| Year |
Citation |
Score |
| 2023 |
Horsthemke B, Bird A. Loss of CpG island immunity to DNA methylation induced by mutation. Epigenetics & Chromatin. 16: 17. PMID 37170330 DOI: 10.1186/s13072-023-00488-5 |
0.377 |
|
| 2022 |
Zlatic SA, Duong D, Gadalla KKE, Murage B, Ping L, Shah R, Fink JJ, Khwaja O, Swanson LC, Sahin M, Rayaprolu S, Kumar P, Rangaraju S, Bird A, Tarquinio D, et al. Convergent cerebrospinal fluid proteomes and metabolic ontologies in humans and animal models of Rett syndrome. Iscience. 25: 104966. PMID 36060065 DOI: 10.1016/j.isci.2022.104966 |
0.553 |
|
| 2021 |
Tillotson R, Cholewa-Waclaw J, Chhatbar K, Connelly JC, Kirschner SA, Webb S, Koerner MV, Selfridge J, Kelly DA, De Sousa D, Brown K, Lyst MJ, Kriaucionis S, Bird A. Neuronal non-CG methylation is an essential target for MeCP2 function. Molecular Cell. PMID 33561390 DOI: 10.1016/j.molcel.2021.01.011 |
0.389 |
|
| 2020 |
Chhatbar K, Cholewa-Waclaw J, Shah R, Bird A, Sanguinetti G. Quantitative analysis questions the role of MeCP2 as a global regulator of alternative splicing. Plos Genetics. 16: e1009087. PMID 33048927 DOI: 10.1371/journal.pgen.1009087 |
0.67 |
|
| 2020 |
Bird A. DNA Methylation: Mega-Year Inheritance with the Help of Darwin. Current Biology : Cb. 30: R319-R321. PMID 32259507 DOI: 10.1016/J.Cub.2020.02.034 |
0.442 |
|
| 2020 |
Connelly JC, Cholewa-Waclaw J, Webb S, Steccanella V, Waclaw B, Bird A. Absence of MeCP2 binding to non-methylated GT-rich sequences in vivo. Nucleic Acids Research. PMID 32064528 DOI: 10.1093/Nar/Gkaa102 |
0.479 |
|
| 2019 |
Bird A. The Selfishness of Law-Abiding Genes. Trends in Genetics : Tig. PMID 31662191 DOI: 10.1016/J.Tig.2019.10.002 |
0.334 |
|
| 2019 |
Tillotson R, Bird A. The Molecular Basis of MeCP2 Function in the Brain. Journal of Molecular Biology. PMID 31629770 DOI: 10.1016/J.Jmb.2019.10.004 |
0.442 |
|
| 2019 |
Cholewa-Waclaw J, Shah R, Webb S, Chhatbar K, Ramsahoye B, Pusch O, Yu M, Greulich P, Waclaw B, Bird AP. Quantitative modelling predicts the impact of DNA methylation on RNA polymerase II traffic. Proceedings of the National Academy of Sciences of the United States of America. PMID 31289233 DOI: 10.1073/Pnas.1903549116 |
0.69 |
|
| 2019 |
Skourti-Stathaki K, Torlai Triglia E, Warburton M, Voigt P, Bird A, Pombo A. R-Loops Enhance Polycomb Repression at a Subset of Developmental Regulator Genes. Molecular Cell. PMID 30709709 DOI: 10.1016/J.Molcel.2018.12.016 |
0.333 |
|
| 2018 |
Koerner MV, FitzPatrick L, Selfridge J, Guy J, De Sousa D, Tillotson R, Kerr A, Sun Z, Lazar MA, Lyst MJ, Bird A. Toxicity of overexpressed MeCP2 is independent of HDAC3 activity. Genes & Development. PMID 30463906 DOI: 10.1101/Gad.320325.118 |
0.408 |
|
| 2018 |
Lyst MJ, Ekiert R, Guy J, Selfridge J, Koerner MV, Merusi C, De Sousa D, Bird A. Affinity for DNA Contributes to NLS Independent Nuclear Localization of MeCP2. Cell Reports. 24: 2213-2220. PMID 30157418 DOI: 10.1016/J.Celrep.2018.07.099 |
0.414 |
|
| 2018 |
Guy J, Alexander-Howden B, FitzPatrick L, DeSousa D, Koerner MV, Selfridge J, Bird A. A mutation-led search for novel functional domains in MeCP2. Human Molecular Genetics. PMID 29718204 DOI: 10.1093/Hmg/Ddy159 |
0.355 |
|
| 2018 |
Antequera F, Bird A. CpG Islands: A Historical Perspective. Methods in Molecular Biology (Clifton, N.J.). 1766: 3-13. PMID 29605844 DOI: 10.1007/978-1-4939-7768-0_1 |
0.42 |
|
| 2017 |
Bird A. Genetic determinants of the epigenome in development and cancer. Swiss Medical Weekly. 147: w14523. PMID 29039625 DOI: 10.4414/Smw.2017.14523 |
0.446 |
|
| 2017 |
Tillotson R, Selfridge J, Koerner MV, Gadalla KKE, Guy J, De Sousa D, Hector RD, Cobb SR, Bird A. Radically truncated MeCP2 rescues Rett syndrome-like neurological defects. Nature. PMID 29019980 DOI: 10.1038/Nature24058 |
0.471 |
|
| 2017 |
Lagger S, Connelly JC, Schweikert G, Webb S, Selfridge J, Ramsahoye BH, Yu M, He C, Sanguinetti G, Sowers LC, Walkinshaw MD, Bird A. MeCP2 recognizes cytosine methylated tri-nucleotide and di-nucleotide sequences to tune transcription in the mammalian brain. Plos Genetics. 13: e1006793. PMID 28498846 DOI: 10.1371/Journal.Pgen.1006793 |
0.516 |
|
| 2017 |
Shah RR, Bird AP. MeCP2 mutations: progress towards understanding and treating Rett syndrome. Genome Medicine. 9: 17. PMID 28212680 DOI: 10.1186/S13073-017-0411-7 |
0.57 |
|
| 2016 |
