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Eugene G. Mueller, Ph.D. - Publications

Affiliations: 
Chemistry University of Delaware, Newark, DE, United States 
Area:
Enzymology
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27 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Veerareddygari GR, Mueller EG. Kinetic Isotope Effect Studies to Elucidate the Reaction Mechanism of RNA-Modifying Enzymes. Methods in Enzymology. 596: 523-546. PMID 28911783 DOI: 10.1016/Bs.Mie.2017.07.018  0.474
2016 Veerareddygari GR, Klusman TC, Mueller EG. Characterization of the catalytic disulfide bond in E. coli 4-thiouridine synthetase to elucidate its functional quaternary structure. Protein Science : a Publication of the Protein Society. PMID 27293139 DOI: 10.1002/Pro.2965  0.416
2016 Veerareddygari GR, Singh SK, Mueller EG. The pseudouridine synthases proceed through a glycal intermediate. Journal of the American Chemical Society. PMID 27292228 DOI: 10.1021/Jacs.6B04491  0.455
2011 Miracco EJ, Bogdanov B, Mueller EG. Unexpected linear ion trap collision-induced dissociation and Fourier transform ion cyclotron resonance infrared multi-photon dissociation fragmentation of a hydrated C-glycoside of 5-fluorouridine formed by the action of the pseudouridine synthases RluA and TruB. Rapid Communications in Mass Spectrometry : Rcm. 25: 2627-32. PMID 23657957 DOI: 10.1002/Rcm.5162  0.759
2011 Miracco EJ, Mueller EG. The products of 5-fluorouridine by the action of the pseudouridine synthase TruB disfavor one mechanism and suggest another. Journal of the American Chemical Society. 133: 11826-9. PMID 21744792 DOI: 10.1021/Ja201179F  0.77
2011 McDonald MK, Miracco EJ, Chen J, Xie Y, Mueller EG. The handling of the mechanistic probe 5-fluorouridine by the pseudouridine synthase TruA and its consistency with the handling of the same probe by the pseudouridine synthases TruB and RluA. Biochemistry. 50: 426-36. PMID 21142053 DOI: 10.1021/Bi101737Z  0.783
2009 Mueller EG. Se-ing into selenocysteine biosynthesis. Nature Chemical Biology. 5: 611-2. PMID 19690534 DOI: 10.1038/Nchembio0909-611  0.435
2006 Hoang C, Chen J, Vizthum CA, Kandel JM, Hamilton CS, Mueller EG, Ferré-D'Amaré AR. Crystal structure of pseudouridine synthase RluA: indirect sequence readout through protein-induced RNA structure. Molecular Cell. 24: 535-45. PMID 17188032 DOI: 10.1016/J.Molcel.2006.09.017  0.661
2006 Hamilton CS, Greco TM, Vizthum CA, Ginter JM, Johnston MV, Mueller EG. Mechanistic investigations of the pseudouridine synthase RluA using RNA containing 5-fluorouridine. Biochemistry. 45: 12029-38. PMID 17002302 DOI: 10.1021/Bi061293X  0.662
2006 Wright CM, Christman GD, Snellinger AM, Johnston MV, Mueller EG. Direct evidence for enzyme persulfide and disulfide intermediates during 4-thiouridine biosynthesis. Chemical Communications (Cambridge, England). 3104-6. PMID 16855700 DOI: 10.1039/B604040C  0.629
2006 Mueller EG. Trafficking in persulfides: delivering sulfur in biosynthetic pathways. Nature Chemical Biology. 2: 185-94. PMID 16547481 DOI: 10.1038/Nchembio779  0.414
2005 Hoang C, Hamilton CS, Mueller EG, Ferré-D'Amaré AR. Precursor complex structure of pseudouridine synthase TruB suggests coupling of active site perturbations to an RNA-sequestering peripheral protein domain. Protein Science : a Publication of the Protein Society. 14: 2201-6. PMID 15987897 DOI: 10.1110/Ps.051493605  0.636
