Sergi Garcia-Manyes - Publications

Affiliations: 
2005-2011 Department of Biological Sc Columbia University, New York, NY 

62 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Andreu I, Granero-Moya I, Garcia-Manyes S, Roca-Cusachs P. Understanding the role of mechanics in nucleocytoplasmic transport. Apl Bioengineering. 6: 020901. PMID 35783457 DOI: 10.1063/5.0076034  0.303
2022 Mora M, Board S, Languin-Cattoën O, Masino L, Stirnemann G, Garcia-Manyes S. A Single-Molecule Strategy to Capture Non-native Intramolecular and Intermolecular Protein Disulfide Bridges. Nano Letters. 22: 3922-3930. PMID 35549281 DOI: 10.1021/acs.nanolett.2c00043  0.442
2021 Wallis SS, Ventimiglia LN, Otigbah E, Infante E, Cuesta-Geijo MA, Kidiyoor GR, Carbajal MA, Fleck RA, Foiani M, Garcia-Manyes S, Martin-Serrano J, Agromayor M. The ESCRT machinery counteracts Nesprin-2G-mediated mechanical forces during nuclear envelope repair. Developmental Cell. 56: 3192-3202.e8. PMID 34818527 DOI: 10.1016/j.devcel.2021.10.022  0.306
2021 Stannard A, Mora M, Beedle AEM, Castro-López M, Board S, Garcia-Manyes S. Molecular Fluctuations as a Ruler of Force-Induced Protein Conformations. Nano Letters. 21: 2953-2961. PMID 33765390 DOI: 10.1021/acs.nanolett.1c00051  0.57
2020 Mora M, Stannard A, Garcia-Manyes S. The nanomechanics of individual proteins. Chemical Society Reviews. PMID 32929436 DOI: 10.1039/D0Cs00426J  0.611
2019 Infante E, Stannard A, Board SJ, Rico-Lastres P, Rostkova E, Beedle AEM, Lezamiz A, Wang YJ, Gulaidi Breen S, Panagaki F, Sundar Rajan V, Shanahan C, Roca-Cusachs P, Garcia-Manyes S. The mechanical stability of proteins regulates their translocation rate into the cell nucleus Nature Physics. 15: 973-981. DOI: 10.1038/S41567-019-0551-3  0.432
2018 Beedle AEM, Mora M, Davis CT, Snijders AP, Stirnemann G, Garcia-Manyes S. Forcing the reversibility of a mechanochemical reaction. Nature Communications. 9: 3155. PMID 30089863 DOI: 10.1038/S41467-018-05115-6  0.534
2018 Wang Y, Rico-Lastres P, Lezamiz A, Mora M, Solsona C, Stirnemann G, Garcia-Manyes S. DNA Binding Induces a Nanomechanical Switch in the RRM1 Domain of TDP-43. The Journal of Physical Chemistry Letters. PMID 29924934 DOI: 10.1021/Acs.Jpclett.8B01494  0.492
2018 Perales-Calvo J, Giganti D, Stirnemann G, Garcia-Manyes S. The force-dependent mechanism of DnaK-mediated mechanical folding. Science Advances. 4: eaaq0243. PMID 29487911 DOI: 10.1126/Sciadv.Aaq0243  0.598
2017 Elosegui-Artola A, Andreu I, Beedle AEM, Lezamiz A, Uroz M, Kosmalska AJ, Oria R, Kechagia JZ, Rico-Lastres P, Le Roux AL, Shanahan CM, Trepat X, Navajas D, Garcia-Manyes S, Roca-Cusachs P. Force Triggers YAP Nuclear Entry by Regulating Transport across Nuclear Pores. Cell. PMID 29107331 DOI: 10.1016/J.Cell.2017.10.008  0.391
2017 Beedle AEM, Mora M, Lynham S, Stirnemann G, Garcia-Manyes S. Tailoring protein nanomechanics with chemical reactivity. Nature Communications. 8: 15658. PMID 28585528 DOI: 10.1038/Ncomms15658  0.539
