| Year |
Citation |
Score |
| 2023 |
Czimmerer Z, Nagy L. Epigenomic regulation of macrophage polarization: Where do the nuclear receptors belong? Immunological Reviews. PMID 37074820 DOI: 10.1111/imr.13209 |
0.349 |
|
| 2023 |
Rehó B, Fadel L, Brazda P, Benziane A, Hegedüs É, Sen P, Gadella TWJ, Tóth K, Nagy L, Vámosi G. Agonist-controlled competition of RAR and VDR nuclear receptors for heterodimerization with RXR is manifested in their DNA-binding. The Journal of Biological Chemistry. 102896. PMID 36639026 DOI: 10.1016/j.jbc.2023.102896 |
0.725 |
|
| 2022 |
Melo N, Belyaeva OV, Berger WK, Halasz L, Yu J, Pilli N, Yang Z, Klyuyeva AV, Elmets C, Atigadda V, Muccio DD, Kane MA, Nagy L, Kedishvili NY, Renfrow MB. Next-generation retinoid X receptor agonists increase ATRA signaling in organotypic epithelium cultures and have distinct effects on receptor dynamics. The Journal of Biological Chemistry. 102746. PMID 36436565 DOI: 10.1016/j.jbc.2022.102746 |
0.328 |
|
| 2020 |
Czimmerer Z, Halasz L, Nagy L. Unorthodox Transcriptional Mechanisms of Lipid-Sensing Nuclear Receptors in Macrophages: Are We Opening a New Chapter? Frontiers in Endocrinology. 11: 609099. PMID 33362723 DOI: 10.3389/fendo.2020.609099 |
0.352 |
|
| 2020 |
Nagy G, Nagy L. Motif grammar: The basis of the language of gene expression. Computational and Structural Biotechnology Journal. 18: 2026-2032. PMID 32802274 DOI: 10.1016/J.Csbj.2020.07.007 |
0.367 |
|
| 2020 |
Fadel L, Rehó B, Volkó J, Bojcsuk D, Kolostyák Z, Nagy G, Müller G, Simándi Z, Hegedüs É, Szabó G, Tóth K, Nagy L, Vámosi G. Agonist binding directs dynamic competition among nuclear receptors for heterodimerization with retinoid X receptor. The Journal of Biological Chemistry. PMID 32513869 DOI: 10.1074/Jbc.Ra119.011614 |
0.407 |
|
| 2020 |
Sansbury BE, Li X, Wong B, Patsalos A, Giannakis N, Zhang MJ, Nagy L, Spite M. Myeloid ALX/FPR2 regulates vascularization following tissue injury. Proceedings of the National Academy of Sciences of the United States of America. PMID 32513697 DOI: 10.1073/Pnas.1918163117 |
0.325 |
|
| 2020 |
Nagy G, Daniel B, Cuaranta-Monroy I, Nagy L. Unraveling the hierarchy of and factors that determine the DNA binding by PPARγ. Molecular and Cellular Biology. PMID 31932484 DOI: 10.1128/Mcb.00547-19 |
0.373 |
|
| 2019 |
Rehó B, Lau L, Mocsár G, Müller G, Fadel L, Brazda P, Nagy L, Toth K, Vámosi G. Simultaneous mapping of molecular proximity and co-mobility reveals agonist-enhanced dimerization and DNA binding of nuclear receptors. Analytical Chemistry. PMID 31870146 DOI: 10.1021/Acs.Analchem.9B04902 |
0.75 |
|
| 2019 |
Patsalos A, Tzerpos P, Halasz L, Nagy G, Pap A, Giannakis N, Lyroni K, Koliaraki V, Pintye E, Dezso B, Kollias G, Spilianakis CG, Nagy L. The BACH1-HMOX1 Regulatory Axis Is Indispensable for Proper Macrophage Subtype Specification and Skeletal Muscle Regeneration. Journal of Immunology (Baltimore, Md. : 1950). PMID 31405954 DOI: 10.4049/Jimmunol.1900553 |
0.353 |
|
| 2019 |
Piaszyk-Borychowska A, Széles L, Csermely A, Chiang HC, Wesoły J, Lee CK, Nagy L, Bluyssen HAR. Signal Integration of IFN-I and IFN-II With TLR4 Involves Sequential Recruitment of STAT1-Complexes and NFκB to Enhance Pro-inflammatory Transcription. Frontiers in Immunology. 10: 1253. PMID 31231385 DOI: 10.3389/Fimmu.2019.01253 |
0.395 |
|
| 2019 |
Smith DG, Martinelli R, Besra GS, Illarionov PA, Szatmari I, Brazda P, Allen MA, Xu W, Wang X, Nagy L, Dowell RD, Rook GAW, Rosa Brunet L, Lowry CA. Identification and characterization of a novel anti-inflammatory lipid isolated from Mycobacterium vaccae, a soil-derived bacterium with immunoregulatory and stress resilience properties. Psychopharmacology. PMID 31119329 DOI: 10.1007/S00213-019-05253-9 |
0.704 |
|
| 2019 |
Giannakis N, Sansbury BE, Patsalos A, Hays TT, Riley CO, Han X, Spite M, Nagy L. Dynamic changes to lipid mediators support transitions among macrophage subtypes during muscle regeneration. Nature Immunology. PMID 30936495 DOI: 10.1038/S41590-019-0356-7 |