2005 Hamilton CS, Spedaliere CJ, Ginter JM, Johnston MV, Mueller EG. The roles of the essential Asp-48 and highly conserved His-43 elucidated by the pH dependence of the pseudouridine synthase TruB. Archives of Biochemistry and Biophysics. 433: 322-34. PMID 15581587 DOI: 10.1016/J.Abb.2004.09.009  0.755
2004 Spedaliere CJ, Ginter JM, Johnston MV, Mueller EG. The pseudouridine synthases: revisiting a mechanism that seemed settled. Journal of the American Chemical Society. 126: 12758-9. PMID 15469254 DOI: 10.1021/Ja046375S  0.768
2004 Spedaliere CJ, Mueller EG. Not all pseudouridine synthases are potently inhibited by RNA containing 5-fluorouridine. Rna (New York, N.Y.). 10: 192-9. PMID 14730018 DOI: 10.1261/Rna.5100104  0.753
2002 Wright CM, Palenchar PM, Mueller EG. A paradigm for biological sulfur transfers via persulfide groups: a persulfide-disulfide-thiol cycle in 4-thiouridine biosynthesis. Chemical Communications (Cambridge, England). 2708-9. PMID 12510310 DOI: 10.1039/B208626C  0.763
2002 Mueller EG. Chips off the old block. Nature Structural Biology. 9: 320-2. PMID 11976723 DOI: 10.1038/Nsb0502-320  0.465
2001 Mueller EG, Palenchar PM, Buck CJ. The role of the cysteine residues of ThiI in the generation of 4-thiouridine in tRNA. The Journal of Biological Chemistry. 276: 33588-95. PMID 11443125 DOI: 10.1074/Jbc.M104067200  0.766
2000 Spedaliere CJ, Hamilton CS, Mueller EG. Functional importance of motif I of pseudouridine synthases: mutagenesis of aligned lysine and proline residues. Biochemistry. 39: 9459-65. PMID 10924141 DOI: 10.1021/Bi001079N  0.763
2000 Palenchar PM, Buck CJ, Cheng H, Larson TJ, Mueller EG. Evidence that ThiI, an enzyme shared between thiamin and 4-thiouridine biosynthesis, may be a sulfurtransferase that proceeds through a persulfide intermediate. The Journal of Biological Chemistry. 275: 8283-6. PMID 10722656 DOI: 10.1074/Jbc.275.12.8283  0.778
1999 Mueller EG, Palenchar PM. Using genomic information to investigate the function of ThiI, an enzyme shared between thiamin and 4-thiouridine biosynthesis. Protein Science : a Publication of the Protein Society. 8: 2424-7. PMID 10595545 DOI: 10.1110/Ps.8.11.2424  0.783
1999 Ramamurthy V, Swann SL, Spedaliere CJ, Mueller EG. Role of cysteine residues in pseudouridine synthases of different families. Biochemistry. 38: 13106-11. PMID 10529181 DOI: 10.1021/Bi9913911  0.788
1999 Ramamurthy V, Swann SL, Paulson JL, Spedaliere CJ, Mueller EG. Critical aspartic acid residues in pseudouridine synthases. The Journal of Biological Chemistry. 274: 22225-30. PMID 10428788 DOI: 10.1074/Jbc.274.32.22225  0.784
1998 Mueller EG, Buck CJ, Palenchar PM, Barnhart LE, Paulson JL. Identification of a gene involved in the generation of 4-thiouridine in tRNA. Nucleic Acids Research. 26: 2606-10. PMID 9592144 DOI: 10.1093/Nar/26.11.2606  0.742
1993 Mueller EG, Crowder MW, Averill BA, Knowles JR. Purple acid phosphatase: a diiron enzyme that catalyzes a direct phospho group transfer to water Journal of the American Chemical Society. 115: 2974-2975. DOI: 10.1021/Ja00060A055  0.625
1993 Mueller EG, Crowder MW, Averill BA, Knowles JR. Purple acid phosphatase catalyzes the direct transfer of a phospho group from substrate to water. Journal of Inorganic Biochemistry. 51: 106. DOI: 10.1016/0162-0134(93)85142-U  0.58
1990 Mueller EG, Khandekar SS, Knowles JR, Jacobson GR. Stereochemical course of the reactions catalyzed by the bacterial phosphoenolpyruvate:mannitol phosphotransferase system. Biochemistry. 29: 6892-6. PMID 2118803 DOI: 10.1021/Bi00481A019  0.54
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