Mark F. Bear - Publications

Affiliations: 
Brown University, Providence, RI 
 Massachusetts Institute of Technology, Cambridge, MA, United States 
Area:
visual system, development
Website:
http://bearlab-s1.mit.edu/BearLab/bear.html

197 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 De Jesús-Cortés H, Cramer TLM, Bowen DA, Reilly-Andújar F, Lu S, Gaier ED, Bear MF. Using the visual cliff and pole descent assays to detect binocular disruption in mice. Biorxiv : the Preprint Server For Biology. PMID 39386530 DOI: 10.1101/2023.05.29.542767  0.791
2023 Hayden DJ, Finnie PSB, Thomazeau A, Li AY, Cooke SF, Bear MF. Electrophysiological signatures of visual recognition memory across all layers of mouse V1. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 37714707 DOI: 10.1523/JNEUROSCI.0090-23.2023  0.822
2023 Hayden DJ, Finnie PSB, Thomazeau A, Li AY, Cooke SF, Bear MF. Electrophysiological signatures of visual recognition memory across all layers of mouse V1. Biorxiv : the Preprint Server For Biology. PMID 36747661 DOI: 10.1101/2023.01.25.524429  0.814
2022 Leet MP, Bear MF, Gaier ED. Metaplasticity: a key to visual recovery from amblyopia in adulthood? Current Opinion in Ophthalmology. PMID 36094025 DOI: 10.1097/ICU.0000000000000901  0.301
2022 Montgomery DP, Hayden DJ, Chaloner FA, Cooke SF, Bear MF. Stimulus-Selective Response Plasticity in Primary Visual Cortex: Progress and Puzzles. Frontiers in Neural Circuits. 15: 815554. PMID 35173586 DOI: 10.3389/fncir.2021.815554  0.84
2021 Stoppel DC, McCamphill PK, Senter RK, Heynen AJ, Bear MF. mGluR5 Negative Modulators for Fragile X: Treatment Resistance and Persistence. Frontiers in Psychiatry. 12: 718953. PMID 34658956 DOI: 10.3389/fpsyt.2021.718953  0.79
2021 Fong MF, Duffy KR, Leet MP, Candler CT, Bear MF. Correction of amblyopia in cats and mice after the critical period. Elife. 10. PMID 34464258 DOI: 10.7554/eLife.70023  0.62
2021 Finnie PSB, Komorowski RW, Bear MF. The spatiotemporal organization of experience dictates hippocampal involvement in primary visual cortical plasticity. Current Biology : Cb. PMID 34314678 DOI: 10.1016/j.cub.2021.06.079  0.793
2021 Venturino A, Schulz R, De Jesús-Cortés H, Maes ME, Nagy B, Reilly-Andújar F, Colombo G, Cubero RJA, Schoot Uiterkamp FE, Bear MF, Siegert S. Microglia enable mature perineuronal nets disassembly upon anesthetic ketamine exposure or 60-Hz light entrainment in the healthy brain. Cell Reports. 36: 109313. PMID 34233180 DOI: 10.1016/j.celrep.2021.109313  0.795
2021 Hayden DJ, Montgomery DP, Cooke SF, Bear MF. Visual recognition is heralded by shifts in local field potential oscillations and inhibitory networks in primary visual cortex. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 34103358 DOI: 10.1523/JNEUROSCI.0391-21.2021  0.823
2021 Kyrke-Smith M, Volk LJ, Cooke SF, Bear MF, Huganir RL, Shepherd JD. The immediate early gene is not required for hippocampal long-term potentiation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 33833081 DOI: 10.1523/JNEUROSCI.0008-20.2021  0.775
2020 Thomazeau A, Bosch M, Essayan-Perez S, Barnes SA, De Jesus-Cortes H, Bear MF. Dissociation of functional and structural plasticity of dendritic spines during NMDAR and mGluR-dependent long-term synaptic depression in wild-type and fragile X model mice. Molecular Psychiatry. PMID 32606374 DOI: 10.1038/S41380-020-0821-6  0.831
2020 Shemesh OA, Linghu C, Piatkevich KD, Goodwin D, Celiker OT, Gritton HJ, Romano MF, Gao R, Yu CJ, Tseng HA, Bensussen S, Narayan S, Yang CT, Freifeld L, Siciliano CA, ... ... Bear MF, et al. Precision Calcium Imaging of Dense Neural Populations via a Cell-Body-Targeted Calcium Indicator. Neuron. PMID 32592656 DOI: 10.1016/J.Neuron.2020.05.029  0.719
2020 McCamphill PK, Stoppel LJ, Senter RK, Lewis MC, Heynen AJ, Stoppel DC, Sridhar V, Collins KA, Shi X, Pan JQ, Madison J, Cottrell JR, Huber KM, Scolnick EM, Holson EB, ... ... Bear MF, et al. Selective inhibition of glycogen synthase kinase 3α corrects pathophysiology in a mouse model of fragile X syndrome. Science Translational Medicine. 12. PMID 32434848 DOI: 10.1126/Scitranslmed.Aam8572  0.792
2020 Lee Y, Han NE, Kim W, Kim JG, Lee IB, Choi SJ, Chun H, Seo M, Lee CJ, Koh HY, Kim JH, Baik JH, Bear MF, Choi SY, Yoon BJ. Dynamic Changes in the Bridging Collaterals of the Basal Ganglia Circuitry Control Stress-Related Behaviors in Mice. Molecules and Cells. PMID 31940718 DOI: 10.14348/Molcells.2019.0279  0.631
2019 Kim T, Chaloner FA, Cooke SF, Harnett MT, Bear MF. Opposing Somatic and Dendritic Expression of Stimulus-Selective Response Plasticity in Mouse Primary Visual Cortex. Frontiers in Cellular Neuroscience. 13: 555. PMID 32009901 DOI: 10.3389/Fncel.2019.00555  0.767
2019 Fong MF, Finnie PS, Kim T, Thomazeau A, Kaplan ES, Cooke SF, Bear MF. Distinct Laminar Requirements for NMDA Receptors in Experience-Dependent Visual Cortical Plasticity. Cerebral Cortex (New York, N.Y. : 1991). PMID 31832634 DOI: 10.1093/Cercor/Bhz260  0.837
2019 Asiminas A, Jackson AD, Louros SR, Till SM, Spano T, Dando O, Bear MF, Chattarji S, Hardingham GE, Osterweil EK, Wyllie DJA, Wood ER, Kind PC. Sustained correction of associative learning deficits after brief, early treatment in a rat model of Fragile X Syndrome. Science Translational Medicine. 11. PMID 31142675 DOI: 10.1126/Scitranslmed.Aao0498  0.322
2019 Gaier ED, Montgomery D, Heynen A, Bear MF. Exploiting principles of timing-dependent plasticity to treat amblyopia Journal of American Association For Pediatric Ophthalmology and Strabismus. 23: e29. DOI: 10.1016/j.jaapos.2019.08.100  0.332
2018 Bear MF, Cooke SF, Giese KP, Kaang BK, Kennedy MB, Kim JI, Morris RGM, Park P. In memoriam: John Lisman - commentaries on CaMKII as a memory molecule. Molecular Brain. 11: 76. PMID 30593282 DOI: 10.1186/s13041-018-0419-y  0.668