0.308 |
|
| 2019 |
Horvath A, Daniel B, Szeles L, Cuaranta-Monroy I, Czimmerer Z, Ozgyin L, Steiner L, Kiss M, Simandi Z, Poliska S, Giannakis N, Raineri E, Gut IG, Nagy B, Nagy L. Labelled regulatory elements are pervasive features of the macrophage genome and are dynamically utilized by classical and alternative polarization signals. Nucleic Acids Research. PMID 30799488 DOI: 10.1093/Nar/Gkz118 |
0.393 |
|
| 2018 |
Daniel B, Nagy G, Czimmerer Z, Horvath A, Hammers DW, Cuaranta-Monroy I, Poliska S, Tzerpos P, Kolostyak Z, Hays TT, Patsalos A, Houtman R, Sauer S, Francois-Deleuze J, Rastinejad F, ... ... Nagy L, et al. The Nuclear Receptor PPARγ Controls Progressive Macrophage Polarization as a Ligand-Insensitive Epigenomic Ratchet of Transcriptional Memory. Immunity. 49: 615-626.e6. PMID 30332629 DOI: 10.1016/J.Immuni.2018.09.005 |
0.4 |
|
| 2018 |
Moreira TG, Horta LS, Gomes-Santos AC, Oliveira RP, Queiroz NMGP, Mangani D, Daniel B, Vieira AT, Liu S, Rodrigues AM, Gomes DA, Gabriely G, Ferreira E, Weiner HL, Rezende RM, ... Nagy L, et al. CLA-supplemented diet accelerates experimental colorectal cancer by inducing TGF-β-producing macrophages and T cells. Mucosal Immunology. PMID 30279515 DOI: 10.1038/S41385-018-0090-8 |
0.325 |
|
| 2018 |
Simandi Z, Pajer K, Karolyi K, Sieler T, Jiang LL, Kolostyak Z, Sari Z, Fekecs Z, Pap A, Patsalos A, Contreras GA, Reho B, Papp Z, Guo X, Horvath A, ... ... Nagy L, et al. Arginine methyltransferase PRMT8 provides cellular stress tolerance in aging motoneurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 30054395 DOI: 10.1523/Jneurosci.3389-17.2018 |
0.3 |
|
| 2018 |
Beceiro S, Pap A, Czimmerer Z, Sallam T, Guillén JA, Gallardo G, Hong C, A-Gonzalez N, Tabraue C, Diaz M, Lopez F, Matalonga J, Valledor AF, Dominguez P, Ardavin C, ... ... Nagy L, et al. LXR nuclear receptors are transcriptional regulators of dendritic cell chemotaxis. Molecular and Cellular Biology. PMID 29507185 DOI: 10.1128/Mcb.00534-17 |
0.402 |
|
| 2018 |
Daniel B, Nagy G, Horvath A, Czimmerer Z, Cuaranta-Monroy I, Poliska S, Hays TT, Sauer S, Francois-Deleuze J, Nagy L. The IL-4/STAT6/PPARγ signaling axis is driving the expansion of the RXR heterodimer cistrome, providing complex ligand responsiveness in macrophages. Nucleic Acids Research. PMID 29506156 DOI: 10.1093/Nar/Gky157 |
0.443 |
|
| 2018 |
Sallam T, Jones M, Thomas BJ, Wu X, Gilliland T, Qian K, Eskin A, Casero D, Zhang Z, Sandhu J, Salisbury D, Rajbhandari P, Civelek M, Hong C, Ito A, ... ... Nagy L, et al. Transcriptional regulation of macrophage cholesterol efflux and atherogenesis by a long noncoding RNA. Nature Medicine. PMID 29431742 DOI: 10.1038/Nm.4479 |
0.443 |
|
| 2018 |
Czimmerer Z, Daniel B, Horvath A, Rückerl D, Nagy G, Kiss M, Peloquin M, Budai MM, Cuaranta-Monroy I, Simandi Z, Steiner L, Nagy B, Poliska S, Banko C, Bacso Z, ... ... Nagy L, et al. The Transcription Factor STAT6 Mediates Direct Repression of Inflammatory Enhancers and Limits Activation of Alternatively Polarized Macrophages. Immunity. 48: 75-90.e6. PMID 29343442 DOI: 10.1016/J.Immuni.2017.12.010 |
0.345 |
|
| 2017 |
Czimmerer Z, Horvath A, Daniel B, Nagy G, Cuaranta-Monroy I, Kiss M, Kolostyak Z, Poliska S, Steiner L, Giannakis N, Varga T, Nagy L. Dynamic transcriptional control of macrophage miRNA signature via inflammation responsive enhancers revealed using a combination of next generation sequencing-based approaches. Biochimica Et Biophysica Acta. PMID 29133016 DOI: 10.1016/J.Bbagrm.2017.11.003 |
0.306 |
|
| 2017 |
Kiss M, Czimmerer Z, Nagy G, Bieniasz-Krzywiec P, Ehling M, Pap A, Poliska S, Boto P, Tzerpos P, Horvath A, Kolostyak Z, Daniel B, Szatmari I, Mazzone M, Nagy L. Retinoid X receptor suppresses a metastasis-promoting transcriptional program in myeloid cells via a ligand-insensitive mechanism. Proceedings of the National Academy of Sciences of the United States of America. PMID 28923935 DOI: 10.1073/Pnas.1700785114 |
0.449 |
|
| 2017 |
