Huaxi Xu, Ph.D. - Publications

Affiliations: 
2003- SBP Medical Discovery Institute 

36 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Tu S, Akhtar MW, Escorihuela RM, Amador-Arjona A, Swarup V, Parker J, Zaremba JD, Holland T, Bansal N, Holohan DR, Lopez K, Ryan SD, Chan SF, Yan L, Zhang X, ... ... Xu H, et al. NitroSynapsin therapy for a mouse MEF2C haploinsufficiency model of human autism. Nature Communications. 8: 1488. PMID 29133852 DOI: 10.1038/s41467-017-01563-8  0.48
2016 Huang TY, Zhao Y, Li X, Wang X, Tseng IC, Thompson R, Tu S, Willnow TE, Zhang YW, Xu H. SNX27 and SORLA Interact to Reduce Amyloidogenic Subcellular Distribution and Processing of Amyloid Precursor Protein. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 7996-8011. PMID 27466343 DOI: 10.1523/JNEUROSCI.0206-16.2016  0.56
2016 Wang C, Niu M, Zhou Z, Zheng X, Zhang L, Tian Y, Yu X, Bu G, Xu H, Ma Q, Zhang YW. VPS35 regulates cell surface recycling and signaling of dopamine receptor D1. Neurobiology of Aging. 46: 22-31. PMID 27460146 DOI: 10.1016/j.neurobiolaging.2016.05.016  0.56
2016 Zheng Q, Zheng X, Zhang L, Luo H, Qian L, Fu X, Liu Y, Gao Y, Niu M, Meng J, Zhang M, Bu G, Xu H, Zhang YW. The Neuron-Specific Protein TMEM59L Mediates Oxidative Stress-Induced Cell Death. Molecular Neurobiology. PMID 27324899 DOI: 10.1007/s12035-016-9997-9  0.56
2016 Bie Q, Sun C, Gong A, Li C, Su Z, Zheng D, Ji X, Wu Y, Guo Q, Wang S, Xu H. Non-tumor tissue derived interleukin-17B activates IL-17RB/AKT/β-catenin pathway to enhance the stemness of gastric cancer. Scientific Reports. 6: 25447. PMID 27146881 DOI: 10.1038/srep25447  0.56
2016 Zhang X, Hu J, Zhong L, Wang N, Yang L, Liu CC, Li H, Wang X, Zhou Y, Zhang Y, Xu H, Bu G, Zhuang J. Quercetin stabilizes apolipoprotein E and reduces brain Aβ levels in amyloid model mice. Neuropharmacology. PMID 27114256 DOI: 10.1016/j.neuropharm.2016.04.032  0.56
2016 Ying X, Su Z, Bie Q, Zhang P, Yang H, Wu Y, Xu Y, Wu J, Zhang M, Wang S, Xu H. Synergistically increased ILC2 and Th9 cells in lung tissue jointly promote the pathological process of asthma in mice. Molecular Medicine Reports. PMID 27109139 DOI: 10.3892/mmr.2016.5174  0.56
2016 Ma J, Feng D, Wei Y, Tian J, Tang X, Rui K, Lu L, Xu H, Wang S. Blockade of Glucocorticoid-Induced Tumor Necrosis Factor-Receptor-Related Protein Signaling Ameliorates Murine Collagen-Induced Arthritis by Modulating Follicular Helper T Cells. The American Journal of Pathology. PMID 27106763 DOI: 10.1016/j.ajpath.2016.02.010  0.56
2016 Su Z, Zhang P, Yu Y, Lu H, Liu Y, Ni P, Su X, Wang D, Liu Y, Wang J, Shen H, Xu W, Xu H. HMGB1 Facilitated Macrophage Reprogramming towards a Proinflammatory M1-like Phenotype in Experimental Autoimmune Myocarditis Development. Scientific Reports. 6: 21884. PMID 26899795 DOI: 10.1038/srep21884  0.56
2016 Barini E, Antico O, Zhao Y, Asta F, Tucci V, Catelani T, Marotta R, Xu H, Gasparini L. Metformin promotes tau aggregation and exacerbates abnormal behavior in a mouse model of tauopathy. Molecular Neurodegeneration. 11: 16. PMID 26858121 DOI: 10.1186/s13024-016-0082-7  0.56
2016 Mao L, Wu J, Shen L, Yang J, Chen J, Xu H. Enterovirus 71 transmission by exosomes establishes a productive infection in human neuroblastoma cells. Virus Genes. PMID 26837894 DOI: 10.1007/s11262-016-1292-3  0.56
2016 Yan L, Chen Y, Li W, Huang X, Badie H, Jian F, Huang T, Zhao Y, Cohen SN, Li L, Zhang YW, Luo H, Tu S, Xu H. RPS23RG1 reduces Aβ oligomer-induced synaptic and cognitive deficits. Scientific Reports. 6: 18668. PMID 26733416 DOI: 10.1038/srep18668  0.56
