| Year |
Citation |
Score |
| 2024 |
Kim S, Yu H, Azam T, Dinarello CA. Interleukin-18 Binding Protein (IL-18BP): A Long Journey From Discovery to Clinical Application. Immune Network. 24: e1. PMID 38455460 DOI: 10.4110/in.2024.24.e1 |
0.33 |
|
| 2023 |
Dinarello A, May M, Amo-Aparicio J, Azam T, Gaballa JM, Marchetti C, Tesoriere A, Ghirardo R, Redzic JS, Webber WS, Atif SM, Li S, Eisenmesser EZ, de Graaf DM, Dinarello CA. IL-38 regulates intestinal stem cell homeostasis by inducing WNT signaling and beneficial IL-1β secretion. Proceedings of the National Academy of Sciences of the United States of America. 120: e2306476120. PMID 37906644 DOI: 10.1073/pnas.2306476120 |
0.641 |
|
| 2023 |
Tengesdal IW, Dinarello CA, Marchetti C. NLRP3 and cancer: Pathogenesis and therapeutic opportunities. Pharmacology & Therapeutics. 251: 108545. PMID 37866732 DOI: 10.1016/j.pharmthera.2023.108545 |
0.553 |
|
| 2023 |
Amo-Aparicio J, Dominguez A, Atif SM, Dinarello A, Azam T, Alula KM, Piper M, Lieu CH, Lentz RW, Leal AD, Bagby SM, Messersmith WA, Karam SD, Dinarello CA, Pitts TM, et al. Pancreatic Ductal Adenocarcinoma Cells Regulate NLRP3 Activation to Generate a Tolerogenic Microenvironment. Cancer Research Communications. 3: 1899-1911. PMID 37772994 DOI: 10.1158/2767-9764.CRC-23-0065 |
0.475 |
|
| 2023 |
The E, Zhai Y, Yao Q, Ao L, Li S, Fullerton DA, Dinarello CA, Meng X. Recombinant IL-37 Exerts an Anti-inflammatory Effect on Human Aortic Valve Interstitial Cells through Extracellular and Intracellular Actions. International Journal of Biological Sciences. 19: 3908-3919. PMID 37564205 DOI: 10.7150/ijbs.85745 |
0.655 |
|
| 2023 |
Amo-Aparicio J, Daly J, Højen JF, Dinarello CA. Pharmacologic inhibition of NLRP3 reduces the levels of α-synuclein and protects dopaminergic neurons in a model of Parkinson's disease. Journal of Neuroinflammation. 20: 147. PMID 37349821 DOI: 10.1186/s12974-023-02830-w |
0.375 |
|
| 2023 |
Ghezzi P, Fantuzzi G, Dinarello CA. Perspective: Daniela Novick, cytokines and their receptors. Frontiers in Immunology. 14: 1160651. PMID 37251377 DOI: 10.3389/fimmu.2023.1160651 |
0.607 |
|
| 2023 |
Teufel LU, Netea MG, van de Veerdonk FL, Dinarello CA, Joosten LAB, Arts RJW. Opposing Effects of Interleukin-36γ and Interleukin-38 on Trained Immunity. International Journal of Molecular Sciences. 24. PMID 36768634 DOI: 10.3390/ijms24032311 |
0.634 |
|
| 2023 |
Dinarello A, Mills TS, Tengesdal IW, Powers NE, Azam T, Dinarello CA. Dexamethasone and OLT1177 Cooperate in the Reduction of Melanoma Growth by Inhibiting STAT3 Functions. Cells. 12. PMID 36672229 DOI: 10.3390/cells12020294 |
0.524 |
|
| 2022 |
de Graaf DM, Teufel LU, de Nooijer AH, van Gammeren AJ, Ermens AAM, Gaál IO, Crișan TO, van de Veerdonk FL, Netea MG, Dinarello CA, Joosten LAB, Arts RJW. Exploratory analysis of interleukin-38 in hospitalized COVID-19 patients. Immunity, Inflammation and Disease. 10: e712. PMID 36301025 DOI: 10.1002/iid3.712 |
0.64 |
|
| 2022 |
Lonnemann N, Hosseini S, Ohm M, Geffers R, Hiller K, Dinarello CA, Korte M. IL-37 expression reduces acute and chronic neuroinflammation and rescues cognitive impairment in an Alzheimer's disease mouse model. Elife. 11. PMID 36040311 DOI: 10.7554/eLife.75889 |
0.636 |
|
| 2022 |
The E, de Graaf DM, Zhai Y, Yao Q, Ao L, Fullerton DA, Dinarello CA, Meng X. Interleukin 38 alleviates aortic valve calcification by inhibition of NLRP3. Proceedings of the National Academy of Sciences of the United States of America. 119: e2202577119. PMID 36037361 DOI: 10.1073/pnas.2202577119 |
0.607 |
|
| 2022 |
Teufel LU, de Graaf DM, Netea MG, Dinarello CA, Joosten LAB, Arts RJW. Circulating interleukin-38 concentrations in healthy adults. Frontiers in Immunology. 13: 964365. PMID 36016926 DOI: 10.3389/fimmu.2022.964365 |
0.623 |
|
| 2022 |
Lee E, Redzic JS, Nemkov T, Saviola AJ, Dzieciatkowska M, Hansen KC, D'Alessandro A, Dinarello C, Eisenmesser EZ. Human and Bacterial Toll-Interleukin Receptor Domains Exhibit Distinct Dynamic Features and Functions. Molecules (Basel, Switzerland). 27. PMID 35889366 DOI: 10.3390/molecules27144494 |
0.403 |
|
| 2022 |
de Graaf DM, Wang RX, Amo-Aparicio J, Lee JS, Dowdell AS, Tengesdal IW, Marchetti C, Colgan SP, Joosten LAB, Dinarello CA. IL-38 Gene Deletion Worsens Murine Colitis. Frontiers in Immunology. 13: 840719. PMID 35693797 DOI: 10.3389/fimmu.2022.840719 |
0.65 |
|
| 2022 |
Tengesdal IW, Li S, Powers NE, May M, Neff CP, Joosten LAB, Marchetti C, Dinarello CA. Activation of Host-NLRP3 Inflammasome in Myeloid Cells Dictates Response to Anti-PD-1 Therapy in Metastatic Breast Cancers. Pharmaceuticals (Basel, Switzerland). 15. PMID 35631400 DOI: 10.3390/ph15050574 |
0.44 |
|
| 2022 |
Brunt VE, Ikoba AP, Ziemba BP, Ballak DB, Hoischen A, Dinarello CA, Ehringer MA, Seals DR. Circulating interleukin-37 declines with aging in healthy humans: relations to healthspan indicators and IL37 gene SNPs. Geroscience. PMID 35622271 DOI: 10.1007/s11357-022-00587-3 |
0.598 |
|
| 2022 |
de Graaf DM, Teufel LU, Joosten LAB, Dinarello CA. Interleukin-38 in Health and Disease. Cytokine. 152: 155824. PMID 35220115 DOI: 10.1016/j.cyto.2022.155824 |
0.389 |
|
| 2021 |
van de Veerdonk FL, Renga G, Pariano M, Bellet MM, Servillo G, Fallarino F, De Luca A, Iannitti RG, Piobbico D, Gargaro M, Manni G, D'Onofrio F, Stincardini C, Sforna L, Borghi M, ... ... Dinarello CA, et al. Anakinra restores cellular proteostasis by coupling mitochondrial redox balance to autophagy. The Journal of Clinical Investigation. PMID 34847078 DOI: 10.1172/JCI144983 |
0.572 |
|
| 2021 |
Teufel LU, Arts RJW, Netea MG, Dinarello CA, Joosten LAB. IL-1 family cytokines as drivers and inhibitors of trained immunity. Cytokine. 150: 155773. PMID 34844039 DOI: 10.1016/j.cyto.2021.155773 |
0.583 |
|
| 2021 |
Lunding LP, Skouras DB, Vock C, Dinarello CA, Wegmann M. The NLRP3 inflammasome inhibitor, OLT1177 , ameliorates experimental allergic asthma in mice. Allergy. PMID 34716997 DOI: 10.1111/all.15164 |
0.36 |
|
| 2021 |
Amo-Aparicio J, Garcia-Garcia J, Puigdomenech M, Francos-Quijorna I, Skouras DB, Dinarello CA, Lopez-Vales R. Inhibition of the NLRP3 inflammasome by OLT1177 induces functional protection and myelin preservation after spinal cord injury. Experimental Neurology. 347: 113889. PMID 34624330 DOI: 10.1016/j.expneurol.2021.113889 |
0.584 |
|
| 2021 |
Tengesdal IW, Dinarello A, Powers NE, Burchill MA, Joosten LAB, Marchetti C, Dinarello CA. Tumor NLRP3-Derived IL-1β Drives the IL-6/STAT3 Axis Resulting in Sustained MDSC-Mediated Immunosuppression. Frontiers in Immunology. 12: 661323. PMID 34531850 DOI: 10.3389/fimmu.2021.661323 |
0.603 |
|
| 2021 |
Schröder A, Lunding LP, Zissler UM, Vock C, Webering S, Ehlers JC, Orinska Z, Chaker A, Schmidt-Weber CB, Lang NJ, Schiller HB, Mall MA, Fehrenbach H, Dinarello CA, Wegmann M. IL-37 regulates allergic inflammation by counterbalancing pro-inflammatory IL-1 and IL-33. Allergy. PMID 34460953 DOI: 10.1111/all.15072 |
0.619 |
|
| 2021 |
Javan H, Li L, Schaaf CL, Lee YS, Salama ME, Dinarello CA, Selzman CH. Interleukin 1 receptor antagonism abrogates acute pressure-overload induced murine heart failure. The Annals of Thoracic Surgery. PMID 34419440 DOI: 10.1016/j.athoracsur.2021.07.044 |
0.494 |
|
| 2021 |
Zhao P, Yao Q, Zhang PJ, The E, Zhai Y, Ao L, Jarrett MJ, Dinarello CA, Fullerton DA, Meng X. Single-cell RNA-seq reveals a critical role of novel pro-inflammatory EndMT in mediating adverse remodeling in coronary artery-on-a-chip. Science Advances. 7. PMID 34417174 DOI: 10.1126/sciadv.abg1694 |
0.463 |
|
| 2021 |
Briukhovetska D, Dörr J, Endres S, Libby P, Dinarello CA, Kobold S. Interleukins in cancer: from biology to therapy. Nature Reviews. Cancer. PMID 34083781 DOI: 10.1038/s41568-021-00363-z |
0.451 |
|
| 2021 |
Biavasco R, Molteni R, Stefanoni D, Nemkov T, Netea MG, Domínguez-Andrés J, Arts RJ, Merelli I, Mazza D, Zambrano S, Panigada M, Cantoni E, Tengesdal I, Maksud P, Piras F, ... ... Dinarello CA, et al. Oncogene-induced maladaptive activation of trained immunity in the pathogenesis and treatment of Erdheim-Chester disease. Blood. PMID 34077954 DOI: 10.1182/blood.2020009594 |
0.495 |
|
| 2021 |
Pizarro TT, Dinarello CA, Cominelli F. Editorial: Cytokines and Intestinal Mucosal Immunity. Frontiers in Immunology. 12: 698693. PMID 34054881 DOI: 10.3389/fimmu.2021.698693 |
0.427 |
|
| 2021 |
van Deuren RC, Arts P, Cavalli G, Jaeger M, Steehouwer M, van de Vorst M, Gilissen C, Joosten LAB, Dinarello CA, Mhlanga MM, Kumar V, Netea MG, van de Veerdonk FL, Hoischen A. Impact of rare and common genetic variation in the interleukin-1 pathway on human cytokine responses. Genome Medicine. 13: 94. PMID 34034819 DOI: 10.1186/s13073-021-00907-w |
0.516 |
|
| 2021 |
Kouwenberg M, Pulskens WPC, Diepeveen L, Bakker-van Bebber M, Dinarello CA, Netea MG, Hilbrands LB, van der Vlag J. Reduced CXCL1 production by endogenous IL-37 expressing dendritic cells does not affect T cell activation. Plos One. 16: e0251809. PMID 34029331 DOI: 10.1371/journal.pone.0251809 |
0.332 |
|
| 2021 |
Cavalli G, Tengesdal IW, Gresnigt M, Nemkov T, Arts RJW, Domínguez-Andrés J, Molteni R, Stefanoni D, Cantoni E, Cassina L, Giugliano S, Schraa K, Mills TS, Pietras EM, Eisenmensser EZ, ... ... Dinarello CA, et al. The anti-inflammatory cytokine interleukin-37 is an inhibitor of trained immunity. Cell Reports. 35: 108955. PMID 33826894 DOI: 10.1016/j.celrep.2021.108955 |
0.59 |
|
| 2021 |
Li S, Jiang L, Beckmann K, Højen JF, Pessara U, Powers NE, de Graaf DM, Azam T, Lindenberger J, Eisenmesser EZ, Fischer S, Dinarello CA. A novel anti-human IL-1R7 antibody reduces IL-18-mediated inflammatory signaling. The Journal of Biological Chemistry. 100630. PMID 33823154 DOI: 10.1016/j.jbc.2021.100630 |
0.655 |
|
| 2021 |
Mountford S, Effenberger M, Noll-Puchta H, Griessmair L, Ringleb A, Haas S, Denk G, Reiter FP, Mayr D, Dinarello CA, Tilg H, Bufler P. Modulation of Liver Inflammation and Fibrosis by Interleukin-37. Frontiers in Immunology. 12: 603649. PMID 33746950 DOI: 10.3389/fimmu.2021.603649 |
0.606 |
|
| 2021 |
Tengesdal IW, Menon DR, Osborne DG, Neff CP, Powers NE, Gamboni F, Mauro AG, D'Alessandro A, Stefanoni D, Henen MA, Mills TS, De Graaf DM, Azam T, Vogeli B, Palmer BE, ... ... Dinarello CA, et al. Targeting tumor-derived NLRP3 reduces melanoma progression by limiting MDSCs expansion. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33649199 DOI: 10.1073/pnas.2000915118 |
0.549 |
|
| 2021 |
van der Heijden WA, van de Wijer L, Keramati F, Trypsteen W, Rutsaert S, Ter Horst R, Jaeger M, Koenen HJ, Stunnenberg HG, Joosten I, Verweij PE, van Lunzen J, Dinarello CA, Joosten LA, Vandekerckhove L, et al. Chronic HIV infection induces transcriptional and functional reprogramming of innate immune cells. Jci Insight. PMID 33630761 DOI: 10.1172/jci.insight.145928 |
0.538 |
|
| 2021 |
de Graaf DM, Teufel LU, van de Veerdonk FL, Joosten LAB, Netea MG, Dinarello CA, Arts RJW. IL-38 prevents induction of trained immunity by inhibition of mTOR signaling. Journal of Leukocyte Biology. PMID 33620105 DOI: 10.1002/JLB.3A0220-143RRR |
0.588 |
|
| 2021 |
Cavalli G, Colafrancesco S, Emmi G, Imazio M, Lopalco G, Maggio MC, Sota J, Dinarello CA. Interleukin 1α: a comprehensive review on the role of IL-1α in the pathogenesis and targeted treatment of autoimmune and inflammatory diseases. Autoimmunity Reviews. 102763. PMID 33482337 DOI: 10.1016/j.autrev.2021.102763 |
0.644 |
|
| 2021 |
Hamilton JAG, Lee MY, Hunter R, Ank RS, Story JY, Talekar G, Sisroe T, Ballak DB, Fedanov A, Porter CC, Eisenmesser EZ, Dinarello CA, Raikar SS, DeGregori J, Henry CJ. Interleukin-37 improves T-cell-mediated immunity and chimeric antigen receptor T-cell therapy in aged backgrounds. Aging Cell. e13309. PMID 33480151 DOI: 10.1111/acel.13309 |
0.542 |
|
| 2021 |
Sánchez-Fernández A, Zandee S, Amo-Aparicio J, Charabati M, Prat A, Garlanda C, Eisenmesser EZ, Dinarello CA, López-Vales R. IL-37 exerts therapeutic effects in experimental autoimmune encephalomyelitis through the receptor complex IL-1R5/IL-1R8. Theranostics. 11: 1-13. PMID 33391457 DOI: 10.7150/thno.47435 |
0.626 |
|
| 2020 |
Netea MG, Balkwill F, Chonchol M, Cominelli F, Donath MY, Giamarellos-Bourboulis EJ, Golenbock D, Gresnigt MS, Heneka MT, Hoffman HM, Hotchkiss R, Joosten LAB, Kastner DL, Korte M, Latz E, ... ... Dinarello CA, et al. Author Correction: A guiding map for inflammation. Nature Immunology. PMID 33288963 DOI: 10.1038/s41590-020-00846-5 |
0.346 |
|
| 2020 |
Lonnemann N, Hosseini S, Marchetti C, Skouras DB, Stefanoni D, D'Alessandro A, Dinarello CA, Korte M. The NLRP3 inflammasome inhibitor OLT1177 rescues cognitive impairment in a mouse model of Alzheimer's disease. Proceedings of the National Academy of Sciences of the United States of America. PMID 33257576 DOI: 10.1073/pnas.2009680117 |
0.506 |
|
| 2020 |
Rønholt K, Nielsen AL, Johansen C, Vestergaard C, Fauerbye A, López-Vales R, Dinarello CA, Iversen L. IL-37 Expression Is Downregulated in Lesional Psoriasis Skin. Immunohorizons. 4: 754-761. PMID 33239358 DOI: 10.4049/immunohorizons.2000083 |
0.63 |
|
| 2020 |
de Graaf DM, Maas RJA, Smeekens SP, Eisenmesser E, Redzic JS, Helsen MM, Powers NE, Li S, Kalabokis V, Gresnigt MS, Joosten LAB, Dinarello CA, van de Veerdonk FL. Human recombinant interleukin-38 suppresses inflammation in mouse models of local and systemic disease. Cytokine. 137: 155334. PMID 33128926 DOI: 10.1016/j.cyto.2020.155334 |
0.66 |
|
| 2020 |
de Graaf DM, Jaeger M, van den Munckhof ICL, Horst RT, Schraa K, Zwaag J, Kox M, Fujita M, Yamauchi T, Mercurio L, Madonna S, Rutten JHW, de Graaf J, Riksen NP, van de Veerdonk FL, ... ... Dinarello CA, et al. Reduced concentrations of the B cell cytokine Interleukin 38 are associated with cardiovascular disease risk in overweight subjects. European Journal of Immunology. PMID 33125159 DOI: 10.1002/eji.201948390 |
0.644 |
|
| 2020 |
Klück V, Jansen TLTA, Janssen M, Comarniceanu A, Efdé M, Tengesdal IW, Schraa K, Cleophas MCP, Scribner CL, Skouras DB, Marchetti C, Dinarello CA, Joosten LAB. Dapansutrile, an oral selective NLRP3 inflammasome inhibitor, for treatment of gout flares: an open-label, dose-adaptive, proof-of-concept, phase 2a trial. The Lancet Rheumatology. 2: e270-e280. PMID 33005902 DOI: 10.1016/s2665-9913(20)30065-5 |
0.349 |
|
| 2020 |
Amo-Aparicio J, Sanchez-Fernandez A, Li S, Eisenmesser EZ, Garlanda C, Dinarello CA, Lopez-Vales R. Extracellular and nuclear roles of IL-37 after spinal cord injury. Brain, Behavior, and Immunity. PMID 33002630 DOI: 10.1016/j.bbi.2020.09.026 |
0.645 |
|
| 2020 |
Zhai Z, Samson JM, Yamauchi T, Vaddi PK, Matsumoto Y, Dinarello CA, Ravindran Menon D, Fujita M. Inflammasome Sensor NLRP1 Confers Acquired Drug Resistance to Temozolomide in Human Melanoma. Cancers. 12. PMID 32899791 DOI: 10.3390/Cancers12092518 |
0.58 |
|
| 2020 |
Vecchié A, Bonaventura A, Toldo S, Dagna L, Dinarello CA, Abbate A. IL-18 and infections: Is there a role for targeted therapies? Journal of Cellular Physiology. PMID 32794180 DOI: 10.1002/Jcp.30008 |
0.694 |
|
| 2020 |
Cauchois R, Koubi M, Delarbre D, Manet C, Carvelli J, Blasco VB, Jean R, Fouche L, Bornet C, Pauly V, Mazodier K, Pestre V, Jarrot PA, Dinarello CA, Kaplanski G. Early IL-1 receptor blockade in severe inflammatory respiratory failure complicating COVID-19. Proceedings of the National Academy of Sciences of the United States of America. PMID 32699149 DOI: 10.1073/Pnas.2009017117 |
0.614 |
|
| 2020 |
Grander C, Schaefer B, Schwärzler J, Grabherr F, de Graaf DM, Enrich B, Oberhuber G, Mayr L, Sangineto M, Jaschke N, Adolph TE, Effenberger M, Moschen AR, Dinarello CA, Zoller H, et al. Alpha-1 antitrypsin governs alcohol-related liver disease in mice and humans. Gut. PMID 32699098 DOI: 10.1136/Gutjnl-2020-321375 |
0.467 |
|
| 2020 |
Abbate A, Toldo S, Marchetti C, Kron J, Van Tassell BW, Dinarello CA. Interleukin-1 and the Inflammasome as Therapeutic Targets in Cardiovascular Disease. Circulation Research. 126: 1260-1280. PMID 32324502 DOI: 10.1161/Circresaha.120.315937 |
0.677 |
|
| 2020 |
Klück V, van Deuren RC, Cavalli G, Shaukat A, Arts P, Cleophas MC, Crișan TO, Tausche AK, Riches P, Dalbeth N, Stamp LK, Hindmarsh JH, Jansen TLTA, Janssen M, Steehouwer M, ... ... Dinarello CA, et al. Rare genetic variants in interleukin-37 link this anti-inflammatory cytokine to the pathogenesis and treatment of gout. Annals of the Rheumatic Diseases. PMID 32114511 DOI: 10.1136/Annrheumdis-2019-216233 |
0.676 |
|
| 2019 |
Menghini P, Corridoni D, Buttó LF, Osme A, Shivaswamy S, Lam M, Bamias G, Pizarro TT, Rodriguez-Palacios A, Dinarello CA, Cominelli F. Neutralization of IL-1α ameliorates Crohn's disease-like ileitis by functional alterations of the gut microbiome. Proceedings of the National Academy of Sciences of the United States of America. PMID 31843928 DOI: 10.1073/Pnas.1915043116 |
0.668 |
|
| 2019 |
Powers NE, Swartzwelter B, Marchetti C, de Graaf DM, Lerchner A, Schlapschy M, Datar R, Binder U, Edwards CK, Skerra A, Dinarello CA. PASylation of IL-1 Receptor antagonist (IL-1Ra) retains IL-1 blockade and extends its duration in mouse urate crystal-induced peritonitis. The Journal of Biological Chemistry. PMID 31819009 DOI: 10.1074/Jbc.Ra119.010340 |
0.646 |
|
| 2019 |
Mountford S, Ringleb A, Schwaiger R, Mayr D, Kobold S, Dinarello CA, Bufler P. Interleukin-37 Inhibits Colon Carcinogensis During Chronic Colitis. Frontiers in Immunology. 10: 2632. PMID 31781119 DOI: 10.3389/Fimmu.2019.02632 |
0.688 |
|
| 2019 |
Ballak DB, Brunt VE, Sapinsley ZJ, Ziemba BP, Richey JJ, Zigler MC, Johnson LC, Gioscia-Ryan RA, Culp-Hill R, Eisenmesser EZ, D'Alessandro A, Dinarello CA, Seals DR. Short-term interleukin-37 treatment improves vascular endothelial function, endurance exercise capacity, and whole-body glucose metabolism in old mice. Aging Cell. e13074. PMID 31755162 DOI: 10.1111/Acel.13074 |
0.608 |
|
| 2019 |
Sánchez-Fernández A, Skouras DB, Dinarello CA, López-Vales R. OLT1177 (Dapansutrile), a Selective NLRP3 Inflammasome Inhibitor, Ameliorates Experimental Autoimmune Encephalomyelitis Pathogenesis. Frontiers in Immunology. 10: 2578. PMID 31736980 DOI: 10.3389/Fimmu.2019.02578 |
0.655 |
|
| 2019 |
Dinarello CA. The IL-1 family of cytokines and receptors in rheumatic diseases. Nature Reviews Rheumatology. 15: 612-632. PMID 31515542 DOI: 10.1038/S41584-019-0277-8 |
0.691 |
|
| 2019 |
Donath MY, Dinarello CA, Mandrup-Poulsen T. Targeting innate immune mediators in type 1 and type 2 diabetes. Nature Reviews. Immunology. PMID 31501536 DOI: 10.1038/S41577-019-0213-9 |
0.456 |
|
| 2019 |
Højen JF, Kristensen MLV, McKee AS, Wade MT, Azam T, Lunding LP, de Graaf DM, Swartzwelter BJ, Wegmann M, Tolstrup M, Beckman K, Fujita M, Fischer S, Dinarello CA. IL-1R3 blockade broadly attenuates the functions of six members of the IL-1 family, revealing their contribution to models of disease. Nature Immunology. PMID 31427775 DOI: 10.1038/S41590-019-0467-1 |
0.685 |
|
| 2019 |
Madonna S, Girolomoni G, Dinarello CA, Albanesi C. The Significance of IL-36 Hyperactivation and IL-36R Targeting in Psoriasis. International Journal of Molecular Sciences. 20. PMID 31284527 DOI: 10.3390/Ijms20133318 |
0.699 |
|
| 2019 |
Hernandez G, Mills TS, Rabe JL, Chavez JS, Kuldanek S, Kirkpatrick G, Noetzli L, Jubair WK, Zanche M, Meyers JR, Stevens BM, Fleenor CJ, Adane B, Dinarello CA, Ashton J, et al. Pro-inflammatory cytokine blockade attenuates myeloid expansion in a murine model of rheumatoid arthritis. Haematologica. PMID 31101752 DOI: 10.3324/Haematol.2018.197210 |
0.52 |
|
| 2019 |
Osborne DG, Domenico J, Luo Y, Reid AL, Amato C, Zhai Z, Gao D, Ziman M, Dinarello CA, Robinson WA, Fujita M. Interleukin-37 is highly expressed in regulatory T cells of melanoma patients and enhanced by melanoma cell secretome. Molecular Carcinogenesis. PMID 31099111 DOI: 10.1002/Mc.23044 |
0.669 |
|
| 2019 |
Mantovani A, Dinarello CA, Molgora M, Garlanda C. Interleukin-1 and Related Cytokines in the Regulation of Inflammation and Immunity. Immunity. 50: 778-795. PMID 30995499 DOI: 10.1016/J.Immuni.2019.03.012 |
0.679 |
|
| 2019 |
Cavalli G, Dinarello CA. Corrigendum: Anakinra Therapy for Non-cancer Inflammatory Diseases. Frontiers in Pharmacology. 10: 148. PMID 30906259 DOI: 10.3389/Fphar.2019.00148 |