2018 Eavri R, Shepherd J, Welsh CA, Flanders GH, Bear M, Nedivi E. Interneuron simplification and loss of structural plasticity as markers of aging-related functional decline. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 30108129 DOI: 10.1523/JNEUROSCI.0808-18.2018  0.636
2017 Duffy KR, Fong MF, Mitchell DE, Bear MF. Recovery from the anatomical effects of long-term monocular deprivation in cat lateral geniculate nucleus. The Journal of Comparative Neurology. PMID 29023717 DOI: 10.1002/Cne.24336  0.662
2017 Schecter RW, Maher EE, Welsh CA, Stevens B, Erisir A, Bear MF. Experience-dependent synaptic plasticity in V1 occurs without microglial CX3CR1. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 28951447 DOI: 10.1523/Jneurosci.2679-16.2017  0.575
2017 Jenks KR, Kim T, Pastuzyn ED, Okuno H, Taibi AV, Bito H, Bear MF, Shepherd JD. Arc restores juvenile plasticity in adult mouse visual cortex. Proceedings of the National Academy of Sciences of the United States of America. PMID 28790183 DOI: 10.1073/Pnas.1700866114  0.711
2017 Stoppel LJ, Auerbach BD, Senter RK, Preza AR, Lefkowitz RJ, Bear MF. β-Arrestin2 Couples Metabotropic Glutamate Receptor 5 to Neuronal Protein Synthesis and Is a Potential Target to Treat Fragile X. Cell Reports. 18: 2807-2814. PMID 28329674 DOI: 10.1016/J.Celrep.2017.02.075  0.808
2016 Tao J, Wu H, Coronado AA, de Laittre E, Osterweil EK, Zhang Y, Bear MF. Negative Allosteric Modulation of mGluR5 Partially Corrects Pathophysiology in a Mouse Model of Rett Syndrome. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 11946-11958. PMID 27881780 DOI: 10.1523/Jneurosci.0672-16.2016  0.753
2016 Fong MF, Mitchell DE, Duffy KR, Bear MF. Rapid recovery from the effects of early monocular deprivation is enabled by temporary inactivation of the retinas. Proceedings of the National Academy of Sciences of the United States of America. PMID 27856748 DOI: 10.1073/Pnas.1613279113  0.728
2016 Kaplan ES, Cooke SF, Komorowski RW, Chubykin AA, Thomazeau A, Khibnik LA, Gavornik JP, Bear MF. Contrasting roles for parvalbumin-expressing inhibitory neurons in two forms of adult visual cortical plasticity. Elife. 5. PMID 26943618 DOI: 10.7554/Elife.11450  0.819
2016 Kaplan ES, Cooke SF, Komorowski RW, Chubykin AA, Thomazeau A, Khibnik LA, Gavornik JP, Bear MF. Author response: Contrasting roles for parvalbumin-expressing inhibitory neurons in two forms of adult visual cortical plasticity Elife. DOI: 10.7554/Elife.11450.026  0.812
2015 Prilutsky D, Kho AT, Palmer NP, Bhakar AL, Smedemark-Margulies N, Kong SW, Margulies DM, Bear MF, Kohane IS. Gene expression analysis in Fmr1KO mice identifies an immunological signature in brain tissue and mGluR5-related signaling in primary neuronal cultures. Molecular Autism. 6: 66. PMID 26697163 DOI: 10.1186/s13229-015-0061-9  0.781
2015 Barnes SA, Wijetunge LS, Jackson AD, Katsanevaki D, Osterweil EK, Komiyama NH, Grant SG, Bear MF, Nägerl UV, Kind PC, Wyllie DJ. Convergence of Hippocampal Pathophysiology in Syngap+/- and Fmr1-/y Mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 15073-81. PMID 26558778 DOI: 10.1523/Jneurosci.1087-15.2015  0.398
2015 Sidorov MS, Kaplan ES, Osterweil EK, Lindemann L, Bear MF. Metabotropic glutamate receptor signaling is required for NMDA receptor-dependent ocular dominance plasticity and LTD in visual cortex. Proceedings of the National Academy of Sciences of the United States of America. PMID 26417096 DOI: 10.1073/Pnas.1512878112  0.848
2015 Till SM, Asiminas A, Jackson AD, Katsanevaki D, Barnes SA, Osterweil EK, Bear MF, Chattarji S, Wood ER, Wyllie DJ, Kind PC. Conserved hippocampal cellular pathophysiology but distinct behavioural deficits in a new rat model of FXS. Human Molecular Genetics. PMID 26243794 DOI: 10.1093/Hmg/Ddv299  0.373
2015 Cooke SF, Bear MF. Visual recognition memory: a view from V1. Current Opinion in Neurobiology. 35: 57-65. PMID 26151761 DOI: 10.1016/j.conb.2015.06.008  0.743
2015 Cooke SF, Komorowski RW, Kaplan ES, Gavornik JP, Bear MF. Erratum: Visual recognition memory, manifested as long-term habituation, requires synaptic plasticity in V1. Nature Neuroscience. 18: 926. PMID 26007217 DOI: 10.1038/nn0615-926d  0.817
2015 Cooke SF, Komorowski RW, Kaplan ES, Gavornik JP, Bear MF. Visual recognition memory, manifested as long-term habituation, requires synaptic plasticity in V1. Nature Neuroscience. 18: 262-71. PMID 25599221 DOI: 10.1038/Nn.3920  0.821
2015 Tian D, Stoppel LJ, Heynen AJ, Lindemann L, Jaeschke G, Mills AA, Bear MF. Contribution of mGluR5 to pathophysiology in a mouse model of human chromosome 16p11.2 microdeletion. Nature Neuroscience. 18: 182-4. PMID 25581360 DOI: 10.1038/nn.3911  0.413
2015 Harrison RR, Kolb I, Kodandaramaiah SB, Chubykin AA, Yang A, Bear MF, Boyden ES, Forest CR. Microchip amplifier for in vitro, in vivo, and automated whole cell patch-clamp recording. Journal of Neurophysiology. 113: 1275-82. PMID 25429119 DOI: 10.1152/Jn.00629.2014  0.542
2015 Cooke SF, Bear MF. Visual recognition memory: A view from V1 Current Opinion in Neurobiology. 35: 57-65. DOI: 10.1016/j.conb.2015.06.008  0.683
2015 Bear MF, Connors BW, Paradiso MA. Neuroscience: Exploring the brain: Fourth edition Neuroscience: Exploring the Brain: Fourth Edition. 1-975.  0.721
2014 Gavornik JP, Bear MF. Higher brain functions served by the lowly rodent primary visual cortex. Learning & Memory (Cold Spring Harbor, N.Y.). 21: 527-33. PMID 25225298 DOI: 10.1101/lm.034355.114  0.813
2014 Sidorov MS, Krueger DD, Taylor M, Gisin E, Osterweil EK, Bear MF. Extinction of an instrumental response: a cognitive behavioral assay in Fmr1 knockout mice. Genes, Brain, and Behavior. PMID 24684608 DOI: 10.1111/Gbb.12137  0.801
2014 Gavornik JP, Bear MF. Learned spatiotemporal sequence recognition and prediction in primary visual cortex. Nature Neuroscience. 17: 732-7. PMID 24657967 DOI: 10.1038/nn.3683  0.782
2014 Cooke SF, Bear MF. How the mechanisms of long-term synaptic potentiation and depression serve experience-dependent plasticity in primary visual cortex. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 369: 20130284. PMID 24298166 DOI: 10.1098/rstb.2013.0284  0.801
