W Davis Parker - Publications

Affiliations: 
Neurology University of Virginia School of Medicine, Charlottesville, VA, United States 

36 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2008 Parker WD, Parks JK, Swerdlow RH. Complex I deficiency in Parkinson's disease frontal cortex. Brain Research. 1189: 215-8. PMID 18061150 DOI: 10.1016/J.Brainres.2007.10.061  0.321
2008 McAllister J, Ghosh S, Berry D, Park M, Sadeghi S, Wang KX, Parker WD, Swerdlow RH. Effects of memantine on mitochondrial function. Biochemical Pharmacology. 75: 956-64. PMID 18053965 DOI: 10.1016/J.Bcp.2007.10.019  0.364
2005 Smigrodzki R, Goertzel B, Pennachin C, Coelho L, Prosdocimi F, Parker WD. Genetic algorithm for analysis of mutations in Parkinson's disease. Artificial Intelligence in Medicine. 35: 227-41. PMID 16207526 DOI: 10.1016/J.Artmed.2004.11.006  0.337
2005 Parker WD, Parks JK. Mitochondrial ND5 mutations in idiopathic Parkinson's disease. Biochemical and Biophysical Research Communications. 326: 667-9. PMID 15596151 DOI: 10.1016/J.Bbrc.2004.11.093  0.358
2004 Smigrodzki R, Parks J, Parker WD. High frequency of mitochondrial complex I mutations in Parkinson's disease and aging. Neurobiology of Aging. 25: 1273-81. PMID 15465623 DOI: 10.1016/J.Neurobiolaging.2004.02.020  0.342
2004 Trimmer PA, Borland MK, Keeney PM, Bennett JP, Parker WD. Parkinson's disease transgenic mitochondrial cybrids generate Lewy inclusion bodies. Journal of Neurochemistry. 88: 800-12. PMID 14756800 DOI: 10.1046/J.1471-4159.2003.02168.X  0.336
2004 Trimmer PA, Keeney PM, Borland MK, Simon FA, Almeida J, Swerdlow RH, Parks JP, Parker WD, Bennett JP. Mitochondrial abnormalities in cybrid cell models of sporadic Alzheimer's disease worsen with passage in culture. Neurobiology of Disease. 15: 29-39. PMID 14751768 DOI: 10.1016/J.Nbd.2003.09.011  0.405
2001 Swerdlow RH, Parks JK, Cassarino DS, Binder DR, Bennett JP, Di Iorio G, Golbe LI, Parker WD. Biochemical analysis of cybrids expressing mitochondrial DNA from Contursi kindred Parkinson's subjects. Experimental Neurology. 169: 479-85. PMID 11358461 DOI: 10.1006/Exnr.2001.7674  0.348
2001 Parks JK, Smith TS, Trimmer PA, Bennett JP, Parker WD. Neurotoxic Abeta peptides increase oxidative stress in vivo through NMDA-receptor and nitric-oxide-synthase mechanisms, and inhibit complex IV activity and induce a mitochondrial permeability transition in vitro. Journal of Neurochemistry. 76: 1050-6. PMID 11181824 DOI: 10.1046/J.1471-4159.2001.00112.X  0.352
2001 Albers DS, Swerdlow RH, Manfredi G, Gajewski C, Yang L, Parker WD, Beal MF. Further evidence for mitochondrial dysfunction in progressive supranuclear palsy. Experimental Neurology. 168: 196-8. PMID 11170735 DOI: 10.1006/Exnr.2000.7607  0.399
2000 Swerdlow RH, Parks JK, Pattee G, Parker WD. Role of mitochondria in amyotrophic lateral sclerosis. Amyotrophic Lateral Sclerosis and Other Motor Neuron Disorders : Official Publication of the World Federation of Neurology, Research Group On Motor Neuron Diseases. 1: 185-90. PMID 11464951 DOI: 10.1080/14660820050515179  0.345
2000 Veech GA, Dennis J, Keeney PM, Fall CP, Swerdlow RH, Parker WD, Bennett JP. Disrupted mitochondrial electron transport function increases expression of anti-apoptotic bcl-2 and bcl-X(L) proteins in SH-SY5Y neuroblastoma and in Parkinson disease cybrid cells through oxidative stress. Journal of Neuroscience Research. 61: 693-700. PMID 10972966 DOI: 10.1002/1097-4547(20000915)61:6<693::Aid-Jnr13>3.0.Co;2-4  0.334
