Kelly R Miller - Related publications

Affiliations: 
2016- NanoString  
Area:
Neuroscience, microglia, neurodegenerative disease
NOTE: We are testing a new system for identifying relevant work based on semantic analysis that identifies similarities between recently published papers and the current author's publications. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches.
50 most relevant papers in past 60 days:
Year Citation  Score
2020 Holloway OG, King AE, Ziebell JM. Microglia Demonstrate Local Mixed Inflammation and a Defined Morphological Shift in an APP/PS1 Mouse Model. Journal of Alzheimer's Disease : Jad. PMID 32894243 DOI: 10.3233/JAD-200098   
2020 Lau SF, Cao H, Fu AKY, Ip NY. Single-nucleus transcriptome analysis reveals dysregulation of angiogenic endothelial cells and neuroprotective glia in Alzheimer's disease. Proceedings of the National Academy of Sciences of the United States of America. PMID 32989152 DOI: 10.1073/pnas.2008762117   
2020 von Saucken VE, Jay TR, Landreth GE. The effect of amyloid on microglia-neuron interactions before plaque onset occurs independently of TREM2 in a mouse model of Alzheimer's disease. Neurobiology of Disease. 105072. PMID 32890775 DOI: 10.1016/j.nbd.2020.105072   
2020 Zhang Y, Zhao Y, Zhang J, Yang G. Mechanisms of NLRP3 Inflammasome Activation: Its Role in the Treatment of Alzheimer's Disease. Neurochemical Research. PMID 32929691 DOI: 10.1007/s11064-020-03121-z   
2020 Ochi S, Iga JI, Funahashi Y, Yoshino Y, Yamazaki K, Kumon H, Mori H, Ozaki Y, Mori T, Ueno SI. Identifying Blood Transcriptome Biomarkers of Alzheimer's Disease Using Transgenic Mice. Molecular Neurobiology. PMID 32816243 DOI: 10.1007/s12035-020-02058-2   
2020 Park KHJ, Barrett T. Gliosis Precedes Amyloid-β Deposition and Pathological Tau Accumulation in the Neuronal Cell Cycle Re-Entry Mouse Model of Alzheimer's Disease. Journal of Alzheimer's Disease Reports. 4: 243-253. PMID 32904753 DOI: 10.3233/ADR-200170   
2020 Lee HJ, Woo H, Lee HE, Jeon H, Ryu KY, Nam JH, Jeon SG, Park H, Lee JS, Han KM, Lee SM, Kim J, Kang RJ, Lee YH, Kim JI, et al. The novel DYRK1A inhibitor KVN93 regulates cognitive function, amyloid-beta pathology, and neuroinflammation. Free Radical Biology & Medicine. PMID 32896600 DOI: 10.1016/j.freeradbiomed.2020.08.030   
2020 Das R, Chinnathambi S. Actin-mediated microglial chemotaxis via G-protein coupled Purinergic receptor in Alzheimer's disease. Neuroscience. PMID 32941933 DOI: 10.1016/j.neuroscience.2020.09.024   
2020 Dhanwani R, Pham J, Premlal ALR, Frazier A, Kumar A, Pero ME, Bartolini F, Dutra JR, Marder KS, Peters B, Sulzer D, Sette A, Lindestam Arlehamn CS. T Cell Responses to Neural Autoantigens Are Similar in Alzheimer's Disease Patients and Age-Matched Healthy Controls. Frontiers in Neuroscience. 14: 874. PMID 32982670 DOI: 10.3389/fnins.2020.00874   
2020 Huang L, McClatchy DB, Maher P, Liang Z, Diedrich JK, Soriano-Castell D, Goldberg J, Shokhirev M, Yates JR, Schubert D, Currais A. Intracellular amyloid toxicity induces oxytosis/ferroptosis regulated cell death. Cell Death & Disease. 11: 828. PMID 33024077 DOI: 10.1038/s41419-020-03020-9   
2020 Doustar J, Rentsendorj A, Torbati T, Regis GC, Fuchs DT, Sheyn J, Mirzaei N, Graham SL, Shah PK, Mastali M, Van Eyk JE, Black KL, Gupta VK, Mirzaei M, Koronyo Y, et al. Parallels between retinal and brain pathology and response to immunotherapy in old, late-stage Alzheimer's disease mouse models. Aging Cell. e13246. PMID 33090673 DOI: 10.1111/acel.13246   
