Forest M. White, Ph.D. - Publications

Affiliations: 
Biological Engineering Massachusetts Institute of Technology, Cambridge, MA, United States 
Area:
protein phosphorylation, signal transduction cascades
Website:
http://web.mit.edu/fwhitelab/

105 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Gerritsen J, Rizzo S, Thévenin D, White FM. System-Level Analysis of the Effects of RPTPs on Cellular Signaling Networks. Methods in Molecular Biology (Clifton, N.J.). 2743: 153-163. PMID 38147214 DOI: 10.1007/978-1-0716-3569-8_10  0.324
2022 Rizzo S, Sikorski E, Hart W, Gerristen J, Lazzarra M, White F, Thévenin D. Development of Tumor-selective Transmembrane Peptides to Promote the Activity of the Receptor Protein Tyrosine Phosphatase J by Disrupting its Homodimerization. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 35552736 DOI: 10.1096/fasebj.2022.36.S1.R3882  0.326
2021 Stopfer LE, Flower CT, Gajadhar AS, Patel B, Gallien S, Lopez-Ferrer D, White FM. High-density, targeted monitoring of tyrosine phosphorylation reveals activated signaling networks in human tumors. Cancer Research. PMID 33509940 DOI: 10.1158/0008-5472.CAN-20-3804  0.337
2020 Stopfer LE, Mesfin JM, Joughin BA, Lauffenburger DA, White FM. Multiplexed relative and absolute quantitative immunopeptidomics reveals MHC I repertoire alterations induced by CDK4/6 inhibition. Nature Communications. 11: 2760. PMID 32488085 DOI: 10.1038/S41467-020-16588-9  0.312
2019 Randall EC, Lopez BGC, Peng S, Regan MS, Abdelmoula WM, Basu SS, Santagata S, Yoon H, Haigis M, Agar JN, Tran NL, Elmquist WF, White FM, Sarkaria JN, Agar NYR. Localized metabolomic gradients in patient-derived xenograft models of glioblastoma. Cancer Research. PMID 31767628 DOI: 10.1158/0008-5472.Can-19-0638  0.337
2019 Dittmann A, Kennedy NJ, Soltero NL, Morshed N, Mana MD, Yilmaz ÖH, Davis RJ, White FM. High-fat diet in a mouse insulin-resistant model induces widespread rewiring of the phosphotyrosine signaling network. Molecular Systems Biology. 15: e8849. PMID 31464373 DOI: 10.15252/Msb.20198849  0.358
2019 Jaeger AM, Stopfer L, Lee S, Gaglia G, Sandel D, Santagata S, Lin NU, Trepel JB, White FM, Jacks T, Lindquist S, Whitesell L. Rebalancing protein homeostasis enhances tumor antigen presentation. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 31213460 DOI: 10.1158/1078-0432.Ccr-19-0596  0.332
2019 Del Rosario BC, Kriz AJ, Del Rosario AM, Anselmo A, Frye CJ, White FM, Sadreyev RI, Lee JT. Exploration of CTCF post-translation modifications uncovers Serine-224 phosphorylation by PLK1 at pericentric regions during the G2/M transition. Elife. 8. PMID 30676316 DOI: 10.7554/Elife.42341  0.633
2019 Schwill M, Tamaskovic R, Gajadhar AS, Kast F, White FM, Plückthun A. Systemic analysis of tyrosine kinase signaling reveals a common adaptive response program in a HER2-positive breast cancer. Science Signaling. 12. PMID 30670633 DOI: 10.1126/Scisignal.Aau2875  0.437
2018 Rothenberg DA, Taliaferro JM, Huber SM, Begley TJ, Dedon PC, White FM. A Proteomics Approach to Profiling the Temporal Translational Response to Stress and Growth. Iscience. 9: 367-381. PMID 30466063 DOI: 10.1016/J.Isci.2018.11.004  0.306
2018 Randall EC, Emdal KB, Laramy JK, Kim M, Roos A, Calligaris D, Regan MS, Gupta SK, Mladek AC, Carlson BL, Johnson AJ, Lu FK, Xie XS, Joughin BA, Reddy RJ, ... ... White FM, et al. Integrated mapping of pharmacokinetics and pharmacodynamics in a patient-derived xenograft model of glioblastoma. Nature Communications. 9: 4904. PMID 30464169 DOI: 10.1038/S41467-018-07334-3  0.33