2013 Lohith TG, Osterweil EK, Fujita M, Jenko KJ, Bear MF, Innis RB. Is metabotropic glutamate receptor 5 upregulated in prefrontal cortex in fragile X syndrome? Molecular Autism. 4: 15. PMID 23706040 DOI: 10.1186/2040-2392-4-15  0.384
2013 Sidorov MS, Auerbach BD, Bear MF. Fragile X mental retardation protein and synaptic plasticity. Molecular Brain. 6: 15. PMID 23566911 DOI: 10.1186/1756-6606-6-15  0.82
2013 Chubykin AA, Roach EB, Bear MF, Shuler MG. A cholinergic mechanism for reward timing within primary visual cortex. Neuron. 77: 723-35. PMID 23439124 DOI: 10.1016/J.Neuron.2012.12.039  0.823
2013 Osterweil EK, Chuang SC, Chubykin AA, Sidorov M, Bianchi R, Wong RK, Bear MF. Lovastatin corrects excess protein synthesis and prevents epileptogenesis in a mouse model of fragile X syndrome. Neuron. 77: 243-50. PMID 23352161 DOI: 10.1016/J.Neuron.2012.01.034  0.783
2012 Osterweil EK, Kind PC, Bear MF. Lifting the mood on treating fragile X. Biological Psychiatry. 72: 895-7. PMID 23121869 DOI: 10.1016/J.Biopsych.2012.09.017  0.367
2012 Cooper LN, Bear MF. The BCM theory of synapse modification at 30: interaction of theory with experiment. Nature Reviews. Neuroscience. 13: 798-810. PMID 23080416 DOI: 10.1038/nrn3353  0.631
2012 Henderson C, Wijetunge L, Kinoshita MN, Shumway M, Hammond RS, Postma FR, Brynczka C, Rush R, Thomas A, Paylor R, Warren ST, Vanderklish PW, Kind PC, Carpenter RL, Bear MF, et al. Reversal of disease-related pathologies in the fragile X mouse model by selective activation of GABAB receptors with arbaclofen. Science Translational Medicine. 4: 152ra128. PMID 22993295 DOI: 10.1126/Scitranslmed.3004218  0.422
2012 Michalon A, Sidorov M, Ballard TM, Ozmen L, Spooren W, Wettstein JG, Jaeschke G, Bear MF, Lindemann L. Chronic pharmacological mGlu5 inhibition corrects fragile X in adult mice. Neuron. 74: 49-56. PMID 22500629 DOI: 10.1016/J.Neuron.2012.03.009  0.8
2012 Bhakar AL, Dölen G, Bear MF. The pathophysiology of fragile X (and what it teaches us about synapses). Annual Review of Neuroscience. 35: 417-43. PMID 22483044 DOI: 10.1146/Annurev-Neuro-060909-153138  0.817
2012 Cooke SF, Bear MF. Stimulus-selective response plasticity in the visual cortex: an assay for the assessment of pathophysiology and treatment of cognitive impairment associated with psychiatric disorders. Biological Psychiatry. 71: 487-95. PMID 22019003 DOI: 10.1016/j.biopsych.2011.09.006  0.789
2011 Auerbach BD, Osterweil EK, Bear MF. Mutations causing syndromic autism define an axis of synaptic pathophysiology. Nature. 480: 63-8. PMID 22113615 DOI: 10.1038/Nature10658  0.411
2011 Rachmuth G, Shouval HZ, Bear MF, Poon CS. A biophysically-based neuromorphic model of spike rate- and timing-dependent plasticity. Proceedings of the National Academy of Sciences of the United States of America. 108: E1266-74. PMID 22089232 DOI: 10.1073/Pnas.1106161108  0.692
2011 Javitt DC, Schoepp D, Kalivas PW, Volkow ND, Zarate C, Merchant K, Bear MF, Umbricht D, Hajos M, Potter WZ, Lee CM. Translating glutamate: from pathophysiology to treatment. Science Translational Medicine. 3: 102mr2. PMID 21957170 DOI: 10.1126/Scitranslmed.3002804  0.304
2011 Shepherd JD, Bear MF. New views of Arc, a master regulator of synaptic plasticity. Nature Neuroscience. 14: 279-84. PMID 21278731 DOI: 10.1038/nn.2708  0.622
2011 Krueger DD, Osterweil EK, Chen SP, Tye LD, Bear MF. Cognitive dysfunction and prefrontal synaptic abnormalities in a mouse model of fragile X syndrome. Proceedings of the National Academy of Sciences of the United States of America. 108: 2587-92. PMID 21262808 DOI: 10.1073/Pnas.1013855108  0.805
2011 Krueger DD, Bear MF. Toward fulfilling the promise of molecular medicine in fragile X syndrome. Annual Review of Medicine. 62: 411-29. PMID 21090964 DOI: 10.1146/annurev-med-061109-134644  0.371
2011 Choi CH, Schoenfeld BP, Bell AJ, Hinchey P, Kollaros M, Gertner MJ, Woo NH, Tranfaglia MR, Bear MF, Zukin RS, McDonald TV, Jongens TA, McBride SM. Pharmacological reversal of synaptic plasticity deficits in the mouse model of fragile X syndrome by group II mGluR antagonist or lithium treatment. Brain Research. 1380: 106-19. PMID 21078304 DOI: 10.1016/J.Brainres.2010.11.032  0.385
2010 Cooke SF, Bear MF. Visual experience induces long-term potentiation in the primary visual cortex. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 16304-13. PMID 21123576 DOI: 10.1523/JNEUROSCI.4333-10.2010  0.79
2010 Osterweil EK, Krueger DD, Reinhold K, Bear MF. Hypersensitivity to mGluR5 and ERK1/2 leads to excessive protein synthesis in the hippocampus of a mouse model of fragile X syndrome. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 15616-27. PMID 21084617 DOI: 10.1523/Jneurosci.3888-10.2010  0.394
2010 Coleman JE, Nahmani M, Gavornik JP, Haslinger R, Heynen AJ, Erisir A, Bear MF. Rapid structural remodeling of thalamocortical synapses parallels experience-dependent functional plasticity in mouse primary visual cortex. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 9670-82. PMID 20660250 DOI: 10.1523/Jneurosci.1248-10.2010  0.853
2010 Smith GB, Bear MF. Bidirectional ocular dominance plasticity of inhibitory networks: recent advances and unresolved questions. Frontiers in Cellular Neuroscience. 4: 21. PMID 20592959 DOI: 10.3389/fncel.2010.00021  0.607
2010 Auerbach BD, Bear MF. Loss of the fragile X mental retardation protein decouples metabotropic glutamate receptor dependent priming of long-term potentiation from protein synthesis. Journal of Neurophysiology. 104: 1047-51. PMID 20554840 DOI: 10.1152/jn.00449.2010  0.455
2010 Khibnik LA, Cho KK, Bear MF. Relative contribution of feedforward excitatory connections to expression of ocular dominance plasticity in layer 4 of visual cortex. Neuron. 66: 493-500. PMID 20510854 DOI: 10.1016/j.neuron.2010.04.012  0.851