Ross PD, Guy J, Selfridge J, Kamal B, Bahey N, Tanner KE, Gillingwater TH, Jones RA, Loughrey CM, McCarroll CS, Bailey ME, Bird A, Cobb S. Exclusive expression of MeCP2 in the nervous system distinguishes between brain and peripheral Rett syndrome-like phenotypes. Human Molecular Genetics. 25: 4389-4404. PMID 28173151 DOI: 10.1093/Hmg/Ddw269 |
0.333 |
|
| 2016 |
Shah RR, Cholewa-Waclaw J, Davies FC, Paton KM, Chaligne R, Heard E, Abbott CM, Bird AP. Efficient and versatile CRISPR engineering of human neurons in culture to model neurological disorders. Wellcome Open Research. 1: 13. PMID 27976757 DOI: 10.12688/wellcomeopenres.10011.1 |
0.602 |
|
| 2016 |
Cholewa-Waclaw J, Bird A, von Schimmelmann M, Schaefer A, Yu H, Song H, Madabhushi R, Tsai LH. The Role of Epigenetic Mechanisms in the Regulation of Gene Expression in the Nervous System. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 11427-11434. PMID 27911745 DOI: 10.1523/Jneurosci.2492-16.2016 |
0.424 |
|
| 2016 |
Lyst MJ, Connelly J, Merusi C, Bird A. Sequence specific DNA binding by AT-hook motifs in MeCP2. Febs Letters. PMID 27461740 DOI: 10.1002/1873-3468.12328 |
0.478 |
|
| 2016 |
Quante T, Bird A. Do short, frequent DNA sequence motifs mould the epigenome? Nature Reviews. Molecular Cell Biology. PMID 26837845 DOI: 10.1038/Nrm.2015.31 |
0.451 |
|
| 2016 |
Chhatbar K, Cholewa-Waclaw J, Shah R, Webb S, Waclaw B, Bird A. Integrative analyses of transcriptome and DNA methylome from human neurons expressing multiple MECP2 levels F1000research. 5. DOI: 10.7490/F1000Research.1112954.1 |
0.619 |
|
| 2015 |
Brown K, Selfridge J, Lagger S, Connelly J, De Sousa D, Kerr A, Webb S, Guy J, Merusi C, Koerner MV, Bird A. The molecular basis of variable phenotypic severity among common missense mutations causing Rett syndrome. Human Molecular Genetics. PMID 26647311 DOI: 10.1093/Hmg/Ddv496 |
0.425 |
|
| 2015 |
Cook PC, Owen H, Deaton AM, Borger JG, Brown SL, Clouaire T, Jones GR, Jones LH, Lundie RJ, Marley AK, Morrison VL, Phythian-Adams AT, Wachter E, Webb LM, Sutherland TE, ... ... Bird A, et al. A dominant role for the methyl-CpG-binding protein Mbd2 in controlling Th2 induction by dendritic cells. Nature Communications. 6: 6920. PMID 25908537 DOI: 10.1038/Ncomms7920 |
0.416 |
|
| 2015 |
Lyst MJ, Bird A. Rett syndrome: a complex disorder with simple roots. Nature Reviews. Genetics. 16: 261-75. PMID 25732612 DOI: 10.1038/Nrg3897 |
0.395 |
|
| 2015 |
Grunstein M, Bird A. Max Birnstiel 1933-2014: Gene pioneer. Proceedings of the National Academy of Sciences of the United States of America. 112: 302-3. PMID 25556180 DOI: 10.1073/Pnas.1423755112 |
0.543 |
|
| 2014 |
Wachter E, Quante T, Merusi C, Arczewska A, Stewart F, Webb S, Bird A. Synthetic CpG islands reveal DNA sequence determinants of chromatin structure. Elife. 3: e03397. PMID 25259796 DOI: 10.7554/Elife.03397 |
0.482 |
|
| 2014 |
Clouaire T, Webb S, Bird A. Cfp1 is required for gene expression-dependent H3K4 trimethylation and H3K9 acetylation in embryonic stem cells. Genome Biology. 15: 451. PMID 25201068 DOI: 10.1186/S13059-014-0451-X |
0.405 |
|
| 2014 |
Song C, Feodorova Y, Guy J, Peichl L, Jost KL, Kimura H, Cardoso MC, Bird A, Leonhardt H, Joffe B, Solovei I. DNA methylation reader MECP2: cell type- and differentiation stage-specific protein distribution. Epigenetics & Chromatin. 7: 17. PMID 25170345 DOI: 10.1186/1756-8935-7-17 |
0.436 |
|
| 2014 |
Deaton AM, Cook PC, De Sousa D, Phythian-Adams AT, Bird A, MacDonald AS. A unique DNA methylation signature defines a population of IFN-γ/IL-4 double-positive T cells during helminth infection. European Journal of Immunology. 44: 1835-41. PMID 24578067 DOI: 10.1002/Eji.201344098 |
0.337 |
|
| 2014 |
Wachter E, Quante T, Merusi C, Arczewska A, Stewart F, Webb S, Bird A. Author response: Synthetic CpG islands reveal DNA sequence determinants of chromatin structure Elife. DOI: 10.7554/Elife.03397.017 |
0.394 |
|
| 2014 |
Clouaire T, Webb S, Bird A. Cfp1 is required for gene expression dependent H3K4me3 and H3K9 acetylation in embryonic stem cells Genome Biology. 15: 451. DOI: 10.1186/Preaccept-8577431391252814 |
0.43 |
|
| 2013 |
Suzuki MM, Yoshinari A, Obara M, Takuno S, Shigenobu S, Sasakura Y, Kerr AR, Webb S, Bird A, Nakayama A. Identical sets of methylated and nonmethylated genes in Ciona intestinalis sperm and muscle cells. Epigenetics & Chromatin. 6: 38. PMID 24279449 DOI: 10.1186/1756-8935-6-38 |
0.478 |
|
| 2013 |
Schweikert G, Cseke B, Clouaire T, Bird A, Sanguinetti G. MMDiff: quantitative testing for shape changes in ChIP-Seq data sets. Bmc Genomics. 14: 826. PMID 24267901 DOI: 10.1186/1471-2164-14-826 |