2018 Aebersold R, Agar JN, Amster IJ, Baker MS, Bertozzi CR, Boja ES, Costello CE, Cravatt BF, Fenselau C, Garcia BA, Ge Y, Gunawardena J, Hendrickson RC, Hergenrother PJ, Huber CG, ... ... White FM, et al. How many human proteoforms are there? Nature Chemical Biology. 14: 206-214. PMID 29443976 DOI: 10.1038/Nchembio.2576  0.327
2018 Johnson H, White FM. Quantitative Analysis of Tyrosine Kinase Signaling Across Differentially Embedded Human Glioblastoma Tumors. Methods in Molecular Biology (Clifton, N.J.). 1711: 149-164. PMID 29344889 DOI: 10.1007/978-1-4939-7493-1_8  0.603
2018 Flashner-Abramson E, Abramson J, White FM, Kravchenko-Balasha N. A thermodynamic-based approach for the resolution and prediction of protein network structures Chemical Physics. 514: 20-30. DOI: 10.1016/J.Chemphys.2018.03.005  0.368
2017 Liu H, Murphy CJ, Karreth FA, Emdal KB, White FM, Elemento O, Toker A, Wulf GM, Cantley LC. Identifying and Targeting Sporadic Oncogenic Genetic Aberrations in Mouse Models of Triple Negative Breast Cancer. Cancer Discovery. PMID 29203461 DOI: 10.1158/2159-8290.Cd-17-0679  0.333
2017 Jadwin JA, Curran TG, Lafontaine AT, White FM, Mayer BJ. Src Homology 2 domains enhance tyrosine phosphorylation in vivo by protecting binding sites in their target proteins from dephosphorylation. The Journal of Biological Chemistry. PMID 29162725 DOI: 10.1074/Jbc.M117.794412  0.363
2017 Emdal KB, Dittmann A, Reddy RJ, Lescarbeau RS, Moores SL, Laquerre S, White FM. Characterization of in vivo resistance to osimertinib and JNJ-61186372, an EGFR/Met bi-specific antibody, reveals unique and consensus mechanisms of resistance. Molecular Cancer Therapeutics. PMID 28830985 DOI: 10.1158/1535-7163.Mct-17-0413  0.388
2017 Valdez J, Cook CD, Ahrens CC, Wang AJ, Brown A, Kumar M, Stockdale L, Rothenberg D, Renggli K, Gordon E, Lauffenburger D, White F, Griffith L. On-demand dissolution of modular, synthetic extracellular matrix reveals local epithelial-stromal communication networks. Biomaterials. 130: 90-103. PMID 28371736 DOI: 10.1016/J.Biomaterials.2017.03.030  0.354
2016 Pirhaji L, Milani P, Leidl M, Curran T, Avila-Pacheco J, Clish CB, White FM, Saghatelian A, Fraenkel E. Revealing disease-associated pathways by network integration of untargeted metabolomics. Nature Methods. PMID 27479327 DOI: 10.1038/Nmeth.3940  0.336
2016 Tuncbag N, Milani P, Pokorny JL, Johnson H, Sio TT, Dalin S, Iyekegbe DO, White FM, Sarkaria JN, Fraenkel E. Network Modeling Identifies Patient-specific Pathways in Glioblastoma. Scientific Reports. 6: 28668. PMID 27354287 DOI: 10.1038/Srep28668  0.581
2016 Lescarbeau RS, Lei L, Bakken KK, Sims PA, Sarkaria JN, Canoll P, White FM. Quantitative Phosphoproteomics Reveals Wee1 Kinase as a Therapeutic Target in a Model of Proneural Glioblastoma. Molecular Cancer Therapeutics. PMID 27196784 DOI: 10.1158/1535-7163.MCT-15-0692-T  0.314
2016 Jadwin JA, Oh D, Curran TG, Ogiue-Ikeda M, Jia L, White FM, Machida K, Yu J, Mayer BJ. Time-resolved multimodal analysis of Src Homology 2 (SH2) domain binding in signaling by receptor tyrosine kinases. Elife. 5. PMID 27071344 DOI: 10.7554/Elife.11835  0.351
2016 White FM, Wolf-Yadlin A. Methods for the Analysis of Protein Phosphorylation-Mediated Cellular Signaling Networks. Annual Review of Analytical Chemistry (Palo Alto, Calif.). PMID 27049636 DOI: 10.1146/Annurev-Anchem-071015-041542  0.419
