Stefan Prokop - Related publications

Affiliations: 
University of Pennsylvania, Philadelphia, PA, United States 
Area:
Microglia, Neurodegeneration, Alzheimer, Parkinsons
NOTE: We are testing a new system for identifying relevant work based on semantic analysis that identifies similarities between recently published papers and the current author's publications. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches.
50 most relevant papers in past 60 days:
Year Citation  Score
2020 Perea JR, Bolós M, Avila J. Microglia in Alzheimer's Disease in the Context of Tau Pathology. Biomolecules. 10. PMID 33066368 DOI: 10.3390/biom10101439   
2020 Garcia-Leon JA, Caceres-Palomo L, Sanchez-Mejias E, Mejias-Ortega M, Nuñez-Diaz C, Fernandez-Valenzuela JJ, Sanchez-Varo R, Davila JC, Vitorica J, Gutierrez A. Human Pluripotent Stem Cell-Derived Neural Cells as a Relevant Platform for Drug Screening in Alzheimer's Disease. International Journal of Molecular Sciences. 21. PMID 32962164 DOI: 10.3390/ijms21186867   
2020 Narayanan SE, Sekhar N, Rajamma RG, Marathakam A, Al Mamun A, Uddin MS, Mathew B. Exploring the Role of Aggregated Proteomes in the Pathogenesis of Alzheimer's Disease. Current Protein & Peptide Science. PMID 32957903 DOI: 10.2174/1389203721666200921152246   
2020 Qu X, Guan P, Han L, Wang Z, Huang X. Levistolide A Attenuates Alzheimer's Pathology Through Activation of the PPARγ Pathway. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. PMID 33034847 DOI: 10.1007/s13311-020-00943-1   
2020 d'Abramo C, D'Adamio L, Giliberto L. Significance of Blood and Cerebrospinal Fluid Biomarkers for Alzheimer's Disease: Sensitivity, Specificity and Potential for Clinical Use. Journal of Personalized Medicine. 10. PMID 32911755 DOI: 10.3390/jpm10030116   
2020 Chen XQ, Salehi A, Pearn ML, Overk C, Nguyen PD, Kleschevnikov AM, Maccecchini M, Mobley WC. Targeting increased levels of APP in Down syndrome: Posiphen-mediated reductions in APP and its products reverse endosomal phenotypes in the Ts65Dn mouse model. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 32975365 DOI: 10.1002/alz.12185   
2020 Barman NC, Khan NM, Islam M, Nain Z, Roy RK, Haque A, Barman SK. CRISPR-Cas9: A Promising Genome Editing Therapeutic Tool for Alzheimer's Disease-A Narrative Review. Neurology and Therapy. PMID 33089409 DOI: 10.1007/s40120-020-00218-z   
2020 Corsetti V, Borreca A, Latina V, Giacovazzo G, Pignataro A, Krashia P, Natale F, Cocco S, Rinaudo M, Malerba F, Florio R, Ciarapica R, Coccurello R, D'Amelio M, Ammassari-Teule M, et al. Passive immunotherapy for N-truncated tau ameliorates the cognitive deficits in two mouse Alzheimer's disease models. Brain Communications. 2: fcaa039. PMID 32954296 DOI: 10.1093/braincomms/fcaa039   
2020 Ma WH, Chen AF, Xie XY, Huang YS. Sigma ligands as potent inhibitors of Aβ and AβOs in neurons and promising therapeutic agents of Alzheimer's disease. Neuropharmacology. 108342. PMID 33045243 DOI: 10.1016/j.neuropharm.2020.108342   
2020 Poon CH, Wang Y, Fung ML, Zhang C, Lim LW. Rodent Models of Amyloid-Beta Feature of Alzheimer's Disease: Development and Potential Treatment Implications. Aging and Disease. 11: 1235-1259. PMID 33014535 DOI: 10.14336/AD.2019.1026   
2020 Ma Y, McClatchy DB, Martínez-Bartolomé S, Bamberger C, Yates JR. Temporal Quantitative Profiling of Newly Synthesized Proteins during Aβ Accumulation. Journal of Proteome Research. PMID 33147027 DOI: 10.1021/acs.jproteome.0c00645   