2020 Qu X, Guan P, Han L, Wang Z, Huang X. Levistolide A Attenuates Alzheimer's Pathology Through Activation of the PPARγ Pathway. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. PMID 33034847 DOI: 10.1007/s13311-020-00943-1   
2020 Lewcock JW, Schlepckow K, Di Paolo G, Tahirovic S, Monroe KM, Haass C. Emerging Microglia Biology Defines Novel Therapeutic Approaches for Alzheimer's Disease. Neuron. PMID 33096024 DOI: 10.1016/j.neuron.2020.09.029   
2020 Carmona-Abellan M, Martinez-Valbuena I, Marcilla I, DiCaudo C, Gil I, Nuñez J, Luquin MR. Microglia is associated with p-Tau aggregates in the olfactory bulb of patients with neurodegenerative diseases. Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology. PMID 32816165 DOI: 10.1007/s10072-020-04686-x   
2020 Chiasseu M, Fesharaki A, Saito T, Saido TC, Strittmatter SM. Gene-environment interaction promotes Alzheimer's risk as revealed by synergy of repeated mild traumatic brain injury and mouse App knock-in. Neurobiology of Disease. 145: 105059. PMID 32858147 DOI: 10.1016/j.nbd.2020.105059   
2020 Garcia-Leon JA, Caceres-Palomo L, Sanchez-Mejias E, Mejias-Ortega M, Nuñez-Diaz C, Fernandez-Valenzuela JJ, Sanchez-Varo R, Davila JC, Vitorica J, Gutierrez A. Human Pluripotent Stem Cell-Derived Neural Cells as a Relevant Platform for Drug Screening in Alzheimer's Disease. International Journal of Molecular Sciences. 21. PMID 32962164 DOI: 10.3390/ijms21186867   
2020 Du Y, Luo M, Du Y, Xu M, Yao Q, Wang K, He G. Liquiritigenin Decreases Aβ Levels and Ameliorates Cognitive Decline by Regulating Microglia M1/M2 Transformation in AD Mice. Neurotoxicity Research. PMID 32990912 DOI: 10.1007/s12640-020-00284-z   
2020 Takalo M, Wittrahm R, Wefers B, Parhizkar S, Jokivarsi K, Kuulasmaa T, Mäkinen P, Martiskainen H, Wurst W, Xiang X, Marttinen M, Poutiainen P, Haapasalo A, Hiltunen M, Haass C. The Alzheimer's disease-associated protective Plcγ2-P522R variant promotes immune functions. Molecular Neurodegeneration. 15: 52. PMID 32917267 DOI: 10.1186/s13024-020-00402-7   
2020 Li N, Stewart T, Sheng L, Shi M, Cilento EM, Wu Y, Hong JS, Zhang J. Immunoregulation of microglial polarization: an unrecognized physiological function of α-synuclein. Journal of Neuroinflammation. 17: 272. PMID 32943057 DOI: 10.1186/s12974-020-01940-z   
2020 Kempuraj D, Thangavel R, Kempuraj DD, Ahmed ME, Selvakumar GP, Raikwar SP, Zaheer SA, Iyer SS, Govindarajan R, Chandrasekaran PN, Zaheer A. Neuroprotective effects of flavone luteolin in neuroinflammation and neurotrauma. Biofactors (Oxford, England). PMID 33098588 DOI: 10.1002/biof.1687   
2020 Ray WJ, Buggia-Prevot V. Novel Targets for Alzheimer's Disease: A View Beyond Amyloid. Annual Review of Medicine. PMID 32867590 DOI: 10.1146/annurev-med-052919-120219   
2020 Franzmeier N, Suárez-Calvet M, Frontzkowski L, Moore A, Hohman TJ, Morenas-Rodriguez E, Nuscher B, Shaw L, Trojanowski JQ, Dichgans M, Kleinberger G, Haass C, Ewers M, . Higher CSF sTREM2 attenuates ApoE4-related risk for cognitive decline and neurodegeneration. Molecular Neurodegeneration. 15: 57. PMID 33032659 DOI: 10.1186/s13024-020-00407-2   
2020 Han F, Bi J, Qiao L, Arancio O. Stem Cell Therapy for Alzheimer's Disease. Advances in Experimental Medicine and Biology. 1266: 39-55. PMID 33105494 DOI: 10.1007/978-981-15-4370-8_4   
2020 Zhao L, Li Z, Vong JSL, Chen X, Lai HM, Yan LYC, Huang J, Sy SKH, Tian X, Huang Y, Chan HYE, So HC, Ng WL, Tang Y, Lin WJ, et al. Pharmacologically reversible zonation-dependent endothelial cell transcriptomic changes with neurodegenerative disease associations in the aged brain. Nature Communications. 11: 4413. PMID 32887883 DOI: 10.1038/s41467-020-18249-3   
