Alfredo Kirkwood - Publications

Affiliations: 
Johns Hopkins University, Baltimore, MD 
Area:
Plasticity

74 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Tran T, Unal CT, Severin D, Zaborszky L, Rotstein HG, Kirkwood A, Golowasch J. Ionic current correlations are ubiquitous across phyla. Scientific Reports. 9: 1687. PMID 30737430 DOI: 10.1038/s41598-018-38405-6  0.52
2018 Fernandez DC, Fogerson PM, Lazzerini Ospri L, Thomsen MB, Layne RM, Severin D, Zhan J, Singer JH, Kirkwood A, Zhao H, Berson DM, Hattar S. Light Affects Mood and Learning through Distinct Retina-Brain Pathways. Cell. PMID 30173913 DOI: 10.1016/j.cell.2018.08.004  0.4
2018 Tran T, Gallagher M, Kirkwood A. Enhanced postsynaptic inhibitory strength in hippocampal principal cells in high-performing aged rats. Neurobiology of Aging. 70: 92-101. PMID 30007169 DOI: 10.1016/j.neurobiolaging.2018.06.008  0.68
2017 Chen Y, Granger AJ, Tran T, Saulnier JL, Kirkwood A, Sabatini BL. Endogenous Gαq-Coupled Neuromodulator Receptors Activate Protein Kinase A. Neuron. PMID 29154125 DOI: 10.1016/j.neuron.2017.10.023  0.52
2017 Li S, Wang L, Tie X, Sohya K, Lin X, Kirkwood A, Jiang B. Brief novel visual experience fundamentally changes synaptic plasticity in the mouse visual cortex. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 28821676 DOI: 10.1523/JNEUROSCI.0334-17.2017  0.52
2017 Gao M, Whitt JL, Huang S, Lee A, Mihalas S, Kirkwood A, Lee HK. Experience-dependent homeostasis of 'noise' at inhibitory synapses preserves information coding in adult visual cortex. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 372. PMID 28093550 DOI: 10.1098/rstb.2016.0156  1
2016 Gu Y, Tran T, Murase S, Borrell A, Kirkwood A, Quinlan EM. Neuregulin-Dependent Regulation of Fast-Spiking Interneuron Excitability Controls the Timing of the Critical Period. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 10285-10295. PMID 27707966 DOI: 10.1523/JNEUROSCI.4242-15.2016  1
2016 Posada-Duque RA, Ramirez O, Härtel S, Inestrosa NC, Bodaleo F, González-Billault C, Kirkwood A, Cardona-Gómez GP. CDK5 downregulation enhances synaptic plasticity. Cellular and Molecular Life Sciences : Cmls. PMID 27506619 DOI: 10.1007/s00018-016-2333-8  0.52
2016 Wang H, Ardiles AO, Yang S, Tran T, Posada-Duque R, Valdivia G, Baek M, Chuang YA, Palacios AG, Gallagher M, Worley P, Kirkwood A. Metabotropic Glutamate Receptors Induce a Form of LTP Controlled by Translation and Arc Signaling in the Hippocampus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 1723-9. PMID 26843652 DOI: 10.1523/JNEUROSCI.0878-15.2016  1
2015 Huang S, Hokenson K, Bandyopadhyay S, Russek SJ, Kirkwood A. Brief Dark Exposure Reduces Tonic Inhibition in Visual Cortex. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 15916-20. PMID 26631472 DOI: 10.1523/JNEUROSCI.1813-15.2015  1
2015 He K, Huertas M, Hong SZ, Tie X, Hell JW, Shouval H, Kirkwood A. Distinct Eligibility Traces for LTP and LTD in Cortical Synapses. Neuron. 88: 528-38. PMID 26593091 DOI: 10.1016/j.neuron.2015.09.037  1
2015 Megill A, Tran T, Eldred K, Lee NJ, Wong PC, Hoe HS, Kirkwood A, Lee HK. Defective Age-Dependent Metaplasticity in a Mouse Model of Alzheimer's Disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 11346-57. PMID 26269641 DOI: 10.1523/JNEUROSCI.5289-14.2015  1
2015 Kirkwood A. Balancing excitation and inhibition. Neuron. 86: 348-50. PMID 25905806 DOI: 10.1016/j.neuron.2015.04.009  1
2014 Yang S, Yang S, Park JS, Kirkwood A, Bao S. Failed stabilization for long-term potentiation in the auditory cortex of FMR1 knockout mice. Plos One. 9: e104691. PMID 25115962 DOI: 10.1371/journal.pone.0104691  1