0.388 |
|
| 2013 |
Bird A. Genome biology: not drowning but waving. Cell. 154: 951-2. PMID 23993086 DOI: 10.1016/J.Cell.2013.08.010 |
0.322 |
|
| 2013 |
Garg SK, Lioy DT, Cheval H, McGann JC, Bissonnette JM, Murtha MJ, Foust KD, Kaspar BK, Bird A, Mandel G. Systemic delivery of MeCP2 rescues behavioral and cellular deficits in female mouse models of Rett syndrome. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 13612-20. PMID 23966684 DOI: 10.1523/Jneurosci.1854-13.2013 |
0.33 |
|
| 2013 |
Lyst MJ, Ekiert R, Ebert DH, Merusi C, Nowak J, Selfridge J, Guy J, Kastan NR, Robinson ND, de Lima Alves F, Rappsilber J, Greenberg ME, Bird A. Rett syndrome mutations abolish the interaction of MeCP2 with the NCoR/SMRT co-repressor. Nature Neuroscience. 16: 898-902. PMID 23770565 DOI: 10.1038/Nn.3434 |
0.361 |
|
| 2013 |
McLeod F, Ganley R, Williams L, Selfridge J, Bird A, Cobb SR. Reduced seizure threshold and altered network oscillatory properties in a mouse model of Rett syndrome. Neuroscience. 231: 195-205. PMID 23238573 DOI: 10.1016/J.Neuroscience.2012.11.058 |
0.311 |
|
| 2013 |
Bird A. Epigenetics: What's left to find out New Scientist. 217: viii. DOI: 10.1016/S0262-4079(13)60033-0 |
0.386 |
|
| 2013 |
Bird A. Epigenetics: Far-reaching effects New Scientist. 217: vi-vii. DOI: 10.1016/S0262-4079(13)60032-9 |
0.346 |
|
| 2013 |
Bird A. Epigenetics: A ubiquitous phenomenon New Scientist. 217: iv-v. DOI: 10.1016/S0262-4079(13)60031-7 |
0.341 |
|
| 2012 |
Yazdani M, Deogracias R, Guy J, Poot RA, Bird A, Barde YA. Disease modeling using embryonic stem cells: MeCP2 regulates nuclear size and RNA synthesis in neurons. Stem Cells (Dayton, Ohio). 30: 2128-39. PMID 22865604 DOI: 10.1002/Stem.1180 |
0.368 |
|
| 2012 |
Clouaire T, Webb S, Skene P, Illingworth R, Kerr A, Andrews R, Lee JH, Skalnik D, Bird A. Cfp1 integrates both CpG content and gene activity for accurate H3K4me3 deposition in embryonic stem cells. Genes & Development. 26: 1714-28. PMID 22855832 DOI: 10.1101/Gad.194209.112 |
0.488 |
|
| 2012 |
Cheval H, Guy J, Merusi C, De Sousa D, Selfridge J, Bird A. Postnatal inactivation reveals enhanced requirement for MeCP2 at distinct age windows. Human Molecular Genetics. 21: 3806-14. PMID 22653753 DOI: 10.1093/Hmg/Dds208 |
0.322 |
|
| 2012 |
Robinson L, Guy J, McKay L, Brockett E, Spike RC, Selfridge J, De Sousa D, Merusi C, Riedel G, Bird A, Cobb SR. Morphological and functional reversal of phenotypes in a mouse model of Rett syndrome. Brain : a Journal of Neurology. 135: 2699-710. PMID 22525157 DOI: 10.1093/Brain/Aws096 |
0.316 |
|
| 2011 |
Bird A. Putting the DNA back into DNA methylation. Nature Genetics. 43: 1050-1. PMID 22030606 DOI: 10.1038/Ng.987 |
0.464 |
|
| 2011 |
Guy J, Cheval H, Selfridge J, Bird A. The role of MeCP2 in the brain. Annual Review of Cell and Developmental Biology. 27: 631-52. PMID 21721946 DOI: 10.1146/Annurev-Cellbio-092910-154121 |
0.474 |
|
| 2011 |
Deaton AM, Webb S, Kerr AR, Illingworth RS, Guy J, Andrews R, Bird A. Cell type-specific DNA methylation at intragenic CpG islands in the immune system. Genome Research. 21: 1074-86. PMID 21628449 DOI: 10.1101/Gr.118703.110 |
0.421 |
|
| 2011 |
Deaton AM, Bird A. CpG islands and the regulation of transcription. Genes & Development. 25: 1010-22. PMID 21576262 DOI: 10.1101/Gad.2037511 |
0.501 |
|
| 2011 |
Bird A. The dinucleotide CG as a genomic signalling module. Journal of Molecular Biology. 409: 47-53. PMID 21295585 DOI: 10.1186/1756-8935-6-S1-O6 |
0.488 |
|
| 2011 |
Cortázar D, Kunz C, Selfridge J, Lettieri T, Saito Y, MacDougall E, Wirz A, Schuermann D, Jacobs AL, Siegrist F, Steinacher R, Jiricny J, Bird A, Schär P. Embryonic lethal phenotype reveals a function of TDG in maintaining epigenetic stability. Nature. 470: 419-23. PMID 21278727 DOI: 10.1038/Nature09672 |
0.506 |
|
| 2010 |
Illingworth RS, Gruenewald-Schneider U, Webb S, Kerr AR, James KD, Turner DJ, Smith C, Harrison DJ, Andrews R, Bird AP. Orphan CpG islands identify numerous conserved promoters in the mammalian genome. Plos Genetics. 6: e1001134. PMID 20885785 DOI: 10.1371/Journal.Pgen.1001134 |
0.392 |
|
| 2010 |
Thomson JP, Skene PJ, Selfridge J, Clouaire T, Guy J, Webb S, Kerr AR, Deaton A, Andrews R, James KD, Turner DJ, Illingworth R, Bird A. CpG islands influence chromatin structure via the CpG-binding protein Cfp1. Nature. 464: 1082-6. PMID 20393567 DOI: 10.1038/Nature08924 |