2020 Han F, Bi J, Qiao L, Arancio O. Stem Cell Therapy for Alzheimer's Disease. Advances in Experimental Medicine and Biology. 1266: 39-55. PMID 33105494 DOI: 10.1007/978-981-15-4370-8_4   
2020 Thompson TB, Chaggar P, Kuhl E, Goriely A, . Protein-protein interactions in neurodegenerative diseases: A conspiracy theory. Plos Computational Biology. 16: e1008267. PMID 33048932 DOI: 10.1371/journal.pcbi.1008267   
2020 Tan MS, Yang YX, Wang HF, Xu W, Tan CC, Zuo CT, Dong Q, Tan L, Yu JT, . PET Amyloid and Tau Status Are Differently Affected by Patient Features. Journal of Alzheimer's Disease : Jad. PMID 33104024 DOI: 10.3233/JAD-200124   
2020 Zhu F, Li C, Chu F, Tian X, Zhu J. Target Dysbiosis of Gut Microbes as a Future Therapeutic Manipulation in Alzheimer's Disease. Frontiers in Aging Neuroscience. 12: 544235. PMID 33132894 DOI: 10.3389/fnagi.2020.544235   
2020 Sun BL, Chen Y, Fan DY, Zhu C, Zeng F, Wang YJ. Critical thinking on amyloid-beta-targeted therapy: challenges and perspectives. Science China. Life Sciences. PMID 33106917 DOI: 10.1007/s11427-020-1810-y   
2020 Mo D, Li X, Raabe CA, Rozhdestvensky TS, Skryabin BV, Brosius J. Circular RNA Encoded Amyloid Beta peptides-A Novel Putative Player in Alzheimer's Disease. Cells. 9. PMID 33003364 DOI: 10.3390/cells9102196   
2020 Moynier F, Borgne ML, Laoud E, Mahan B, Mouton-Ligier F, Hugon J, Paquet C. Copper and zinc isotopic excursions in the human brain affected by Alzheimer's disease. Alzheimer's & Dementia (Amsterdam, Netherlands). 12: e12112. PMID 33102682 DOI: 10.1002/dad2.12112   
2020 Rivera-Marrero S, Bencomo-Martínez A, Orta Salazar E, Sablón-Carrazana M, García-Pupo L, Zoppolo F, Arredondo F, Dapueto R, Daniela Santi M, Kreimerman I, Pardo T, Reyes L, Galán L, León-Chaviano S, Espinosa-Rodríguez LA, et al. A new naphthalene derivative with anti-amyloidogenic activity as potential therapeutic agent for Alzheimer's disease. Bioorganic & Medicinal Chemistry. 28: 115700. PMID 33069076 DOI: 10.1016/j.bmc.2020.115700   
2020 Low CYB, Lee JH, Lim FTW, Lee C, Ballard C, Francis PT, Lai MKP, Tan MGK. Isoform-specific upregulation of FynT kinase expression is associated with tauopathy and glial activation in Alzheimer's disease and Lewy body dementias. Brain Pathology (Zurich, Switzerland). e12917. PMID 33128789 DOI: 10.1111/bpa.12917   
2020 Lewcock JW, Schlepckow K, Di Paolo G, Tahirovic S, Monroe KM, Haass C. Emerging Microglia Biology Defines Novel Therapeutic Approaches for Alzheimer's Disease. Neuron. PMID 33096024 DOI: 10.1016/j.neuron.2020.09.029   
2020 Dong CM, Guo AS, To A, Chan KWY, Chow ASF, Bian L, Leong ATL, Wu EX. Early Detection of Amyloid β Pathology in Alzheimer's Disease by Molecular MRI. Annual International Conference of the Ieee Engineering in Medicine and Biology Society. Ieee Engineering in Medicine and Biology Society. Annual International Conference. 2020: 1100-1103. PMID 33018178 DOI: 10.1109/EMBC44109.2020.9176013   
2020 Zhang T, Dong K, Xiao L, Li G, Zhang Z. Effects of Co-Administration of Icariin and Saponins on Intestinal Microbiota and Hippocampal Protein Expression in a Mouse Model of Alzheimer's Disease. Neuropsychiatric Disease and Treatment. 16: 2169-2179. PMID 33061388 DOI: 10.2147/NDT.S253972   
2020 Goedert M. Tau proteinopathies and the prion concept. Progress in Molecular Biology and Translational Science. 175: 239-259. PMID 32958235 DOI: 10.1016/bs.pmbts.2020.08.003   
2020 Alam J. Vitamins: a nutritional intervention to modulate the Alzheimer's disease progression. Nutritional Neuroscience. 1-18. PMID 32998670 DOI: 10.1080/1028415X.2020.1826762   