2014 Huang S, Rozas C, Treviño M, Contreras J, Yang S, Song L, Yoshioka T, Lee HK, Kirkwood A. Associative Hebbian synaptic plasticity in primate visual cortex. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 7575-9. PMID 24872561 DOI: 10.1523/JNEUROSCI.0983-14.2014  1
2014 Wang H, Megill A, Wong PC, Kirkwood A, Lee HK. Postsynaptic target specific synaptic dysfunctions in the CA3 area of BACE1 knockout mice. Plos One. 9: e92279. PMID 24637500 DOI: 10.1371/journal.pone.0092279  1
2014 Mihalas S, Millman D, Iyer R, Kirkwood A, Niebur E. Nonconservative Neuronal Networks During Up-States Self-Organize Near Critical Points Criticality in Neural Systems. 437-464. DOI: 10.1002/9783527651009.ch21  1
2013 Huang S, Huganir RL, Kirkwood A. Adrenergic gating of Hebbian spike-timing-dependent plasticity in cortical interneurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 13171-8. PMID 23926270 DOI: 10.1523/JNEUROSCI.5741-12.2013  1
2013 Yang S, Megill A, Ardiles AO, Ransom S, Tran T, Koh MT, Lee HK, Gallagher M, Kirkwood A. Integrity of mGluR-LTD in the associative/commissural inputs to CA3 correlates with successful aging in rats. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 12670-8. PMID 23904603 DOI: 10.1523/JNEUROSCI.1086-13.2013  1
2013 Gu Y, Huang S, Chang MC, Worley P, Kirkwood A, Quinlan EM. Obligatory role for the immediate early gene NARP in critical period plasticity. Neuron. 79: 335-46. PMID 23889936 DOI: 10.1016/j.neuron.2013.05.016  1
2013 Megill A, Lee T, DiBattista AM, Song JM, Spitzer MH, Rubinshtein M, Habib LK, Capule CC, Mayer M, Turner RS, Kirkwood A, Yang J, Pak DT, Lee HK, Hoe HS. A tetra(ethylene glycol) derivative of benzothiazole aniline enhances Ras-mediated spinogenesis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 9306-18. PMID 23719799 DOI: 10.1523/JNEUROSCI.1615-12.2013  1
2013 Ardiles AO, Ewer J, Acosta ML, Kirkwood A, Martinez AD, Ebensperger LA, Bozinovic F, Lee TM, Palacios AG. Octodon degus (Molina 1782): a model in comparative biology and biomedicine. Cold Spring Harbor Protocols. 2013: 312-8. PMID 23547147 DOI: 10.1101/pdb.emo071357  1
2012 LeGates TA, Altimus CM, Wang H, Lee HK, Yang S, Zhao H, Kirkwood A, Weber ET, Hattar S. Aberrant light directly impairs mood and learning through melanopsin-expressing neurons. Nature. 491: 594-8. PMID 23151476 DOI: 10.1038/nature11673  1
2012 Guo Y, Huang S, de Pasquale R, McGehrin K, Lee HK, Zhao K, Kirkwood A. Dark exposure extends the integration window for spike-timing-dependent plasticity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 15027-35. PMID 23100424 DOI: 10.1523/JNEUROSCI.2545-12.2012  1
2012 Ardiles AO, Tapia-Rojas CC, Mandal M, Alexandre F, Kirkwood A, Inestrosa NC, Palacios AG. Postsynaptic dysfunction is associated with spatial and object recognition memory loss in a natural model of Alzheimer's disease. Proceedings of the National Academy of Sciences of the United States of America. 109: 13835-40. PMID 22869717 DOI: 10.1073/pnas.1201209109  1
2012 Wang H, Megill A, He K, Kirkwood A, Lee HK. Consequences of inhibiting amyloid precursor protein processing enzymes on synaptic function and plasticity. Neural Plasticity. 2012: 272374. PMID 22792491 DOI: 10.1155/2012/272374  1
2012 Huang S, Treviño M, He K, Ardiles A, Pasquale Rd, Guo Y, Palacios A, Huganir R, Kirkwood A. Pull-push neuromodulation of LTP and LTD enables bidirectional experience-induced synaptic scaling in visual cortex. Neuron. 73: 497-510. PMID 22325202 DOI: 10.1016/j.neuron.2011.11.023  1
2011 Lee HK, Kirkwood A. AMPA receptor regulation during synaptic plasticity in hippocampus and neocortex. Seminars in Cell & Developmental Biology. 22: 514-20. PMID 21856433 DOI: 10.1016/j.semcdb.2011.06.007  1