2020 Stoyanov S, Sun W, Düsedau HP, Cangalaya C, Choi I, Mirzapourdelavar H, Baidoe-Ansah D, Kaushik R, Neumann J, Dunay IR, Dityatev A. Attenuation of the extracellular matrix restores microglial activity during the early stage of amyloidosis. Glia. PMID 32865286 DOI: 10.1002/glia.23894   
2020 Lee J, Kong E, Hong S, Moon J, Kim P. longitudinal visualization of the brain neuroinflammatory response at the cellular level in LysM-GFP mice induced by 3-nitropropionic acid. Biomedical Optics Express. 11: 4835-4847. PMID 32923081 DOI: 10.1364/BOE.393690   
2020 Cranston AL, Wysocka A, Steczkowska M, Zadrożny M, Palasz E, Harrington CR, Theuring F, Wischik CM, Riedel G, Niewiadomska G. Cholinergic and inflammatory phenotypes in transgenic tau mouse models of Alzheimer's disease and frontotemporal lobar degeneration. Brain Communications. 2: fcaa033. PMID 32954291 DOI: 10.1093/braincomms/fcaa033   
2020 Cuddy LK, Prokopenko D, Cunningham EP, Brimberry R, Song P, Kirchner R, Chapman BA, Hofmann O, Hide W, Procissi D, Hanania T, Leiser SC, Tanzi RE, Vassar R. Aβ-accelerated neurodegeneration caused by Alzheimer's-associated variant R1279Q is rescued by angiotensin system inhibition in mice. Science Translational Medicine. 12. PMID 32998969 DOI: 10.1126/scitranslmed.aaz2541   
2020 Momtazmanesh S, Perry G, Rezaei N. Toll-like receptors in Alzheimer's disease. Journal of Neuroimmunology. 348: 577362. PMID 32858428 DOI: 10.1016/j.jneuroim.2020.577362   
2020 Ruganzu JB, Zheng Q, Wu X, He Y, Peng X, Jin H, Zhou J, Ma R, Ji S, Ma Y, Qian Y, Wang Y, Yang W. TREM2 overexpression rescues cognitive deficits in APP/PS1 transgenic mice by reducing neuroinflammation via the JAK/STAT/SOCS signaling pathway. Experimental Neurology. 113506. PMID 33065077 DOI: 10.1016/j.expneurol.2020.113506   
2020 Cecarini V, Bonfili L, Gogoi O, Lawrence S, Venanzi FM, Azevedo V, Mancha-Agresti P, Drumond MM, Rossi G, Berardi S, Galosi L, Cuccioloni M, Angeletti M, Suchodolski JS, Pilla R, et al. Neuroprotective effects of p62(SQSTM1)-engineered lactic acid bacteria in Alzheimer's disease: a pre-clinical study. Aging. 12. PMID 32855357 DOI: 10.18632/aging.103900   
2020 Gu H, Territo PR, Persohn SA, Bedwell AA, Eldridge K, Speedy R, Chen Z, Zheng W, Du Y. Evaluation of chronic lead effects in the blood brain barrier system by DCE-CT. Journal of Trace Elements in Medicine and Biology : Organ of the Society For Minerals and Trace Elements (Gms). 62: 126648. PMID 32980769 DOI: 10.1016/j.jtemb.2020.126648   
2020 Sun Y, Huang J, Chen Y, Shang H, Zhang W, Yu J, He L, Xing C, Zhuang C. Direct inhibition of Keap1-Nrf2 Protein-Protein interaction as a potential therapeutic strategy for Alzheimer's disease. Bioorganic Chemistry. 103: 104172. PMID 32890991 DOI: 10.1016/j.bioorg.2020.104172   
2020 Nishi T, Kondo S, Miyamoto M, Watanabe S, Hasegawa S, Kondo S, Yano J, Watanabe E, Ishi T, Yoshikawa M, Ando HK, Farnaby W, Fujimoto S, Sunahara E, Ohori M, et al. Soticlestat, a novel cholesterol 24-hydroxylase inhibitor shows a therapeutic potential for neural hyperexcitation in mice. Scientific Reports. 10: 17081. PMID 33051477 DOI: 10.1038/s41598-020-74036-6   
2020 Simpson DSA, Oliver PL. ROS Generation in Microglia: Understanding Oxidative Stress and Inflammation in Neurodegenerative Disease. Antioxidants (Basel, Switzerland). 9. PMID 32823544 DOI: 10.3390/antiox9080743   
2020 Feng W, Zhang Y, Wang Z, Xu H, Wu T, Marshall C, Gao J, Xiao M. Microglia prevent beta-amyloid plaque formation in the early stage of an Alzheimer's disease mouse model with suppression of glymphatic clearance. Alzheimer's Research & Therapy. 12: 125. PMID 33008458 DOI: 10.1186/s13195-020-00688-1   