2017 Relat-Goberna J, Beedle AEM, Garcia-Manyes S. The Nanomechanics of Lipid Multibilayer Stacks Exhibits Complex Dynamics. Small (Weinheim An Der Bergstrasse, Germany). 13. PMID 28503797 DOI: 10.1002/Smll.201700147  0.455
2017 Garcia-Manyes S, Beedle AEM. Steering chemical reactions with force Nature Reviews Chemistry. 1. DOI: 10.1038/S41570-017-0083  0.354
2016 Pernigo S, Fukuzawa A, Beedle AE, Holt M, Round A, Pandini A, Garcia-Manyes S, Gautel M, Steiner RA. Binding of Myomesin to Obscurin-Like-1 at the Muscle M-Band Provides a Strategy for Isoform-Specific Mechanical Protection. Structure (London, England : 1993). PMID 27989621 DOI: 10.1016/J.Str.2016.11.015  0.401
2016 Beedle AE, Lynham S, Garcia-Manyes S. Protein S-sulfenylation is a fleeting molecular switch that regulates non-enzymatic oxidative folding. Nature Communications. 7: 12490. PMID 27546612 DOI: 10.1038/Ncomms12490  0.523
2016 Perales-Calvo J, Giganti D, Garcia-Manyes S. Chaperone-Mediated Mechanical Protein Folding at the Single Molecule Level Biophysical Journal. 110: 392a. DOI: 10.1016/J.Bpj.2015.11.2120  0.503
2016 Beedle AE, Garcia-Manyes S. Linking Mechanochemistry to Protein Folding at the Single Bond Level Biophysical Journal. 110: 181a. DOI: 10.1016/J.Bpj.2015.11.1009  0.486
2015 Garcia-Manyes S, Giganti D, Badilla CL, Lezamiz A, Perales-Calvo J, Beedle AE, Fernández JM. Single molecule force spectroscopy predicts a misfolded, domain-swapped conformation in human γD-crystallin. The Journal of Biological Chemistry. PMID 26703476 DOI: 10.1074/Jbc.M115.673871  0.711
2015 Beedle AE, Williams A, Relat-Goberna J, Garcia-Manyes S. Mechanobiology-chemical origin of membrane mechanical resistance and force-dependent signaling. Current Opinion in Chemical Biology. 29: 87-93. PMID 26517566 DOI: 10.1016/J.Cbpa.2015.09.019  0.478
2015 Perales-Calvo J, Lezamiz A, Garcia-Manyes S. The Mechanochemistry of a Structural Zinc Finger. The Journal of Physical Chemistry Letters. 6: 3335-40. PMID 26296179 DOI: 10.1021/Acs.Jpclett.5B01371  0.51
2015 Beedle AE, Lezamiz A, Stirnemann G, Garcia-Manyes S. The mechanochemistry of copper reports on the directionality of unfolding in model cupredoxin proteins. Nature Communications. 6: 7894. PMID 26235284 DOI: 10.1038/Ncomms8894  0.546
2015 Relat-Goberna J, Garcia-Manyes S. Direct Observation of the Dynamics of Self-Assembly of Individual Solvation Layers in Molecularly Confined Liquids. Physical Review Letters. 114: 258303. PMID 26197150 DOI: 10.1103/Physrevlett.114.258303  0.32
2013 Popa I, Kosuri P, Alegre-Cebollada J, Garcia-Manyes S, Fernandez JM. Force dependency of biochemical reactions measured by single-molecule force-clamp spectroscopy. Nature Protocols. 8: 1261-76. PMID 23744288 DOI: 10.1038/Nprot.2013.056  0.794
2012 Berkovich R, Hermans RI, Popa I, Stirnemann G, Garcia-Manyes S, Berne BJ, Fernandez JM. Rate limit of protein elastic response is tether dependent. Proceedings of the National Academy of Sciences of the United States of America. 109: 14416-21. PMID 22895787 DOI: 10.1073/Pnas.1212167109  0.787
