| Year |
Citation |
Score |
| 2020 |
Mitchell EJ, Thomson DM, Openshaw RL, Bristow GC, Dawson N, Pratt JA, Morris BJ. Drug-responsive autism phenotypes in the 16p11.2 deletion mouse model: a central role for gene-environment interactions. Scientific Reports. 10: 12303. PMID 32704009 DOI: 10.1038/S41598-020-69130-8 |
0.322 |
|
| 2020 |
Mitchell EJ, Brett RR, Armstrong JD, Sillito RR, Pratt JA. Temporal dissociation of phencyclidine: Induced locomotor and social alterations in rats using an automated homecage monitoring system - implications for the 3Rs and preclinical drug discovery. Journal of Psychopharmacology (Oxford, England). 269881120920455. PMID 32438848 DOI: 10.1177/0269881120920455 |
0.304 |
|
| 2020 |
Bristow GC, Thomson DM, Openshaw RL, Mitchell EJ, Pratt JA, Dawson N, Morris BJ. 16p11 Duplication Disrupts Hippocampal-Orbitofrontal-Amygdala Connectivity, Revealing a Neural Circuit Endophenotype for Schizophrenia. Cell Reports. 31: 107536. PMID 32320645 DOI: 10.1016/J.Celrep.2020.107536 |
0.4 |
|
| 2019 |
Openshaw RL, Thomson DM, Thompson R, Penninger JM, Pratt JA, Morris BJ, Dawson N. Map2k7 Haploinsufficiency Induces Brain Imaging Endophenotypes and Behavioral Phenotypes Relevant to Schizophrenia. Schizophrenia Bulletin. PMID 31219577 DOI: 10.1093/Schbul/Sbz044 |
0.404 |
|
| 2019 |
Openshaw RL, Kwon J, McColl A, Penninger JM, Cavanagh J, Pratt JA, Morris BJ. JNK signalling mediates aspects of maternal immune activation: importance of maternal genotype in relation to schizophrenia risk. Journal of Neuroinflammation. 16: 18. PMID 30691477 DOI: 10.1186/S12974-019-1408-5 |
0.303 |
|
| 2018 |
Kouskou M, Thomson DM, Brett RR, Wheeler L, Tate RJ, Pratt JA, Chamberlain LH. Disruption of the Zdhhc9 intellectual disability gene leads to behavioural abnormalities in a mouse model. Experimental Neurology. PMID 29944857 DOI: 10.1016/J.Expneurol.2018.06.014 |
0.311 |
|
| 2018 |
Pratt JA, Morris B, Dawson N. Deconstructing Schizophrenia: Advances in Preclinical Models for Biomarker Identification. Current Topics in Behavioral Neurosciences. PMID 29721851 DOI: 10.1007/7854_2018_48 |
0.386 |
|
| 2018 |
Bristow G, Thomson D, Pratt J, Morris B, Dawson N. F41. Schizophrenia-Relevant Alterations In Cerebral Metabolism, Glutamate And Monoaminergic Neurotransmitter System Function In A Mouse Model Of 16P11.2 Duplication Schizophrenia Bulletin. 44. DOI: 10.1093/Schbul/Sby017.572 |
0.348 |
|
| 2016 |
Openshaw RL, Thomson DM, Penninger JM, Pratt JA, Morris BJ. Mice haploinsufficient for Map2k7, a gene involved in neurodevelopment and risk for schizophrenia, show impaired attention, a vigilance decrement deficit and unstable cognitive processing in an attentional task: impact of minocycline. Psychopharmacology. PMID 27774567 DOI: 10.1007/S00213-016-4463-Y |
0.316 |
|
| 2016 |
Pratt J, Dawson N, Morris BJ, Grent-'t-Jong T, Roux F, Uhlhaas PJ. Thalamo-cortical communication, glutamatergic neurotransmission and neural oscillations: A unique window into the origins of ScZ? Schizophrenia Research. PMID 27317361 DOI: 10.1016/J.Schres.2016.05.013 |
0.352 |
|
| 2015 |
Dawson N, Kurihara M, Thomson DM, Winchester CL, McVie A, Hedde JR, Randall AD, Shen S, Seymour PA, Hughes ZA, Dunlop J, Brown JT, Brandon NJ, Morris BJ, Pratt JA. Altered functional brain network connectivity and glutamate system function in transgenic mice expressing truncated Disrupted-in-Schizophrenia 1. Translational Psychiatry. 5: e569. PMID 25989143 DOI: 10.1038/Tp.2015.60 |
0.37 |
|
| 2015 |
