Suzanne J. Baker, Ph.D. - Publications

Affiliations: 
Developmental Neurobiology St. Jude Children's Research Hospital, San Francisco, CA, United States 
 University of Tennessee Health Science Center, Memphis, TN, United States 
Area:
PI3K-PTEN pathway, Pediatrics, Gliomas,
Website:
http://www.stjude.org/stjude/v/index.jsp?vgnextoid=a51c6f9523e70110VgnVCM1000001e0215acRCRD&cpsextcurrchannel=1

62 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Jin H, Kasper LH, Larson JD, Wu G, Baker SJ, Zhang J, Fan Y. ChIPseqSpikeInFree: A ChIP-seq normalization approach to reveal global changes in histone modifications without spike-in. Bioinformatics (Oxford, England). PMID 31566663 DOI: 10.1093/bioinformatics/btz720  0.36
2019 Silveira AB, Kasper LH, Fan Y, Jin H, Wu G, Shaw TI, Zhu X, Larson JD, Easton J, Shao Y, Yergeau DA, Rosencrance C, Boggs K, Rusch MC, Ding L, ... ... Baker SJ, et al. Correction to: H3.3 K27M depletion increases differentiation and extends latency of diffuse intrinsic pontine glioma growth in vivo. Acta Neuropathologica. PMID 30976974 DOI: 10.1007/s00401-019-02006-y  0.4
2019 Silveira AB, Kasper LH, Fan Y, Jin H, Wu G, Shaw TI, Zhu X, Larson JD, Easton J, Shao Y, Yergeau DA, Rosencrance C, Boggs K, Rusch MC, Ding L, ... ... Baker SJ, et al. H3.3 K27M depletion increases differentiation and extends latency of diffuse intrinsic pontine glioma growth in vivo. Acta Neuropathologica. PMID 30770999 DOI: 10.1007/s00401-019-01975-4  0.4
2018 Larson JD, Kasper LH, Paugh BS, Jin H, Wu G, Kwon CH, Fan Y, Shaw TI, Silveira AB, Qu C, Xu R, Zhu X, Zhang J, Russell HR, Peters JL, ... ... Baker SJ, et al. Histone H3.3 K27M Accelerates Spontaneous Brainstem Glioma and Drives Restricted Changes in Bivalent Gene Expression. Cancer Cell. PMID 30595505 DOI: 10.1016/j.ccell.2018.11.015  0.4
2018 Xu K, Ding L, Chang TC, Shao Y, Chiang J, Mulder H, Wang S, Shaw TI, Wen J, Hover L, McLeod C, Wang YD, Easton J, Rusch M, Dalton J, ... ... Baker SJ, et al. Structure and evolution of double minutes in diagnosis and relapse brain tumors. Acta Neuropathologica. PMID 30267146 DOI: 10.1007/s00401-018-1912-1  0.36
2017 Tinkle CL, Orr BA, Lucas JT, Klimo P, Patay Z, Baker SJ, Broniscer A, Qaddoumi I. Rapid and fulminant leptomeningeal spread following radiotherapy in diffuse intrinsic pontine glioma. Pediatric Blood & Cancer. PMID 28084680 DOI: 10.1002/pbc.26416  0.32
2016 Zhu G, Rankin SL, Larson JD, Zhu X, Chow LM, Qu C, Zhang J, Ellison DW, Baker SJ. PTEN signaling in the postnatal perivascular progenitor niche drives medulloblastoma formation. Cancer Research. PMID 27815386 DOI: 10.1158/0008-5472.CAN-16-1991  1
2016 Zhu G, Baker SJ. Detecting PTEN and PI3K Signaling in Brain. Methods in Molecular Biology (Clifton, N.J.). 1388: 53-62. PMID 27033070 DOI: 10.1007/978-1-4939-3299-3_5  1
2016 Qaddoumi I, Orisme W, Wen J, Santiago T, Gupta K, Dalton JD, Tang B, Haupfear K, Punchihewa C, Easton J, Mulder H, Boggs K, Shao Y, Rusch M, Becksfort J, ... ... Baker SJ, et al. Genetic alterations in uncommon low-grade neuroepithelial tumors: BRAF, FGFR1, and MYB mutations occur at high frequency and align with morphology. Acta Neuropathologica. PMID 26810070 DOI: 10.1007/s00401-016-1539-z  0.36
2015 Baker SJ, Ellison DW, Gutmann DH. Pediatric gliomas as neurodevelopmental disorders. Glia. PMID 26638183 DOI: 10.1002/glia.22945  1