0.514 |
|
| 2010 |
Athanasiadou R, de Sousa D, Myant K, Merusi C, Stancheva I, Bird A. Targeting of de novo DNA methylation throughout the Oct-4 gene regulatory region in differentiating embryonic stem cells. Plos One. 5: e9937. PMID 20376339 DOI: 10.1371/Journal.Pone.0009937 |
0.495 |
|
| 2010 |
Cobb S, Guy J, Bird A. Reversibility of functional deficits in experimental models of Rett syndrome. Biochemical Society Transactions. 38: 498-506. PMID 20298210 DOI: 10.1042/Bst0380498 |
0.325 |
|
| 2010 |
Skene PJ, Illingworth RS, Webb S, Kerr AR, James KD, Turner DJ, Andrews R, Bird AP. Neuronal MeCP2 is expressed at near histone-octamer levels and globally alters the chromatin state. Molecular Cell. 37: 457-68. PMID 20188665 DOI: 10.1016/j.molcel.2010.01.030 |
0.392 |
|
| 2009 |
Illingworth RS, Bird AP. CpG islands--'a rough guide'. Febs Letters. 583: 1713-20. PMID 19376112 DOI: 10.1016/j.febslet.2009.04.012 |
0.42 |
|
| 2008 |
Martin V, Jørgensen HF, Chaubert AS, Berger J, Barr H, Shaw P, Bird A, Chaubert P. MBD2-mediated transcriptional repression of the p14ARF tumor suppressor gene in human colon cancer cells. Pathobiology : Journal of Immunopathology, Molecular and Cellular Biology. 75: 281-7. PMID 18931530 DOI: 10.1159/000151708 |
0.406 |
|
| 2008 |
Bird A. The methyl-CpG-binding protein MeCP2 and neurological disease. Biochemical Society Transactions. 36: 575-83. PMID 18631120 DOI: 10.1042/Bst0360575 |
0.551 |
|
| 2008 |
Suzuki MM, Bird A. DNA methylation landscapes: provocative insights from epigenomics. Nature Reviews. Genetics. 9: 465-76. PMID 18463664 DOI: 10.1038/Nrg2341 |
0.511 |
|
| 2008 |
Ho KL, McNae IW, Schmiedeberg L, Klose RJ, Bird AP, Walkinshaw MD. MeCP2 binding to DNA depends upon hydration at methyl-CpG. Molecular Cell. 29: 525-31. PMID 18313390 DOI: 10.1016/j.molcel.2007.12.028 |
0.378 |
|
| 2008 |
Illingworth R, Kerr A, DeSousa D, Jørgensen H, Ellis P, Stalker J, Jackson D, Clee C, Plumb R, Rogers J, Humphray S, Cox T, Langford C, Bird A. A novel CpG island set identifies tissue-specific methylation at developmental gene loci Plos Biology. 6: 0037-0051. PMID 18232738 DOI: 10.1371/Journal.Pbio.0060022 |
0.502 |
|
| 2007 |
Bird A. Perceptions of epigenetics. Nature. 447: 396-8. PMID 17522671 DOI: 10.1038/Nature05913 |
0.347 |
|
| 2007 |
Suzuki MM, Kerr AR, De Sousa D, Bird A. CpG methylation is targeted to transcription units in an invertebrate genome. Genome Research. 17: 625-31. PMID 17420183 DOI: 10.1101/Gr.6163007 |
0.522 |
|
| 2007 |
Barr H, Hermann A, Berger J, Tsai HH, Adie K, Prokhortchouk A, Hendrich B, Bird A. Mbd2 contributes to DNA methylation-directed repression of the Xist gene. Molecular and Cellular Biology. 27: 3750-7. PMID 17353271 DOI: 10.1128/Mcb.02204-06 |
0.539 |
|
| 2007 |
Berger J, Sansom O, Clarke A, Bird A. MBD2 is required for correct spatial gene expression in the gut. Molecular and Cellular Biology. 27: 4049-57. PMID 17353267 DOI: 10.1128/Mcb.02023-06 |
0.47 |
|
| 2007 |
Nan X, Hou J, Maclean A, Nasir J, Lafuente MJ, Shu X, Kriaucionis S, Bird A. Interaction between chromatin proteins MECP2 and ATRX is disrupted by mutations that cause inherited mental retardation. Proceedings of the National Academy of Sciences of the United States of America. 104: 2709-14. PMID 17296936 DOI: 10.1073/Pnas.0608056104 |
0.458 |
|
| 2007 |
Guy J, Gan J, Selfridge J, Cobb S, Bird A. Reversal of neurological defects in a mouse model of Rett syndrome. Science (New York, N.Y.). 315: 1143-7. PMID 17289941 DOI: 10.1126/Science.1138389 |
0.315 |
|
| 2006 |
Jørgensen HF, Adie K, Chaubert P, Bird AP. Engineering a high-affinity methyl-CpG-binding protein. Nucleic Acids Research. 34: e96. PMID 16893950 DOI: 10.1093/nar/gkl527 |
0.38 |
|
| 2006 |
Kriaucionis S, Paterson A, Curtis J, Guy J, Macleod N, Bird A. Gene expression analysis exposes mitochondrial abnormalities in a mouse model of Rett syndrome. Molecular and Cellular Biology. 26: 5033-42. PMID 16782889 DOI: 10.1128/Mcb.01665-05 |
0.388 |
|
| 2006 |
Klose RJ, Bird AP. Genomic DNA methylation: the mark and its mediators. Trends in Biochemical Sciences. 31: 89-97. PMID 16403636 DOI: 10.1016/j.tibs.2005.12.008 |
0.438 |
|
| 2006 |
Prokhortchouk A, Sansom O, Selfridge J, Caballero IM, Salozhin S, Aithozhina D, Cerchietti L, Meng FG, Augenlicht LH, Mariadason JM, Hendrich B, Melnick A, Prokhortchouk E, Clarke A, Bird A. Kaiso-deficient mice show resistance to intestinal cancer. Molecular and Cellular Biology. 26: 199-208. PMID 16354691 DOI: 10.1128/Mcb.26.1.199-208.2006 |