2010 Dölen G, Carpenter RL, Ocain TD, Bear MF. Mechanism-based approaches to treating fragile X. Pharmacology & Therapeutics. 127: 78-93. PMID 20303363 DOI: 10.1016/J.Pharmthera.2010.02.008  0.307
2010 McCurry CL, Shepherd JD, Tropea D, Wang KH, Bear MF, Sur M. Loss of Arc renders the visual cortex impervious to the effects of sensory experience or deprivation. Nature Neuroscience. 13: 450-7. PMID 20228806 DOI: 10.1038/Nn.2508  0.689
2010 Cho KK, Bear MF. Promoting neurological recovery of function via metaplasticity. Future Neurology. 5: 21-26. PMID 20209094 DOI: 10.2217/fnl.09.62  0.71
2010 Krueger DD, Osterweil EK, Bear MF. Activation of mGluR5 induces rapid and long-lasting protein kinase D phosphorylation in hippocampal neurons. Journal of Molecular Neuroscience : Mn. 42: 1-8. PMID 20177824 DOI: 10.1007/S12031-010-9338-9  0.409
2009 Dölen G, Bear MF. Fragile x syndrome and autism: from disease model to therapeutic targets. Journal of Neurodevelopmental Disorders. 1: 133-40. PMID 21547712 DOI: 10.1007/S11689-009-9015-X  0.772
2009 Yoon BJ, Smith GB, Heynen AJ, Neve RL, Bear MF. Essential role for a long-term depression mechanism in ocular dominance plasticity. Proceedings of the National Academy of Sciences of the United States of America. 106: 9860-5. PMID 19470483 DOI: 10.1073/pnas.0901305106  0.748
2009 Wiig KA, Whitlock JR, Epstein MH, Carpenter RL, Bear MF. The levo enantiomer of amphetamine increases memory consolidation and gene expression in the hippocampus without producing locomotor stimulation. Neurobiology of Learning and Memory. 92: 106-13. PMID 19368765 DOI: 10.1016/j.nlm.2009.02.001  0.74
2009 Gavornik JP, Shuler MG, Loewenstein Y, Bear MF, Shouval HZ. Learning reward timing in cortex through reward dependent expression of synaptic plasticity. Proceedings of the National Academy of Sciences of the United States of America. 106: 6826-31. PMID 19346478 DOI: 10.1073/Pnas.0901835106  0.819
2009 Coleman JE, Law K, Bear MF. Anatomical origins of ocular dominance in mouse primary visual cortex. Neuroscience. 161: 561-71. PMID 19327388 DOI: 10.1016/j.neuroscience.2009.03.045  0.619
2009 Cho KK, Khibnik L, Philpot BD, Bear MF. The ratio of NR2A/B NMDA receptor subunits determines the qualities of ocular dominance plasticity in visual cortex. Proceedings of the National Academy of Sciences of the United States of America. 106: 5377-82. PMID 19276107 DOI: 10.1073/pnas.0808104106  0.843
2009 Linden ML, Heynen AJ, Haslinger RH, Bear MF. Thalamic activity that drives visual cortical plasticity. Nature Neuroscience. 12: 390-2. PMID 19252494 DOI: 10.1038/Nn.2284  0.824
2009 Smith GB, Heynen AJ, Bear MF. Bidirectional synaptic mechanisms of ocular dominance plasticity in visual cortex. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 364: 357-67. PMID 18977732 DOI: 10.1098/rstb.2008.0198  0.615
2008 Kelleher RJ, Bear MF. The autistic neuron: troubled translation? Cell. 135: 401-6. PMID 18984149 DOI: 10.1016/j.cell.2008.10.017  0.354
2008 Lee S, Kim W, Ham BJ, Chen W, Bear MF, Yoon BJ. Activity-dependent NR2B expression is mediated by MeCP2-dependent epigenetic regulation. Biochemical and Biophysical Research Communications. 377: 930-4. PMID 18952054 DOI: 10.1016/J.Bbrc.2008.10.082  0.664
2008 Blais BS, Frenkel MY, Kuindersma SR, Muhammad R, Shouval HZ, Cooper LN, Bear MF. Recovery from monocular deprivation using binocular deprivation. Journal of Neurophysiology. 100: 2217-24. PMID 18650311 DOI: 10.1152/Jn.90411.2008  0.821
2008 Liu CH, Heynen AJ, Shuler MG, Bear MF. Cannabinoid receptor blockade reveals parallel plasticity mechanisms in different layers of mouse visual cortex. Neuron. 58: 340-5. PMID 18466745 DOI: 10.1016/j.neuron.2008.02.020  0.831
2008 Hung AY, Futai K, Sala C, Valtschanoff JG, Ryu J, Woodworth MA, Kidd FL, Sung CC, Miyakawa T, Bear MF, Weinberg RJ, Sheng M. Smaller dendritic spines, weaker synaptic transmission, but enhanced spatial learning in mice lacking Shank1. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 1697-708. PMID 18272690 DOI: 10.1523/Jneurosci.3032-07.2008  0.441
2008 Dölen G, Bear MF. Role for metabotropic glutamate receptor 5 (mGluR5) in the pathogenesis of fragile X syndrome. The Journal of Physiology. 586: 1503-8. PMID 18202092 DOI: 10.1016/J.Neures.2009.09.1647  0.342
2008 Bear MF, Dölen G, Osterweil E, Nagarajan N. Fragile X: translation in action. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 33: 84-7. PMID 17940551 DOI: 10.1038/Sj.Npp.1301610  0.621
2008 Bear M. [PL02]: Modification of visual cortex by experience International Journal of Developmental Neuroscience. 26: 827-827. DOI: 10.1016/j.ijdevneu.2008.09.009  0.433
2007 Dölen G, Osterweil E, Rao BS, Smith GB, Auerbach BD, Chattarji S, Bear MF. Correction of fragile X syndrome in mice. Neuron. 56: 955-62. PMID 18093519 DOI: 10.1016/J.Neuron.2007.12.001  0.499
2007 Catania MV, D'Antoni S, Bonaccorso CM, Aronica E, Bear MF, Nicoletti F. Group I metabotropic glutamate receptors: a role in neurodevelopmental disorders? Molecular Neurobiology. 35: 298-307. PMID 17917118 DOI: 10.1007/S12035-007-0022-1  0.412
2007 Philpot BD, Cho KK, Bear MF. Obligatory role of NR2A for metaplasticity in visual cortex. Neuron. 53: 495-502. PMID 17296552 DOI: 10.1016/j.neuron.2007.01.027  0.85
2007 Crozier RA, Wang Y, Liu CH, Bear MF. Deprivation-induced synaptic depression by distinct mechanisms in different layers of mouse visual cortex. Proceedings of the National Academy of Sciences of the United States of America. 104: 1383-8. PMID 17227847 DOI: 10.1073/Pnas.0609596104  0.851
2007 Morishita W, Lu W, Smith GB, Nicoll RA, Bear MF, Malenka RC. Activation of NR2B-containing NMDA receptors is not required for NMDA receptor-dependent long-term depression. Neuropharmacology. 52: 71-6. PMID 16899258 DOI: 10.1016/j.neuropharm.2006.07.005  0.819