Simandi Z, Horvath A, Cuaranta-Monroy I, Sauer S, Deleuze JF, Nagy L. RXR heterodimers orchestrate transcriptional control of neurogenesis and cell fate specification. Molecular and Cellular Endocrinology. PMID 28778663 DOI: 10.1016/J.Mce.2017.07.033 |
0.398 |
|
| 2017 |
Czimmerer Z, Nagy ZS, Nagy G, Horvath A, Silye-Cseh T, Kriston A, Jonas D, Sauer S, Steiner L, Daniel B, Deleuze JF, Nagy L. Extensive and functional overlap of the STAT6 and RXR cistromes in the active enhancer repertoire of human CD14+ monocyte derived differentiating macrophages. Molecular and Cellular Endocrinology. PMID 28774779 DOI: 10.1016/J.Mce.2017.07.034 |
0.388 |
|
| 2017 |
Bermudez B, Dahl TB, Medina I, Groeneweg M, Holm S, Montserrat-de la Paz S, Rousch M, Otten JJ, Herias V, Varela LM, Ranheim T, Yndestad A, Ortega-Gomez A, Abia R, Nagy L, et al. Leukocyte Overexpression of Intracellular NAMPT Attenuates Atherosclerosis by Regulating PPARγ-Dependent Monocyte Differentiation and Function. Arteriosclerosis, Thrombosis, and Vascular Biology. PMID 28408371 DOI: 10.1161/Atvbaha.116.308187 |
0.325 |
|
| 2016 |
Varga T, Mounier R, Patsalos A, Gogolák P, Peloquin M, Horvath A, Pap A, Daniel B, Nagy G, Pintye E, Poliska S, Cuvellier S, Ben Larbi S, Sansbury BE, Spite M, ... ... Nagy L, et al. Macrophage PPARγ, a Lipid Activated Transcription Factor Controls the Growth Factor GDF3 and Skeletal Muscle Regeneration. Immunity. PMID 27836432 DOI: 10.1016/J.Immuni.2016.10.016 |
0.334 |
|
| 2016 |
Simandi Z, Horvath A, Wright LC, Cuaranta-Monroy I, De Luca I, Karolyi K, Sauer S, Deleuze JF, Gudas LJ, Cowley SM, Nagy L. OCT4 Acts as an Integrator of Pluripotency and Signal-Induced Differentiation. Molecular Cell. PMID 27499297 DOI: 10.1016/J.Molcel.2016.06.039 |
0.378 |
|
| 2016 |
Pap A, Cuaranta-Monroy I, Peloquin M, Nagy L. Is the Mouse a Good Model of Human PPARγ-Related Metabolic Diseases? International Journal of Molecular Sciences. 17. PMID 27483259 DOI: 10.3390/Ijms17081236 |
0.317 |
|
| 2016 |
Simandi Z, Horvath A, Nagy P, Nagy L. Prediction and Validation of Gene Regulatory Elements Activated During Retinoic Acid Induced Embryonic Stem Cell Differentiation. Journal of Visualized Experiments : Jove. PMID 27403939 DOI: 10.3791/53978 |
0.371 |
|
| 2016 |
Czimmerer Z, Varga T, Kiss M, Vázquez CO, Doan-Xuan QM, Rückerl D, Tattikota SG, Yan X, Nagy ZS, Daniel B, Poliska S, Horvath A, Nagy G, Varallyay E, Poy MN, ... ... Nagy L, et al. The IL-4/STAT6 signaling axis establishes a conserved microRNA signature in human and mouse macrophages regulating cell survival via miR-342-3p. Genome Medicine. 8: 63. PMID 27245778 DOI: 10.1186/S13073-016-0315-Y |
0.322 |
|
| 2016 |
Varga T, Mounier R, Horvath A, Cuvellier S, Dumont F, Poliska S, Ardjoune H, Juban G, Nagy L, Chazaud B. Highly Dynamic Transcriptional Signature of Distinct Macrophage Subsets during Sterile Inflammation, Resolution, and Tissue Repair. Journal of Immunology (Baltimore, Md. : 1950). PMID 27183604 DOI: 10.4049/Jimmunol.1502490 |
0.36 |
|
| 2016 |
Dozsa A, Mihaly J, Dezso B, Csizmadia E, Keresztessy T, Marko L, Rühl R, Remenyik E, Nagy L. Decreased peroxisome proliferator-activated receptor γ level and signalling in sebaceous glands of patients with acne vulgaris. Clinical and Experimental Dermatology. 41: 547-551. PMID 26800853 DOI: 10.1111/Ced.12794 |
0.397 |
|
| 2015 |
Cuaranta-Monroy I, Kiss M, Simandi Z, Nagy L. Genomewide effects of peroxisome proliferator-activated receptor gamma in macrophages and dendritic cells--revealing complexity through systems biology. European Journal of Clinical Investigation. 45: 964-75. PMID 26251129 DOI: 10.1111/Eci.12491 |
0.333 |
|
| 2015 |
Rühl R, Krzy?osiak A, Niewiadomska-Cimicka A, Rochel N, Szeles L, Vaz B, Wietrzych-Schindler M, Álvarez S, Szklenar M, Nagy L, de Lera AR, Kr??el W. 9-cis-13,14-Dihydroretinoic Acid Is an Endogenous Retinoid Acting as RXR Ligand in Mice. Plos Genetics. 11: e1005213. PMID 26030625 DOI: 10.1371/Journal.Pgen.1005213 |
0.391 |
|
| 2015 |
