Thomas Wishart - Publications

Affiliations: 
University of Edinburgh, Edinburgh, Scotland, United Kingdom 

58 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Arrázola MS, Lira M, Véliz-Valverde F, Quiroz G, Iqbal S, Eaton SL, Lamont DJ, Huerta H, Ureta G, Bernales S, Cárdenas JC, Cerpa W, Wishart TM, Court FA. Necroptosis inhibition counteracts neurodegeneration, memory decline, and key hallmarks of aging, promoting brain rejuvenation. Aging Cell. e13814. PMID 36973898 DOI: 10.1111/acel.13814  0.623
2022 Kline RA, Lößlein L, Kurian D, Aguilar Martí J, Eaton SL, Court FA, Gillingwater TH, Wishart TM. An Optimized Comparative Proteomic Approach as a Tool in Neurodegenerative Disease Research. Cells. 11. PMID 36078061 DOI: 10.3390/cells11172653  0.678
2022 Ledahawsky LM, Eirini Terzenidou M, Edwards R, Kline RA, Graham LC, Eaton SL, van der Hoorn D, Chaytow H, Huang YT, Groen EJN, Motyl AAL, Lamont DJ, Tokatlidis K, Wishart TM, Gillingwater TH. The mitochondrial protein Sideroflexin 3 (SFXN3) influences neurodegeneration pathways in vivo. The Febs Journal. PMID 35092170 DOI: 10.1111/febs.16377  0.637
2021 Graham LC, Kline RA, Lamont DJ, Gillingwater TH, Mabbott NA, Skehel PA, Wishart TM. Temporal Profiling of the Cortical Synaptic Mitochondrial Proteome Identifies Ageing Associated Regulators of Stability. Cells. 10. PMID 34943911 DOI: 10.3390/cells10123403  0.565
2021 Roesl C, Evans ER, Dissanayake KN, Boczonadi V, Jones RA, Jordan GR, Ledahawsky L, Allen GCC, Scott M, Thomson A, Wishart TM, Hughes DI, Mead RJ, Shone CC, Slater CR, et al. Confocal Endomicroscopy of Neuromuscular Junctions Stained with Physiologically Inert Protein Fragments of Tetanus Toxin. Biomolecules. 11. PMID 34680132 DOI: 10.3390/biom11101499  0.768
2021 Deguise MO, Pileggi C, De Repentigny Y, Beauvais A, Tierney A, Chehade L, Michaud J, Llavero-Hurtado M, Lamont D, Atrih A, Wishart TM, Gillingwater TH, Schneider BL, Harper ME, Parson SH, et al. SMN depleted mice offer a robust and rapid onset model of non-alcoholic fatty liver disease. Cellular and Molecular Gastroenterology and Hepatology. PMID 33545428 DOI: 10.1016/j.jcmgh.2021.01.019  0.694
2021 Graham LC, Kline RA, Lamont DJ, Gillingwater TH, Mabbott NA, Skehel PA, Wishart TM. Temporal Profiling of the Cortical Synaptic Mitochondrial Proteome Identifies Ageing Associated Regulators of Stability Cells. 10: 3403. DOI: 10.3390/cells10123403  0.565
2020 Lemaitre D, Hurtado ML, De Gregorio C, Oñate M, Martínez G, Catenaccio A, Wishart TM, Court FA. Collateral Sprouting of Peripheral Sensory Neurons Exhibits a Unique Transcriptomic Profile. Molecular Neurobiology. PMID 32696431 DOI: 10.1007/s12035-020-01986-3  0.647
2020 Motyl AAL, Faller KME, Groen EJN, Kline RA, Eaton SL, Ledahawsky LM, Chaytow H, Lamont DJ, Wishart TM, Huang YT, Gillingwater TH. Pre-natal manifestation of systemic developmental abnormalities in spinal muscular atrophy. Human Molecular Genetics. PMID 32644120 DOI: 10.1093/hmg/ddaa146  0.587