2007 Chen WS, Bear MF. Activity-dependent regulation of NR2B translation contributes to metaplasticity in mouse visual cortex. Neuropharmacology. 52: 200-14. PMID 16895734 DOI: 10.1016/J.Neuropharm.2006.07.003  0.67
2006 Whitlock JR, Heynen AJ, Shuler MG, Bear MF. Learning induces long-term potentiation in the hippocampus. Science (New York, N.Y.). 313: 1093-7. PMID 16931756 DOI: 10.1126/science.1128134  0.787
2006 Frenkel MY, Sawtell NB, Diogo AC, Yoon B, Neve RL, Bear MF. Instructive effect of visual experience in mouse visual cortex. Neuron. 51: 339-49. PMID 16880128 DOI: 10.1016/J.Neuron.2006.06.026  0.827
2006 Iny K, Heynen AJ, Sklar E, Bear MF. Bidirectional modifications of visual acuity induced by monocular deprivation in juvenile and adult rats. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 7368-74. PMID 16837583 DOI: 10.1523/JNEUROSCI.0124-06.2006  0.385
2006 Shuler MG, Bear MF. Reward timing in the primary visual cortex. Science (New York, N.Y.). 311: 1606-9. PMID 16543459 DOI: 10.1126/science.1123513  0.441
2006 Rittenhouse CD, Siegler BA, Voelker CC, Voelker CA, Shouval HZ, Paradiso MA, Bear MF. Stimulus for rapid ocular dominance plasticity in visual cortex. Journal of Neurophysiology. 95: 2947-50. PMID 16481452 DOI: 10.1152/Jn.01328.2005  0.827
2006 Rittenhouse CD, Siegler BA, Voelker CC, Shouval HZ, Paradiso MA, Bear MF. Erratum: Orientation-selective adaptation to first- and second-order patterns in human visual cortex (Journal of Neurophysiology (February 2006) 95, (862-881) DOI: 10.1152/jn.00668.2005) Journal of Neurophysiology. 96. DOI: 10.1152/Jn.00517.2006  0.799
2005 Bear MF. Therapeutic implications of the mGluR theory of fragile X mental retardation. Genes, Brain, and Behavior. 4: 393-8. PMID 16098137 DOI: 10.1111/j.1601-183X.2005.00135.x  0.321
2005 Dölen G, Bear MF. Courting a cure for fragile X. Neuron. 45: 642-4. PMID 15748838 DOI: 10.1016/j.neuron.2005.02.021  0.311
2005 Snyder EM, Colledge M, Crozier RA, Chen WS, Scott JD, Bear MF. Role for A kinase-anchoring proteins (AKAPS) in glutamate receptor trafficking and long term synaptic depression. The Journal of Biological Chemistry. 280: 16962-8. PMID 15718245 DOI: 10.1074/Jbc.M409693200  0.834
2004 Frenkel MY, Bear MF. How monocular deprivation shifts ocular dominance in visual cortex of young mice. Neuron. 44: 917-23. PMID 15603735 DOI: 10.1016/j.neuron.2004.12.003  0.819
2004 Malenka RC, Bear MF. LTP and LTD: an embarrassment of riches. Neuron. 44: 5-21. PMID 15450156 DOI: 10.1016/j.neuron.2004.09.012  0.616
2004 Wallace W, Bear MF. A morphological correlate of synaptic scaling in visual cortex. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 6928-38. PMID 15295028 DOI: 10.1523/Jneurosci.1110-04.2004  0.678
2004 Bear MF, Huber KM, Warren ST. The mGluR theory of fragile X mental retardation. Trends in Neurosciences. 27: 370-7. PMID 15219735 DOI: 10.1016/J.Tins.2004.04.009  0.638
2004 Nahm WK, Philpot BD, Adams MM, Badiavas EV, Zhou LH, Butmarc J, Bear MF, Falanga V. Significance of N-methyl-D-aspartate (NMDA) receptor-mediated signaling in human keratinocytes. Journal of Cellular Physiology. 200: 309-17. PMID 15174101 DOI: 10.1002/jcp.20010  0.802
2004 Gallagher SM, Daly CA, Bear MF, Huber KM. Extracellular signal-regulated protein kinase activation is required for metabotropic glutamate receptor-dependent long-term depression in hippocampal area CA1. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 4859-64. PMID 15152046 DOI: 10.1523/JNEUROSCI.5407-03.2004  0.669
2003 Colledge M, Snyder EM, Crozier RA, Soderling JA, Jin Y, Langeberg LK, Lu H, Bear MF, Scott JD. Ubiquitination regulates PSD-95 degradation and AMPA receptor surface expression. Neuron. 40: 595-607. PMID 14642282 DOI: 10.1016/S0896-6273(03)00687-1  0.82
2003 Heynen AJ, Yoon BJ, Liu CH, Chung HJ, Huganir RL, Bear MF. Molecular mechanism for loss of visual cortical responsiveness following brief monocular deprivation. Nature Neuroscience. 6: 854-62. PMID 12886226 DOI: 10.1038/Nn1100  0.856
2003 Philpot BD, Espinosa JS, Bear MF. Evidence for altered NMDA receptor function as a basis for metaplasticity in visual cortex. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 5583-8. PMID 12843259 DOI: 10.1523/Jneurosci.23-13-05583.2003  0.825
2003 Sawtell NB, Frenkel MY, Philpot BD, Nakazawa K, Tonegawa S, Bear MF. NMDA receptor-dependent ocular dominance plasticity in adult visual cortex. Neuron. 38: 977-85. PMID 12818182 DOI: 10.1016/S0896-6273(03)00323-4  0.836
2003 Bear MF. Bidirectional synaptic plasticity: from theory to reality. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 358: 649-55. PMID 12740110 DOI: 10.1098/rstb.2002.1255  0.494
2003 Sawtell NB, Frenkel MY, Philpot BD, Nakazawa K, Tonegawa S, Bear MF. Erratum Neuron. 39: 727. DOI: 10.1016/S0896-6273(03)00475-6  0.738
2003 Jackson JD, Yezzi A, Wallace W, Bear MF. Segmentation of coarse and fine scale features using multi-scale diffusion and Mumford-Shah Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). 2695: 615-624. DOI: 10.1007/3-540-44935-3_43  0.54
2002 Shouval HZ, Bear MF, Cooper LN. A unified model of NMDA receptor-dependent bidirectional synaptic plasticity. Proceedings of the National Academy of Sciences of the United States of America. 99: 10831-6. PMID 12136127 DOI: 10.1073/Pnas.152343099  0.786
2002 Huber KM, Gallagher SM, Warren ST, Bear MF. Altered synaptic plasticity in a mouse model of fragile X mental retardation. Proceedings of the National Academy of Sciences of the United States of America. 99: 7746-50. PMID 12032354 DOI: 10.1073/Pnas.122205699  0.69
2002 Philpot BD, Bear MF. Synaptic plasticity in an altered state. Neuron. 33: 665-7. PMID 11879642 DOI: 10.1016/S0896-6273(02)00618-9  0.759
2001 Heynen AJ, Bear MF. Long-term potentiation of thalamocortical transmission in the adult visual cortex in vivo. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 9801-13. PMID 11739588 DOI: 10.1523/Jneurosci.21-24-09801.2001  0.536