2020 Noe CR, Noe-Letschnig M, Handschuh P, Noe CA, Lanzenberger R. Dysfunction of the Blood-Brain Barrier-A Key Step in Neurodegeneration and Dementia. Frontiers in Aging Neuroscience. 12: 185. PMID 32848697 DOI: 10.3389/fnagi.2020.00185   
2020 Flores J, Noël A, Foveau B, Beauchet O, LeBlanc AC. Pre-symptomatic Caspase-1 inhibitor delays cognitive decline in a mouse model of Alzheimer disease and aging. Nature Communications. 11: 4571. PMID 32917871 DOI: 10.1038/s41467-020-18405-9   
2020 Marschall P, Wei R, Segaud J, Yao W, Hener P, German BF, Meyer P, Hugel C, Da Silva GA, Braun R, Kaplan DH, Li M. Dual function of Langerhans cells in skin TSLP-promoted Tfh cell differentiation in mouse atopic dermatitis. The Journal of Allergy and Clinical Immunology. PMID 33068561 DOI: 10.1016/j.jaci.2020.10.006   
2020 Propson NE, Roy ER, Litvinchuk A, Köhl J, Zheng H. Endothelial C3a receptor mediates vascular inflammation and BBB permeability during aging. The Journal of Clinical Investigation. PMID 32990682 DOI: 10.1172/JCI140966   
2020 Hao F, Feng Y. Cannabidiol (CBD) enhanced the hippocampal immune response and autophagy of APP/PS1 Alzheimer's mice uncovered by RNA-seq. Life Sciences. 118624. PMID 33096116 DOI: 10.1016/j.lfs.2020.118624   
2020 Stevenson R, Samokhina E, Rossetti I, Morley JW, Buskila Y. Neuromodulation of Glial Function During Neurodegeneration. Frontiers in Cellular Neuroscience. 14: 278. PMID 32973460 DOI: 10.3389/fncel.2020.00278   
2020 Dong CM, Guo AS, To A, Chan KWY, Chow ASF, Bian L, Leong ATL, Wu EX. Early Detection of Amyloid β Pathology in Alzheimer's Disease by Molecular MRI. Annual International Conference of the Ieee Engineering in Medicine and Biology Society. Ieee Engineering in Medicine and Biology Society. Annual International Conference. 2020: 1100-1103. PMID 33018178 DOI: 10.1109/EMBC44109.2020.9176013   
2020 Kim E, Otgontenger U, Jamsranjav A, Kim SS. Deleterious Alteration of Glia in the Brain of Alzheimer's Disease. International Journal of Molecular Sciences. 21. PMID 32932623 DOI: 10.3390/ijms21186676   
2020 Calvo-Rodriguez M, García-Rodríguez C, Villalobos C, Núñez L. Role of Toll Like Receptor 4 in Alzheimer's Disease. Frontiers in Immunology. 11: 1588. PMID 32983082 DOI: 10.3389/fimmu.2020.01588   
2020 Zhang J, Zhang J, Li XJ, Xiao J, Ye F. Hypoxic preconditioning ameliorates amyloid-β pathology and long-term cognitive decline in AβPP/PS1 transgenic mice. Current Alzheimer Research. PMID 33030131 DOI: 10.2174/1567205017666201007121730   
2020 Ju Y, Chakravarty H, Tam KY. An Isoquinolinium Dual Inhibitor of Cholinesterases and Amyloid β Aggregation Mitigates Neuropathological Changes in a Triple-Transgenic Mouse Model of Alzheimer's Disease. Acs Chemical Neuroscience. PMID 33001625 DOI: 10.1021/acschemneuro.0c00464   
2020 Costa AS, Agostini S, Guerini FR, Mancuso R, Clerici M, Pandey JP. Relation between FCGRIIB rs1050501 and HSV-1 specific IgG antibodies in Alzheimer's disease. Journal of Translational Medicine. 18: 325. PMID 32859213 DOI: 10.1186/s12967-020-02495-6   
2020 Wang ZX, Wan Q, Xing A. HLA in Alzheimer's Disease: Genetic Association and Possible Pathogenic Roles. Neuromolecular Medicine. PMID 32894413 DOI: 10.1007/s12017-020-08612-4   
2020 Xu X, Meng T, Wen Q, Tao M, Wang P, Zhong K, Shen Y. Dynamic changes in vascular size and density in transgenic mice with Alzheimer's disease. Aging. 12. PMID 32908022 DOI: 10.18632/aging.103672