0.361 |
|
| 2005 |
Berger J, Bird A. Role of MBD2 in gene regulation and tumorigenesis Biochemical Society Transactions. 33: 1537-1540. PMID 16246164 DOI: 10.1042/Bst20051537 |
0.537 |
|
| 2005 |
Suzuki MM, Nishikawa T, Bird A. Genomic approaches reveal unexpected genetic divergence within Ciona intestinalis. Journal of Molecular Evolution. 61: 627-35. PMID 16205978 DOI: 10.1007/S00239-005-0009-3 |
0.309 |
|
| 2005 |
Klose RJ, Sarraf SA, Schmiedeberg L, McDermott SM, Stancheva I, Bird AP. DNA binding selectivity of MeCP2 due to a requirement for A/T sequences adjacent to methyl-CpG Molecular Cell. 19: 667-678. PMID 16137622 DOI: 10.1016/j.molcel.2005.07.021 |
0.387 |
|
| 2005 |
Nuber UA, Kriaucionis S, Roloff TC, Guy J, Selfridge J, Steinhoff C, Schulz R, Lipkowitz B, Ropers HH, Holmes MC, Bird A. Up-regulation of glucocorticoid-regulated genes in a mouse model of Rett syndrome. Human Molecular Genetics. 14: 2247-56. PMID 16002417 DOI: 10.1093/Hmg/Ddi229 |
0.42 |
|
| 2005 |
Sansom OJ, Bishop SM, Bird A, Clarke AR. MBD2 deficiency does not accelerate p53 mediated lymphomagenesis. Oncogene. 24: 2430-2. PMID 15735763 DOI: 10.1038/Sj.Onc.1208166 |
0.427 |
|
| 2004 |
Bird A, Macleod D. Reading the DNA methylation signal. Cold Spring Harbor Symposia On Quantitative Biology. 69: 113-118. PMID 16117639 DOI: 10.1101/Sqb.2004.69.113 |
0.431 |
|
| 2004 |
Valinluck V, Tsai HH, Rogstad DK, Burdzy A, Bird A, Sowers LC. Oxidative damage to methyl-CpG sequences inhibits the binding of the methyl-CpG binding domain (MBD) of methyl-CpG binding protein 2 (MeCP2). Nucleic Acids Research. 32: 4100-8. PMID 15302911 DOI: 10.1093/Nar/Gkh739 |
0.495 |
|
| 2004 |
Sansom OJ, Bishop SM, Bird A, Clarke AR. MBD4 deficiency does not increase mutation or accelerate tumorigenesis in mice lacking MMR. Oncogene. 23: 5693-6. PMID 15184874 DOI: 10.1038/Sj.Onc.1207767 |
0.338 |
|
| 2004 |
Beaujean N, Taylor JE, McGarry M, Gardner JO, Wilmut I, Loi P, Ptak G, Galli C, Lazzari G, Bird A, Young LE, Meehan RR. The effect of interspecific oocytes on demethylation of sperm DNA. Proceedings of the National Academy of Sciences of the United States of America. 101: 7636-40. PMID 15136736 DOI: 10.1073/Pnas.0400730101 |
0.414 |
|
| 2004 |
Jørgensen HF, Ben-Porath I, Bird AP. Mbd1 is recruited to both methylated and nonmethylated CpGs via distinct DNA binding domains. Molecular and Cellular Biology. 24: 3387-95. PMID 15060159 |
0.395 |
|
| 2004 |
Kriaucionis S, Bird A. The major form of MeCP2 has a novel N-terminus generated by alternative splicing. Nucleic Acids Research. 32: 1818-23. PMID 15034150 DOI: 10.1093/Nar/Gkh349 |
0.431 |
|
| 2003 |
Sansom OJ, Zabkiewicz J, Bishop SM, Guy J, Bird A, Clarke AR. MBD4 deficiency reduces the apoptotic response to DNA-damaging agents in the murine small intestine. Oncogene. 22: 7130-6. PMID 14562041 DOI: 10.1038/Sj.Onc.1206850 |
0.377 |
|
| 2003 |
Kriaucionis S, Bird A. DNA methylation and Rett syndrome. Human Molecular Genetics. 12: R221-7. PMID 12928486 DOI: 10.1093/Hmg/Ddg286 |
0.507 |
|
| 2003 |
Bader S, Walker M, McQueen HA, Sellar R, Oei E, Wopereis S, Zhu Y, Peter A, Bird AP, Harrison DJ. MBD1, MBD2 and CGBP genes at chromosome 18q21 are infrequently mutated in human colon and lung cancers. Oncogene. 22: 3506-10. PMID 12776203 DOI: 10.1038/sj.onc.1206574 |
0.318 |
|
| 2003 |
Sansom OJ, Berger J, Bishop SM, Hendrich B, Bird A, Clarke AR. Deficiency of Mbd2 suppresses intestinal tumorigenesis. Nature Genetics. 34: 145-7. PMID 12730693 DOI: 10.1038/Ng1155 |
0.428 |
|
| 2003 |
Selker EU, Tountas NA, Cross SH, Margolin BS, Murphy JG, Bird AP, Freitag M. The methylated component of the Neurospora crassa genome. Nature. 422: 893-7. PMID 12712205 DOI: 10.1038/Nature01564 |
0.397 |
|
| 2003 |
Screaton RA, Kiessling S, Sansom OJ, Millar CB, Maddison K, Bird A, Clarke AR, Frisch SM. Fas-associated death domain protein interacts with methyl-CpG binding domain protein 4: a potential link between genome surveillance and apoptosis. Proceedings of the National Academy of Sciences of the United States of America. 100: 5211-6. PMID 12702765 DOI: 10.1073/Pnas.0431215100 |
0.382 |
|
| 2003 |
Jaenisch R, Bird A. Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals. Nature Genetics. 33: 245-54. PMID 12610534 DOI: 10.1038/Ng1089 |
0.501 |
|
| 2003 |
Bird A. Il2 transcription unleashed by active DNA demethylation. Nature Immunology. 4: 208-9. PMID 12605226 DOI: 10.1038/Ni0303-208 |