2001 Wells DG, Dong X, Quinlan EM, Huang YS, Bear MF, Richter JD, Fallon JR. A role for the cytoplasmic polyadenylation element in NMDA receptor-regulated mRNA translation in neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 9541-8. PMID 11739565 DOI: 10.1523/Jneurosci.21-24-09541.2001  0.819
2001 Zeng H, Chattarji S, Barbarosie M, Rondi-Reig L, Philpot BD, Miyakawa T, Bear MF, Tonegawa S. Forebrain-specific calcineurin knockout selectively impairs bidirectional synaptic plasticity and working/episodic-like memory. Cell. 107: 617-29. PMID 11733061 DOI: 10.1016/S0092-8674(01)00585-2  0.743
2001 Snyder EM, Philpot BD, Huber KM, Dong X, Fallon JR, Bear MF. Internalization of ionotropic glutamate receptors in response to mGluR activation. Nature Neuroscience. 4: 1079-85. PMID 11687813 DOI: 10.1038/nn746  0.828
2001 Philpot BD, Weisberg MP, Ramos MS, Sawtell NB, Tang YP, Tsien JZ, Bear MF. Effect of transgenic overexpression of NR2B on NMDA receptor function and synaptic plasticity in visual cortex. Neuropharmacology. 41: 762-70. PMID 11640931 DOI: 10.1016/S0028-3908(01)00136-8  0.859
2001 Abraham WC, Mason-Parker SE, Bear MF, Webb S, Tate WP. Heterosynaptic metaplasticity in the hippocampus in vivo: a BCM-like modifiable threshold for LTP. Proceedings of the National Academy of Sciences of the United States of America. 98: 10924-9. PMID 11517323 DOI: 10.1073/Pnas.181342098  0.471
2001 Rozas C, Frank H, Heynen AJ, Morales B, Bear MF, Kirkwood A. Developmental inhibitory gate controls the relay of activity to the superficial layers of the visual cortex. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 6791-801. PMID 11517267 DOI: 10.1523/Jneurosci.21-17-06791.2001  0.649
2001 Huber KM, Roder JC, Bear MF. Chemical induction of mGluR5- and protein synthesis--dependent long-term depression in hippocampal area CA1. Journal of Neurophysiology. 86: 321-5. PMID 11431513 DOI: 10.1152/Jn.2001.86.1.321  0.702
2001 Hannan AJ, Blakemore C, Katsnelson A, Vitalis T, Huber KM, Bear M, Roder J, Kim D, Shin HS, Kind PC. PLC-beta1, activated via mGluRs, mediates activity-dependent differentiation in cerebral cortex. Nature Neuroscience. 4: 282-8. PMID 11224545 DOI: 10.1038/85132  0.638
2001 Philpot BD, Sekhar AK, Shouval HZ, Bear MF. Visual experience and deprivation bidirectionally modify the composition and function of NMDA receptors in visual cortex. Neuron. 29: 157-69. PMID 11182088 DOI: 10.1016/S0896-6273(01)00187-8  0.858
2000 Heynen AJ, Quinlan EM, Bae DC, Bear MF. Bidirectional, activity-dependent regulation of glutamate receptors in the adult hippocampus in vivo. Neuron. 28: 527-36. PMID 11144361 DOI: 10.1016/S0896-6273(00)00130-6  0.733
2000 Lee HK, Barbarosie M, Kameyama K, Bear MF, Huganir RL. Regulation of distinct AMPA receptor phosphorylation sites during bidirectional synaptic plasticity. Nature. 405: 955-9. PMID 10879537 DOI: 10.1038/35016089  0.602
2000 Huber KM, Kayser MS, Bear MF. Role for rapid dendritic protein synthesis in hippocampal mGluR-dependent long-term depression. Science (New York, N.Y.). 288: 1254-7. PMID 10818003 DOI: 10.1126/science.288.5469.1254  0.806
1999 Sawtell NB, Huber KM, Roder JC, Bear MF. Induction of NMDA receptor-dependent long-term depression in visual cortex does not require metabotropic glutamate receptors. Journal of Neurophysiology. 82: 3594-7. PMID 10601487 DOI: 10.1152/Jn.1999.82.6.3594  0.841
1999 Quinlan EM, Olstein DH, Bear MF. Bidirectional, experience-dependent regulation of N-methyl-D-aspartate receptor subunit composition in the rat visual cortex during postnatal development. Proceedings of the National Academy of Sciences of the United States of America. 96: 12876-80. PMID 10536016 DOI: 10.1073/pnas.96.22.12876  0.766
1999 Bear MF, Rittenhouse CD. Molecular basis for induction of ocular dominance plasticity. Journal of Neurobiology. 41: 83-91. PMID 10504195 DOI: 10.1002/(SICI)1097-4695(199910)41:1<83::AID-NEU11>3.0.CO;2-Z  0.778
1999 Huang ZJ, Kirkwood A, Pizzorusso T, Porciatti V, Morales B, Bear MF, Maffei L, Tonegawa S. BDNF regulates the maturation of inhibition and the critical period of plasticity in mouse visual cortex. Cell. 98: 739-55. PMID 10499792 DOI: 10.1016/S0092-8674(00)81509-3  0.687
1999 Bear MF. Homosynaptic long-term depression: a mechanism for memory? Proceedings of the National Academy of Sciences of the United States of America. 96: 9457-8. PMID 10449713 DOI: 10.1073/pnas.96.17.9457  0.432
1999 Quinlan EM, Philpot BD, Huganir RL, Bear MF. Rapid, experience-dependent expression of synaptic NMDA receptors in visual cortex in vivo. Nature Neuroscience. 2: 352-7. PMID 10204542 DOI: 10.1038/7263  0.849
1999 Taubenfeld SM, Wiig KA, Bear MF, Alberini CM. A molecular correlate of memory and amnesia in the hippocampus. Nature Neuroscience. 2: 309-10. PMID 10204535 DOI: 10.1038/7217  0.329
1999 Kirkwood A, Rozas C, Kirkwood J, Perez F, Bear MF. Modulation of long-term synaptic depression in visual cortex by acetylcholine and norepinephrine. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 1599-609. PMID 10024347 DOI: 10.1523/Jneurosci.19-05-01599.1999  0.679
1999 Rittenhouse CD, Shouval HZ, Paradiso MA, Bear MF. Monocular deprivation induces homosynaptic long-term depression in visual cortex. Nature. 397: 347-50. PMID 9950426 DOI: 10.1038/16922  0.835
1998 Kameyama K, Lee HK, Bear MF, Huganir RL. Involvement of a postsynaptic protein kinase A substrate in the expression of homosynaptic long-term depression. Neuron. 21: 1163-75. PMID 9856471 DOI: 10.1016/S0896-6273(00)80633-9  0.612
1998 Lee HK, Kameyama K, Huganir RL, Bear MF. NMDA induces long-term synaptic depression and dephosphorylation of the GluR1 subunit of AMPA receptors in hippocampus. Neuron. 21: 1151-62. PMID 9856470 DOI: 10.1016/S0896-6273(00)80632-7  0.61
1998 Huber KM, Sawtell NB, Bear MF. Brain-derived neurotrophic factor alters the synaptic modification threshold in visual cortex. Neuropharmacology. 37: 571-9. PMID 9704998 DOI: 10.1016/S0028-3908(98)00050-1  0.837