2000 Cassarino DS, Halvorsen EM, Swerdlow RH, Abramova NN, Parker WD, Sturgill TW, Bennett JP. Interaction among mitochondria, mitogen-activated protein kinases, and nuclear factor-kappaB in cellular models of Parkinson's disease. Journal of Neurochemistry. 74: 1384-92. PMID 10737593 DOI: 10.1046/J.1471-4159.2000.0741384.X  0.332
2000 Trimmer PA, Swerdlow RH, Parks JK, Keeney P, Bennett JP, Miller SW, Davis RE, Parker WD. Abnormal mitochondrial morphology in sporadic Parkinson's and Alzheimer's disease cybrid cell lines. Experimental Neurology. 162: 37-50. PMID 10716887 DOI: 10.1006/Exnr.2000.7333  0.399
2000 Khan SM, Cassarino DS, Abramova NN, Keeney PM, Borland MK, Trimmer PA, Krebs CT, Bennett JC, Parks JK, Swerdlow RH, Parker WD, Bennett JP. Alzheimer's disease cybrids replicate ?-amyloid abnormalities through cell death pathways Annals of Neurology. 48: 148-155. DOI: 10.1002/1531-8249(200008)48:2<148::Aid-Ana3>3.0.Co;2-7  0.302
1999 Ghosh SS, Swerdlow RH, Miller SW, Sheeman B, Parker WD, Davis RE. Use of cytoplasmic hybrid cell lines for elucidating the role of mitochondrial dysfunction in Alzheimer's disease and Parkinson's disease. Annals of the New York Academy of Sciences. 893: 176-91. PMID 10672237 DOI: 10.1111/J.1749-6632.1999.Tb07825.X  0.388
1999 Caldwell SH, Swerdlow RH, Khan EM, Iezzoni JC, Hespenheide EE, Parks JK, Parker WD. Mitochondrial abnormalities in non-alcoholic steatohepatitis Journal of Hepatology. 31: 430-434. PMID 10488700 DOI: 10.1016/S0168-8278(99)80033-6  0.333
1999 Swerdlow RH, Parks JK, Cassarino DS, Shilling AT, Bennett JP, Harrison MB, Parker WD. Characterization of cybrid cell lines containing mtDNA from Huntington's disease patients. Biochemical and Biophysical Research Communications. 261: 701-4. PMID 10441489 DOI: 10.1006/Bbrc.1999.1095  0.391
1999 Cassarino DS, Parks JK, Parker WD, Bennett JP. The parkinsonian neurotoxin MPP+ opens the mitochondrial permeability transition pore and releases cytochrome c in isolated mitochondria via an oxidative mechanism. Biochimica Et Biophysica Acta. 1453: 49-62. PMID 9989245 DOI: 10.1016/S0925-4439(98)00083-0  0.356
1999 Swerdlow RH, Parker WD. Mitochondrial pathology in Parkinson's disease and implications for therapeutic intervention Drug Development Research. 46: 44-50. DOI: 10.1002/(Sici)1098-2299(199901)46:1<44::Aid-Ddr7>3.0.Co;2-6  0.405
1998 Swerdlow RH, Parks JK, Davis JN, Cassarino DS, Trimmer PA, Currie LJ, Dougherty J, Bridges WS, Bennett JP, Wooten GF, Parker WD. Matrilineal inheritance of complex I dysfunction in a multigenerational Parkinson's disease family. Annals of Neurology. 44: 873-81. PMID 9851431 DOI: 10.1002/Ana.410440605  0.363
1998 Swerdlow RH, Parks JK, Cassarino DS, Trimmer PA, Miller SW, Maguire DJ, Sheehan JP, Maguire RS, Pattee G, Juel VC, Phillips LH, Tuttle JB, Bennett JP, Davis RE, Parker WD. Mitochondria in sporadic amyotrophic lateral sclerosis. Experimental Neurology. 153: 135-42. PMID 9743575 DOI: 10.1006/Exnr.1998.6866  0.35