0.45 |
|
| 2019 |
Eisenmesser EZ, Gottschlich A, Redzic JS, Paukovich N, Nix JC, Azam T, Zhang L, Zhao R, Kieft JS, The E, Meng X, Dinarello CA. Interleukin-37 monomer is the active form for reducing innate immunity. Proceedings of the National Academy of Sciences of the United States of America. PMID 30819901 DOI: 10.1073/Pnas.1819672116 |
0.691 |
|
| 2019 |
Cavalli G, Tomelleri A, De Luca G, Campochiaro C, Dinarello CA, Baldissera E, Dagna L. Correction to: Efficacy of canakinumab as first-line biologic agent in adult-onset Still's disease. Arthritis Research & Therapy. 21: 69. PMID 30803447 DOI: 10.1186/S13075-019-1850-X |
0.425 |
|
| 2019 |
Li S, Amo-Aparicio J, Neff CP, Tengesdal IW, Azam T, Palmer BE, López-Vales R, Bufler P, Dinarello CA. Role for nuclear interleukin-37 in the suppression of innate immunity. Proceedings of the National Academy of Sciences of the United States of America. PMID 30792349 DOI: 10.1073/Pnas.1821111116 |
0.697 |
|
| 2019 |
Cavalli G, Tomelleri A, De Luca G, Campochiaro C, Dinarello CA, Baldissera E, Dagna L. Efficacy of canakinumab as first-line biologic agent in adult-onset Still's disease. Arthritis Research & Therapy. 21: 54. PMID 30760322 DOI: 10.1186/S13075-019-1843-9 |
0.429 |
|
| 2019 |
Cleophas MCP, Crişan TO, Klück V, Hoogerbrugge N, Netea-Maier RT, Dinarello CA, Netea MG, Joosten LAB. Romidepsin suppresses monosodium urate crystal-induced cytokine production through upregulation of suppressor of cytokine signaling 1 expression. Arthritis Research & Therapy. 21: 50. PMID 30728075 DOI: 10.1186/S13075-019-1834-X |
0.537 |
|
| 2019 |
Kurzrock R, Hickish T, Wyrwicz L, Saunders M, Wu Q, Stecher M, Mohanty P, Dinarello CA, Simard J. Interleukin-1 receptor antagonist levels predict favorable outcome after bermekimab, a first-in-class true human interleukin-1α antibody, in a phase III randomized study of advanced colorectal cancer. Oncoimmunology. 8: 1551651. PMID 30723583 DOI: 10.1080/2162402X.2018.1551651 |
0.659 |
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| 2019 |
Cavalli G, Gresnigt M, Nemkov T, Arts R, D’Alessandro A, Giugliano S, Eisenmensser E, Dagna L, Joosten L, Netea M, Dinarello C. P087 The anti-inflammatory cytokine interleukin 37 is an endogenous inhibitor of trained immunity Annals of the Rheumatic Diseases. 78. DOI: 10.1136/Annrheumdis-2018-Ewrr2019.76 |
0.528 |
|
| 2019 |
Jansen T, Klück V, Janssen M, Comarniceanu A, Efdé M, Scribner C, Barrow R, Skouras D, Dinarello C, Joosten L. P160 The first phase 2A proof-of-concept study of a selective NLRP3 inflammasome inhibitor, dapansutrile™ (OLT1177™), in acute gout Annals of the Rheumatic Diseases. 78. DOI: 10.1136/Annrheumdis-2018-Ewrr2019.142 |
0.374 |
|
| 2019 |
Klück V, Janssen M, Jansen T, Tengesdal I, Schraa K, Skouras D, Marchetti C, Dinarello C, Joosten L. P159/O30 OLT1177™, an oral NLRP3 inflammasome inhibitor, inhibits acute joint inflammation and circulating IL 1β during gout flares in humans Annals of the Rheumatic Diseases. 78. DOI: 10.1136/Annrheumdis-2018-Ewrr2019.141 |
0.558 |
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| 2019 |
Vaddi P, Luo Y, Dinarello C, Fujita M. 527 Uncovering molecular mechanisms involved in the IL-37-mediated tolerogenic dendritic cells Journal of Investigative Dermatology. 139: S90. DOI: 10.1016/J.JID.2019.03.603 |
0.402 |
|
| 2018 |
Dinarello CA. Treatment of Inflammatory Diseases with IL-1 Blockade. Current Otorhinolaryngology Reports. 6: 1-14. PMID 33133777 DOI: 10.1007/S40136-018-0181-9 |
0.656 |
|
| 2018 |
Voronov E, Dinarello CA, Apte RN. Interleukin-1α as an intracellular alarmin in cancer biology. Seminars in Immunology. 38: 3-14. PMID 30554608 DOI: 10.1016/J.Smim.2018.10.006 |
0.474 |
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| 2018 |
Kaplanov I, Carmi Y, Kornetsky R, Shemesh A, Shurin GV, Shurin MR, Dinarello CA, Voronov E, Apte RN. Blocking IL-1β reverses the immunosuppression in mouse breast cancer and synergizes with anti-PD-1 for tumor abrogation. Proceedings of the National Academy of Sciences of the United States of America. PMID 30545915 DOI: 10.1073/Pnas.1812266115 |
0.632 |
|
| 2018 |
Cavalli G, Dinarello CA. Anakinra Therapy for Non-cancer Inflammatory Diseases. Frontiers in Pharmacology. 9: 1157. PMID 30459597 DOI: 10.3389/Fphar.2018.01157 |
0.694 |
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| 2018 |
Tunjungputri RN, Li Y, de Groot PG, Dinarello CA, Smeekens SP, Jaeger M, Doppenberg-Oosting M, Cruijsen M, Lemmers H, Toenhake-Dijkstra H, Aguirre-Gamboa R, Kumar V, Wijmenga C, Joosten LAB, Netea MG, et al. The Inter-Relationship of Platelets with Interleukin-1β-Mediated Inflammation in Humans. Thrombosis and Haemostasis. PMID 30453346 DOI: 10.1055/S-0038-1675603 |
0.625 |
|
| 2018 |
Mercurio L, Morelli M, Scarponi C, Eisenmesser EZ, Doti N, Pagnanelli G, Gubinelli E, Mazzanti C, Cavani A, Ruvo M, Dinarello CA, Albanesi C, Madonna S. IL-38 has an anti-inflammatory action in psoriasis and its expression correlates with disease severity and therapeutic response to anti-IL-17A treatment. Cell Death & Disease. 9: 1104. PMID 30377293 DOI: 10.1038/S41419-018-1143-3 |
0.697 |
|
| 2018 |
Dinarello CA. An Interleukin-1 Signature in Breast Cancer Treated with Interleukin-1 Receptor Blockade: Implications for Treating Cytokine Release Syndrome of Checkpoint Inhibitors. Cancer Research. 78: 5200-5202. PMID 30217872 DOI: 10.1158/0008-5472.Can-18-2225 |
0.528 |
|
| 2018 |
Wade MF, Collins MK, Richards D, Mack DG, Martin AK, Dinarello CA, Fontenot AP, McKee AS. TLR9 and IL-1R1 Promote Mobilization of Pulmonary Dendritic Cells During Beryllium Sensitization. Journal of Immunology (Baltimore, Md. : 1950). PMID 30185516 DOI: 10.4049/Jimmunol.1800303 |
0.578 |
|
| 2018 |
Tengesdal IW, Kitzenberg D, Li S, Nyuydzefe MS, Chen W, Weiss JM, Zhang J, Waksal SD, Zanin-Zhorov A, Dinarello CA. The selective ROCK2 inhibitor KD025 reduces IL-17 secretion in human peripheral blood mononuclear cells independent of IL-1 and IL-6. European Journal of Immunology. PMID 30098001 DOI: 10.1002/Eji.201847652 |
0.698 |
|
| 2018 |
Marchetti C, Swartzwelter B, Koenders MI, Azam T, Tengesdal IW, Powers N, de Graaf DM, Dinarello CA, Joosten LAB. NLRP3 inflammasome inhibitor OLT1177 suppresses joint inflammation in murine models of acute arthritis. Arthritis Research & Therapy. 20: 169. PMID 30075804 DOI: 10.1186/S13075-018-1664-2 |
0.499 |
|
| 2018 |
De Luca G, Campochiaro C, Dinarello CA, Dagna L, Cavalli G. Treatment of Dilated Cardiomyopathy With Interleukin-1 Inhibition. Annals of Internal Medicine. PMID 30073251 DOI: 10.7326/L18-0315 |
0.492 |
|
| 2018 |
Kuipers EN, van Dam AD, Ballak DB, de Wit EA, Dinarello CA, Stienstra R, van Diepen JA, Rensen PCN, Boon MR. IL-37 Expression Reduces Lean Body Mass in Mice by Reducing Food Intake. International Journal of Molecular Sciences. 19. PMID 30072596 DOI: 10.3390/Ijms19082264 |
0.628 |
|
| 2018 |
Ballak DB, Li S, Cavalli G, Stahl JL, Tengesdal IW, van Diepen JA, Kluck V, Swartzwelter B, Azam T, Track CJ, Stienstra R, Mandrup-Poulsen T, Seals DR, Dinarello CA. Interleukin-37 Treatment of Mice with Metabolic Syndrome Improves Insulin Sensitivity and Reduces Pro-inflammatory Cytokine Production in Adipose Tissue. The Journal of Biological Chemistry. PMID 30006351 DOI: 10.1074/Jbc.Ra118.003698 |
0.669 |
|
| 2018 |
Dinarello CA, Kaplanski G. Indeed, IL-18 is more than an inducer of IFN-γ. Journal of Leukocyte Biology. 104: 237-238. PMID 29733453 DOI: 10.1002/Jlb.Ce0118-025Rr |
0.661 |
|
| 2018 |
Damen MSMA, Dos Santos JC, Hermsen R, Adam van der Vliet J, Netea MG, Riksen NP, Dinarello CA, Joosten LAB, Heinhuis B. Interleukin-32 upregulates the expression of ABCA1 and ABCG1 resulting in reduced intracellular lipid concentrations in primary human hepatocytes. Atherosclerosis. 271: 193-202. PMID 29524862 DOI: 10.1016/J.Atherosclerosis.2018.02.027 |
0.628 |
|
| 2018 |
Gomes RS, Silva MVT, Dos Santos JC, van Linge C, Reis JM, Teixeira MM, Pinto SA, Dorta ML, Bai X, Chan ED, Dinarello CA, de Oliveira MAP, Joosten LAB, Ribeiro-Dias F. Human IL-32γ plays a protective role in an experimental model of visceral leishmaniasis in mice. Infection and Immunity. PMID 29483288 DOI: 10.1128/Iai.00796-17 |
0.603 |
|
| 2018 |
Brinkmann CR, Højen JF, Rasmussen TA, Kjær AS, Olesen R, Denton PW, Østergaard L, Ouyang Z, Lichterfeld M, Yu X, Søgaard OS, Dinarello C, Tolstrup M. Treatment of HIV-Infected Individuals with the Histone Deacetylase Inhibitor Panobinostat Results in Increased Numbers of Regulatory T Cells and LimitsLipopolysaccharide-Induced Inflammatory Responses. Msphere. 3. PMID 29468194 DOI: 10.1128/mSphere.00616-17 |
0.414 |
|
| 2018 |
Kerstholt M, Vrijmoeth H, Lachmandas E, Oosting M, Lupse M, Flonta M, Dinarello CA, Netea MG, Joosten LAB. Role of glutathione metabolism in host defense againstinfection. Proceedings of the National Academy of Sciences of the United States of America. 115: E2320-E2328. PMID 29444855 DOI: 10.1073/Pnas.1720833115 |
0.493 |
|
| 2018 |
Magenau JM, Goldstein SC, Peltier D, Soiffer RJ, Braun T, Pawarode A, Riwes MM, Kennel M, Antin JH, Cutler CS, Ho VT, Alyea EP, Parkin BL, Yanik GA, Choi SW, ... ... Dinarello CA, et al. α1-Antitrypsin Infusion for treatment of Steroid Resistant Acute Graft-versus-Host Disease. Blood. PMID 29437593 DOI: 10.1182/Blood-2017-11-815746 |
0.479 |
|
| 2018 |
Jeong MY, Lin YH, Wennersten SA, Demos-Davies KM, Cavasin MA, Mahaffey JH, Monzani V, Saripalli C, Mascagni P, Reece TB, Ambardekar AV, Granzier HL, Dinarello CA, McKinsey TA. Histone deacetylase activity governs diastolic dysfunction through a nongenomic mechanism. Science Translational Medicine. 10. PMID 29437146 DOI: 10.1126/Scitranslmed.Aao0144 |
0.443 |
|
| 2018 |
Marchetti C, Swartzwelter B, Gamboni F, Neff CP, Richter K, Azam T, Carta S, Tengesdal I, Nemkov T, D'Alessandro A, Henry C, Jones GS, Goodrich SA, St Laurent JP, Jones TM, ... ... Dinarello CA, et al. OLT1177, a β-sulfonyl nitrile compound, safe in humans, inhibits the NLRP3 inflammasome and reverses the metabolic cost of inflammation. Proceedings of the National Academy of Sciences of the United States of America. PMID 29378952 DOI: 10.1073/Pnas.1716095115 |
0.612 |
|
| 2018 |
Dinarello CA. Introduction to the interleukin-1 family of cytokines and receptors: Drivers of innate inflammation and acquired immunity. Immunological Reviews. 281: 5-7. PMID 29248001 DOI: 10.1111/Imr.12624 |
0.502 |
|
| 2018 |
Dinarello CA. Overview of the IL-1 family in innate inflammation and acquired immunity. Immunological Reviews. 281: 8-27. PMID 29247995 DOI: 10.1111/Imr.12621 |
0.579 |
|
| 2018 |
Cavalli G, Dinarello CA. Suppression of inflammation and acquired immunity by IL-37. Immunological Reviews. 281: 179-190. PMID 29247987 DOI: 10.1111/Imr.12605 |
0.62 |
|
| 2018 |
van de Veerdonk FL, de Graaf DM, Joosten LA, Dinarello CA. Biology of IL-38 and its role in disease. Immunological Reviews. 281: 191-196. PMID 29247986 DOI: 10.1111/Imr.12612 |
0.592 |
|
| 2018 |
Cavalli G, Deuren Rv, Arts P, Steehouwer M, Gilissen C, Sfriso P, Galozzi P, Colafrancesco S, Priori R, Cantarini L, Lucherini OM, Rodolfi S, Luca GD, Baldissera E, Veerdonk Fvd, ... ... Dinarello CA, et al. OP0285 Identification of rare coding variants in il-1-related pathways in patients with adult-onset still’s disease Annals of the Rheumatic Diseases. 77: 190-190. DOI: 10.1136/Annrheumdis-2018-Ewrr2019.93 |
0.516 |
|
| 2018 |
Graaf DMD, Veerdonk FLVd, Eisenmesser EZ, Joosten LAB, Dinarello CA. OP0170 Human il-38 reduces joint inflammation in a mouse model of gouty arthritis Annals of the Rheumatic Diseases. 77: 135-135. DOI: 10.1136/Annrheumdis-2018-Eular.5599 |
0.58 |
|
| 2018 |
Menghini P, Buttó LF, Dinarello CA, Cominelli F. Tu1767 - Blockade of IL-1α Ameliorates Ileitis and DSS Induced Colitis in Samp1/Yitfc Mice by a Mechanism Involving Direct Modulation of the Gut Microbiome Gastroenterology. 154. DOI: 10.1016/S0016-5085(18)33393-6 |
0.48 |
|
| 2018 |
Rønholt K, Langkilde A, Johansen C, Vales R, Dinarello C, Iversen L. 439 The role of IL-37 in psoriasis Journal of Investigative Dermatology. 138. DOI: 10.1016/J.Jid.2018.03.446 |
0.548 |
|
| 2018 |
Osborne D, Domenico J, Dinarello C, Fujita M. 118 A dual role of IL-37 in adaptive immunity Journal of Investigative Dermatology. 138. DOI: 10.1016/J.Jid.2018.03.122 |
0.491 |
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| 2018 |
Pietras E, Rabe J, Higa K, Chavez J, Mills T, Nemkov T, Nerlov C, Dinarello C, D'Alessandro A, DeGregori J. IL-1 Drives Clonal Hematopoiesis via Selective Induction of Growth Arrest in Normal HSC Experimental Hematology. 64: S93. DOI: 10.1016/J.Exphem.2018.06.119 |
0.481 |
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| 2017 |
Kurzrock R, Hickish T, Wyrwicz L, André T, Sarosiek T, Kocsis J, Nemecek R, Wu Q, Mohanty P, Stecher M, Simard J, Dinarello C. Pre-treatment endogenous interleukin-1 receptor antagonist (IL-1Ra) levels in metastatic colorectal cancer (mCRC) patients are associated with clinical outcomes after anti-interleukin-1a therapy (MABp1). Annals of Oncology : Official Journal of the European Society For Medical Oncology. 28: iii98-iii99. PMID 32136086 DOI: 10.1093/Annonc/Mdx261.280 |
0.413 |
|
| 2017 |
Nold-Petry CA, Nold MF, Levy O, Kliger Y, Oren A, Borukhov I, Becker C, Wirtz S, Sandhu MK, Neurath M, Dinarello CA. Gp96 Peptide Antagonist gp96-II Confers Therapeutic Effects in Murine Intestinal Inflammation. Frontiers in Immunology. 8: 1531. PMID 29312281 DOI: 10.3389/Fimmu.2017.01531 |
0.442 |
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| 2017 |
Grabherr F, Grander C, Adolph TE, Wieser V, Mayr L, Enrich B, Macheiner S, Sangineto M, Reiter A, Viveiros A, Zoller H, Bufler P, Moschen AR, Dinarello CA, Tilg H. Ethanol-mediated suppression of IL-37 licenses alcoholic liver disease. Liver International : Official Journal of the International Association For the Study of the Liver. PMID 29193575 DOI: 10.1111/Liv.13642 |
0.487 |
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| 2017 |
Kanni T, Argyropoulou M, Spyridopoulos T, Pistiki A, Stecher M, Dinarello CA, Simard J, Giamarellos-Bourboulis EJ. MABp1 Targeting IL-1α for Moderate to Severe Hidradenitis Suppurativa Not Eligible for Adalimumab: a Randomized Study. The Journal of Investigative Dermatology. PMID 29129600 DOI: 10.1016/J.Jid.2017.10.030 |
0.578 |
|
| 2017 |
Cavalli G, Koenders M, Kalabokis V, Kim J, Choon Tan A, Garlanda C, Mantovani A, Dagna L, Joosten LAB, Dinarello CA. Treating experimental arthritis with the innate immune inhibitor interleukin-37 reduces joint and systemic inflammation. Rheumatology (Oxford, England). PMID 28968825 DOI: 10.1093/Rheumatology/Kex348 |
0.472 |
|
| 2017 |
Hoeke G, Khedoe PPSJ, van Diepen JA, Pike-Overzet K, van de Ven B, Vazirpanah N, Mol I, Hiemstra PS, Staal FJT, Stienstra R, Netea MG, Dinarello CA, Rensen PCN, Berbée JFP. The Effects of Selective Hematopoietic Expression of Human IL-37 on Systemic Inflammation and Atherosclerosis in LDLr-Deficient Mice. International Journal of Molecular Sciences. 18. PMID 28792474 DOI: 10.3390/Ijms18081672 |
0.597 |
|
| 2017 |
Choi SW, Braun T, Henig I, Gatza E, Magenau J, Parkin B, Pawarode A, Riwes M, Yanik G, Dinarello CA, Reddy P. Vorinostat plus tacrolimus/methotrexate to prevent GVHD following myeloablative conditioning unrelated donor HCT. Blood. PMID 28784598 DOI: 10.1182/Blood-2017-06-790469 |
0.464 |
|
| 2017 |
Netea MG, Balkwill F, Chonchol M, Cominelli F, Donath MY, Giamarellos-Bourboulis EJ, Golenbock D, Gresnigt MS, Heneka MT, Hoffman HM, Hotchkiss R, Joosten LAB, Kastner DL, Korte M, Latz E, ... ... Dinarello CA, et al. A guiding map for inflammation. Nature Immunology. 18: 826-831. PMID 28722720 DOI: 10.1038/Ni.3790 |
0.453 |
|
| 2017 |
Damen MSMA, Popa CD, Netea MG, Dinarello CA, Joosten LAB. Interleukin-32 in chronic inflammatory conditions is associated with a higher risk of cardiovascular diseases. Atherosclerosis. 264: 83-91. PMID 28716457 DOI: 10.1016/J.Atherosclerosis.2017.07.005 |
0.588 |
|
| 2017 |
Gomes RS, Silva MVT, Dos Santos JC, de Lima Silva LL, Batista AC, Machado JR, Teixeira MM, Dorta ML, de Oliveira MAP, Dinarello CA, Joosten LAB, Ribeiro-Dias F. IL-32γ promotes the healing of murine cutaneous lesions caused by Leishmania braziliensis infection in contrast to Leishmania amazonensis. Parasites & Vectors. 10: 336. PMID 28709468 DOI: 10.1186/S13071-017-2268-4 |
0.586 |
|
| 2017 |
Schauer AE, Klassert TE, von Lachner C, Riebold D, Schneeweiß A, Stock M, Müller MM, Hammerschmidt S, Bufler P, Seifert U, Dietert K, Dinarello CA, Nold MF, Gruber AD, Nold-Petry CA, et al. IL-37 Causes Excessive Inflammation and Tissue Damage in Murine Pneumococcal Pneumonia. Journal of Innate Immunity. 9: 403-418. PMID 28601872 DOI: 10.1159/000469661 |
0.613 |
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| 2017 |
Neudecker V, Haneklaus M, Jensen O, Khailova L, Masterson JC, Tye H, Biette K, Jedlicka P, Brodsky KS, Gerich ME, Mack M, Robertson AAB, Cooper MA, Furuta GT, Dinarello CA, et al. Myeloid-derived miR-223 regulates intestinal inflammation via repression of the NLRP3 inflammasome. The Journal of Experimental Medicine. PMID 28487310 DOI: 10.1084/Jem.20160462 |
0.477 |
|
| 2017 |
Crişan TO, Cleophas MCP, Novakovic B, Erler K, van de Veerdonk FL, Stunnenberg HG, Netea MG, Dinarello CA, Joosten LAB. Uric acid priming in human monocytes is driven by the AKT-PRAS40 autophagy pathway. Proceedings of the National Academy of Sciences of the United States of America. 114: 5485-5490. PMID 28484006 DOI: 10.1073/Pnas.1620910114 |
0.561 |
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| 2017 |
Novick D, Dinarello CA. IL-18 binding protein reverses the life-threatening hyperinflammation of a baby with the NLRC4 mutation. The Journal of Allergy and Clinical Immunology. 140: 316. PMID 28457594 DOI: 10.1016/J.Jaci.2017.02.037 |
0.527 |
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| 2017 |
Zhan Q, Zeng Q, Song R, Zhai Y, Xu D, Fullerton DA, Dinarello CA, Meng X. IL-37 suppresses MyD88-mediated inflammatory responses in human aortic valve interstitial cells. Molecular Medicine (Cambridge, Mass.). 23. PMID 28362018 DOI: 10.2119/Molmed.2017.00022 |
0.55 |
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| 2017 |
Needell JC, Dinarello CA, Ir D, Robertson CE, Ryan SM, Kroehl ME, Frank DN, Zipris D. Implication of the intestinal microbiome as a potential surrogate marker of immune responsiveness to experimental therapies in autoimmune diabetes. Plos One. 12: e0173968. PMID 28301545 DOI: 10.1371/Journal.Pone.0173968 |
0.534 |
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| 2017 |
Roerink ME, Bredie SJH, Heijnen M, Dinarello CA, Knoop H, Van der Meer JWM. Cytokine Inhibition in Patients With Chronic Fatigue Syndrome: A Randomized Trial. Annals of Internal Medicine. 166: 557-564. PMID 28265678 DOI: 10.7326/M16-2391 |
0.54 |
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| 2017 |
Zhai Z, Liu W, Kaur M, Luo Y, Domenico J, Samson JM, Shellman YG, Norris DA, Dinarello CA, Spritz RA, Fujita M. NLRP1 promotes tumor growth by enhancing inflammasome activation and suppressing apoptosis in metastatic melanoma. Oncogene. PMID 28263976 DOI: 10.1038/Onc.2017.26 |
0.39 |
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| 2017 |
Dos Santos JC, Heinhuis B, Gomes RS, Damen MS, Real F, Mortara RA, Keating ST, Dinarello CA, Joosten LA, Ribeiro-Dias F. Cytokines and microbicidal molecules regulated by IL-32 in THP-1-derived human macrophages infected with New World Leishmania species. Plos Neglected Tropical Diseases. 11: e0005413. PMID 28241012 DOI: 10.1371/Journal.Pntd.0005413 |
0.594 |
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| 2017 |
Li J, Zhai Y, Ao L, Hui H, Fullerton DA, Dinarello CA, Meng X. Interleukin-37 suppresses the inflammatory response to protect cardiac function in old endotoxemic mice. Cytokine. 95: 55-63. PMID 28237874 DOI: 10.1016/J.Cyto.2017.02.008 |
0.597 |
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| 2017 |