0.387 |
|
| 2003 |
Fuks F, Hurd PJ, Wolf D, Nan X, Bird AP, Kouzarides T. The methyl-CpG-binding protein MeCP2 links DNA methylation to histone methylation Journal of Biological Chemistry. 278: 4035-4040. PMID 12427740 DOI: 10.1074/Jbc.M210256200 |
0.408 |
|
| 2002 |
Hutchins AS, Mullen AC, Lee HW, Sykes KJ, High FA, Hendrich BD, Bird AP, Reiner SL. Gene silencing quantitatively controls the function of a developmental trans-activator. Molecular Cell. 10: 81-91. PMID 12150909 DOI: 10.1016/S1097-2765(02)00564-6 |
0.347 |
|
| 2002 |
Millar CB, Guy J, Sansom OJ, Selfridge J, MacDougall E, Hendrich B, Keightley PD, Bishop SM, Clarke AR, Bird A. Enhanced CpG mutability and tumorigenesis in MBD4-deficient mice. Science (New York, N.Y.). 297: 403-5. PMID 12130785 DOI: 10.1126/Science.1073354 |
0.414 |
|
| 2002 |
Jørgensen HF, Bird A. MeCP2 and other methyl-CpG binding proteins. Mental Retardation and Developmental Disabilities Research Reviews. 8: 87-93. PMID 12112733 DOI: 10.1002/Mrdd.10021 |
0.526 |
|
| 2002 |
Bird A. DNA methylation patterns and epigenetic memory Genes and Development. 16: 6-21. PMID 11782440 DOI: 10.1101/Gad.947102 |
0.527 |
|
| 2001 |
Nan X, Bird A. The biological functions of the methyl-CpG-binding protein MeCP2 and its implication in Rett syndrome. Brain & Development. 23. PMID 11738839 DOI: 10.1016/S0387-7604(01)00333-3 |
0.548 |
|
| 2001 |
Prokhortchouk A, Hendrich B, Jørgensen H, Ruzov A, Wilm M, Georgiev G, Bird A, Prokhortchouk E. The p120 catenin partner Kaiso is a DNA methylation-dependent transcriptional repressor Genes & Development. 15: 1613-1618. PMID 11445535 DOI: 10.1101/Gad.198501 |
0.519 |
|
| 2001 |
Barlow AL, van Drunen CM, Johnson CA, Tweedie S, Bird A, Turner BM. dSIR2 and dHDAC6: two novel, inhibitor-resistant deacetylases in Drosophila melanogaster. Experimental Cell Research. 265: 90-103. PMID 11281647 DOI: 10.1006/Excr.2001.5162 |
0.337 |
|
| 2001 |
Hendrich B, Guy J, Ramsahoye B, Wilson VA, Bird A. Closely related proteins MBD2 and MBD3 play distinctive but interacting roles in mouse development. Genes & Development. 15: 710-23. PMID 11274056 DOI: 10.1101/Gad.194101 |
0.476 |
|
| 2000 |
Tweedie S, Bird A. Gene expression. Mutant weed breaks silence. Nature. 405: 137-138. PMID 10821258 DOI: 10.1038/35012200 |
0.491 |
|
| 2000 |
Ng HH, Bird A. Histone deacetylases: silencers for hire. Trends in Biochemical Sciences. 25: 121-126. PMID 10694882 DOI: 10.1016/S0968-0004(00)01551-6 |
0.392 |
|
| 2000 |
Ng H, Jeppesen P, Bird A. Active repression of methylated genes by the chromosomal protein MBD1. Molecular and Cellular Biology. 20: 1394-1406. PMID 10648624 DOI: 10.1128/Mcb.20.4.1394-1406.2000 |
0.49 |
|
| 2000 |
Hendrich B, Ng H, Guy J, Bird A. Functional Studies of Proteins that bind to Methylated DNA Biochemical Society Transactions. 28. DOI: 10.1042/Bst028A113C |
0.467 |
|
| 1999 |
Bader S, Walker M, Hendrich B, Bird A, Bird C, Hooper M, Wyllie A. Somatic frameshift mutations in the MBD4 gene of sporadic colon cancers with mismatch repair deficiency. Oncogene. 18: 8044-8047. PMID 10637515 DOI: 10.1038/Sj.Onc.1203229 |
0.366 |
|
| 1999 |
Bird A. DNA Methylation de Novo Science. 286: 2287-2288. PMID 10636791 DOI: 10.1126/Science.286.5448.2287 |
0.485 |
|
| 1999 |
Brock GJR, Charlton J, Bird A. Densely methylated sequences that are preferentially localized at telomere-proximal regions of human chromosomes. Gene. 240: 269-277. PMID 10580146 DOI: 10.1016/S0378-1119(99)00442-4 |
0.483 |
|
| 1999 |
Antequera F, Bird A. CpG islands as genomic footprints of promoters that are associated with replication origins Current Biology. 9. PMID 10508580 DOI: 10.1016/S0960-9822(99)80418-7 |
0.489 |
|
| 1999 |
Hendrich B, Hardeland U, Ng H, Jiricny J, Bird A. The thymine glycosylase MBD4 can bind to the product of deamination at methylated CpG sites Nature. 401: 301-304. PMID 10499592 DOI: 10.1038/45843 |
0.474 |
|
| 1999 |
Zhang Y, Ng HH, Erdjument-Bromage H, Tempst P, Bird A, Reinberg D. Analysis of the NuRD subunits reveals a histone deacetylase core complex and a connection with DNA methylation. Genes & Development. 13: 1924-35. PMID 10444591 DOI: 10.1101/Gad.13.15.1924 |
0.454 |
|
| 1999 |
Hendrich B, Abbott C, McQueen H, Chambers D, Cross S, Bird A. Genomic structure and chromosomal mapping of the murine and human Mbd1, Mbd2, Mbd3, and Mbd4 genes. Mammalian Genome. 10: 906-912. PMID 10441743 DOI: 10.1007/S003359901112 |