Simandi Z, Czipa E, Horvath A, Koszeghy A, Bordas C, Póliska S, Juhász I, Imre L, Szabó G, Dezso B, Barta E, Sauer S, Karolyi K, Kovacs I, Hutóczki G, ... ... Nagy L, et al. PRMT1 and PRMT8 regulate retinoic acid-dependent neuronal differentiation with implications to neuropathology. Stem Cells (Dayton, Ohio). 33: 726-41. PMID 25388207 DOI: 10.1002/Stem.1894 |
0.377 |
|
| 2014 |
Kotlinowski J, Grochot-Przeczek A, Taha H, Kozakowska M, Pilecki B, Skrzypek K, Bartelik A, Derlacz R, Horrevoets AJ, Pap A, Nagy L, Dulak J, Jozkowicz A. PPARγ activation but not PPARγ haplodeficiency affects proangiogenic potential of endothelial cells and bone marrow-derived progenitors. Cardiovascular Diabetology. 13: 150. PMID 25361524 DOI: 10.1186/S12933-014-0150-7 |
0.307 |
|
| 2014 |
Daniel B, Balint BL, Nagy ZS, Nagy L. Mapping the genomic binding sites of the activated retinoid X receptor in murine bone marrow-derived macrophages using chromatin immunoprecipitation sequencing. Methods in Molecular Biology (Clifton, N.J.). 1204: 15-24. PMID 25182757 DOI: 10.1007/978-1-4939-1346-6_2 |
0.376 |
|
| 2014 |
Daniel B, Nagy G, Hah N, Horvath A, Czimmerer Z, Poliska S, Gyuris T, Keirsse J, Gysemans C, Van Ginderachter JA, Balint BL, Evans RM, Barta E, Nagy L. The active enhancer network operated by liganded RXR supports angiogenic activity in macrophages. Genes & Development. 28: 1562-77. PMID 25030696 DOI: 10.1101/Gad.242685.114 |
0.376 |
|
| 2014 |
Daniel B, Nagy G, Nagy L. The intriguing complexities of mammalian gene regulation: how to link enhancers to regulated genes. Are we there yet? Febs Letters. 588: 2379-91. PMID 24945732 DOI: 10.1016/J.Febslet.2014.05.041 |
0.349 |
|
| 2014 |
Cuaranta-Monroy I, Simandi Z, Kolostyak Z, Doan-Xuan QM, Poliska S, Horvath A, Nagy G, Bacso Z, Nagy L. Highly efficient differentiation of embryonic stem cells into adipocytes by ascorbic acid. Stem Cell Research. 13: 88-97. PMID 24858493 DOI: 10.1016/J.Scr.2014.04.015 |
0.306 |
|
| 2014 |
Brazda P, Krieger J, Daniel B, Jonas D, Szekeres T, Langowski J, Tóth K, Nagy L, Vámosi G. Ligand binding shifts highly mobile retinoid X receptor to the chromatin-bound state in a coactivator-dependent manner, as revealed by single-cell imaging. Molecular and Cellular Biology. 34: 1234-45. PMID 24449763 DOI: 10.1128/Mcb.01097-13 |
0.752 |
|
| 2014 |
Dozsa A, Dezso B, Toth BI, Bacsi A, Poliska S, Camera E, Picardo M, Zouboulis CC, Bíró T, Schmitz G, Liebisch G, Rühl R, Remenyik E, Nagy L. PPARγ-mediated and arachidonic acid-dependent signaling is involved in differentiation and lipid production of human sebocytes. The Journal of Investigative Dermatology. 134: 910-20. PMID 24129064 DOI: 10.1038/Jid.2013.413 |
0.384 |
|
| 2013 |
Brignull LM, Czimmerer Z, Saidi H, Daniel B, Villela I, Bartlett NW, Johnston SL, Meira LB, Nagy L, Nohturfft A. Reprogramming of lysosomal gene expression by interleukin-4 and Stat6. Bmc Genomics. 14: 853. PMID 24314139 DOI: 10.1186/1471-2164-14-853 |
0.337 |
|
| 2013 |
Cuaranta-Monroy I, Nagy L. PPARγ needs a helping hand to make fat. Cell Death and Differentiation. 20: 1599-600. PMID 24212929 DOI: 10.1038/Cdd.2013.151 |
0.384 |
|
| 2013 |
Nagy L. Nuclear hormone receptors are powerful regulators of stem cell maintenance, differentiation, metabolism and function. Seminars in Cell & Developmental Biology. 24: 669. PMID 24184383 DOI: 10.1016/J.Semcdb.2013.10.006 |
0.344 |
|
| 2013 |
Simandi Z, Cuaranta-Monroy I, Nagy L. Nuclear receptors as regulators of stem cell and cancer stem cell metabolism. Seminars in Cell & Developmental Biology. 24: 716-23. PMID 24184382 DOI: 10.1016/J.Semcdb.2013.10.002 |
0.331 |
|
| 2013 |
Varga T, Mounier R, Gogolak P, Poliska S, Chazaud B, Nagy L. Tissue LyC6- macrophages are generated in the absence of circulating LyC6- monocytes and Nur77 in a model of muscle regeneration. Journal of Immunology (Baltimore, Md. : 1950). 191: 5695-701. PMID 24133167 DOI: 10.4049/Jimmunol.1301445 |
0.332 |
|
| 2013 |
Nagy G, Dániel B, Jónás D, Nagy L, Barta E. A novel method to predict regulatory regions based on histone mark landscapes in macrophages. Immunobiology. 218: 1416-27. PMID 23973299 DOI: 10.1016/J.Imbio.2013.07.006 |