1998 Huber KM, Sawtell NB, Bear MF. Effects of the metabotropic glutamate receptor antagonist MCPG on phosphoinositide turnover and synaptic plasticity in visual cortex. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 1-9. PMID 9412480 DOI: 10.1523/Jneurosci.18-01-00001.1998  0.849
1998 Bear MF, Cooper LN. From molecules to mental states Daedalus. 127: 131-144.  0.438
1997 Kirkwood A, Silva A, Bear MF. Age-dependent decrease of synaptic plasticity in the neocortex of alphaCaMKII mutant mice. Proceedings of the National Academy of Sciences of the United States of America. 94: 3380-3. PMID 9096402 DOI: 10.1073/pnas.94.7.3380  0.655
1996 Wiig KA, Cooper LN, Bear MF. Temporally graded retrograde amnesia following separate and combined lesions of the perirhinal cortex and fornix in the rat. Learning & Memory (Cold Spring Harbor, N.Y.). 3: 313-25. PMID 10456101 DOI: 10.1101/Lm.3.4.313  0.564
1996 Bear MF. Progress in understanding NMDA-receptor-dependent synaptic plasticity in the visual cortex. Journal of Physiology, Paris. 90: 223-7. PMID 9116672 DOI: 10.1016/S0928-4257(97)81428-3  0.558
1996 Bear MF. NMDA-receptor-dependent synaptic plasticity in the visual cortex. Progress in Brain Research. 108: 205-18. PMID 8979803 DOI: 10.1016/S0079-6123(08)62541-8  0.569
1996 Bear MF. A synaptic basis for memory storage in the cerebral cortex. Proceedings of the National Academy of Sciences of the United States of America. 93: 13453-9. PMID 8942956 DOI: 10.1073/pnas.93.24.13453  0.489
1996 Aizenman CD, Kirkwood A, Bear MF. A current source density analysis of evoked responses in slices of adult rat visual cortex: implications for the regulation of long-term potentiation. Cerebral Cortex (New York, N.Y. : 1991). 6: 751-8. PMID 8922331 DOI: 10.1093/Cercor/6.6.751  0.764
1996 Bear MF, Abraham WC. Long-term depression in hippocampus. Annual Review of Neuroscience. 19: 437-62. PMID 8833450 DOI: 10.1146/annurev.ne.19.030196.002253  0.424
1996 Abraham WC, Bear MF. Metaplasticity: the plasticity of synaptic plasticity. Trends in Neurosciences. 19: 126-30. PMID 8658594 DOI: 10.1016/S0166-2236(96)80018-X  0.477
1996 Kirkwood A, Rioult MC, Bear MF. Experience-dependent modification of synaptic plasticity in visual cortex. Nature. 381: 526-8. PMID 8632826 DOI: 10.1038/381526a0  0.708
1996 Heynen AJ, Abraham WC, Bear MF. Bidirectional modification of CA1 synapses in the adult hippocampus in vivo. Nature. 381: 163-6. PMID 8610015 DOI: 10.1038/381163a0  0.426
1996 Bear MF, Huber KM, Sawtell N. Synaptic plasticity, metaplasticity, and metabotropic glutamate receptors in the cerebral cortex Neuropharmacology. 35: A3. DOI: 10.1016/0028-3908(96)84658-2  0.704
1995 Kirkwood A, Bear MF. Elementary forms of synaptic plasticity in the visual cortex. Biological Research. 28: 73-80. PMID 8728822  0.659
1995 Kirkwood A, Lee HK, Bear MF. Co-regulation of long-term potentiation and experience-dependent synaptic plasticity in visual cortex by age and experience. Nature. 375: 328-31. PMID 7753198 DOI: 10.1038/375328a0  0.697
1995 Bear MF. Mechanism for a sliding synaptic modification threshold. Neuron. 15: 1-4. PMID 7619513 DOI: 10.1016/0896-6273(95)90056-X  0.402
1995 Selig DK, Lee HK, Bear MF, Malenka RC. Reexamination of the effects of MCPG on hippocampal LTP, LTD, and depotentiation. Journal of Neurophysiology. 74: 1075-82. PMID 7500133 DOI: 10.1152/Jn.1995.74.3.1075  0.753
1994 Kirkwood A, Bear MF. Homosynaptic long-term depression in the visual cortex. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 14: 3404-12. PMID 8182481 DOI: 10.1523/Jneurosci.14-05-03404.1994  0.695
1994 Gold JI, Bear MF. A model of dendritic spine Ca2+ concentration exploring possible bases for a sliding synaptic modification threshold. Proceedings of the National Academy of Sciences of the United States of America. 91: 3941-5. PMID 8171016 DOI: 10.1073/Pnas.91.9.3941  0.324
1994 Kirkwood A, Bear MF. Hebbian synapses in visual cortex. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 14: 1634-45. PMID 8126560 DOI: 10.1523/Jneurosci.14-03-01634.1994  0.636
1994 Bear MF, Malenka RC. Synaptic plasticity: LTP and LTD. Current Opinion in Neurobiology. 4: 389-99. PMID 7919934 DOI: 10.1016/0959-4388(94)90101-5  0.63
1994 Law CC, Bear MF, Cooper LN. Role of the visual environment in the formation of receptive fields according to the BCM theory. Progress in Brain Research. 102: 287-301. PMID 7800819 DOI: 10.1016/S0079-6123(08)60547-6  0.659
1993 Bear MF, Kirkwood A. Neocortical long-term potentiation. Current Opinion in Neurobiology. 3: 197-202. PMID 8513232 DOI: 10.1016/0959-4388(93)90210-P  0.648
1993 Kirkwood A, Dudek SM, Gold JT, Aizenman CD, Bear MF. Common forms of synaptic plasticity in the hippocampus and neocortex in vitro. Science (New York, N.Y.). 260: 1518-21. PMID 8502997 DOI: 10.1126/Science.8502997  0.831
1993 Dudek SM, Bear MF. Bidirectional long-term modification of synaptic effectiveness in the adult and immature hippocampus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 13: 2910-8. PMID 8331379 DOI: 10.1523/Jneurosci.13-07-02910.1993  0.629
1992 Bear MF, Press WA, Connors BW. Long-term potentiation in slices of kitten visual cortex and the effects of NMDA receptor blockade. Journal of Neurophysiology. 67: 841-51. PMID 1350308 DOI: 10.1152/Jn.1992.67.4.841  0.679
1992 Dudek SM, Bear MF. Homosynaptic long-term depression in area CA1 of hippocampus and effects of N-methyl-D-aspartate receptor blockade. Proceedings of the National Academy of Sciences of the United States of America. 89: 4363-7. PMID 1350090 DOI: 10.1073/Pnas.89.10.4363  0.661
1992 Bohner AP, Dudek SM, Bear MF. Effects of N-methyl-D-aspartate on quisqualate-stimulated phosphoinositide hydrolysis in slices of kitten striate cortex. Brain Research. 594: 146-9. PMID 1334763 DOI: 10.1016/0006-8993(92)91040-L  0.615