Maicas N, van der Vlag J, Bublitz J, Florquin S, Bakker-van Bebber M, Dinarello CA, Verweij V, Masereeuw R, Joosten LA, Hilbrands LB. Human Alpha-1-Antitrypsin (hAAT) therapy reduces renal dysfunction and acute tubular necrosis in a murine model of bilateral kidney ischemia-reperfusion injury. Plos One. 12: e0168981. PMID 28235038 DOI: 10.1371/Journal.Pone.0168981 |
0.473 |
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| 2017 |
Cavalli G, Foppoli M, Cabrini L, Dinarello CA, Tresoldi M, Dagna L. Interleukin-1 Receptor Blockade Rescues Myocarditis-Associated End-Stage Heart Failure. Frontiers in Immunology. 8: 131. PMID 28232838 DOI: 10.3389/Fimmu.2017.00131 |
0.557 |
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| 2017 |
Davegårdh C, Broholm C, Perfilyev A, Henriksen T, García-Calzón S, Peijs L, Hansen NS, Volkov P, Kjøbsted R, Wojtaszewski JF, Pedersen M, Pedersen BK, Ballak DB, Dinarello CA, Heinhuis B, et al. Abnormal epigenetic changes during differentiation of human skeletal muscle stem cells from obese subjects. Bmc Medicine. 15: 39. PMID 28222718 DOI: 10.1186/S12916-017-0792-X |
0.436 |
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| 2017 |
Cavalli G, Justice JN, Boyle KE, D'Alessandro A, Eisenmesser EZ, Herrera JJ, Hansen KC, Nemkov T, Stienstra R, Garlanda C, Mantovani A, Seals DR, Dagna L, Joosten LA, Ballak DB, ... Dinarello CA, et al. Interleukin 37 reverses the metabolic cost of inflammation, increases oxidative respiration, and improves exercise tolerance. Proceedings of the National Academy of Sciences of the United States of America. PMID 28193888 DOI: 10.1073/Pnas.1619011114 |
0.594 |
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| 2017 |
Rider P, Voronov E, Dinarello CA, Apte RN, Cohen I. Alarmins: Feel the Stress. Journal of Immunology (Baltimore, Md. : 1950). 198: 1395-1402. PMID 28167650 DOI: 10.4049/Jimmunol.1601342 |
0.559 |
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| 2017 |
Zeng Q, Song R, Fullerton DA, Ao L, Zhai Y, Li S, Ballak DB, Cleveland JC, Reece TB, McKinsey TA, Xu D, Dinarello CA, Meng X. Interleukin-37 suppresses the osteogenic responses of human aortic valve interstitial cells in vitro and alleviates valve lesions in mice. Proceedings of the National Academy of Sciences of the United States of America. PMID 28137840 DOI: 10.1073/Pnas.1619667114 |
0.549 |
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| 2017 |
Damen MS, Agca R, Holewijn S, de Graaf J, Dos Santos JC, van Riel PL, Fransen J, Coenen MJ, Nurmohamed MT, Netea MG, Dinarello CA, Joosten LA, Heinhuis B, Popa CD. IL-32 promoter SNP rs4786370 predisposes to modified lipoprotein profiles in patients with rheumatoid arthritis. Scientific Reports. 7: 41629. PMID 28134327 DOI: 10.1038/Srep41629 |
0.526 |
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| 2017 |
Roerink ME, van der Schaaf ME, Dinarello CA, Knoop H, van der Meer JW. Interleukin-1 as a mediator of fatigue in disease: a narrative review. Journal of Neuroinflammation. 14: 16. PMID 28109186 DOI: 10.1186/S12974-017-0796-7 |
0.585 |
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| 2017 |
Davis CJ, Zielinski MR, Dunbrasky D, Taishi P, Dinarello CA, Krueger JM. Interleukin 37 expression in mice alters sleep responses to inflammatory agents and influenza virus infection. Neurobiology of Sleep and Circadian Rhythms. 3: 1-9. PMID 28070566 DOI: 10.1016/J.Nbscr.2016.11.005 |
0.515 |
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| 2017 |
Geffen EV, Caam Av, Beuningen Hv, Vitters E, Dinarello C, Davidson EB, Kraan Pvd. AB0031 Il37 inhibits gag release from human oa cartilage explants Annals of the Rheumatic Diseases. 76: 1057-1058. DOI: 10.1136/Annrheumdis-2017-Eular.3689 |
0.443 |
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| 2017 |
Marchetti C, Swartzwelter B, Koenders M, Dinarello C, Joosten L. OP0090 The human safe NLRP3 inflammasome inhibitor OLT1177 suppresses joint inflammation in murine models of experimental arthritis Annals of the Rheumatic Diseases. 76: 89-89. DOI: 10.1136/Annrheumdis-2017-Eular.2775 |
0.531 |
|
| 2017 |
Cavalli G, Ballak D, Justice J, Boyle K, D'Alessandro A, Joosten L, Dagna L, Dinarello C. OP0092 Interleukin 37 reverses the metabolic cost of inflammation, increases oxidative respiration and improves exercise tolerance Annals of the Rheumatic Diseases. 76: 90-90. DOI: 10.1136/Annrheumdis-2017-Eular.1789 |
0.557 |
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| 2017 |
Menghini P, Corridoni D, Dinarello CA, Aladyshkina N, Choudhury K, Shivaswamy S, Rodriguez-Palacios A, Cominelli F. IL-1α Neutralization Markedly Ameliorates Crohn's Disease (CD)-Like Ileitis by a Mechanism Altering Gut Microbiome Composition Gastroenterology. 152: S89. DOI: 10.1016/S0016-5085(17)30648-0 |
0.427 |
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| 2017 |
Li Y, Okamoto M, Dinarello C, Fujita M. 812 An imbalance between IL-1 and IL-1Ra in human melanoma cells accounts for autoinflammation and contributes to tumor progression in metastatic melanoma Journal of Investigative Dermatology. 137. DOI: 10.1016/J.Jid.2017.02.837 |
0.518 |
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| 2016 |
Arts RJ, Novakovic B, Ter Horst R, Carvalho A, Bekkering S, Lachmandas E, Rodrigues F, Silvestre R, Cheng SC, Wang SY, Habibi E, Gonçalves LG, Mesquita I, Cunha C, van Laarhoven A, ... ... Dinarello CA, et al. Glutaminolysis and Fumarate Accumulation Integrate Immunometabolic and Epigenetic Programs in Trained Immunity. Cell Metabolism. PMID 27866838 DOI: 10.1016/J.Cmet.2016.10.008 |
0.452 |
|
| 2016 |
Ter Horst R, Jaeger M, Smeekens SP, Oosting M, Swertz MA, Li Y, Kumar V, Diavatopoulos DA, Jansen AF, Lemmers H, Toenhake-Dijkstra H, van Herwaarden AE, Janssen M, van der Molen RG, Joosten I, ... ... Dinarello CA, et al. Host and Environmental Factors Influencing Individual Human Cytokine Responses. Cell. 167: 1111-1124.e13. PMID 27814508 DOI: 10.1016/J.Cell.2016.10.018 |
0.534 |
|
| 2016 |
Bekkering S, van den Munckhof I, Nielen T, Lamfers E, Dinarello C, Rutten J, de Graaf J, Joosten LA, Netea MG, Gomes ME, Riksen NP. Innate immune cell activation and epigenetic remodeling in symptomatic and asymptomatic atherosclerosis in humans in vivo. Atherosclerosis. 254: 228-236. PMID 27764724 DOI: 10.1016/J.Atherosclerosis.2016.10.019 |
0.483 |
|
| 2016 |
Nowak KL, Chonchol M, Ikizler TA, Farmer-Bailey H, Salas N, Chaudhry R, Wang W, Smits G, Tengesdal I, Dinarello CA, Hung AM. IL-1 Inhibition and Vascular Function in CKD. Journal of the American Society of Nephrology : Jasn. PMID 27647856 DOI: 10.1681/Asn.2016040453 |
0.501 |
|
| 2016 |
Cavalli G, Koenders M, Kalabokis V, Kim J, Tan AC, Garlanda C, Mantovani A, Dagna L, Joosten LA, Dinarello CA. Treating experimental arthritis with the innate immune inhibitor interleukin-37 reduces joint and systemic inflammation. Rheumatology (Oxford, England). PMID 27567100 DOI: 10.1093/Rheumatology/Kew325 |
0.583 |
|
| 2016 |
Netea MG, Joosten LA, Li Y, Kumar V, Oosting M, Smeekens S, Jaeger M, Ter Horst R, Schirmer M, Vlamakis H, Notebaart R, Pavelka N, Aguirre-Gamboa RR, Swertz MA, Tunjungputri RN, ... ... Dinarello CA, et al. Understanding human immune function using the resources from the Human Functional Genomics Project. Nature Medicine. 22: 831-833. PMID 27490433 DOI: 10.1038/Nm.4140 |
0.472 |
|
| 2016 |
Aggarwal N, Korenbaum E, Mahadeva R, Immenschuh S, Grau V, Dinarello CA, Welte T, Janciauskiene S. α-Linoleic acid enhances the capacity of α-1 antitrypsin to inhibit lipopolysaccharide-induced IL-1β in human blood neutrophils. Molecular Medicine (Cambridge, Mass.). 22. PMID 27452044 DOI: 10.2119/Molmed.2016.00119 |
0.59 |
|
| 2016 |
Toonen EJ, Mirea AM, Tack CJ, Stienstra R, Ballak DB, van Diepen JA, Hijmans A, Chavakis T, Dokter WH, Pham CT, Netea MG, Dinarello CA, Joosten LA. Activation of proteinase 3 contributes to Non-alcoholic Fatty Liver Disease (NAFLD) and insulin resistance. Molecular Medicine (Cambridge, Mass.). 22. PMID 27261776 DOI: 10.2119/Molmed.2016.00033 |
0.488 |
|
| 2016 |
Marcondes AM, Hockenbery D, Lesnikova M, Dinarello CA, Woolfrey A, Gernsheimer T, Loghman-Adham M, Gelmont D, Storer B, Hansen JA, Deeg HJ. Response of Steroid-Refractory Acute GVHD to α1-Anti-Trypsin. Biology of Blood and Marrow Transplantation : Journal of the American Society For Blood and Marrow Transplantation. PMID 27223109 DOI: 10.1016/J.Bbmt.2016.05.011 |
0.488 |
|
| 2016 |
Joosten LA, Abdollahi-Roodsaz S, Dinarello CA, O'Neill L, Netea MG. Toll-like receptors and chronic inflammation in rheumatic diseases: new developments. Nature Reviews. Rheumatology. 12: 344-57. PMID 27170508 DOI: 10.1038/Nrrheum.2016.61 |
0.496 |
|
| 2016 |
Dinarello CA, Nold-Petry C, Nold M, Fujita M, Li S, Kim S, Bufler P. Suppression of innate inflammation and immunity by interleukin-37. European Journal of Immunology. PMID 27060871 DOI: 10.1002/Eji.201545828 |
0.605 |
|
| 2016 |
Cavalli G, Pappalardo F, Mangieri A, Dinarello CA, Dagna L, Tresoldi M. Treating Life-Threatening Myocarditis by Blocking Interleukin-1. Critical Care Medicine. 44: e751-4. PMID 27031379 DOI: 10.1097/Ccm.0000000000001654 |
0.511 |
|
| 2016 |
Iannitti RG, Napolioni V, Oikonomou V, De Luca A, Galosi C, Pariano M, Massi-Benedetti C, Borghi M, Puccetti M, Lucidi V, Colombo C, Fiscarelli E, Lass-Flörl C, Majo F, Cariani L, ... ... Dinarello CA, et al. IL-1 receptor antagonist ameliorates inflammasome-dependent inflammation in murine and human cystic fibrosis. Nature Communications. 7: 10791. PMID 26972847 DOI: 10.1038/Ncomms10791 |
0.644 |
|
| 2016 |
Lust JA, Lacy MQ, Zeldenrust SR, Witzig TE, Moon-Tasson LL, Dinarello CA, Donovan KA. Reduction in C-reactive protein indicates successful targeting of the IL-1/IL-6 axis resulting in improved survival in early stage multiple myeloma. American Journal of Hematology. PMID 26945843 DOI: 10.1002/Ajh.24352 |
0.608 |
|
| 2016 |
Toldo S, Mauro AG, Marchetti C, Rose SW, Mezzaroma E, Van Tassell BW, Kim S, Dinarello CA, Abbate A. Recombinant Human Alpha-1 Anti-Trypsin-Fc Fusion Protein Reduces Mouse Myocardial Inflammatory Injury Following Ischemia Reperfusion Independent Of Elastase Inhibition. Journal of Cardiovascular Pharmacology. PMID 26945157 DOI: 10.1097/Fjc.0000000000000383 |
0.483 |
|
| 2016 |
Van Tassell BW, Abouzaki NA, Erdle CO, Carbone S, Trankle C, Melchior RD, Turlington JS, Thurber C, Christopher S, Dixon DL, Fronk DT, Thomas CS, Rose SW, Buckley LF, Dinarello CA, et al. Interleukin-1 Blockade In Acute Decompensated Heart Failure: A Randomized, Double-Blinded, Placebo-Controlled Pilot Study. Journal of Cardiovascular Pharmacology. PMID 26906034 DOI: 10.1097/Fjc.0000000000000378 |
0.497 |
|
| 2016 |
Shirey KA, Lai W, Patel MC, Pletneva LM, Pang C, Kurt-Jones E, Lipsky M, Roger T, Calandra T, Tracey KJ, Al-Abed Y, Bowie AG, Fasano A, Dinarello CA, Gusovsky F, et al. Novel strategies for targeting innate immune responses to influenza. Mucosal Immunology. PMID 26813341 DOI: 10.1038/Mi.2015.141 |
0.409 |
|
| 2016 |
Cavalli G, Hayashi M, Jin Y, Yorgov D, Santorico SA, Holcomb C, Rastrou M, Erlich H, Tengesdal IW, Dagna L, Neff CP, Palmer BE, Spritz RA, Dinarello CA. MHC class II super-enhancer increases surface expression of HLA-DR and HLA-DQ and affects cytokine production in autoimmune vitiligo. Proceedings of the National Academy of Sciences of the United States of America. PMID 26787888 DOI: 10.1073/Pnas.1523482113 |
0.498 |
|
| 2016 |
Hayashi M, Jin Y, Yorgov D, Santorico SA, Hagman J, Ferrara TM, Jones KL, Cavalli G, Dinarello CA, Spritz RA. Autoimmune vitiligo is associated with gain-of-function by a transcriptional regulator that elevates expression of HLA-A*02:01 in vivo. Proceedings of the National Academy of Sciences of the United States of America. PMID 26787886 DOI: 10.1073/Pnas.1525001113 |
0.443 |
|
| 2016 |
Coll-Miró M, Francos-Quijorna I, Santos-Nogueira E, Torres-Espin A, Bufler P, Dinarello CA, López-Vales R. Beneficial effects of IL-37 after spinal cord injury in mice. Proceedings of the National Academy of Sciences of the United States of America. PMID 26787859 DOI: 10.1073/Pnas.1523212113 |
0.628 |
|
| 2016 |
Dinarello CA, Joosten LA. Inflammation in rheumatology in 2015: New tools to tackle inflammatory arthritis. Nature Reviews. Rheumatology. 12: 78-80. PMID 26763730 DOI: 10.1038/Nrrheum.2015.180 |
0.558 |
|
| 2016 |
Cohen I, Rider P, Vornov E, Tomas M, Tudor C, Wegner M, Brondani L, Freudenberg M, Mittler G, Ferrando-May E, Dinarello CA, Apte RN, Schneider R. Corrigendum: IL-1α is a DNA damage sensor linking genotoxic stress signaling to sterile inflammation and innate immunity. Scientific Reports. 6: 19100. PMID 26750721 DOI: 10.1038/Srep19100 |
0.622 |
|
| 2016 |
Højen JF, Taylor MK, Azam T, Fischer S, Pollyea DA, Jordan CT, Dinarello CA. Development of Anti-IL-1R3 Monoclonal Antibodies for Treating Cancer and IL-1 Family-Mediated Inflammation Blood. 128: 5224-5224. DOI: 10.1182/Blood.V128.22.5224.5224 |
0.559 |
|
| 2016 |
Cavalli G, Koenders M, Kim J, Tan A, Garlanda C, Mantovani A, Dagna L, Joosten L, Dinarello C. FRI0001 Treating Experimental Arthritis with The Innate Immune Inhibitor IL-37 Reduces Joint and Systemic Inflammation Annals of the Rheumatic Diseases. 75: 426.1-426. DOI: 10.1136/Annrheumdis-2016-Eular.2713 |
0.571 |
|
| 2016 |
Koenders M, Cavelli G, Joosten L, Kraan Pvd, Berg Wvd, Dinarello C. A7.04 IL-37: Therapeutic potential of a natural inhibitor of innate immunity during acute and chronic experimental arthritis Annals of the Rheumatic Diseases. 75. DOI: 10.1136/Annrheumdis-2016-209124.135 |
0.574 |
|
| 2016 |
Iannitti RG, Napolioni V, Oikonomou V, De Luca A, Galosi C, Pariano M, Massi-Benedetti C, Borghi M, Puccetti M, Lucidi V, Colombo C, Fiscarelli E, Lass-Flörl C, Majo F, Cariani L, ... ... Dinarello CA, et al. IL-1 receptor antagonist ameliorates inflammasome-dependent inflammation in murine and human cystic fibrosis Nature Communications. 7. DOI: 10.1038/ncomms10791 |
0.409 |
|
| 2015 |
Dinarello CA. The history of fever, leukocytic pyrogen and interleukin-1. Temperature (Austin, Tex.). 2: 8-16. PMID 27226996 DOI: 10.1080/23328940.2015.1017086 |
0.592 |
|
| 2015 |
Heinhuis B, Plantinga TS, Semango G, Küsters B, Netea MG, Dinarello CA, Smit JW, Netea-Maier RT, Joosten LA. Alternatively spliced isoforms of IL-32 differentially influence cell death pathways in cancer cell lines. Carcinogenesis. PMID 26678222 DOI: 10.1093/Carcin/Bgv172 |
0.683 |
|
| 2015 |
Shakoory B, Carcillo JA, Chatham WW, Amdur RL, Zhao H, Dinarello CA, Cron RQ, Opal SM. Interleukin-1 Receptor Blockade Is Associated With Reduced Mortality in Sepsis Patients With Features of Macrophage Activation Syndrome: Reanalysis of a Prior Phase III Trial. Critical Care Medicine. PMID 26584195 DOI: 10.1097/Ccm.0000000000001402 |
0.492 |
|
| 2015 |
Tzanetakou V, Kanni T, Giatrakou S, Katoulis A, Papadavid E, Netea MG, Dinarello CA, van der Meer JW, Rigopoulos D, Giamarellos-Bourboulis EJ. Safety and Efficacy of Anakinra in Severe Hidradenitis Suppurativa: A Randomized Clinical Trial. Jama Dermatology. 1-9. PMID 26579854 DOI: 10.1001/Jamadermatol.2015.3903 |
0.491 |
|
| 2015 |
Henry CJ, Casás-Selves M, Kim J, Zaberezhnyy V, Aghili L, Daniel AE, Jimenez L, Azam T, McNamee EN, Clambey ET, Klawitter J, Serkova NJ, Tan AC, Dinarello CA, DeGregori J. Aging-associated inflammation promotes selection for adaptive oncogenic events in B cell progenitors. The Journal of Clinical Investigation. PMID 26551682 DOI: 10.1172/Jci83024 |
0.49 |
|
| 2015 |
Idan C, Peleg R, Elena V, Martin T, Cicerone T, Mareike W, Lydia B, Marina F, Gerhard M, Elisa FM, Dinarello CA, Ron AN, Robert S. IL-1α is a DNA damage sensor linking genotoxic stress signaling to sterile inflammation and innate immunity. Scientific Reports. 5: 14756. PMID 26439902 DOI: 10.1038/Srep14756 |
0.622 |
|
| 2015 |
Roerink ME, Knoop H, Bredie SJ, Heijnen M, Joosten LA, Netea MG, Dinarello CA, van der Meer JW. Cytokine inhibition in chronic fatigue syndrome patients: study protocol for a randomized controlled trial. Trials. 16: 439. PMID 26438161 DOI: 10.1186/S13063-015-0971-Z |
0.55 |
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| 2015 |
Frenzel E, Wrenger S, Brügger B, Salipalli S, Immenschuh S, Aggarwal N, Lichtinghagen R, Mahadeva R, Marcondes AM, Dinarello CA, Welte T, Janciauskiene S. α1-Antitrypsin Combines with Plasma Fatty Acids and Induces Angiopoietin-like Protein 4 Expression. Journal of Immunology (Baltimore, Md. : 1950). 195: 3605-16. PMID 26363050 DOI: 10.4049/Jimmunol.1500740 |
0.493 |
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| 2015 |
Borghi M, De Luca A, Puccetti M, Jaeger M, Mencacci A, Oikonomou V, Pariano M, Garlanda C, Moretti S, Bartoli A, Sobel J, van de Veerdonk FL, Dinarello CA, Netea MG, Romani L. Pathogenic NLRP3 Inflammasome Activity during Candida Infection Is Negatively Regulated by IL-22 via Activation of NLRC4 and IL-1Ra. Cell Host & Microbe. 18: 198-209. PMID 26269955 DOI: 10.1016/J.Chom.2015.07.004 |
0.676 |
|
| 2015 |
Cavalli G, Dinarello CA. Treating rheumatological diseases and co-morbidities with interleukin-1 blocking therapies. Rheumatology (Oxford, England). PMID 26209330 DOI: 10.1093/Rheumatology/Kev269 |
0.687 |
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| 2015 |
Ballak DB, Stienstra R, Tack CJ, Dinarello CA, van Diepen JA. IL-1 family members in the pathogenesis and treatment of metabolic disease: Focus on adipose tissue inflammation and insulin resistance. Cytokine. 75: 280-90. PMID 26194067 DOI: 10.1016/J.Cyto.2015.05.005 |
0.602 |
|
| 2015 |
Joosten LA, Crişan TO, Azam T, Cleophas MC, Koenders MI, van de Veerdonk FL, Netea MG, Kim S, Dinarello CA. Alpha-1-anti-trypsin-Fc fusion protein ameliorates gouty arthritis by reducing release and extracellular processing of IL-1β and by the induction of endogenous IL-1Ra. Annals of the Rheumatic Diseases. PMID 26174021 DOI: 10.1136/Annrheumdis-2014-206966 |
0.65 |
|
| 2015 |
Rider P, Carmi Y, Yossef R, Guttman O, Eini H, Azam T, Dinarello CA, Lewis EC. IL-1 Receptor Antagonist Chimeric Protein: Context-Specific and Inflammation-Restricted Activation. Journal of Immunology (Baltimore, Md. : 1950). 195: 1705-12. PMID 26157171 DOI: 10.4049/Jimmunol.1501168 |
0.679 |
|
| 2015 |
Bai X, Dinarello CA, Chan ED. The role of interleukin-32 against tuberculosis. Cytokine. 76: 585-7. PMID 26144292 DOI: 10.1016/J.Cyto.2015.06.013 |
0.636 |
|
| 2015 |
Bai X, Kinney WH, Su WL, Bai A, Ovrutsky AR, Honda JR, Netea MG, Henao-Tamayo M, Ordway DJ, Dinarello CA, Chan ED. Caspase-3-independent apoptotic pathways contribute to interleukin-32γ-mediated control of Mycobacterium tuberculosis infection in THP-1 cells. Bmc Microbiology. 15: 39. PMID 25887904 DOI: 10.1186/S12866-015-0366-Z |
0.637 |
|
| 2015 |
Højen JF, Rasmussen TA, Andersen KL, Winckelmann AA, Laursen RR, Gunst JD, Møller HJ, Fujita M, Østergaard L, Søgaard OS, Dinarello CA, Tolstrup M. Interleukin-37 Expression Is Increased in Chronic HIV-1-Infected Individuals and Is Associated with Inflammation and the Size of the Total Viral Reservoir. Molecular Medicine (Cambridge, Mass.). 21: 337-45. PMID 25879630 DOI: 10.2119/Molmed.2015.00031 |
0.623 |
|
| 2015 |
Michels M, de Mast Q, Netea MG, Joosten LA, Dinarello CA, Rudiman PI, Sinarta S, Wisaksana R, Alisjahbana B, van der Ven AJ. Normal free interleukin-18 (IL-18) plasma levels in dengue virus infection and the need to measure both total IL-18 and IL-18 binding protein levels. Clinical and Vaccine Immunology : Cvi. 22: 650-5. PMID 25878254 DOI: 10.1128/Cvi.00147-15 |
0.689 |
|
| 2015 |
Kjær ASHK, Brinkmann CR, Dinarello CA, Olesen R, Ostergaard L, Søgaard OS, Tolstrup M, Rasmussen TA. The histone deacetylase inhibitor panobinostat lowers biomarkers of cardiovascular risk and inflammation in HIV patients Aids. 29: 1195-1200. PMID 25870990 DOI: 10.1097/Qad.0000000000000678 |
0.49 |
|
| 2015 |
Bai X, Shang S, Henao-Tamayo M, Basaraba RJ, Ovrutsky AR, Matsuda JL, Takeda K, Chan MM, Dakhama A, Kinney WH, Trostel J, Bai A, Honda JR, Achcar R, Hartney J, ... ... Dinarello CA, et al. Human IL-32 expression protects mice against a hypervirulent strain of Mycobacterium tuberculosis. Proceedings of the National Academy of Sciences of the United States of America. 112: 5111-6. PMID 25820174 DOI: 10.1073/Pnas.1424302112 |
0.669 |
|
| 2015 |