0.363 |
|
| 2013 |
Kiss M, Czimmerer Z, Nagy L. The role of lipid-activated nuclear receptors in shaping macrophage and dendritic cell function: From physiology to pathology. The Journal of Allergy and Clinical Immunology. 132: 264-86. PMID 23905916 DOI: 10.1016/J.Jaci.2013.05.044 |
0.437 |
|
| 2013 |
Nagy ZS, Czimmerer Z, Szanto A, Nagy L. Pro-inflammatory cytokines negatively regulate PPARγ mediated gene expression in both human and murine macrophages via multiple mechanisms. Immunobiology. 218: 1336-44. PMID 23870825 DOI: 10.1016/J.Imbio.2013.06.011 |
0.412 |
|
| 2013 |
Szénási T, Kénesi E, Nagy A, Molnár A, Bálint BL, Zvara Ã, Csabai Z, Deák F, Boros Oláh B, Mátés L, Nagy L, Puskás LG, Kiss I. Hmgb1 can facilitate activation of the matrilin-1 gene promoter by Sox9 and L-Sox5/Sox6 in early steps of chondrogenesis. Biochimica Et Biophysica Acta. 1829: 1075-91. PMID 23860260 DOI: 10.1016/J.Bbagrm.2013.07.004 |
0.376 |
|
| 2013 |
Gyöngyösi A, Szatmari I, Pap A, Dezso B, Pos Z, Széles L, Varga T, Nagy L. RDH10, RALDH2, and CRABP2 are required components of PPARγ-directed ATRA synthesis and signaling in human dendritic cells. Journal of Lipid Research. 54: 2458-74. PMID 23833249 DOI: 10.1194/Jlr.M038984 |
0.396 |
|
| 2013 |
Nagy ZS, Ross JA, Rodriguez G, Balint BL, Szeles L, Nagy L, Kirken RA. Genome wide mapping reveals PDE4B as an IL-2 induced STAT5 target gene in activated human PBMCs and lymphoid cancer cells. Plos One. 8: e57326. PMID 23451206 DOI: 10.1371/Journal.Pone.0057326 |
0.35 |
|
| 2013 |
Nagy ZS, Czimmerer Z, Nagy L. Nuclear receptor mediated mechanisms of macrophage cholesterol metabolism. Molecular and Cellular Endocrinology. 368: 85-98. PMID 22546548 DOI: 10.1016/J.Mce.2012.04.003 |
0.411 |
|
| 2012 |
Czimmerer Z, Varga T, Poliska S, Nemet I, Szanto A, Nagy L. Identification of novel markers of alternative activation and potential endogenous PPARγ ligand production mechanisms in human IL-4 stimulated differentiating macrophages. Immunobiology. 217: 1301-14. PMID 22954708 DOI: 10.1016/J.Imbio.2012.08.270 |
0.385 |
|
| 2012 |
Nagy L. Would eating carrots protect your liver? A new role involving NKT cells for retinoic acid in hepatitis. European Journal of Immunology. 42: 1677-80. PMID 22806070 DOI: 10.1002/Eji.201242705 |
0.344 |
|
| 2012 |
Nagy L, Szanto A, Szatmari I, Széles L. Nuclear hormone receptors enable macrophages and dendritic cells to sense their lipid environment and shape their immune response. Physiological Reviews. 92: 739-89. PMID 22535896 DOI: 10.1152/Physrev.00004.2011 |
0.354 |
|
| 2012 |
Mesko B, Poliska S, Szamosi S, Szekanecz Z, Podani J, Varadi C, Guttman A, Nagy L. Peripheral blood gene expression and IgG glycosylation profiles as markers of tocilizumab treatment in rheumatoid arthritis. The Journal of Rheumatology. 39: 916-28. PMID 22467923 DOI: 10.3899/Jrheum.110961 |
0.315 |
|
| 2012 |
Tsakiris I, Torocsik D, Gyongyosi A, Dozsa A, Szatmari I, Szanto A, Soos G, Nemes Z, Igali L, Marton I, Takats Z, Nagy L, Dezso B. Carboxypeptidase-M is regulated by lipids and CSFs in macrophages and dendritic cells and expressed selectively in tissue granulomas and foam cells. Laboratory Investigation; a Journal of Technical Methods and Pathology. 92: 345-61. PMID 22157720 DOI: 10.1038/Labinvest.2011.168 |
0.379 |
|
| 2012 |
Nagy Z, Czimmerer Z, Szanto A, Daniel B, Schwabe J, Nagy L. P057 Cytokine mediated regulation of PPARg activity in human macrophages Cytokine. 59: 536. DOI: 10.1016/J.Cyto.2012.06.141 |
0.423 |
|
| 2011 |
Brazda P, Szekeres T, Bravics B, Tóth K, Vámosi G, Nagy L. Live-cell fluorescence correlation spectroscopy dissects the role of coregulator exchange and chromatin binding in retinoic acid receptor mobility. Journal of Cell Science. 124: 3631-42. PMID 22045737 DOI: 10.1242/Jcs.086082 |
0.755 |
|
| 2011 |