2015 Chen X, Su Z, Wang S, Xu H. Clinical and prognostic significance of Arl4c expression in colorectal cancer. Cancer Biomarkers : Section a of Disease Markers. PMID 26756615 DOI: 10.3233/CBM-150562  0.56
2015 Peng H, Liu Y, Tian J, Ma J, Tang X, Rui K, Tian X, Mao C, Lu L, Xu H, Jiang P, Wang S. The Long Noncoding RNA IFNG-AS1 Promotes T Helper Type 1 Cells Response in Patients with Hashimoto's Thyroiditis. Scientific Reports. 5: 17702. PMID 26634912 DOI: 10.1038/srep17702  0.56
2015 Yang H, Huang L, Barnie PA, Su Z, Mi Z, Chen J, Aparna V, Kumar D, Xu H. Characterization and distribution of drug resistance associated β-lactamase, membrane porin and efflux pump genes in MDR A. baumannii isolated from Zhenjiang, China. International Journal of Clinical and Experimental Medicine. 8: 15393-15402. PMID 26629028  0.56
2015 Chen XF, Wei Z, Wang T, Zhang ZL, Wang Y, Heckman MG, Diehl NN, Zhang YW, Xu H, Bu G. Demographic and Lifestyle Characteristics, but Not Apolipoprotein E Genotype, Are Associated with Intelligence among Young Chinese College Students. Plos One. 10: e0143157. PMID 26574747 DOI: 10.1371/journal.pone.0143157  0.56
2015 Chen X, Dong C, Law PT, Chan MT, Su Z, Wang S, Wu WK, Xu H. MicroRNA-145 targets TRIM2 and exerts tumor-suppressing functions in epithelial ovarian cancer. Gynecologic Oncology. PMID 26472353 DOI: 10.1016/j.ygyno.2015.10.008  0.56
2015 Rui K, Zhang Z, Tian J, Lin X, Wang X, Ma J, Tang X, Xu H, Lu L, Wang S. Olfactory ecto-mesenchymal stem cells possess immunoregulatory function and suppress autoimmune arthritis. Cellular & Molecular Immunology. PMID 26388237 DOI: 10.1038/cmi.2015.82  0.56
2015 Atagi Y, Liu CC, Painter MM, Chen XF, Verbeeck C, Zheng H, Li X, Rademakers R, Kang SS, Xu H, Younkin S, Das P, Fryer JD, Bu G. Apolipoprotein E is a Ligand for Triggering Receptor Expressed on Myeloid Cells 2 (TREM2). The Journal of Biological Chemistry. PMID 26374899 DOI: 10.1074/jbc.M115.679043  0.56
2015 Painter MM, Atagi Y, Liu CC, Rademakers R, Xu H, Fryer JD, Bu G. TREM2 in CNS homeostasis and neurodegenerative disease. Molecular Neurodegeneration. 10: 43. PMID 26337043 DOI: 10.1186/s13024-015-0040-9  0.56
2015 Zhao Y, Tseng IC, Heyser CJ, Rockenstein E, Mante M, Adame A, Zheng Q, Huang T, Wang X, Arslan PE, Chakrabarty P, Wu C, Bu G, Mobley WC, Zhang YW, ... ... Xu H, et al. Appoptosin-Mediated Caspase Cleavage of Tau Contributes to Progressive Supranuclear Palsy Pathogenesis. Neuron. 87: 963-75. PMID 26335643 DOI: 10.1016/j.neuron.2015.08.020  0.56
2015 Wu Y, Yan Y, Su Z, Bie Q, Wu J, Wang S, Yu Y, Ding H, Lu P, Xu H. Enhanced circulating ILC2s accompany by upregulated MDSCs in patients with asthma. International Journal of Clinical and Experimental Pathology. 8: 3568-79. PMID 26097539  0.56
2015 Zhong L, Chen XF, Zhang ZL, Wang Z, Shi XZ, Xu K, Zhang YW, Xu H, Bu G. DAP12 Stabilizes the C-terminal Fragment of the Triggering Receptor Expressed on Myeloid Cells-2 (TREM2) and Protects against LPS-induced Pro-inflammatory Response. The Journal of Biological Chemistry. 290: 15866-77. PMID 25957402 DOI: 10.1074/jbc.M115.645986  0.56
2015 Peng H, Liu Y, Tian J, Ma J, Tang X, Yang J, Rui K, Zhang Y, Mao C, Lu L, Xu H, Wang S. Decreased expression of microRNA-125a-3p upregulates interleukin-23 receptor in patients with Hashimoto's thyroiditis. Immunologic Research. 62: 129-36. PMID 25863684 DOI: 10.1007/s12026-015-8643-3  0.56