Heneka MT, Carson MJ, El Khoury J, Landreth GE, Brosseron F, Feinstein DL, Jacobs AH, Wyss-Coray T, Vitorica J, Ransohoff RM, Herrup K, Frautschy SA, Finsen B, Brown GC, Verkhratsky A, ... ... Dinarello CA, et al. Neuroinflammation in Alzheimer's disease. The Lancet. Neurology. 14: 388-405. PMID 25792098 DOI: 10.1016/S1474-4422(15)70016-5 |
0.475 |
|
| 2015 |
Carta S, Penco F, Lavieri R, Martini A, Dinarello CA, Gattorno M, Rubartelli A. Cell stress increases ATP release in NLRP3 inflammasome-mediated autoinflammatory diseases, resulting in cytokine imbalance. Proceedings of the National Academy of Sciences of the United States of America. 112: 2835-40. PMID 25730877 DOI: 10.1073/Pnas.1424741112 |
0.681 |
|
| 2015 |
Nold-Petry CA, Lo CY, Rudloff I, Elgass KD, Li S, Gantier MP, Lotz-Havla AS, Gersting SW, Cho SX, Lao JC, Ellisdon AM, Rotter B, Azam T, Mangan NE, Rossello FJ, ... ... Dinarello CA, et al. IL-37 requires the receptors IL-18Rα and IL-1R8 (SIGIRR) to carry out its multifaceted anti-inflammatory program upon innate signal transduction. Nature Immunology. 16: 354-65. PMID 25729923 DOI: 10.1038/Ni.3103 |
0.682 |
|
| 2015 |
Stoffels M, Zaal R, Kok N, van der Meer JW, Dinarello CA, Simon A. ATP-Induced IL-1β Specific Secretion: True Under Stringent Conditions. Frontiers in Immunology. 6: 54. PMID 25729382 DOI: 10.3389/Fimmu.2015.00054 |
0.665 |
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| 2015 |
Cavalli G, Fallanca F, Dinarello CA, Dagna L. Treating pulmonary silicosis by blocking interleukin 1. American Journal of Respiratory and Critical Care Medicine. 191: 596-8. PMID 25723826 DOI: 10.1164/Rccm.201412-2150Le |
0.477 |
|
| 2015 |
Tunjungputri RN, van der Ven AJ, Riksen N, Rongen G, Tacke S, van den Berg TN, Fijnheer R, Gomes ME, Dinarello CA, van de Veerdonk FL, Gasem M, Netea MG, Joosten LA, De Groot PG, de Mast Q. Differential effects of platelets and platelet inhibition by ticagrelor on TLR2- and TLR4-mediated inflammatory responses. Thrombosis and Haemostasis. 113: 1035-45. PMID 25716539 DOI: 10.1160/TH14-07-0579 |
0.441 |
|
| 2015 |
Li S, Neff CP, Barber K, Hong J, Luo Y, Azam T, Palmer BE, Fujita M, Garlanda C, Mantovani A, Kim S, Dinarello CA. Extracellular forms of IL-37 inhibit innate inflammation in vitro and in vivo but require the IL-1 family decoy receptor IL-1R8. Proceedings of the National Academy of Sciences of the United States of America. 112: 2497-502. PMID 25654981 DOI: 10.1073/Pnas.1424626112 |
0.696 |
|
| 2015 |
Cleophas MC, Cri?an TO, Lemmers H, Toenhake-Dijkstra H, Fossati G, Jansen TL, Dinarello CA, Netea MG, Joosten LA. Suppression of monosodium urate crystal-induced cytokine production by butyrate is mediated by the inhibition of class I histone deacetylases. Annals of the Rheumatic Diseases. PMID 25589513 DOI: 10.1136/Annrheumdis-2014-206258 |
0.648 |
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| 2015 |
Ballak DB, van Diepen JA, Moschen AR, Jansen HJ, Hijmans A, Groenhof GJ, Leenders F, Bufler P, Boekschoten MV, Müller M, Kersten S, Li S, Kim S, Eini H, Lewis EC, ... ... Dinarello CA, et al. Corrigendum: IL-37 protects against obesity-induced inflammation and insulin resistance. Nature Communications. 6: 6039. PMID 25580956 DOI: 10.1038/Ncomms7039 |
0.515 |
|
| 2015 |
Netea MG, van de Veerdonk FL, van der Meer JW, Dinarello CA, Joosten LA. Inflammasome-independent regulation of IL-1-family cytokines. Annual Review of Immunology. 33: 49-77. PMID 25493334 DOI: 10.1146/Annurev-Immunol-032414-112306 |
0.693 |
|
| 2015 |
Abbate A, Kontos MC, Abouzaki NA, Melchior RD, Thomas C, Van Tassell BW, Oddi C, Carbone S, Trankle CR, Roberts CS, Mueller GH, Gambill ML, Christopher S, Markley R, Vetrovec GW, ... Dinarello CA, et al. Comparative safety of interleukin-1 blockade with anakinra in patients with ST-segment elevation acute myocardial infarction (from the VCU-ART and VCU-ART2 pilot studies). The American Journal of Cardiology. 115: 288-92. PMID 25482680 DOI: 10.1016/J.Amjcard.2014.11.003 |
0.528 |
|
| 2015 |
Smeekens SP, Gresnigt MS, Becker KL, Cheng SC, Netea SA, Jacobs L, Jansen T, van de Veerdonk FL, Williams DL, Joosten LA, Dinarello CA, Netea MG. An anti-inflammatory property of Candida albicans β-glucan: Induction of high levels of interleukin-1 receptor antagonist via a Dectin-1/CR3 independent mechanism. Cytokine. 71: 215-22. PMID 25461401 DOI: 10.1016/J.Cyto.2014.10.013 |
0.679 |
|
| 2015 |
Abbate A, Van Tassell BW, Christopher S, Abouzaki NA, Sonnino C, Oddi C, Carbone S, Melchior RD, Gambill ML, Roberts CS, Kontos MC, Peberdy MA, Toldo S, Vetrovec GW, Biondi-Zoccai G, ... Dinarello CA, et al. Effects of Prolastin C (Plasma-Derived Alpha-1 Antitrypsin) on the acute inflammatory response in patients with ST-segment elevation myocardial infarction (from the VCU-alpha 1-RT pilot study). The American Journal of Cardiology. 115: 8-12. PMID 25456867 DOI: 10.1016/J.Amjcard.2014.09.043 |
0.481 |
|
| 2015 |
Li S, Fossati G, Marchetti C, Modena D, Pozzi P, Reznikov LL, Moras ML, Azam T, Abbate A, Mascagni P, Dinarello CA. Specific inhibition of histone deacetylase 8 reduces gene expression and production of proinflammatory cytokines in vitro and in vivo. The Journal of Biological Chemistry. 290: 2368-78. PMID 25451941 DOI: 10.1074/Jbc.M114.618454 |
0.682 |
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| 2015 |
Bamias G, Dinarello CA, Rivera-Nieves J. Innate cytokines dictate the fate of acute intestinal inflammation. Gastroenterology. 148: 248-50. PMID 25451656 DOI: 10.1053/J.Gastro.2014.11.013 |
0.685 |
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| 2015 |
Choi SW, Gatza E, Hou G, Sun Y, Whitfield J, Song Y, Oravecz-Wilson K, Tawara I, Dinarello CA, Reddy P. Histone deacetylase inhibition regulates inflammation and enhances Tregs after allogeneic hematopoietic cell transplantation in humans. Blood. 125: 815-9. PMID 25428224 DOI: 10.1182/Blood-2014-10-605238 |
0.507 |
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| 2015 |
Abbate A, Dinarello CA. Anti-inflammatory therapies in acute coronary syndromes: is IL-1 blockade a solution? European Heart Journal. 36: 337-9. PMID 25205529 DOI: 10.1093/Eurheartj/Ehu369 |
0.509 |
|
| 2015 |
Michels M, De Mast Q, Netea MG, Joosten LA, Dinarello CA, Rudiman PIF, Sinarta S, Wisaksana R, Alisjahbana B, Van Der Ven AJAM. Normal free interleukin-18 (IL-18) plasma levels in dengue virus infection and the need to measure both total IL-18 and IL-18 binding protein levels Clinical and Vaccine Immunology. 22: 650-655. DOI: 10.1128/CVI.00147-15 |
0.432 |
|
| 2015 |
Cantarini L, Vitale A, Scalini P, Dinarello CA, Rigante D, Franceschini R, Simonini G, Borsari G, Caso F, Lucherini OM, Frediani B, Bertoldi I, Punzi L, Galeazzi M, Cimaz R. Anakinra treatment in drug-resistant Behcet’s disease: a case series Clinical Rheumatology. 34: 1293-1301. DOI: 10.1007/S10067-013-2443-8 |
0.327 |
|
| 2014 |
Rasmussen TA, Tolstrup M, Brinkmann CR, Olesen R, Erikstrup C, Solomon A, Winckelmann A, Palmer S, Dinarello C, Buzon M, Lichterfeld M, Lewin SR, Østergaard L, Søgaard OS. Panobinostat, a histone deacetylase inhibitor, for latent-virus reactivation in HIV-infected patients on suppressive antiretroviral therapy: a phase 1/2, single group, clinical trial. The Lancet. Hiv. 1: e13-21. PMID 26423811 DOI: 10.1016/S2352-3018(14)70014-1 |
0.434 |
|
| 2014 |
van de Veerdonk FL, Gresnigt MS, Oosting M, van der Meer JW, Joosten LA, Netea MG, Dinarello CA. Protective host defense against disseminated candidiasis is impaired in mice expressing human interleukin-37. Frontiers in Microbiology. 5: 762. PMID 25620965 DOI: 10.3389/Fmicb.2014.00762 |
0.635 |
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| 2014 |
Dinarello CA. An expanding role for interleukin-1 blockade from gout to cancer. Molecular Medicine (Cambridge, Mass.). 20: S43-58. PMID 25549233 DOI: 10.2119/Molmed.2014.00232 |
0.688 |
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| 2014 |
Moretti S, Bozza S, Oikonomou V, Renga G, Casagrande A, Iannitti RG, Puccetti M, Garlanda C, Kim S, Li S, van de Veerdonk FL, Dinarello CA, Romani L. IL-37 inhibits inflammasome activation and disease severity in murine aspergillosis. Plos Pathogens. 10: e1004462. PMID 25375146 DOI: 10.1371/Journal.Ppat.1004462 |
0.693 |
|
| 2014 |
Luo Y, Cai X, Liu S, Wang S, Nold-Petry CA, Nold MF, Bufler P, Norris D, Dinarello CA, Fujita M. Suppression of antigen-specific adaptive immunity by IL-37 via induction of tolerogenic dendritic cells. Proceedings of the National Academy of Sciences of the United States of America. 111: 15178-83. PMID 25294929 DOI: 10.1073/Pnas.1416714111 |
0.658 |
|
| 2014 |
Marcondes AM, Karoopongse E, Lesnikova M, Margineantu D, Welte T, Dinarello CA, Hockenbery D, Janciauskiene S, Deeg HJ. α-1-Antitrypsin (AAT)-modified donor cells suppress GVHD but enhance the GVL effect: a role for mitochondrial bioenergetics. Blood. 124: 2881-91. PMID 25224412 DOI: 10.1182/Blood-2014-04-570440 |
0.466 |
|
| 2014 |
Ballak DB, van Diepen JA, Moschen AR, Jansen HJ, Hijmans A, Groenhof GJ, Leenders F, Bufler P, Boekschoten MV, Müller M, Kersten S, Li S, Kim S, Eini H, Lewis EC, ... ... Dinarello CA, et al. IL-37 protects against obesity-induced inflammation and insulin resistance. Nature Communications. 5: 4711. PMID 25182023 DOI: 10.1038/Ncomms5711 |
0.633 |
|
| 2014 |
Sonnino C, Christopher S, Oddi C, Toldo S, Falcao RA, Melchior RD, Mueller GH, Abouzaki NA, Varma A, Gambill ML, Van Tassell BW, Dinarello CA, Abbate A. Leukocyte activity in patients with ST-segment elevation acute myocardial infarction treated with anakinra. Molecular Medicine (Cambridge, Mass.). 20: 486-9. PMID 25121719 DOI: 10.2119/Molmed.2014.00121 |
0.625 |
|
| 2014 |
van de Veerdonk FL, Dinarello CA. Deficient autophagy unravels the ROS paradox in chronic granulomatous disease. Autophagy. 10: 1141-2. PMID 24879159 DOI: 10.4161/Auto.28638 |
0.624 |
|
| 2014 |
Frenzel E, Wrenger S, Immenschuh S, Koczulla R, Mahadeva R, Deeg HJ, Dinarello CA, Welte T, Marcondes AM, Janciauskiene S. Acute-phase protein α1-antitrypsin--a novel regulator of angiopoietin-like protein 4 transcription and secretion. Journal of Immunology (Baltimore, Md. : 1950). 192: 5354-62. PMID 24760148 DOI: 10.4049/Jimmunol.1400378 |
0.501 |
|
| 2014 |
Dinarello CA. Interleukin-1α neutralisation in patients with cancer. Lancet Oncology. 15: 552-553. PMID 24746840 DOI: 10.1016/S1470-2045(14)70164-0 |
0.472 |
|
| 2014 |
Canada JM, Van Tassell BW, Christopher S, Oddi C, Abouzaki NA, Gambill ML, Mueller G, Melchior R, Shah KB, Dinarello CA, Abbate A, Arena R. Clinical predictors of response to anakinra in patients with heart failure. International Journal of Cardiology. 173: 537-9. PMID 24679681 DOI: 10.1016/J.Ijcard.2014.03.023 |
0.473 |
|
| 2014 |
Gresnigt MS, Bozza S, Becker KL, Joosten LA, Abdollahi-Roodsaz S, van der Berg WB, Dinarello CA, Netea MG, Fontaine T, De Luca A, Moretti S, Romani L, Latge JP, van de Veerdonk FL. A polysaccharide virulence factor from Aspergillus fumigatus elicits anti-inflammatory effects through induction of Interleukin-1 receptor antagonist. Plos Pathogens. 10: e1003936. PMID 24603878 DOI: 10.1371/Journal.Ppat.1003936 |
0.667 |
|
| 2014 |
de Luca A, Smeekens SP, Casagrande A, Iannitti R, Conway KL, Gresnigt MS, Begun J, Plantinga TS, Joosten LA, van der Meer JW, Chamilos G, Netea MG, Xavier RJ, Dinarello CA, Romani L, et al. IL-1 receptor blockade restores autophagy and reduces inflammation in chronic granulomatous disease in mice and in humans. Proceedings of the National Academy of Sciences of the United States of America. 111: 3526-31. PMID 24550444 DOI: 10.1073/Pnas.1322831111 |
0.643 |
|
| 2014 |
Toldo S, Mezzaroma E, O'Brien L, Marchetti C, Seropian IM, Voelkel NF, Van Tassell BW, Dinarello CA, Abbate A. Interleukin-18 mediates interleukin-1-induced cardiac dysfunction. American Journal of Physiology. Heart and Circulatory Physiology. 306: H1025-31. PMID 24531812 DOI: 10.1152/Ajpheart.00795.2013 |
0.688 |
|
| 2014 |
Gottlieb PA, Alkanani AK, Michels AW, Lewis EC, Shapiro L, Dinarello CA, Zipris D. α1-Antitrypsin therapy downregulates toll-like receptor-induced IL-1β responses in monocytes and myeloid dendritic cells and may improve islet function in recently diagnosed patients with type 1 diabetes. The Journal of Clinical Endocrinology and Metabolism. 99: E1418-26. PMID 24527714 DOI: 10.1210/Jc.2013-3864 |
0.56 |
|
| 2014 |
Bulau AM, Nold MF, Li S, Nold-Petry CA, Fink M, Mansell A, Schwerd T, Hong J, Rubartelli A, Dinarello CA, Bufler P. Role of caspase-1 in nuclear translocation of IL-37, release of the cytokine, and IL-37 inhibition of innate immune responses. Proceedings of the National Academy of Sciences of the United States of America. 111: 2650-5. PMID 24481253 DOI: 10.1073/Pnas.1324140111 |
0.698 |
|
| 2014 |
Falcao RA, Christopher S, Oddi C, Reznikov L, Grizzard JD, Abouzaki NA, Varma A, Van Tassell BW, Dinarello CA, Abbate A. Interleukin-10 in patients with ST-segment elevation myocardial infarction. International Journal of Cardiology. 172: e6-8. PMID 24467979 DOI: 10.1016/J.Ijcard.2013.12.126 |
0.447 |
|
| 2014 |
van der Meer JW, Simon A, Dinarello CA. Comment on "Power of rare diseases: found in translation". Science Translational Medicine. 6: 219le1. PMID 24431110 DOI: 10.1126/Scitranslmed.3007911 |
0.439 |
|
| 2014 |
Abbate A, Canada JM, Van Tassell BW, Wise CM, Dinarello CA. Interleukin-1 blockade in rheumatoid arthritis and heart failure: a missed opportunity? International Journal of Cardiology. 171: e125-6. PMID 24418290 DOI: 10.1016/J.Ijcard.2013.12.078 |
0.425 |
|
| 2014 |
Christensen DP, Gysemans C, Lundh M, Dahllöf MS, Noesgaard D, Schmidt SF, Mandrup S, Birkbak N, Workman CT, Piemonti L, Blaabjerg L, Monzani V, Fossati G, Mascagni P, Paraskevas S, ... ... Dinarello CA, et al. Lysine deacetylase inhibition prevents diabetes by chromatin-independent immunoregulation and β-cell protection. Proceedings of the National Academy of Sciences of the United States of America. 111: 1055-9. PMID 24395784 DOI: 10.1073/Pnas.1320850111 |
0.579 |
|
| 2014 |
Nold-Petry CA, Rudloff I, Baumer Y, Ruvo M, Marasco D, Botti P, Farkas L, Cho SX, Zepp JA, Azam T, Dinkel H, Palmer BE, Boisvert WA, Cool CD, Taraseviciene-Stewart L, ... ... Dinarello CA, et al. IL-32 promotes angiogenesis. Journal of Immunology (Baltimore, Md. : 1950). 192: 589-602. PMID 24337385 DOI: 10.4049/Jimmunol.1202802 |
0.685 |
|
| 2014 |
Choi SW, Braun T, Chang L, Ferrara JL, Pawarode A, Magenau JM, Hou G, Beumer JH, Levine JE, Goldstein S, Couriel DR, Stockerl-Goldstein K, Krijanovski OI, Kitko C, Yanik GA, ... ... Dinarello CA, et al. Vorinostat plus tacrolimus and mycophenolate to prevent graft-versus-host disease after related-donor reduced-intensity conditioning allogeneic haemopoietic stem-cell transplantation: a phase 1/2 trial. The Lancet. Oncology. 15: 87-95. PMID 24295572 DOI: 10.1016/S1470-2045(13)70512-6 |
0.439 |
|
| 2014 |
Van Tassell BW, Arena R, Biondi-Zoccai G, McNair Canada J, Oddi C, Abouzaki NA, Jahangiri A, Falcao RA, Kontos MC, Shah KB, Voelkel NF, Dinarello CA, Abbate A. Effects of interleukin-1 blockade with anakinra on aerobic exercise capacity in patients with heart failure and preserved ejection fraction (from the D-HART pilot study). The American Journal of Cardiology. 113: 321-7. PMID 24262762 DOI: 10.1016/J.Amjcard.2013.08.047 |
0.566 |
|
| 2014 |
Hara N, Alkanani AK, Dinarello CA, Zipris D. Modulation of virus-induced innate immunity and type 1 diabetes by IL-1 blockade Innate Immunity. 20: 574-584. PMID 24062197 DOI: 10.1177/1753425913502242 |
0.66 |
|
| 2014 |
Hara N, Alkanani AK, Dinarello CA, Zipris D. Histone deacetylase inhibitor suppresses virus-induced proinflammatory responses and type 1 diabetes Journal of Molecular Medicine. 92: 93-102. PMID 23982318 DOI: 10.1007/S00109-013-1078-1 |
0.533 |
|
| 2014 |
Bersudsky M, Luski L, Fishman D, White RM, Ziv-Sokolovskaya N, Dotan S, Rider P, Kaplanov I, Aychek T, Dinarello CA, Apte RN, Voronov E. Non-redundant properties of IL-1α and IL-1β during acute colon inflammation in mice. Gut. 63: 598-609. PMID 23793223 DOI: 10.1136/Gutjnl-2012-303329 |
0.683 |
|
| 2014 |
Marcondes AMQ, Sorror ML, Karoopongse E, Furlong T, Lesnikova M, Janciauskiene S, Dinarello CA, Deeg HJ. Alpha 1 Anti-Trypsin (AAT) Offers Potent Therapy for Steroid Resistant Gut Gvhd: Interim Results of a Phase I/II Clinical Study Blood. 124: 3927-3927. DOI: 10.1182/Blood.V124.21.3927.3927 |
0.366 |
|
| 2014 |
Slimani H, Yufeng Z, Yousif N, Ao L, Fullerton D, Dinarello C, Meng X. P504Critical role IL-37 to ameliorate endotoxemic cardiac depression in aging mice: a critical role of suppression cardiodepressant cytokines Cardiovascular Research. 103: S92.3-S92. DOI: 10.1093/Cvr/Cvu091.177 |
0.509 |
|
| 2013 |
Garlanda C, Dinarello CA, Mantovani A. The Interleukin-1 Family: Back to the Future Immunity. 39: 1003-1018. PMID 24332029 DOI: 10.1016/J.Immuni.2013.11.010 |
0.684 |
|
| 2013 |
Kim B, Lee Y, Kim E, Kwak A, Ryoo S, Bae SH, Azam T, Kim S, Dinarello CA. The Interleukin-1α Precursor is Biologically Active and is Likely a Key Alarmin in the IL-1 Family of Cytokines. Frontiers in Immunology. 4: 391. PMID 24312098 DOI: 10.3389/Fimmu.2013.00391 |
0.676 |
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| 2013 |
Cantarini L, Vitale A, Scalini P, Dinarello CA, Rigante D, Franceschini R, Simonini G, Borsari G, Caso F, Lucherini OM, Frediani B, Bertoldi I, Punzi L, Galeazzi M, Cimaz R. Anakinra treatment in drug-resistant Behcet's disease: a case series. Clinical Rheumatology. 34: 1293-301. PMID 24305945 DOI: 10.1007/s10067-013-2443-8 |
0.449 |
|
| 2013 |
Novick D, Kim S, Kaplanski G, Dinarello CA. Interleukin-18, more than a Th1 cytokine. Seminars in Immunology. 25: 439-48. PMID 24275602 DOI: 10.1016/J.Smim.2013.10.014 |
0.698 |
|
| 2013 |
Joosten LAB, Netea MG, Dinarello CA. Interleukin-1β in innate inflammation, autophagy and immunity Seminars in Immunology. 25: 416-424. PMID 24275601 DOI: 10.1016/J.Smim.2013.10.018 |
0.675 |
|
| 2013 |
Dinarello CA. Overview of the interleukin-1 family of ligands and receptors. Seminars in Immunology. 25: 389-393. PMID 24275600 DOI: 10.1016/J.Smim.2013.10.001 |
0.678 |
|
| 2013 |
Dinarello CA, Bufler P. Interleukin-37. Seminars in Immunology. 25: 466-8. PMID 24275599 DOI: 10.1016/j.smim.2013.10.004 |
0.657 |
|
| 2013 |
Dinarello CA, van der Meer JW. Treating inflammation by blocking interleukin-1 in humans. Seminars in Immunology. 25: 469-84. PMID 24275598 DOI: 10.1016/J.Smim.2013.10.008 |
0.697 |
|
| 2013 |
Dinarello CA. The C3a receptor, caspase-1, and release of IL-1β. Blood. 122: 3394-3395. PMID 24235127 DOI: 10.1182/Blood-2013-08-518282 |
0.616 |
|
| 2013 |
Dinarello CA, Novick D, Kim S, Kaplanski G. Interleukin-18 and IL-18 binding protein. Frontiers in Immunology. 4: 289. PMID 24115947 DOI: 10.3389/Fimmu.2013.00289 |
0.697 |
|
| 2013 |
Jonigk D, Al-Omari M, Maegel L, Müller M, Izykowski N, Hong J, Hong K, Kim SH, Dorsch M, Mahadeva R, Laenger F, Kreipe H, Braun A, Shahaf G, Lewis EC, ... ... Dinarello CA, et al. Anti-inflammatory and immunomodulatory properties of α1-antitrypsin without inhibition of elastase. Proceedings of the National Academy of Sciences of the United States of America. 110: 15007-12. PMID 23975926 DOI: 10.1073/Pnas.1309648110 |
0.563 |
|
| 2013 |
Collins CB, Aherne CM, Ehrentraut SF, Gerich ME, McNamee EN, McManus MC, Lebsack MD, Jedlicka P, Azam T, de Zoeten EF, Dinarello CA, Rivera-Nieves J. Alpha-1-antitrypsin therapy ameliorates acute colitis and chronic murine ileitis. Inflammatory Bowel Diseases. 19: 1964-73. PMID 23835442 DOI: 10.1097/Mib.0B013E31829292Aa |
0.535 |
|
| 2013 |
Heinhuis B, Popa CD, van Tits BL, Kim SH, Zeeuwen PL, van den Berg WB, van der Meer JW, van der Vliet JA, Stalenhoef AF, Dinarello CA, Netea MG, Joosten LA. Towards a role of interleukin-32 in atherosclerosis. Cytokine. 64: 433-40. PMID 23727326 DOI: 10.1016/J.Cyto.2013.05.002 |
0.691 |
|
| 2013 |
Lee S, Lee Y, Hong K, Hong J, Bae S, Choi J, Jhun H, Kwak A, Kim E, Jo S, Dinarello CA, Kim S. Effect of recombinant α1-antitrypsin Fc-fused (AAT-Fc)protein on the inhibition of inflammatory cytokine production and streptozotocin-induced diabetes. Molecular Medicine (Cambridge, Mass.). 19: 65-71. PMID 23552726 DOI: 10.2119/Molmed.2012.00308 |