2020 Siano G, Varisco M, Scarlatti A, Caiazza MC, Dunville K, Cremisi F, Costa M, Pancrazi L, Di Primio C, Cattaneo A. Gene expression of disease-related genes in Alzheimer's disease is impaired by Tau aggregation. Journal of Molecular Biology. PMID 33058882 DOI: 10.1016/j.jmb.2020.10.009   
2020 Das S, Sengupta S, Chakraborty S. Scope of β-Secretase (BACE1)-Targeted Therapy in Alzheimer's Disease: Emphasizing the Flavonoid Based Natural Scaffold for BACE1 Inhibition. Acs Chemical Neuroscience. PMID 33073981 DOI: 10.1021/acschemneuro.0c00579   
2020 Osama A, Zhang J, Yao J, Yao X, Fang J. Nrf2: a dark horse in Alzheimer's disease treatment. Ageing Research Reviews. 101206. PMID 33144124 DOI: 10.1016/j.arr.2020.101206   
2020 Baek MS, Cho H, Lee HS, Lee JH, Ryu YH, Lyoo CH. Effect of APOE ε4 genotype on amyloid-β and tau accumulation in Alzheimer's disease. Alzheimer's Research & Therapy. 12: 140. PMID 33129364 DOI: 10.1186/s13195-020-00710-6   
2020 Dadar M, Camicioli R, Duchesne S, Collins DL, . The temporal relationships between white matter hyperintensities, neurodegeneration, amyloid beta, and cognition. Alzheimer's & Dementia (Amsterdam, Netherlands). 12: e12091. PMID 33083512 DOI: 10.1002/dad2.12091   
2020 Wang L, Bharti, Kumar R, Pavlov PF, Winblad B. Small molecule therapeutics for tauopathy in Alzheimer's disease: Walking on the path of most resistance. European Journal of Medicinal Chemistry. 112915. PMID 33139110 DOI: 10.1016/j.ejmech.2020.112915   
2020 Zhang Z, Sheng H, Liao L, Xu C, Zhang A, Yang Y, Zhao L, Duan L, Chen H, Zhang B. Mesenchymal Stem Cell-Conditioned Medium Improves Mitochondrial Dysfunction and Suppresses Apoptosis in Okadaic Acid-Treated SH-SY5Y Cells by Extracellular Vesicle Mitochondrial Transfer. Journal of Alzheimer's Disease : Jad. PMID 33104031 DOI: 10.3233/JAD-200686   
2020 Jo M, Lee S, Jeon YM, Kim S, Kwon Y, Kim HJ. The role of TDP-43 propagation in neurodegenerative diseases: integrating insights from clinical and experimental studies. Experimental & Molecular Medicine. PMID 33051572 DOI: 10.1038/s12276-020-00513-7   
2020 Tudorascu DL, Laymon CM, Zammit M, Minhas DS, Anderson SJ, Ellison PA, Zaman S, Ances BM, Sabbagh M, Johnson SC, Mathis CA, Klunk WE, Handen BL, Christian BT, Cohen AD. Relationship of amyloid beta and neurofibrillary tau deposition in Neurodegeneration in Aging Down Syndrome (NiAD) study at baseline. Alzheimer's & Dementia (New York, N. Y.). 6: e12096. PMID 33163613 DOI: 10.1002/trc2.12096   
2020 Zhang J, Zhang J, Li XJ, Xiao J, Ye F. Hypoxic preconditioning ameliorates amyloid-β pathology and long-term cognitive decline in AβPP/PS1 transgenic mice. Current Alzheimer Research. PMID 33030131 DOI: 10.2174/1567205017666201007121730   
2020 Roy ER, Cao W. Antiviral Immune Response in Alzheimer's Disease: Connecting the Dots. Frontiers in Neuroscience. 14: 577744. PMID 33132831 DOI: 10.3389/fnins.2020.577744   
2020 Therriault J, Pascoal TA, Savard M, Benedet AL, Chamoun M, Tissot C, Lussier F, Kang MS, Thomas E, Terada T, Rej S, Massarweh G, Nasreddine Z, Vitali P, Soucy JP, et al. Topographical distribution of amyloid-β, tau and atrophy in behavioral / dysexecutive AD patients. Neurology. PMID 33093220 DOI: 10.1212/WNL.0000000000011081   
2020 Wu J, Cao C, Loch RA, Tiiman A, Luo J. Single-molecule studies of amyloid proteins: from biophysical properties to diagnostic perspectives. Quarterly Reviews of Biophysics. 53: e12. PMID 33148356 DOI: 10.1017/S0033583520000086   