0.442 |
|
| 1999 |
Simmen MW, Leitgeb S, Charlton J, Jones SJM, Harris BR, Clark VH, Bird A. Nonmethylated transposable elements and methylated genes in a chordate genome Science. 283: 1164-1167. PMID 10024242 DOI: 10.1126/Science.283.5405.1164 |
0.469 |
|
| 1999 |
Wakefield R, Smith B, Nan X, Free A, Soteriou A, Uhrin D, Bird A, Barlow P. Sequence Specific 1H, 13C and 15N Assignment of the Methyl Binding Domain of the Methyl-CpG-binding Protein MeCP2. Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.13018/Bmr4280 |
0.408 |
|
| 1998 |
Hendrich B, Bird A. Identification and characterization of a family of mammalian methyl-CpG binding proteins. Molecular and Cellular Biology. 18: 6538-6547. PMID 9774669 DOI: 10.1128/Mcb.18.11.6538 |
0.568 |
|
| 1998 |
Macleod D, Ali RR, Bird A. An alternative promoter in the mouse major histocompatibility complex class II I-Abeta gene: implications for the origin of CpG islands. Molecular and Cellular Biology. 18: 4433-43. PMID 9671453 DOI: 10.1128/Mcb.18.8.4433 |
0.431 |
|
| 1998 |
Nan X, Ng HH, Johnson CA, Laherty CD, Turner BM, Eisenman RN, Bird A. Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex. Nature. 393: 386-9. PMID 9620804 DOI: 10.1038/30764 |
0.526 |
|
| 1998 |
Nan X, Cross S, Bird A. Gene silencing by methyl-CpG-binding proteins. Novartis Foundation Symposium. 214: 6-21. PMID 9601009 DOI: 10.1002/9780470515501.Ch2 |
0.512 |
|
| 1998 |
Delgado S, Gómez M, Bird A, Antequera F. Initiation of DNA replication at CpG islands in mammalian chromosomes Embo Journal. 17: 2426-2435. PMID 9545253 DOI: 10.1093/Emboj/17.8.2426 |
0.481 |
|
| 1998 |
Simmen MW, Leitgeb S, Clark VH, Jones SJM, Bird A. Gene number in an invertebrate chordate, Ciona intestinalis Proceedings of the National Academy of Sciences of the United States of America. 95: 4437-4440. PMID 9539755 DOI: 10.1073/Pnas.95.8.4437 |
0.349 |
|
| 1998 |
Hendrich B, Bird A. Identification and characterization of a family of mammalian methyl CpG-binding proteins Genetics Research. 72: 59-72. DOI: 10.1017/S0016672398533307 |
0.394 |
|
| 1997 |
Bird A. Does DNA methylation control transposition of selfish elements in the germline? Trends in Genetics : Tig. 13: 469-472. PMID 9433135 DOI: 10.1016/S0168-9525(97)01310-3 |
0.433 |
|
| 1997 |
Cross SH, Meehan RR, Nan X, Bird A. A component of the transcriptional repressor MeCP1 shares a motif with DNA methyltransferase and HRX proteins. Nature Genetics. 16: 256-259. PMID 9207790 DOI: 10.1038/Ng0797-256 |
0.525 |
|
| 1997 |
Brock GJR, Bird A. Mosaic methylation of the repeat unit of the human ribosomal RNA genes Human Molecular Genetics. 6: 451-456. PMID 9147649 DOI: 10.1093/Hmg/6.3.451 |
0.496 |
|
| 1997 |
Nan X, Campoy FJ, Bird A. MeCP2 Is a Transcriptional Repressor with Abundant Binding Sites in Genomic Chromatin Cell. 88: 471-481. PMID 9038338 DOI: 10.1016/S0092-8674(00)81887-5 |
0.496 |
|
| 1997 |
Tweedie S, Charlton J, Clark V, Bird A. Methylation of genomes and genes at the invertebrate-vertebrate boundary. Molecular and Cellular Biology. 17: 1469-1475. PMID 9032274 DOI: 10.1128/Mcb.17.3.1469 |
0.482 |
|
| 1996 |
Tate P, Skarnes W, Bird A. The methyl-CpG binding protein MeCP2 is essential for embryonic development in the mouse Nature Genetics. 12: 205-208. PMID 8563762 DOI: 10.1038/Ng0296-205 |
0.521 |
|
| 1996 |
Nan X, Tate P, Li E, Bird A. DNA methylation specifies chromosomal localization of MeCP2 Molecular and Cellular Biology. 16: 414-421. PMID 8524323 DOI: 10.1128/Mcb.16.1.414 |
0.498 |
|
| 1995 |
Bird A, Tate P, Nan X, Campoy J, Meehan R, Cross S, Tweedie S, Charlton J, Macleod D. Studies of DNA methylation in animals Journal of Cell Science. 1995: 37-39. PMID 8655645 DOI: 10.1242/Jcs.1995.Supplement_19.5 |
0.512 |
|
| 1995 |
Campoy FJ, Meehan RR, McKay S, Nixon J, Bird A. Binding of Histone H1 to DNA Is Indifferent to Methylation at CpG Sequences Journal of Biological Chemistry. 270: 26473-26481. PMID 7592864 DOI: 10.1074/Jbc.270.44.26473 |
0.49 |
|
| 1993 |
Nan X, Meehan RR, Bird A. Dissection of the methyl-CpG binding domain from the chromosomal protein MeCP2 Nucleic Acids Research. 21: 4886-4892. PMID 8177735 DOI: 10.1093/Nar/21.21.4886 |
0.481 |
|
| 1993 |
Antequera F, Bird A. Number of CpG islands and genes in human and mouse Proceedings of the National Academy of Sciences of the United States of America. 90: 11995-11999. PMID 7505451 DOI: 10.1073/Pnas.90.24.11995 |
0.459 |
|
| 1993 |
