Year |
Citation |
Score |
2019 |
Carreras-Sureda A, Jaña F, Urra H, Durand S, Mortenson DE, Sagredo A, Bustos G, Hazari Y, Ramos-Fernández E, Sassano ML, Pihán P, van Vliet AR, González-Quiroz M, Torres AK, Tapia-Rojas C, ... ... Inestrosa NC, et al. Publisher Correction: Non-canonical function of IRE1α determines mitochondria-associated endoplasmic reticulum composition to control calcium transfer and bioenergetics. Nature Cell Biology. PMID 31201389 DOI: 10.1038/S41556-019-0355-9 |
0.523 |
|
2019 |
Carreras-Sureda A, Jaña F, Urra H, Durand S, Mortenson DE, Sagredo A, Bustos G, Hazari Y, Ramos-Fernández E, Sassano ML, Pihán P, van Vliet AR, González-Quiroz M, Torres AK, Tapia-Rojas C, ... ... Inestrosa NC, et al. Non-canonical function of IRE1α determines mitochondria-associated endoplasmic reticulum composition to control calcium transfer and bioenergetics. Nature Cell Biology. PMID 31110288 DOI: 10.1038/S41556-019-0329-Y |
0.543 |
|
2016 |
Ramos-Fernández E, Tajes M, Ill-Raga G, Vargas L, Busquets-García A, Bosch-Morató M, Guivernau B, Valls-Comamala V, Gomis M, Grau C, Fandos C, Rosen MD, Rabinowitz MH, Inestrosa N, Maldonado R, et al. Glutamatergic stimulation induces GluN2B translation by the nitric oxide-Heme-Regulated eIF2α kinase in cortical neurons. Oncotarget. PMID 27557499 DOI: 10.18632/Oncotarget.11417 |
0.345 |
|
2015 |
Fuenzalida M, Espinoza C, Pérez MÁ, Tapia-Rojas C, Cuitino L, Brandan E, Inestrosa NC. Wnt signaling pathway improves central inhibitory synaptic transmission in a mouse model of Duchenne muscular dystrophy. Neurobiology of Disease. PMID 26626079 DOI: 10.1016/J.Nbd.2015.11.018 |
0.58 |
|
2015 |
Parodi J, Montecinos-Oliva C, Varas R, Alfaro IE, Serrano FG, Varas-Godoy M, Muñoz FJ, Cerpa W, Godoy JA, Inestrosa NC. Wnt5a inhibits K(+) currents in hippocampal synapses through nitric oxide production. Molecular and Cellular Neurosciences. 68: 314-22. PMID 26311509 DOI: 10.1016/J.Mcn.2015.08.011 |
0.713 |
|
2015 |
Alfaro IE, Varela-Nallar L, Varas-Godoy M, Inestrosa NC. The ROR2 tyrosine kinase receptor regulates dendritic spine morphogenesis in hippocampal neurons. Molecular and Cellular Neurosciences. 67: 22-30. PMID 26003414 DOI: 10.1016/j.mcn.2015.05.002 |
0.718 |
|
2015 |
Parodi J, Montecinos-Oliva C, Varas R, Alfaro IE, Serrano FG, Varas-Godoy M, Muñoz FJ, Cerpa W, Godoy JA, Inestrosa NC. Wnt5a inhibits K+ currents in hippocampal synapses through nitric oxide production Molecular and Cellular Neuroscience. 68: 314-322. DOI: 10.1016/j.mcn.2015.08.011 |
0.673 |
|
2014 |
Cisternas P, Henriquez JP, Brandan E, Inestrosa NC. Wnt signaling in skeletal muscle dynamics: myogenesis, neuromuscular synapse and fibrosis. Molecular Neurobiology. 49: 574-89. PMID 24014138 DOI: 10.1007/S12035-013-8540-5 |
0.58 |
|
2013 |
Quintanilla RA, Godoy JA, Alfaro I, Cabezas D, von Bernhardi R, Bronfman M, Inestrosa NC. Thiazolidinediones promote axonal growth through the activation of the JNK pathway. Plos One. 8: e65140. PMID 23741474 DOI: 10.1371/Journal.Pone.0065140 |
0.681 |
|
2011 |
Cerpa W, Gambrill A, Inestrosa NC, Barria A. Regulation of NMDA-receptor synaptic transmission by Wnt signaling. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 9466-71. PMID 21715611 DOI: 10.1523/Jneurosci.6311-10.2011 |
0.69 |
|
2011 |
Mesa R, Luo S, Hoover CM, Miller K, Minniti A, Inestrosa N, Nonet ML. HID-1, a new component of the peptidergic signaling pathway. Genetics. 187: 467-83. PMID 21115972 DOI: 10.1534/Genetics.110.121996 |
0.356 |
|
2010 |
Varela-Nallar L, Alfaro IE, Serrano FG, Parodi J, Inestrosa NC. Wingless-type family member 5A (Wnt-5a) stimulates synaptic differentiation and function of glutamatergic synapses. Proceedings of the National Academy of Sciences of the United States of America. 107: 21164-9. PMID 21084636 DOI: 10.1073/pnas.1010011107 |
0.707 |
|
2010 |
Reale M, Brenner T, Greig NH, Inestrosa N, Paleacu D. Neuroinflammation, AD, and Dementia. International Journal of Alzheimer's Disease. 2010. PMID 20871836 DOI: 10.4061/2010/974026 |
0.303 |
|
2009 |
Varela-Nallar L, Grabowski CP, Alfaro IE, Alvarez AR, Inestrosa NC. Role of the Wnt receptor Frizzled-1 in presynaptic differentiation and function. Neural Development. 4: 41. PMID 19883499 DOI: 10.1186/1749-8104-4-41 |
0.73 |
|
2009 |
FarÃas GG, Alfaro IE, Cerpa W, Grabowski CP, Godoy JA, Bonansco C, Inestrosa NC. Wnt-5a/JNK signaling promotes the clustering of PSD-95 in hippocampal neurons. The Journal of Biological Chemistry. 284: 15857-66. PMID 19332546 DOI: 10.1074/Jbc.M808986200 |
0.717 |
|
2008 |
Colombres M, HenrÃquez JP, Reig GF, Scheu J, Calderón R, Alvarez A, Brandan E, Inestrosa NC. Heparin activates Wnt signaling for neuronal morphogenesis. Journal of Cellular Physiology. 216: 805-15. PMID 18449906 DOI: 10.1002/Jcp.21465 |
0.557 |
|
2008 |
Cerpa W, Godoy JA, Alfaro I, FarÃas GG, Metcalfe MJ, Fuentealba R, Bonansco C, Inestrosa NC. Wnt-7a modulates the synaptic vesicle cycle and synaptic transmission in hippocampal neurons. The Journal of Biological Chemistry. 283: 5918-27. PMID 18096705 DOI: 10.1074/Jbc.M705943200 |
0.717 |
|
2004 |
Aldunate R, Casar JC, Brandan E, Inestrosa NC. Structural and functional organization of synaptic acetylcholinesterase Brain Research Reviews. 47: 96-104. PMID 15572165 DOI: 10.1016/J.Brainresrev.2004.07.019 |
0.593 |
|
2004 |
Casar JC, Cabello-Verrugio C, Olguin H, Aldunate R, Inestrosa NC, Brandan E. Heparan sulfate proteoglycans are increased during skeletal muscle regeneration: Requirement of syndecan-3 for successful fiber formation Journal of Cell Science. 117: 73-84. PMID 14627628 DOI: 10.1242/Jcs.00828 |
0.561 |
|
1998 |
Casanueva OI, García-Huidobro T, Campos EO, Aldunate R, Garrido J, Inestrosa NC. A major portion of synaptic basal lamina acetylcholinesterase is detached by high salt- and heparin-containing buffers from rat diaphragm muscle and Torpedo electric organ. The Journal of Biological Chemistry. 273: 4258-65. PMID 9461624 DOI: 10.1074/jbc.273.7.4258 |
0.308 |
|
1995 |
Rodriguez SR, Riquelme C, Campos EO, Chavez P, Brandan E, Inestrosa NC. Behavioral Responses of Concholepas concholepas (Bruguière, 1789) Larvae to Natural and Artificial Settlement Cues and Microbial Films. The Biological Bulletin. 189: 272-279. PMID 29244580 DOI: 10.2307/1542144 |
0.487 |
|
1993 |
Brandan E, Inestrosa NC. Extracellular matrix components and amyloid in neuritic plaques of Alzheimer's disease. General Pharmacology. 24: 1063-8. PMID 8270163 DOI: 10.1016/0306-3623(93)90350-7 |
0.512 |
|
1993 |
Krauss RY, Alvarez J, Inestrosa NC. A neurofilament polypeptide and the glial fibrillary acidic protein share common epitopes in the variable region. Neuroscience Letters. 161: 137-40. PMID 7505907 |
0.474 |
|
1992 |
Gonzalez R, Urrea R, Gonzalez M, Inestrosa NC, Brandan E. Isolation of proteoglycans synthesized by rat heart: evidence for the presence of several distinct forms. General Pharmacology. 23: 249-55. PMID 1639240 DOI: 10.1016/0306-3623(92)90020-K |
0.505 |
|
1992 |
Brandan E, González M, Inestrosa NC, Tremblay C, Urrea R. A high molecular weight proteoglycan is differentially expressed during development of the mollusc Concholepas concholepas (Mollusca; Gastropoda; Muricidae). The Journal of Experimental Zoology. 264: 363-71. PMID 1460434 DOI: 10.1002/Jez.1402640402 |
0.531 |
|
1992 |
Alvarez J, Moreno RD, Llanos O, Inestrosa NC, Brandan E, Colby T, Esch FS. Axonal sprouting induced in the sciatic nerve by the amyloid precursor protein (APP) and other antiproteases. Neuroscience Letters. 144: 130-4. PMID 1436693 DOI: 10.1016/0304-3940(92)90733-N |
0.518 |
|
1990 |
Fadic R, Brandan E, Inestrosa NC. Motor nerve regulates muscle extracellular matrix proteoglycan expression. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 10: 3516-23. PMID 2230941 DOI: 10.1523/Jneurosci.10-11-03516.1990 |
0.582 |
|
1990 |
Perelman A, Abeijon C, Hirschberg CB, Inestrosa NC, Brandan E. Differential association and distribution of acetyl- and butyrylcholinesterases within rat liver subcellular organelles. The Journal of Biological Chemistry. 265: 214-20. PMID 2152920 |
0.518 |
|
1990 |
Inestrosa NC, Labarca R, Perelman A, Campos EO, Araneda R, Gonzalez M, Brandan E, Sanchez JP, Gonzalez-Plaza R. Biotechnological aspects in loco larvae Archivos De Biologia Y Medicina Experimentales. 23: 179-186. PMID 1966831 |
0.515 |
|
1990 |
Brandan E, González M, González-Plaza R, Inestrosa NC. Increase of macromolecule synthesis after hatching of Concholepas concholepas veliger larvae: Effect of sulfate in the synthesis of proteoglycans Comparative Biochemistry and Physiology -- Part B: Biochemistry And. 96: 613-619. DOI: 10.1016/0305-0491(90)90065-2 |
0.508 |
|
1990 |
Gonzalez M, Perelman A, Fuentes ME, Castilla JC, Labarca R, Brandan E, Gonzalez-Plaza R, Inestrosa NC. Neurotransmitter-related enzyme acetylcholinesterase in juveniles of Concholepas concholepas (mollusca; gastropoda; muricidae) Journal of Experimental Zoology. 255: 1-8. DOI: 10.1002/Jez.1402550102 |
0.528 |
|
1989 |
Allende ML, Krauss RY, Tremblay C, Alvarez J, Inestrosa NC. Anti-200 kDa neurofilament antibody cross-reacts with microtubule-associated protein-2 (MAP-2). Journal of Neuroscience Research. 22: 130-3. PMID 2468783 DOI: 10.1002/Jnr.490220204 |
0.493 |
|
1987 |
Brandan E, Inestrosa NC. Co-solubilization of asymmetric acetylcholinesterase and dermatan sulfate proteoglycan from the extracellular matrix of rat skeletal muscles. Febs Letters. 213: 159-63. PMID 3556575 DOI: 10.1016/0014-5793(87)81483-7 |
0.562 |
|
1987 |
Brandan E, Inestrosa NC. Isolation of the heparan sulfate proteoglycans from the extracellular matrix of rat skeletal muscle. Journal of Neurobiology. 18: 271-82. PMID 2955079 DOI: 10.1002/Neu.480180303 |
0.568 |
|
1987 |
Cross D, Allende ML, Krauss RY, Fuentes ME, Kaltwasser G, Alvarez J, Inestrosa NC. Biosynthesis of the neurofilament heavy subunit in Xenopus oocytes microinjected with rat brain poly(A)+ RNA. Molecular Biology Reports. 12: 265-71. PMID 2893252 DOI: 10.1007/Bf00444678 |
0.471 |
|
1987 |
Inestrosa NC, Nader HB, Garrido J, Sampaio LO, Brandan E, Dietrich CP. Glycosaminoglycan composition of electric organ basement membranes. Journal of Neuroscience Research. 17: 256-64. PMID 2439701 DOI: 10.1002/Jnr.490170309 |
0.502 |
|
1986 |
Brandan E, Llona I, Inestrosa NC. Heparin-acetylcholinesterase interaction: Specific detachment of class I-A forms and binding of class I and II-A forms to heparin-agarose. Neurochemistry International. 9: 75-84. PMID 20493103 DOI: 10.1016/0197-0186(86)90034-3 |
0.52 |
|
1986 |
Brandan E, Inestrosa NC. The synaptic form of acetylcholinesterase binds to cell-surface heparan sulfate proteoglycans. Journal of Neuroscience Research. 15: 185-96. PMID 2937928 DOI: 10.1002/Jnr.490150208 |
0.557 |
|
1985 |
Brandan E, Maldonado M, Garrido J, Inestrosa NC. Anchorage of collagen-tailed acetylcholinesterase to the extracellular matrix is mediated by heparan sulfate proteoglycans. The Journal of Cell Biology. 101: 985-92. PMID 3161900 DOI: 10.1083/Jcb.101.3.985 |
0.557 |
|
1985 |
Inestrosa NC, Matthew WD, Reiness CG, Hall ZW, Reichardt LF. Atypical distribution of asymmetric acetylcholinesterase in mutant PC12 pheochromocytoma cells lacking a cell surface heparan sulfate proteoglycan. Journal of Neurochemistry. 45: 86-94. PMID 3158721 DOI: 10.1111/j.1471-4159.1985.tb05478.x |
0.538 |
|
1984 |
Ziskind-Conhaim L, Inestrosa NC, Hall ZW. Acetylcholinesterase is functional in embryonic rat muscle before its accumulation at the sites of nerve-muscle contact. Developmental Biology. 103: 369-77. PMID 6202574 DOI: 10.1016/0012-1606(84)90325-7 |
0.556 |
|
1984 |
Brandan E, Inestrosa NC. Binding of the asymmetric forms of acetylcholinesterase to heparin. The Biochemical Journal. 221: 415-22. PMID 6089739 DOI: 10.1042/Bj2210415 |
0.545 |
|
1983 |
Inestrosa NC, Miller JB, Silberstein L, Ziskind-Conhaim L, Hall ZW. Developmental regulation of 16S acetylcholinesterase and acetylcholine receptors in a mouse muscle cell line. Experimental Cell Research. 147: 393-405. PMID 6617773 DOI: 10.1016/0014-4827(83)90221-5 |
0.567 |
|
1982 |
Silberstein L, Inestrosa NC, Hall ZW. Aneural muscle cell cultures make synaptic basal lamina components. Nature. 295: 143-5. PMID 7035963 DOI: 10.1038/295143a0 |
0.617 |
|
1982 |
Inestrosa NC, Silberstein L, Hall ZW. Association of the synaptic form of acetylcholinesterase with extracellular matrix in cultured mouse muscle cells. Cell. 29: 71-9. PMID 6286145 DOI: 10.1016/0092-8674(82)90091-5 |
0.564 |
|
1981 |
Inestrosa NC, Reiness CG, Reichardt LF, Hall ZW. Cellular localization of the molecular forms of acetylcholinesterase in rat pheochromocytoma PC12 cells treated with nerve growth factor. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 1: 1260-7. PMID 7310486 DOI: 10.1523/Jneurosci.01-11-01260.1981 |
0.588 |
|
1979 |
Inestrosa NC, Mendez B, Luco JV. Acetylcholinesterase like that of skeletal muscle in smooth muscle reinnervated by a motor nerve. Nature. 280: 504-6. PMID 460431 DOI: 10.1038/280504A0 |
0.643 |
|
Low-probability matches (unlikely to be authored by this person) |
1991 |
von Bernhardi R, Inestrosa NC. Dermatan sulfate and de-sulfated heparin solubilized collagen-tailed acetylcholinesterase from the rat neuromuscular junction. Brain Research. 529: 91-5. PMID 2282507 DOI: 10.1016/0006-8993(90)90814-R |
0.293 |
|
1983 |
Torres JC, Inestrosa NC. Heparin solubilizes asymmetric acetylcholinesterase from rat neuromuscular junction. Febs Letters. 154: 265-8. PMID 6832369 DOI: 10.1016/0014-5793(83)80162-8 |
0.282 |
|
2022 |
Bonansco C, Cerpa W, Inestrosa NC. How Are Synapses Born? A Functional and Molecular View of the Role of the Wnt Signaling Pathway. International Journal of Molecular Sciences. 24. PMID 36614149 DOI: 10.3390/ijms24010708 |
0.279 |
|
2018 |
Lira M, Arancibia D, Orrego PR, Montenegro-Venegas C, Cruz Y, García J, Leal-Ortiz S, Godoy JA, Gundelfinger ED, Inestrosa NC, Garner CC, Zamorano P, Torres VI. The Exocyst Component Exo70 Modulates Dendrite Arbor Formation, Synapse Density, and Spine Maturation in Primary Hippocampal Neurons. Molecular Neurobiology. PMID 30374940 DOI: 10.1007/s12035-018-1378-0 |
0.277 |
|
2014 |