2020 Boehm I, Alhindi A, Leite AS, Logie C, Gibbs A, Murray O, Farrukh R, Pirie R, Proudfoot C, Clutton R, Wishart TM, Jones RA, Gillingwater TH. Comparative anatomy of the mammalian neuromuscular junction. Journal of Anatomy. PMID 32573802 DOI: 10.1111/joa.13260  0.566
2019 Boehm I, Miller J, Wishart TM, Wigmore SJ, Skipworth RJ, Jones RA, Gillingwater TH. Neuromuscular junctions are stable in patients with cancer cachexia. The Journal of Clinical Investigation. PMID 31794435 DOI: 10.1172/JCI128411  0.548
2019 Kline RA, Dissanayake KN, Hurtado ML, Martínez NW, Ahl A, Mole AJ, Lamont DJ, Court FA, Ribchester RR, Wishart TM, Murray LM. Altered mitochondrial bioenergetics are responsible for the delay in Wallerian degeneration observed in neonatal mice. Neurobiology of Disease. 104496. PMID 31176719 DOI: 10.1016/J.Nbd.2019.104496  0.785
2019 Graham LC, Naldrett MJ, Kohama SG, Smith C, Lamont DJ, McColl BW, Gillingwater TH, Skehel P, Urbanski HF, Wishart TM. Regional Molecular Mapping of Primate Synapses during Normal Healthy Aging. Cell Reports. 27: 1018-1026.e4. PMID 31018120 DOI: 10.1016/J.Celrep.2019.03.096  0.56
2019 Boehm I, Miller J, Wishart T, Wigmore S, Jones R, Skipworth R, Gillingwater T. SUN-LB665: Stability of the Neuromuscular Junction in Cancer Cachexia Clinical Nutrition. 38: S306. DOI: 10.1016/S0261-5614(19)32631-7  0.451
2018 Shorrock HK, van der Hoorn D, Boyd PJ, Llavero Hurtado M, Lamont DJ, Wirth B, Sleigh JN, Schiavo G, Wishart TM, Groen EJN, Gillingwater TH. UBA1/GARS-dependent pathways drive sensory-motor connectivity defects in spinal muscular atrophy. Brain : a Journal of Neurology. 141: 2878-2894. PMID 30239612 DOI: 10.1093/Brain/Awy237  0.581
2017 Jones RA, Harrison C, Eaton SL, Llavero Hurtado M, Graham LC, Alkhammash L, Oladiran OA, Gale A, Lamont DJ, Simpson H, Simmen MW, Soeller C, Wishart TM, Gillingwater TH. Cellular and Molecular Anatomy of the Human Neuromuscular Junction. Cell Reports. 21: 2348-2356. PMID 29186674 DOI: 10.1016/j.celrep.2017.11.008  0.612
2017 Catenaccio A, Llavero Hurtado M, Diaz P, Lamont DJ, Wishart TM, Court FA. Molecular analysis of axonal-intrinsic and glial-associated co-regulation of axon degeneration. Cell Death & Disease. 8: e3166. PMID 29120410 DOI: 10.1038/cddis.2017.489  0.615
2017 Graham LC, Eaton SL, Brunton PJ, Atrih A, Smith C, Lamont DJ, Gillingwater TH, Pennetta G, Skehel P, Wishart TM. Proteomic profiling of neuronal mitochondria reveals modulators of synaptic architecture. Molecular Neurodegeneration. 12: 77. PMID 29078798 DOI: 10.1186/S13024-017-0221-9  0.608
2017 Llavero Hurtado M, Fuller HR, Wong AMS, Eaton SL, Gillingwater TH, Pennetta G, Cooper JD, Wishart TM. Proteomic mapping of differentially vulnerable pre-synaptic populations identifies regulators of neuronal stability in vivo. Scientific Reports. 7: 12412. PMID 28963550 DOI: 10.1038/s41598-017-12603-0  0.626
2017 McQueen J, Ryan TJ, McKay S, Marwick KF, Baxter PE, Carpanini SM, Wishart TM, Gillingwater TH, Manson JC, Wyllie DJ, Grant SG, McColl B, Komiyama N, Hardingham GE. Pro-death NMDA receptor signaling is promoted by the GluN2B C-terminus independently of DAPK1. Elife. 6. PMID 28731405 DOI: 10.7554/Elife.17161  0.49