Nakken B, Varga T, Szatmari I, Szeles L, Gyongyosi A, Illarionov PA, Dezso B, Gogolak P, Rajnavolgyi E, Nagy L. Peroxisome proliferator-activated receptor γ-regulated cathepsin D is required for lipid antigen presentation by dendritic cells. Journal of Immunology (Baltimore, Md. : 1950). 187: 240-7. PMID 21632707 DOI: 10.4049/Jimmunol.1002421 |
0.369 |
|
| 2011 |
Mesko B, Poliska S, Nagy L. Gene expression profiles in peripheral blood for the diagnosis of autoimmune diseases. Trends in Molecular Medicine. 17: 223-33. PMID 21388884 DOI: 10.1016/J.Molmed.2010.12.004 |
0.306 |
|
| 2011 |
Varga T, Czimmerer Z, Nagy L. PPARs are a unique set of fatty acid regulated transcription factors controlling both lipid metabolism and inflammation. Biochimica Et Biophysica Acta. 1812: 1007-22. PMID 21382489 DOI: 10.1016/J.Bbadis.2011.02.014 |
0.433 |
|
| 2011 |
Meskó B, Poliska S, Szamosi S, Szekanecz Z, Podani J, Nagy L. Combination of peripheral blood gene expression profiles and clinical parameters predicts response to tocilizumab treatment in rheumatoid arthritis Annals of the Rheumatic Diseases. 70. DOI: 10.1136/Ard.2010.148965.1 |
0.318 |
|
| 2010 |
Szanto A, Balint BL, Nagy ZS, Barta E, Dezso B, Pap A, Szeles L, Poliska S, Oros M, Evans RM, Barak Y, Schwabe J, Nagy L. STAT6 transcription factor is a facilitator of the nuclear receptor PPARγ-regulated gene expression in macrophages and dendritic cells. Immunity. 33: 699-712. PMID 21093321 DOI: 10.1016/J.Immuni.2010.11.009 |
0.452 |
|
| 2010 |
Széles L, Póliska S, Nagy G, Szatmari I, Szanto A, Pap A, Lindstedt M, Santegoets SJ, Rühl R, Dezsö B, Nagy L. Research resource: transcriptome profiling of genes regulated by RXR and its permissive and nonpermissive partners in differentiating monocyte-derived dendritic cells. Molecular Endocrinology (Baltimore, Md.). 24: 2218-31. PMID 20861222 DOI: 10.1210/Me.2010-0215 |
0.435 |
|
| 2010 |
Töröcsik D, Szeles L, Paragh G, Rakosy Z, Bardos H, Nagy L, Balazs M, Inbal A, Adány R. Factor XIII-A is involved in the regulation of gene expression in alternatively activated human macrophages. Thrombosis and Haemostasis. 104: 709-17. PMID 20664907 DOI: 10.1160/Th09-11-0805 |
0.355 |
|
| 2010 |
Simandi Z, Balint BL, Poliska S, Ruhl R, Nagy L. Activation of retinoic acid receptor signaling coordinates lineage commitment of spontaneously differentiating mouse embryonic stem cells in embryoid bodies. Febs Letters. 584: 3123-30. PMID 20621839 DOI: 10.1016/J.Febslet.2010.05.052 |
0.314 |
|
| 2010 |
Mesko B, Poliska S, Szegedi A, Szekanecz Z, Palatka K, Papp M, Nagy L. Peripheral blood gene expression patterns discriminate among chronic inflammatory diseases and healthy controls and identify novel targets. Bmc Medical Genomics. 3: 15. PMID 20444268 DOI: 10.1186/1755-8794-3-15 |
0.3 |
|
| 2010 |
Töröcsik D, Baráth M, Benko S, Széles L, Dezso B, Póliska S, Hegyi Z, Homolya L, Szatmári I, Lányi A, Nagy L. Activation of liver X receptor sensitizes human dendritic cells to inflammatory stimuli. Journal of Immunology (Baltimore, Md. : 1950). 184: 5456-65. PMID 20410489 DOI: 10.4049/Jimmunol.0902399 |
0.391 |
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| 2009 |
Almeida PE, Silva AR, Maya-Monteiro CM, Töröcsik D, D'Avila H, Dezsö B, Magalhães KG, Castro-Faria-Neto HC, Nagy L, Bozza PT. Mycobacterium bovis bacillus Calmette-Guérin infection induces TLR2-dependent peroxisome proliferator-activated receptor gamma expression and activation: functions in inflammation, lipid metabolism, and pathogenesis. Journal of Immunology (Baltimore, Md. : 1950). 183: 1337-45. PMID 19561094 DOI: 10.4049/Jimmunol.0900365 |
0.363 |
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| 2009 |
Töröcsik D, Szanto A, Nagy L. Oxysterol signaling links cholesterol metabolism and inflammation via the liver X receptor in macrophages. Molecular Aspects of Medicine. 30: 134-52. PMID 19248804 DOI: 10.1016/J.Mam.2009.02.002 |
0.451 |
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| 2009 |