Bustos FJ, Varela-Nallar L, Campos M, Henriquez B, Phillips M, Opazo C, Aguayo LG, Montecino M, Constantine-Paton M, Inestrosa NC, van Zundert B. PSD95 suppresses dendritic arbor development in mature hippocampal neurons by occluding the clustering of NR2B-NMDA receptors. Plos One. 9: e94037. PMID 24705401 DOI: 10.1371/journal.pone.0094037 |
0.277 |
|
2015 |
Dinamarca MC, Di Luca M, Godoy JA, Inestrosa NC. The soluble extracellular fragment of neuroligin-1 targets Aβ oligomers to the postsynaptic region of excitatory synapses. Biochemical and Biophysical Research Communications. 466: 66-71. PMID 26325471 DOI: 10.1016/j.bbrc.2015.08.107 |
0.276 |
|
2010 |
Cerpa W, Farías GG, Godoy JA, Fuenzalida M, Bonansco C, Inestrosa NC. Wnt-5a occludes Abeta oligomer-induced depression of glutamatergic transmission in hippocampal neurons. Molecular Neurodegeneration. 5: 3. PMID 20205789 DOI: 10.1186/1750-1326-5-3 |
0.275 |
|
2010 |
Inestrosa NC, Arenas E. Emerging roles of Wnts in the adult nervous system. Nature Reviews. Neuroscience. 11: 77-86. PMID 20010950 DOI: 10.1038/Nrn2755 |
0.275 |
|
2019 |
Martinez M, Torres VI, Vio CP, Inestrosa NC. Canonical Wnt Signaling Modulates the Expression of Pre- and Postsynaptic Components in Different Temporal Patterns. Molecular Neurobiology. PMID 31745835 DOI: 10.1007/s12035-019-01785-5 |
0.273 |
|
1995 |
Deprez PN, Inestrosa NC. Two heparin-binding domains are present on the collagenic tail of asymmetric acetylcholinesterase. The Journal of Biological Chemistry. 270: 11043-6. PMID 7744733 DOI: 10.1074/Jbc.270.19.11043 |
0.273 |
|
2016 |
Ramírez VT, Ramos-Fernández E, Inestrosa NC. The Gα o Activator Mastoparan-7 Promotes Dendritic Spine Formation in Hippocampal Neurons. Neural Plasticity. 2016: 4258171. PMID 26881110 DOI: 10.1155/2016/4258171 |
0.269 |
|
2012 |
Varela-Nallar L, Ramirez VT, Gonzalez-Billault C, Inestrosa NC. Frizzled receptors in neurons: from growth cones to the synapse. Cytoskeleton (Hoboken, N.J.). 69: 528-34. PMID 22407911 DOI: 10.1002/Cm.21022 |
0.267 |
|
2022 |
Álvarez-Ferradas C, Wellmann M, Morales K, Fuenzalida M, Cerpa W, Inestrosa NC, Bonansco C. Wnt-5a induces the conversion of silent to functional synapses in the hippocampus. Frontiers in Molecular Neuroscience. 15: 1024034. PMID 36385757 DOI: 10.3389/fnmol.2022.1024034 |
0.266 |
|
2008 |
Dinamarca MC, Colombres M, Cerpa W, Bonansco C, Inestrosa NC. Beta-amyloid oligomers affect the structure and function of the postsynaptic region: role of the Wnt signaling pathway. Neuro-Degenerative Diseases. 5: 149-52. PMID 18322375 DOI: 10.1159/000113687 |
0.266 |
|
2013 |
Oliva CA, Vargas JY, Inestrosa NC. Wnts in adult brain: from synaptic plasticity to cognitive deficiencies. Frontiers in Cellular Neuroscience. 7: 224. PMID 24348327 DOI: 10.3389/fncel.2013.00224 |
0.266 |
|
2016 |
Vallejo D, Codocedo JF, Inestrosa NC. Posttranslational Modifications Regulate the Postsynaptic Localization of PSD-95. Molecular Neurobiology. PMID 26884267 DOI: 10.1007/s12035-016-9745-1 |
0.264 |
|
2011 |
Rebolledo DL, Aldunate R, Kohn R, Neira I, Minniti AN, Inestrosa NC. Copper reduces Aβ oligomeric species and ameliorates neuromuscular synaptic defects in a C. elegans model of inclusion body myositis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 10149-58. PMID 21752991 DOI: 10.1523/JNEUROSCI.0336-11.2011 |
0.263 |
|
2012 |
Varela-Nallar L, Parodi J, FarÃas GG, Inestrosa NC. Wnt-5a is a synaptogenic factor with neuroprotective properties against Aβ toxicity. Neuro-Degenerative Diseases. 10: 23-6. PMID 22261402 DOI: 10.1159/000333360 |
0.263 |
|
1993 |
Rodriguez S, Ojeda F, Inestrosa N. Settlement of benthic marine invertebrates Marine Ecology Progress Series. 97: 193-207. DOI: 10.3354/Meps097193 |
0.262 |
|
2016 |
Ramírez VT, Ramos-Fernández E, Henríquez JP, Lorenzo A, Inestrosa NC. Wnt-5a/Frizzled9 receptor signaling through the Gαo/Gβγ complex regulates dendritic spine formation. The Journal of Biological Chemistry. PMID 27402827 DOI: 10.1074/jbc.M116.722132 |
0.261 |
|
2018 |
Zolezzi JM, Lindsay CB, Serrano FG, Ureta RC, Theoduloz C, Schmeda-Hirschmann G, Inestrosa NC. Neuroprotective Effects of Ferruginol, Jatrophone, and Junicedric Acid Against Amyloid-β Injury in Hippocampal Neurons. Journal of Alzheimer's Disease : Jad. PMID 29660932 DOI: 10.3233/JAD-170701 |
0.259 |
|
2009 |
Cerpa W, Toledo EM, Varela-Nallar L, Inestrosa NC. The role of Wnt signaling in neuroprotection. Drug News & Perspectives. 22: 579-91. PMID 20140278 DOI: 10.1358/Dnp.2009.22.10.1443391 |
0.258 |
|
2012 |
Dinamarca MC, Ríos JA, Inestrosa NC. Postsynaptic Receptors for Amyloid-β Oligomers as Mediators of Neuronal Damage in Alzheimer's Disease. Frontiers in Physiology. 3: 464. PMID 23267328 DOI: 10.3389/fphys.2012.00464 |
0.258 |
|
2017 |
Torres VI, Vallejo D, Inestrosa NC. Emerging Synaptic Molecules as Candidates in the Etiology of Neurological Disorders. Neural Plasticity. 2017: 8081758. PMID 28331639 DOI: 10.1155/2017/8081758 |
0.258 |
|
2021 |
Ramos-Fernández E, Arrázola MS, Oliva CA, Arredondo SB, Varela-Nallar L, Inestrosa NC. Wnt5a promotes hippocampal postsynaptic development and GluN2B-induced expression via the eIF2α HRI kinase. Scientific Reports. 11: 7395. PMID 33795747 DOI: 10.1038/s41598-021-86708-y |
0.255 |
|
2014 |
Vargas LM, Leal N, Estrada LD, González A, Serrano F, Araya K, Gysling K, Inestrosa NC, Pasquale EB, Alvarez AR. EphA4 activation of c-Abl mediates synaptic loss and LTP blockade caused by amyloid-β oligomers. Plos One. 9: e92309. PMID 24658113 DOI: 10.1371/journal.pone.0092309 |
0.254 |
|
2006 |
Colombres M, Bejide M, Inestrosa N. AbstractPoster presentation: Tuesday posterP3-345: The Wnt-signaling pathway modulates the biochemical properties of N-cadherin. It’s implications on Alzheimer’s disease Alzheimers & Dementia. 2. DOI: 10.1016/J.Jalz.2006.05.1615 |
0.252 |
|
2015 |
Inestrosa NC, Varela-Nallar L. Wnt signalling in neuronal differentiation and development. Cell and Tissue Research. 359: 215-23. PMID 25234280 DOI: 10.1007/s00441-014-1996-4 |
0.25 |
|
2015 |
Salech F, Varela-Nallar L, Arredondo S, Bustamante D, Vega DPdl, Inestrosa N, Behrens MI, Couve A. The role of klotho in the regulation of adult hippocampal neurogenesis Journal of the Neurological Sciences. 357. DOI: 10.1016/J.Jns.2015.08.865 |
0.25 |
|
2021 |
Vallejo D, Lindsay CB, González-Billault C, Inestrosa NC. Wnt5a modulates dendritic spine dynamics through the regulation of Cofilin via small Rho GTPase activity in hippocampal neurons. Journal of Neurochemistry. PMID 34107066 DOI: 10.1111/jnc.15448 |
0.249 |
|
1991 |
von Bernhardi R, Ayal H, Inestrosa NC. Carrageenans solubilize asymmetric acetylcholinesterase from nicotinic cholinergic synapses. Comparative Biochemistry and Physiology. C, Comparative Pharmacology and Toxicology. 96: 77-81. PMID 1980885 DOI: 10.1016/0742-8413(90)90047-D |
0.246 |
|
2010 |
Cuitino L, Godoy JA, FarÃas GG, Couve A, Bonansco C, Fuenzalida M, Inestrosa NC. Wnt-5a modulates recycling of functional GABAA receptors on hippocampal neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 8411-20. PMID 20573888 DOI: 10.1523/JNEUROSCI.5736-09.2010 |
0.242 |
|
2013 |
Rosso SB, Inestrosa NC. WNT signaling in neuronal maturation and synaptogenesis. Frontiers in Cellular Neuroscience. 7: 103. PMID 23847469 DOI: 10.3389/fncel.2013.00103 |
0.239 |
|
2014 |
Vargas JY, Fuenzalida M, Inestrosa NC. In vivo activation of Wnt signaling pathway enhances cognitive function of adult mice and reverses cognitive deficits in an Alzheimer's disease model. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 2191-202. PMID 24501359 DOI: 10.1523/JNEUROSCI.0862-13.2014 |
0.239 |
|
2014 |
Muñoz FJ, Godoy JA, Cerpa W, Poblete IM, Huidobro-Toro JP, Inestrosa NC. Wnt-5a increases NO and modulates NMDA receptor in rat hippocampal neurons. Biochemical and Biophysical Research Communications. 444: 189-94. PMID 24440698 DOI: 10.1016/J.Bbrc.2014.01.031 |
0.237 |
|
1988 |
Fadić R, Soza MA, Inestrosa NC. Changes in contralateral synaptic acetylcholinesterase following motor nerve section in rats. Neuroscience Letters. 90: 229-33. PMID 3412647 DOI: 10.1016/0304-3940(88)90817-8 |
0.237 |
|
2011 |
Dinamarca MC, Weinstein D, Monasterio O, Inestrosa NC. The synaptic protein neuroligin-1 interacts with the amyloid β-peptide. Is there a role in Alzheimer's disease? Biochemistry. 50: 8127-37. PMID 21838267 DOI: 10.1021/Bi201246T |
0.237 |
|
2015 |
Codocedo JF, Montecinos-Oliva C, Inestrosa NC. Wnt-related SynGAP1 is a neuroprotective factor of glutamatergic synapses against Aβ oligomers. Frontiers in Cellular Neuroscience. 9: 227. PMID 26124704 DOI: 10.3389/fncel.2015.00227 |
0.237 |
|
2014 |
Cerpa W, Ramos-Fernández E, Inestrosa NC. Modulation of the NMDA Receptor Through Secreted Soluble Factors. Molecular Neurobiology. PMID 25429903 DOI: 10.1007/S12035-014-9009-X |
0.235 |
|
2015 |
Vargas JY, Ahumada J, Arrázola MS, Fuenzalida M, Inestrosa NC. WASP-1, a canonical Wnt signaling potentiator, rescues hippocampal synaptic impairments induced by Aβ oligomers. Experimental Neurology. 264: 14-25. PMID 25450465 DOI: 10.1016/j.expneurol.2014.11.005 |
0.235 |
|
1996 |
Martínez G, Saleh F, Mettifogo L, Campos E, Inestrosa N. Monoamines and the release of gametes by the scallopArgopecten purpuratus The Journal of Experimental Zoology. 274: 365-372. DOI: 10.1002/(Sici)1097-010X(19960415)274:6<365::Aid-Jez5>3.0.Co;2-M |
0.234 |
|
2012 |
Aldunate R, Minniti AN, Rebolledo D, Inestrosa NC. Synaptic defects associated with s-inclusion body myositis are prevented by copper. Biometals : An International Journal On the Role of Metal Ions in Biology, Biochemistry, and Medicine. 25: 815-24. PMID 22573194 DOI: 10.1007/s10534-012-9553-7 |
0.234 |
|
2013 |
Oliva CA, Vargas JY, Inestrosa NC. Wnt signaling: role in LTP, neural networks and memory. Ageing Research Reviews. 12: 786-800. PMID 23665425 DOI: 10.1016/j.arr.2013.03.006 |
0.234 |
|
1985 |
Fernandez HL, Inestrosa NC, Stiles JR. Subcellular localization of acetylcholinesterase molecular forms in endplate regions of adult mammalian skeletal muscle. Neurochemical Research. 9: 1211-30. PMID 6504236 DOI: 10.1007/BF00973035 |
0.234 |
|
1998 |
Casanueva OI, Deprez P, García-Huidobro T, Inestrosa NC. At least two receptors of asymmetric acetylcholinesterase are present at the synaptic basal lamina of Torpedo electric organ. Biochemical and Biophysical Research Communications. 250: 312-7. PMID 9753626 DOI: 10.1006/bbrc.1998.9303 |
0.231 |
|
2016 |
Posada-Duque RA, Ramirez O, Härtel S, Inestrosa NC, Bodaleo F, González-Billault C, Kirkwood A, Cardona-Gómez GP. CDK5 downregulation enhances synaptic plasticity. Cellular and Molecular Life Sciences : Cmls. PMID 27506619 DOI: 10.1007/S00018-016-2333-8 |
0.23 |
|
2017 |
Torres VI, Inestrosa NC. Vertebrate Presynaptic Active Zone Assembly: a Role Accomplished by Diverse Molecular and Cellular Mechanisms. Molecular Neurobiology. PMID 28685386 DOI: 10.1007/s12035-017-0661-9 |
0.228 |
|
2014 |
Inestrosa NC, Varela-Nallar L. Wnt signaling in the nervous system and in Alzheimer's disease. Journal of Molecular Cell Biology. 6: 64-74. PMID 24549157 DOI: 10.1093/jmcb/mjt051 |
0.226 |
|
2021 |
Godoy JA, Espinoza-Caicedo J, Inestrosa NC. Morphological neurite changes induced by porcupine inhibition are rescued by Wnt ligands. Cell Communication and Signaling : Ccs. 19: 87. PMID 34399774 DOI: 10.1186/s12964-021-00709-y |
0.225 |
|
2010 |
FarÃas GG, Godoy JA, Cerpa W, Varela-Nallar L, Inestrosa NC. Wnt signaling modulates pre- and postsynaptic maturation: therapeutic considerations. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 239: 94-101. PMID 19681159 DOI: 10.1002/Dvdy.22065 |
0.223 |
|
2018 |
Ramos-Fernández E, Tapia-Rojas C, Ramírez VT, Inestrosa NC. Wnt-7a Stimulates Dendritic Spine Morphogenesis and PSD-95 Expression Through Canonical Signaling. Molecular Neurobiology. PMID 29967987 DOI: 10.1007/s12035-018-1162-1 |
0.223 |
|
2021 |
Martínez M, Inestrosa NC. The transcriptional landscape of Alzheimer's disease and its association with Wnt signaling pathway. Neuroscience and Biobehavioral Reviews. PMID 34224789 DOI: 10.1016/j.neubiorev.2021.06.029 |
0.221 |
|
2021 |
Torres VI, Barrera DP, Varas-Godoy M, Arancibia D, Inestrosa NC. Selective Surface and Intraluminal Localization of Wnt Ligands on Small Extracellular Vesicles Released by HT-22 Hippocampal Neurons. Frontiers in Cell and Developmental Biology. 9: 735888. PMID 34722516 DOI: 10.3389/fcell.2021.735888 |
0.22 |
|
2012 |
Inestrosa NC, Montecinos-Oliva C, Fuenzalida M. Wnt signaling: role in Alzheimer disease and schizophrenia. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 7: 788-807. PMID 23160851 DOI: 10.1007/s11481-012-9417-5 |
0.217 |
|
2020 |
Inestrosa NC, Tapia-Rojas C, Lindsay CB, Zolezzi JM. Wnt Signaling Pathway Dysregulation in the Aging Brain: Lessons From the . Frontiers in Cell and Developmental Biology. 8: 734. PMID 32850846 DOI: 10.3389/fcell.2020.00734 |
0.217 |
|
2020 |
Lira M, Mira RG, Carvajal FJ, Zamorano P, Inestrosa NC, Cerpa W. Glutamatergic Receptor Trafficking and Delivery: Role of the Exocyst Complex. Cells. 9. PMID 33153008 DOI: 10.3390/cells9112402 |
0.217 |
|
2012 |
Cabeza C, Figueroa A, Lazo OM, Galleguillos C, Pissani C, Klein A, Gonzalez-Billault C, Inestrosa NC, Alvarez AR, Zanlungo S, Bronfman FC. Cholinergic abnormalities, endosomal alterations and up-regulation of nerve growth factor signaling in Niemann-Pick type C disease. Molecular Neurodegeneration. 7: 11. PMID 22458984 DOI: 10.1186/1750-1326-7-11 |
0.214 |
|
2009 |
Arrázola MS, Varela-Nallar L, Colombres M, Toledo EM, Cruzat F, Pavez L, Assar R, Aravena A, González M, Montecino M, Maass A, MartÃnez S, Inestrosa NC. Calcium/calmodulin-dependent protein kinase type IV is a target gene of the Wnt/beta-catenin signaling pathway. Journal of Cellular Physiology. 221: 658-67. PMID 19711354 DOI: 10.1002/Jcp.21902 |
0.212 |
|
2013 |
Silva-Alvarez C, Arrázola MS, Godoy JA, Ordenes D, Inestrosa NC. Canonical Wnt signaling protects hippocampal neurons from Aβ oligomers: role of non-canonical Wnt-5a/Ca(2+) in mitochondrial dynamics. Frontiers in Cellular Neuroscience. 7: 97. PMID 23805073 DOI: 10.3389/fncel.2013.00097 |