2017 Boyd PJ, Tu WY, Shorrock HK, Groen EJN, Carter RN, Powis RA, Thomson SR, Thomson D, Graham LC, Motyl AAL, Wishart TM, Highley JR, Morton NM, Becker T, Becker CG, et al. Bioenergetic status modulates motor neuron vulnerability and pathogenesis in a zebrafish model of spinal muscular atrophy. Plos Genetics. 13: e1006744. PMID 28426667 DOI: 10.1371/journal.pgen.1006744  0.61
2017 Carpanini SM, Wishart TM, Gillingwater TH, Manson JC, Summers KM. Analysis of gene expression in the nervous system identifies key genes and novel candidates for health and disease. Neurogenetics. PMID 28190221 DOI: 10.1007/s10048-017-0509-5  0.534
2017 Amorim IS, Graham LC, Carter RN, Morton NM, Hammachi F, Kunath T, Pennetta G, Carpanini SM, Manson JC, Lamont DJ, Wishart TM, Gillingwater TH. Sideroflexin 3 is a α-synuclein-dependent mitochondrial protein that regulates synaptic morphology. Journal of Cell Science. PMID 28049716 DOI: 10.1242/Jcs.194241  0.564
2017 McQueen J, Ryan TJ, McKay S, Marwick K, Baxter P, Carpanini SM, Wishart TM, Gillingwater TH, Manson JC, Wyllie DJA, Grant SGN, McColl BW, Komiyama NH, Hardingham GE. Author response: Pro-death NMDA receptor signaling is promoted by the GluN2B C-terminus independently of Dapk1 Elife. DOI: 10.7554/Elife.17161.024  0.445
2016 Powis RA, Karyka E, Boyd P, Côme J, Jones RA, Zheng Y, Szunyogova E, Groen EJ, Hunter G, Thomson D, Wishart TM, Becker CG, Parson SH, Martinat C, Azzouz M, et al. Systemic restoration of UBA1 ameliorates disease in spinal muscular atrophy. Jci Insight. 1: e87908. PMID 27699224 DOI: 10.1172/jci.insight.87908  0.753
2016 Fuller HR, Gillingwater TH, Wishart TM. Commonality amid diversity: Multi-study proteomic identification of conserved disease mechanisms in spinal muscular atrophy. Neuromuscular Disorders : Nmd. PMID 27460344 DOI: 10.1016/j.nmd.2016.06.004  0.591
2016 Mcgorum B, Scholes S, Milne E, Eaton S, Wishart T, Poxton I, Moss S, Wernery U, Davey T, Harris J, Pirie R. Equine grass sickness, but not botulism, causes autonomic and enteric neurodegeneration and increases SNARE protein expression within neuronal perikarya Journal of Equine Veterinary Science. 39: S40-S41. DOI: 10.1016/J.JEVS.2016.02.089  0.516
2015 Amorim IS, Mitchell NL, Palmer DN, Sawiak SJ, Mason R, Wishart TM, Gillingwater TH. Molecular neuropathology of the synapse in sheep with CLN5 Batten disease. Brain and Behavior. 5: e00401. PMID 26664787 DOI: 10.1002/Brb3.401  0.612
2015 McGorum BC, Pirie RS, Eaton SL, Keen JA, Cumyn EM, Arnott DM, Chen W, Lamont DJ, Graham LC, Llavero Hurtado M, Pemberton A, Wishart TM. Proteomic Profiling of Cranial (Superior) Cervical Ganglia Reveals Beta-Amyloid & Ubiquitin Proteasome System Perturbations in an Equine Multiple System Neuropathy. Molecular & Cellular Proteomics : McP. PMID 26364976 DOI: 10.1074/mcp.M115.054635  0.313
