| Year |
Citation |
Score |
| 2024 |
Uehara K, Lee WD, Stefkovich M, Biswas D, Santoleri D, Garcia Whitlock AE, Quinn Iii WJ, Coopersmith TN, Creasy KT, Rader DJ, Sakamoto K, Rabinowitz JD, Titchenell PM. mTORC1 controls murine postprandial hepatic glycogen synthesis via Ppp1r3b. The Journal of Clinical Investigation. PMID 38290087 DOI: 10.1172/JCI173782 |
0.423 |
|
| 2023 |
Uehara K, Santoleri D, Whitlock AEG, Titchenell PM. Insulin Regulation of Hepatic Lipid Homeostasis. Comprehensive Physiology. 13: 4785-4809. PMID 37358513 DOI: 10.1002/cphy.c220015 |
0.408 |
|
| 2022 |
Santoleri D, Lim HW, Emmett MJ, Stoute J, Gavin MJ, Sostre-Colón J, Uehara K, Welles JE, Liu KF, Lazar MA, Titchenell PM. Global-run on sequencing identifies as an Akt-dependent long noncoding RNA involved in insulin sensitivity. Iscience. 25: 104410. PMID 35663017 DOI: 10.1016/j.isci.2022.104410 |
0.56 |
|
| 2022 |
Gosis BS, Wada S, Thorsheim C, Li K, Jung S, Rhoades JH, Yang Y, Brandimarto J, Li L, Uehara K, Jang C, Lanza M, Sanford NB, Bornstein MR, Jeong S, ... Titchenell PM, et al. Inhibition of nonalcoholic fatty liver disease in mice by selective inhibition of mTORC1. Science (New York, N.Y.). 376: eabf8271. PMID 35420934 DOI: 10.1126/science.abf8271 |
0.304 |
|
| 2022 |
Sostre-Colón J, Gavin MJ, Santoleri D, Titchenell PM. Acute Deletion of the FOXO1-dependent Hepatokine FGF21 Does not Alter Basal Glucose Homeostasis or Lipolysis in Mice. Endocrinology. 163. PMID 35303074 DOI: 10.1210/endocr/bqac035 |
0.413 |
|
| 2022 |
Uehara K, Sostre-Colón J, Gavin M, Santoleri D, Leonard KA, Jacobs RL, Titchenell PM. Activation of Liver mTORC1 Protects Against NASH via Dual Regulation of VLDL-TAG Secretion and De Novo Lipogenesis. Cellular and Molecular Gastroenterology and Hepatology. PMID 35240344 DOI: 10.1016/j.jcmgh.2022.02.015 |
0.348 |
|
| 2021 |
Sostre-Colón J, Uehara K, Garcia Whitlock AE, Gavin MJ, Ishibashi J, Potthoff MJ, Seale P, Titchenell PM. Hepatic AKT orchestrates adipose tissue thermogenesis via FGF21-dependent and -independent mechanisms. Cell Reports. 35: 109128. PMID 34010646 DOI: 10.1016/j.celrep.2021.109128 |
0.33 |
|
| 2021 |
Garcia Whitlock AE, Sostre-Colón J, Gavin M, Martin ND, Baur JA, Sims CA, Titchenell PM. Loss of FOXO transcription factors in the liver mitigates stress-induced hyperglycemia. Molecular Metabolism. 51: 101246. PMID 33964506 DOI: 10.1016/j.molmet.2021.101246 |
0.364 |
|
| 2020 |
Zhao S, Jang C, Liu J, Uehara K, Gilbert M, Izzo L, Zeng X, Trefely S, Fernandez S, Carrer A, Miller KD, Schug ZT, Snyder NW, Gade TP, Titchenell PM, et al. Dietary fructose feeds hepatic lipogenesis via microbiota-derived acetate. Nature. 579: 586-591. PMID 32214246 DOI: 10.1038/S41586-020-2101-7 |
0.399 |
|
| 2020 |
Shen Y, Su Y, Silva FJ, Weller AH, Sostre-Colón J, Titchenell PM, Steger DJ, Seale P, Soccio RE. Shared PPARα/γ Target Genes Regulate Brown Adipocyte Thermogenic Function. Cell Reports. 30: 3079-3091.e5. PMID 32130908 DOI: 10.1016/J.Celrep.2020.02.032 |
0.301 |
|
| 2020 |
Angueira AR, Shapira SN, Ishibashi J, Sampat S, Sostre-Colón J, Emmett MJ, Titchenell PM, Lazar MA, Lim HW, Seale P. Early B Cell Factor Activity Controls Developmental and Adaptive Thermogenic Gene Programming in Adipocytes. Cell Reports. 30: 2869-2878.e4. PMID 32130892 DOI: 10.1016/J.Celrep.2020.02.023 |
0.517 |
|
| 2019 |
Jaiswal N, Gavin MG, Quinn WJ, Luongo TS, Gelfer RG, Baur JA, Titchenell PM. The role of skeletal muscle Akt in the regulation of muscle mass and glucose homeostasis. Molecular Metabolism. PMID 31444134 DOI: 10.1016/J.Molmet.2019.08.001 |
0.405 |
|
| 2019 |
Ahn B, Wan S, Jaiswal N, Vega RB, Ayer DE, Titchenell PM, Han X, Won KJ, Kelly DP. MondoA drives muscle lipid accumulation and insulin resistance. Jci Insight. 5. PMID 31287806 DOI: 10.1172/Jci.Insight.129119 |
0.432 |
|
| 2019 |
Garcia Whitlock AE, Gavin M, Sims CA, Titchenell PM. Inhibition of the Liver Insulin Responsive Transcription Factor Forkhead Box Protein O1 Fails to Rescue Stress Hyperglycemia in Trauma and Hemorrhage Journal of the American College of Surgeons. 229: S299-S300. DOI: 10.1016/J.Jamcollsurg.2019.08.656 |