0.212 |
|
1998 |
Calderón FH, von Bernhardi R, De Ferrari G, Luza S, Aldunate R, Inestrosa NC. Toxic effects of acetylcholinesterase on neuronal and glial-like cells in vitro. Molecular Psychiatry. 3: 247-55. PMID 9672900 DOI: 10.1038/sj.mp.4000383 |
0.211 |
|
2010 |
Perez de Arce K, de Arce KP, Varela-Nallar L, Farias O, Cifuentes A, Bull P, Couch BA, Koleske AJ, Inestrosa NC, Alvarez AR. Synaptic clustering of PSD-95 is regulated by c-Abl through tyrosine phosphorylation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 3728-38. PMID 20220006 DOI: 10.1523/Jneurosci.2024-09.2010 |
0.211 |
|
2015 |
Oliva CA, Inestrosa NC. A novel function for Wnt signaling modulating neuronal firing activity and the temporal structure of spontaneous oscillation in the entorhinal-hippocampal circuit. Experimental Neurology. 269: 43-55. PMID 25857536 DOI: 10.1016/j.expneurol.2015.03.027 |
0.211 |
|
1981 |
Méndez B, Inestrosa NC. Acetylcholinesterase aggregates in a newly formed motor nerve-smooth muscle junction. Brain Research Bulletin. 7: 17-24. PMID 7272784 DOI: 10.1016/0361-9230(81)90093-9 |
0.21 |
|
2019 |
Bastías-Candia S, Martínez M, Zolezzi JM, Inestrosa NC. Wnt Signaling Upregulates Teneurin-3 Expression via Canonical and Non-canonical Wnt Pathway Crosstalk. Frontiers in Neuroscience. 13: 505. PMID 31156379 DOI: 10.3389/fnins.2019.00505 |
0.207 |
|
2013 |
Varela-Nallar L, Inestrosa NC. Wnt signaling in the regulation of adult hippocampal neurogenesis. Frontiers in Cellular Neuroscience. 7: 100. PMID 23805076 DOI: 10.3389/fncel.2013.00100 |
0.207 |
|
2014 |
Serrano FG, Tapia-Rojas C, Carvajal FJ, Hancke J, Cerpa W, Inestrosa NC. Andrographolide reduces cognitive impairment in young and mature AβPPswe/PS-1 mice. Molecular Neurodegeneration. 9: 61. PMID 25524173 DOI: 10.1186/1750-1326-9-61 |
0.206 |
|
2007 |
Inestrosa NC, Varela-Nallar L, Grabowski CP, Colombres M. Synaptotoxicity in Alzheimer's disease: The Wnt signaling pathway as a molecular target Iubmb Life. 59: 316-321. PMID 17505971 DOI: 10.1080/15216540701242490 |
0.206 |
|
1996 |
Bronfman FC, Fernandez HL, Inestrosa NC. Amyloid precursor protein fragment and acetylcholinesterase increase with cell confluence and differentiation in a neuronal cell line. Experimental Cell Research. 229: 93-9. PMID 8940253 DOI: 10.1006/Excr.1996.0347 |
0.204 |
|
1984 |
Inestrosa NC. 16S acetylcholinesterase of the extracellular matrix is assembled within mouse muscle cells in culture. The Biochemical Journal. 217: 377-81. PMID 6696736 DOI: 10.1042/bj2170377 |
0.204 |
|
1985 |
Torres JC, Inestrosa NC. Interaction of heparin with multimolecular aggregates of acetylcholinesterase. Cellular and Molecular Neurobiology. 5: 303-9. PMID 4064078 DOI: 10.1007/BF00711015 |
0.203 |
|
2017 |
Braidy N, Poljak A, Marjo C, Rutlidge H, Rich A, Inestrosa N, Sachdev PS. Identification Of Cerebral Metal Ion Imbalance In The Brain Of Ageing Octodon Degus: A Natural Model For Alzheimer'S Disease Alzheimers & Dementia. 13. DOI: 10.1016/J.Jalz.2017.06.729 |
0.203 |
|
2019 |
Arredondo SB, Guerrero FG, Herrera-Soto A, Jensen-Flores J, Bustamante DB, Oñate-Ponce A, Henny P, Varas-Godoy M, Inestrosa NC, Varela-Nallar L. Wnt5a promotes differentiation and development of adult-born neurons in the hippocampus by noncanonical Wnt signaling. Stem Cells (Dayton, Ohio). PMID 31721364 DOI: 10.1002/Stem.3121 |
0.2 |
|
2014 |
Cisternas P, Vio CP, Inestrosa NC. Role of Wnt signaling in tissue fibrosis, lessons from skeletal muscle and kidney. Current Molecular Medicine. 14: 510-22. PMID 24730522 DOI: 10.2174/1566524014666140414210346 |
0.199 |
|
2012 |
Codocedo JF, Allard C, Godoy JA, Varela-Nallar L, Inestrosa NC. SIRT1 regulates dendritic development in hippocampal neurons. Plos One. 7: e47073. PMID 23056585 DOI: 10.1371/journal.pone.0047073 |
0.198 |
|
2005 |
Inestrosa NC, Sagal JP, Colombres M. Acetylcholinesterase interaction with Alzheimer amyloid beta Sub-Cellular Biochemistry. 38: 299-317. PMID 15709485 |
0.197 |
|
2003 |
Chacón MA, Reyes AE, Inestrosa NC. Acetylcholinesterase induces neuronal cell loss, astrocyte hypertrophy and behavioral deficits in mammalian hippocampus. Journal of Neurochemistry. 87: 195-204. PMID 12969266 DOI: 10.1046/j.1471-4159.2003.01985.x |
0.196 |
|
1986 |
Inestrosa NC, Ruiz G. Membrane-bound form of acetylcholinesterase activated during postnatal development of the rat somatosensory cortex. Developmental Neuroscience. 7: 120-32. PMID 2415318 DOI: 10.1159/000112282 |
0.196 |
|
2019 |
Arancibia D, Lira M, Cruz Y, Barrera DP, Montenegro-Venegas C, Godoy JA, Garner CC, Inestrosa NC, Gundelfinger ED, Zamorano P, Torres VI. Serine-Arginine Protein Kinase SRPK2 Modulates the Assembly of the Active Zone Scaffolding Protein CAST1/ERC2. Cells. 8. PMID 31671734 DOI: 10.3390/cells8111333 |
0.196 |
|
1999 |
Muñoz FJ, Aldunate R, Inestrosa NC. Peripheral binding site is involved in the neurotrophic activity of acetylcholinesterase Neuroreport. 10: 3621-3625. PMID 10619655 |
0.196 |
|
2005 |
Cuitino L, Matute R, Retamal C, Bu G, Inestrosa NC, Marzolo MP. ApoER2 is endocytosed by a clathrin-mediated process involving the adaptor protein Dab2 independent of its Rafts' association. Traffic (Copenhagen, Denmark). 6: 820-38. PMID 16101684 DOI: 10.1111/J.1600-0854.2005.00320.X |
0.195 |
|
2010 |
Lazo OM, Mauna JC, Pissani CA, Inestrosa NC, Bronfman FC. Axotomy-induced neurotrophic withdrawal causes the loss of phenotypic differentiation and downregulation of NGF signalling, but not death of septal cholinergic neurons. Molecular Neurodegeneration. 5: 5. PMID 20205865 DOI: 10.1186/1750-1326-5-5 |
0.195 |
|
1988 |
Inestrosa NC, Fuentes ME, Anglister L, Futerman AH, Silman I. A membrane-associated dimer of acetylcholinesterase from Xenopus skeletal muscle is solubilized by phosphatidylinositol-specific phospholipase C. Neuroscience Letters. 90: 186-90. PMID 3412641 DOI: 10.1016/0304-3940(88)90809-9 |
0.194 |
|
2004 |
Alvarez AR, Godoy JA, Mullendorff K, Olivares GH, Bronfman M, Inestrosa NC. Wnt-3a overcomes beta-amyloid toxicity in rat hippocampal neurons. Experimental Cell Research. 297: 186-96. PMID 15194435 DOI: 10.1016/j.yexcr.2004.02.028 |
0.194 |
|
2016 |
Mardones MD, Andaur GA, Varas-Godoy M, Henriquez JF, Salech F, Behrens MI, Couve A, Inestrosa NC, Varela-Nallar L. Frizzled-1 receptor regulates adult hippocampal neurogenesis. Molecular Brain. 9: 29. PMID 26980182 DOI: 10.1186/s13041-016-0209-3 |
0.194 |
|
2013 |
Inestrosa NC, Carvajal FJ, Zolezzi JM, Tapia-Rojas C, Serrano F, Karmelic D, Toledo EM, Toro A, Toro J, Santos MJ. Peroxisome proliferators reduce spatial memory impairment, synaptic failure, and neurodegeneration in brains of a double transgenic mice model of Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 33: 941-59. PMID 23109558 DOI: 10.3233/Jad-2012-120397 |
0.194 |
|
2020 |
Chang LY, Ardiles AO, Tapia-Rojas C, Araya J, Inestrosa NC, Palacios AG, Acosta ML. Evidence of Synaptic and Neurochemical Remodeling in the Retina of Aging Degus. Frontiers in Neuroscience. 14: 161. PMID 32256305 DOI: 10.3389/fnins.2020.00161 |
0.194 |
|
1998 |
De Ferrari GV, von Bernhardi R, Calderón FH, Luza SC, Inestrosa NC. Responses induced by tacrine in neuronal and non-neuronal cell lines. Journal of Neuroscience Research. 52: 435-44. PMID 9589388 DOI: 10.1002/(SICI)1097-4547(19980515)52:4<435::AID-JNR7>3.0.CO;2-A |
0.194 |
|
2015 |
Tapia-Rojas C, Schüller A, Lindsay CB, Ureta RC, MejÃas-Reyes C, Hancke J, Melo F, Inestrosa NC. Andrographolide activates the canonical Wnt signalling pathway by a mechanism that implicates the non-ATP competitive inhibition of GSK-3β: autoregulation of GSK-3β in vivo. The Biochemical Journal. 466: 415-30. PMID 25423492 DOI: 10.1042/BJ20140207 |
0.194 |
|
1991 |
Moya MA, Fuentes ME, Inestrosa NC. A comparison of the Xenopus laevis oocyte acetylcholinesterase with the muscle and brain enzyme suggests variations at the post-translational level. Comparative Biochemistry and Physiology. C, Comparative Pharmacology and Toxicology. 98: 299-305. PMID 1676945 DOI: 10.1016/0742-8413(91)90209-C |
0.193 |
|
2020 |
Montecinos-Oliva C, Arrázola MS, Jara C, Tapia-Rojas C, Inestrosa NC. Hormetic-Like Effects of L-Homocysteine on Synaptic Structure, Function, and Aβ Aggregation. Pharmaceuticals (Basel, Switzerland). 13. PMID 32024240 DOI: 10.3390/ph13020024 |
0.192 |
|
2015 |
Serrano FG, Tapia-Rojas C, Carvajal FJ, Cisternas P, Viayna E, Irene S, Muñoz-Torrero D, Inestrosa NC. Rhein-huprine derivatives reduce cognitive impairment, synaptic failure and amyloid pathology in AβPPswe/PS-1 mice of different ages. Current Alzheimer Research. PMID 26502813 |
0.191 |
|
1994 |
Inestrosa NC, Pérez CA, Simpfendorfer RW. Sensitivity of acetylcholinesterase molecular forms to inhibition by high MgCl2 concentration. Biochimica Et Biophysica Acta. 1208: 286-93. PMID 7947960 DOI: 10.1016/0167-4838(94)90115-5 |
0.191 |
|
2006 |
Inestrosa N. S4-03-04 Alzheimers & Dementia. 2. DOI: 10.1016/J.Jalz.2006.05.280 |
0.19 |
|
2014 |
Godoy JA, Arrázola MS, Ordenes D, Silva-Alvarez C, Braidy N, Inestrosa NC. Wnt-5a ligand modulates mitochondrial fission-fusion in rat hippocampal neurons. The Journal of Biological Chemistry. 289: 36179-93. PMID 25336659 DOI: 10.1074/jbc.M114.557009 |
0.19 |
|
2014 |
Godoy JA, Rios JA, Zolezzi JM, Braidy N, Inestrosa NC. Signaling pathway cross talk in Alzheimer's disease. Cell Communication and Signaling : Ccs. 12: 23. PMID 24679124 DOI: 10.1186/1478-811X-12-23 |
0.189 |
|
2010 |
Dinamarca MC, Sagal JP, Quintanilla RA, Godoy JA, Arrázola MS, Inestrosa NC. Amyloid-beta-Acetylcholinesterase complexes potentiate neurodegenerative changes induced by the Abeta peptide. Implications for the pathogenesis of Alzheimer's disease. Molecular Neurodegeneration. 5: 4. PMID 20205793 DOI: 10.1186/1750-1326-5-4 |
0.189 |
|
2013 |
Inestrosa NC, Godoy JA, Vargas JY, Arrazola MS, Rios JA, Carvajal FJ, Serrano FG, Farias GG. Nicotine prevents synaptic impairment induced by amyloid-β oligomers through α7-nicotinic acetylcholine receptor activation. Neuromolecular Medicine. 15: 549-69. PMID 23842742 DOI: 10.1007/s12017-013-8242-1 |
0.188 |
|
2007 |
FarÃas GG, Vallés AS, Colombres M, Godoy JA, Toledo EM, Lukas RJ, Barrantes FJ, Inestrosa NC. Wnt-7a induces presynaptic colocalization of alpha 7-nicotinic acetylcholine receptors and adenomatous polyposis coli in hippocampal neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 5313-25. PMID 17507554 DOI: 10.1523/Jneurosci.3934-06.2007 |
0.187 |
|
1989 |
Perelman A, Inestrosa NC. A simple assay to estimate the acetylcholinesterase molecular forms in crude extracts of rat skeletal muscle. Analytical Biochemistry. 180: 227-30. PMID 2817352 DOI: 10.1016/0003-2697(89)90421-1 |
0.187 |
|
2013 |
Codocedo JF, Godoy JA, Poblete MI, Inestrosa NC, Huidobro-Toro JP. ATP induces NO production in hippocampal neurons by P2X(7) receptor activation independent of glutamate signaling. Plos One. 8: e57626. PMID 23472093 DOI: 10.1371/journal.pone.0057626 |
0.187 |
|
2021 |
Friedli MJ, Inestrosa NC. Huperzine A and Its Neuroprotective Molecular Signaling in Alzheimer's Disease. Molecules (Basel, Switzerland). 26. PMID 34770940 DOI: 10.3390/molecules26216531 |
0.187 |
|
2019 |
Cisternas P, Oliva CA, Torres VI, Barrera DP, Inestrosa NC. Presymptomatic Treatment With Andrographolide Improves Brain Metabolic Markers and Cognitive Behavior in a Model of Early-Onset Alzheimer's Disease. Frontiers in Cellular Neuroscience. 13: 295. PMID 31379502 DOI: 10.3389/fncel.2019.00295 |
0.186 |
|
2017 |
Bignante EA, Ponce NE, Heredia F, Musso J, Krawczyk MC, Millán J, Pigino GF, Inestrosa NC, Boccia MM, Lorenzo A. APP/Go protein Gβγ-complex signaling mediates Aβ degeneration and cognitive impairment in Alzheimer's disease models. Neurobiology of Aging. 64: 44-57. PMID 29331876 DOI: 10.1016/J.Neurobiolaging.2017.12.013 |
0.186 |
|
2015 |
Cisternas P, Salazar P, Serrano FG, Montecinos-Oliva C, Arredondo SB, Varela-Nallar L, Barja S, Vio CP, Gomez-Pinilla F, Inestrosa NC. Fructose consumption reduces hippocampal synaptic plasticity underlying cognitive performance. Biochimica Et Biophysica Acta. 1852: 2379-90. PMID 26300486 DOI: 10.1016/J.Bbadis.2015.08.016 |
0.185 |
|
2018 |
Oliva CA, Montecinos-Oliva C, Inestrosa NC. Wnt Signaling in the Central Nervous System: New Insights in Health and Disease. Progress in Molecular Biology and Translational Science. 153: 81-130. PMID 29389523 DOI: 10.1016/bs.pmbts.2017.11.018 |
0.185 |
|
2000 |
De Ferrari and GV, Inestrosa NC. Wnt signaling function in Alzheimer's disease Brain Research Reviews. 33: 1-12. PMID 10967351 DOI: 10.1016/S0165-0173(00)00021-7 |
0.184 |
|
2015 |
Bastías-Candia S, Braidy N, Zolezzi JM, Inestrosa NC. Teneurins and Alzheimer's disease: a suggestive role for a unique family of proteins. Medical Hypotheses. 84: 402-7. PMID 25665860 DOI: 10.1016/j.mehy.2015.01.026 |
0.184 |
|
2007 |
Fuenzalida K, Quintanilla R, Ramos P, Piderit D, Fuentealba RA, Martinez G, Inestrosa NC, Bronfman M. Peroxisome proliferator-activated receptor gamma up-regulates the Bcl-2 anti-apoptotic protein in neurons and induces mitochondrial stabilization and protection against oxidative stress and apoptosis. The Journal of Biological Chemistry. 282: 37006-15. PMID 17965419 DOI: 10.1074/Jbc.M700447200 |
0.182 |
|
1984 |
Maldonado M, Ramírez BU, Ruiz G, Yamuy J, Inestrosa NC. Age-related responses of skeletal muscle after ectopic innervation, with particular reference to 16S acetylcholinesterase, in adult rats. Journal of Neurochemistry. 43: 375-81. PMID 6736957 DOI: 10.1111/j.1471-4159.1984.tb00911.x |
0.182 |
|
1992 |
Fuentes ME, Inestrosa NC. Amphiphilic behavior of a brain tetrameric acetylcholinesterase form lacking the plasma membrane anchoring domain. Brain Research. 580: 1-5. PMID 1504788 DOI: 10.1016/0006-8993(92)90919-Z |
0.182 |
|
2013 |
Slater PG, Ramirez VT, Gonzalez-Billault C, Varela-Nallar L, Inestrosa NC. Frizzled-5 receptor is involved in neuronal polarity and morphogenesis of hippocampal neurons. Plos One. 8: e78892. PMID 24205342 DOI: 10.1371/Journal.Pone.0078892 |
0.181 |
|
2003 |