2014 Eaton SL, Hurtado ML, Oldknow KJ, Graham LC, Marchant TW, Gillingwater TH, Farquharson C, Wishart TM. A guide to modern quantitative fluorescent western blotting with troubleshooting strategies. Journal of Visualized Experiments : Jove. e52099. PMID 25490604 DOI: 10.3791/52099  0.489
2014 Roche SL, Sherman DL, Dissanayake K, Soucy G, Desmazieres A, Lamont DJ, Peles E, Julien JP, Wishart TM, Ribchester RR, Brophy PJ, Gillingwater TH. Loss of glial neurofascin155 delays developmental synapse elimination at the neuromuscular junction. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 12904-18. PMID 25232125 DOI: 10.1523/Jneurosci.1725-14.2014  0.798
2014 Aghamaleky Sarvestany A, Hunter G, Tavendale A, Lamont DJ, Llavero Hurtado M, Graham LC, Wishart TM, Gillingwater TH. Label-free quantitative proteomic profiling identifies disruption of ubiquitin homeostasis as a key driver of Schwann cell defects in spinal muscular atrophy. Journal of Proteome Research. 13: 4546-57. PMID 25151848 DOI: 10.1021/pr500492j  0.617
2014 Powis RA, Mutsaers CA, Wishart TM, Hunter G, Wirth B, Gillingwater TH. Increased levels of UCHL1 are a compensatory response to disrupted ubiquitin homeostasis in spinal muscular atrophy and do not represent a viable therapeutic target. Neuropathology and Applied Neurobiology. 40: 873-87. PMID 25041530 DOI: 10.1111/nan.12168  0.543
2014 Carpanini SM, McKie L, Thomson D, Wright AK, Gordon SL, Roche SL, Handley MT, Morrison H, Brownstein D, Wishart TM, Cousin MA, Gillingwater TH, Aligianis IA, Jackson IJ. A novel mouse model of Warburg Micro syndrome reveals roles for RAB18 in eye development and organisation of the neuronal cytoskeleton. Disease Models & Mechanisms. 7: 711-22. PMID 24764192 DOI: 10.1242/Dmm.015222  0.621
2014 Wishart TM, Mutsaers CA, Riessland M, Reimer MM, Hunter G, Hannam ML, Eaton SL, Fuller HR, Roche SL, Somers E, Morse R, Young PJ, Lamont DJ, Hammerschmidt M, Joshi A, et al. Dysregulation of ubiquitin homeostasis and β-catenin signaling promote spinal muscular atrophy. The Journal of Clinical Investigation. 124: 1821-34. PMID 24590288 DOI: 10.1172/Jci71318  0.733
2013 Mutsaers CA, Lamont DJ, Hunter G, Wishart TM, Gillingwater TH. Label-free proteomics identifies Calreticulin and GRP75/Mortalin as peripherally accessible protein biomarkers for spinal muscular atrophy. Genome Medicine. 5: 95. PMID 24134804 DOI: 10.1186/gm498  0.553
2013 Eaton SL, Roche SL, Llavero Hurtado M, Oldknow KJ, Farquharson C, Gillingwater TH, Wishart TM. Total protein analysis as a reliable loading control for quantitative fluorescent Western blotting. Plos One. 8: e72457. PMID 24023619 DOI: 10.1371/journal.pone.0072457  0.523
2012 Wishart TM, Rooney TM, Lamont DJ, Wright AK, Morton AJ, Jackson M, Freeman MR, Gillingwater TH. Combining comparative proteomics and molecular genetics uncovers regulators of synaptic and axonal stability and degeneration in vivo. Plos Genetics. 8: e1002936. PMID 22952455 DOI: 10.1371/Journal.Pgen.1002936  0.646
2012 Avery MA, Rooney TM, Pandya JD, Wishart TM, Gillingwater TH, Geddes JW, Sullivan PG, Freeman MR. WldS prevents axon degeneration through increased mitochondrial flux and enhanced mitochondrial Ca2+ buffering. Current Biology : Cb. 22: 596-600. PMID 22425157 DOI: 10.1016/J.Cub.2012.02.043  0.556