0.594 |
|
| 2013 |
Lupfer C, Thomas PG, Anand PK, Vogel P, Milasta S, Martinez J, Huang G, Green M, Kundu M, Chi H, Xavier RJ, Green DR, Lamkanfi M, Dinarello CA, Doherty PC, et al. Receptor interacting protein kinase 2-mediated mitophagy regulates inflammasome activation during virus infection. Nature Immunology. 14: 480-8. PMID 23525089 DOI: 10.1038/Ni.2563 |
0.542 |
|
| 2013 |
Plantinga TS, Costantini I, Heinhuis B, Huijbers A, Semango G, Kusters B, Netea MG, Hermus AR, Smit JW, Dinarello CA, Joosten LA, Netea-Maier RT. A promoter polymorphism in human interleukin-32 modulates its expression and influences the risk and the outcome of epithelial cell-derived thyroid carcinoma. Carcinogenesis. 34: 1529-35. PMID 23486016 DOI: 10.1093/Carcin/Bgt092 |
0.68 |
|
| 2013 |
Carmi Y, Dotan S, Rider P, Kaplanov I, White MR, Baron R, Abutbul S, Huszar M, Dinarello CA, Apte RN, Voronov E. The Role of IL-1β in the Early Tumor Cell–Induced Angiogenic Response Journal of Immunology. 190: 3500-3509. PMID 23475218 DOI: 10.4049/Jimmunol.1202769 |
0.625 |
|
| 2013 |
Joosten LAB, Heinhuis B, Netea MG, Dinarello CA. Novel insights into the biology of interleukin-32 Cellular and Molecular Life Sciences. 70: 3883-3892. PMID 23463238 DOI: 10.1007/S00018-013-1301-9 |
0.691 |
|
| 2013 |
Abbate A, Van Tassell BW, Biondi-Zoccai G, Kontos MC, Grizzard JD, Spillman DW, Oddi C, Roberts CS, Melchior RD, Mueller GH, Abouzaki NA, Rengel LR, Varma A, Gambill ML, Falcao RA, ... ... Dinarello CA, et al. Effects of interleukin-1 blockade with anakinra on adverse cardiac remodeling and heart failure after acute myocardial infarction [from the Virginia Commonwealth University-Anakinra Remodeling Trial (2) (VCU-ART2) pilot study]. The American Journal of Cardiology. 111: 1394-400. PMID 23453459 DOI: 10.1016/J.Amjcard.2013.01.287 |
0.458 |
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| 2013 |
Kratzer A, Salys J, Nold-Petry C, Cool C, Zamora M, Bowler R, Koczulla AR, Janciauskiene S, Edwards MG, Dinarello CA, Taraseviciene-Stewart L. Role of IL-18 in second-hand smoke-induced emphysema. American Journal of Respiratory Cell and Molecular Biology. 48: 725-32. PMID 23392573 DOI: 10.1165/Rcmb.2012-0173Oc |
0.654 |
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| 2013 |
Levandowski CB, Mailloux CM, Ferrara TM, Gowan K, Ben S, Jin Y, McFann KK, Holland PJ, Fain PR, Dinarello CA, Spritz RA. NLRP1 haplotypes associated with vitiligo and autoimmunity increase interleukin-1β processing via the NLRP1 inflammasome Proceedings of the National Academy of Sciences of the United States of America. 110: 2952-2956. PMID 23382179 DOI: 10.1073/Pnas.1222808110 |
0.621 |
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| 2013 |
Rasmussen TA, Schmeltz Søgaard O, Brinkmann C, Wightman F, Lewin SR, Melchjorsen J, Dinarello C, Østergaard L, Tolstrup M. Comparison of HDAC inhibitors in clinical development: effect on HIV production in latently infected cells and T-cell activation. Human Vaccines & Immunotherapeutics. 9: 993-1001. PMID 23370291 DOI: 10.4161/Hv.23800 |
0.456 |
|
| 2013 |
Gresnigt MS, Rösler B, Jacobs CW, Becker KL, Joosten LA, van der Meer JW, Netea MG, Dinarello CA, van de Veerdonk FL. The IL-36 receptor pathway regulates Aspergillus fumigatus-induced Th1 and Th17 responses. European Journal of Immunology. 43: 416-26. PMID 23147407 DOI: 10.1002/Eji.201242711 |
0.689 |
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| 2013 |
Liu W, Luo Y, Dunn JH, Norris DA, Dinarello CA, Fujita M. Dual role of apoptosis-associated speck-like protein containing a CARD (ASC) in tumorigenesis of human melanoma. The Journal of Investigative Dermatology. 133: 518-27. PMID 22931929 DOI: 10.1038/Jid.2012.317 |
0.55 |
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| 2013 |
Dinarello CA. Review of Tissue-Protective Cytokines Frontiers in Immunology. 4. DOI: 10.3389/Fimmu.2013.00349 |
0.478 |
|
| 2013 |
Nold MF, Nold-Petry CA, Lo C, Li S, Rudloff I, Zepp JA, Azam T, Bufler P, Garlanda C, Mantovani A, Dinarello CA. 187: Interleukin 37 employs the IL-1 family inhibitory receptor SIGIRR and the alpha chain of the IL-18 receptor to suppress innate immunity Cytokine. 63: 287. DOI: 10.1016/J.Cyto.2013.06.190 |
0.583 |
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| 2013 |
Luo Y, Cai X, Liu S, Wang S, Nold-Petry CA, Nold MF, Bufler P, Norris DA, Dinarello CA, Fujita M. 171 : IL-37 suppresses contact hypersensitivity by inducing tolerogenic dendritic cells Cytokine. 63: 283. DOI: 10.1016/J.Cyto.2013.06.174 |
0.502 |
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| 2013 |
Li S, Hong J, Nold MF, Nold-Petry CA, Azam T, Garlanda C, Bufler P, Kim S, Mantovani A, Dinarello CA. 163 : Recombinant IL-37 inhibits LPS induced inflammation in a SIGIRR- and MAPK-dependent manner Cytokine. 63: 281. DOI: 10.1016/J.Cyto.2013.06.166 |
0.592 |
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| 2013 |
Bulau A, Gruschka A, Schwaiger R, Dinarello CA, Bufler P. 30: Anti-IL-37 antibody abrogates the protection in IL-37 transgenic mice to LPS-induced septic shock Cytokine. 63: 250. DOI: 10.1016/J.Cyto.2013.06.033 |
0.58 |
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| 2013 |
Ballak DB, Li S, Diepen JAv, Moschen AR, Jansen H, Hijmans A, Groenhof G, Bufler P, Kersten S, Joosten LAB, Tilg H, Dinarello CA, Netea MG, Tack CJ, Stienstra R. 12: IL-37 protects against obesity-induced inflammation and insulin resistance Cytokine. 63: 245-246. DOI: 10.1016/J.Cyto.2013.06.015 |
0.523 |
|
| 2012 |
Dahllöf MS, Christensen DP, Lundh M, Dinarello CA, Mascagni P, Grunnet LG, Mandrup-Poulsen T. The lysine deacetylase inhibitor Givinostat inhibits β-cell IL-1β induced IL-1β transcription and processing. Islets. 4: 417-22. PMID 23486342 DOI: 10.4161/Isl.23541 |
0.636 |
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| 2012 |
Edwards CK, Green JS, Volk HD, Schiff M, Kotzin BL, Mitsuya H, Kawaguchi T, Sakata KM, Cheronis J, Trollinger D, Bankaitis-Davis D, Dinarello CA, Norris DA, Bevilacqua MP, Fujita M, et al. Combined anti-tumor necrosis factor-α therapy and DMARD therapy in rheumatoid arthritis patients reduces inflammatory gene expression in whole blood compared to DMARD therapy alone. Frontiers in Immunology. 3: 366. PMID 23264777 DOI: 10.3389/Fimmu.2012.00366 |
0.482 |
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| 2012 |
Gresnigt MS, Joosten LA, Verschueren I, van der Meer JW, Netea MG, Dinarello CA, van de Veerdonk FL. Neutrophil-mediated inhibition of proinflammatory cytokine responses. Journal of Immunology (Baltimore, Md. : 1950). 189: 4806-15. PMID 23053514 DOI: 10.4049/Jimmunol.1103551 |
0.657 |
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| 2012 |
Dinarello CA. Keep up the heat on IL-1 Blood. 120: 2538-2539. PMID 23019200 DOI: 10.1182/Blood-2012-08-445254 |
0.654 |
|
| 2012 |
Chiossone L, Audonnet S, Chetaille B, Chasson L, Farnarier C, Berda-Haddad Y, Jordan S, Koszinowski UH, Dalod M, Mazodier K, Novick D, Dinarello CA, Vivier E, Kaplanski G. Protection from Inflammatory Organ Damage in a Murine Model of Hemophagocytic Lymphohistiocytosis Using Treatment with IL-18 Binding Protein Frontiers in Immunology. 3: 239-239. PMID 22891066 DOI: 10.3389/Fimmu.2012.00239 |
0.693 |
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| 2012 |
Heinhuis B, Netea MG, van den Berg WB, Dinarello CA, Joosten LA. Interleukin-32: a predominantly intracellular proinflammatory mediator that controls cell activation and cell death. Cytokine. 60: 321-7. PMID 22878344 DOI: 10.1016/J.Cyto.2012.07.010 |
0.693 |
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| 2012 |
Dinarello CA, Simon A, van der Meer JW. Treating inflammation by blocking interleukin-1 in a broad spectrum of diseases. Nature Reviews. Drug Discovery. 11: 633-52. PMID 22850787 DOI: 10.1038/Nrd3800 |
0.671 |
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| 2012 |
Cavelti-Weder C, Babians-Brunner A, Keller C, Stahel MA, Kurz-Levin M, Zayed H, Solinger AM, Mandrup-Poulsen T, Dinarello CA, Donath MY. Effects of gevokizumab on glycemia and inflammatory markers in type 2 diabetes. Diabetes Care. 35: 1654-62. PMID 22699287 DOI: 10.2337/Dc11-2219 |
0.552 |
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| 2012 |
Dinarello CA. Membrane interleukin-18 revisits membrane IL-1α in T-helper type 1 responses. European Journal of Immunology. 42: 1385-1387. PMID 22678894 DOI: 10.1002/Eji.201242635 |
0.654 |
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| 2012 |
Dinarello CA. Grand Challenge in Inflammation Frontiers in Immunology. 3: 12-12. PMID 22566898 DOI: 10.3389/Fimmu.2012.00012 |
0.545 |
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| 2012 |
Van Tassell BW, Arena RA, Toldo S, Mezzaroma E, Azam T, Seropian IM, Shah K, Canada J, Voelkel NF, Dinarello CA, Abbate A. Enhanced interleukin-1 activity contributes to exercise intolerance in patients with systolic heart failure. Plos One. 7: e33438. PMID 22438931 DOI: 10.1371/Journal.Pone.0033438 |
0.543 |
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| 2012 |
Wang J, Nikrad MP, Travanty EA, Zhou B, Phang T, Gao B, Alford T, Ito Y, Nahreini P, Hartshorn K, Wentworth D, Dinarello CA, Mason RJ. Innate immune response of human alveolar macrophages during influenza A infection. Plos One. 7: e29879. PMID 22396727 DOI: 10.1371/Journal.Pone.0029879 |
0.515 |
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| 2012 |
van de Veerdonk FL, Stoeckman AK, Wu G, Boeckermann AN, Azam T, Netea MG, Joosten LA, van der Meer JW, Hao R, Kalabokis V, Dinarello CA. IL-38 binds to the IL-36 receptor and has biological effects on immune cells similar to IL-36 receptor antagonist. Proceedings of the National Academy of Sciences of the United States of America. 109: 3001-5. PMID 22315422 DOI: 10.1073/Pnas.1121534109 |
0.689 |
|
| 2012 |
Tawara I, Sun Y, Lewis EC, Toubai T, Evers R, Nieves E, Azam T, Dinarello CA, Reddy P. Alpha-1-antitrypsin monotherapy reduces graft-versus-host disease after experimental allogeneic bone marrow transplantation. Proceedings of the National Academy of Sciences of the United States of America. 109: 564-9. PMID 22203983 DOI: 10.1073/Pnas.1117665109 |
0.577 |
|
| 2012 |
Heinhuis B, Koenders MI, van den Berg WB, Netea MG, Dinarello CA, Joosten LA. Interleukin 32 (IL-32) contains a typical α-helix bundle structure that resembles focal adhesion targeting region of focal adhesion kinase-1. The Journal of Biological Chemistry. 287: 5733-43. PMID 22203669 DOI: 10.1074/Jbc.M111.288290 |
0.669 |
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| 2012 |
Gül A, Tugal-Tutkun I, Dinarello CA, Reznikov L, Esen BA, Mirza A, Scannon P, Solinger A. Interleukin-1β-regulating antibody XOMA 052 (gevokizumab) in the treatment of acute exacerbations of resistant uveitis of Behçet's disease: an open-label pilot study Annals of the Rheumatic Diseases. 71: 563-566. PMID 22084392 DOI: 10.1136/Annrheumdis-2011-155143 |
0.477 |
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| 2012 |
Murray DR, Mummidi S, Valente AJ, Yoshida T, Somanna NK, Delafontaine P, Dinarello CA, Chandrasekar B. β2 adrenergic activation induces the expression of IL-18 binding protein, a potent inhibitor of isoproterenol induced cardiomyocyte hypertrophy in vitro and myocardial hypertrophy in vivo. Journal of Molecular and Cellular Cardiology. 52: 206-18. PMID 22004899 DOI: 10.1016/J.Yjmcc.2011.09.022 |
0.682 |
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| 2012 |
Keswani A, Chustz RT, Suh L, Carter R, Peters AT, Tan BK, Chandra R, Kim SH, Azam T, Dinarello CA, Kern RC, Schleimer RP, Kato A. Differential expression of interleukin-32 in chronic rhinosinusitis with and without nasal polyps Allergy: European Journal of Allergy and Clinical Immunology. 67: 25-32. PMID 21899560 DOI: 10.1111/J.1398-9995.2011.02706.X |
0.535 |
|
| 2012 |
Choi SW, DiPersio JF, Braun TM, Hou G, Stockerl-Goldstein K, Tawara I, Levine JE, Sun Y, Couriel DR, Krijanovski OI, Chang L, Magenau JM, Pawarode A, Kitko C, Paczesny S, ... ... Dinarello CA, et al. Targeting Histone Deacetylases As a New Strategy for Graft Versus Host Disease Prevention Blood. 120: 740-740. DOI: 10.1182/Blood.V120.21.740.740 |
0.31 |
|
| 2012 |
Karoopongse E, Janciauskiene S, Dinarello CA, Deeg HJ, Marcondes AMQ. α1 Anti-Trypsin (AAT) Mitigates Hematopoietic Injury and Enhances Bone Marrow Recovery After Total Body Irradiation (TBI) Blood. 120: 4142-4142. DOI: 10.1182/Blood.V120.21.4142.4142 |
0.458 |
|
| 2011 |
Berda-Haddad Y, Robert S, Salers P, Zekraoui L, Farnarier C, Dinarello CA, Dignat-George F, Kaplanski G. Sterile inflammation of endothelial cell-derived apoptotic bodies is mediated by interleukin-1α Proceedings of the National Academy of Sciences of the United States of America. 108: 20684-20689. PMID 22143786 DOI: 10.1073/Pnas.1116848108 |
0.647 |
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| 2011 |
Boraschi D, Lucchesi D, Hainzl S, Leitner M, Maier E, Mangelberger D, Oostingh GJ, Pfaller T, Pixner C, Posselt G, Italiani P, Nold MF, Nold-Petry CA, Bufler P, Dinarello CA. IL-37: a new anti-inflammatory cytokine of the IL-1 family European Cytokine Network. 22: 127-147. PMID 22047735 DOI: 10.1684/Ecn.2011.0288 |
0.69 |
|
| 2011 |
Bai X, Ovrutsky AR, Kartalija M, Chmura K, Kamali A, Honda JR, Oberley-deegan RE, Dinarello CA, Crapo JD, Chang LY, Chan ED. IL-32 expression in the airway epithelial cells of patients with Mycobacterium avium complex lung disease International Immunology. 23: 679-691. PMID 22033195 DOI: 10.1093/Intimm/Dxr075 |
0.671 |
|
| 2011 |
Shainheit MG, Lasocki KW, Finger E, Larkin BM, Smith PM, Sharpe AH, Dinarello CA, Rutitzky LI, Stadecker MJ. The pathogenic Th17 cell response to major schistosome egg antigen is sequentially dependent on IL-23 and IL-1β. Journal of Immunology (Baltimore, Md. : 1950). 187: 5328-35. PMID 22003203 DOI: 10.4049/Jimmunol.1101445 |
0.689 |
|
| 2011 |
Rubartelli A, Gattorno M, Netea MG, Dinarello CA. Interplay between redox status and inflammasome activation Trends in Immunology. 32: 559-566. PMID 21962746 DOI: 10.1016/J.It.2011.08.005 |
0.58 |
|
| 2011 |
Rider P, Carmi Y, Guttman O, Braiman A, Cohen I, Voronov E, White MR, Dinarello CA, Apte RN. IL-1α and IL-1β recruit different myeloid cells and promote different stages of sterile inflammation. Journal of Immunology (Baltimore, Md. : 1950). 187: 4835-43. PMID 21930960 DOI: 10.4049/Jimmunol.1102048 |
0.691 |
|
| 2011 |
Marcondes AM, Li X, Tabellini L, Bartenstein M, Kabacka J, Sale GE, Hansen JA, Dinarello CA, Deeg HJ. Inhibition of IL-32 activation by α-1 antitrypsin suppresses alloreactivity and increases survival in an allogeneic murine marrow transplantation model. Blood. 118: 5031-9. PMID 21900190 DOI: 10.1182/Blood-2011-07-365247 |
0.676 |
|
| 2011 |
McNamee EN, Masterson JC, Jedlicka P, McManus M, Grenz A, Collins CB, Nold MF, Nold-Petry C, Bufler P, Dinarello CA, Rivera-Nieves J. Interleukin 37 expression protects mice from colitis. Proceedings of the National Academy of Sciences of the United States of America. 108: 16711-6. PMID 21873195 DOI: 10.1073/Pnas.1111982108 |
0.692 |
|
| 2011 |
Carta S, Tassi S, Pettinati I, Delfino L, Dinarello CA, Rubartelli A. The rate of interleukin-1beta secretion in different myeloid cells varies with the extent of redox response to Toll-like receptor triggering. Journal of Biological Chemistry. 286: 27069-27080. PMID 21628463 DOI: 10.1074/Jbc.M110.203398 |
0.645 |
|
| 2011 |
Toldo S, Seropian IM, Mezzaroma E, Van Tassell BW, Salloum FN, Lewis EC, Voelkel N, Dinarello CA, Abbate A. Alpha-1 antitrypsin inhibits caspase-1 and protects from acute myocardial ischemia-reperfusion injury. Journal of Molecular and Cellular Cardiology. 51: 244-51. PMID 21600901 DOI: 10.1016/J.Yjmcc.2011.05.003 |
0.478 |
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| 2011 |
Dinarello CA, Fossati G, Mascagni P. Histone deacetylase inhibitors for treating a spectrum of diseases not related to cancer. Molecular Medicine (Cambridge, Mass.). 17: 333-52. PMID 21556484 DOI: 10.2119/Molmed.2011.00116 |
0.489 |
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| 2011 |
Netea MG, Dinarello CA. More than inflammation: interleukin-1beta polymorphisms and the lipid metabolism The Journal of Clinical Endocrinology and Metabolism. 96: 1279-1281. PMID 21543437 DOI: 10.1210/Jc.2011-0685 |
0.69 |
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| 2011 |
Vojinovic J, Damjanov N, D'Urzo C, Furlan A, Susic G, Pasic S, Iagaru N, Stefan M, Dinarello CA. Safety and efficacy of an oral histone deacetylase inhibitor in systemic-onset juvenile idiopathic arthritis. Arthritis and Rheumatism. 63: 1452-8. PMID 21538322 DOI: 10.1002/Art.30238 |
0.453 |
|
| 2011 |
Dinarello CA. A clinical perspective of IL-1β as the gatekeeper of inflammation European Journal of Immunology. 41: 1203-1217. PMID 21523780 DOI: 10.1002/Eji.201141550 |
0.658 |
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| 2011 |
Dustin ML, Rothlein R, Bhan AK, Dinarello CA, Springer TA. Induction by IL 1 and interferon-γ: tissue distribution, biochemistry, and function of a natural adherence molecule (ICAM-1). J. Immunol. 1986. 137: 245-254. Journal of Immunology (Baltimore, Md. : 1950). 186: 5024-33. PMID 21505214 |
0.556 |
|
| 2011 |
Matalon S, Rasmussen TA, Dinarello CA. Histone deacetylase inhibitors for purging HIV-1 from the latent reservoir. Molecular Medicine. 17: 466-472. PMID 21424110 DOI: 10.2119/Molmed.2011.00076 |
0.434 |
|
| 2011 |
Arts RJ, Joosten LA, Dinarello CA, Kullberg BJ, van der Meer JW, Netea MG. TREM-1 interaction with the LPS/TLR4 receptor complex. European Cytokine Network. 22: 11-4. PMID 21393102 DOI: 10.1684/Ecn.2011.0274 |
0.493 |
|
| 2011 |
Moschen AR, Fritz T, Clouston AD, Rebhan I, Bauhofer O, Barrie HD, Powell EE, Kim SH, Dinarello CA, Bartenschlager R, Jonsson JR, Tilg H. Interleukin-32: a new proinflammatory cytokine involved in hepatitis C virus-related liver inflammation and fibrosis. Hepatology (Baltimore, Md.). 53: 1819-29. PMID 21381070 DOI: 10.1002/Hep.24285 |
0.677 |
|
| 2011 |
Furlan A, Monzani V, Reznikov LL, Leoni F, Fossati G, Modena D, Mascagni P, Dinarello CA. Pharmacokinetics, safety and inducible cytokine responses during a phase 1 trial of the oral histone deacetylase inhibitor ITF2357 (givinostat). Molecular Medicine (Cambridge, Mass.). 17: 353-62. PMID 21365126 DOI: 10.2119/Molmed.2011.00020 |
0.628 |
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| 2011 |
Kamari Y, Shaish A, Vax E, Shemesh S, Kandel-Kfir M, Arbel Y, Olteanu S, Barshack I, Dotan S, Voronov E, Dinarello CA, Apte RN, Harats D. Lack of interleukin-1α or interleukin-1β inhibits transformation of steatosis to steatohepatitis and liver fibrosis in hypercholesterolemic mice. Journal of Hepatology. 55: 1086-94. PMID 21354232 DOI: 10.1016/J.Jhep.2011.01.048 |
0.668 |
|
| 2011 |
Zepp JA, Nold-Petry CA, Dinarello CA, Nold MF. Protection from RNA and DNA Viruses by IL-32 Journal of Immunology. 186: 4110-4118. PMID 21346229 DOI: 10.4049/Jimmunol.1000081 |
0.686 |
|
| 2011 |
Veerdonk FLvd, Netea MG, Dinarello CA, Joosten LAB. Inflammasome activation and IL-1β and IL-18 processing during infection Trends in Immunology. 32: 110-116. PMID 21333600 DOI: 10.1016/J.It.2011.01.003 |
0.671 |
|
| 2011 |
Dinarello CA. Interleukin-1 in the pathogenesis and treatment of inflammatory diseases Blood. 117: 3720-3732. PMID 21304099 DOI: 10.1182/Blood-2010-07-273417 |
0.664 |
|
| 2011 |
Kamari Y, Shaish A, Shemesh S, Vax E, Grosskopf I, Dotan S, White M, Voronov E, Dinarello CA, Apte RN, Harats D. Reduced atherosclerosis and inflammatory cytokines in apolipoprotein-E-deficient mice lacking bone marrow-derived interleukin-1α Biochemical and Biophysical Research Communications. 405: 197-203. PMID 21219852 DOI: 10.1016/J.Bbrc.2011.01.008 |
0.675 |
|
| 2011 |
Lewis EC, Blaabjerg L, Størling J, Ronn SG, Mascagni P, Dinarello CA, Mandrup-Poulsen T. The oral histone deacetylase inhibitor ITF2357 reduces cytokines and protects islet β cells in vivo and in vitro. Molecular Medicine (Cambridge, Mass.). 17: 369-77. PMID 21193899 DOI: 10.2119/Molmed.2010.00152 |
0.598 |
|
| 2011 |