Von Bernhardi R, Ramírez G, De Ferrari GV, Inestrosa NC. Acetylcholinesterase induces the expression of the β-amyloid precursor protein in glia and activates glial cells in culture Neurobiology of Disease. 14: 447-457. PMID 14678761 DOI: 10.1016/j.nbd.2003.08.014 |
0.181 |
|
2019 |
Pardo E, Barake F, Godoy JA, Oyanadel C, Espinoza S, Metz C, Retamal C, Massardo L, Tapia-Rojas C, Inestrosa NC, Soza A, González A. GALECTIN-8 Is a Neuroprotective Factor in the Brain that Can Be Neutralized by Human Autoantibodies. Molecular Neurobiology. PMID 31119556 DOI: 10.1007/s12035-019-1621-3 |
0.181 |
|
2000 |
Marzolo MP, Von Bernhardi R, Bu G, Inestrosa NC. Expression of α2-macroglobulin receptor/low density lipoprotein receptor-related protein (LRP) in rat microglial cells Journal of Neuroscience Research. 60: 401-411. PMID 10797543 DOI: 10.1002/(Sici)1097-4547(20000501)60:3<401::Aid-Jnr15>3.0.Co;2-L |
0.18 |
|
2006 |
Varela-Nallar L, Toledo EM, Larrondo LF, Cabral ALB, Martins VR, Inestrosa NC. Induction of cellular prion protein gene expression by copper in neurons American Journal of Physiology - Cell Physiology. 290: C271-C281. PMID 16148034 DOI: 10.1152/Ajpcell.00160.2005 |
0.18 |
|
2011 |
Inestrosa NC, Tapia-Rojas C, Griffith TN, Carvajal FJ, Benito MJ, Rivera-Dictter A, Alvarez AR, Serrano FG, Hancke JL, Burgos PV, Parodi J, Varela-Nallar L. Tetrahydrohyperforin prevents cognitive deficit, Aβ deposition, tau phosphorylation and synaptotoxicity in the APPswe/PSEN1ΔE9 model of Alzheimer's disease: a possible effect on APP processing. Translational Psychiatry. 1: e20. PMID 22832522 DOI: 10.1038/tp.2011.19 |
0.18 |
|
2016 |
Cisternas P, Salazar P, Silva-Alvarez C, Barros LF, Inestrosa NC. Activation of Wnt signaling in cortical neurons enhances glucose utilization through glycolysis. The Journal of Biological Chemistry. PMID 27703002 DOI: 10.1074/jbc.M116.735373 |
0.179 |
|
2014 |
Viayna E, Sola I, Bartolini M, De Simone A, Tapia-Rojas C, Serrano FG, Sabaté R, Juárez-Jiménez J, Pérez B, Luque FJ, Andrisano V, Clos MV, Inestrosa NC, Muñoz-Torrero D. Synthesis and multitarget biological profiling of a novel family of rhein derivatives as disease-modifying anti-Alzheimer agents. Journal of Medicinal Chemistry. 57: 2549-67. PMID 24568372 DOI: 10.1021/Jm401824W |
0.179 |
|
1995 |
Deprez PN, Signorelli J, Inestrosa NC. Effect of protamine on the solubilization of collagen-tailed acetylcholinesterase: potential heparin-binding consensus sequences in the tail of the enzyme. Biochimica Et Biophysica Acta. 1252: 53-8. PMID 7548166 DOI: 10.1016/0167-4838(95)00109-8 |
0.179 |
|
2005 |
Inestrosa NC, Godoy JA, Quintanilla RA, Koenig CS, Bronfman M. Peroxisome proliferator-activated receptor γ is expressed in hippocampal neurons and its activation prevents β-amyloid neurodegeneration: Role of Wnt signaling Experimental Cell Research. 304: 91-104. PMID 15707577 DOI: 10.1016/j.yexcr.2004.09.032 |
0.177 |
|
2004 |
Inestrosa NC, Urra S, Colombres M. Acetylcholinesterase (AChE)--amyloid-beta-peptide complexes in Alzheimer's disease. the Wnt signaling pathway Curr Alzheimer Res. 1: 249-254. PMID 15975054 |
0.177 |
|
2015 |
Tapia-Rojas C, Lindsay CB, Montecinos-Oliva C, Arrazola MS, Retamales RM, Bunout D, Hirsch S, Inestrosa NC. Is L-methionine a trigger factor for Alzheimer's-like neurodegeneration?: Changes in Aβ oligomers, tau phosphorylation, synaptic proteins, Wnt signaling and behavioral impairment in wild-type mice. Molecular Neurodegeneration. 10: 62. PMID 26590557 DOI: 10.1186/s13024-015-0057-0 |
0.177 |
|
2016 |
Codocedo JF, Inestrosa NC. Wnt-5a-regulated miR-101b controls COX2 expression in hippocampal neurons. Biological Research. 49: 9. PMID 26895946 DOI: 10.1186/s40659-016-0071-x |
0.176 |
|
2013 |
Carvajal FJ, Zolezzi JM, Tapia-Rojas C, Godoy JA, Inestrosa NC. Tetrahydrohyperforin decreases cholinergic markers associated with amyloid-β plaques, 4-hydroxynonenal formation, and caspase-3 activation in AβPP/PS1 mice. Journal of Alzheimer's Disease : Jad. 36: 99-118. PMID 23568104 DOI: 10.3233/JAD-130230 |
0.176 |
|
2013 |
Abbott AC, Calderon Toledo C, Aranguiz FC, Inestrosa NC, Varela-Nallar L. Tetrahydrohyperforin increases adult hippocampal neurogenesis in wild-type and APPswe/PS1ΔE9 mice. Journal of Alzheimer's Disease : Jad. 34: 873-85. PMID 23302657 DOI: 10.3233/JAD-121714 |
0.176 |
|
2015 |
Cisternas P, Salazar P, Serrano FG, Montecinos-Oliva C, Arredondo SB, Varela-Nallar L, Barja S, Vio CP, Gomez-Pinilla F, Inestrosa NC. Fructose consumption reduces hippocampal synaptic plasticity underlying cognitive performance Biochimica Et Biophysica Acta - Molecular Basis of Disease. 1852: 2379-2390. DOI: 10.1016/j.bbadis.2015.08.016 |
0.176 |
|
2019 |
Torres VI, Godoy JA, Inestrosa NC. Modulating Wnt signaling at the root: Porcupine and Wnt acylation. Pharmacology & Therapeutics. PMID 30790642 DOI: 10.1016/j.pharmthera.2019.02.009 |
0.176 |
|
2008 |
Toledo EM, Colombres M, Inestrosa NC. Wnt signaling in neuroprotection and stem cell differentiation. Progress in Neurobiology. 86: 281-96. PMID 18786602 DOI: 10.1016/J.Pneurobio.2008.08.001 |
0.176 |
|
2008 |
Chacón MA, Varela-Nallar L, Inestrosa NC. Frizzled-1 is involved in the neuroprotective effect of Wnt3a against Abeta oligomers. Journal of Cellular Physiology. 217: 215-27. PMID 18521822 DOI: 10.1002/jcp.21497 |
0.176 |
|
1977 |
Inestrosa NC, Fernandez HL. Muscle enzymatic changes induced by blockage of axoplasmic transport. Journal of Neurophysiology. 39: 1236-45. PMID 62830 DOI: 10.1152/jn.1976.39.6.1236 |
0.175 |
|
2008 |
Inestrosa NC, Toledo EM. The role of Wnt signaling in neuronal dysfunction in Alzheimer's Disease. Molecular Neurodegeneration. 3: 9. PMID 18652670 DOI: 10.1186/1750-1326-3-9 |
0.174 |
|
2021 |
Torres AK, Jara C, Park-Kang HS, Polanco CM, Tapia D, Alarcón F, de la Peña A, Llanquinao J, Vargas-Mardones G, Indo JA, Inestrosa NC, Tapia-Rojas C. Synaptic Mitochondria: An Early Target of Amyloid-β and Tau in Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. 84: 1391-1414. PMID 34719499 DOI: 10.3233/JAD-215139 |
0.174 |
|
2015 |
Varela-Nallar L, Arredondo SB, Tapia-Rojas C, Hancke J, Inestrosa NC. Andrographolide Stimulates Neurogenesis in the Adult Hippocampus. Neural Plasticity. 2015: 935403. PMID 26798521 DOI: 10.1155/2015/935403 |
0.174 |
|
2017 |
Arrázola MS, Ramos-Fernández E, Cisternas P, Ordenes D, Inestrosa NC. Wnt Signaling Prevents the Aβ Oligomer-Induced Mitochondrial Permeability Transition Pore Opening Preserving Mitochondrial Structure in Hippocampal Neurons. Plos One. 12: e0168840. PMID 28060833 DOI: 10.1371/journal.pone.0168840 |
0.173 |
|
2010 |
Toledo EM, Inestrosa NC. Activation of Wnt signaling by lithium and rosiglitazone reduced spatial memory impairment and neurodegeneration in brains of an APPswe/PSEN1DeltaE9 mouse model of Alzheimer's disease. Molecular Psychiatry. 15: 272-85, 228. PMID 19621015 DOI: 10.1038/Mp.2009.72 |
0.173 |
|
1983 |
Torres JC, Behrens MI, Inestrosa NC. Neural 16S acetylcholinesterase is solubilized by heparin. The Biochemical Journal. 215: 201-4. PMID 6626175 DOI: 10.1042/bj2150201 |
0.172 |
|
1989 |
Fadić R, Inestrosa NC. Nerve regulation of class I and class II-asymmetric forms of acetylcholinesterase in rat skeletal muscles. Journal of Neuroscience Research. 22: 449-55. PMID 2760943 DOI: 10.1002/jnr.490220410 |
0.172 |
|
2014 |
Braidy N, Brew BJ, Inestrosa NC, Chung R, Sachdev P, Guillemin GJ. Changes in Cathepsin D and Beclin-1 mRNA and protein expression by the excitotoxin quinolinic acid in human astrocytes and neurons. Metabolic Brain Disease. 29: 873-83. PMID 24833554 DOI: 10.1007/S11011-014-9557-9 |
0.171 |
|
2014 |
Varela-Nallar L, Rojas-Abalos M, Abbott AC, Moya EA, Iturriaga R, Inestrosa NC. Chronic hypoxia induces the activation of the Wnt/β-catenin signaling pathway and stimulates hippocampal neurogenesis in wild-type and APPswe-PS1ΔE9 transgenic mice in vivo. Frontiers in Cellular Neuroscience. 8: 17. PMID 24574965 DOI: 10.3389/fncel.2014.00017 |
0.17 |
|
2017 |
Tapia-Rojas C, Inestrosa NC. Wnt signaling loss accelerates the appearance of neuropathological hallmarks of Alzheimer's disease in J20-APP transgenic and wild-type mice. Journal of Neurochemistry. PMID 29240990 DOI: 10.1111/jnc.14278 |
0.17 |
|
2017 |
Bustos FJ, Ampuero E, Jury N, Aguilar R, Falahi F, Toledo J, Ahumada J, Lata J, Cubillos P, Henríquez B, Guerra MV, Stehberg J, Neve RL, Inestrosa NC, Wyneken U, et al. Epigenetic editing of the Dlg4/PSD95 gene improves cognition in aged and Alzheimer's disease mice. Brain : a Journal of Neurology. PMID 29155979 DOI: 10.1093/Brain/Awx272 |
0.17 |
|
2005 |
Farías GG, Godoy JA, Vázquez MC, Adani R, Meshulam H, Avila J, Amitai G, Inestrosa NC. The anti-inflammatory and cholinesterase inhibitor bifunctional compound IBU-PO protects from β-amyloid neurotoxicity by acting on Wnt signaling components Neurobiology of Disease. 18: 176-183. PMID 15649708 DOI: 10.1016/j.nbd.2004.09.012 |
0.17 |
|
2015 |
Arrázola MS, Silva-Alvarez C, Inestrosa NC. How the Wnt signaling pathway protects from neurodegeneration: the mitochondrial scenario. Frontiers in Cellular Neuroscience. 9: 166. PMID 25999816 DOI: 10.3389/fncel.2015.00166 |
0.169 |
|
1999 |
Calderón FH, Bonnefont A, Muñoz FJ, Fernández V, Videla LA, Inestrosa NC. PC12 and neuro 2a cells have different susceptibilities to acetylcholinesterase-amyloid complexes, amyloid25-35 fragment, glutamate, and hydrogen peroxide. Journal of Neuroscience Research. 56: 620-31. PMID 10374817 DOI: 10.1002/(SICI)1097-4547(19990615)56:6<620::AID-JNR8>3.0.CO;2-F |
0.168 |
|
2008 |
Cerpa W, Dinamarca MC, Inestrosa NC. Structure-function implications in Alzheimer's disease: effect of Abeta oligomers at central synapses. Current Alzheimer Research. 5: 233-43. PMID 18537540 DOI: 10.2174/156720508784533321 |
0.168 |
|
1999 |
Marzolo MP, Von Bernhardi R, Inestrosa NC. Mannose receptor is present in a functional state in rat microglial cells Journal of Neuroscience Research. 58: 387-395. PMID 10518112 DOI: 10.1002/(SICI)1097-4547(19991101)58:3<387::AID-JNR4>3.0.CO;2-L |
0.166 |
|
2018 |
Salazar P, Cisternas P, Martinez M, Inestrosa NC. Hypothyroidism and Cognitive Disorders during Development and Adulthood: Implications in the Central Nervous System. Molecular Neurobiology. PMID 30073507 DOI: 10.1007/s12035-018-1270-y |
0.166 |
|
2004 |
Farías GG, Godoy JA, Hernández F, Avila J, Fisher A, Inestrosa NC. M1 muscarinic receptor activation protects neurons from β-amyloid toxicity. A role for Wnt signaling pathway Neurobiology of Disease. 17: 337-348. PMID 15474371 DOI: 10.1016/j.nbd.2004.07.016 |
0.166 |
|
1983 |
Behrens MI, Soza MA, Inestrosa NC. Increase of muscle peroxisomal enzymes and myotonia induced by nafenopin, a hypolipidemic drug. Muscle & Nerve. 6: 154-9. PMID 6855799 DOI: 10.1002/mus.880060212 |
0.166 |
|
2016 |
Godoy JA, Lindsay CB, Quintanilla RA, Carvajal FJ, Cerpa W, Inestrosa NC. Quercetin Exerts Differential Neuroprotective Effects Against H2O2 and Aβ Aggregates in Hippocampal Neurons: the Role of Mitochondria. Molecular Neurobiology. PMID 27796749 DOI: 10.1007/S12035-016-0203-X |
0.165 |
|
1989 |
Inestrosa NC, Perelman A. Distribution and anchoring of molecular forms of acetylcholinesterase. Trends in Pharmacological Sciences. 10: 325-9. PMID 2686130 DOI: 10.1016/0165-6147(89)90067-9 |
0.164 |
|
2011 |
Carvajal FJ, Inestrosa NC. Interactions of AChE with Aβ Aggregates in Alzheimer's Brain: Therapeutic Relevance of IDN 5706. Frontiers in Molecular Neuroscience. 4: 19. PMID 21949501 DOI: 10.3389/fnmol.2011.00019 |
0.164 |
|
2002 |
Garrido JL, Godoy JA, Alvarez A, Bronfman M, Inestrosa NC. Protein kinase C inhibits amyloid beta peptide neurotoxicity by acting on members of the Wnt pathway The Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 16: 1982-1984. PMID 12397090 |
0.163 |
|
2003 |
Deprez P, Inestrosa NC, Krejci E. Two different heparin-binding domains in the triple-helical domain of ColQ, the collagen tail subunit of synaptic acetylcholinesterase Journal of Biological Chemistry. 278: 23233-23242. PMID 12684510 DOI: 10.1074/jbc.M301384200 |
0.162 |
|
2015 |
Cavieres VA, González A, Muñoz VC, Yefi CP, Bustamante HA, Barraza RR, Tapia-Rojas C, Otth C, Barrera MJ, González C, Mardones GA, Inestrosa NC, Burgos PV. Tetrahydrohyperforin Inhibits the Proteolytic Processing of Amyloid Precursor Protein and Enhances Its Degradation by Atg5-Dependent Autophagy. Plos One. 10: e0136313. PMID 26308941 DOI: 10.1371/journal.pone.0136313 |
0.162 |
|
2008 |
Inestrosa NC, Chacon M, Barria MI, Varela-Nallar L, Opazo C. Neuroprotective properties of copper binding fragments of amyloid precursor protein and prion Journal of Neurochemistry. 81: 80-80. DOI: 10.1046/J.1471-4159.81.S1.103.X |
0.162 |
|
2003 |
De Ferrari GV, Chacón MA, BarrÃa MI, Garrido JL, Godoy JA, Olivares G, Reyes AE, Alvarez A, Bronfman M, Inestrosa NC. Activation of Wnt signaling rescues neurodegeneration and behavioral impairments induced by beta-amyloid fibrils. Molecular Psychiatry. 8: 195-208. PMID 12610652 DOI: 10.1038/sj.mp.4001208 |
0.162 |
|
1996 |
Bronfman FC, Soto C, Tapia L, Tapia V, Inestrosa NC. Extracellular matrix regulates the amount of the beta-amyloid precursor protein and its amyloidogenic fragments. Journal of Cellular Physiology. 166: 360-9. PMID 8591996 DOI: 10.1002/(Sici)1097-4652(199602)166:2<360::Aid-Jcp14>3.0.Co;2-F |
0.162 |
|
2005 |
Santos MJ, Quintanilla RA, Toro A, Grandy R, Dinamarca MC, Godoy JA, Inestrosa NC. Peroxisomal proliferation protects from beta-amyloid neurodegeneration. The Journal of Biological Chemistry. 280: 41057-68. PMID 16204253 DOI: 10.1074/jbc.M505160200 |
0.161 |
|
2017 |
Zolezzi JM, Santos MJ, Bastías-Candia S, Pinto C, Godoy JA, Inestrosa NC. PPARs in the central nervous system: roles in neurodegeneration and neuroinflammation. Biological Reviews of the Cambridge Philosophical Society. PMID 28220655 DOI: 10.1111/brv.12320 |
0.161 |
|
2018 |
Rivera DS, Lindsay CB, Codocedo JF, Carreño LE, Cabrera D, Arrese MA, Vio CP, Bozinovic F, Inestrosa NC. Long-Term, Fructose-Induced Metabolic Syndrome-Like Condition Is Associated with Higher Metabolism, Reduced Synaptic Plasticity and Cognitive Impairment in Octodon degus. Molecular Neurobiology. PMID 29654490 DOI: 10.1007/s12035-018-0969-0 |
0.16 |
|
2017 |