2012 Thomson SR, Wishart TM, Patani R, Chandran S, Gillingwater TH. Using induced pluripotent stem cells (iPSC) to model human neuromuscular connectivity: promise or reality? Journal of Anatomy. 220: 122-30. PMID 22133357 DOI: 10.1111/j.1469-7580.2011.01459.x  0.577
2011 Mutsaers CA, Wishart TM, Lamont DJ, Riessland M, Schreml J, Comley LH, Murray LM, Parson SH, Lochmüller H, Wirth B, Talbot K, Gillingwater TH. Reversible molecular pathology of skeletal muscle in spinal muscular atrophy. Human Molecular Genetics. 20: 4334-44. PMID 21840928 DOI: 10.1093/Hmg/Ddr360  0.742
2011 Comley LH, Fuller HR, Wishart TM, Mutsaers CA, Thomson D, Wright AK, Ribchester RR, Morris GE, Parson SH, Horsburgh K, Gillingwater TH. ApoE isoform-specific regulation of regeneration in the peripheral nervous system. Human Molecular Genetics. 20: 2406-21. PMID 21478199 DOI: 10.1093/Hmg/Ddr147  0.783
2011 Comley LH, Wishart TM, Baxter B, Murray LM, Nimmo A, Thomson D, Parson SH, Gillingwater TH. Induction of cell stress in neurons from transgenic mice expressing yellow fluorescent protein: implications for neurodegeneration research. Plos One. 6: e17639. PMID 21408118 DOI: 10.1371/journal.pone.0017639  0.724
2010 Wright AK, Wishart TM, Ingham CA, Gillingwater TH. Synaptic protection in the brain of WldS mice occurs independently of age but is sensitive to gene-dose. Plos One. 5: e15108. PMID 21124744 DOI: 10.1371/journal.pone.0015108  0.6
2010 Wishart TM, Huang JP, Murray LM, Lamont DJ, Mutsaers CA, Ross J, Geldsetzer P, Ansorge O, Talbot K, Parson SH, Gillingwater TH. SMN deficiency disrupts brain development in a mouse model of severe spinal muscular atrophy. Human Molecular Genetics. 19: 4216-28. PMID 20705736 DOI: 10.1093/Hmg/Ddq340  0.75
2009 Wishart TM, Brownstein DG, Thomson D, Tabakova AM, Boothe KM, Tsao JW, Gillingwater TH. Expression of the neuroprotective slow Wallerian degeneration (WldS) gene in non-neuronal tissues. Bmc Neuroscience. 10: 148. PMID 20015399 DOI: 10.1186/1471-2202-10-148  0.622
2009 Kielar C, Wishart TM, Palmer A, Dihanich S, Wong AM, Macauley SL, Chan CH, Sands MS, Pearce DA, Cooper JD, Gillingwater TH. Molecular correlates of axonal and synaptic pathology in mouse models of Batten disease. Human Molecular Genetics. 18: 4066-80. PMID 19640925 DOI: 10.1093/hmg/ddp355  0.646
2009 Benedict JW, Getty AL, Wishart TM, Gillingwater TH, Pearce DA. Protein product of CLN6 gene responsible for variant late-onset infantile neuronal ceroid lipofuscinosis interacts with CRMP-2. Journal of Neuroscience Research. 87: 2157-66. PMID 19235893 DOI: 10.1002/Jnr.22032  0.528
2008 Murray LM, Thomson D, Conklin A, Wishart TM, Gillingwater TH. Loss of translation elongation factor (eEF1A2) expression in vivo differentiates between Wallerian degeneration and dying-back neuronal pathology. Journal of Anatomy. 213: 633-45. PMID 19094180 DOI: 10.1111/j.1469-7580.2008.01007.x  0.662