2012 Garcia-Manyes S, Badilla CL, Alegre-Cebollada J, Javadi Y, Fernández JM. Spontaneous dimerization of titin protein Z1Z2 domains induces strong nanomechanical anchoring. The Journal of Biological Chemistry. 287: 20240-7. PMID 22523089 DOI: 10.1074/Jbc.M112.355883  0.807
2012 Berkovich R, Hermans RI, Garcia-Manyes S, Fernandez JM. Direct Measurement of the Diffusion Dynamics of an Extended Poly-Ubiquitin Under Constant Force Biophysical Journal. 102: 12a. DOI: 10.1016/J.Bpj.2011.11.090  0.815
2011 Popa I, Fernández JM, Garcia-Manyes S. Direct quantification of the attempt frequency determining the mechanical unfolding of ubiquitin protein. The Journal of Biological Chemistry. 286: 31072-9. PMID 21768096 DOI: 10.1074/Jbc.M111.264093  0.802
2011 Perez-Jimenez R, Inglés-Prieto A, Zhao ZM, Sanchez-Romero I, Alegre-Cebollada J, Kosuri P, Garcia-Manyes S, Kappock TJ, Tanokura M, Holmgren A, Sanchez-Ruiz JM, Gaucher EA, Fernandez JM. Single-molecule paleoenzymology probes the chemistry of resurrected enzymes. Nature Structural & Molecular Biology. 18: 592-6. PMID 21460845 DOI: 10.1038/Nsmb.2020  0.747
2011 Garcia-Manyes S, Kuo TL, Fernández JM. Contrasting the individual reactive pathways in protein unfolding and disulfide bond reduction observed within a single protein. Journal of the American Chemical Society. 133: 3104-13. PMID 21309561 DOI: 10.1021/Ja109865Z  0.706
2011 Berkovich R, Garcia-Manyes S, Klafter J, Urbakh M, Fernandez JM. An Intrusive Entropic Barrier Induced by Force Biophysical Journal. 100. DOI: 10.1016/J.Bpj.2010.12.3066  0.634
2011 Garcia-Manyes S, Kuo T, Fernández JM. Protein Unfolding and Chemical Reactions Under Force: Complexity Versus Simplicity Biophysical Journal. 100. DOI: 10.1016/J.Bpj.2010.12.2815  0.541
2011 Popa I, Garcia-Manyes S, Fernandez JM. Temperature Dependence of the Mechanical Unfolding of Single Ubiquitin Proteins Biophysical Journal. 100: 398a. DOI: 10.1016/J.Bpj.2010.12.2362  0.807
2010 Berkovich R, Garcia-Manyes S, Klafter J, Urbakh M, Fernández JM. Hopping around an entropic barrier created by force. Biochemical and Biophysical Research Communications. 403: 133-7. PMID 21050839 DOI: 10.1016/J.Bbrc.2010.10.133  0.739
2010 Garcia-Manyes S. Single-molecule kinetics: Caught in the act. Nature Chemistry. 2: 905-6. PMID 20966939 DOI: 10.1038/Nchem.882  0.368
2010 Garcia-Manyes S, Redondo-Morata L, Oncins G, Sanz F. Nanomechanics of lipid bilayers: heads or tails? Journal of the American Chemical Society. 132: 12874-86. PMID 20799688 DOI: 10.1021/Ja1002185  0.424
2010 Kuo TL, Garcia-Manyes S, Li J, Barel I, Lu H, Berne BJ, Urbakh M, Klafter J, Fernández JM. Probing static disorder in Arrhenius kinetics by single-molecule force spectroscopy. Proceedings of the National Academy of Sciences of the United States of America. 107: 11336-40. PMID 20534507 DOI: 10.1073/Pnas.1006517107  0.708
2010 Berkovich R, Garcia-Manyes S, Urbakh M, Klafter J, Fernandez JM. Collapse dynamics of single proteins extended by force. Biophysical Journal. 98: 2692-701. PMID 20513414 DOI: 10.1016/J.Bpj.2010.02.053  0.739
2010 Garcia-Manyes S, Sanz F. Nanomechanics of lipid bilayers by force spectroscopy with AFM: a perspective. Biochimica Et Biophysica Acta. 1798: 741-9. PMID 20044974 DOI: 10.1016/J.Bbamem.2009.12.019  0.378