2011 Kulkarni M, Zhang K, Kirkwood A. Single-cell persistent activity in anterodorsal thalamus. Neuroscience Letters. 498: 179-84. PMID 21362457 DOI: 10.1016/j.neulet.2011.02.051  1
2011 Lorca RA, Rozas C, Loyola S, Moreira-Ramos S, Zeise ML, Kirkwood A, Huidobro-Toro JP, Morales B. Zinc enhances long-term potentiation through P2X receptor modulation in the hippocampal CA1 region. The European Journal of Neuroscience. 33: 1175-85. PMID 21324005 DOI: 10.1111/j.1460-9568.2010.07589.x  1
2011 Muñoz P, Humeres A, Elgueta C, Kirkwood A, Hidalgo C, Núñez MT. Iron mediates N-methyl-D-aspartate receptor-dependent stimulation of calcium-induced pathways and hippocampal synaptic plasticity. The Journal of Biological Chemistry. 286: 13382-92. PMID 21296883 DOI: 10.1074/jbc.M110.213785  1
2010 Millman D, Mihalas S, Kirkwood A, Niebur E. Self-organized criticality occurs in non-conservative neuronal networks during Up states. Nature Physics. 6: 801-805. PMID 21804861 DOI: 10.1038/nphys1757  1
2010 Pawlak V, Wickens JR, Kirkwood A, Kerr JN. Timing is not Everything: Neuromodulation Opens the STDP Gate. Frontiers in Synaptic Neuroscience. 2: 146. PMID 21423532 DOI: 10.3389/fnsyn.2010.00146  1
2010 Huang S, Gu Y, Quinlan EM, Kirkwood A. A refractory period for rejuvenating GABAergic synaptic transmission and ocular dominance plasticity with dark exposure. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 16636-42. PMID 21148002 DOI: 10.1523/JNEUROSCI.4384-10.2010  1
2010 Zhang D, Zhang C, Ho A, Kirkwood A, Südhof TC, Shen J. Inactivation of presenilins causes pre-synaptic impairment prior to post-synaptic dysfunction. Journal of Neurochemistry. 115: 1215-21. PMID 20854432 DOI: 10.1111/j.1471-4159.2010.07011.x  0.4
2010 Jiang B, Huang S, de Pasquale R, Millman D, Song L, Lee HK, Tsumoto T, Kirkwood A. The maturation of GABAergic transmission in visual cortex requires endocannabinoid-mediated LTD of inhibitory inputs during a critical period. Neuron. 66: 248-59. PMID 20435001 DOI: 10.1016/j.neuron.2010.03.021  1
2009 Savonenko A, Munoz P, Melnikova T, Wang Q, Liang X, Breyer RM, Montine TJ, Kirkwood A, Andreasson K. Impaired cognition, sensorimotor gating, and hippocampal long-term depression in mice lacking the prostaglandin E2 EP2 receptor. Experimental Neurology. 217: 63-73. PMID 19416671 DOI: 10.1016/j.expneurol.2009.01.016  1
2008 Boric K, Muñoz P, Gallagher M, Kirkwood A. Potential adaptive function for altered long-term potentiation mechanisms in aging hippocampus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 8034-9. PMID 18685028 DOI: 10.1523/JNEUROSCI.2036-08.2008  1
2007 Seol GH, Ziburkus J, Huang S, Song L, Kim IT, Takamiya K, Huganir RL, Lee HK, Kirkwood A. Neuromodulators control the polarity of spike-timing-dependent synaptic plasticity. Neuron. 55: 919-29. PMID 17880895 DOI: 10.1016/j.neuron.2007.08.013  1
2007 Jiang B, Treviño M, Kirkwood A. Sequential development of long-term potentiation and depression in different layers of the mouse visual cortex. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 9648-52. PMID 17804625 DOI: 10.1523/JNEUROSCI.2655-07.2007  1
2007 Seol GH, Ziburkus J, Huang S, Song L, Kim IT, Takamiya K, Huganir RL, Lee HK, Kirkwood A. Neuromodulators Control the Polarity of Spike-Timing-Dependent Synaptic Plasticity (DOI:10.1016/j.neuron.2007.08.013) Neuron. 56: 754. DOI: 10.1016/j.neuron.2007.11.007  1
2007 Kirkwood A. Neuromodulation of cortical synaptic plasticity Monoaminergic Modulation of Cortical Excitability. 209-216. DOI: 10.1007/978-0-387-72256-6_14  1