2008 Wishart TM, Pemberton HN, James SR, McCabe CJ, Gillingwater TH. Modified cell cycle status in a mouse model of altered neuronal vulnerability (slow Wallerian degeneration; Wlds) Genome Biology. 9. PMID 18570652 DOI: 10.1186/gb-2008-9-6-r101  0.618
2008 Wilbrey AL, Haley JE, Wishart TM, Conforti L, Morreale G, Beirowski B, Babetto E, Adalbert R, Gillingwater TH, Smith T, Wyllie DJ, Ribchester RR, Coleman MP. VCP binding influences intracellular distribution of the slow Wallerian degeneration protein, Wld(S). Molecular and Cellular Neurosciences. 38: 325-40. PMID 18468455 DOI: 10.1016/J.Mcn.2008.03.004  0.744
2007 Wishart TM, Macdonald SH, Chen PE, Shipston MJ, Coleman MP, Gillingwater TH, Ribchester RR. Design of a novel quantitative PCR (QPCR)-based protocol for genotyping mice carrying the neuroprotective Wallerian degeneration slow (Wlds) gene. Molecular Neurodegeneration. 2: 21. PMID 17971231 DOI: 10.1186/1750-1326-2-21  0.731
2007 Wishart TM, Paterson JM, Short DM, Meredith S, Robertson KA, Sutherland C, Cousin MA, Dutia MB, Gillingwater TH. Differential proteomics analysis of synaptic proteins identifies potential cellular targets and protein mediators of synaptic neuroprotection conferred by the slow Wallerian degeneration (Wlds) gene. Molecular & Cellular Proteomics : McP. 6: 1318-30. PMID 17470424 DOI: 10.1074/Mcp.M600457-Mcp200  0.647
2006 Wishart TM, Parson SH, Gillingwater TH. Synaptic vulnerability in neurodegenerative disease. Journal of Neuropathology and Experimental Neurology. 65: 733-9. PMID 16896307 DOI: 10.1097/01.jnen.0000228202.35163.c4  0.745
2006 Gillingwater TH, Ingham CA, Parry KE, Wright AK, Haley JE, Wishart TM, Arbuthnott GW, Ribchester RR. Delayed synaptic degeneration in the CNS of Wlds mice after cortical lesion. Brain : a Journal of Neurology. 129: 1546-56. PMID 16738060 DOI: 10.1093/brain/awl101  0.77
2006 Gillingwater TH, Wishart TM, Chen PE, Haley JE, Robertson K, MacDonald SH, Middleton S, Wawrowski K, Shipston MJ, Melmed S, Wyllie DJ, Skehel PA, Coleman MP, Ribchester RR. The neuroprotective WldS gene regulates expression of PTTG1 and erythroid differentiation regulator 1-like gene in mice and human cells. Human Molecular Genetics. 15: 625-35. PMID 16403805 DOI: 10.1093/Hmg/Ddi478  0.753
2006 Laser H, Conforti L, Morreale G, Mack TG, Heyer M, Haley JE, Wishart TM, Beirowski B, Walker SA, Haase G, Celik A, Adalbert R, Wagner D, Grumme D, Ribchester RR, et al. The slow Wallerian degeneration protein, WldS, binds directly to VCP/p97 and partially redistributes it within the nucleus. Molecular Biology of the Cell. 17: 1075-84. PMID 16371511 DOI: 10.1091/mbc.E05-04-0375  0.671
2004 Ribchester RR, Thomson D, Wood NI, Hinks T, Gillingwater TH, Wishart TM, Court FA, Morton AJ. Progressive abnormalities in skeletal muscle and neuromuscular junctions of transgenic mice expressing the Huntington's disease mutation European Journal of Neuroscience. 20: 3092-3114. PMID 15579164 DOI: 10.1111/J.1460-9568.2004.03783.X  0.783
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