Pratt J. Schizophrenia in the 21st century: new insights and translation into improved therapies. Journal of Psychopharmacology (Oxford, England). 29: 83-4. PMID 25650373 DOI: 10.1177/0269881114566743 |
0.382 |
|
| 2015 |
Pratt JA, Morris BJ. The thalamic reticular nucleus: a functional hub for thalamocortical network dysfunction in schizophrenia and a target for drug discovery. Journal of Psychopharmacology (Oxford, England). 29: 127-37. PMID 25586397 DOI: 10.1177/0269881114565805 |
0.402 |
|
| 2015 |
Dawson N, Morris BJ, Pratt JA. Functional brain connectivity phenotypes for schizophrenia drug discovery. Journal of Psychopharmacology (Oxford, England). 29: 169-77. PMID 25567554 DOI: 10.1177/0269881114563635 |
0.407 |
|
| 2014 |
Morris BJ, Pratt JA. Novel treatment strategies for schizophrenia from improved understanding of genetic risk. Clinical Genetics. 86: 401-11. PMID 25142969 DOI: 10.1111/Cge.12485 |
0.347 |
|
| 2014 |
Winchester CL, Pratt JA, Morris BJ. Risk genes for schizophrenia: translational opportunities for drug discovery. Pharmacology & Therapeutics. 143: 34-50. PMID 24561132 DOI: 10.1016/J.Pharmthera.2014.02.003 |
0.377 |
|
| 2014 |
Dawson N, McDonald M, Higham DJ, Morris BJ, Pratt JA. Subanesthetic ketamine treatment promotes abnormal interactions between neural subsystems and alters the properties of functional brain networks. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 39: 1786-98. PMID 24492765 DOI: 10.1038/Npp.2014.26 |
0.438 |
|
| 2014 |
Dawson N, Xiao X, McDonald M, Higham DJ, Morris BJ, Pratt JA. Sustained NMDA receptor hypofunction induces compromised neural systems integration and schizophrenia-like alterations in functional brain networks. Cerebral Cortex (New York, N.Y. : 1991). 24: 452-64. PMID 23081884 DOI: 10.1093/Cercor/Bhs322 |
0.419 |
|
| 2013 |
Ewing SG, Porr B, Pratt JA. Deep brain stimulation of the mediodorsal thalamic nucleus yields increases in the expression of zif-268 but not c-fos in the frontal cortex. Journal of Chemical Neuroanatomy. 52: 20-4. PMID 23660497 DOI: 10.1016/J.Jchemneu.2013.04.002 |
0.335 |
|
| 2013 |
Dawson N, Morris BJ, Pratt JA. Subanaesthetic ketamine treatment alters prefrontal cortex connectivity with thalamus and ascending subcortical systems. Schizophrenia Bulletin. 39: 366-77. PMID 22114100 DOI: 10.1093/Schbul/Sbr144 |
0.44 |
|
| 2012 |
Winchester CL, Ohzeki H, Vouyiouklis DA, Thompson R, Penninger JM, Yamagami K, Norrie JD, Hunter R, Pratt JA, Morris BJ. Converging evidence that sequence variations in the novel candidate gene MAP2K7 (MKK7) are functionally associated with schizophrenia. Human Molecular Genetics. 21: 4910-21. PMID 22899651 DOI: 10.1093/Hmg/Dds331 |
0.403 |
|
| 2012 |
Pratt J, Winchester C, Dawson N, Morris B. Advancing schizophrenia drug discovery: optimizing rodent models to bridge the translational gap. Nature Reviews. Drug Discovery. 11: 560-79. PMID 22722532 DOI: 10.1038/Nrd3649 |
0.368 |
|
| 2012 |
Steward LJ, Kennedy MD, Morris BJ, Pratt JA. Chronic phencyclidine (PCP)-induced modulation of muscarinic receptor mRNAs in rat brain: impact of antipsychotic drug treatment. Neuropharmacology. 62: 1554-63. PMID 21640736 DOI: 10.1016/J.Neuropharm.2011.05.016 |
0.387 |
|
| 2012 |
Dawson N, Thompson RJ, McVie A, Thomson DM, Morris BJ, Pratt JA. Modafinil reverses phencyclidine-induced deficits in cognitive flexibility, cerebral metabolism, and functional brain connectivity. Schizophrenia Bulletin. 38: 457-74. PMID 20810469 DOI: 10.1093/Schbul/Sbq090 |
0.394 |
|