0.402 |
|
| 2018 |
Santoleri D, Titchenell PM. Resolving the Paradox of Hepatic Insulin Resistance. Cellular and Molecular Gastroenterology and Hepatology. 7: 447-456. PMID 30739869 DOI: 10.1016/J.Jcmgh.2018.10.016 |
0.496 |
|
| 2018 |
Lin CM, Titchenell PM, Keil JM, Garcia-Ocaña A, Bolinger MT, Abcouwer SF, Antonetti DA. Inhibition of Atypical Protein Kinase C Reduces Inflammation-Induced Retinal Vascular Permeability. The American Journal of Pathology. PMID 30220554 DOI: 10.1016/J.Ajpath.2018.06.020 |
0.606 |
|
| 2017 |
Quinn WJ, Wan M, Shewale SV, Gelfer R, Rader DJ, Birnbaum MJ, Titchenell PM. mTORC1 stimulates phosphatidylcholine synthesis to promote triglyceride secretion. The Journal of Clinical Investigation. PMID 29035283 DOI: 10.1172/Jci96036 |
0.572 |
|
| 2017 |
Titchenell PM, Lazar MA, Birnbaum MJ. Unraveling the Regulation of Hepatic Metabolism by Insulin. Trends in Endocrinology and Metabolism: Tem. PMID 28416361 DOI: 10.1016/J.Tem.2017.03.003 |
0.672 |
|
| 2016 |
Papazyan R, Sun Z, Kim YH, Titchenell PM, Hill DA, Lu W, Damle M, Wan M, Zhang Y, Briggs ER, Rabinowitz JD, Lazar MA. Physiological Suppression of Lipotoxic Liver Damage by Complementary Actions of HDAC3 and SCAP/SREBP. Cell Metabolism. PMID 27866836 DOI: 10.1016/J.Cmet.2016.10.012 |
0.554 |
|
| 2016 |
Jang H, Lee GY, Selby CP, Lee G, Jeon YG, Lee JH, Cheng KK, Titchenell P, Birnbaum MJ, Xu A, Sancar A, Kim JB. SREBP1c-CRY1 signalling represses hepatic glucose production by promoting FOXO1 degradation during refeeding. Nature Communications. 7: 12180. PMID 27412556 DOI: 10.1038/Ncomms12180 |
0.632 |
|
| 2016 |
Titchenell PM, Quinn WJ, Lu M, Chu Q, Lu W, Li C, Chen H, Monks BR, Chen J, Rabinowitz JD, Birnbaum MJ. Direct Hepatocyte Insulin Signaling Is Required for Lipogenesis but Is Dispensable for the Suppression of Glucose Production. Cell Metabolism. PMID 27238637 DOI: 10.1016/J.Cmet.2016.04.022 |
0.619 |
|
| 2015 |
Titchenell PM, Chu Q, Monks BR, Birnbaum MJ. Hepatic insulin signalling is dispensable for suppression of glucose output by insulin in vivo. Nature Communications. 6: 7078. PMID 25963408 DOI: 10.1038/Ncomms8078 |
0.63 |
|
| 2015 |
Perry RJ, Camporez JP, Kursawe R, Titchenell PM, Zhang D, Perry CJ, Jurczak MJ, Abudukadier A, Han MS, Zhang XM, Ruan HB, Yang X, Caprio S, Kaech SM, Sul HS, et al. Hepatic acetyl CoA links adipose tissue inflammation to hepatic insulin resistance and type 2 diabetes. Cell. 160: 745-58. PMID 25662011 DOI: 10.1016/J.Cell.2015.01.012 |
0.63 |
|
| 2014 |
Cannon CE, Titchenell PM, Groff DN, El Ouaamari A, Kulkarni RN, Birnbaum MJ, Stoffers DA. The Polycomb protein, Bmi1, regulates insulin sensitivity. Molecular Metabolism. 3: 794-802. PMID 25379404 DOI: 10.1016/J.Molmet.2014.08.002 |
0.554 |
|
| 2014 |
Patel K, Foretz M, Marion A, Campbell DG, Gourlay R, Boudaba N, Tournier E, Titchenell P, Peggie M, Deak M, Wan M, Kaestner KH, Göransson O, Viollet B, Gray NS, et al. The LKB1-salt-inducible kinase pathway functions as a key gluconeogenic suppressor in the liver. Nature Communications. 5: 4535. PMID 25088745 DOI: 10.1038/Ncomms5535 |
0.622 |
|
| 2013 |
Titchenell PM, Antonetti DA. Using the past to inform the future: anti-VEGF therapy as a road map to develop novel therapies for diabetic retinopathy. Diabetes. 62: 1808-15. PMID 23704522 DOI: 10.2337/Db12-1744 |
0.568 |
|
| 2013 |
Titchenell PM, Showalter HD, Pons JF, Barber AJ, Jin Y, Antonetti DA. Synthesis and structure-activity relationships of 2-amino-3-carboxy-4-phenylthiophenes as novel atypical protein kinase C inhibitors. Bioorganic & Medicinal Chemistry Letters. 23: 3034-8. PMID 23566515 DOI: 10.1016/J.Bmcl.2013.03.019 |
0.611 |
|
| 2012 |
Titchenell PM, Lin CM, Keil JM, Sundstrom JM, Smith CD, Antonetti DA. Novel atypical PKC inhibitors prevent vascular endothelial growth factor-induced blood-retinal barrier dysfunction. The Biochemical Journal. 446: 455-67. PMID 22721706 DOI: 10.1042/Bj20111961 |
0.664 |
|
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