2016 Kravchenko-Balasha N, Johnson H, White FM, Heath JR, Levine RD. A Thermodynamic Based Interpretation of Protein Expression Heterogeneity in Different GBM Tumors Identifies Tumor Specific Unbalanced Processes. The Journal of Physical Chemistry. B. PMID 27035264 DOI: 10.1021/Acs.Jpcb.6B01692  0.536
2016 Lescarbeau RS, Lei L, Bakken KK, Sims PA, Sarkaria JN, Canoll P, White FM. Quantitative phosphoproteomics reveals Wee1 kinase as a therapeutic target in a model of proneural glioblastoma. Molecular Cancer Therapeutics. PMID 27009214 DOI: 10.1158/1535-7163.Mct-15-0692-T  0.422
2016 Reddy RJ, Gajadhar AS, Swenson EJ, Rothenberg DA, Curran TG, White FM. Early signaling dynamics of the epidermal growth factor receptor. Proceedings of the National Academy of Sciences of the United States of America. PMID 26929352 DOI: 10.1073/Pnas.1521288113  0.435
2016 Reddy RJ, Curran TG, Zhang Y, White FM. Measurement of Phosphorylated Peptides with Absolute Quantification. Methods in Molecular Biology (Clifton, N.J.). 1410: 281-92. PMID 26867751 DOI: 10.1007/978-1-4939-3524-6_17  0.345
2016 Rothenberg DA, Gordon EA, White FM, Lourido S. Identification of Direct Kinase Substrates Using Analogue-Sensitive Alleles. Methods in Molecular Biology (Clifton, N.J.). 1355: 71-84. PMID 26584919 DOI: 10.1007/978-1-4939-3049-4_5  0.391
2016 Jadwin JA, Oh D, Curran TG, Ogiue-Ikeda M, Jia L, White FM, Machida K, Yu J, Mayer BJ. Author response: Time-resolved multimodal analysis of Src Homology 2 (SH2) domain binding in signaling by receptor tyrosine kinases Elife. DOI: 10.7554/Elife.11835.028  0.347
2015 Hughes SK, Oudin MJ, Tadros J, Neil J, Del Rosario A, Joughin BA, Ritsma L, Wyckoff J, Vasile E, Eddy R, Philippar U, Lussiez A, Condeelis JS, van Rheenen J, White F, et al. PTP1B-dependent regulation of receptor tyrosine kinase signaling by the actin-binding protein Mena. Molecular Biology of the Cell. PMID 26337385 DOI: 10.1091/Mbc.E15-06-0442  0.666
2015 McFaline-Figueroa JL, Braun CJ, Stanciu M, Nagel ZD, Mazzucato P, Sangaraju D, Cerniauskas E, Barford K, Vargas A, Chen Y, Tretyakova N, Lees JA, Hemann MT, White FM, Samson LD. Minor Changes in Expression of the Mismatch Repair Protein MSH2 Exert a Major Impact on Glioblastoma Response to Temozolomide. Cancer Research. PMID 26025730 DOI: 10.1158/0008-5472.Can-14-3616  0.324
2015 Bryson BD, White FM. Quantitative Profiling of Lysine Acetylation Reveals Dynamic Crosstalk between Receptor Tyrosine Kinases and Lysine Acetylation. Plos One. 10: e0126242. PMID 25978619 DOI: 10.1371/Journal.Pone.0126242  0.413
2015 Gajadhar AS, Johnson H, Slebos RJ, Shaddox K, Wiles K, Washington MK, Herline AJ, Levine DA, Liebler DC, White FM. Phosphotyrosine signaling analysis in human tumors is confounded by systemic ischemia-driven artifacts and intra-specimen heterogeneity. Cancer Research. 75: 1495-503. PMID 25670172 DOI: 10.1158/0008-5472.Can-14-2309  0.576
2015 Bryson BD, Del Rosario AM, Gootenberg JS, Yaffe MB, White FM. Engineered bromodomains to explore the acetylproteome. Proteomics. 15: 1470-5. PMID 25641834 DOI: 10.1002/Pmic.201400401  0.63
2015 Curran TG, Zhang Y, Ma DJ, Sarkaria JN, White FM. MARQUIS: a multiplex method for absolute quantification of peptides and posttranslational modifications. Nature Communications. 6: 5924. PMID 25581283 DOI: 10.1038/Ncomms6924  0.43
2015 Shah AK, Sachdew V, Taylor-Parker J, Tapan U, Tohme YH, Malinkovich Y, Tran B, Gibbs P, Salgia R, White FM, Parvin J, Bharti A. Effect of DNA-PK dependent phosphorylation of topo-I-S10 on its rate of proteasomal degradation and CPT response. Journal of Clinical Oncology. 33: 606-606. DOI: 10.1200/Jco.2015.33.3_Suppl.606  0.341