| 2012 |
Stenson GM, Pratt JA, Brett RR. Poster #15 ENVIRONMENT-ENVIRONMENT INTERACTIONS IN A SCHIZOPHRENIA-RELATED DISEASE MODEL: IMPACT OF POLY IC AND THC ON THE DEVELOPING BRAIN Schizophrenia Research. 136. DOI: 10.1016/S0920-9964(12)70848-4 |
0.332 |
|
| 2012 |
Lee G, Thomson DM, McVie A, Suckling CJ, Morris BJ, Pratt JA. Poster #128 NITRIC OXIDE SYNTHASE ACTIVITY IS DIFFERENTIALLY ALTERED BETWEEN ACUTE AND SUBCHRONIC PHENCYCLIDINE TREATMENTS IN DISCRETE MOUSE BRAIN REGIONS Schizophrenia Research. 136: S137-S138. DOI: 10.1016/S0920-9964(12)70442-5 |
0.467 |
|
| 2012 |
Dawson N, Thomson DM, Morris BJ, Pratt JA. Poster #14 NEURAL SYSTEMS UNDERLYING SCHIZOPHRENIA-RELATED BEHAVIOURAL PHENOTYPES IN MICE Schizophrenia Research. 136. DOI: 10.1016/S0920-9964(12)70330-4 |
0.349 |
|
| 2011 |
Sousa VC, Assaife-Lopes N, Ribeiro JA, Pratt JA, Brett RR, Sebastião AM. Regulation of hippocampal cannabinoid CB1 receptor actions by adenosine A1 receptors and chronic caffeine administration: implications for the effects of Δ9-tetrahydrocannabinol on spatial memory. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 36: 472-87. PMID 20927050 DOI: 10.1038/Npp.2010.179 |
0.33 |
|
| 2011 |
Thomson DM, McVie A, Morris BJ, Pratt JA. Dissociation of acute and chronic intermittent phencyclidine-induced performance deficits in the 5-choice serial reaction time task: influence of clozapine. Psychopharmacology. 213: 681-95. PMID 20878519 DOI: 10.1007/S00213-010-2020-7 |
0.414 |
|
| 2010 |
Pratt JA, Dawson N, Winchester CL, Thomson DM, Morris BJ. Distinct Aspects Of Prefrontal Cortex Dysfunction In Schizophrenia Modelled By Acute And Repeated Pcp Treatment: Impact Of Modafinil Schizophrenia Research. 117: 509-509. DOI: 10.1016/J.Schres.2010.02.972 |
0.381 |
|
| 2010 |
Ewing SG, Pratt JA. DEEP BRAIN STIMULATION OF THE MEDIODORSAL THALAMIC NUCLEUS AND ITS IMPLICATIONS FOR THE TREATMENT OF SCHIZOPHRENIA Schizophrenia Research. 117: 277-278. DOI: 10.1016/J.Schres.2010.02.449 |
0.38 |
|
| 2010 |
Dawson N, Higham D, Pratt J, Morris B. Alterations in functional brain network structure induced by subchronic phencyclidine (PCP) treatment parallel those seen in schizophrenia Schizophrenia Research. 117: 234-235. DOI: 10.1016/J.Schres.2010.02.349 |
0.399 |
|
| 2008 |
Egerton A, Reid L, McGregor S, Cochran SM, Morris BJ, Pratt JA. Subchronic and chronic PCP treatment produces temporally distinct deficits in attentional set shifting and prepulse inhibition in rats. Psychopharmacology. 198: 37-49. PMID 18427784 DOI: 10.1007/S00213-008-1071-5 |
0.378 |
|
| 2008 |
Pratt JA, Winchester C, Egerton A, Cochran SM, Morris BJ. Modelling prefrontal cortex deficits in schizophrenia: implications for treatment. British Journal of Pharmacology. 153: S465-70. PMID 18311160 DOI: 10.1038/Bjp.2008.24 |
0.442 |
|
| 2008 |
Winchester C, Thomson D, Morris B, Pratt J. Alternative Approach To Modulating Schizophrenia-Associated Genes In The Rodent Brain Schizophrenia Research. 102: 67. DOI: 10.1016/S0920-9964(08)70208-1 |
0.369 |
|
| 2007 |
Suckling CJ, Murphy JA, Khalaf AI, Zhou SZ, Lizos DE, van Nhien AN, Yasumatsu H, McVie A, Young LC, McCraw C, Waterman PG, Morris BJ, Pratt JA, Harvey AL. M4 agonists/5HT7 antagonists with potential as antischizophrenic drugs: serominic compounds. Bioorganic & Medicinal Chemistry Letters. 17: 2649-55. PMID 17317171 DOI: 10.1016/J.Bmcl.2007.01.093 |
0.363 |
|
| 2006 |