2006 Goel A, Jiang B, Xu LW, Song L, Kirkwood A, Lee HK. Cross-modal regulation of synaptic AMPA receptors in primary sensory cortices by visual experience. Nature Neuroscience. 9: 1001-3. PMID 16819524 DOI: 10.1038/nn1725  1
2005 Choi SY, Chang J, Jiang B, Seol GH, Min SS, Han JS, Shin HS, Gallagher M, Kirkwood A. Multiple receptors coupled to phospholipase C gate long-term depression in visual cortex. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 11433-43. PMID 16339037 DOI: 10.1523/JNEUROSCI.4084-05.2005  1
2005 Lee HK, Min SS, Gallagher M, Kirkwood A. NMDA receptor-independent long-term depression correlates with successful aging in rats. Nature Neuroscience. 8: 1657-9. PMID 16286930 DOI: 10.1038/nn1586  1
2005 Saura CA, Chen G, Malkani S, Choi SY, Takahashi RH, Zhang D, Gouras GK, Kirkwood A, Morris RG, Shen J. Conditional inactivation of presenilin 1 prevents amyloid accumulation and temporarily rescues contextual and spatial working memory impairments in amyloid precursor protein transgenic mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 6755-64. PMID 16033885 DOI: 10.1523/JNEUROSCI.1247-05.2005  1
2005 Jiang B, Huang ZJ, Morales B, Kirkwood A. Maturation of GABAergic transmission and the timing of plasticity in visual cortex. Brain Research. Brain Research Reviews. 50: 126-33. PMID 16024085 DOI: 10.1016/j.brainresrev.2005.05.007  1
2004 Hayashi ML, Choi SY, Rao BS, Jung HY, Lee HK, Zhang D, Chattarji S, Kirkwood A, Tonegawa S. Altered cortical synaptic morphology and impaired memory consolidation in forebrain- specific dominant-negative PAK transgenic mice. Neuron. 42: 773-87. PMID 15182717 DOI: 10.1016/j.neuron.2004.05.003  1
2004 Saura CA, Choi SY, Beglopoulos V, Malkani S, Zhang D, Shankaranarayana Rao BS, Chattarji S, Kelleher RJ, Kandel ER, Duff K, Kirkwood A, Shen J. Loss of presenilin function causes impairments of memory and synaptic plasticity followed by age-dependent neurodegeneration. Neuron. 42: 23-36. PMID 15066262 DOI: 10.1016/S0896-6273(04)00182-5  1
2003 Morales B, Rozas C, Pancetti F, Kirkwood A. [Critical period of cortical plasticity]. Revista De Neurologia. 37: 739-43. PMID 14593633  1
2003 Gianfranceschi L, Siciliano R, Walls J, Morales B, Kirkwood A, Huang ZJ, Tonegawa S, Maffei L. Visual cortex is rescued from the effects of dark rearing by overexpression of BDNF. Proceedings of the National Academy of Sciences of the United States of America. 100: 12486-91. PMID 14514885 DOI: 10.1073/pnas.1934836100  1
2002 Morales B, Choi SY, Kirkwood A. Dark rearing alters the development of GABAergic transmission in visual cortex. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 8084-90. PMID 12223562  1
2002 Choi SY, Morales B, Lee HK, Kirkwood A. Absence of long-term depression in the visual cortex of glutamic Acid decarboxylase-65 knock-out mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 5271-6. PMID 12097476  1
2001 Yu H, Saura CA, Choi SY, Sun LD, Yang X, Handler M, Kawarabayashi T, Younkin L, Fedeles B, Wilson MA, Younkin S, Kandel ER, Kirkwood A, Shen J. APP processing and synaptic plasticity in presenilin-1 conditional knockout mice. Neuron. 31: 713-26. PMID 11567612 DOI: 10.1016/S0896-6273(01)00417-2  1
2001 Rozas C, Frank H, Heynen AJ, Morales B, Bear MF, Kirkwood A. Developmental inhibitory gate controls the relay of activity to the superficial layers of the visual cortex. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 6791-801. PMID 11517267  1
2001 Frankland PW, O'Brien C, Ohno M, Kirkwood A, Silva AJ. Alpha-CaMKII-dependent plasticity in the cortex is required for permanent memory. Nature. 411: 309-13. PMID 11357133 DOI: 10.1038/35077089  1