2015 Sarma K, Cifuentes-Rojas C, Ergun A, Del Rosario A, Jeon Y, White F, Sadreyev R, Lee JT. ATRX directs binding of PRC2 to Xist RNA and polycomb targets Cell. 160: 568-569. DOI: 10.1016/j.cell.2015.01.030  0.542
2014 Sarma K, Cifuentes-Rojas C, Ergun A, Del Rosario A, Jeon Y, White F, Sadreyev R, Lee JT. ATRX Directs Binding of PRC2 to Xist RNA and Polycomb Targets. Cell. 159: 1228. PMID 28898627 DOI: 10.1016/j.cell.2014.11.010  0.542
2014 Sarma K, Cifuentes-Rojas C, Ergun A, Del Rosario A, Jeon Y, White F, Sadreyev R, Lee JT. ATRX directs binding of PRC2 to Xist RNA and Polycomb targets. Cell. 159: 869-83. PMID 25417162 DOI: 10.1016/J.Cell.2014.10.019  0.598
2014 Bell EL, Nagamori I, Williams EO, Del Rosario AM, Bryson BD, Watson N, White FM, Sassone-Corsi P, Guarente L. SirT1 is required in the male germ cell for differentiation and fecundity in mice. Development (Cambridge, England). 141: 3495-504. PMID 25142464 DOI: 10.1242/Dev.110627  0.59
2014 Haley J, White FM. Adaptive protein and phosphoprotein networks which promote therapeutic sensitivity or acquired resistance. Biochemical Society Transactions. 42: 758-64. PMID 25109954 DOI: 10.1042/Bst20140038  0.371
2014 Johnson H, White FM. Quantitative analysis of signaling networks across differentially embedded tumors highlights interpatient heterogeneity in human glioblastoma. Journal of Proteome Research. 13: 4581-93. PMID 24927040 DOI: 10.1021/Pr500418W  0.586
2014 Mertins P, Yang F, Liu T, Mani DR, Petyuk VA, Gillette MA, Clauser KR, Qiao JW, Gritsenko MA, Moore RJ, Levine DA, Townsend R, Erdmann-Gilmore P, Snider JE, Davies SR, ... ... White F, et al. Ischemia in tumors induces early and sustained phosphorylation changes in stress kinase pathways but does not affect global protein levels. Molecular & Cellular Proteomics : McP. 13: 1690-704. PMID 24719451 DOI: 10.1074/Mcp.M113.036392  0.382
2014 Gajadhar AS, White FM. System level dynamics of post-translational modifications. Current Opinion in Biotechnology. 28: 83-7. PMID 24441143 DOI: 10.1016/J.Copbio.2013.12.009  0.382
2014 Arneja A, Johnson H, Gabrovsek L, Lauffenburger DA, White FM. Qualitatively different T cell phenotypic responses to IL-2 versus IL-15 are unified by identical dependences on receptor signal strength and duration. Journal of Immunology (Baltimore, Md. : 1950). 192: 123-35. PMID 24298013 DOI: 10.4049/Jimmunol.1302291  0.491
2013 Berchowitz LE, Gajadhar AS, van Werven FJ, De Rosa AA, Samoylova ML, Brar GA, Xu Y, Xiao C, Futcher B, Weissman JS, White FM, Amon A. A developmentally regulated translational control pathway establishes the meiotic chromosome segregation pattern. Genes & Development. 27: 2147-63. PMID 24115771 DOI: 10.1101/Gad.224253.113  0.319
2013 Floyd SR, Pacold ME, Huang Q, Clarke SM, Lam FC, Cannell IG, Bryson BD, Rameseder J, Lee MJ, Blake EJ, Fydrych A, Ho R, Greenberger BA, Chen GC, Maffa A, ... ... White FM, et al. The bromodomain protein Brd4 insulates chromatin from DNA damage signalling. Nature. 498: 246-50. PMID 23728299 DOI: 10.1038/Nature12147  0.598
2013 Miraldi ER, Sharfi H, Friedline RH, Johnson H, Zhang T, Lau KS, Ko HJ, Curran TG, Haigis KM, Yaffe MB, Bonneau R, Lauffenburger DA, Kahn BB, Kim JK, Neel BG, ... ... White FM, et al. Molecular network analysis of phosphotyrosine and lipid metabolism in hepatic PTP1b deletion mice. Integrative Biology : Quantitative Biosciences From Nano to Macro. 5: 940-63. PMID 23685806 DOI: 10.1039/C3Ib40013A  0.512