2015 Chen X, Gupta P, Wang J, Nakitandwe J, Roberts K, Dalton JD, Parker M, Patel S, Holmfeldt L, Payne D, Easton J, Ma J, Rusch M, Wu G, Patel A, ... Baker SJ, et al. CONSERTING: integrating copy-number analysis with structural-variation detection. Nature Methods. 12: 527-30. PMID 25938371 DOI: 10.1038/nmeth.3394  1
2015 Zong H, Parada LF, Baker SJ. Cell of origin for malignant gliomas and its implication in therapeutic development. Cold Spring Harbor Perspectives in Biology. 7. PMID 25635044 DOI: 10.1101/cshperspect.a020610  1
2014 Misuraca KL, Barton KL, Chung A, Diaz AK, Conway SJ, Corcoran DL, Baker SJ, Becher OJ. Pax3 expression enhances PDGF-B-induced brainstem gliomagenesis and characterizes a subset of brainstem glioma. Acta Neuropathologica Communications. 2: 134. PMID 25330836 DOI: 10.1186/s40478-014-0134-6  1
2014 Jones C, Baker SJ. Unique genetic and epigenetic mechanisms driving paediatric diffuse high-grade glioma. Nature Reviews. Cancer. 14. PMID 25230881 DOI: 10.1038/nrc3811  1
2014 Diaz AK, Baker SJ. The genetic signatures of pediatric high-grade glioma: no longer a one-act play. Seminars in Radiation Oncology. 24: 240-7. PMID 25219808 DOI: 10.1016/j.semradonc.2014.06.003  1
2014 Huether R, Dong L, Chen X, Wu G, Parker M, Wei L, Ma J, Edmonson MN, Hedlund EK, Rusch MC, Shurtleff SA, Mulder HL, Boggs K, Vadordaria B, Cheng J, ... ... Baker SJ, et al. The landscape of somatic mutations in epigenetic regulators across 1,000 paediatric cancer genomes. Nature Communications. 5: 3630. PMID 24710217 DOI: 10.1038/ncomms4630  1
2014 Wu G, Diaz AK, Paugh BS, Rankin SL, Ju B, Li Y, Zhu X, Qu C, Chen X, Zhang J, Easton J, Edmonson M, Ma X, Lu C, Nagahawatte P, ... ... Baker SJ, et al. The genomic landscape of diffuse intrinsic pontine glioma and pediatric non-brainstem high-grade glioma. Nature Genetics. 46: 444-50. PMID 24705251 DOI: 10.1038/ng.2938  1
2013 Paugh BS, Zhu X, Qu C, Endersby R, Diaz AK, Zhang J, Bax DA, Carvalho D, Reis RM, Onar-Thomas A, Broniscer A, Wetmore C, Zhang J, Jones C, Ellison DW, ... Baker SJ, et al. Novel oncogenic PDGFRA mutations in pediatric high-grade gliomas. Cancer Research. 73: 6219-29. PMID 23970477 DOI: 10.1158/0008-5472.CAN-13-1491  1
2013 Rafalski VA, Ho PP, Brett JO, Ucar D, Dugas JC, Pollina EA, Chow LM, Ibrahim A, Baker SJ, Barres BA, Steinman L, Brunet A. Expansion of oligodendrocyte progenitor cells following SIRT1 inactivation in the adult brain. Nature Cell Biology. 15: 614-24. PMID 23644469 DOI: 10.1038/ncb2735  1
2013 Zhang J, Wu G, Miller CP, Tatevossian RG, Dalton JD, Tang B, Orisme W, Punchihewa C, Parker M, Qaddoumi I, Boop FA, Lu C, Kandoth C, Ding L, Lee R, ... ... Baker SJ, et al. Whole-genome sequencing identifies genetic alterations in pediatric low-grade gliomas. Nature Genetics. 45: 602-12. PMID 23583981 DOI: 10.1038/ng.2611  1
2013 Wu R, Baker SJ, Hu TC, Norman KM, Fearon ER, Cho KR. Type I to type II ovarian carcinoma progression: mutant Trp53 or Pik3ca confers a more aggressive tumor phenotype in a mouse model of ovarian cancer. The American Journal of Pathology. 182: 1391-9. PMID 23499052 DOI: 10.1016/j.ajpath.2012.12.031  1
2012 Parker M, Chen X, Bahrami A, Dalton J, Rusch M, Wu G, Easton J, Cheung NK, Dyer M, Mardis ER, Wilson RK, Mullighan C, Gilbertson R, Baker SJ, Zambetti G, et al. Assessing telomeric DNA content in pediatric cancers using whole-genome sequencing data. Genome Biology. 13: R113. PMID 23232254 DOI: 10.1186/gb-2012-13-12-r113  1