2014 Wang X, Huang T, Zhao Y, Zheng Q, Thompson RC, Bu G, Zhang YW, Hong W, Xu H. Sorting nexin 27 regulates Aβ production through modulating γ-secretase activity. Cell Reports. 9: 1023-33. PMID 25437557 DOI: 10.1016/j.celrep.2014.09.037  0.56
2014 Tu S, Okamoto S, Lipton SA, Xu H. Oligomeric Aβ-induced synaptic dysfunction in Alzheimer's disease. Molecular Neurodegeneration. 9: 48. PMID 25394486 DOI: 10.1186/1750-1326-9-48  0.56
2009 Zhang YW, Liu S, Zhang X, Li WB, Chen Y, Huang X, Sun L, Luo W, Netzer WJ, Threadgill R, Wiegand G, Wang R, Cohen SN, Greengard P, Liao FF, ... ... Xu H, et al. A functional mouse retroposed gene Rps23r1 reduces Alzheimer's beta-amyloid levels and tau phosphorylation. Neuron. 64: 328-40. PMID 19914182 DOI: 10.1016/j.neuron.2009.08.036  0.56
2006 Cai D, Netzer WJ, Zhong M, Lin Y, Du G, Frohman M, Foster DA, Sisodia SS, Xu H, Gorelick FS, Greengard P. Presenilin-1 uses phospholipase D1 as a negative regulator of beta-amyloid formation. Proceedings of the National Academy of Sciences of the United States of America. 103: 1941-6. PMID 16449386 DOI: 10.1073/pnas.0510708103  0.56
2006 Cai D, Zhong M, Wang R, Netzer WJ, Shields D, Zheng H, Sisodia SS, Foster DA, Gorelick FS, Xu H, Greengard P. Phospholipase D1 corrects impaired betaAPP trafficking and neurite outgrowth in familial Alzheimer's disease-linked presenilin-1 mutant neurons. Proceedings of the National Academy of Sciences of the United States of America. 103: 1936-40. PMID 16449385 DOI: 10.1073/pnas.0510710103  0.56
2004 Wang H, Luo WJ, Zhang YW, Li YM, Thinakaran G, Greengard P, Xu H. Presenilins and gamma-secretase inhibitors affect intracellular trafficking and cell surface localization of the gamma-secretase complex components. The Journal of Biological Chemistry. 279: 40560-6. PMID 15247291 DOI: 10.1074/jbc.M404345200  0.56
2003 Netzer WJ, Dou F, Cai D, Veach D, Jean S, Li Y, Bornmann WG, Clarkson B, Xu H, Greengard P. Gleevec inhibits beta-amyloid production but not Notch cleavage. Proceedings of the National Academy of Sciences of the United States of America. 100: 12444-9. PMID 14523244 DOI: 10.1073/pnas.1534745100  0.56
2003 Dou F, Netzer WJ, Tanemura K, Li F, Hartl FU, Takashima A, Gouras GK, Greengard P, Xu H. Chaperones increase association of tau protein with microtubules. Proceedings of the National Academy of Sciences of the United States of America. 100: 721-6. PMID 12522269 DOI: 10.1073/pnas.242720499  0.56
2003 Cai D, Leem JY, Greenfield JP, Wang P, Kim BS, Wang R, Lopes KO, Kim SH, Zheng H, Greengard P, Sisodia SS, Thinakaran G, Xu H. Presenilin-1 regulates intracellular trafficking and cell surface delivery of beta-amyloid precursor protein. The Journal of Biological Chemistry. 278: 3446-54. PMID 12435726 DOI: 10.1074/jbc.M209065200  0.56
2002 Takahashi RH, Milner TA, Li F, Nam EE, Edgar MA, Yamaguchi H, Beal MF, Xu H, Greengard P, Gouras GK. Intraneuronal Alzheimer abeta42 accumulates in multivesicular bodies and is associated with synaptic pathology. The American Journal of Pathology. 161: 1869-79. PMID 12414533  0.56
2002 Gasparini L, Netzer WJ, Greengard P, Xu H. Does insulin dysfunction play a role in Alzheimer's disease? Trends in Pharmacological Sciences. 23: 288-93. PMID 12084635 DOI: 10.1016/S0165-6147(02)02037-0  0.56
2002 Greenfield JP, Leung LW, Cai D, Kaasik K, Gross RS, Rodriguez-Boulan E, Greengard P, Xu H. Estrogen lowers Alzheimer beta-amyloid generation by stimulating trans-Golgi network vesicle biogenesis. The Journal of Biological Chemistry. 277: 12128-36. PMID 11823458 DOI: 10.1074/jbc.M110009200  0.56
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