2013 Curran TG, Bryson BD, Reigelhaupt M, Johnson H, White FM. Computer aided manual validation of mass spectrometry-based proteomic data. Methods (San Diego, Calif.). 61: 219-26. PMID 23500044 DOI: 10.1016/J.Ymeth.2013.03.004  0.52
2013 Johnson H, Lescarbeau RS, Gutierrez JA, White FM. Phosphotyrosine profiling of NSCLC cells in response to EGF and HGF reveals network specific mediators of invasion. Journal of Proteome Research. 12: 1856-67. PMID 23438512 DOI: 10.1021/Pr301192T  0.586
2012 Winter GE, Rix U, Carlson SM, Gleixner KV, Grebien F, Gridling M, Müller AC, Breitwieser FP, Bilban M, Colinge J, Valent P, Bennett KL, White FM, Superti-Furga G. Systems-pharmacology dissection of a drug synergy in imatinib-resistant CML. Nature Chemical Biology. 8: 905-12. PMID 23023260 DOI: 10.1038/Nchembio.1085  0.352
2012 Johnson H, Del Rosario AM, Bryson BD, Schroeder MA, Sarkaria JN, White FM. Molecular characterization of EGFR and EGFRvIII signaling networks in human glioblastoma tumor xenografts. Molecular & Cellular Proteomics : McP. 11: 1724-40. PMID 22964225 DOI: 10.1074/Mcp.M112.019984  0.711
2012 Naegle KM, White FM, Lauffenburger DA, Yaffe MB. Robust co-regulation of tyrosine phosphorylation sites on proteins reveals novel protein interactions. Molecular Biosystems. 8: 2771-82. PMID 22851037 DOI: 10.1039/C2Mb25200G  0.408
2012 Bryson BD, White FM. Signaling for death: tyrosine phosphorylation in the response to glucose deprivation. Molecular Systems Biology. 8: 591. PMID 22735337 DOI: 10.1038/Msb.2012.27  0.367
2012 Johnson H, White FM. Toward quantitative phosphotyrosine profiling in vivo. Seminars in Cell & Developmental Biology. 23: 854-62. PMID 22677333 DOI: 10.1016/J.Semcdb.2012.05.008  0.603
2012 Carlson SM, White FM. Labeling and identification of direct kinase substrates. Science Signaling. 5: pl3. PMID 22669844 DOI: 10.1126/Scisignal.2002568  0.4
2012 Jun HJ, Johnson H, Bronson RT, de Feraudy S, White F, Charest A. The oncogenic lung cancer fusion kinase CD74-ROS activates a novel invasiveness pathway through E-Syt1 phosphorylation. Cancer Research. 72: 3764-74. PMID 22659450 DOI: 10.1158/0008-5472.Can-11-3990  0.543
2012 Carlson SM, White FM. Expanding applications of chemical genetics in signal transduction. Cell Cycle (Georgetown, Tex.). 11: 1903-9. PMID 22544320 DOI: 10.4161/Cc.19956  0.362
2012 Hackel BJ, Neil JR, White FM, Wittrup KD. Epidermal growth factor receptor downregulation by small heterodimeric binding proteins. Protein Engineering, Design & Selection : Peds. 25: 47-57. PMID 22160867 DOI: 10.1093/Protein/Gzr056  0.336
2012 Jun HJ, Acquaviva J, Chi D, Lessard J, Zhu H, Woolfenden S, Bronson RT, Pfannl R, White F, Housman DE, Iyer L, Whittaker CA, Boskovitz A, Raval A, Charest A. Acquired MET expression confers resistance to EGFR inhibition in a mouse model of glioblastoma multiforme. Oncogene. 31: 3039-50. PMID 22020333 DOI: 10.1038/Onc.2011.474  0.364
2011 Carlson SM, Chouinard CR, Labadorf A, Lam CJ, Schmelzle K, Fraenkel E, White FM. Large-scale discovery of ERK2 substrates identifies ERK-mediated transcriptional regulation by ETV3. Science Signaling. 4: rs11. PMID 22028470 DOI: 10.1126/Scisignal.2002010  0.391
2011 Naegle KM, Welsch RE, Yaffe MB, White FM, Lauffenburger DA. MCAM: multiple clustering analysis methodology for deriving hypotheses and insights from high-throughput proteomic datasets. Plos Computational Biology. 7: e1002119. PMID 21799663 DOI: 10.1371/Journal.Pcbi.1002119  0.378