Heinhuis B, Koenders MI, van Riel PL, van de Loo FA, Dinarello CA, Netea MG, van den Berg WB, Joosten LA. Tumour necrosis factor alpha-driven IL-32 expression in rheumatoid arthritis synovial tissue amplifies an inflammatory cascade. Annals of the Rheumatic Diseases. 70: 660-7. PMID 21187297 DOI: 10.1136/Ard.2010.139196 |
0.694 |
|
| 2011 |
Dinarello CA. Blocking interleukin‐1β in acute and chronic autoinflammatory diseases Journal of Internal Medicine. 269: 16-28. PMID 21158974 DOI: 10.1111/J.1365-2796.2010.02313.X |
0.511 |
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| 2011 |
Raffeiner B, Botsios C, Dinarello C, Ometto F, Punzi L, Ramonda R. Adult-onset Still's disease with myocarditis successfully treated with the interleukin-1 receptor antagonist anakinra. Joint Bone Spine. 78: 100-101. PMID 21036649 DOI: 10.1016/J.Jbspin.2010.09.014 |
0.457 |
|
| 2011 |
Dinarello C, Arend W, Sims J, Smith D, Blumberg H, O'Neill L, Goldbach-Mansky R, Pizarro TT, Hoffman H, Bufler P, Nold M, Ghezzi P, Mantovani A, Garlanda C, Boraschi D, et al. Erratum: IL-1 family nomenclature (Nature Immunology (2010) 11 (973)) Nature Immunology. 12: 271-271. DOI: 10.1038/Ni0311-271B |
0.371 |
|
| 2011 |
Nold MF, Nold-Petry CA, Zepp JA, Lo C, Garlanda C, Mantovani A, Bufler P, Dinarello CA. CS05-3. Interleukin 37 exerts its anti-inflammatory functions by associating with IL-18Rα and SIGIRR Cytokine. 56: 12. DOI: 10.1016/J.Cyto.2011.07.333 |
0.516 |
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| 2011 |
Nold-Petry CA, Nold MF, Zepp JA, Dinkel H, Palmer BE, Cool CD, Taraseviciene-Stewart L, Kim S, Dinarello CA, Voelkel NF. PS2-031. IL-32 promotes angiogenesis Cytokine. 56: 71-72. DOI: 10.1016/J.Cyto.2011.07.191 |
0.532 |
|
| 2010 |
Migliorini P, Anzilotti C, Pratesi F, Quattroni P, Bargagna M, Dinarello CA, Boraschi D. Serum and urinary levels of IL-18 and its inhibitor IL-18BP in systemic lupus erythematosus European Cytokine Network. 21: 264-271. PMID 21126942 DOI: 10.1684/Ecn.2010.0210 |
0.674 |
|
| 2010 |
Elkabets M, Ribeiro VS, Dinarello CA, Ostrand-Rosenberg S, Di Santo JP, Apte RN, Vosshenrich CA. IL-1β regulates a novel myeloid-derived suppressor cell subset that impairs NK cell development and function. European Journal of Immunology. 40: 3347-57. PMID 21110318 DOI: 10.1002/Eji.201041037 |
0.618 |
|
| 2010 |
Joosten LA, Van De Veerdonk FL, Vonk AG, Boerman OC, Keuter M, Fantuzzi G, Verschueren I, Van Der Poll T, Dinarello CA, Kullberg BJ, Van Der Meer JW, Netea MG. Differential susceptibility to lethal endotoxaemia in mice deficient in IL-1α, IL-1β or IL-1 receptor type I. Apmis : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica. 118: 1000-7. PMID 21091783 DOI: 10.1111/J.1600-0463.2010.02684.X |
0.681 |
|
| 2010 |
Choi J, Bae S, Hong J, Ryoo S, Jhun H, Hong K, Yoon D, Lee S, Her E, Choi W, Kim J, Azam T, Dinarello CA, Kim S. Paradoxical effects of constitutive human IL-32{gamma} in transgenic mice during experimental colitis. Proceedings of the National Academy of Sciences of the United States of America. 107: 21082-6. PMID 21078994 DOI: 10.1073/Pnas.1015418107 |
0.689 |
|
| 2010 |
Dinarello C, Arend W, Sims J, Smith D, Blumberg H, O'Neill L, Goldbach-Mansky R, Pizarro T, Hoffman H, Bufler P, Nold M, Ghezzi P, Mantovani A, Garlanda C, Boraschi D, et al. IL-1 family nomenclature. Nature Immunology. 11: 973. PMID 20959797 DOI: 10.1038/Ni1110-973 |
0.678 |
|
| 2010 |
Nold MF, Nold-Petry CA, Zepp JA, Palmer BE, Bufler P, Dinarello CA. IL-37 is a fundamental inhibitor of innate immunity Nature Immunology. 11: 1014-1022. PMID 20935647 DOI: 10.1038/Ni.1944 |
0.699 |
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| 2010 |
Lundh M, Christensen DP, Rasmussen DN, Mascagni P, Dinarello CA, Billestrup N, Grunnet LG, Mandrup-Poulsen T. Lysine deacetylases are produced in pancreatic beta cells and are differentially regulated by proinflammatory cytokines. Diabetologia. 53: 2569-78. PMID 20878317 DOI: 10.1007/S00125-010-1892-8 |
0.309 |
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| 2010 |
Dinarello CA. How interleukin-1β induces gouty arthritis. Arthritis & Rheumatism. 62: 3140-3144. PMID 20662058 DOI: 10.1002/Art.27663 |
0.654 |
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| 2010 |
Dinarello CA, Donath MY, Mandrup-Poulsen T. Role of IL-1beta in type 2 diabetes Current Opinion in Endocrinology, Diabetes and Obesity. 17: 314-321. PMID 20588114 DOI: 10.1097/Med.0B013E32833Bf6Dc |
0.632 |
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| 2010 |
Maier B, Ogihara T, Trace AP, Tersey SA, Robbins RD, Chakrabarti SK, Nunemaker CS, Stull ND, Taylor CA, Thompson JE, Dondero RS, Lewis EC, Dinarello CA, Nadler JL, Mirmira RG. The unique hypusine modification of eIF5A promotes islet beta cell inflammation and dysfunction in mice. The Journal of Clinical Investigation. 120: 2156-70. PMID 20501948 DOI: 10.1172/Jci38924 |
0.503 |
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| 2010 |
Heinhuis B, Koenders MI, van de Loo FA, van Lent PL, Kim SH, Dinarello CA, Joosten LA, van den Berg WB. IL-32gamma and Streptococcus pyogenes cell wall fragments synergise for IL-1-dependent destructive arthritis via upregulation of TLR-2 and NOD2. Annals of the Rheumatic Diseases. 69: 1866-72. PMID 20472585 DOI: 10.1136/Ard.2009.127399 |
0.679 |
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| 2010 |
Abbate A, Kontos MC, Grizzard JD, Biondi-Zoccai GG, Van Tassell BW, Robati R, Roach LM, Arena RA, Roberts CS, Varma A, Gelwix CC, Salloum FN, Hastillo A, Dinarello CA, Vetrovec GW, et al. Interleukin-1 blockade with anakinra to prevent adverse cardiac remodeling after acute myocardial infarction (Virginia Commonwealth University Anakinra Remodeling Trial [VCU-ART] Pilot study). The American Journal of Cardiology. 105: 1371-1377.e1. PMID 20451681 DOI: 10.1016/J.Amjcard.2009.12.059 |
0.575 |
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| 2010 |
Dinarello CA. Why not treat human cancer with interleukin-1 blockade? Cancer and Metastasis Reviews. 29: 317-329. PMID 20422276 DOI: 10.1007/S10555-010-9229-0 |
0.695 |
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| 2010 |
Abbate A, Van Tassell BW, Seropian IM, Toldo S, Robati R, Varma A, Salloum FN, Smithson L, Dinarello CA. Interleukin-1beta modulation using a genetically engineered antibody prevents adverse cardiac remodelling following acute myocardial infarction in the mouse. European Journal of Heart Failure. 12: 319-22. PMID 20335350 DOI: 10.1093/Eurjhf/Hfq017 |
0.442 |
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| 2010 |
Dinarello CA. Anti-inflammatory Agents: Present and Future Cell. 140: 935-950. PMID 20303881 DOI: 10.1016/J.Cell.2010.02.043 |
0.486 |
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| 2010 |
Matalon S, Palmer BE, Nold MF, Furlan A, Kassu A, Fossati G, Mascagni P, Dinarello CA. The histone deacetylase inhibitor ITF2357 decreases surface CXCR4 and CCR5 expression on CD4(+) T-cells and monocytes and is superior to valproic acid for latent HIV-1 expression in vitro. Journal of Acquired Immune Deficiency Syndromes (1999). 54: 1-9. PMID 20300007 DOI: 10.1097/Qai.0B013E3181D3Dca3 |
0.461 |
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| 2010 |
Dinarello CA. IL-1: discoveries, controversies and future directions. European Journal of Immunology. 40: 599-606. PMID 20201008 DOI: 10.1002/Eji.201040319 |
0.686 |
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| 2010 |
Chou RC, Dinarello CA, Ferry JA, Cin PD. A 36-year-old woman with recurrent high-grade fevers, hypotension, and hypertriglyceridemia Arthritis Care and Research. 62: 128-136. PMID 20191502 DOI: 10.1002/Acr.20024 |
0.454 |
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| 2010 |
Bai X, Kim SH, Azam T, McGibney MT, Huang H, Dinarello CA, Chan ED. IL-32 is a host protective cytokine against Mycobacterium tuberculosis in differentiated THP-1 human macrophages. Journal of Immunology (Baltimore, Md. : 1950). 184: 3830-40. PMID 20190143 DOI: 10.4049/Jimmunol.0901913 |
0.627 |
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| 2010 |
Cohen I, Rider P, Carmi Y, Braiman A, Dotan S, White MR, Voronov E, Martin MU, Dinarello CA, Apte RN. Differential release of chromatin-bound IL-1alpha discriminates between necrotic and apoptotic cell death by the ability to induce sterile inflammation. Proceedings of the National Academy of Sciences of the United States of America. 107: 2574-9. PMID 20133797 DOI: 10.1073/Pnas.0915018107 |
0.671 |
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| 2010 |
van de Veerdonk FL, Smeekens SP, Joosten LA, Kullberg BJ, Dinarello CA, van der Meer JW, Netea MG. Reactive oxygen species-independent activation of the IL-1beta inflammasome in cells from patients with chronic granulomatous disease. Proceedings of the National Academy of Sciences of the United States of America. 107: 3030-3. PMID 20133696 DOI: 10.1073/Pnas.0914795107 |
0.666 |
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| 2010 |
Okamoto M, Liu W, Luo Y, Tanaka A, Cai X, Norris DA, Dinarello CA, Fujita M. Constitutively active inflammasome in human melanoma cells mediating autoinflammation via caspase-1 processing and secretion of interleukin-1beta. The Journal of Biological Chemistry. 285: 6477-88. PMID 20038581 DOI: 10.1074/Jbc.M109.064907 |
0.683 |
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| 2010 |
Silliman CC, Kelher MR, Gamboni-Robertson F, Hamiel C, England KM, Dinarello CA, Wyman TH, Khan SY, McLaughlin NJ, Bercovitz RS, Banerjee A. Tumor necrosis factor-alpha causes release of cytosolic interleukin-18 from human neutrophils. American Journal of Physiology. Cell Physiology. 298: C714-24. PMID 19907017 DOI: 10.1152/Ajpcell.00011.2009 |
0.666 |
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| 2010 |
Hong J, Bae S, Kang Y, Yoon D, Bai X, Chan ED, Azam T, Dinarello CA, Lee S, Her E, Rho G, Kim S. Suppressing IL-32 in monocytes impairs the induction of the proinflammatory cytokines TNFalpha and IL-1beta. Cytokine. 49: 171-6. PMID 19880327 DOI: 10.1016/J.Cyto.2009.10.003 |
0.703 |
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| 2010 |
Novick D, Elbirt D, Miller G, Dinarello CA, Rubinstein M, Sthoeger ZM. High circulating levels of free interleukin-18 in patients with active SLE in the presence of elevated levels of interleukin-18 binding protein. Journal of Autoimmunity. 34: 121-6. PMID 19699611 DOI: 10.1016/J.Jaut.2009.08.002 |
0.672 |
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| 2010 |
Marcondes AMQ, Tabellini L, Hansen JA, Dinarello CA, Deeg HJ. Interleukin-32, α1 Anti-Trypsin (AAT-1) and Graft-Versus-Host-Disease Blood. 116: 522-522. DOI: 10.1182/Blood.V116.21.522.522 |
0.58 |
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| 2010 |
Kato A, Keswani A, Chustz RT, Peters A, Chandra R, Carter R, Suh L, Norton J, Harris KE, Conley D, Grammer LC, Kim S, Dinarello CA, Kern RC, Schleimer RP. IL-32 Expression in Chronic Rhinosinusitis The Journal of Allergy and Clinical Immunology. 125. DOI: 10.1016/J.Jaci.2009.12.960 |
0.5 |
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| 2010 |
Voronov E, Song X, Dvorkin T, Dotan S, Elkabets M, Carmi Y, Dinarello CA, Apte RN. IL-1-7 Differential roles of IL-1 alpha and IL-1 beta in the malignant process Cytokine. 52: 10-10. DOI: 10.1016/J.Cyto.2010.07.045 |
0.533 |
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| 2010 |
Dinarello CA. IL-1-1 History of IL-1 discoveries Cytokine. 52: 9-9. DOI: 10.1016/J.Cyto.2010.07.039 |
0.548 |
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| 2010 |
Nold MF, Nold-Petry CA, Zepp JA, Bufler P, Palmer BE, Dinarello CA. PL-4 IL-36 (Formerly IL-1F7) suppresses innate immunity by inhibiting inflammatory cytokines and dendritic cell activation by association with SMAD3 Cytokine. 52: 3-4. DOI: 10.1016/J.Cyto.2010.07.019 |
0.543 |
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| 2009 |
Joosten LA, Netea MG, Fantuzzi G, Koenders MI, Helsen MM, Sparrer H, Pham CT, van der Meer JW, Dinarello CA, van den Berg WB. Inflammatory arthritis in caspase 1 gene-deficient mice: contribution of proteinase 3 to caspase 1-independent production of bioactive interleukin-1beta. Arthritis and Rheumatism. 60: 3651-62. PMID 19950280 DOI: 10.1002/Art.25006 |
0.547 |
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| 2009 |
Wang M, Tan J, Wang Y, Meldrum KK, Dinarello CA, Meldrum DR. IL-18 binding protein-expressing mesenchymal stem cells improve myocardial protection after ischemia or infarction. Proceedings of the National Academy of Sciences of the United States of America. 106: 17499-17504. PMID 19805173 DOI: 10.1073/Pnas.0908924106 |
0.633 |
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| 2009 |
Favilli F, Anzilotti C, Martinelli L, Quattroni P, De Martino S, Pratesi F, Neumann D, Beermann S, Novick D, Dinarello CA, Boraschi D, Migliorini P. IL-18 activity in systemic lupus erythematosus. Annals of the New York Academy of Sciences. 1173: 301-9. PMID 19758166 DOI: 10.1111/J.1749-6632.2009.04742.X |
0.669 |
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| 2009 |
Carmi Y, Voronov E, Dotan S, Lahat N, Rahat MA, Fogel M, Huszar M, White MR, Dinarello CA, Apte RN. The role of macrophage-derived IL-1 in induction and maintenance of angiogenesis. Journal of Immunology (Baltimore, Md. : 1950). 183: 4705-14. PMID 19752225 DOI: 10.4049/Jimmunol.0901511 |
0.664 |
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| 2009 |
Shein NA, Grigoriadis N, Alexandrovich AG, Simeonidou C, Lourbopoulos A, Polyzoidou E, Trembovler V, Mascagni P, Dinarello CA, Shohami E. Histone deacetylase inhibitor ITF2357 is neuroprotective, improves functional recovery, and induces glial apoptosis following experimental traumatic brain injury. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 23: 4266-75. PMID 19723705 DOI: 10.1096/Fj.09-134700 |
0.445 |
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| 2009 |
Kliger Y, Levy O, Oren A, Ashkenazy H, Tiran Z, Novik A, Rosenberg A, Amir A, Wool A, Toporik A, Schreiber E, Eshel D, Levine Z, Cohen Y, Nold-Petry C, ... Dinarello CA, et al. Peptides modulating conformational changes in secreted chaperones: from in silico design to preclinical proof of concept. Proceedings of the National Academy of Sciences of the United States of America. 106: 13797-801. PMID 19666568 DOI: 10.1073/Pnas.0906514106 |
0.551 |
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| 2009 |
Nold-Petry CA, Nold MF, Nielsen JW, Bustamante A, Zepp JA, Storm KA, Hong JW, Kim SH, Dinarello CA. Increased cytokine production in interleukin-18 receptor alpha-deficient cells is associated with dysregulation of suppressors of cytokine signaling. The Journal of Biological Chemistry. 284: 25900-11. PMID 19592492 DOI: 10.1074/Jbc.M109.004184 |
0.697 |
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| 2009 |
Olson JL, Courtney RJ, Rouhani B, Mandava N, Dinarello CA. Intravitreal anakinra inhibits choroidal neovascular membrane growth in a rat model. Ocular Immunology and Inflammation. 17: 195-200. PMID 19585363 DOI: 10.1080/09273940802710705 |
0.507 |
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| 2009 |
Dinarello CA. Hyperosmolar sodium chloride, p38 mitogen activated protein and cytokine-mediated inflammation. Seminars in Dialysis. 22: 256-259. PMID 19573005 DOI: 10.1111/J.1525-139X.2009.00568.X |
0.607 |
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| 2009 |
Kleinnijenhuis J, Joosten LA, van de Veerdonk FL, Savage N, van Crevel R, Kullberg BJ, van der Ven A, Ottenhoff TH, Dinarello CA, van der Meer JW, Netea MG. Transcriptional and inflammasome-mediated pathways for the induction of IL-1beta production by Mycobacterium tuberculosis. European Journal of Immunology. 39: 1914-22. PMID 19544485 DOI: 10.1002/Eji.200839115 |
0.621 |
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| 2009 |
Bani-Hani AH, Leslie JA, Asanuma H, Dinarello CA, Campbell MT, Meldrum DR, Zhang H, Hile K, Meldrum KK. IL-18 neutralization ameliorates obstruction-induced epithelial-mesenchymal transition and renal fibrosis. Kidney International. 76: 500-11. PMID 19536084 DOI: 10.1038/Ki.2009.216 |
0.633 |
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| 2009 |
Dinarello CA. Interleukin-1β and the Autoinflammatory Diseases The New England Journal of Medicine. 360: 2467-2470. PMID 19494224 DOI: 10.1056/Nejme0811014 |
0.594 |
|
| 2009 |
Sun Y, Chin YE, Weisiger E, Malter C, Tawara I, Toubai T, Gatza E, Mascagni P, Dinarello CA, Reddy P. Cutting edge: Negative regulation of dendritic cells through acetylation of the nonhistone protein STAT-3. Journal of Immunology (Baltimore, Md. : 1950). 182: 5899-903. PMID 19414739 DOI: 10.4049/Jimmunol.0804388 |
0.47 |
|
| 2009 |
Ben-Sasson SZ, Hu-Li J, Quiel J, Cauchetaux S, Ratner M, Shapira I, Dinarello CA, Paul WE. IL-1 acts directly on CD4 T cells to enhance their antigen-driven expansion and differentiation. Proceedings of the National Academy of Sciences of the United States of America. 106: 7119-24. PMID 19359475 DOI: 10.1073/Pnas.0902745106 |
0.662 |
|
| 2009 |
Elkabets M, Krelin Y, Dotan S, Cerwenka A, Porgador A, Lichtenstein RG, White MR, Zoller M, Iwakura Y, Dinarello CA, Voronov E, Apte RN. Host-Derived Interleukin-1α Is Important in Determining the Immunogenicity of 3-Methylcholantrene Tumor Cells Journal of Immunology. 182: 4874-4881. PMID 19342666 DOI: 10.4049/Jimmunol.0803916 |
0.665 |
|
| 2009 |
Dinarello CA. Immunological and Inflammatory Functions of the Interleukin-1 Family Annual Review of Immunology. 27: 519-550. PMID 19302047 DOI: 10.1146/Annurev.Immunol.021908.132612 |
0.644 |
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| 2009 |
Nold-Petry CA, Nold MF, Zepp JA, Kim SH, Voelkel NF, Dinarello CA. IL-32-dependent effects of IL-1beta on endothelial cell functions. Proceedings of the National Academy of Sciences of the United States of America. 106: 3883-8. PMID 19228941 DOI: 10.1073/Pnas.0813334106 |
0.691 |
|
| 2009 |
van de Veerdonk FL, Joosten LA, Devesa I, Mora-Montes HM, Kanneganti TD, Dinarello CA, van der Meer JW, Gow NA, Kullberg BJ, Netea MG. Bypassing pathogen-induced inflammasome activation for the regulation of interleukin-1beta production by the fungal pathogen Candida albicans. The Journal of Infectious Diseases. 199: 1087-96. PMID 19222370 DOI: 10.1086/597274 |
0.625 |
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| 2009 |
Pott GB, Chan ED, Dinarello CA, Shapiro L. α-1-Antitrypsin is an endogenous inhibitor of proinflammatory cytokine production in whole blood Journal of Leukocyte Biology. 85: 886-895. PMID 19197072 DOI: 10.1189/Jlb.0208145 |
0.674 |
|
| 2009 |
Dinarello CA. Targeting the Pathogenic Role of Interleukin 1β in the Progression of Smoldering/Indolent Myeloma to Active Disease Mayo Clinic Proceedings. 84: 105-107. PMID 19181642 DOI: 10.4065/84.2.105 |
0.652 |
|
| 2009 |
Dinarello CA. Inflammation in Human Disease: Anticytokine Therapy Biology of Blood and Marrow Transplantation. 15: 134-136. PMID 19147092 DOI: 10.1016/J.Bbmt.2008.11.006 |
0.469 |
|
| 2009 |
Netea MG, Nold-Petry CA, Nold MF, Joosten LA, Opitz B, van der Meer JH, van de Veerdonk FL, Ferwerda G, Heinhuis B, Devesa I, Funk CJ, Mason RJ, Kullberg BJ, Rubartelli A, van der Meer JW, ... Dinarello CA, et al. Differential requirement for the activation of the inflammasome for processing and release of IL-1beta in monocytes and macrophages. Blood. 113: 2324-35. PMID 19104081 DOI: 10.1182/Blood-2008-03-146720 |
0.621 |
|
| 2009 |
Arcaroli JJ, Hokanson JE, Abraham E, Geraci M, Murphy JR, Bowler RP, Dinarello CA, Silveira L, Sankoff J, Heyland D, Wischmeyer P, Crapo JD. Extracellular superoxide dismutase haplotypes are associated with acute lung injury and mortality American Journal of Respiratory and Critical Care Medicine. 179: 105-112. PMID 18948423 DOI: 10.1164/Rccm.200710-1566Oc |
0.457 |
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| 2009 |
Choi JD, Bae SY, Hong JW, Azam T, Dinarello CA, Her E, Choi WS, Kim BK, Lee CK, Yoon DY, Kim SJ, Kim SH. Identification of the most active interleukin-32 isoform. Immunology. 126: 535-42. PMID 18771438 DOI: 10.1111/J.1365-2567.2008.02917.X |
0.699 |
|
| 2009 |