Godoy JA, Zolezzi JM, Inestrosa NC. INT131 increases dendritic arborization and protects against Aβ toxicity by inducing mitochondrial changes in hippocampal neurons. Biochemical and Biophysical Research Communications. PMID 28655613 DOI: 10.1016/j.bbrc.2017.06.146 |
0.16 |
|
2010 |
Parodi J, Sepúlveda FJ, Roa J, Opazo C, Inestrosa NC, Aguayo LG. Beta-amyloid causes depletion of synaptic vesicles leading to neurotransmission failure. The Journal of Biological Chemistry. 285: 2506-14. PMID 19915004 DOI: 10.1074/jbc.M109.030023 |
0.159 |
|
1995 |
Alvarez J, Moreno RD, Inestrosa NC. Mitosis of Schwann cells and demyelination are induced by the amyloid precursor protein and other protease inhibitors in the rat sciatic nerve. The European Journal of Neuroscience. 7: 152-9. PMID 7536093 DOI: 10.1111/j.1460-9568.1995.tb01029.x |
0.156 |
|
2018 |
Ríos JA, Godoy JA, Inestrosa NC. Wnt3a ligand facilitates autophagy in hippocampal neurons by modulating a novel GSK-3β-AMPK axis. Cell Communication and Signaling : Ccs. 16: 15. PMID 29642895 DOI: 10.1186/s12964-018-0227-0 |
0.155 |
|
1997 |
Reyes AE, Perez DR, Alvarez A, Garrido J, Gentry MK, Doctor BP, Inestrosa NC. A monoclonal antibody against acetylcholinesterase inhibits the formation of amyloid fibrils induced by the enzyme Biochemical and Biophysical Research Communications. 232: 652-655. PMID 9126330 DOI: 10.1006/bbrc.1997.6357 |
0.154 |
|
2016 |
Guivernau B, Bonet J, Valls-Comamala V, Bosch-Morató M, Godoy JA, Inestrosa NC, Perálvarez-Marín A, Fernández-Busquets X, Andreu D, Oliva B, Muñoz FJ. Amyloid-β Peptide Nitrotyrosination Stabilizes Oligomers and Enhances NMDAR-Mediated Toxicity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 11693-11703. PMID 27852777 DOI: 10.1523/Jneurosci.1081-16.2016 |
0.153 |
|
2005 |
Inestrosa NC, Alvarez A, Dinamarca MC, Pérez-Acle T, Colombres M. Acetylcholinesterase-amyloid-β-peptide interaction: Effect of Congo Red and the role of the Wnt pathway Current Alzheimer Research. 2: 301-306. PMID 15974895 DOI: 10.2174/1567205054367928 |
0.153 |
|
2017 |
Salech F, Varela-Nallar L, Arredondo SB, Bustamante DB, Andaur GA, Cisneros R, Ponce DP, Ayala P, Inestrosa NC, Valdés JL, Behrens MI, Couve A. Local Klotho enhances neuronal progenitor proliferation in the adult hippocampus. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. PMID 29300914 DOI: 10.1093/Gerona/Glx248 |
0.153 |
|
1996 |
Fernandez HL, Moreno RD, Inestrosa NC. Tetrameric (G4) acetylcholinesterase: structure, localization, and physiological regulation. Journal of Neurochemistry. 66: 1335-46. PMID 8627284 DOI: 10.1046/j.1471-4159.1996.66041335.x |
0.152 |
|
1998 |
Moreno RD, Campos FO, Dajas F, Inestrosa NC. Developmental regulation of mouse brain monomeric acetylcholinesterase. International Journal of Developmental Neuroscience : the Official Journal of the International Society For Developmental Neuroscience. 16: 123-34. PMID 9762585 DOI: 10.1016/S0736-5748(98)00008-2 |
0.152 |
|
2016 |
Cisternas P, Salazar P, Silva-Álvarez C, Barros LF, Inestrosa NC. Wnt5a Increases the Glycolytic Rate and the Activity of the Pentose Phosphate Pathway in Cortical Neurons. Neural Plasticity. 2016: 9839348. PMID 27688915 DOI: 10.1155/2016/9839348 |
0.152 |
|
2004 |
Fuentealba RA, Farias G, Scheu J, Bronfman M, Marzolo MP, Inestrosa NC. Signal transduction during amyloid-β-peptide neurotoxicity: Role in Alzheimer disease Brain Research Reviews. 47: 275-289. PMID 15572177 DOI: 10.1016/J.Brainresrev.2004.07.018 |
0.152 |
|
2017 |
Salazar P, Cisternas P, Codocedo JF, Inestrosa NC. Induction of hypothyroidism during early postnatal stages triggers a decrease in cognitive performance by decreasing hippocampal synaptic plasticity. Biochimica Et Biophysica Acta. PMID 28088629 DOI: 10.1016/j.bbadis.2017.01.002 |
0.151 |
|
2000 |
Inestrosa NC, Alvarez A, Godoy J, Reyes A, De Ferrari GV. Acetylcholinesterase-amyloid-β-peptide interaction and Wnt signaling involvement in Aβ neurotoxicity Acta Neurologica Scandinavica, Supplement. 102: 53-59. PMID 11261806 |
0.151 |
|
2010 |
Griffith TN, Varela-Nallar L, Dinamarca MC, Inestrosa NC. Neurobiological effects of Hyperforin and its potential in Alzheimer's disease therapy. Current Medicinal Chemistry. 17: 391-406. PMID 20015041 DOI: 10.2174/092986710790226156 |
0.15 |
|
2016 |
Tapia-Rojas C, Burgos PV, Inestrosa NC. Inhibition of Wnt signaling induces amyloidogenic processing of APP and the production and aggregation of Aβ42 peptides. Journal of Neurochemistry. PMID 27778356 DOI: 10.1111/jnc.13873 |
0.15 |
|
1984 |
Méndez B, Garrido J, Maldonado M, Jaksic FM, Inestrosa NC. The electric organ of Discopyge tschudii: its innervated face and the biology of acetylcholinesterase. Cellular and Molecular Neurobiology. 4: 125-42. PMID 6488242 DOI: 10.1007/Bf00711000 |
0.15 |
|
2012 |
Vergara J, Medina L, Maulén J, Inestrosa NC, Alvarez J. Nerve regeneration is improved by insulin-like growth factor I (IGF-I) and basic flbroblast growth factor (bFGF). Restorative Neurology and Neuroscience. 5: 181-9. PMID 21551900 DOI: 10.3233/RNN-1993-5302 |
0.15 |
|
2018 |
Tapia-Rojas C, Inestrosa NC. Loss of canonical Wnt signaling is involved in the pathogenesis of Alzheimer's disease. Neural Regeneration Research. 13: 1705-1710. PMID 30136680 DOI: 10.4103/1673-5374.238606 |
0.149 |
|
2021 |
Arredondo SB, Reyes DT, Herrera-Soto A, Mardones MD, Inestrosa NC, Varela-Nallar L. Andrographolide promotes hippocampal neurogenesis and spatial memory in the APPswe/PS1ΔE9 mouse model of Alzheimer's disease. Scientific Reports. 11: 22904. PMID 34824314 DOI: 10.1038/s41598-021-01977-x |
0.149 |
|
1996 |
Inestrosa NC, Alvarez A, Pérez CA, Moreno RD, Vicente M, Linker C, Casanueva OI, Soto C, Garrido J. Acetylcholinesterase accelerates assembly of amyloid-beta-peptides into Alzheimer's fibrils: possible role of the peripheral site of the enzyme. Neuron. 16: 881-91. PMID 8608006 DOI: 10.1016/S0896-6273(00)80108-7 |
0.148 |
|
2020 |
Viayna E, Coquelle N, Cieslikiewicz-Bouet M, Cisternas P, Oliva CA, Sánchez-López E, Ettcheto M, Bartolini M, De Simone A, Ricchini M, Rendina M, Pons M, Firuzi O, Pérez B, Saso L, ... ... Inestrosa NC, et al. Discovery of a Potent Dual Inhibitor of Acetylcholinesterase and Butyrylcholinesterase with Antioxidant Activity that Alleviates Alzheimer-like Pathology in Old APP/PS1 Mice. Journal of Medicinal Chemistry. PMID 33356266 DOI: 10.1021/acs.jmedchem.0c01775 |
0.148 |
|
1987 |
Inestrosa NC, Roberts WL, Marshall TL, Rosenberry TL. Acetylcholinesterase from bovine caudate nucleus is attached to membranes by a novel subunit distinct from those of acetylcholinesterases in other tissues. The Journal of Biological Chemistry. 262: 4441-4. PMID 3558347 |
0.148 |
|
2011 |
Rosas-Arellano A, Parodi J, Machuca-Parra AI, Sánchez-Gutiérrez A, Inestrosa NC, Miledi R, Martínez-Torres A. The GABA(A)ρ receptors in hippocampal spontaneous activity and their distribution in hippocampus, amygdala and visual cortex. Neuroscience Letters. 500: 20-5. PMID 21683123 DOI: 10.1016/J.Neulet.2011.05.235 |
0.148 |
|
1991 |
Cambiazo V, Inestrosa NC. Proteoglycan production in Drosophila egg development: effect of beta-D-xyloside on proteoglycan synthesis and larvae motility. Comparative Biochemistry and Physiology. B, Comparative Biochemistry. 97: 307-14. PMID 2123767 DOI: 10.1016/0305-0491(90)90286-3 |
0.148 |
|
2014 |
Zolezzi JM, Bastías-Candia S, Santos MJ, Inestrosa NC. Alzheimer's disease: relevant molecular and physiopathological events affecting amyloid-β brain balance and the putative role of PPARs. Frontiers in Aging Neuroscience. 6: 176. PMID 25120477 DOI: 10.3389/fnagi.2014.00176 |
0.147 |
|
2023 |
Oliva CA, Rivera DS, Torres AK, Lindsay CB, Tapia-Rojas C, Bozinovic F, Inestrosa NC. Age-Dependent Behavioral and Synaptic Dysfunction Impairment Are Improved with Long-Term Andrographolide Administration in Long-Lived Female Degus (). International Journal of Molecular Sciences. 24. PMID 36674622 DOI: 10.3390/ijms24021105 |
0.147 |
|
2012 |
Inestrosa NC, Fernández HL. Is there a correspondence between half-lives of motor endplate acetylcholinesterase and junctional acetylcholine receptors? Neuroscience Letters. 5: 91-3. PMID 19604976 DOI: 10.1016/0304-3940(77)90170-7 |
0.146 |
|
2014 |
Montecinos-Oliva C, Schuller A, Parodi J, Melo F, Inestrosa NC. Effects of tetrahydrohyperforin in mouse hippocampal slices: neuroprotection, long-term potentiation and TRPC channels. Current Medicinal Chemistry. 21: 3494-506. PMID 25039785 |
0.145 |
|
2014 |
Godoy JA, Zolezzi JM, Braidy N, Inestrosa NC. Role of Sirt1 during the ageing process: relevance to protection of synapses in the brain. Molecular Neurobiology. 50: 744-56. PMID 24496572 DOI: 10.1007/s12035-014-8645-5 |
0.145 |
|
1983 |
Inestrosa NC, Méndez B. The A12 acetylcholinesterase and polypeptide composition of electric organ basal lamina of Electrophorus and some Torpedinae fishes. Cell Biochemistry and Function. 1: 41-8. PMID 6678617 DOI: 10.1002/cbf.290010108 |
0.144 |
|
2002 |
Inestrosa N, De Ferrari GV, Garrido JL, Alvarez A, Olivares GH, BarrÃa MI, Bronfman M, Chacón MA. Wnt signaling involvement in beta-amyloid-dependent neurodegeneration. Neurochemistry International. 41: 341-4. PMID 12176076 DOI: 10.1016/S0197-0186(02)00056-6 |
0.143 |
|
1989 |
Prieto AL, Fuentes ME, Arqueros L, Inestrosa NC. Phosphatidylinositol-specific phospholipase C solubilized G2 acetylcholinesterase from plasma membranes of chromaffin cells. Journal of Neuroscience Research. 24: 169-73. PMID 2585545 DOI: 10.1002/jnr.490240207 |
0.143 |
|
2022 |
Oliva CA, Rivera DS, Mariqueo TA, Bozinovic F, Inestrosa NC. Differential Role of Sex and Age in the Synaptic Transmission of Degus (). Frontiers in Integrative Neuroscience. 16: 799147. PMID 35295186 DOI: 10.3389/fnint.2022.799147 |
0.143 |
|
2013 |
Zolezzi JM, Inestrosa NC. Peroxisome proliferator-activated receptors and Alzheimer's disease: hitting the blood-brain barrier. Molecular Neurobiology. 48: 438-51. PMID 23494748 DOI: 10.1007/s12035-013-8435-5 |
0.142 |
|
1977 |
Inestrosa NC, Ramírez BU, Fernández HL. Effects of denervation and of axoplasmic transport blockage on the in vitro release of muscle endplate acetylcholinesterase. Journal of Neurochemistry. 28: 941-5. PMID 68100 DOI: 10.1111/j.1471-4159.1977.tb10654.x |
0.141 |
|
2004 |
Reyes AE, Chacón MA, Dinamarca MC, Cerpa W, Morgan C, Inestrosa NC. Acetylcholinesterase-Abeta complexes are more toxic than Abeta fibrils in rat hippocampus: effect on rat beta-amyloid aggregation, laminin expression, reactive astrocytosis, and neuronal cell loss. The American Journal of Pathology. 164: 2163-74. PMID 15161650 DOI: 10.1016/S0002-9440(10)63774-1 |
0.14 |
|
2012 |
Inestrosa NC, Fernandez HL, Garrido J. Actin-like filaments in synaptosomes detected by heavy meromyosin binding. Neuroscience Letters. 2: 217-21. PMID 19604844 DOI: 10.1016/0304-3940(76)90018-5 |
0.14 |
|
1996 |
Moreno RD, Inestrosa NC, Culwell AR, Alvarez J. Sprouting and abnormal contacts of nonmedullated axons, and deposition of extracellular material induced by the amyloid precursor protein (APP) and other protease inhibitors. Brain Research. 718: 13-24. PMID 8773762 DOI: 10.1016/0006-8993(95)01555-8 |
0.14 |
|
1976 |
Ferdandez HL, Inestrosa NC. Role of axoplasmic transport in neurotrophic regulation of muscle end plate acetylcholinesterase. Nature. 262: 55-6. PMID 59316 DOI: 10.1038/262055a0 |
0.14 |
|
2015 |
Segovia-Miranda F, Serrano F, Dyrda A, Ampuero E, Retamal C, Bravo-Zehnder M, Parodi J, Zamorano P, Valenzuela D, Massardo L, van Zundert B, Inestrosa NC, González A. Pathogenicity of lupus anti-ribosomal p antibodies: role of cross-reacting neuronal surface p antigen in glutamatergic transmission and plasticity in a mouse model. Arthritis & Rheumatology (Hoboken, N.J.). 67: 1598-610. PMID 25709106 DOI: 10.1002/art.39081 |
0.139 |
|
2021 |
Inestrosa NC, Tapia-Rojas C, Cerpa W, Cisternas P, Zolezzi JM. WNT Signaling Is a Key Player in Alzheimer's Disease. Handbook of Experimental Pharmacology. PMID 34486097 DOI: 10.1007/164_2021_532 |
0.139 |
|
1983 |
Inestrosa NC, Fernandez HL. Turnover rates of cat skeletal muscle soluble enzymes. Cellular and Molecular Biology. 28: 541-5. PMID 6820640 |
0.139 |
|
1988 |
Ruiz G, Flores OG, González-Plaza R, Inestrosa NC. Effect of phenytoin on cytoskeletal protein phosphorylation and neuronal structure in the rat sensory cortex. Journal of Neuroscience Research. 18: 466-72. PMID 2449538 DOI: 10.1002/jnr.490180313 |
0.139 |
|
1998 |
Alvarez A, Alarcón R, Opazo C, Campos EO, Muñoz FJ, Calderón FH, Dajas F, Gentry MK, Doctor BP, De Mello FG, Inestrosa NC. Stable complexes involving acetylcholinesterase and amyloid-beta peptide change the biochemical properties of the enzyme and increase the neurotoxicity of Alzheimer's fibrils. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 3213-23. PMID 9547230 |
0.138 |
|
2000 |
Miranda S, Opazo C, Larrondo LF, Muñoz FJ, Ruiz F, Leighton F, Inestrosa NC. The role of oxidative stress in the toxicity induced by amyloid β-peptide in Alzheimer's disease Progress in Neurobiology. 62: 633-648. PMID 10880853 DOI: 10.1016/S0301-0082(00)00015-0 |
0.138 |
|
2016 |
Rivera DS, Lindsay C, Codocedo JF, Morel I, Pinto C, Cisternas P, Bozinovic F, Inestrosa NC. Andrographolide recovers cognitive impairment in a natural model of Alzheimer's disease (Octodon degus). Neurobiology of Aging. 46: 204-220. PMID 27505720 DOI: 10.1016/j.neurobiolaging.2016.06.021 |
0.138 |
|
2007 |
Fuentealba RA, Barría MI, Lee J, Cam J, Araya C, Escudero CA, Inestrosa NC, Bronfman FC, Bu G, Marzolo MP. ApoER2 expression increases Abeta production while decreasing Amyloid Precursor Protein (APP) endocytosis: Possible role in the partitioning of APP into lipid rafts and in the regulation of gamma-secretase activity. Molecular Neurodegeneration. 2: 14. PMID 17620134 DOI: 10.1186/1750-1326-2-14 |
0.138 |
|
2015 |
Bastías-Candia S, Nicolás Garrido A, Zolezzi JM, Inestrosa NC. Recent Advances in Neuroinflammation Therapeutics: PPARs/LXR as Neuroinflammatory Modulators. Current Pharmaceutical Design. PMID 26696410 |
0.137 |
|
2008 |