Egerton A, Allison C, Brett RR, Pratt JA. Cannabinoids and prefrontal cortical function: insights from preclinical studies. Neuroscience and Biobehavioral Reviews. 30: 680-95. PMID 16574226 DOI: 10.1016/J.Neubiorev.2005.12.002 |
0.333 |
|
| 2006 |
Paterson GJ, Ohashi Y, Reynolds GP, Pratt JA, Morris BJ. Selective increases in the cytokine, TNFalpha, in the prefrontal cortex of PCP-treated rats and human schizophrenic subjects: influence of antipsychotic drugs. Journal of Psychopharmacology (Oxford, England). 20: 636-42. PMID 16478754 DOI: 10.1177/0269881106062025 |
0.366 |
|
| 2005 |
Egerton A, Brett RR, Pratt JA. Acute delta9-tetrahydrocannabinol-induced deficits in reversal learning: neural correlates of affective inflexibility. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 30: 1895-905. PMID 15812570 DOI: 10.1038/Sj.Npp.1300715 |
0.358 |
|
| 2005 |
Allison C, Pratt JA, Ripley TL, Stephens DN. alpha-Amino-3-hydroxy-5-methylisoxazole-4-propionate receptor autoradiography in mouse brain after single and repeated withdrawal from diazepam. The European Journal of Neuroscience. 21: 1045-56. PMID 15787709 DOI: 10.1111/J.1460-9568.2005.03902.X |
0.359 |
|
| 2005 |
Egerton A, Reid L, McKerchar CE, Morris BJ, Pratt JA. Impairment in perceptual attentional set-shifting following PCP administration: a rodent model of set-shifting deficits in schizophrenia. Psychopharmacology. 179: 77-84. PMID 15682304 DOI: 10.1007/S00213-004-2109-Y |
0.387 |
|
| 2005 |
Morris BJ, Cochran SM, Pratt JA. PCP: from pharmacology to modelling schizophrenia. Current Opinion in Pharmacology. 5: 101-6. PMID 15661633 DOI: 10.1016/J.Coph.2004.08.008 |
0.425 |
|
| 2005 |
Reynolds LM, Cochran SM, Morris BJ, Pratt JA, Reynolds GP. Chronic phencyclidine administration induces schizophrenia-like changes in N-acetylaspartate and N-acetylaspartylglutamate in rat brain. Schizophrenia Research. 73: 147-52. PMID 15653257 DOI: 10.1016/J.Schres.2004.02.003 |
0.416 |
|
| 2004 |
Steward LJ, Kennedy MD, Morris BJ, Pratt JA. The atypical antipsychotic drug clozapine enhances chronic PCP-induced regulation of prefrontal cortex 5-HT2A receptors. Neuropharmacology. 47: 527-37. PMID 15380371 DOI: 10.1016/J.Neuropharm.2004.04.020 |
0.421 |
|
| 2003 |
Allison C, Pratt JA. Neuroadaptive processes in GABAergic and glutamatergic systems in benzodiazepine dependence. Pharmacology & Therapeutics. 98: 171-95. PMID 12725868 DOI: 10.1016/S0163-7258(03)00029-9 |
0.333 |
|
| 2003 |
Cochran SM, Kennedy M, McKerchar CE, Steward LJ, Pratt JA, Morris BJ. Induction of metabolic hypofunction and neurochemical deficits after chronic intermittent exposure to phencyclidine: differential modulation by antipsychotic drugs. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 28: 265-75. PMID 12589379 DOI: 10.1038/Sj.Npp.1300031 |
0.319 |
|
| 2002 |
Cochran SM, Fujimura M, Morris BJ, Pratt JA. Acute and delayed effects of phencyclidine upon mRNA levels of markers of glutamatergic and GABAergic neurotransmitter function in the rat brain. Synapse (New York, N.Y.). 46: 206-14. PMID 12325047 DOI: 10.1002/Syn.10126 |
0.395 |
|
| 2002 |
Cochran SM, McKerchar CE, Morris BJ, Pratt JA. Induction of differential patterns of local cerebral glucose metabolism and immediate-early genes by acute clozapine and haloperidol. Neuropharmacology. 43: 394-407. PMID 12243769 DOI: 10.1016/S0028-3908(02)00091-6 |
0.393 |
|
| 2002 |
Gholamreza P, Pratt JA, Nima D. Effects of low-dose scopolamine on locomotor activity: No dissociation between cognitive and non-cognitive effects Neuroscience Research Communications. 31: 165-174. DOI: 10.1002/Nrc.10049 |
