
2004 Dunø M, Colding-Jørgensen E, Grunnet M, Jespersen T, Vissing J, Schwartz M. Difference in allelic expression of the CLCN1 gene and the possible influence on the myotonia congenita phenotype. European Journal of Human Genetics : Ejhg. 12: 738-43. PMID 15162127 DOI: 10.1038/Sj.Ejhg.5201218  0.336
2003 Grunnet M, Jespersen T, Colding-Jørgensen E, Schwartz M, Klaerke DA, Vissing J, Olesen SP, Dunø M. Characterization of two new dominant ClC-1 channel mutations associated with myotonia. Muscle & Nerve. 28: 722-32. PMID 14639587 DOI: 10.1002/Mus.10501  0.69
2003 Grunnet M, Rasmussen HB, Hay-Schmidt A, Rosenstierne M, Klaerke DA, Olesen SP, Jespersen T. KCNE4 is an inhibitory subunit to Kv1.1 and Kv1.3 potassium channels. Biophysical Journal. 85: 1525-37. PMID 12944270 DOI: 10.1016/S0006-3495(03)74585-8  0.715
2003 Grunnet M, Jespersen T, MacAulay N, Jørgensen NK, Schmitt N, Pongs O, Olesen SP, Klaerke DA. KCNQ1 channels sense small changes in cell volume. The Journal of Physiology. 549: 419-27. PMID 12702742 DOI: 10.1113/Jphysiol.2003.038455  0.697
2003 Schrøder RL, Jespersen T, Christophersen P, Strøbæk D, Jensen BS, Olesen S. Corrigendum to “KCNQ4 channel activation by BMS-204352 and retigabine” Neuropharmacology. 44: 553. DOI: 10.1016/S0028-3908(03)00038-8  0.69
2003 Dupuis DS, Schrøder RL, Jespersen T, Christensen JK, Christophersen P, Jensen BS, Olesen SP. Corrigendum to “Activation of KCNQ5 channels stably expressed in HEK293 cells by BMS-204352” [Eur. J. Pharmacol. 437 (2002) 129–137] European Journal of Pharmacology. 465: 201. DOI: 10.1016/S0014-2999(03)01436-5  0.482
2002 Angelo K, Jespersen T, Grunnet M, Nielsen MS, Klaerke DA, Olesen SP. KCNE5 induces time- and voltage-dependent modulation of the KCNQ1 current. Biophysical Journal. 83: 1997-2006. PMID 12324418 DOI: 10.1016/S0006-3495(02)73961-1  0.828
2002 Grunnet M, Jespersen T, Rasmussen HB, Ljungstrøm T, Jorgensen NK, Olesen SP, Klaerke DA. KCNE4 is an inhibitory subunit to the KCNQ1 channel. The Journal of Physiology. 542: 119-30. PMID 12096056 DOI: 10.1113/Jphysiol.2002.017301  0.709
2002 Jespersen T, Grunnet M, Angelo K, Klaerke DA, Olesen SP. Dual-function vector for protein expression in both mammalian cells and Xenopus laevis oocytes. Biotechniques. 32: 536-8, 540. PMID 11911656 DOI: 10.2144/02323St05  0.779
2002 Dupuis DS, Schrøder RL, Jespersen T, Christensen JK, Christophersen P, Jensen BS, Olesen SP. Activation of KCNQ5 channels stably expressed in HEK293 cells by BMS-204352. European Journal of Pharmacology. 437: 129-37. PMID 11890900 DOI: 10.1016/S0014-2999(02)01287-6  0.554
2001 Schrøder RL, Jespersen T, Christophersen P, Strøbaek D, Jensen BS, Olesen SP. KCNQ4 channel activation by BMS-204352 and retigabine. Neuropharmacology. 40: 888-98. PMID 11378159 DOI: 10.1016/S0028-3908(01)00029-6  0.719
2001 Grunnet M, Jespersen T, Angelo K, Frøkjaer-Jensen C, Klaerke DA, Olesen SP, Jensen BS. Pharmacological modulation of SK3 channels. Neuropharmacology. 40: 879-87. PMID 11378158 DOI: 10.1016/S0028-3908(01)00028-4  0.83
2001 Korolkova YV, Kozlov SA, Lipkin AV, Pluzhnikov KA, Hadley JK, Filippov AK, Brown DA, Angelo K, Strøbaek D, Jespersen T, Olesen SP, Jensen BS, Grishin EV. An ERG channel inhibitor from the scorpion Buthus eupeus. The Journal of Biological Chemistry. 276: 9868-76. PMID 11136720 DOI: 10.1074/Jbc.M005973200  0.812
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