Cancino GI, Toledo EM, Leal NR, Hernandez DE, Yévenes LF, Inestrosa NC, Alvarez AR. STI571 prevents apoptosis, tau phosphorylation and behavioural impairments induced by Alzheimer's beta-amyloid deposits. Brain : a Journal of Neurology. 131: 2425-42. PMID 18559370 DOI: 10.1093/Brain/Awn125 |
0.136 |
|
2014 |
Quintanilla RA, von Bernhardi R, Godoy JA, Inestrosa NC, Johnson GV. Phosphorylated tau potentiates Aβ-induced mitochondrial damage in mature neurons. Neurobiology of Disease. 71: 260-9. PMID 25134729 DOI: 10.1016/j.nbd.2014.08.016 |
0.136 |
|
2011 |
Lorca RA, Varela-Nallar L, Inestrosa NC, Huidobro-Toro JP. The Cellular Prion Protein Prevents Copper-Induced Inhibition of P2X(4) Receptors. International Journal of Alzheimer's Disease. 2011: 706576. PMID 22114745 DOI: 10.4061/2011/706576 |
0.135 |
|
2004 |
Colombres M, Sagal JP, Inestrosa NC. An overview of the current and novel drugs for Alzheimer's disease with particular reference to anti-cholinesterase compounds Current Pharmaceutical Design. 10: 3121-3130. PMID 15544502 DOI: 10.2174/1381612043383359 |
0.135 |
|
2003 |
Lorca RA, Chacón M, BarrÃa MI, Inestrosa NC, Huidobro-Toro JP. The human prion octarepeat fragment prevents and reverses the inhibitory action of copper in the P2X4 receptor without modifying the zinc action. Journal of Neurochemistry. 85: 709-16. PMID 12694397 DOI: 10.1046/J.1471-4159.2003.01705.X |
0.134 |
|
2018 |
Cisternas P, Zolezzi JM, Martinez M, Torres VI, Wong GW, Inestrosa NC. Wnt-induced activation of glucose metabolism mediates the in vivo neuroprotective roles of Wnt signaling in Alzheimer disease. Journal of Neurochemistry. PMID 30300917 DOI: 10.1111/jnc.14608 |
0.134 |
|
2005 |
Quintanilla RA, Muñoz FJ, Metcalfe MJ, Hitschfeld M, Olivares G, Godoy JA, Inestrosa NC. Trolox and 17beta-estradiol protect against amyloid beta-peptide neurotoxicity by a mechanism that involves modulation of the Wnt signaling pathway. The Journal of Biological Chemistry. 280: 11615-25. PMID 15659394 DOI: 10.1074/jbc.M411936200 |
0.134 |
|
2002 |
Morgan C, Bugueño MP, Garrido J, Inestrosa NC. Laminin affects polymerization, depolymerization and neurotoxicity of Aβ peptide Peptides. 23: 1229-1240. PMID 12128080 DOI: 10.1016/S0196-9781(02)00058-X |
0.134 |
|
2003 |
Leisewitz AV, Jung JE, Perez-Alzola P, Fuenzalida KM, Roth A, Inestrosa NC, Bronfman M. Ethanol specifically decreases peroxisome proliferator activated receptor β in B12 oligodendrocyte-like cells Journal of Neurochemistry. 85: 135-141. PMID 12641735 DOI: 10.1046/J.1471-4159.2003.01641.X |
0.133 |
|
2006 |
Kemmerling U, Cabrera G, Campos EO, Inestrosa NC, Galanti N. Localization, specific activity, and molecular forms of acetylcholinesterase in developmental stages of the cestode Mesocestoides corti Journal of Cellular Physiology. 206: 503-509. PMID 16155922 DOI: 10.1002/jcp.20495 |
0.132 |
|
1987 |
Inestrosa NC, Sunkel C, Arriagada J. The sensory projections of Drosophila mutants which show abnormal wing formation or flying behavior Brain Research. 416: 248-256. PMID 3113669 DOI: 10.1016/0006-8993(87)90904-8 |
0.131 |
|
2015 |
Lambert C, Cisternas P, Inestrosa NC. Role of Wnt Signaling in Central Nervous System Injury. Molecular Neurobiology. PMID 25976365 DOI: 10.1007/s12035-015-9138-x |
0.13 |
|
1991 |
González R, Campos EO, Morán S, Inestrosa NC. Characterization of acetylcholinesterase from human heart auricles: evidence for the presence of a G-form sensitive to phosphatidylinositol-specific phospholipase c. General Pharmacology. 22: 107-10. PMID 1646743 DOI: 10.1016/0306-3623(91)90318-Z |
0.13 |
|
2018 |
Cisternas P, Martinez M, Ahima RS, William Wong G, Inestrosa NC. Modulation of Glucose Metabolism in Hippocampal Neurons by Adiponectin and Resistin. Molecular Neurobiology. PMID 30076527 DOI: 10.1007/s12035-018-1271-x |
0.13 |
|
1988 |
Fuentes ME, Rosenberry TL, Inestrosa NC. A 13 kDa fragment is responsible for the hydrophobic aggregation of brain G4 acetylcholinesterase. The Biochemical Journal. 256: 1047-50. PMID 3223943 DOI: 10.1042/bj2561047 |
0.13 |
|
2000 |
Deprez P, Inestrosa NC. Molecular modeling of the collagen-like tail of asymmetric acetylcholinesterase Protein Engineering. 13: 27-34. PMID 10679527 |
0.129 |
|
2013 |
Zolezzi JM, Silva-Alvarez C, Ordenes D, Godoy JA, Carvajal FJ, Santos MJ, Inestrosa NC. Peroxisome proliferator-activated receptor (PPAR) γ and PPARα agonists modulate mitochondrial fusion-fission dynamics: relevance to reactive oxygen species (ROS)-related neurodegenerative disorders? Plos One. 8: e64019. PMID 23675519 DOI: 10.1371/journal.pone.0064019 |
0.128 |
|
2012 |
Ardiles AO, Tapia-Rojas CC, Mandal M, Alexandre F, Kirkwood A, Inestrosa NC, Palacios AG. Postsynaptic dysfunction is associated with spatial and object recognition memory loss in a natural model of Alzheimer's disease. Proceedings of the National Academy of Sciences of the United States of America. 109: 13835-40. PMID 22869717 DOI: 10.1073/pnas.1201209109 |
0.128 |
|
2003 |
Chacón MA, BarrÃa MI, Lorca R, Huidobro-Toro JP, Inestrosa NC. A human prion protein peptide (PrP(59-91)) protects against copper neurotoxicity. Molecular Psychiatry. 8: 853-62, 835. PMID 14515136 DOI: 10.1038/sj.mp.4001400 |
0.127 |
|
2003 |
Roth AD, Leisewitz AV, Jung JE, Cassina P, Barbeito L, Inestrosa NC, Bronfman M. PPAR gamma activators induce growth arrest and process extension in B12 oligodendrocyte-like cells and terminal differentiation of cultured oligodendrocytes. Journal of Neuroscience Research. 72: 425-35. PMID 12704804 DOI: 10.1002/Jnr.10596 |
0.127 |
|
2001 |
Morgan C, Inestrosa NC. Interactions of laminin with the amyloid ß peptide. Implications for Alzheimer's disease Brazilian Journal of Medical and Biological Research. 34: 597-601. PMID 11323745 |
0.127 |
|
1988 |
Inestrosa NC, Alvarez J. Axons grow in the aging rat but fast transport and acetylcholinesterase content remain unchanged. Brain Research. 441: 331-8. PMID 2451983 DOI: 10.1016/0006-8993(88)91411-4 |
0.127 |
|
2019 |
Toledo C, Andrade DC, Díaz HS, Inestrosa NC, Del Rio R. Neurocognitive Disorders in Heart Failure: Novel Pathophysiological Mechanisms Underpinning Memory Loss and Learning Impairment. Molecular Neurobiology. PMID 31165973 DOI: 10.1007/s12035-019-01655-0 |
0.127 |
|
2015 |
Tapia-Rojas C, Aranguiz F, Varela-Nallar L, Inestrosa NC. Voluntary Running Attenuates Memory Loss, Decreases Neuropathological Changes and Induces Neurogenesis in a Mouse Model of Alzheimer's Disease. Brain Pathology (Zurich, Switzerland). PMID 25763997 DOI: 10.1111/bpa.12255 |
0.127 |
|
2008 |
Inestrosa NC, Dinamarca MC, Alvarez A. Amyloid-cholinesterase interactions: Implications for Alzheimer's disease Febs Journal. 275: 625-632. PMID 18205831 DOI: 10.1111/j.1742-4658.2007.06238.x |
0.127 |
|
2003 |
Opazo C, Inés Barría M, Ruiz FH, Inestrosa NC. Copper reduction by copper binding proteins and its relation to neurodegenerative diseases Biometals. 16: 91-98. PMID 12572668 DOI: 10.1023/A:1020795422185 |
0.126 |
|
1995 |
Tapia M, Inestrosa NC, Alvarez J. Early axonal regeneration: repression by Schwann cells and a protease? Experimental Neurology. 131: 124-32. PMID 7534718 DOI: 10.1016/0014-4886(95)90014-4 |
0.126 |
|
2010 |
Varela-Nallar L, Aranguiz FC, Abbott AC, Slater PG, Inestrosa NC. Adult hippocampal neurogenesis in aging and Alzheimer's disease. Birth Defects Research. Part C, Embryo Today : Reviews. 90: 284-96. PMID 21181889 DOI: 10.1002/bdrc.20193 |
0.126 |
|
2015 |
Cuevas CA, Tapia-Rojas C, Cespedes C, Inestrosa NC, Vio CP. β-Catenin-Dependent Signaling Pathway Contributes to Renal Fibrosis in Hypertensive Rats. Biomed Research International. 2015: 726012. PMID 25945342 DOI: 10.1155/2015/726012 |
0.125 |
|
1982 |
Inestrosa NC, Fernandez HL. Gangliosides and sialoglycoproteins in normal and denervated rat diaphragm muscle. Muscle & Nerve. 5: 33-8. PMID 7057803 DOI: 10.1002/mus.880050107 |
0.125 |
|
1999 |
Inestrosa NC, Alarcón R. Molecular interactions of acetylcholinesterase with senile plaques. Journal of Physiology, Paris. 92: 341-4. PMID 9789834 DOI: 10.1016/S0928-4257(99)80002-3 |
0.125 |
|
2005 |
Inestrosa NC, Reyes AE, Chacón MA, Cerpa W, Villalón A, Montiel J, Merabachvili G, Aldunate R, Bozinovic F, Aboitiz F. Human-like rodent amyloid-beta-peptide determines Alzheimer pathology in aged wild-type Octodon degu. Neurobiology of Aging. 26: 1023-8. PMID 15748782 DOI: 10.1016/J.Neurobiolaging.2004.09.016 |
0.124 |
|
2020 |
Rivera DS, Lindsay CB, Oliva CA, Codocedo JF, Bozinovic F, Inestrosa NC. Effects of long-lasting social isolation and re-socialization on cognitive performance and brain activity: a longitudinal study in Octodon degus. Scientific Reports. 10: 18315. PMID 33110163 DOI: 10.1038/s41598-020-75026-4 |
0.122 |
|
1999 |
Inestrosa NC, Marzolo MP, Bonnefont AB. Cellular and molecular basis of estrogen's neuroprotection. Potential relevance for Alzheimer's disease. Molecular Neurobiology. 17: 73-86. PMID 9887447 DOI: 10.1007/BF02802025 |
0.122 |
|
2009 |
Minniti AN, Cataldo R, Trigo C, Vasquez L, Mujica P, Leighton F, Inestrosa NC, Aldunate R. Methionine sulfoxide reductase A expression is regulated by the DAF-16/FOXO pathway in Caenorhabditis elegans. Aging Cell. 8: 690-705. PMID 19747232 DOI: 10.1111/j.1474-9726.2009.00521.x |
0.121 |
|
2014 |
Zolezzi JM, Inestrosa NC. Brain metabolite clearance: impact on Alzheimer's disease. Metabolic Brain Disease. 29: 553-61. PMID 24664180 DOI: 10.1007/s11011-014-9527-2 |
0.121 |
|
2010 |
Toledo EM, Inestrosa NC. Wnt signaling activation reduces neuropathological markers in a mouse model of Alzheimer's disease Molecular Psychiatry. 15: 228. DOI: 10.1038/Mp.2010.9 |
0.12 |
|
1994 |
Inestrosa NC, Alarcón R, Arriagada J, Donoso A, Alvarez J, Campos EO. Blood markers in Alzheimer disease: subnormal acetylcholinesterase and butyrylcholinesterase in lymphocytes and erythrocytes. Journal of the Neurological Sciences. 122: 1-5. PMID 8195795 DOI: 10.1016/0022-510X(94)90044-2 |
0.12 |
|
2005 |
Inestrosa NC, Cerpa W, Varela-Nallar L. Copper brain homeostasis: role of amyloid precursor protein and prion protein. Iubmb Life. 57: 645-50. PMID 16203684 DOI: 10.1080/15216540500264620 |
0.12 |
|
2017 |
Zolezzi JM, Inestrosa NC. Wnt/TLR Dialog in Neuroinflammation, Relevance in Alzheimer's Disease. Frontiers in Immunology. 8: 187. PMID 28286503 DOI: 10.3389/fimmu.2017.00187 |
0.119 |
|
2016 |
Martínez G, Vidal RL, Mardones P, Serrano FG, Ardiles AO, Wirth C, Valdés P, Thielen P, Schneider BL, Kerr B, Valdés JL, Palacios AG, Inestrosa NC, Glimcher LH, Hetz C. Regulation of Memory Formation by the Transcription Factor XBP1. Cell Reports. PMID 26854229 DOI: 10.1016/J.Celrep.2016.01.028 |
0.119 |
|
1999 |
Bonnefont AB, Muñoz FJ, Inestrosa NC. Estrogen protects neuronal cells from the cytotoxicity induced by acetylcholinesterase-amyloid complexes. Febs Letters. 441: 220-4. PMID 9883888 DOI: 10.1016/S0014-5793(98)01552-X |
0.118 |
|
2019 |
Toledo C, Lucero C, Andrade DC, Díaz HS, Schwarz KG, Pereyra KV, Arce-Álvarez A, López NA, Martinez M, Inestrosa NC, Del Rio R. Cognitive impairment in heart failure is associated with altered Wnt signaling in the hippocampus. Aging. PMID 31447429 DOI: 10.18632/aging.102150 |
0.118 |
|
2006 |
Varela-Nallar L, Toledo EM, Chacón MA, Inestrosa NC. The functional links between prion protein and copper. Biological Research. 39: 39-44. PMID 16629163 DOI: 10.4067/S0716-97602006000100005 |
0.118 |
|
2013 |
Zolezzi JM, Carvajal FJ, RÃos JA, Ordenes D, Silva-Alvarez C, Godoy JA, Inestrosa NC. Tetrahydrohyperforin induces mitochondrial dynamics and prevents mitochondrial Ca2+ overload after Aβ and Aβ-AChE complex challenge in rat hippocampal neurons. Journal of Alzheimer's Disease : Jad. 37: 735-46. PMID 23948911 DOI: 10.3233/JAD-130173 |
0.116 |
|
2010 |
Hödar C, Assar R, Colombres M, Aravena A, Pavez L, González M, MartÃnez S, Inestrosa NC, Maass A. Genome-wide identification of new Wnt/beta-catenin target genes in the human genome using CART method. Bmc Genomics. 11: 348. PMID 20515496 DOI: 10.1186/1471-2164-11-348 |
0.116 |
|
2022 |
Villaseca P, Cisternas P, Inestrosa NC. Menopause and development of Alzheimer's disease: Roles of neural glucose metabolism and Wnt signaling. Frontiers in Endocrinology. 13: 1021796. PMID 36339406 DOI: 10.3389/fendo.2022.1021796 |
0.116 |
|
2004 |
Morgan C, Colombres M, Nuñez MT, Inestrosa NC. Structure and function of amyloid in Alzheimer's disease Progress in Neurobiology. 74: 323-349. PMID 15649580 DOI: 10.1016/j.pneurobio.2004.10.004 |
0.115 |
|
1994 |
Inestrosa NC, Moreno RD, Fuentes ME. Monomeric amphiphilic forms of acetylcholinesterase appear early during brain development and may correspond to biosynthetic precursors of the amphiphilic G4 forms. Neuroscience Letters. 173: 155-8. PMID 7936404 DOI: 10.1016/0304-3940(94)90172-4 |
0.114 |
|
2017 |
Cisternas P, Inestrosa NC. Brain glucose metabolism: role of Wnt signaling in the metabolic impairment in Alzheimer's disease. Neuroscience and Biobehavioral Reviews. PMID 28624434 DOI: 10.1016/j.neubiorev.2017.06.004 |
0.114 |
|
1988 |
Fuentes ME, Inestrosa NC. Characterization of a tetrameric G4 form of acetylcholinesterase from bovine brain: a comparison with the dimeric G2 form of the electric organ. Molecular and Cellular Biochemistry. 81: 53-64. PMID 3173345 DOI: 10.1007/BF00225653 |
0.114 |
|
2010 |
Cerpa W, Hancke JL, Morazzoni P, Bombardelli E, Riva A, Marin PP, Inestrosa NC. The hyperforin derivative IDN5706 occludes spatial memory impairments and neuropathological changes in a double transgenic Alzheimer's mouse model. Current Alzheimer Research. 7: 126-33. PMID 19939230 DOI: 10.2174/156720510790691218 |
0.114 |
|
2015 |
Cuevas CA, Gonzalez AA, Inestrosa NC, Vio CP, Prieto MC. Angiotensin II increases fibronectin and collagen I through the β-catenin-dependent signaling in mouse collecting duct cells. American Journal of Physiology. Renal Physiology. 308: F358-65. PMID 25411386 DOI: 10.1152/Ajprenal.00429.2014 |
0.113 |
|
1998 |
Campos EO, Alvarez A, Inestrosa NC. Brain acetylcholinesterase promotes amyloid-beta-peptide aggregation but does not hydrolyze amyloid precursor protein peptides. Neurochemical Research. 23: 135-40. PMID 9475506 DOI: 10.1023/A:1022416505725 |
0.113 |
|
2015 |