2009 Garcia-Manyes S, Liang J, Szoszkiewicz R, Kuo TL, Fernández JM. Force-activated reactivity switch in a bimolecular chemical reaction. Nature Chemistry. 1: 236-42. PMID 21378854 DOI: 10.1038/Nchem.207  0.72
2009 Grützner A, Garcia-Manyes S, Kötter S, Badilla CL, Fernandez JM, Linke WA. Modulation of titin-based stiffness by disulfide bonding in the cardiac titin N2-B unique sequence. Biophysical Journal. 97: 825-34. PMID 19651040 DOI: 10.1016/J.Bpj.2009.05.037  0.617
2009 Garcia-Manyes S, Dougan L, Badilla CL, Brujic J, Fernández JM. Direct observation of an ensemble of stable collapsed states in the mechanical folding of ubiquitin. Proceedings of the National Academy of Sciences of the United States of America. 106: 10534-9. PMID 19541635 DOI: 10.1073/Pnas.0901213106  0.806
2009 Garcia-Manyes S, Dougan L, Fernández JM. Osmolyte-induced separation of the mechanical folding phases of ubiquitin. Proceedings of the National Academy of Sciences of the United States of America. 106: 10540-5. PMID 19541633 DOI: 10.1073/Pnas.0902090106  0.797
2009 Liu R, Garcia-Manyes S, Sarkar A, Badilla CL, Fernández JM. Mechanical characterization of protein L in the low-force regime by electromagnetic tweezers/evanescent nanometry. Biophysical Journal. 96: 3810-21. PMID 19413987 DOI: 10.1016/J.Bpj.2009.01.043  0.749
2009 Liu R, Garcia-Manyes S, Sarkar A, Badilla CL, Fernandez JM. Platform AY: Emerging Single Molecule Techniques IIMechanical characterization of Protein L in the low-force regime by electromagnetic tweezers/evanescent nanometry Biophysical Journal. DOI: 10.1016/J.Bpj.2008.12.3650  0.677
2009 Garcia-Manyes S, Dougan L, Badilla CL, Brujic J, Fernandez J. Revisiting Protein Folding at the Single Molecule Level Biophysical Journal. 96: 217a. DOI: 10.1016/J.Bpj.2008.12.1903  0.8
2009 Garcia-Manyes S, Liang J, Fernandez JM. Direct Identification of Two Distinct Transition State Structures in Reduction of a Disulfide Bond Revealed by Single Bond Force-clamp Spectroscopy Biophysical Journal. 96: 37a. DOI: 10.1016/J.Bpj.2008.12.085  0.669
2007 Oncins G, Picas L, Hernández-Borrell J, Garcia-Manyes S, Sanz F. Thermal response of Langmuir-Blodgett films of dipalmitoylphosphatidylcholine studied by atomic force microscopy and force spectroscopy. Biophysical Journal. 93: 2713-25. PMID 17586574 DOI: 10.1529/Biophysj.107.110916  0.414
2007 Garcia-Manyes S, Brujić J, Badilla CL, Fernández JM. Force-clamp spectroscopy of single-protein monomers reveals the individual unfolding and folding pathways of I27 and ubiquitin. Biophysical Journal. 93: 2436-46. PMID 17545242 DOI: 10.1529/Biophysj.107.104422  0.757
2007 Garcia-Manyes S, Domènech O, Sanz F, Montero MT, Hernandez-Borrell J. Atomic force microscopy and force spectroscopy study of Langmuir-Blodgett films formed by heteroacid phospholipids of biological interest. Biochimica Et Biophysica Acta. 1768: 1190-8. PMID 17376401 DOI: 10.1016/J.Bbamem.2007.02.004  0.547