Novick D, Elbirt D, Dinarello CA, Rubinstein M, Sthoeger ZM. Interleukin-18 binding protein in the sera of patients with Wegener's granulomatosis. Journal of Clinical Immunology. 29: 38-45. PMID 18594952 DOI: 10.1007/S10875-008-9217-0 |
0.547 |
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| 2009 |
Mandrup-Poulsen T, Egeberg J, Nerup J, Bendtzen K, Nielsen JH, Dinarello CA. Ultrastructural studies of time-course and cellular specificity of interleukin-1 mediated islet cytotoxicity. Acta Pathologica Microbiologica Scandinavica Series C: Immunology. 95: 55-63. PMID 3300162 DOI: 10.1111/J.1699-0463.1987.Tb00009.X |
0.394 |
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| 2009 |
Dinarello CA. Editorial: Interleukin-1: the paradigm for multifunctional inflammatory cytokines Journal of Medical Sciences. 1: 8-9. DOI: 10.2174/1996327000801010008 |
0.318 |
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| 2009 |
Shahaf G, DeFelice N, Ficek C, Friedman F, Dinarello CA, Lewis EC. Islet allograft survival and anti-inflammatory cytokine profile are provided by circulating transgenic lung-specific alpha-1-antitrypsin Cytokine. 48: 105. DOI: 10.1016/J.Cyto.2009.07.441 |
0.301 |
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| 2009 |
Lewis EC, Blaabjerg L, Størling J, Ronn SG, Mascagni P, Dinarello CA, Mandrup-Poulsen T. The oral histone deacetylase inhibitor ITF2357 reduces cytokine production, cytokine activities and protects islet β-cells in vivo and in vitro Cytokine. 48: 92-93. DOI: 10.1016/J.Cyto.2009.07.387 |
0.358 |
|
| 2009 |
Nold MF, Nold-Petry CA, Zepp JA, Bufler P, Dinarello CA. IL-1 family member 7 is a fundamental inhibitor of innate immunity Cytokine. 48: 68-69. DOI: 10.1016/J.Cyto.2009.07.224 |
0.451 |
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| 2009 |
Fritz T, Moschen AR, Jonsson JR, Woerz I, Clouston AD, Kim S, Dinarello CA, Bartenschlager R, Powell EE, Tilg H. IL:32: A new pro-inflammatory cytokine involved in HCV-related liver inflammation and fibrosis Hepatology. 50. DOI: 10.1002/Hep.23300 |
0.443 |
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| 2008 |
Kim S, Lee S, Her E, Bae S, Choi J, Hong J, Jaekal J, Yoon D, Azam T, Dinarello CA, Kim S. Proteinase 3-processed form of the recombinant IL-32 separate domain. Bmb Reports. 41: 814-9. PMID 19017495 DOI: 10.5483/Bmbrep.2008.41.11.814 |
0.688 |
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| 2008 |
Lewis EC, Mizrahi M, Toledano M, Defelice N, Wright JL, Churg A, Shapiro L, Dinarello CA. alpha1-Antitrypsin monotherapy induces immune tolerance during islet allograft transplantation in mice. Proceedings of the National Academy of Sciences of the United States of America. 105: 16236-41. PMID 18852465 DOI: 10.1073/Pnas.0807627105 |
0.548 |
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| 2008 |
Moore CC, Martin EN, Lee G, Taylor C, Dondero R, Reznikov LL, Dinarello C, Thompson J, Scheld WM. Eukaryotic translation initiation factor 5A small interference RNA-liposome complexes reduce inflammation and increase survival in murine models of severe sepsis and acute lung injury. The Journal of Infectious Diseases. 198: 1407-14. PMID 18793104 DOI: 10.1086/592222 |
0.468 |
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| 2008 |
Bosisio D, Vulcano M, Del Prete A, Sironi M, Salvi V, Salogni L, Riboldi E, Leoni F, Dinarello CA, Girolomoni G, Sozzani S. Blocking TH17-polarizing cytokines by histone deacetylase inhibitors in vitro and in vivo. Journal of Leukocyte Biology. 84: 1540-8. PMID 18780875 DOI: 10.1189/Jlb.0708401 |
0.592 |
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| 2008 |
He Z, Lu L, Altmann C, Hoke TS, Ljubanovic D, Jani A, Dinarello CA, Faubel S, Edelstein CL. Interleukin-18 binding protein transgenic mice are protected against ischemic acute kidney injury. American Journal of Physiology. Renal Physiology. 295: F1414-21. PMID 18753296 DOI: 10.1152/ajprenal.90288.2008 |
0.625 |
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| 2008 |
Botsios C, Sfriso P, Furlan A, Punzi L, Dinarello CA. Resistant Behçet disease responsive to anakinra. Annals of Internal Medicine. 149: 284-286. PMID 18711165 DOI: 10.7326/0003-4819-149-4-200808190-00018 |
0.432 |
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| 2008 |
Calabrese F, Baraldo S, Bazzan E, Lunardi F, Rea F, Maestrelli P, Turato G, Lokar-Oliani K, Papi A, Zuin R, Sfriso P, Balestro E, Dinarello CA, Saetta M. IL-32, a novel proinflammatory cytokine in chronic obstructive pulmonary disease. American Journal of Respiratory and Critical Care Medicine. 178: 894-901. PMID 18703789 DOI: 10.1164/Rccm.200804-646Oc |
0.644 |
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| 2008 |
Ludwiczek O, Vannier E, Moschen A, Salazar-Montes A, Borggraefe I, Gabay C, Enrich B, Kaser A, Siegmund B, Dinarello C, Tilg H. Impaired counter-regulation of interleukin-1 by the soluble IL-1 receptor type II in patients with chronic liver disease Scandinavian Journal of Gastroenterology. 43: 1360-1365. PMID 18609176 DOI: 10.1080/00365520802179925 |
0.682 |
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| 2008 |
Reddy P, Sun Y, Toubai T, Duran-Struuck R, Clouthier SG, Weisiger E, Maeda Y, Tawara I, Krijanovski O, Gatza E, Liu C, Malter C, Mascagni P, Dinarello CA, Ferrara JL. Histone deacetylase inhibition modulates indoleamine 2,3-dioxygenase-dependent DC functions and regulates experimental graft-versus-host disease in mice. The Journal of Clinical Investigation. 118: 2562-73. PMID 18568076 DOI: 10.1172/Jci34712 |
0.475 |
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| 2008 |
Nold MF, Nold-Petry CA, Pott GB, Zepp JA, Saavedra MT, Kim S, Dinarello CA. Endogenous IL-32 Controls Cytokine and HIV-1 Production Journal of Immunology. 181: 557-565. PMID 18566422 DOI: 10.4049/Jimmunol.181.1.557 |
0.664 |
|
| 2008 |
Sennello JA, Fayad R, Pini M, Gove ME, Ponemone V, Cabay RJ, Siegmund B, Dinarello CA, Fantuzzi G. Interleukin-18, together with interleukin-12, induces severe acute pancreatitis in obese but not in nonobese leptin-deficient mice Proceedings of the National Academy of Sciences of the United States of America. 105: 8085-8090. PMID 18515422 DOI: 10.1073/Pnas.0804091105 |
0.566 |
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| 2008 |
Cha J, Wang Z, Ao L, Zou N, Dinarello CA, Banerjee A, Fullerton DA, Meng X. Cytokines link Toll-like receptor 4 signaling to cardiac dysfunction after global myocardial ischemia. The Annals of Thoracic Surgery. 85: 1678-85. PMID 18442564 DOI: 10.1016/J.Athoracsur.2008.01.043 |
0.557 |
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| 2008 |
Dinarello CA, Muegge K, Durum SK. Measurement of soluble and membrane-bound interleukin 1 using a fibroblast bioassay. Current Protocols in Immunology. Unit 6.2. PMID 18432810 DOI: 10.1002/0471142735.Im0602S37 |
0.562 |
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| 2008 |
Sharma S, Kulk N, Nold MF, Gräf R, Kim S, Reinhardt D, Dinarello CA, Bufler P. The IL-1 family member 7b translocates to the nucleus and down-regulates proinflammatory cytokines. Journal of Immunology. 180: 5477-5482. PMID 18390730 DOI: 10.4049/Jimmunol.180.8.5477 |
0.696 |
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| 2008 |
Netea MG, Lewis EC, Azam T, Joosten LA, Jaekal J, Bae SY, Dinarello CA, Kim SH. Interleukin-32 induces the differentiation of monocytes into macrophage-like cells. Proceedings of the National Academy of Sciences of the United States of America. 105: 3515-20. PMID 18296636 DOI: 10.1073/Pnas.0712381105 |
0.686 |
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| 2008 |
Marcondes AM, Mhyre AJ, Stirewalt DL, Kim SH, Dinarello CA, Deeg HJ. Dysregulation of IL-32 in myelodysplastic syndrome and chronic myelomonocytic leukemia modulates apoptosis and impairs NK function. Proceedings of the National Academy of Sciences of the United States of America. 105: 2865-70. PMID 18287021 DOI: 10.1073/Pnas.0712391105 |
0.675 |
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| 2008 |
Kim KH, Shim JH, Seo EH, Cho MC, Kang JW, Kim SH, Yu DY, Song EY, Lee HG, Sohn JH, Kim J, Dinarello CA, Yoon DY. Interleukin-32 monoclonal antibodies for immunohistochemistry, Western blotting, and ELISA. Journal of Immunological Methods. 333: 38-50. PMID 18252253 DOI: 10.1016/J.Jim.2007.12.017 |
0.679 |
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| 2008 |
Saavedra MT, Patterson AD, West J, Randell SH, Riches DW, Malcolm KC, Cool CD, Nick JA, Dinarello CA. Abrogation of anti-inflammatory transcription factor LKLF in neutrophil-dominated airways. American Journal of Respiratory Cell and Molecular Biology. 38: 679-88. PMID 18218994 DOI: 10.1165/Rcmb.2007-0282Oc |
0.57 |
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| 2008 |
Glauben R, Batra A, Stroh T, Erben U, Fedke I, Lehr HA, Leoni F, Mascagni P, Dinarello CA, Zeitz M, Siegmund B. Histone deacetylases: novel targets for prevention of colitis-associated cancer in mice. Gut. 57: 613-22. PMID 18194985 DOI: 10.1136/Gut.2007.134650 |
0.366 |
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| 2008 |
Jaekal J, Abraham E, Azam T, Netea MG, Dinarello CA, Lim JS, Yang Y, Yoon DY, Kim SH. Individual LPS responsiveness depends on the variation of toll-like receptor (TLR) expression level. Journal of Microbiology and Biotechnology. 17: 1862-7. PMID 18092472 |
0.415 |
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| 2008 |
Manzer R, Dinarello CA, McConville G, Mason RJ. Ozone exposure of macrophages induces an alveolar epithelial chemokine response through IL-1alpha. American Journal of Respiratory Cell and Molecular Biology. 38: 318-23. PMID 17901407 DOI: 10.1165/Rcmb.2007-0250Oc |
0.676 |
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| 2008 |
Rustgi VK, Jones DB, Dinarello CA, Hoofnagle JH. Lymphokines and bile secretion in the rat Liver. 7: 149-154. PMID 2956476 DOI: 10.1111/J.1600-0676.1987.Tb00335.X |
0.311 |
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| 2008 |
Dinarello C. PL-21 Blocking IL-1 in auto-inflammatory diseases Cytokine. 43: 334-334. DOI: 10.1016/J.Cyto.2008.07.463 |
0.531 |
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| 2008 |
Pott GB, Chan ED, Dinarello CA, Shapiro L. 282 Alpha-1-antitrypsin is an endogenous and specific inhibitor of pro-inflammatory cytokine production in whole blood Cytokine. 43: 310-310. DOI: 10.1016/J.Cyto.2008.07.364 |
0.326 |
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| 2008 |
Nold-Petry CA, Nold MF, Zepp JA, Walborn AK, Dinarello CA. 123 Functions of IL-32 in human vascular endothelial cells Cytokine. 43: 265-265. DOI: 10.1016/J.Cyto.2008.07.165 |
0.45 |
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| 2008 |
Nold MF, Nold-Petry CA, Zepp JA, Bufler P, Dinarello CA. 120 The IL-1 family member IL-1F7 reduces innate immunity by inhibiting Toll-like receptor and IL-1 signaling pathways Cytokine. 43: 264-264. DOI: 10.1016/J.Cyto.2008.07.162 |
0.53 |
|
| 2007 |
Dinarello CA. Historical insights into cytokines. European Journal of Immunology. 37. PMID 17972343 DOI: 10.1002/Eji.200737772 |
0.581 |
|
| 2007 |
Meng X, Ao L, Song Y, Babu A, Yang X, Wang M, Weyant MJ, Dinarello CA, Cleveland JC, Fullerton DA. Expression of functional Toll-like receptors 2 and 4 in human aortic valve interstitial cells: potential roles in aortic valve inflammation and stenosis. American Journal of Physiology. Cell Physiology. 294: C29-35. PMID 17942642 DOI: 10.1152/Ajpcell.00137.2007 |
0.52 |
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| 2007 |
Lavi G, Voronov E, Dinarello CA, Apte RN, Cohen S. Sustained delivery of IL-1Ra from biodegradable microspheres reduces the number of murine B16 melanoma lung metastases Journal of Controlled Release. 123: 123-130. PMID 17900737 DOI: 10.1016/J.Jconrel.2007.07.015 |
0.649 |
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| 2007 |
Dinarello CA. Mutations in cryopyrin : Bypassing roadblocks in the caspase 1 inflammasome for interleukin-1β secretion and disease activity Arthritis & Rheumatism. 56: 2817-2822. PMID 17763412 DOI: 10.1002/Art.22841 |
0.487 |
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| 2007 |
Ao L, Song Y, Fullerton DA, Dinarello CA, Meng X. The interaction between myocardial depressant factors in endotoxemic cardiac dysfunction: role of TNF-alpha in TLR4-mediated ICAM-1 expression. Cytokine. 38: 124-9. PMID 17683945 DOI: 10.1016/J.Cyto.2007.05.018 |
0.491 |
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| 2007 |
Yoon D, Dinarello CA. Differential Effects of Anti-IL-1R Accessory Protein Antibodies on IL-1α or IL-1β-induced Production of PGE₂ and IL-6 from 3T3-L1 Cells Journal of Biochemistry and Molecular Biology. 40: 562-570. PMID 17669273 DOI: 10.5483/Bmbrep.2007.40.4.562 |
0.685 |
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| 2007 |
Pott GB, Sailer CA, Porat R, Peskind RL, Fuchs AC, Angel JB, Skolnik PR, Jacobson MA, Giordano MF, Lebeaut A, Grint PC, Dinarello CA, Shapiro L. Effect of a four-week course of interleukin-10 on cytokine production in a placebo-controlled study of HIV-1-infected subjects. European Cytokine Network. 18: 49-58. PMID 17594937 DOI: 10.1684/Ecn.2007.0094 |
0.683 |
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| 2007 |
Tan ZS, Beiser AS, Vasan RS, Roubenoff R, Dinarello CA, Harris TB, Benjamin EJ, Au R, Kiel DP, Wolf PA, Seshadri S. Inflammatory markers and the risk of Alzheimer disease: the Framingham Study. Neurology. 68: 1902-8. PMID 17536046 DOI: 10.1212/01.Wnl.0000263217.36439.Da |
0.309 |
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| 2007 |
Dinarello CA. A Signal for the Caspase-1 Inflammasome Free of TLR Immunity. 26: 383-385. PMID 17459804 DOI: 10.1016/J.Immuni.2007.04.005 |
0.613 |
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| 2007 |
Auron PE, Webb AC, Rosenwasser LJ, Mucci SF, Rich A, Wolff SM, Dinarello CA. Nucleotide sequence of human monocyte interleukin 1 precursor cDNA. Proc. Natl. Acad. Sci. USA 1984. 81: 7907-7911. Journal of Immunology (Baltimore, Md. : 1950). 178: 5413-7. PMID 17442920 |
0.774 |
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| 2007 |
Faubel S, Lewis EC, Reznikov L, Ljubanovic D, Hoke TS, Somerset H, Oh DJ, Lu L, Klein CL, Dinarello CA, Edelstein CL. Cisplatin-induced acute renal failure is associated with an increase in the cytokines interleukin (IL)-1beta, IL-18, IL-6, and neutrophil infiltration in the kidney. The Journal of Pharmacology and Experimental Therapeutics. 322: 8-15. PMID 17400889 DOI: 10.1124/Jpet.107.119792 |
0.684 |
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| 2007 |
Hurgin V, Novick D, Werman A, Dinarello CA, Rubinstein M. Antiviral and immunoregulatory activities of IFN-gamma depend on constitutively expressed IL-1alpha. Proceedings of the National Academy of Sciences of the United States of America. 104: 5044-9. PMID 17360358 DOI: 10.1073/Pnas.0611608104 |
0.664 |
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| 2007 |
Boraschi D, Dinarello CA. IL-18 in autoimmunity: review. European Cytokine Network. 17: 224-52. PMID 17353157 |
0.631 |
|
| 2007 |
Dinarello CA. Interleukin-18 and the pathogenesis of inflammatory diseases. Seminars in Nephrology. 27: 98-114. PMID 17336692 DOI: 10.1016/J.Semnephrol.2006.09.013 |
0.693 |
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| 2007 |
Krelin Y, Voronov E, Dotan S, Elkabets M, Reich E, Fogel M, Huszar M, Iwakura Y, Segal S, Dinarello CA, Apte RN. Interleukin-1β-driven inflammation promotes the development and invasiveness of chemical carcinogen-induced tumors Cancer Research. 67: 1062-1071. PMID 17283139 DOI: 10.1158/0008-5472.Can-06-2956 |
0.665 |
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| 2007 |
Larsen L, Tonnesen M, Ronn SG, Størling J, Jørgensen S, Mascagni P, Dinarello CA, Billestrup N, Mandrup-Poulsen T. Inhibition of histone deacetylases prevents cytokine-induced toxicity in beta cells. Diabetologia. 50: 779-89. PMID 17265033 DOI: 10.1007/S00125-006-0562-3 |
0.373 |
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| 2007 |
Sailer CA, Pott GB, Dinarello CA, Whinney SM, Forster JE, Larson-Duran JK, Landay A, Al-Harthi L, Schooley RT, Benson CA, Judson FN, Thompson M, Palella FJ, Shapiro L. Whole-blood interleukin-18 level during early HIV-1 infection is associated with reduced CXCR4 coreceptor expression and interferon- gamma levels. The Journal of Infectious Diseases. 195: 734-8. PMID 17262717 DOI: 10.1086/511435 |
0.596 |
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| 2007 |
Edelstein CL, Hoke TS, Somerset H, Fang W, Klein CL, Dinarello CA, Faubel S. Proximal tubules from caspase-1-deficient mice are protected against hypoxia-induced membrane injury. Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association. 22: 1052-61. PMID 17255124 DOI: 10.1093/NDT/GFL775 |
0.528 |
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| 2007 |
Kamari Y, Werman-Venkert R, Shaish A, Werman A, Harari A, Gonen A, Voronov E, Grosskopf I, Sharabi Y, Grossman E, Iwakura Y, Dinarello CA, Apte RN, Harats D. Differential role and tissue specificity of interleukin-1alpha gene expression in atherogenesis and lipid metabolism. Atherosclerosis. 195: 31-8. PMID 17173923 DOI: 10.1016/J.Atherosclerosis.2006.11.026 |
0.59 |
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| 2007 |
Nold-Petry CA, Nold MF, Bustamante A, Dinarello CA. 111 Knockout of the IL-18 Receptor Chain Enhances the Secretion of Pro-inflammatory Cytokines Cytokine. 39: 30-30. DOI: 10.1016/J.Cyto.2007.07.116 |
0.526 |
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| 2007 |
Nold MF, Nold-Petry CA, Pott GB, Bustamante A, Dinarello CA. 110 Endogenous IL-32 Suppresses HIV-1 Cytokine. 39: 30-30. DOI: 10.1016/J.Cyto.2007.07.115 |
0.445 |
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| 2007 |
Nelson EL, Nishimoto KP, Hou S, Dinarello CA. 107 Constitutive Expression of IL-32 Characterizes a Unique Subset of Human Dendritic Cells Receptive to the Venezuelan Equine Encephalitis Virus-Derived Replicon Vector Cytokine. 39: 29-29. DOI: 10.1016/J.Cyto.2007.07.112 |
0.456 |
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| 2006 |
Lewis EC, Dinarello CA. Responses of IL-18- and IL-18 receptor-deficient pancreatic islets with convergence of positive and negative signals for the IL-18 receptor. Proceedings of the National Academy of Sciences of the United States of America. 103: 16852-7. PMID 17075045 DOI: 10.1073/Pnas.0607917103 |
0.692 |
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| 2006 |
Dinarello CA, Kim S-. IL-32, a novel cytokine with a possible role in disease Annals of the Rheumatic Diseases. 65. PMID 17038476 DOI: 10.1136/Ard.2006.058511 |
0.585 |
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| 2006 |
Dinarello CA. The paradox of pro-inflammatory cytokines in cancer. Cancer and Metastasis Reviews. 25: 307-313. PMID 17029030 DOI: 10.1007/S10555-006-9000-8 |
0.627 |
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| 2006 |
Vidal-Vanaclocha F, Mendoza L, Telleria N, Salado C, Valcárcel M, Gallot N, Carrascal T, Egilegor E, Beaskoetxea J, Dinarello CA. Clinical and experimental approaches to the pathophysiology of interleukin-18 in cancer progression Cancer and Metastasis Reviews. 25: 417-434. PMID 17001512 DOI: 10.1007/S10555-006-9013-3 |
0.688 |
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| 2006 |
Edwards CK, Bendele AM, Reznikov LI, Fantuzzi G, Chlipala ES, Li L, Moldawer LL, Mountz JD, Li YY, Dinarello CA. Soluble human p55 and p75 tumor necrosis factor receptors reverse spontaneous arthritis in transgenic mice expressing transmembrane tumor necrosis factor alpha. Arthritis and Rheumatism. 54: 2872-85. PMID 16947419 DOI: 10.1002/Art.22077 |
0.494 |
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| 2006 |
Netea MG, Azam T, Ferwerda G, Girardin SE, Kim SH, Dinarello CA. Triggering receptor expressed on myeloid cells-1 (TREM-1) amplifies the signals induced by the NACHT-LRR (NLR) pattern recognition receptors. Journal of Leukocyte Biology. 80: 1454-61. PMID 16940328 DOI: 10.1189/Jlb.1205758 |
0.616 |
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| 2006 |