2011 White FM. The potential cost of high-throughput proteomics. Science Signaling. 4: pe8. PMID 21325204 DOI: 10.1126/Scisignal.2001813  0.315
2011 Liu H, Ong SE, Badu-Nkansah K, Schindler J, White FM, Hynes RO. CUB-domain-containing protein 1 (CDCP1) activates Src to promote melanoma metastasis. Proceedings of the National Academy of Sciences of the United States of America. 108: 1379-84. PMID 21220330 DOI: 10.1073/Pnas.1017228108  0.369
2011 Carlson SM, White FM. Using small molecules and chemical genetics to interrogate signaling networks. Acs Chemical Biology. 6: 75-85. PMID 21077690 DOI: 10.1021/Cb1002834  0.383
2010 Lahesmaa-Korpinen AM, Carlson SM, White FM, Hautaniemi S. Integrated data management and validation platform for phosphorylated tandem mass spectrometry data. Proteomics. 10: 3515-24. PMID 20827731 DOI: 10.1002/Pmic.200900727  0.314
2010 Pines G, Huang PH, Zwang Y, White FM, Yarden Y. EGFRvIV: a previously uncharacterized oncogenic mutant reveals a kinase autoinhibitory mechanism. Oncogene. 29: 5850-60. PMID 20676128 DOI: 10.1038/Onc.2010.313  0.401
2010 Naegle KM, Gymrek M, Joughin BA, Wagner JP, Welsch RE, Yaffe MB, Lauffenburger DA, White FM. PTMScout, a Web resource for analysis of high throughput post-translational proteomics studies. Molecular & Cellular Proteomics : McP. 9: 2558-70. PMID 20631208 DOI: 10.1074/Mcp.M110.001206  0.352
2010 Spangler JB, Neil JR, Abramovitch S, Yarden Y, White FM, Lauffenburger DA, Wittrup KD. Combination antibody treatment down-regulates epidermal growth factor receptor by inhibiting endosomal recycling. Proceedings of the National Academy of Sciences of the United States of America. 107: 13252-7. PMID 20616078 DOI: 10.1073/Pnas.0913476107  0.337
2010 Huang PH, Miraldi ER, Xu AM, Kundukulam VA, Del Rosario AM, Flynn RA, Cavenee WK, Furnari FB, White FM. Phosphotyrosine signaling analysis of site-specific mutations on EGFRvIII identifies determinants governing glioblastoma cell growth. Molecular Biosystems. 6: 1227-37. PMID 20461251 DOI: 10.1039/C001196G  0.67
2010 Iwai LK, Benoist C, Mathis D, White FM. Quantitative phosphoproteomic analysis of T cell receptor signaling in diabetes prone and resistant mice. Journal of Proteome Research. 9: 3135-45. PMID 20438120 DOI: 10.1021/Pr100035B  0.325
2010 Del Rosario AM, White FM. Quantifying oncogenic phosphotyrosine signaling networks through systems biology. Current Opinion in Genetics & Development. 20: 23-30. PMID 20074929 DOI: 10.1016/J.Gde.2009.12.005  0.672
2009 Huang PH, Xu AM, White FM. Oncogenic EGFR signaling networks in glioma. Science Signaling. 2: re6. PMID 19738203 DOI: 10.1126/Scisignal.287Re6  0.367
2009 Morel C, Carlson SM, White FM, Davis RJ. Mcl-1 integrates the opposing actions of signaling pathways that mediate survival and apoptosis. Molecular and Cellular Biology. 29: 3845-52. PMID 19433446 DOI: 10.1128/Mcb.00279-09  0.383
2009 Nichols AM, White FM. Manual validation of peptide sequence and sites of tyrosine phosphorylation from MS/MS spectra. Methods in Molecular Biology (Clifton, N.J.). 492: 143-60. PMID 19241031 DOI: 10.1007/978-1-59745-493-3_8  0.358
2009 Joughin BA, Naegle KM, Huang PH, Yaffe MB, Lauffenburger DA, White FM. An integrated comparative phosphoproteomic and bioinformatic approach reveals a novel class of MPM-2 motifs upregulated in EGFRvIII-expressing glioblastoma cells. Molecular Biosystems. 5: 59-67. PMID 19081932 DOI: 10.1039/B815075C  0.401
2008 Huang PH, White FM. Phosphoproteomics: unraveling the signaling web. Molecular Cell. 31: 777-81. PMID 18922462 DOI: 10.1016/J.Molcel.2008.09.001  0.348