Széles L, Keresztes G, Töröcsik D, Balajthy Z, Krenács L, Póliska S, Steinmeyer A, Zuegel U, Pruenster M, Rot A, Nagy L. 1,25-dihydroxyvitamin D3 is an autonomous regulator of the transcriptional changes leading to a tolerogenic dendritic cell phenotype. Journal of Immunology (Baltimore, Md. : 1950). 182: 2074-83. PMID 19201860 DOI: 10.4049/Jimmunol.0803345 |
0.401 |
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| 2009 |
Tóth BI, Géczy T, Griger Z, Dózsa A, Seltmann H, Kovács L, Nagy L, Zouboulis CC, Paus R, Bíró T. Transient Receptor Potential Vanilloid-1 Signaling as a Regulator of Human Sebocyte Biology Journal of Investigative Dermatology. 129: 329-339. PMID 18769453 DOI: 10.1038/Jid.2008.258 |
0.375 |
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| 2008 |
Itoh T, Fairall L, Amin K, Inaba Y, Szanto A, Balint BL, Nagy L, Yamamoto K, Schwabe JW. Structural basis for the activation of PPARgamma by oxidized fatty acids. Nature Structural & Molecular Biology. 15: 924-31. PMID 19172745 DOI: 10.1038/Nsmb.1474 |
0.374 |
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| 2008 |
Gyöngyösi A, Nagy L. Potential Therapeutic Use of PPARgamma-Programed Human Monocyte-Derived Dendritic Cells in Cancer Vaccination Therapy. Ppar Research. 2008: 473804. PMID 19009040 DOI: 10.1155/2008/473804 |
0.318 |
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| 2008 |
Szanto A, Nagy L. The many faces of PPARgamma: anti-inflammatory by any means? Immunobiology. 213: 789-803. PMID 18926294 DOI: 10.1016/J.Imbio.2008.07.015 |
0.417 |
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| 2008 |
Varga T, Nagy L. Nuclear receptors, transcription factors linking lipid metabolism and immunity: the case of peroxisome proliferator-activated receptor gamma. European Journal of Clinical Investigation. 38: 695-707. PMID 18837794 DOI: 10.1111/J.1365-2362.2008.02022.X |
0.464 |
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| 2008 |
Szatmari I, Nagy L. Nuclear receptor signalling in dendritic cells connects lipids, the genome and immune function. The Embo Journal. 27: 2353-62. PMID 18716631 DOI: 10.1038/Emboj.2008.160 |
0.394 |
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| 2008 |
Seres L, Cserepes J, Elkind NB, Törocsik D, Nagy L, Sarkadi B, Homolya L. Functional ABCG1 expression induces apoptosis in macrophages and other cell types. Biochimica Et Biophysica Acta. 1778: 2378-87. PMID 18619413 DOI: 10.1016/J.Bbamem.2008.06.010 |
0.373 |
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| 2008 |
Dobrosi N, Tóth BI, Nagy G, Dózsa A, Géczy T, Nagy L, Zouboulis CC, Paus R, Kovács L, Bíró T. Endocannabinoids enhance lipid synthesis and apoptosis of human sebocytes via cannabinoid receptor-2-mediated signaling The Faseb Journal. 22: 3685-3695. PMID 18596221 DOI: 10.1096/Fj.07-104877 |
0.393 |
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| 2007 |
Szatmari I, Töröcsik D, Agostini M, Nagy T, Gurnell M, Barta E, Chatterjee K, Nagy L. PPARgamma regulates the function of human dendritic cells primarily by altering lipid metabolism. Blood. 110: 3271-80. PMID 17664351 DOI: 10.1182/Blood-2007-06-096222 |
0.43 |
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| 2007 |
Széles L, Töröcsik D, Nagy L. PPARgamma in immunity and inflammation: cell types and diseases. Biochimica Et Biophysica Acta. 1771: 1014-30. PMID 17418635 DOI: 10.1016/J.Bbalip.2007.02.005 |
0.411 |
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| 2007 |
Szatmari I, Rajnavolgyi E, Nagy L. PPARgamma, a lipid-activated transcription factor as a regulator of dendritic cell function. Annals of the New York Academy of Sciences. 1088: 207-18. PMID 17192567 DOI: 10.1196/Annals.1366.013 |
0.384 |
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| 2006 |
Agostini M, Schoenmakers E, Mitchell C, Szatmari I, Savage D, Smith A, Rajanayagam O, Semple R, Luan J, Bath L, Zalin A, Labib M, Kumar S, Simpson H, Blom D, ... ... Nagy L, et al. Non-DNA binding, dominant-negative, human PPARgamma mutations cause lipodystrophic insulin resistance. Cell Metabolism. 4: 303-11. PMID 17011503 DOI: 10.1016/J.Cmet.2006.09.003 |