2020 Zhou Y, Zhu F, Liu Y, Zheng M, Wang Y, Zhang D, Anraku Y, Zou Y, Li J, Wu H, Pang X, Tao W, Shimoni O, Bush AI, Xue X, et al. Blood-brain barrier-penetrating siRNA nanomedicine for Alzheimer's disease therapy. Science Advances. 6. PMID 33036977 DOI: 10.1126/sciadv.abc7031   
2020 Bell BJ, Malvankar MM, Tallon C, Slusher BS. Sowing the Seeds of Discovery: Tau-Propagation Models of Alzheimer's Disease. Acs Chemical Neuroscience. PMID 33050700 DOI: 10.1021/acschemneuro.0c00531   
2020 Doustar J, Rentsendorj A, Torbati T, Regis GC, Fuchs DT, Sheyn J, Mirzaei N, Graham SL, Shah PK, Mastali M, Van Eyk JE, Black KL, Gupta VK, Mirzaei M, Koronyo Y, et al. Parallels between retinal and brain pathology and response to immunotherapy in old, late-stage Alzheimer's disease mouse models. Aging Cell. e13246. PMID 33090673 DOI: 10.1111/acel.13246   
2020 Hao F, Feng Y. Cannabidiol (CBD) enhanced the hippocampal immune response and autophagy of APP/PS1 Alzheimer's mice uncovered by RNA-seq. Life Sciences. 118624. PMID 33096116 DOI: 10.1016/j.lfs.2020.118624   
2020 Rafii MS, Ances BM, Schupf N, Krinsky-McHale SJ, Mapstone M, Silverman W, Lott I, Klunk W, Head E, Christian B, Lai F, Rosas HD, Zaman S, Petersen ME, Strydom A, et al. The AT(N) framework for Alzheimer's disease in adults with Down syndrome. Alzheimer's & Dementia (Amsterdam, Netherlands). 12: e12062. PMID 33134477 DOI: 10.1002/dad2.12062   
2020 Tan X, Liang Z, Li Y, Zhi Y, Yi L, Bai S, Forest KH, Nichols RA, Dong Y, Li QX. Isoorientin, a GSK-3β inhibitor, rescues synaptic dysfunction, spatial memory deficits and attenuates pathological progression in APP/PS1 model mice. Behavioural Brain Research. 112968. PMID 33069740 DOI: 10.1016/j.bbr.2020.112968   
2020 Akter R, Chowdhury MAR, Habib Ur Rahman M. Antioxidant as Talented Drug Applicants for the Treatment of Alzheimer's Disease and their Molecular Mechanism Insights. Current Pharmaceutical Design. PMID 33138754 DOI: 10.2174/1381612826666201102102810   
2020 Li S, Wang C, Wang W, Tan J. Trait anxiety, a personality risk factor associated with Alzheimer's Disease. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 110124. PMID 33035604 DOI: 10.1016/j.pnpbp.2020.110124   
2020 Scholes HM, Cryar A, Kerr F, Sutherland D, Gethings LA, Vissers JPC, Lees JG, Orengo CA, Partridge L, Thalassinos K. Dynamic changes in the brain protein interaction network correlates with progression of Aβ42 pathology in Drosophila. Scientific Reports. 10: 18517. PMID 33116184 DOI: 10.1038/s41598-020-74748-9   
2020 Kong F, Jiang X, Wang R, Zhai S, Zhang Y, Wang D. Forsythoside B attenuates memory impairment and neuroinflammation via inhibition on NF-κB signaling in Alzheimer's disease. Journal of Neuroinflammation. 17: 305. PMID 33059746 DOI: 10.1186/s12974-020-01967-2   
2020 Tackenberg C, Kulic L, Nitsch RM. Familial Alzheimer's disease mutations at position 22 of the amyloid β-peptide sequence differentially affect synaptic loss, tau phosphorylation and neuronal cell death in an ex vivo system. Plos One. 15: e0239584. PMID 32966331 DOI: 10.1371/journal.pone.0239584   
2020 Marschall P, Wei R, Segaud J, Yao W, Hener P, German BF, Meyer P, Hugel C, Da Silva GA, Braun R, Kaplan DH, Li M. Dual function of Langerhans cells in skin TSLP-promoted Tfh cell differentiation in mouse atopic dermatitis. The Journal of Allergy and Clinical Immunology. PMID 33068561 DOI: 10.1016/j.jaci.2020.10.006