Du LY, Chang LY, Ardiles AO, Tapia-Rojas C, Araya J, Inestrosa NC, Palacios AG, Acosta ML. Alzheimer's Disease-Related Protein Expression in the Retina of Octodon degus. Plos One. 10: e0135499. PMID 26267479 DOI: 10.1371/journal.pone.0135499 |
0.113 |
|
2008 |
Rebolledo DL, Minniti AN, Grez PM, Fadic R, Kohn R, Inestrosa NC. Inclusion body myositis: a view from the Caenorhabditis elegans muscle. Molecular Neurobiology. 38: 178-98. PMID 18773311 DOI: 10.1007/s12035-008-8041-0 |
0.113 |
|
2009 |
Inestrosa NC, Grabowski C, Arrázola M, Varela-Nallar L, Toledo EM. Role of Alzheimer's β-Amyloid on Wnt signaling Protein Misfolding Disorders: a Trip Into the Er. 103-113. DOI: 10.2174/978160805013010901010103 |
0.112 |
|
1994 |
Soto C, Brañes MC, Alvarez J, Inestrosa NC. Structural determinants of the Alzheimer's amyloid beta-peptide. Journal of Neurochemistry. 63: 1191-8. PMID 7931272 DOI: 10.1046/j.1471-4159.1994.63041191.x |
0.112 |
|
2001 |
De Ferrari GV, Canales MA, Shin I, Weiner LM, Silman I, Inestrosa NC. A structural motif of acetylcholinesterase that promotes amyloid beta-peptide fibril formation. Biochemistry. 40: 10447-57. PMID 11523986 DOI: 10.1021/Bi0101392 |
0.11 |
|
2000 |
Ruiz FH, Silva E, Inestrosa NC. The N-terminal tandem repeat region of human prion protein reduces copper: Role of tryptophan residues Biochemical and Biophysical Research Communications. 269: 491-495. PMID 10708581 DOI: 10.1006/bbrc.2000.2270 |
0.11 |
|
1996 |
Bronfman FC, Garrido J, Alvarez A, Morgan C, Inestrosa NC. Laminin inhibits amyloid-beta-peptide fibrillation. Neuroscience Letters. 218: 201-3. PMID 8945763 DOI: 10.1016/S0304-3940(96)13147-5 |
0.109 |
|
1997 |
Alvarez A, Opazo C, Alarcón R, Garrido J, Inestrosa NC. Acetylcholinesterase promotes the aggregation of amyloid-beta-peptide fragments by forming a complex with the growing fibrils. Journal of Molecular Biology. 272: 348-61. PMID 9325095 DOI: 10.1006/jmbi.1997.1245 |
0.109 |
|
2006 |
Dinamarca MC, Cerpa W, Garrido J, Hancke JL, Inestrosa NC. Hyperforin prevents beta-amyloid neurotoxicity and spatial memory impairments by disaggregation of Alzheimer's amyloid-beta-deposits. Molecular Psychiatry. 11: 1032-48. PMID 16880827 DOI: 10.1038/sj.mp.4001866 |
0.108 |
|
1989 |
Inestrosa NC, Cross D. Expression of size-selected messenger RNA encoding the brain and adrenal gland angiotensin-II receptor in Xenopus laevis oocytes. Archivos De Biologia Y Medicina Experimentales. 21: 423-8. PMID 3256274 |
0.108 |
|
2008 |
Dinamarca MC, Arrázola M, Toledo E, Cerpa WF, Hancke J, Inestrosa NC. Release of acetylcholinesterase (AChE) from beta-amyloid plaques assemblies improves the spatial memory impairments in APP-transgenic mice. Chemico-Biological Interactions. 175: 142-9. PMID 18599028 DOI: 10.1016/J.Cbi.2008.05.026 |
0.107 |
|
2018 |
Godoy JA, Valdivieso AG, Inestrosa NC. Nicotine Modulates Mitochondrial Dynamics in Hippocampal Neurons. Molecular Neurobiology. PMID 29619740 DOI: 10.1007/s12035-018-1034-8 |
0.107 |
|
1999 |
Muñoz FJ, Inestrosa NC. Neurotoxicity of acetylcholinesterase amyloid beta-peptide aggregates is dependent on the type of Abeta peptide and the AChE concentration present in the complexes. Febs Letters. 450: 205-9. PMID 10359075 DOI: 10.1016/S0014-5793(99)00468-8 |
0.106 |
|
2004 |
Doss-Pepe E, Deprez P, Silva T, Inestrosa NC, Kirkpatrick A, Ramshaw JAM, Brodsky B. Stepwise construction of triple-helical heparin binding sites using peptide models Biochimica Et Biophysica Acta - Proteins and Proteomics. 1698: 187-195. PMID 15134651 DOI: 10.1016/j.bbapap.2003.11.034 |
0.106 |
|
1986 |
Fiedler JL, Inestrosa NC, Bustos G. Putative glutamate receptors in membranes obtained from heads of Drosophila melanogaster. Journal of Neuroscience Research. 16: 505-15. PMID 2877097 DOI: 10.1002/jnr.490160306 |
0.106 |
|
1998 |
Bronfman FC, Alvarez A, Morgan C, Inestrosa NC. Laminin blocks the assembly of wild-type A beta and the Dutch variant peptide into Alzheimer's fibrils. Amyloid : the International Journal of Experimental and Clinical Investigation : the Official Journal of the International Society of Amyloidosis. 5: 16-23. PMID 9547001 DOI: 10.3109/13506129809007285 |
0.106 |
|
2002 |
Muñoz FJ, Opazo C, Gil-Gómez G, Tapia G, Fernández V, Valverde MA, Inestrosa NC. Vitamin E but not 17beta-estradiol protects against vascular toxicity induced by beta-amyloid wild type and the Dutch amyloid variant. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 3081-9. PMID 11943811 |
0.105 |
|
2009 |
Minniti AN, Rebolledo DL, Grez PM, Fadic R, Aldunate R, Volitakis I, Cherny RA, Opazo C, Masters C, Bush AI, Inestrosa NC. Intracellular amyloid formation in muscle cells of Abeta-transgenic Caenorhabditis elegans: determinants and physiological role in copper detoxification. Molecular Neurodegeneration. 4: 2. PMID 19126228 DOI: 10.1186/1750-1326-4-2 |
0.104 |
|
1995 |
Inestrosa NC, Soto C. Molecular biology of the amyloid of Alzheimer's disease. An overview. Biological Research. 25: 63-72. PMID 1365703 |
0.103 |
|
2022 |
Novoa C, Salazar P, Cisternas P, Gherardelli C, Vera-Salazar R, Zolezzi JM, Inestrosa NC. Inflammation context in Alzheimer's disease, a relationship intricate to define. Biological Research. 55: 39. PMID 36550479 DOI: 10.1186/s40659-022-00404-3 |
0.103 |
|
2000 |
Opazo C, Ruiz FH, Inestrosa NC. Amyloid-β-peptide reduces copper(II) to copper(I) independent of its aggregation state Biological Research. 33: 125-131. PMID 15693279 |
0.103 |
|
2016 |
Estrada LD, Chamorro D, Yañez MJ, Gonzalez M, Leal N, von Bernhardi R, Dulcey AE, Marugan J, Ferrer M, Soto C, Zanlungo S, Inestrosa NC, Alvarez AR. Reduction of Blood Amyloid-β Oligomers in Alzheimer's Disease Transgenic Mice by c-Abl Kinase Inhibition. Journal of Alzheimer's Disease : Jad. PMID 27567806 DOI: 10.3233/Jad-151087 |
0.103 |
|
2015 |
Cisternas P, Lindsay CB, Salazar P, Silva-Alvarez C, Retamales RM, Serrano FG, Vio CP, Inestrosa NC. The increased potassium intake improves cognitive performance and attenuates histopathological markers in a model of Alzheimer's disease. Biochimica Et Biophysica Acta. 1852: 2630-44. PMID 26391254 DOI: 10.1016/j.bbadis.2015.09.009 |
0.102 |
|
2000 |
Deprez P, Doss-Pepe E, Brodsky B, Inestrosa NC. Interaction of the collagen-like tail of asymmetric acetylcholinesterase with heparin depends on triple-helical conformation, sequence and stability Biochemical Journal. 350: 283-290. PMID 10926855 DOI: 10.1042/0264-6021:3500283 |
0.102 |
|
2014 |
Ríos JA, Cisternas P, Arrese M, Barja S, Inestrosa NC. Is Alzheimer's disease related to metabolic syndrome? A Wnt signaling conundrum. Progress in Neurobiology. 121: 125-46. PMID 25084549 DOI: 10.1016/j.pneurobio.2014.07.004 |
0.102 |
|
2021 |
Cisternas P, Gherardelli C, Salazar P, Inestrosa NC. Disruption of Glucose Metabolism in Aged : A Sporadic Model of Alzheimer's Disease. Frontiers in Integrative Neuroscience. 15: 733007. PMID 34707484 DOI: 10.3389/fnint.2021.733007 |
0.102 |
|
2015 |
Bravo-Zehnder M, Toledo EM, Segovia-Miranda F, Serrano FG, Benito MJ, Metz C, Retamal C, Ãlvarez A, Massardo L, Inestrosa NC, González A. Anti-ribosomal P protein autoantibodies from patients with neuropsychiatric lupus impair memory in mice. Arthritis & Rheumatology (Hoboken, N.J.). 67: 204-14. PMID 25302407 DOI: 10.1002/Art.38900 |
0.101 |
|
2004 |
Chacón MA, BarrÃa MI, Soto C, Inestrosa NC. Beta-sheet breaker peptide prevents Abeta-induced spatial memory impairments with partial reduction of amyloid deposits. Molecular Psychiatry. 9: 953-61. PMID 15098004 DOI: 10.1038/Sj.Mp.4001516 |
0.1 |
|
1980 |
Inestrosa NC, Bronfman M, Leighton F. Detection of peroxisomal fatty acyl-coenzyme A oxidase activity. The Biochemical Journal. 182: 779-88. PMID 518563 DOI: 10.1042/bj1820779 |
0.1 |
|
2019 |
Lindsay CB, Zolezzi JM, Rivera DS, Cisternas P, Bozinovic F, Inestrosa NC. Andrographolide Reduces Neuroinflammation and Oxidative Stress in Aged Octodon degus. Molecular Neurobiology. PMID 31701436 DOI: 10.1007/s12035-019-01784-6 |
0.099 |
|
2022 |
Gherardelli C, Cisternas P, Inestrosa NC. Lithium Enhances Hippocampal Glucose Metabolism in an In Vitro Mice Model of Alzheimer's Disease. International Journal of Molecular Sciences. 23. PMID 35955868 DOI: 10.3390/ijms23158733 |
0.099 |
|
2023 |
Braidy N, Brew BJ, Inestrosa NC, Chung R, Sachdev P, Guillemin GJ. Retraction Note to: Changes in Cathepsin D and Beclin-1 mRNA and protein expression by the excitotoxin quinolinic acid in human astrocytes and neurons. Metabolic Brain Disease. PMID 37273082 DOI: 10.1007/s11011-023-01241-3 |
0.098 |
|
2014 |
Inestrosa NC, Ríos JA, Cisternas P, Tapia-Rojas C, Rivera DS, Braidy N, Zolezzi JM, Godoy JA, Carvajal FJ, Ardiles AO, Bozinovic F, Palacios AG, Sachdev PS. Age Progression of Neuropathological Markers in the Brain of the Chilean Rodent Octodon degus, a Natural Model of Alzheimer's Disease. Brain Pathology (Zurich, Switzerland). PMID 25351914 DOI: 10.1111/Bpa.12226 |
0.098 |
|
2000 |
Doss-Pepe E, Deprez P, Inestrosa NC, Brodsky B. Interaction of collagen-like peptide models of asymmetric acetylcholinesterase with glycosaminoglycans: Spectroscopic studies of conformational changes and stability Biochemistry. 39: 14884-14892. PMID 11101304 DOI: 10.1021/bi001108u |
0.098 |
|
2023 |
Cisternas P, Gherardelli C, Gutierrez J, Salazar P, Mendez-Orellana C, Wong GW, Inestrosa NC. Adiponectin and resistin modulate the progression of Alzheimer´s disease in a metabolic syndrome model. Frontiers in Endocrinology. 14: 1237796. PMID 37732123 DOI: 10.3389/fendo.2023.1237796 |
0.098 |
|
2005 |
Cerpa W, Varela-Nallar L, Reyes AE, Minniti AN, Inestrosa NC. Is there a role for copper in neurodegenerative diseases? Molecular Aspects of Medicine. 26: 405-20. PMID 16112188 DOI: 10.1016/J.Mam.2005.07.011 |
0.097 |
|
2015 |
Retamales-Ortega R, Vio CP, Inestrosa NC. P2C-Type ATPases and Their Regulation. Molecular Neurobiology. PMID 25631710 DOI: 10.1007/s12035-014-9076-z |
0.097 |
|
2018 |
Cisternas P, Zolezzi JM, Lindsay C, Rivera DS, Martinez A, Bozinovic F, Inestrosa NC. New Insights into the Spontaneous Human Alzheimer's Disease-Like Model Octodon degus: Unraveling Amyloid-β Peptide Aggregation and Age-Related Amyloid Pathology. Journal of Alzheimer's Disease : Jad. PMID 30412496 DOI: 10.3233/JAD-180729 |
0.096 |
|
2015 |
Minniti AN, Arrazola MS, Bravo-Zehnder M, Ramos F, Inestrosa NC, Aldunate R. The protein oxidation repair enzyme methionine sulfoxide reductase a modulates Aβ aggregation and toxicity in vivo. Antioxidants & Redox Signaling. 22: 48-62. PMID 24988428 DOI: 10.1089/ars.2013.5803 |
0.096 |
|
2006 |
Varela-Nallar L, González A, Inestrosa NC. Role of copper in prion diseases: Deleterious or beneficial? Current Pharmaceutical Design. 12: 2587-2595. PMID 16842180 DOI: 10.2174/138161206777698873 |
0.096 |
|
2012 |
Braidy N, Muñoz P, Palacios AG, Castellano-Gonzalez G, Inestrosa NC, Chung RS, Sachdev P, Guillemin GJ. Recent rodent models for Alzheimer's disease: clinical implications and basic research. Journal of Neural Transmission (Vienna, Austria : 1996). 119: 173-95. PMID 22086139 DOI: 10.1007/S00702-011-0731-5 |
0.096 |
|
2016 |
Cuevas CA, Tapia-Rojas C, Cespedes C, Inestrosa NC, Vio CP. Corrigendum to "β-Catenin-Dependent Signaling Pathway Contributes to Renal Fibrosis in Hypertensive Rats". Biomed Research International. 2016: 9672429. PMID 27803932 DOI: 10.1155/2016/9672429 |
0.095 |
|
1988 |
Cross D, Cifuentes F, Huidobro-Toro JP, Vío CP, Inestrosa NC. Synthesis and expression of functional angiotensin II receptors in Xenopus oocytes injected with rat brain mRNA. Brain Research. 388: 268-70. PMID 3676711 DOI: 10.1016/0169-328X(87)90034-9 |
0.095 |
|
2015 |
Lambert C, Cisternas P, Inestrosa NC. Role of Wnt Signaling in Central Nervous System Injury Molecular Neurobiology. DOI: 10.1007/s12035-015-9138-x |
0.093 |
|
2017 |
Braidy N, Poljak A, Marjo C, Rutlidge H, Rich A, Jugder BE, Jayasena T, Inestrosa NC, Sachdev PS. Identification of Cerebral Metal Ion Imbalance in the Brain of Aging Octodon degus. Frontiers in Aging Neuroscience. 9: 66. PMID 28405187 DOI: 10.3389/Fnagi.2017.00066 |
0.093 |
|
2023 |
Martinez A, Lamaizon CM, Valls C, Llambi F, Leal N, Fitzgerald P, Guy C, Kamiński MM, Inestrosa NC, van Zundert B, Cancino GI, Dulcey AE, Zanlungo S, Marugan JJ, Hetz C, et al. c-Abl Phosphorylates MFN2 to Regulate Mitochondrial Morphology in Cells under Endoplasmic Reticulum and Oxidative Stress, Impacting Cell Survival and Neurodegeneration. Antioxidants (Basel, Switzerland). 12. PMID 38001860 DOI: 10.3390/antiox12112007 |
0.093 |
|
2020 |
Gherardelli C, Cisternas P, Gutiérrez J, Martinez M, Inestrosa NC. Andrographolide restores glucose uptake in rat hippocampal neurons. Journal of Neurochemistry. PMID 33124061 DOI: 10.1111/jnc.15229 |
0.092 |
|
2014 |
Braidy N, Poljak A, Marjo C, Rutlidge H, Rich A, Jayasena T, Inestrosa NC, Sachdev P. Metal and complementary molecular bioimaging in Alzheimer's disease. Frontiers in Aging Neuroscience. 6: 138. PMID 25076902 DOI: 10.3389/Fnagi.2014.00138 |
0.091 |
|
2009 |
Vázquez MC, Vargas LM, Inestrosa NC, Alvarez AR. c-Abl modulates AICD dependent cellular responses: transcriptional induction and apoptosis. Journal of Cellular Physiology. 220: 136-43. PMID 19306298 DOI: 10.1002/jcp.21743 |
0.09 |
|
1998 |
Deprez P, Krejci E, Massoulié J, Inestrosa N. 26 Dissection of the heparin-binding domains present in the collagenic tail of mammalian acetylcholinesterase Journal of Physiology-Paris. 92: 425-426. DOI: 10.1016/S0928-4257(99)80038-2 |
0.09 |
|
2002 |
Opazo C, Huang X, Cherny RA, Moir RD, Roher AE, White AR, Cappai R, Masters CL, Tanzi RE, Inestrosa NC, Bush AI. Metalloenzyme-like activity of Alzheimer's disease beta-amyloid. Cu-dependent catalytic conversion of dopamine, cholesterol, and biological reducing agents to neurotoxic H(2)O(2). The Journal of Biological Chemistry. 277: 40302-8. PMID 12192006 DOI: 10.1074/Jbc.M206428200 |
0.089 |
|
1995 |
Soto C, Castaño EM, Frangione B, Inestrosa NC. The alpha-helical to beta-strand transition in the amino-terminal fragment of the amyloid beta-peptide modulates amyloid formation. The Journal of Biological Chemistry. 270: 3063-7. PMID 7852387 DOI: 10.1074/jbc.270.7.3063 |
0.087 |
|
1998 |