2012 Zhu G, Chow LM, Bayazitov IT, Tong Y, Gilbertson RJ, Zakharenko SS, Solecki DJ, Baker SJ. Pten deletion causes mTorc1-dependent ectopic neuroblast differentiation without causing uniform migration defects. Development (Cambridge, England). 139: 3422-31. PMID 22874917 DOI: 10.1242/dev.083154  1
2012 Robinson G, Parker M, Kranenburg TA, Lu C, Chen X, Ding L, Phoenix TN, Hedlund E, Wei L, Zhu X, Chalhoub N, Baker SJ, Huether R, Kriwacki R, Curley N, et al. Novel mutations target distinct subgroups of medulloblastoma. Nature. 488: 43-8. PMID 22722829 DOI: 10.1038/nature11213  1
2012 Chow LM, Baker SJ. Capturing the molecular and biological diversity of high-grade astrocytoma in genetically engineered mouse models. Oncotarget. 3: 67-77. PMID 22287481 DOI: 10.18632/oncotarget.425  1
2012 Wu G, Broniscer A, McEachron TA, Lu C, Paugh BS, Becksfort J, Qu C, Ding L, Huether R, Parker M, Zhang J, Gajjar A, Dyer MA, Mullighan CG, Gilbertson RJ, ... ... Baker SJ, et al. Somatic histone H3 alterations in pediatric diffuse intrinsic pontine gliomas and non-brainstem glioblastomas. Nature Genetics. 44: 251-3. PMID 22286216 DOI: 10.1038/ng.1102  1
2012 Sperow M, Berry RB, Bayazitov IT, Zhu G, Baker SJ, Zakharenko SS. Phosphatase and tensin homologue (PTEN) regulates synaptic plasticity independently of its effect on neuronal morphology and migration. The Journal of Physiology. 590: 777-92. PMID 22147265 DOI: 10.1113/jphysiol.2011.220236  1
2012 Rankin SL, Zhu G, Baker SJ. Review: insights gained from modelling high-grade glioma in the mouse. Neuropathology and Applied Neurobiology. 38: 254-70. PMID 22035336 DOI: 10.1111/j.1365-2990.2011.01231.x  1
2011 Nicolaides TP, Li H, Solomon DA, Hariono S, Hashizume R, Barkovich K, Baker SJ, Paugh BS, Jones C, Forshew T, Hindley GF, Hodgson JG, Kim JS, Rowitch DH, Weiss WA, et al. Targeted therapy for BRAFV600E malignant astrocytoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 17: 7595-604. PMID 22038996 DOI: 10.1158/1078-0432.CCR-11-1456  1
2011 Paugh BS, Broniscer A, Qu C, Miller CP, Zhang J, Tatevossian RG, Olson JM, Geyer JR, Chi SN, da Silva NS, Onar-Thomas A, Baker JN, Gajjar A, Ellison DW, Baker SJ. Genome-wide analyses identify recurrent amplifications of receptor tyrosine kinases and cell-cycle regulatory genes in diffuse intrinsic pontine glioma. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 29: 3999-4006. PMID 21931021 DOI: 10.1200/JCO.2011.35.5677  1
2011 Elmeliegy MA, Carcaboso AM, L Chow LM, Zhang ZM, Calabrese C, Throm SL, Wang F, Baker SJ, Stewart CF. Magnetic resonance imaging-guided microdialysis cannula implantation in a spontaneous high-grade glioma murine model. Journal of Pharmaceutical Sciences. 100: 4210-4. PMID 21837651 DOI: 10.1002/jps.22723  1
2011 Endersby R, Zhu X, Hay N, Ellison DW, Baker SJ. Nonredundant functions for Akt isoforms in astrocyte growth and gliomagenesis in an orthotopic transplantation model. Cancer Research. 71: 4106-16. PMID 21507933 DOI: 10.1158/0008-5472.CAN-10-3597  1
2011 Chow LM, Endersby R, Zhu X, Rankin S, Qu C, Zhang J, Broniscer A, Ellison DW, Baker SJ. Cooperativity within and among Pten, p53, and Rb pathways induces high-grade astrocytoma in adult brain. Cancer Cell. 19: 305-16. PMID 21397855 DOI: 10.1016/j.ccr.2011.01.039  0.4