2007 Brujic J, Hermans RI, Garcia-Manyes S, Walther KA, Fernandez JM. Dwell-time distribution analysis of polyprotein unfolding using force-clamp spectroscopy. Biophysical Journal. 92: 2896-903. PMID 17259284 DOI: 10.1529/Biophysj.106.099481  0.775
2006 Perez-Jimenez R, Garcia-Manyes S, Ainavarapu SR, Fernandez JM. Mechanical unfolding pathways of the enhanced yellow fluorescent protein revealed by single molecule force spectroscopy. The Journal of Biological Chemistry. 281: 40010-4. PMID 17082195 DOI: 10.1074/Jbc.M609890200  0.783
2006 Garcia-Manyes S, Gorostiza P, Sanz F. Titration force microscopy on supported lipid bilayers. Analytical Chemistry. 78: 61-70. PMID 16383311 DOI: 10.1021/Ac0510437  0.502
2006 Garcia-Manyes S, Bucior I, Ros R, Anselmetti D, Sanz F, Burger MM, Fernàndez-Busquets X. Proteoglycan mechanics studied by single-molecule force spectroscopy of allotypic cell adhesion glycans. The Journal of Biological Chemistry. 281: 5992-9. PMID 16373355 DOI: 10.1074/Jbc.M507878200  0.393
2006 Garcia-Manyes S, Oncins G, Sanz F. Effect of pH and ionic strength on phospholipid nanomechanics and on deposition process onto hydrophilic surfaces measured by AFM Electrochimica Acta. 51: 5029-5036. DOI: 10.1016/J.Electacta.2006.03.062  0.38
2005 Garcia-Manyes S, Güell AG, Gorostiza P, Sanz F. Nanomechanics of silicon surfaces with atomic force microscopy: an insight to the first stages of plastic deformation. The Journal of Chemical Physics. 123: 114711. PMID 16392587 DOI: 10.1063/1.2035094  0.446
2005 Garcia-Manyes S, Oncins G, Sanz F. Effect of temperature on the nanomechanics of lipid bilayers studied by force spectroscopy. Biophysical Journal. 89: 4261-74. PMID 16150966 DOI: 10.1529/Biophysj.105.065581  0.447
2005 Oncins G, Garcia-Manyes S, Sanz F. Study of frictional properties of a phospholipid bilayer in a liquid environment with lateral force microscopy as a function of NaCl concentration. Langmuir : the Acs Journal of Surfaces and Colloids. 21: 7373-9. PMID 16042468 DOI: 10.1021/La050644Q  0.48
2005 Garcia-Manyes S, Oncins G, Sanz F. Effect of ion-binding and chemical phospholipid structure on the nanomechanics of lipid bilayers studied by force spectroscopy. Biophysical Journal. 89: 1812-26. PMID 15980180 DOI: 10.1529/Biophysj.105.064030  0.402
2005 Morant C, Garcia-Manyes S, Sanz F, Sanz JM, Elizalde E. Nanotribological properties of CN/TiCN/TiN/Si multilayer as determined by AFM Nanotechnology. 16. DOI: 10.1088/0957-4484/16/5/014  0.377
2004 Garcia-Manyes S, Verdaguer A, Gorostiza P, Sanz F. Alkali halide nanocrystal growth and etching studied by AFM and modeled by MD simulations. The Journal of Chemical Physics. 120: 2963-71. PMID 15268443 DOI: 10.1063/1.1628223  0.38
2002 Fraxedas J, Garcia-Manyes S, Gorostiza P, Sanz F. Nanoindentation: Toward the sensing of atomic interactions. Proceedings of the National Academy of Sciences of the United States of America. 99: 5228-5232. PMID 16578871 DOI: 10.1073/Pnas.042106699  0.35
2002 Garcia-Manyes S, Gorostiza P, Sanz F. Nanoindentation: From forces to energies Mrs Proceedings. 738: 195-200. DOI: 10.1557/Proc-738-G6.2  0.453
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