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Gorakhnath R. Jachak - Publications

Affiliations: 
2013- CSIR-National Chemical Laboratory, Pune, India 
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16 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Jachak GR, Kashinath K, Vasudevan N, Athawale PR, Choudhury R, Dange SS, Agarwal H, Barthwal MK, Reddy DS. Comprehensive Study on Solomonamides: Total Synthesis, Stereochemical Revision, and SAR Studies toward Identification of Simplified Lead. The Journal of Organic Chemistry. 88: 17088-17133. PMID 38051995 DOI: 10.1021/acs.joc.3c01987  0.715
2023 Jachak GR, Orimoloye MO, Aldrich CC. Gram Scale Synthesis of Membrane-Active Antibacterial 4-Quinolone Lead Compound. The Journal of Organic Chemistry. 88: 6209-6217. PMID 37071556 DOI: 10.1021/acs.joc.3c00239  0.344
2021 Jachak GR, Tharra PR, Sevelda P, Švenda J. Stereocontrolled Synthesis of Pseurotin A. The Journal of Organic Chemistry. PMID 34378926 DOI: 10.1021/acs.joc.1c01152  0.384
2019 Reddy DS, Jachak G, Athawale P, Choudhury R, Kashinath K. Access to Stereoisomer Library of Solomonamide Macrocycles. Chemistry, An Asian Journal. PMID 31512378 DOI: 10.1002/Asia.201901075  0.68
2018 Jachak GR, Athawale PR, Agarwal H, Barthwal MK, Lauro G, Bifulco G, Reddy DS. Total synthesis of the potent anti-inflammatory natural product solomonamide A along with structural revision and biological activity evaluation. Organic & Biomolecular Chemistry. PMID 30478463 DOI: 10.1039/C8Ob02713G  0.771
2018 Athawale PR, Jachak GR, Shukla A, Shanmugam D, Reddy DS. Efforts To Access the Potent Antitrypanosomal Marine Natural Product Janadolide: Synthesis of Des--butyl Janadolide and Its Biological Evaluation. Acs Omega. 3: 2383-2389. PMID 30023831 DOI: 10.1021/acsomega.7b01920  0.771
2018 Verma AK, Waghmare TS, Jachak GR, Philkhana SC, Reddy DS, Basu A. Nitrosporeusine analogue ameliorates Chandipura virus induced inflammatory response in CNS via NFκb inactivation in microglia. Plos Neglected Tropical Diseases. 12: e0006648. PMID 30001342 DOI: 10.1371/Journal.Pntd.0006648  0.443
2018 Das P, Babbar P, Malhotra N, Sharma M, Jachak GR, Gonnade RG, Shanmugam D, Harlos K, Yogavel M, Sharma A, Reddy DS. Specific Stereoisomeric Conformations Determine the Drug Potency of Cladosporin Scaffold against Malarial Parasite. Journal of Medicinal Chemistry. PMID 29779382 DOI: 10.1021/Acs.Jmedchem.8B00565  0.672
2018 Jachak GR, Reddy DS. Scalable Synthesis of Both Enantiomers of Vigabatrin, an Antiepileptic Drug European Journal of Organic Chemistry. 2019: 1257-1260. DOI: 10.1002/Ejoc.201801617  0.512
2017 Thakare R, Singh AK, Das S, Vasudevan N, Jachak GR, Reddy DS, Dasgupta A, Chopra S. Repurposing ivacaftor for treatment of staphylococcus aureus infections. International Journal of Antimicrobial Agents. PMID 28694231 DOI: 10.1016/J.Ijantimicag.2017.03.020  0.449
2017 Philkhana SC, Verma AK, Jachak GR, Hazra B, Basu A, Reddy DS. Identification of new anti-inflammatory agents based on nitrosporeusine natural products of marine origin. European Journal of Medicinal Chemistry. 135: 89-109. PMID 28433779 DOI: 10.1016/J.Ejmech.2017.04.015  0.567
2016 Kashinath K, Jachak GR, Athawale PR, Marelli UK, Gonnade RG, Reddy DS. Total Synthesis of the Marine Natural Product Solomonamide B Necessitates Stereochemical Revision. Organic Letters. PMID 27332700 DOI: 10.1021/Acs.Orglett.6B01395  0.767
2015 Jachak GR, Ramesh R, Sant DG, Jorwekar SU, Jadhav MR, Tupe SG, Deshpande MV, Reddy DS. Silicon Incorporated Morpholine Antifungals: Design, Synthesis, and Biological Evaluation. Acs Medicinal Chemistry Letters. 6: 1111-1116. PMID 26617963 DOI: 10.1021/Acsmedchemlett.5B00245  0.565
2015 Philkhana SC, Jachak GR, Gunjal VB, Dhage NM, Bansode AH, Reddy DS. First synthesis of nitrosporeusines, alkaloids with multiple biological activities Tetrahedron Letters. 56: 1252-1254. DOI: 10.1016/J.Tetlet.2015.01.143  0.718
2015 Vasudevan N, Jachak GR, Reddy DS. Breaking and Making of Rings: A Method for the Preparation of 4-Quinolone-3-carboxylic Acid Amides and the Expensive Drug Ivacaftor European Journal of Organic Chemistry. 2015: 7433-7437. DOI: 10.1002/Ejoc.201501048  0.519
2014 Swaroop PS, Tripathy S, Jachak G, Reddy DS. Efforts towards the synthesis of microsporin B: Ready access to both the enantiomers of the key amino acid fragment Tetrahedron Letters. 4777-4779. DOI: 10.1016/J.Tetlet.2014.06.093  0.532
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