Meehan R, Lewis J, Cross S, Nan X, Jeppesen P, Bird A. Transcriptional repression by methylation of CpG. Journal of Cell Science. Supplement. 16: 9-14. PMID 1297654 DOI: 10.1242/Jcs.1992.Supplement_16.2 |
0.507 |
|
| 1992 |
Lewis JD, Meehan RR, Henzel WJ, Maurer-Fogy I, Jeppesen P, Klein F, Bird A. Purification, sequence, and cellular localization of a novel chromosomal protein that binds to Methylated DNA Cell. 69: 905-914. PMID 1606614 DOI: 10.1016/0092-8674(92)90610-O |
0.518 |
|
| 1992 |
Bird A. The essentials of DNA methylation Cell. 70: 5-8. PMID 1377983 DOI: 10.1016/0092-8674(92)90526-I |
0.475 |
|
| 1992 |
Boyes J, Bird A. Repression of genes by DNA methylation depends on CpG density and promoter strength: evidence for involvement of a methyl-CpG binding protein. The Embo Journal. 11: 327-333. DOI: 10.1002/J.1460-2075.1992.Tb05055.X |
0.506 |
|
| 1991 |
Cross S, Kovarik P, Schmidtke J, Bird A. Non-methylated islands in fish genomes are GC-poor Nucleic Acids Research. 19: 1469-1474. PMID 2027755 DOI: 10.1093/Nar/19.7.1469 |
0.44 |
|
| 1991 |
Boyes J, Bird A. DNA methylation inhibits transcription indirectly via a methyl-CpG binding protein Cell. 64: 1123-1134. PMID 2004419 DOI: 10.1016/0092-8674(91)90267-3 |
0.508 |
|
| 1991 |
Lewis J, Bird A. DNA methylation and chromatin structure. Febs Letters. 285: 155-159. PMID 1855583 DOI: 10.1016/0014-5793(91)80795-5 |
0.523 |
|
| 1990 |
Sved J, Bird A. The expected equilibrium of the CpG dinucleotide in vertebrate genomes under a mutation model. Proceedings of the National Academy of Sciences of the United States of America. 87: 4692-6. PMID 2352943 DOI: 10.1073/Pnas.87.12.4692 |
0.374 |
|
| 1990 |
Tazi J, Bird A. Alternative chromatin structure at CpG islands. Cell. 60: 909-920. PMID 2317863 DOI: 10.1016/0092-8674(90)90339-G |
0.385 |
|
| 1990 |
Antequera F, Boyes J, Bird A. High levels of de novo methylation and altered chromatin structure at CpG islands in cell lines. Cell. 62: 503-514. PMID 1974172 DOI: 10.1016/0092-8674(90)90015-7 |
0.458 |
|
| 1987 |
Lavia P, Macleod D, Bird A. Coincident start sites for divergent transcripts at a randomly selected CpG-rich island of mouse. The Embo Journal. 6: 2773-2779. DOI: 10.1002/J.1460-2075.1987.Tb02572.X |
0.438 |
|
| 1985 |
Bird A, Taggart M, Frommer M, Miller OJ, Macleod D. A fraction of the mouse genome that is derived from islands of nonmethylated, CpG-rich DNA Cell. 40: 91-99. PMID 2981636 DOI: 10.1016/0092-8674(85)90312-5 |
0.424 |
|
| 1983 |
Macleod D, Bird A. Transcription in oocytes of highly methylated rDNA from Xenopus laevis sperm. Nature. 306: 200-203. PMID 6646203 DOI: 10.1038/306200A0 |
0.442 |
|
| 1983 |
McStay B, Bird A. The origin of the rRNA precursor from Xenopus borealis, analysed in vivo and in vitro Nucleic Acids Research. 11: 8167-8181. PMID 6324076 DOI: 10.1093/Nar/11.23.8167 |
0.353 |
|
| 1983 |
Volpe AL, Taggart M, McStay B, Bird A. DNaseI-hypersensitive sites at promoter-like sequences in the spacer of Xenopus laevis and Xenopus borealis ribosomal DNA. Nucleic Acids Research. 11: 5361-5380. PMID 6310495 DOI: 10.1093/Nar/11.16.5361 |
0.365 |
|
| 1983 |
Volpe AL, Taggart M, Macleod D, Bird A. Coupled demethylation of sites in a conserved sequence of Xenopus ribosomal DNA. Cold Spring Harbor Symposia On Quantitative Biology. 47: 585-592. PMID 6305578 DOI: 10.1101/Sqb.1983.047.01.069 |
0.438 |
|
| 1982 |
Macleod D, Bird A. DNAase I sensitivity and methylation of active versus inactive rRNA genes in Xenopus species hybrids Cell. 29: 211-218. PMID 6286140 DOI: 10.1016/0092-8674(82)90105-2 |
0.477 |
|
| 1981 |
Bird A, Taggart M, Macleod D. Loss of rDNA methylation accompanies the onset of ribosomal gene activity in early development of X. laevis Cell. 26: 381-390. PMID 6276014 DOI: 10.1016/0092-8674(81)90207-5 |
0.451 |
|
| 1974 |
Rochaix J, Bird A, Bakken A. Ribosomal RNA gene amplification by rolling circles Journal of Molecular Biology. 87: 473-487. PMID 4444033 DOI: 10.1016/0022-2836(74)90098-9 |
0.323 |
|
| 1973 |
Bird A, Rogers E, Birnstiel M. Is gene amplification RNA-directed? Nature: New Biology. 242: 226-30. PMID 4121991 DOI: 10.1038/Newbio242226A0 |
0.538 |
|
| 1971 |
Jacob J, Todd K, Birnstiel ML, Bird A. Molecular hybridization of 3H-labelled ribosomal RNA with DNA in ultrathin sections prepared for electron microscopy Bba Section Nucleic Acids and Protein Synthesis. 228: 761-766. PMID 5572613 DOI: 10.1016/0005-2787(71)90746-5 |
0.559 |
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