2000 Kirkwood A. Serotonergic control of developmental plasticity. Proceedings of the National Academy of Sciences of the United States of America. 97: 1951-2. PMID 10688919 DOI: 10.1073/pnas.070044697  1
1999 Huang ZJ, Kirkwood A, Pizzorusso T, Porciatti V, Morales B, Bear MF, Maffei L, Tonegawa S. BDNF regulates the maturation of inhibition and the critical period of plasticity in mouse visual cortex. Cell. 98: 739-55. PMID 10499792 DOI: 10.1016/S0092-8674(00)81509-3  1
1999 Kirkwood A, Rozas C, Kirkwood J, Perez F, Bear MF. Modulation of long-term synaptic depression in visual cortex by acetylcholine and norepinephrine. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 1599-609. PMID 10024347  1
1997 Kirkwood A, Silva A, Bear MF. Age-dependent decrease of synaptic plasticity in the neocortex of alphaCaMKII mutant mice. Proceedings of the National Academy of Sciences of the United States of America. 94: 3380-3. PMID 9096402 DOI: 10.1073/pnas.94.7.3380  1
1996 Aizenman CD, Kirkwood A, Bear MF. A current source density analysis of evoked responses in slices of adult rat visual cortex: implications for the regulation of long-term potentiation. Cerebral Cortex (New York, N.Y. : 1991). 6: 751-8. PMID 8922331 DOI: 10.1093/cercor/6.6.751  1
1996 Kirkwood A, Rioult MC, Bear MF. Experience-dependent modification of synaptic plasticity in visual cortex. Nature. 381: 526-8. PMID 8632826 DOI: 10.1038/381526a0  1
1995 Kirkwood A, Bear MF. Elementary forms of synaptic plasticity in the visual cortex. Biological Research. 28: 73-80. PMID 8728822  1
1995 Kirkwood A, Lee HK, Bear MF. Co-regulation of long-term potentiation and experience-dependent synaptic plasticity in visual cortex by age and experience. Nature. 375: 328-31. PMID 7753198 DOI: 10.1038/375328a0  1
1994 Kirkwood A, Bear MF. Homosynaptic long-term depression in the visual cortex. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 14: 3404-12. PMID 8182481  1
1994 Kirkwood A, Bear MF. Hebbian synapses in visual cortex. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 14: 1634-45. PMID 8126560  1
1994 Kirkwood A, Lisman JE. Determinants of single photon response variability. The Journal of General Physiology. 103: 679-90. PMID 8057084  1
1993 Bear MF, Kirkwood A. Neocortical long-term potentiation. Current Opinion in Neurobiology. 3: 197-202. PMID 8513232 DOI: 10.1016/0959-4388(93)90210-P  1
1993 Kirkwood A, Dudek SM, Gold JT, Aizenman CD, Bear MF. Common forms of synaptic plasticity in the hippocampus and neocortex in vitro. Science (New York, N.Y.). 260: 1518-21. PMID 8502997  1
1992 Lisman J, Erickson MA, Richard EA, Cote RH, Bacigalupo J, Johnson E, Kirkwood A. Mechanisms of amplification, deactivation, and noise reduction in invertebrate photoreceptors. Society of General Physiologists Series. 47: 175-99. PMID 1369761  1
1992 Kirkwood A, Lisman JE. Action potentials produce a long-term enhancement of M-current in frog sympathetic ganglion. Brain Research. 580: 281-7. PMID 1354558 DOI: 10.1016/0006-8993(92)90955-9  1
1991 Kirkwood A, Simmons MA, Mather RJ, Lisman J. Muscarinic suppression of the M-current is mediated by a rise in internal Ca2+ concentration. Neuron. 6: 1009-14. PMID 1905146 DOI: 10.1016/0896-6273(91)90240-Z  1
1989 Kirkwood A, Weiner D, Lisman JE. An estimate of the number of G regulator proteins activated per excited rhodopsin in living Limulus ventral photoreceptors. Proceedings of the National Academy of Sciences of the United States of America. 86: 3872-6. PMID 2498877  1
1986 Golowasch J, Kirkwood A, Miller C. Allosteric effects of Mg2+ on the gating of Ca2+-activated K+ channels from mammalian skeletal muscle. The Journal of Experimental Biology. 124: 5-13. PMID 2428908  1
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