1998 Cassarino DS, Swerdlow RH, Parks JK, Parker WD, Bennett JP. Cyclosporin A increases resting mitochondrial membrane potential in SY5Y cells and reverses the depressed mitochondrial membrane potential of Alzheimer's disease cybrids. Biochemical and Biophysical Research Communications. 248: 168-73. PMID 9675105 DOI: 10.1006/Bbrc.1998.8866  0.385
1998 Davis JN, Parker WD. Evidence that two reports of mtDNA cytochrome c oxidase 'Mutations' in Alzheimer's disease are based on nDNA pseudogenes of recent evolutionary origin Biochemical and Biophysical Research Communications. 244: 877-883. PMID 9535760 DOI: 10.1006/Bbrc.1998.8353  0.351
1998 Parker WD, Swerdlow RH. Mitochondrial dysfunction in idiopathic Parkinson disease. American Journal of Human Genetics. 62: 758-62. PMID 9529370 DOI: 10.1086/301812  0.388
1997 Cassarino DS, Fall CP, Swerdlow RH, Smith TS, Halvorsen EM, Miller SW, Parks JP, Parker WD, Bennett JP. Elevated reactive oxygen species and antioxidant enzyme activities in animal and cellular models of Parkinson's disease. Biochimica Et Biophysica Acta. 1362: 77-86. PMID 9434102 DOI: 10.1016/S0925-4439(97)00070-7  0.371
1997 Sheehan JP, Swerdlow RH, Miller SW, Davis RE, Parks JK, Parker WD, Tuttle JB. Calcium homeostasis and reactive oxygen species production in cells transformed by mitochondria from individuals with sporadic Alzheimer's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 4612-22. PMID 9169522 DOI: 10.1523/Jneurosci.17-12-04612.1997  0.363
1997 Davis RE, Miller S, Herrnstadt C, Ghosh SS, Fahy E, Shinobu LA, Galasko D, Thal LJ, Beal MF, Howell N, Parker WD. Mutations in mitochondrial cytochrome c oxidase genes segregate with late-onset Alzheimer disease. Proceedings of the National Academy of Sciences of the United States of America. 94: 4526-31. PMID 9114023 DOI: 10.1073/Pnas.94.9.4526  0.359
1997 Wooten GF, Currie LJ, Bennett JP, Harrison MB, Trugman JM, Parker WD. Maternal inheritance in Parkinson's disease. Annals of Neurology. 41: 265-8. PMID 9029076 DOI: 10.1002/Ana.410410218  0.309
1996 Miller SW, Trimmer PA, Parker WD, Davis RE. Creation and characterization of mitochondrial DNA-depleted cell lines with "neuronal-like" properties. Journal of Neurochemistry. 67: 1897-907. PMID 8863494 DOI: 10.1046/J.1471-4159.1996.67051897.X  0.377
1985 Haas R, Parker WD, Stumpf D, Eguren LA. Salicylate-induced loose coupling: protonmotive force measurements. Biochemical Pharmacology. 34: 900-2. PMID 3977963 DOI: 10.1016/0006-2952(85)90774-9  0.553
1985 Stumpf DA, Parker WD, Angelini C. Carnitine deficiency, organic acidemias, and Reye's syndrome. Neurology. 35: 1041-5. PMID 3892364 DOI: 10.1212/Wnl.35.7.1041  0.606
1984 Parker WD, Haas R, Stumpf DA, Parks J, Eguren LA, Jackson C. Brain mitochondrial metabolism in experimental thiamine deficiency. Neurology. 34: 1477-81. PMID 6493495 DOI: 10.1212/Wnl.34.11.1477  0.668
1983 Parker WD, Haas R, Stumpf DA, Eguren LA. Effects of octanoate on rat brain and liver mitochondria. Neurology. 33: 1374-7. PMID 6684238 DOI: 10.1212/Wnl.33.10.1374  0.66
1983 Stumpf DA, Parks JK, Parker WD. Friedreich's disease: IV. Reduced mitochondrial malic enzyme activity in heterozygotes. Neurology. 33: 780-3. PMID 6682522 DOI: 10.1212/Wnl.33.6.780  0.629
1983 Stumpf DA, Parker WD, Haas R. Carnitine deficiency with valproate therapy. The Journal of Pediatrics. 103: 175-6. PMID 6408234 DOI: 10.1016/S0022-3476(83)80831-2  0.557
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