2010 Tatevossian RG, Tang B, Dalton J, Forshew T, Lawson AR, Ma J, Neale G, Shurtleff SA, Bailey S, Gajjar A, Baker SJ, Sheer D, Ellison DW. MYB upregulation and genetic aberrations in a subset of pediatric low-grade gliomas. Acta Neuropathologica. 120: 731-43. PMID 21046410 DOI: 10.1007/s00401-010-0763-1  1
2010 Broniscer A, Baker JN, Baker SJ, Chi SN, Geyer JR, Morris EB, Gajjar A. Prospective collection of tissue samples at autopsy in children with diffuse intrinsic pontine glioma. Cancer. 116: 4632-7. PMID 20589749 DOI: 10.1002/cncr.25405  1
2010 Paugh BS, Qu C, Jones C, Liu Z, Adamowicz-Brice M, Zhang J, Bax DA, Coyle B, Barrow J, Hargrave D, Lowe J, Gajjar A, Zhao W, Broniscer A, Ellison DW, ... ... Baker SJ, et al. Integrated molecular genetic profiling of pediatric high-grade gliomas reveals key differences with the adult disease. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 28: 3061-8. PMID 20479398 DOI: 10.1200/JCO.2009.26.7252  1
2009 Chalhoub N, Zhu G, Zhu X, Baker SJ. Cell type specificity of PI3K signaling in Pdk1- and Pten-deficient brains. Genes & Development. 23: 1619-24. PMID 19605683 DOI: 10.1101/gad.1799609  1
2009 Cicero SA, Johnson D, Reyntjens S, Frase S, Connell S, Chow LM, Baker SJ, Sorrentino BP, Dyer MA. Cells previously identified as retinal stem cells are pigmented ciliary epithelial cells. Proceedings of the National Academy of Sciences of the United States of America. 106: 6685-90. PMID 19346468 DOI: 10.1073/pnas.0901596106  1
2009 Frappart PO, Lee Y, Russell HR, Chalhoub N, Wang YD, Orii KE, Zhao J, Kondo N, Baker SJ, McKinnon PJ. Recurrent genomic alterations characterize medulloblastoma arising from DNA double-strand break repair deficiency. Proceedings of the National Academy of Sciences of the United States of America. 106: 1880-5. PMID 19164512 DOI: 10.1073/pnas.0806882106  0.4
2009 Broniscer A, Baker SJ, Stewart CF, Merchant TE, Laningham FH, Schaiquevich P, Kocak M, Morris EB, Endersby R, Ellison DW, Gajjar A. Phase I and pharmacokinetic studies of erlotinib administered concurrently with radiotherapy for children, adolescents, and young adults with high-grade glioma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 15: 701-7. PMID 19147777 DOI: 10.1158/1078-0432.CCR-08-1923  1
2009 Chalhoub N, Baker SJ. PTEN and the PI3-kinase pathway in cancer. Annual Review of Pathology. 4: 127-50. PMID 18767981 DOI: 10.1146/annurev.pathol.4.110807.092311  1
2008 Chow LM, Zhang J, Baker SJ. Inducible Cre recombinase activity in mouse mature astrocytes and adult neural precursor cells. Transgenic Research. 17: 919-28. PMID 18483774 DOI: 10.1007/s11248-008-9185-4  0.36
2008 Weber T, Corbett MK, Chow LM, Valentine MB, Baker SJ, Zuo J. Rapid cell-cycle reentry and cell death after acute inactivation of the retinoblastoma gene product in postnatal cochlear hair cells. Proceedings of the National Academy of Sciences of the United States of America. 105: 781-5. PMID 18178626 DOI: 10.1073/pnas.0708061105  1
2007 Broniscer A, Baker SJ, West AN, Fraser MM, Proko E, Kocak M, Dalton J, Zambetti GP, Ellison DW, Kun LE, Gajjar A, Gilbertson RJ, Fuller CE. Clinical and molecular characteristics of malignant transformation of low-grade glioma in children. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 25: 682-9. PMID 17308273 DOI: 10.1200/JCO.2006.06.8213  1
2007 Baker SJ. PTEN enters the nuclear age. Cell. 128: 25-8. PMID 17218252 DOI: 10.1016/j.cell.2006.12.023  1