2008 Nita-Lazar A, Saito-Benz H, White FM. Quantitative phosphoproteomics by mass spectrometry: past, present, and future. Proteomics. 8: 4433-43. PMID 18846511 DOI: 10.1002/Pmic.200800231  0.43
2008 Tedford NC, White FM, Radding JA. Illuminating signaling network functional biology through quantitative phosphoproteomic mass spectrometry. Briefings in Functional Genomics & Proteomics. 7: 383-94. PMID 18836207 DOI: 10.1093/Bfgp/Eln037  0.421
2008 White FM. Quantitative phosphoproteomic analysis of signaling network dynamics. Current Opinion in Biotechnology. 19: 404-9. PMID 18619541 DOI: 10.1016/J.Copbio.2008.06.006  0.415
2008 Apgar JF, Toettcher JE, Endy D, White FM, Tidor B. Stimulus design for model selection and validation in cell signaling. Plos Computational Biology. 4: e30. PMID 18282085 DOI: 10.1371/Journal.Pcbi.0040030  0.325
2007 Huang PH, Cavenee WK, Furnari FB, White FM. Uncovering therapeutic targets for glioblastoma: a systems biology approach. Cell Cycle (Georgetown, Tex.). 6: 2750-4. PMID 17986864 DOI: 10.4161/Cc.6.22.4922  0.413
2007 White FM. On the iTRAQ of kinase inhibitors. Nature Biotechnology. 25: 994-6. PMID 17846628 DOI: 10.1038/Nbt0907-994  0.361
2007 Huang PH, Mukasa A, Bonavia R, Flynn RA, Brewer ZE, Cavenee WK, Furnari FB, White FM. Quantitative analysis of EGFRvIII cellular signaling networks reveals a combinatorial therapeutic strategy for glioblastoma. Proceedings of the National Academy of Sciences of the United States of America. 104: 12867-72. PMID 17646646 DOI: 10.1073/Pnas.0705158104  0.424
2007 Zhang Y, Wolf-Yadlin A, White FM. Quantitative proteomic analysis of phosphotyrosine-mediated cellular signaling networks. Methods in Molecular Biology (Clifton, N.J.). 359: 203-12. PMID 17484120 DOI: 10.1007/978-1-59745-255-7_14  0.447
2007 Wolf-Yadlin A, Hautaniemi S, Lauffenburger DA, White FM. Multiple reaction monitoring for robust quantitative proteomic analysis of cellular signaling networks. Proceedings of the National Academy of Sciences of the United States of America. 104: 5860-5. PMID 17389395 DOI: 10.1073/Pnas.0608638104  0.417
2007 Wilker EW, van Vugt MA, Artim SA, Huang PH, Petersen CP, Reinhardt HC, Feng Y, Sharp PA, Sonenberg N, White FM, Yaffe MB. 14-3-3sigma controls mitotic translation to facilitate cytokinesis. Nature. 446: 329-32. PMID 17361185 DOI: 10.1038/Nature05584  0.377
2007 Yaffe MB, White FM. Signaling netwErks get the global treatment. Genome Biology. 8: 202. PMID 17274840 DOI: 10.1186/Gb-2007-8-1-202  0.38
2007 Kumar N, Wolf-Yadlin A, White FM, Lauffenburger DA. Modeling HER2 effects on cell behavior from mass spectrometry phosphotyrosine data. Plos Computational Biology. 3: e4. PMID 17206861 DOI: 10.1371/Journal.Pcbi.0030004  0.443
2006 Tannenbaum SR, White FM. Regulation and specificity of S-nitrosylation and denitrosylation. Acs Chemical Biology. 1: 615-8. PMID 17168564 DOI: 10.1021/Cb600439H  0.32
2006 Wolf-Yadlin A, Kumar N, Zhang Y, Hautaniemi S, Zaman M, Kim HD, Grantcharova V, Lauffenburger DA, White FM. Effects of HER2 overexpression on cell signaling networks governing proliferation and migration. Molecular Systems Biology. 2: 54. PMID 17016520 DOI: 10.1038/Msb4100094  0.421
2006 Schmelzle K, Kane S, Gridley S, Lienhard GE, White FM. Temporal dynamics of tyrosine phosphorylation in insulin signaling. Diabetes. 55: 2171-9. PMID 16873679 DOI: 10.2337/Db06-0148  0.311
2006 Schmelzle K, White FM. Phosphoproteomic approaches to elucidate cellular signaling networks. Current Opinion in Biotechnology. 17: 406-14. PMID 16806894 DOI: 10.1016/J.Copbio.2006.06.004  0.46