Netea MG, Azam T, Lewis EC, Joosten LA, Wang M, Langenberg D, Meng X, Chan ED, Yoon DY, Ottenhoff T, Kim SH, Dinarello CA. Mycobacterium tuberculosis induces interleukin-32 production through a caspase- 1/IL-18/interferon-gamma-dependent mechanism. Plos Medicine. 3: e277. PMID 16903774 DOI: 10.1371/Journal.Pmed.0030277 |
0.694 |
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| 2006 |
Abraham E, Nick JA, Azam T, Kim SH, Mira J, Svetkauskaite D, He Q, Zamora M, Murphy J, Park JS, Overdier K, Dinarello CA. Peripheral Blood Neutrophil Activation Patterns Are Associated with Pulmonary Inflammatory Responses to Lipopolysaccharide in Humans Journal of Immunology. 176: 7753-7760. PMID 16751423 DOI: 10.4049/Jimmunol.176.12.7753 |
0.531 |
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| 2006 |
Netea MG, Joosten LAB, Lewis E, Jensen DR, Voshol PJ, Kullberg BJ, Tack CJ, Van Krieken H, Kim SH, Stalenhoef AF, Van De Loo FA, Verschueren I, Pulawa L, Akira S, Eckel RH, ... Dinarello CA, et al. Deficiency of interleukin-18 in mice leads to hyperphagia, obesity and insulin resistance Nature Medicine. 12: 650-656. PMID 16732281 DOI: 10.1038/Nm1415 |
0.551 |
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| 2006 |
Dvorkin T, Song X, Argov S, White RM, Zoller M, Segal S, Dinarello CA, Voronov E, Apte RN. Immune phenomena involved in the in vivo regression of fibrosarcoma cells expressing cell-associated IL-1α Journal of Leukocyte Biology. 80: 96-106. PMID 16707560 DOI: 10.1189/Jlb.0905509 |
0.655 |
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| 2006 |
Carta S, Tassi S, Semino C, Fossati G, Mascagni P, Dinarello CA, Rubartelli A. Histone deacetylase inhibitors prevent exocytosis of interleukin-1beta-containing secretory lysosomes: role of microtubules. Blood. 108: 1618-26. PMID 16684958 DOI: 10.1182/Blood-2006-03-014126 |
0.645 |
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| 2006 |
Glauben R, Batra A, Fedke I, Zeitz M, Lehr HA, Leoni F, Mascagni P, Fantuzzi G, Dinarello CA, Siegmund B. Histone hyperacetylation is associated with amelioration of experimental colitis in mice. Journal of Immunology (Baltimore, Md. : 1950). 176: 5015-22. PMID 16585598 DOI: 10.4049/Jimmunol.176.8.5015 |
0.519 |
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| 2006 |
Morris AM, Sennello JA, Fayad RA, Eckel RH, Dinarello CA, Fantuzzi G. T cell-mediated hepatic inflammation modulates adiponectin levels in mice: role of tumor necrosis factor alpha. Metabolism: Clinical and Experimental. 55: 555-9. PMID 16546488 DOI: 10.1016/J.Metabol.2005.11.008 |
0.53 |
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| 2006 |
Joosten LAB, Netea MG, Kim S, Yoon D, Oppers-Walgreen B, Radstake TRD, Barrera P, Loo FAJvd, Dinarello CA, Berg WBvd. IL-32, a proinflammatory cytokine in rheumatoid arthritis. Proceedings of the National Academy of Sciences of the United States of America. 103: 3298-3303. PMID 16492735 DOI: 10.1073/Pnas.0511233103 |
0.687 |
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| 2006 |
Novick D, Rubinstein M, Azam T, Rabinkov A, Dinarello CA, Kim SH. Proteinase 3 is an IL-32 binding protein. Proceedings of the National Academy of Sciences of the United States of America. 103: 3316-21. PMID 16488976 DOI: 10.1073/Pnas.0511206103 |
0.687 |
|
| 2006 |
Dinarello CA. Interleukin 1 and interleukin 18 as mediators of inflammation and the aging process. The American Journal of Clinical Nutrition. 83. PMID 16470011 DOI: 10.1093/Ajcn/83.2.447S |
0.693 |
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| 2006 |
Dinarello CA. Interleukin-1beta. Critical Care Medicine. 33: S460-2. PMID 16340421 DOI: 10.1097/01.ccm.0000185500.11080.91 |
0.39 |
|
| 2006 |
Rodriguez RM, Abdullah R, Miller R, Barry L, Lungstras-Bufler K, Bufler P, Dinarello CA, Abraham E. A pilot study of cytokine levels and white blood cell counts in the diagnosis of necrotizing fasciitis. The American Journal of Emergency Medicine. 24: 58-61. PMID 16338511 DOI: 10.1016/J.Ajem.2005.02.028 |
0.656 |
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| 2006 |
Portnoy J, Pan T, Dinarello CA, Shannon JM, Westcott JY, Zhang L, Mason RJ. Alveolar type II cells inhibit fibroblast proliferation: role of IL-1alpha. American Journal of Physiology. Lung Cellular and Molecular Physiology. 290: L307-16. PMID 16169897 DOI: 10.1152/Ajplung.00102.2005 |
0.562 |
|
| 2006 |
Boraschi D, Dinarello CA. IL-18 in autoimmunity: review European Cytokine Network. 17: 224-252. DOI: 10.1684/Ecn.2006.0047 |
0.549 |
|
| 2006 |
Tan ZS, Seshadri S, Beiser A, Roubenoff R, Dinarello C, Harris T, Benjamin E, Au R, Kiel DP, Vasan RS, Wolf PA. P1-209: Relations of serum inflammatory markers and monocyte production of cytokines to the risk for Alzheimer's disease: The Framingham study Alzheimer's & Dementia. 2: S157-S157. DOI: 10.1016/J.Jalz.2006.05.586 |
0.313 |
|
| 2005 |
Dinarello CA, Kaplanski G. Interleukin-18 treatment options for inflammatory diseases. Expert Review of Clinical Immunology. 1: 619-632. PMID 20477603 DOI: 10.1586/1744666X.1.4.619 |
0.694 |
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| 2005 |
Leoni F, Fossati G, Lewis EC, Lee JK, Porro G, Pagani P, Modena D, Moras ML, Pozzi P, Reznikov LL, Siegmund B, Fantuzzi G, Dinarello CA, Mascagni P. The histone deacetylase inhibitor ITF2357 reduces production of pro-inflammatory cytokines in vitro and systemic inflammation in vivo. Molecular Medicine (Cambridge, Mass.). 11: 1-15. PMID 16557334 DOI: 10.2119/2006-00005.Dinarello |
0.686 |
|
| 2005 |
Song X, Krelin Y, Dvorkin T, Bjorkdahl O, Segal S, Dinarello CA, Voronov E, Apte RN. CD11b+/Gr-1+ Immature Myeloid Cells Mediate Suppression of T Cells in Mice Bearing Tumors of IL-1β-Secreting Cells Journal of Immunology. 175: 8200-8208. PMID 16339559 DOI: 10.4049/Jimmunol.175.12.8200 |
0.606 |
|
| 2005 |
Dinarello CA. An IL-1 Family Member Requires Caspase-1 Processing and Signals through the ST2 Receptor Immunity. 23: 461-462. PMID 16286013 DOI: 10.1016/J.Immuni.2005.10.004 |
0.651 |
|
| 2005 |
Netea MG, Azam T, Ferwerda G, Girardin SE, Walsh M, Park JS, Abraham E, Kim JM, Yoon DY, Dinarello CA, Kim SH. IL-32 synergizes with nucleotide oligomerization domain (NOD) 1 and NOD2 ligands for IL-1beta and IL-6 production through a caspase 1-dependent mechanism. Proceedings of the National Academy of Sciences of the United States of America. 102: 16309-14. PMID 16260731 DOI: 10.1073/Pnas.0508237102 |
0.7 |
|
| 2005 |
Lee KA, Cho KJ, Kim SH, Shim JH, Lim JS, Cho DH, Song MS, Dinarello CA, Yoon DY. IL-18 E42A mutant is resistant to the inhibitory effects of HPV-16 E6 and E7 oncogenes on the IL-18-mediated immune response. Cancer Letters. 229: 261-70. PMID 16125299 DOI: 10.1016/J.Canlet.2005.06.042 |
0.611 |
|
| 2005 |
Clarke JH, Cha JY, Walsh MD, Gamboni-Robertson F, Banerjee A, Reznikov LL, Dinarello CA, Harken AH, McCarter MD. Melanoma inhibits macrophage activation by suppressing toll-like receptor 4 signaling. Journal of the American College of Surgeons. 201: 418-25. PMID 16125076 DOI: 10.1016/J.Jamcollsurg.2005.04.035 |
0.519 |
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| 2005 |
Jones-Carson J, Fantuzzi G, Siegmund B, Dinarello C, Tracey KJ, Wang H, Fang FC, Vazquez-Torres A. Suppressor alphabeta T lymphocytes control innate resistance to endotoxic shock. The Journal of Infectious Diseases. 192: 1039-46. PMID 16107957 DOI: 10.1086/432727 |
0.527 |
|
| 2005 |
Lewis EC, Shapiro L, Bowers OJ, Dinarello CA. Alpha1-antitrypsin monotherapy prolongs islet allograft survival in mice. Proceedings of the National Academy of Sciences of the United States of America. 102: 12153-8. PMID 16093309 DOI: 10.1073/Pnas.0505579102 |
0.541 |
|
| 2005 |
Fayad R, Sennello JA, Kim S, Pini M, Dinarello CA, Fantuzzi G. Induction of thymocyte apoptosis by systemic administration of concanavalin A in mice: role of TNF‐α, IFN‐γ and glucocorticoids European Journal of Immunology. 35: 2304-2312. PMID 16047339 DOI: 10.1002/Eji.200526062 |
0.526 |
|
| 2005 |
Mazodier K, Marin V, Novick D, Farnarier C, Robitail S, Schleinitz N, Veit V, Paul P, Rubinstein M, Dinarello CA, Harlé JR, Kaplanski G. Severe imbalance of IL-18/IL-18BP in patients with secondary hemophagocytic syndrome. Blood. 106: 3483-9. PMID 16020503 DOI: 10.1182/Blood-2005-05-1980 |
0.689 |
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| 2005 |
Dinarello CA. The many worlds of reducing interleukin-1. Arthritis & Rheumatism. 52: 1960-1967. PMID 15986340 DOI: 10.1002/Art.21107 |
0.575 |
|
| 2005 |
Stuyt RJ, Netea MG, Verschueren I, Dinarello CA, Kullberg BJ, van der Meer JW. Interleukin-18 does not modulate the acute-phase response. Journal of Endotoxin Research. 11: 85-8. PMID 15949134 DOI: 10.1179/096805105X35170 |
0.629 |
|
| 2005 |
Numerof RP, Dinarello CA, Asadullah K. Cytokines as potential therapeutic targets for inflammatory skin diseases. European Cytokine Network. 16: 101-3. PMID 15941680 |
0.554 |
|
| 2005 |
Fitzgerald AA, Leclercq SA, Yan A, Homik JE, Dinarello CA. Rapid responses to anakinra in patients with refractory adult-onset Still's disease. Arthritis and Rheumatism. 52: 1794-803. PMID 15934079 DOI: 10.1002/Art.21061 |
0.539 |
|
| 2005 |
Dinarello CA. Blocking IL-1 in systemic inflammation Journal of Experimental Medicine. 201: 1355-1359. PMID 15867089 DOI: 10.1084/Jem.20050640 |
0.673 |
|
| 2005 |
Ludwiczek O, Kaser A, Novick D, Dinarello CA, Rubinstein M, Tilg H. Elevated systemic levels of free interleukin-18 (IL-18) in patients with Crohn's disease. European Cytokine Network. 16: 27-33. PMID 15809203 |
0.639 |
|
| 2005 |
Dinarello CA. Differences between anti-tumor necrosis factor-alpha monoclonal antibodies and soluble TNF receptors in host defense impairment. The Journal of Rheumatology. Supplement. 74: 40-7. PMID 15742464 |
0.419 |
|
| 2005 |
Kumar A, Zanotti S, Bunnell G, Habet K, Añel R, Neumann A, Cheang M, Dinarello CA, Cutler D, Parrillo JE. Interleukin-10 blunts the human inflammatory response to lipopolysaccharide without affecting the cardiovascular response. Critical Care Medicine. 33: 331-40. PMID 15699836 DOI: 10.1097/01.Ccm.0000152229.69180.2 |
0.598 |
|
| 2005 |
Sennello JA, Fayad R, Morris AM, Eckel RH, Asilmaz E, Montez J, Friedman JM, Dinarello CA, Fantuzzi G. Regulation of T cell-mediated hepatic inflammation by adiponectin and leptin. Endocrinology. 146: 2157-64. PMID 15677756 DOI: 10.1210/En.2004-1572 |
0.508 |
|
| 2005 |
Kim SH, Han SY, Azam T, Yoon DY, Dinarello CA. Interleukin-32: a cytokine and inducer of TNFalpha. Immunity. 22: 131-42. PMID 15664165 DOI: 10.1016/J.Immuni.2004.12.003 |
0.703 |
|
| 2005 |
Wang W, Faubel S, Ljubanovic D, Mitra A, Falk SA, Kim J, Tao Y, Soloviev A, Reznikov LL, Dinarello CA, Schrier RW, Edelstein CL. Endotoxemic acute renal failure is attenuated in caspase-1-deficient mice American Journal of Physiology - Renal Physiology. 288. PMID 15644489 DOI: 10.1152/ajprenal.00130.2004 |
0.613 |
|
| 2005 |
Faubel S, Ljubanovic D, Reznikov L, Somerset H, Dinarello CA, Edelstein CL. Caspase-1-deficient mice are protected against cisplatin-induced apoptosis and acute tubular necrosis. Kidney International. 66: 2202-13. PMID 15569309 DOI: 10.1111/J.1523-1755.2004.66010.X |
0.379 |
|
| 2005 |
Dinarello CA. Infection, fever, and exogenous and endogenous pyrogens: some concepts have changed. Journal of Endotoxin Research. 10: 201-22. PMID 15373964 DOI: 10.1179/096805104225006129 |
0.623 |
|
| 2005 |
Lavi G, Dinarello CA, Apte RN, Cohen S. Sustained release of IL‐1Ra from biodegradable microspheres prolongs its IL‐1‐neutralizing effects Israel Journal of Chemistry. 45: 457-464. DOI: 10.1560/Dybg-Twdv-J8Pf-7W9T |
0.502 |
|
| 2005 |
Reddy P, Maeda Y, Duran-Struuck R, Krijanovski O, Dinarello C, Ferrara JL. Histone Deacetylase Inhibitors Induce Immuno-Dominant Suppression of Dendritic Cells. Blood. 106: 456-456. DOI: 10.1182/Blood.V106.11.456.456 |
0.371 |
|
| 2005 |
Stuyt RJL, Netea MG, Verschueren I, Dinarello CA, Kullberg BJ, Meer JWMvd. Interleukin-18 does not modulate the acute-phase response: Journal of Endotoxin Research. 11: 85-88. DOI: 10.1177/09680519050110020301 |
0.547 |
|
| 2005 |
Numerof RP, Dinarello CA, Asadullah K. Cytokines as potential therapeutic targets for inflammatory skin diseases European Cytokine Network. 16: 101-103. DOI: 10.1007/3-540-37673-9 |
0.456 |
|
| 2004 |
Lee HG, Kim H, Oh WK, Yu KA, Choe YK, Ahn JS, Kim DS, Kim SH, Dinarello CA, Kim K, Yoon DY. Tetramethoxy Hydroxyflavone p7F Downregulates Inflammatory Mediators via the Inhibition of Nuclear Factor κB Annals of the New York Academy of Sciences. 1030: 555-568. PMID 15659838 DOI: 10.1196/Annals.1329.065 |
0.52 |
|
| 2004 |
Ludwiczek O, Vannier E, Borggraefe I, Kaser A, Siegmund B, Dinarello CA, Tilg H. Imbalance between interleukin-1 agonists and antagonists: relationship to severity of inflammatory bowel disease. Clinical and Experimental Immunology. 138: 323-329. PMID 15498044 DOI: 10.1111/J.1365-2249.2004.02599.X |
0.546 |
|
| 2004 |
Lungstras-Bufler K, Bufler P, Abdullah R, Rutherford C, Endres S, Abraham E, Dinarello CA, Rodriguez RM. High cytokine levels at admission are associated with fatal outcome in patients with necrotizing fasciitis. European Cytokine Network. 15: 135-8. PMID 15319173 |
0.612 |
|
| 2004 |
Siegmund B, Sennello JA, Lehr HA, Senaldi G, Dinarello CA, Fantuzzi G. Frontline: Interferon regulatory factor-1 as a protective gene in intestinal inflammation: role of TCR γ δ T cells and interleukin-18-binding protein European Journal of Immunology. 34: 2356-2364. PMID 15307168 DOI: 10.1002/Eji.200425124 |
0.645 |
|
| 2004 |
Dinarello CA. Therapeutic strategies to reduce IL-1 activity in treating local and systemic inflammation. Current Opinion in Pharmacology. 4: 378-385. PMID 15251132 DOI: 10.1016/J.Coph.2004.03.010 |
0.685 |
|
| 2004 |
Netea MG, Kullberg BJ, Jacobs LEH, Verver-Jansen TJG, Ven-Jongekrijg Jvd, Galama JMD, Stalenhoef AFH, Dinarello CA, Meer JWMVd. Chlamydia pneumoniae stimulates IFN-gamma synthesis through MyD88-dependent, TLR2- and TLR4-independent induction of IL-18 release. Journal of Immunology. 173: 1477-1482. PMID 15240744 DOI: 10.4049/Jimmunol.173.2.1477 |
0.677 |
|
| 2004 |
Reznikov LL, Waksman J, Azam T, Kim SH, Bufler P, Niwa T, Werman A, Zhang X, Pischetsrieder M, Shaldon S, Dinarello CA. Effect of advanced glycation end products on endotoxin-induced TNF-alpha, IL-1beta and IL-8 in human peripheral blood mononuclear cells. Clinical Nephrology. 61: 324-36. PMID 15182127 DOI: 10.5414/CNP61324 |
0.306 |
|
| 2004 |
Dinarello CA. Interleukin-18 and the treatment of rheumatoid arthritis. Rheumatic Diseases Clinics of North America. 30: 417-434. PMID 15172050 DOI: 10.1016/J.Rdc.2004.02.001 |
0.687 |
|
| 2004 |
Lee JK, Kim SH, Lewis EC, Azam T, Reznikov LL, Dinarello CA. Differences in signaling pathways by IL-1beta and IL-18. Proceedings of the National Academy of Sciences of the United States of America. 101: 8815-20. PMID 15161979 DOI: 10.1073/Pnas.0402800101 |
0.695 |
|
| 2004 |
Schottelius AJG, Moldawer LL, Dinarello CA, Asadullah K, Sterry W, Edwards CK. Biology of tumor necrosis factor-alpha- implications for psoriasis. Experimental Dermatology. 13: 193-222. PMID 15086336 DOI: 10.1111/J.0906-6705.2004.00205.X |
0.5 |
|
| 2004 |
Bufler P, Gamboni-Robertson F, Azam T, Kim S, Dinarello CA. Interleukin-1 homologues IL-1F7b and IL-18 contain functional mRNA instability elements within the coding region responsive to lipopolysaccharide Biochemical Journal. 381: 503-510. PMID 15046617 DOI: 10.1042/Bj20040217 |
0.684 |
|
| 2004 |
Dinarello CA. Unraveling the NALP-3/IL-1β Inflammasome: A Big Lesson from a Small Mutation Immunity. 20: 243-244. PMID 15030767 DOI: 10.1016/S1074-7613(04)00055-X |
0.642 |
|
| 2004 |
Reddy P, Maeda Y, Hotary K, Liu C, Reznikov LL, Dinarello CA, Ferrara JL. Histone deacetylase inhibitor suberoylanilide hydroxamic acid reduces acute graft-versus-host disease and preserves graft-versus-leukemia effect. Proceedings of the National Academy of Sciences of the United States of America. 101: 3921-6. PMID 15001702 DOI: 10.1073/Pnas.0400380101 |
0.499 |
|
| 2004 |
Werman A, Werman-Venkert R, White R, Lee JK, Werman B, Krelin Y, Voronov E, Dinarello CA, Apte RN. The precursor form of IL-1alpha is an intracrine proinflammatory activator of transcription. Proceedings of the National Academy of Sciences of the United States of America. 101: 2434-9. PMID 14983027 DOI: 10.1073/Pnas.0308705101 |
0.66 |
|
| 2004 |
Park JW, Taube C, Swasey C, Kodama T, Joetham A, Balhorn A, Takeda K, Miyahara N, Allen CB, Dakhama A, Kim SH, Dinarello CA, Gelfand EW. Interleukin-1 receptor antagonist attenuates airway hyperresponsiveness following exposure to ozone. American Journal of Respiratory Cell and Molecular Biology. 30: 830-6. PMID 14754758 DOI: 10.1165/Rcmb.2003-0373Oc |
0.612 |
|
| 2004 |
Wang M, Sankula R, Tsai BM, Meldrum KK, Turrentine M, March KL, Brown JW, Dinarello CA, Meldrum DR. P38 MAPK mediates myocardial proinflammatory cytokine production and endotoxin-induced contractile suppression. Shock (Augusta, Ga.). 21: 170-4. PMID 14752292 DOI: 10.1097/01.Shk.0000110623.20647.Aa |
0.601 |
|
| 2004 |
Taube C, Nick JA, Siegmund B, Duez C, Takeda K, Rha Y, Park J, Joetham A, Poch K, Dakhama A, Dinarello CA, Gelfand EW. Inhibition of early airway neutrophilia does not affect development of airway hyperresponsiveness American Journal of Respiratory Cell and Molecular Biology. 30: 837-843. PMID 14742296 DOI: 10.1165/Rcmb.2003-0395Oc |
0.672 |
|
| 2004 |
Rijneveld AW, Florquin S, Speelman P, Edwards CK, Dinarello CA, van der Poll T. Interleukin-1 receptor antagonist transiently impairs antibacterial defense but not survival in murine pneumococcal pneumonia. European Cytokine Network. 14: 242-5. PMID 14715417 |
0.633 |
|
| 2004 |
Bar D, Apte RN, Voronov E, Dinarello CA, Cohen S. A continuous delivery system of IL-1 receptor antagonist reduces angiogenesis and inhibits tumor development. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 18: 161-3. PMID 14597552 DOI: 10.1096/Fj.03-0483Fje |
0.663 |
|
| 2004 |
Dinarello CA. Review: Infection, fever, and exogenous and endogenous pyrogens: some concepts have changed Journal of Endotoxin Research. 10: 201-222. DOI: 10.1177/09680519040100040301 |
0.454 |
|
| 2004 |
DINARELLO CA. THE ROLE OF IL-18 IN SEPSIS Shock. 21: 124. DOI: 10.1097/00024382-200403001-00494 |
0.46 |
|
| 2003 |
Nolsøe RL, Pociot F, Novick D, Rubinstein M, Kim SH, Dinarello CA, Mandrup-Poulsen T. Mutation scan of a type 1 diabetes candidate gene: the human interleukin-18 binding protein gene. Annals of the New York Academy of Sciences. 1005: 332-9. PMID 14679086 DOI: 10.1196/Annals.1288.053 |
0.574 |
|
| 2003 |
Azam T, Novick D, Bufler P, Yoon DY, Rubinstein M, Dinarello CA, Kim SH. Identification of a critical Ig-like domain in IL-18 receptor alpha and characterization of a functional IL-18 receptor complex. Journal of Immunology (Baltimore, Md. : 1950). 171: 6574-80. PMID 14662859 DOI: 10.4049/Jimmunol.171.12.6574 |
0.676 |
|
| 2003 |
Song X, Voronov E, Dvorkin T, Fima E, Cagnano E, Benharroch D, Shendler Y, Bjorkdahl O, Segal S, Dinarello CA, Apte RN. Differential Effects of IL-1α and IL-1β on Tumorigenicity Patterns and Invasiveness Journal of Immunology. 171: 6448-6456. PMID 14662844 DOI: 10.4049/Jimmunol.171.12.6448 |
0.639 |
|
| 2003 |
Lonnemann G, Novick D, Rubinstein M, Dinarello CA. Interleukin-18, interleukin-18 binding protein and impaired production of interferon-gamma in chronic renal failure. Clinical Nephrology. 60: 327-34. PMID 14640238 DOI: 10.5414/CNP60327 |
0.366 |
|
| 2003 |
Stuyt RJL, Netea MG, Geijtenbeek TBH, Kullberg BJ, Dinarello CA, Meer JWMVD. Selective regulation of intercellular adhesion molecule-1 expression by interleukin-18 and interleukin-12 on human monocytes Immunology. 110: 329-334. PMID 14632660 DOI: 10.1046/J.1365-2567.2003.01747.X |
0.676 |
|
| 2003 |
Bossù P, Neumann D, Giudice ED, Ciaramella A, Gloaguen I, Fantuzzi G, Dinarello CA, Carlo ED, Musiani P, Meroni PL, Caselli G, Ruggiero P, Boraschi D. IL-18 cDNA vaccination protects mice from spontaneous lupus-like autoimmune disease Proceedings of the National Academy of Sciences of the United States of America. 100: 14181-14186. PMID 14615579 DOI: 10.1073/Pnas.2336094100 |
0.668 |
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