1991 Reynolds IJ, Bear MF. Effects of age and visual experience on [3H] MK801 binding to NMDA receptors in the kitten visual cortex. Experimental Brain Research. 85: 611-5. PMID 1833218 DOI: 10.1007/BF00231745  0.44
1991 Clothiaux EE, Bear MF, Cooper LN. Synaptic plasticity in visual cortex: comparison of theory with experiment. Journal of Neurophysiology. 66: 1785-804. PMID 1765807 DOI: 10.1152/Jn.1991.66.5.1785  0.773
1991 Alkon DL, Amaral DG, Bear MF, Black J, Carew TJ, Cohen NJ, Disterhoft JF, Eichenbaum H, Golski S, Gorman LK. Learning and memory. FESN Study Group. Brain Research. Brain Research Reviews. 16: 193-220. PMID 1760656 DOI: 10.1016/0165-0173(91)90005-S  0.409
1991 Bear MF, Dudek SM. Stimulation of phosphoinositide turnover by excitatory amino acids. Pharmacology, development, and role in visual cortical plasticity. Annals of the New York Academy of Sciences. 627: 42-56. PMID 1652918 DOI: 10.1111/j.1749-6632.1991.tb25912.x  0.698
1990 Juliano SL, Ma W, Bear MF, Eslin D. Cholinergic manipulation alters stimulus-evoked metabolic activity in cat somatosensory cortex. The Journal of Comparative Neurology. 297: 106-20. PMID 2376628 DOI: 10.1002/cne.902970108  0.378
1990 Barstad KE, Bear MF. Basal forebrain projections to somatosensory cortex in the cat. Journal of Neurophysiology. 64: 1223-32. PMID 2258743 DOI: 10.1152/Jn.1990.64.4.1223  0.327
1990 Feldman D, Sherin JE, Press WA, Bear MF. N-methyl-D-aspartate-evoked calcium uptake by kitten visual cortex maintained in vitro. Experimental Brain Research. 80: 252-9. PMID 2162780 DOI: 10.1007/BF00228153  0.459
1990 Bear MF, Kleinschmidt A, Gu QA, Singer W. Disruption of experience-dependent synaptic modifications in striate cortex by infusion of an NMDA receptor antagonist. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 10: 909-25. PMID 1969466 DOI: 10.1523/Jneurosci.10-03-00909.1990  0.713
1990 Bear MF, Colman H. Binocular competition in the control of geniculate cell size depends upon visual cortical N-methyl-D-aspartate receptor activation. Proceedings of the National Academy of Sciences of the United States of America. 87: 9246-9. PMID 1701255 DOI: 10.1073/Pnas.87.23.9246  0.482
1989 Dudek SM, Bear MF. A biochemical correlate of the critical period for synaptic modification in the visual cortex. Science (New York, N.Y.). 246: 673-5. PMID 2573152 DOI: 10.1126/Science.2573152  0.662
1989 Gu QA, Bear MF, Singer W. Blockade of NMDA-receptors prevents ocularity changes in kitten visual cortex after reversed monocular deprivation. Brain Research. Developmental Brain Research. 47: 281-8. PMID 2568191 DOI: 10.1016/0165-3806(89)90183-1  0.599
1989 Dudek SM, Bowen WD, Bear MF. Postnatal changes in glutamate stimulated phosphoinositide turnover in rat neocortical synaptoneurosomes. Brain Research. Developmental Brain Research. 47: 123-8. PMID 2567641 DOI: 10.1016/0165-3806(89)90114-4  0.593
1989 Neve RL, Bear MF. Visual experience regulates gene expression in the developing striate cortex. Proceedings of the National Academy of Sciences of the United States of America. 86: 4781-4. PMID 2543986 DOI: 10.1073/Pnas.86.12.4781  0.43
1988 Bear MF, Kleinschmidt A, Singer W. Experience-dependent modifications of kitten striate cortex are not prevented by thalamic lesions that include the intralaminar nuclei. Experimental Brain Research. 70: 627-31. PMID 3384061 DOI: 10.1007/BF00247611  0.622
1987 Bear MF, Cooper LN, Ebner FF. A physiological basis for a theory of synapse modification. Science (New York, N.Y.). 237: 42-8. PMID 3037696 DOI: 10.1126/Science.3037696  0.76
1987 Kleinschmidt A, Bear MF, Singer W. Blockade of "NMDA" receptors disrupts experience-dependent plasticity of kitten striate cortex. Science (New York, N.Y.). 238: 355-8. PMID 2443978 DOI: 10.1126/Science.2443978  0.682
1986 Bear MF, Singer W. Modulation of visual cortical plasticity by acetylcholine and noradrenaline. Nature. 320: 172-6. PMID 3005879 DOI: 10.1038/320172a0  0.609
1985 Bear MF, Carnes KM, Ebner FF. An investigation of cholinergic circuitry in cat striate cortex using acetylcholinesterase histochemistry. The Journal of Comparative Neurology. 234: 411-30. PMID 3988993 DOI: 10.1002/cne.902340402  0.562
1985 Bear MF, Carnes KM, Ebner FF. Postnatal changes in the distribution of acetylcholinesterase in kitten striate cortex. The Journal of Comparative Neurology. 237: 519-32. PMID 3900150 DOI: 10.1002/cne.902370408  0.555
1985 Bear MF, Schmechel DE, Ebner FF. Glutamic acid decarboxylase in the striate cortex of normal and monocularly deprived kittens. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 5: 1262-75. PMID 2987436 DOI: 10.1523/Jneurosci.05-05-01262.1985  0.65
1985 Höhmann CF, Bear MF, Ebner FF. Glutamic acid decarboxylase activity decreases in mouse neocortex after lesions of the basal forebrain. Brain Research. 333: 165-8. PMID 2986770 DOI: 10.1016/0006-8993(85)90139-8  0.574
1983 Bear MF, Paradiso MA, Schwartz M, Nelson SB, Carnes KM, Daniels JD. Two methods of catecholamine depletion in kitten visual cortex yield different effects on plasticity. Nature. 302: 245-7. PMID 6835361 DOI: 10.1038/302245a0  0.835
1983 Bear MF, Daniels JD. The plastic response to monocular deprivation persists in kitten visual cortex after chronic depletion of norepinephrine. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 3: 407-16. PMID 6401803 DOI: 10.1523/Jneurosci.03-02-00407.1983  0.739
1983 Bear MF, Ebner FF. Somatostatin-like immunoreactivity in the forebrain of Pseudemys turtles. Neuroscience. 9: 297-307. PMID 6192360 DOI: 10.1016/0306-4522(83)90295-6  0.576
1983 Paradiso MA, Bear MF, Daniels JD. Effects of intracortical infusion of 6-hydroxydopamine on the response of kitten visual cortex to monocular deprivation Experimental Brain Research. 51: 413-422. DOI: 10.1007/BF00237878  0.814
1981 Bear MF, Ebner FF. Somatostatin-like immunoreactivity in the cerebral cortex of the turtle, Pseudemys scripta Anatomical Record. 199: 22A.  0.51
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