2006 Chow LM, Tian Y, Weber T, Corbett M, Zuo J, Baker SJ. Inducible Cre recombinase activity in mouse cerebellar granule cell precursors and inner ear hair cells. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 235: 2991-8. PMID 16958097 DOI: 10.1002/dvdy.20948  1
2006 Chalhoub N, Kozma SC, Baker SJ. S6k1 is not required for Pten-deficient neuronal hypertrophy. Brain Research. 1100: 32-41. PMID 16777079 DOI: 10.1016/j.brainres.2006.05.013  1
2006 Kwon CH, Luikart BW, Powell CM, Zhou J, Matheny SA, Zhang W, Li Y, Baker SJ, Parada LF. Pten regulates neuronal arborization and social interaction in mice. Neuron. 50: 377-88. PMID 16675393 DOI: 10.1016/j.neuron.2006.03.023  1
2006 Kwon CH, Zhou J, Li Y, Kim KW, Hensley LL, Baker SJ, Parada LF. Neuron-specific enolase-cre mouse line with cre activity in specific neuronal populations. Genesis (New York, N.Y. : 2000). 44: 130-5. PMID 16496331 DOI: 10.1002/gene.20197  1
2006 Chow LM, Baker SJ. PTEN function in normal and neoplastic growth. Cancer Letters. 241: 184-96. PMID 16412571 DOI: 10.1016/j.canlet.2005.11.042  1
2005 Abel TW, Baker SJ, Fraser MM, Tihan T, Nelson JS, Yachnis AT, Bouffard JP, Mena H, Burger PC, Eberhart CG. Lhermitte-Duclos disease: a report of 31 cases with immunohistochemical analysis of the PTEN/AKT/mTOR pathway. Journal of Neuropathology and Experimental Neurology. 64: 341-9. PMID 15835270  1
2004 Fraser MM, Zhu X, Kwon CH, Uhlmann EJ, Gutmann DH, Baker SJ. Pten loss causes hypertrophy and increased proliferation of astrocytes in vivo. Cancer Research. 64: 7773-9. PMID 15520182 DOI: 10.1158/0008-5472.CAN-04-2487  0.4
2004 Baker SJ, McKinnon PJ. Tumour-suppressor function in the nervous system. Nature Reviews. Cancer. 4: 184-96. PMID 14993900 DOI: 10.1038/nrc1297  1
2003 Baker SJ, Kinzler KW, Vogelstein B. Knudson's hypothesis and the TP53 revolution. Genes, Chromosomes & Cancer. 38: 329. PMID 14566852 DOI: 10.1002/gcc.10249  1
2003 Kwon CH, Zhu X, Zhang J, Baker SJ. mTor is required for hypertrophy of Pten-deficient neuronal soma in vivo. Proceedings of the National Academy of Sciences of the United States of America. 100: 12923-8. PMID 14534328 DOI: 10.1073/pnas.2132711100  0.4
2003 Torchia EC, Jaishankar S, Baker SJ. Ewing tumor fusion proteins block the differentiation of pluripotent marrow stromal cells. Cancer Research. 63: 3464-8. PMID 12839926  1
2003 Gutmann DH, Baker SJ, Giovannini M, Garbow J, Weiss W. Mouse models of human cancer consortium symposium on nervous system tumors. Cancer Research. 63: 3001-4. PMID 12782610  1
2003 Baker SJ. Redefining p53--entering the tumor suppressor era. Cell Cycle (Georgetown, Tex.). 2: 7-8. PMID 12695673  1
2001 Kwon CH, Zhu X, Zhang J, Knoop LL, Tharp R, Smeyne RJ, Eberhart CG, Burger PC, Baker SJ. Pten regulates neuronal soma size: a mouse model of Lhermitte-Duclos disease. Nature Genetics. 29: 404-11. PMID 11726927 DOI: 10.1038/ng781  1
2001 Zhu X, Kwon CH, Schlosshauer PW, Ellenson LH, Baker SJ. PTEN induces G(1) cell cycle arrest and decreases cyclin D3 levels in endometrial carcinoma cells. Cancer Research. 61: 4569-75. PMID 11389092  0.4
2001 Knoop LL, Baker SJ. EWS/FLI Alters 5′-Splice Site Selection Journal of Biological Chemistry. 276: 22317-22322. PMID 11301318 DOI: 10.1074/jbc.M008950200  1
2000 Knoop LL, Baker SJ. The splicing factor U1C represses EWS/FLI-mediated transactivation Journal of Biological Chemistry. 275: 24865-24871. PMID 10827180 DOI: 10.1074/jbc.M001661200  1
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