0.315 |
|
| 2001 |
Brett R, MacKenzie F, Pratt J. Δ9-tetrahydrocannabinol-induced alterations in limbic system glucose use in the rat Neuroreport. 12: 3573-3577. PMID 11733714 DOI: 10.1097/00001756-200111160-00040 |
0.326 |
|
| 2001 |
Cochran SM, Harvey AL, Pratt JA. Regionally selective alterations in local cerebral glucose utilization evoked by charybdotoxin, a blocker of central voltage-activated K+-channels. The European Journal of Neuroscience. 14: 1455-63. PMID 11722607 DOI: 10.1046/J.0953-816X.2001.01770.X |
0.349 |
|
| 2000 |
Kempsill FE, Pratt JA. Mecamylamine but not the alpha7 receptor antagonist alpha-bungarotoxin blocks sensitization to the locomotor stimulant effects of nicotine. British Journal of Pharmacology. 131: 997-1003. PMID 11053222 DOI: 10.1038/Sj.Bjp.0703560 |
0.321 |
|
| 1999 |
Gray A, Allison C, Pratt JA. A role for AMPA/kainate receptors in conditioned place preference induced by diazepam in the rat. Neuroscience Letters. 268: 127-30. PMID 10406021 DOI: 10.1016/S0304-3940(99)00371-7 |
0.341 |
|
| 1998 |
Harvey AL, Bradley KN, Cochran SA, Rowan EG, Pratt JA, Quillfeldt JA, Jerusalinsky DA. What can toxins tell us for drug discovery? Toxicon : Official Journal of the International Society On Toxinology. 36: 1635-40. PMID 9792180 DOI: 10.1016/S0041-0101(98)00156-1 |
0.338 |
|
| 1998 |
Pratt JA, Brett RR, Laurie DJ. Benzodiazepine dependence: from neural circuits to gene expression. Pharmacology, Biochemistry, and Behavior. 59: 925-34. PMID 9586850 DOI: 10.1016/S0091-3057(97)00539-X |
0.364 |
|
| 1995 |
Brett RR, Pratt JA. Changes in benzodiazepine-GABA receptor coupling in an accumbens-habenula circuit after chronic diazepam treatment. British Journal of Pharmacology. 116: 2375-84. PMID 8581272 DOI: 10.1111/J.1476-5381.1995.Tb15083.X |
0.32 |
|
| 1995 |
French N, Lalies MD, Nutt DJ, Pratt JA. Idazoxan-induced reductions in cortical glucose use are accompanied by an increase in noradrenaline release: complementary [14C]2-deoxyglucose and microdialysis studies. Neuropharmacology. 34: 605-13. PMID 7566496 DOI: 10.1016/0028-3908(95)00031-Z |
0.317 |
|
| 1993 |
Laurie DJ, Pratt JA. Flumazenil induces localised increases in glucose utilization during diazepam withdrawal in rats. Brain Research. 631: 277-86. PMID 8131056 DOI: 10.1016/0006-8993(93)91546-5 |
0.36 |
|
| 1992 |
Pratt JA. The neuroanatomical basis of anxiety. Pharmacology & Therapeutics. 55: 149-81. PMID 1363249 DOI: 10.1016/0163-7258(92)90014-Q |
0.31 |
|
| 1991 |
Mitchell EA, Pratt JA. Neuroanatomical structures involved in the action of the 5-HT3 antagonist ondansetron: a 2-deoxyglucose autoradiographic study in the rat. Brain Research. 538: 289-94. PMID 1826459 DOI: 10.1016/0006-8993(91)90442-X |
0.322 |
|
| 1991 |
Brett RR, Pratt JA. Muscimol-associated changes in local cerebral glucose use following chronic diazepam administration. Brain Research. 558: 280-8. PMID 1782545 DOI: 10.1016/0006-8993(91)90779-U |
0.351 |
|
| 1989 |
Laurie DJ, Pratt JA. Local cerebral glucose utilization following subacute and chronic diazepam pretreatment: differential tolerance. Brain Research. 504: 101-11. PMID 2598004 DOI: 10.1016/0006-8993(89)91603-X |
0.357 |
|
| 1988 |
Pratt JA, Laurie DJ, McCulloch J. The effects of FG 7142 upon local cerebral glucose utilization suggest overlap between limbic structures important in anxiety and convulsions. Brain Research. 475: 218-31. PMID 3214732 DOI: 10.1016/0006-8993(88)90610-5 |
0.324 |
|
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