2006 Kim JE, White FM. Quantitative analysis of phosphotyrosine signaling networks triggered by CD3 and CD28 costimulation in Jurkat cells. Journal of Immunology (Baltimore, Md. : 1950). 176: 2833-43. PMID 16493040 DOI: 10.4049/Jimmunol.176.5.2833  0.328
2006 Moser K, White FM. Phosphoproteomic analysis of rat liver by high capacity IMAC and LC-MS/MS. Journal of Proteome Research. 5: 98-104. PMID 16396499 DOI: 10.1021/Pr0503073  0.389
2005 Behr JR, Matsumoto Y, White FM, Sasisekharan R. Quantification of isomers from a mixture of twelve heparin and heparan sulfate disaccharides using tandem mass spectrometry. Rapid Communications in Mass Spectrometry : Rcm. 19: 2553-62. PMID 16124039 DOI: 10.1002/Rcm.2079  0.315
2005 Kim JE, Tannenbaum SR, White FM. Global phosphoproteome of HT-29 human colon adenocarcinoma cells. Journal of Proteome Research. 4: 1339-46. PMID 16083285 DOI: 10.1021/Pr050048H  0.42
2005 Zhang Y, Wolf-Yadlin A, Ross PL, Pappin DJ, Rush J, Lauffenburger DA, White FM. Time-resolved mass spectrometry of tyrosine phosphorylation sites in the epidermal growth factor receptor signaling network reveals dynamic modules. Molecular & Cellular Proteomics : McP. 4: 1240-50. PMID 15951569 DOI: 10.1074/Mcp.M500089-Mcp200  0.462
2004 Chen WG, White FM. Proteomic analysis of cellular signaling. Expert Review of Proteomics. 1: 343-54. PMID 15966830 DOI: 10.1586/14789450.1.3.343  0.407
2003 Saibil SD, Ohteki T, White FM, Luscher M, Zakarian A, Elford A, Shabanowitz J, Nishina H, Hugo P, Penninger J, Barber B, Hunt DF, Ohashi PS. Weak agonist self-peptides promote selection and tuning of virus-specific T cells. European Journal of Immunology. 33: 685-96. PMID 12616489 DOI: 10.1002/Eji.200323143  0.301
2003 Ficarro S, Chertihin O, Westbrook VA, White F, Jayes F, Kalab P, Marto JA, Shabanowitz J, Herr JC, Hunt DF, Visconti PE. Phosphoproteome analysis of capacitated human sperm. Evidence of tyrosine phosphorylation of a kinase-anchoring protein 3 and valosin-containing protein/p97 during capacitation. The Journal of Biological Chemistry. 278: 11579-89. PMID 12509440 DOI: 10.1074/Jbc.M202325200  0.388
2002 Gioeli D, Ficarro SB, Kwiek JJ, Aaronson D, Hancock M, Catling AD, White FM, Christian RE, Settlage RE, Shabanowitz J, Hunt DF, Weber MJ. Androgen receptor phosphorylation. Regulation and identification of the phosphorylation sites. The Journal of Biological Chemistry. 277: 29304-14. PMID 12015328 DOI: 10.1074/Jbc.M204131200  0.385
2002 Ficarro SB, McCleland ML, Stukenberg PT, Burke DJ, Ross MM, Shabanowitz J, Hunt DF, White FM. Phosphoproteome analysis by mass spectrometry and its application to Saccharomyces cerevisiae. Nature Biotechnology. 20: 301-5. PMID 11875433 DOI: 10.1038/Nbt0302-301  0.42
2001 Luckey CJ, Marto JA, Partridge M, Hall E, White FM, Lippolis JD, Shabanowitz J, Hunt DF, Engelhard VH. Differences in the expression of human class I MHC alleles and their associated peptides in the presence of proteasome inhibitors. Journal of Immunology (Baltimore, Md. : 1950). 167: 1212-21. PMID 11466336 DOI: 10.4049/Jimmunol.167.3.1212  0.303
2000 Zarling AL, Ficarro SB, White FM, Shabanowitz J, Hunt DF, Engelhard VH. Phosphorylated peptides are naturally processed and presented by major histocompatibility complex class I molecules in vivo. The Journal of Experimental Medicine. 192: 1755-62. PMID 11120772 DOI: 10.1084/Jem.192.12.1755  0.313
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