Alvarez A, Alarcón R, Opazo C, Campos EO, Muñoz FJ, Calderón FH, Dajas F, Gentry MK, Doctor BP, De Mello FG, Inestrosa NC. Stable Complexes Involving Acetylcholinesterase and Amyloid-β Peptide Change the Biochemical Properties of the Enzyme and Increase the Neurotoxicity of Alzheimer’s Fibrils The Journal of Neuroscience. 18: 3213-3223. DOI: 10.1523/JNEUROSCI.18-09-03213.1998 |
0.086 |
|
1993 |
Gonzalez RA, Campos EO, Karmelic C, Moran S, Inestrosa NC. Acetylcholinesterase changes in hearts with sinus rhythm and atrial fibrillation. General Pharmacology. 24: 111-4. PMID 8482484 DOI: 10.1016/0306-3623(93)90019-T |
0.085 |
|
1985 |
Bronfman M, Inestrosa NC, Nervi FO, Leighton F. Acyl-CoA synthetase and the peroxisomal enzymes of beta-oxidation in human liver. Quantitative analysis of their subcellular localization. The Biochemical Journal. 224: 709-20. PMID 6240978 DOI: 10.1042/bj2240709 |
0.084 |
|
2015 |
Braidy N, Poljak A, Jayasena T, Mansour H, Inestrosa NC, Sachdev PS. Accelerating Alzheimer's research through 'natural' animal models. Current Opinion in Psychiatry. 28: 155-64. PMID 25602247 DOI: 10.1097/Yco.0000000000000137 |
0.083 |
|
2006 |
Inestrosa NC, Farías G, Colombres M. Glycogen Synthase Kinase 3β (GSK-3β) a Key Signaling Enzyme: A Developmental Neurobiological Perspective Glycogen Synthase Kinase 3 (Gsk-3) and Its Inhibitors: Drug Discovery and Development. 25-43. DOI: 10.1002/9780470052174.ch2 |
0.082 |
|
2023 |
Schwarz KG, Vicencio SC, Inestrosa NC, Villaseca P, Del Rio R. Autonomic nervous system dysfunction throughout menopausal transition: A potential mechanism underpinning cardiovascular and cognitive alterations during female ageing. The Journal of Physiology. 602: 263-280. PMID 38064358 DOI: 10.1113/JP285126 |
0.082 |
|
2021 |
Carreño DV, Corro NB, Cerda-Infante JF, Echeverría CE, Asencio-Barría CA, Torres-Estay VA, Mayorga-Weber GA, Rojas PA, Véliz LP, Cisternas PA, Montecinos VP, San Francisco IF, Varas-Godoy MA, Sotomayor PC, Castro MA, ... ... Inestrosa NC, et al. Dietary Fructose Promotes Prostate Cancer Growth. Cancer Research. PMID 33762358 DOI: 10.1158/0008-5472.CAN-19-0456 |
0.081 |
|
1998 |
Opazo C, Inestrosa NC. Crosslinking of amyloid-beta peptide to brain acetylcholinesterase. Molecular and Chemical Neuropathology. 33: 39-49. PMID 9493175 DOI: 10.1007/BF02815858 |
0.081 |
|
2023 |
Oliva CA, Lira M, Jara C, Catenaccio A, Mariqueo TA, Lindsay CB, Bozinovic F, Cavieres G, Inestrosa NC, Tapia-Rojas C, Rivera DS. Long-term social isolation stress exacerbates sex-specific neurodegeneration markers in a natural model of Alzheimer's disease. Frontiers in Aging Neuroscience. 15: 1250342. PMID 37810621 DOI: 10.3389/fnagi.2023.1250342 |
0.081 |
|
1999 |
Contreras CF, Canales MA, Alvarez A, De Ferrari GV, Inestrosa NC. Molecular modeling of the amyloid-β-peptide using the homology to a fragment of triosephosphate isomerase that forms amyloid in vitro Protein Engineering. 12: 959-966. PMID 10585501 |
0.081 |
|
2016 |
González A, Cavieres VA, Inestrosa NC, Burgos PV. Tetrahydrohyperforin (IDN5706) targets the endoplasmic reticulum for autophagy activation: potential mechanism for Alzheimer's disease therapy. Neural Regeneration Research. 11: 242-3. PMID 27073374 DOI: 10.4103/1673-5374.177728 |
0.081 |
|
2009 |
Suazo M, Hodar C, Morgan C, Cerpa W, Cambiazo V, Inestrosa NC, Gonzalez M. Overexpression of amyloid precursor protein increases copper content in HEK293 cells. Biochemical and Biophysical Research Communications. 382: 740-4. PMID 19318086 DOI: 10.1016/J.Bbrc.2009.03.096 |
0.079 |
|
2022 |
Mello-Carpes PB, Inestrosa NC, Paula-Lima AC. Editorial: Molecular mechanisms of Alzheimer's disease: From top to bottom. Frontiers in Aging. 3: 1026942. PMID 36187848 DOI: 10.3389/fragi.2022.1026942 |
0.076 |
|
2015 |
Du LY, Chang LYL, Ardiles A, Tapia-Rojas C, Araya J, Inestrosa NC, Palacios AG, Acosta ML. Alzheimer's disease-related protein expression in the retina of Octodon degus Plos One. 10. DOI: 10.1371/journal.pone.0135499 |
0.075 |
|
2022 |
Gherardelli C, Cisternas P, Vera-Salazar RF, Mendez-Orellana C, Inestrosa NC. Age- and Sex-Associated Glucose Metabolism Decline in a Mouse Model of Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 35404275 DOI: 10.3233/JAD-215273 |
0.075 |
|
2001 |
De Ferrari GV, Mallender WD, Inestrosa NC, Rosenberry TL. Thioflavin T Is a Fluorescent Probe of the Acetylcholinesterase Peripheral Site That Reveals Conformational Interactions between the Peripheral and Acylation Sites Journal of Biological Chemistry. 276: 23282-23287. PMID 11313335 DOI: 10.1074/jbc.M009596200 |
0.075 |
|
1996 |
Inestrosa NC, Sunkel CE, Arriagada J, Garrido J, Godoy-Herrera R. Abnormal development of the locomotor activity in yellow larvae of Drosophila: a cuticular defect? Genetica. 97: 205-10. PMID 8901139 DOI: 10.1007/Bf00054627 |
0.074 |
|
1997 |
Inestrosa NC, Alvarez A, Calderón F. Acetylcholinesterase is a senile plaque component that promotes assembly of amyloid beta-peptide into Alzheimer's filaments. Molecular Psychiatry. 1: 359-61. PMID 9154226 |
0.074 |
|
2015 |
Arrázola MS, Inestrosa NC. Monitoring mitochondrial membranes permeability in live neurons and mitochondrial swelling through electron microscopy analysis. Methods in Molecular Biology (Clifton, N.J.). 1254: 87-97. PMID 25431059 DOI: 10.1007/978-1-4939-2152-2_7 |
0.073 |
|
1995 |
Alvarez A, Bronfman F, Pérez CA, Vicente M, Garrido J, Inestrosa NC. Acetylcholinesterase, a senile plaque component, affects the fibrillogenesis of amyloid-β-peptides Neuroscience Letters. 201: 49-52. PMID 8830310 DOI: 10.1016/0304-3940(94)12127-C |
0.073 |
|
2005 |
Von Bernhardi R, Alarcón R, Mezzano D, Fuentes P, Inestrosa NC. Blood cells cholinesterase activity in early stage Alzheimer's disease and vascular dementia Dementia and Geriatric Cognitive Disorders. 19: 204-212. PMID 15677868 DOI: 10.1159/000083500 |
0.072 |
|
2012 |
Assar R, Leisewitz AV, Garcia A, Inestrosa NC, Montecino MA, Sherman DJ. Reusing and composing models of cell fate regulation of human bone precursor cells. Bio Systems. 108: 63-72. PMID 22309764 DOI: 10.1016/j.biosystems.2012.01.008 |
0.07 |
|
1995 |
Chen M, Inestrosa NC, Ross GS, Fernandez HL. Platelets are the primary source of amyloid beta-peptide in human blood. Biochemical and Biophysical Research Communications. 213: 96-103. PMID 7639768 DOI: 10.1006/bbrc.1995.2103 |
0.069 |
|
2015 |
Codocedo JF, Ríos JA, Godoy JA, Inestrosa NC. Are microRNAs the Molecular Link Between Metabolic Syndrome and Alzheimer's Disease? Molecular Neurobiology. PMID 25976367 DOI: 10.1007/s12035-015-9201-7 |
0.068 |
|
1990 |
Inestrosa NC, Perelman A. Association of acetylcholinesterase with the cell surface. The Journal of Membrane Biology. 118: 1-9. PMID 2283677 DOI: 10.1007/BF01872200 |
0.066 |
|
1999 |
Ruiz FH, González M, Bodini M, Opazo C, Inestrosa NC. Cysteine 144 is a key residue in the copper reduction by the beta-amyloid precursor protein. Journal of Neurochemistry. 73: 1288-92. PMID 10461923 DOI: 10.1046/j.1471-4159.1999.0731288.x |
0.066 |
|
2021 |
Schwarz KG, Pereyra KV, Toledo C, Andrade DC, Díaz HS, Díaz-Jara E, Ortolani D, Rios-Gallardo A, Arias P, Las Heras A, Vera I, Ortiz FC, Inestrosa NC, Vio CP, Del Rio R. Effects of enriched-potassium diet on cardiorespiratory outcomes in experimental non-ischemic chronic heart failure. Biological Research. 54: 43. PMID 34952651 DOI: 10.1186/s40659-021-00365-z |
0.066 |
|
2016 |
Rivera DS, Inestrosa NC, Bozinovic F. On cognitive ecology and the environmental factors that promote Alzheimer disease: lessons from Octodon degus (Rodentia: Octodontidae). Biological Research. 49: 10. PMID 26897365 DOI: 10.1186/s40659-016-0074-7 |
0.065 |
|
2018 |
Carreño D, Corro N, Torres-Estay V, Véliz LP, Jaimovich R, Cisternas P, San Francisco IF, Sotomayor PC, Tanasova M, Inestrosa NC, Godoy AS. Fructose and prostate cancer: toward an integrated view of cancer cell metabolism. Prostate Cancer and Prostatic Diseases. PMID 30104655 DOI: 10.1038/S41391-018-0072-7 |
0.064 |
|
2019 |
Zolezzi JM, Inestrosa NC. Diterpenes and the crosstalk with the arachidonic acid pathways, relevance in neurodegeneration. Neural Regeneration Research. 14: 1705-1706. PMID 31169181 DOI: 10.4103/1673-5374.257521 |
0.061 |
|
1980 |
Inestrosa NC, Bronfman M, Leighton F. Purification of the peroxisomal fatty acyl-CoA oxidase from rat liver. Biochemical and Biophysical Research Communications. 95: 7-12. PMID 7417271 DOI: 10.1016/0006-291X(80)90696-8 |
0.06 |
|
2015 |
Montecinos-Oliva C, Tapia-Rojas C, Burgos PV, Inestrosa NC. New discoveries on the hyperforin derivative, tetrahydrohyperforin: Closer to an Alzheimer'S disease treatment? Hypericum: Botanical Sources, Medical Properties and Health Effects. 119-137. |
0.059 |
|
2021 |
Rivera DS, Lindsay CB, Oliva CA, Bozinovic F, Inestrosa NC. A Multivariate Assessment of Age-Related Cognitive Impairment in . Frontiers in Integrative Neuroscience. 15: 719076. PMID 34526882 DOI: 10.3389/fnint.2021.719076 |
0.058 |
|
2004 |
Cerpa WF, BarrÃa MI, Chacón MA, Suazo M, González M, Opazo C, Bush AI, Inestrosa NC. The N-terminal copper-binding domain of the amyloid precursor protein protects against Cu2+ neurotoxicity in vivo. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 18: 1701-3. PMID 15345692 DOI: 10.1096/Fj.03-1349Fje |
0.057 |
|
1994 |
Inestrosa NC, Alarcón R, Arriagada J, Donoso A, Alvarez J. Platelet of Alzheimer patients: increased counts and subnormal uptake and accumulation of [14C]5-hydroxytryptamine. Neuroscience Letters. 163: 8-10. PMID 8295739 DOI: 10.1016/0304-3940(93)90216-8 |
0.057 |
|
1980 |
Inestrosa NC, Bronfman M, Leighton F. Properties of fatty acyl-CoA oxidase from rat liver, a peroxisomal flavoprotein. Life Sciences. 25: 1127-35. PMID 513950 DOI: 10.1016/0024-3205(79)90134-6 |
0.057 |
|
2021 |
Rivera DS, Lindsay CB, Oliva CA, Bozinovic F, Inestrosa NC. "Live together, die alone": The effect of re-socialization on behavioural performance and social-affective brain-related proteins after a long-term chronic social isolation stress. Neurobiology of Stress. 14: 100289. PMID 33426200 DOI: 10.1016/j.ynstr.2020.100289 |
0.055 |
|
2015 |
Montecinos-Oliva C, Schüller A, Inestrosa NC. Tetrahydrohyperforin: a neuroprotective modified natural compound against Alzheimer's disease. Neural Regeneration Research. 10: 552-4. PMID 26170810 DOI: 10.4103/1673-5374.155420 |
0.054 |
|
1998 |
Pérez D, Alarcón R, Inestrosa N. Kinetic and thermodynamic effects of acetylcholinesterase on the solubility of Aβ peptide Journal of Physiology-Paris. 92: 479. DOI: 10.1016/S0928-4257(99)80095-3 |
0.054 |
|
2023 |
Allendes FJ, Díaz HS, Ortiz FC, Marcus NJ, Quintanilla R, Inestrosa NC, Del Rio R. Cardiovascular and autonomic dysfunction in long-COVID syndrome and the potential role of non-invasive therapeutic strategies on cardiovascular outcomes. Frontiers in Medicine. 9: 1095249. PMID 36743679 DOI: 10.3389/fmed.2022.1095249 |
0.051 |
|
2008 |
Simonetta SH, Romanowski A, Minniti AN, Inestrosa NC, Golombek DA. Circadian stress tolerance in adult Caenorhabditis elegans. Journal of Comparative Physiology. a, Neuroethology, Sensory, Neural, and Behavioral Physiology. 194: 821-8. PMID 18648821 DOI: 10.1007/S00359-008-0353-Z |
0.05 |
|
2021 |
Salazar P, Villaseca P, Cisternas P, Inestrosa NC. Neurodevelopmental impact of the offspring by thyroid hormone system-disrupting environmental chemicals during pregnancy. Environmental Research. 200: 111345. PMID 34087190 DOI: 10.1016/j.envres.2021.111345 |
0.049 |
|
2018 |
Bastías-Candia S, Zolezzi JM, Inestrosa NC. Revisiting the Paraquat-Induced Sporadic Parkinson's Disease-Like Model. Molecular Neurobiology. PMID 29862459 DOI: 10.1007/s12035-018-1148-z |
0.048 |
|
2003 |
Chacón MA, Barría MI, Lorca R, Huidobro-Toro JP, Inestrosa NC. A human prion protein peptide (PrP59-91) protects against copper neurotoxicity Molecular Psychiatry. 8: 835+833. |
0.045 |
|
2020 |
Del Rio R, Marcus NJ, Inestrosa NC. Potential Role of Autonomic Dysfunction in Covid-19 Morbidity and Mortality. Frontiers in Physiology. 11: 561749. PMID 33178034 DOI: 10.3389/fphys.2020.561749 |
0.04 |
|
2015 |
Codocedo JF, Inestrosa NC. Environmental control of microRNAs in the nervous system: Implications in plasticity and behavior. Neuroscience and Biobehavioral Reviews. PMID 26593111 DOI: 10.1016/j.neubiorev.2015.10.010 |
0.039 |
|
1979 |
Bronfman M, Inestrosa NC, Leighton F. Fatty acid oxidation by human liver peroxisomes. Biochemical and Biophysical Research Communications. 88: 1030-6. PMID 465070 DOI: 10.1016/0006-291X(79)91512-2 |
0.026 |
|
1997 |
Martínez G, Muñoz GA, Campos EO, Inestrosa NC. Cyclic AMP and the reproductive process of the scallopArgopecten purpuratus The Journal of Experimental Zoology. 278: 243-249. DOI: 10.1002/(SICI)1097-010X(19970701)278:4<243::AID-JEZ5>3.0.CO;2-P |
0.024 |
|
2017 |
Braidy N, Poljak A, Marjo C, Rutlidge H, Rich A, Jugder BE, Jayasena T, Inestrosa NC, Sachdev PS. Corrigendum: Identification of Cerebral Metal Ion Imbalance in the Brain of Ageing Octodon degus. Frontiers in Aging Neuroscience. 9: 134. PMID 28515691 DOI: 10.3389/Fnagi.2017.00134 |
0.022 |
|
2022 |
Schwarz KG, Pereyra KV, Toledo C, Andrade DC, Díaz HS, Díaz-Jara E, Ortolani D, Rios-Gallardo A, Arias P, Heras AL, Vera I, Ortiz FC, Inestrosa NC, Vio CP, Del Rio R. Correction to: Effects of enriched-potassium diet on cardiorespiratory outcomes in experimental non-ischemic chronic heart failure. Biological Research. 55: 3. PMID 35063041 DOI: 10.1186/s40659-022-00370-w |
0.022 |
|
2016 |
Inestrosa NC, Santos MJ. Special series on trending themes in Neurobiology in Biological Research. Biological Research. 49: 19. PMID 26988549 DOI: 10.1186/s40659-016-0077-4 |
0.01 |
|
2011 |
Gonzalez-Billaul C, Inestrosa NC, Santos MJ. Contributions by researchers of "Ciencia de Frontera" of the Chilean Academy of Sciences. Biological Research. 44: 5. PMID 21720675 |
0.01 |
|
2006 |
Inestrosa N. Demencias: ¿qué hay de nuevo? avances en la neurobiología de la enfermedad de Alzheimer Medwave. 6. DOI: 10.5867/medwave.2006.02.1142 |
0.01 |
|
2004 |
Inestrosa NC. [Dr. Joaquín Luco Valenzuela. 1913-2002]. Biological Research. 36: 143-6. PMID 14513709 |
0.01 |
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