0.377 |
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| 2006 |
Szatmari I, Pap A, Rühl R, Ma JX, Illarionov PA, Besra GS, Rajnavolgyi E, Dezso B, Nagy L. PPARgamma controls CD1d expression by turning on retinoic acid synthesis in developing human dendritic cells. The Journal of Experimental Medicine. 203: 2351-62. PMID 16982809 DOI: 10.1084/Jem.20060141 |
0.408 |
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| 2006 |
Gogolak P, Rethi B, Szatmari I, Lanyi A, Dezso B, Nagy L, Rajnavolgyi E. Differentiation of CD1a- and CD1a+ monocyte-derived dendritic cells is biased by lipid environment and PPARgamma. Blood. 109: 643-52. PMID 16968896 DOI: 10.1182/Blood-2006-04-016840 |
0.407 |
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| 2006 |
Szatmari I, Vámosi G, Brazda P, Balint BL, Benko S, Széles L, Jeney V, Ozvegy-Laczka C, Szántó A, Barta E, Balla J, Sarkadi B, Nagy L. Peroxisome proliferator-activated receptor gamma-regulated ABCG2 expression confers cytoprotection to human dendritic cells. The Journal of Biological Chemistry. 281: 23812-23. PMID 16785230 DOI: 10.1074/Jbc.M604890200 |
0.757 |
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| 2006 |
Nagy L, Schüle R, Gronemeyer H. Twenty years of nuclear receptors: Conference on Nuclear Receptors: from Chromatin to Disease. Embo Reports. 7: 579-84. PMID 16729019 DOI: 10.1038/Sj.Embor.7400711 |
0.418 |
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| 2006 |
Balint BL, Nagy L. Selective modulators of PPAR activity as new therapeutic tools in metabolic diseases. Endocrine, Metabolic & Immune Disorders Drug Targets. 6: 33-43. PMID 16611163 DOI: 10.2174/187153006776056620 |
0.418 |
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| 2005 |
Réthi B, Gogolák P, Szatmari I, Veres A, Erdôs E, Nagy L, Rajnavölgyi E, Terhorst C, Lányi A. SLAM/SLAM interactions inhibit CD40-induced production of inflammatory cytokines in monocyte-derived dendritic cells. Blood. 107: 2821-9. PMID 16317102 DOI: 10.1182/Blood-2005-06-2265 |
0.321 |
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| 2005 |
Nagy L, Szanto A. Roles for lipid-activated transcription factors in atherosclerosis. Molecular Nutrition & Food Research. 49: 1072-4. PMID 16208627 DOI: 10.1002/Mnfr.200500097 |
0.436 |
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| 2005 |
Balint BL, Gabor P, Nagy L. Genome-wide localization of histone 4 arginine 3 methylation in a differentiation primed myeloid leukemia cell line. Immunobiology. 210: 141-52. PMID 16164021 DOI: 10.1016/J.Imbio.2005.05.009 |
0.314 |
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| 2005 |
Balint BL, Szanto A, Madi A, Bauer UM, Gabor P, Benko S, Puskás LG, Davies PJ, Nagy L. Arginine methylation provides epigenetic transcription memory for retinoid-induced differentiation in myeloid cells. Molecular and Cellular Biology. 25: 5648-63. PMID 15964820 DOI: 10.1128/Mcb.25.13.5648-5663.2005 |
0.368 |
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| 2005 |
Szanto A, Nagy L. Retinoids potentiate peroxisome proliferator-activated receptor gamma action in differentiation, gene expression, and lipid metabolic processes in developing myeloid cells. Molecular Pharmacology. 67: 1935-43. PMID 15741503 DOI: 10.1124/Mol.104.006445 |
0.46 |
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| 2004 |
Szanto A, Narkar V, Shen Q, Uray IP, Davies PJ, Nagy L. Retinoid X receptors: X-ploring their (patho)physiological functions. Cell Death and Differentiation. 11: S126-43. PMID 15608692 DOI: 10.1038/Sj.Cdd.4401533 |
0.411 |
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| 2004 |
Szatmari I, Gogolak P, Im JS, Dezso B, Rajnavolgyi E, Nagy L. Activation of PPARgamma specifies a dendritic cell subtype capable of enhanced induction of iNKT cell expansion. Immunity. 21: 95-106. PMID 15345223 DOI: 10.1016/J.Immuni.2004.06.003 |
0.424 |
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| 2004 |
Szanto A, Benko S, Szatmari I, Balint BL, Furtos I, Rühl R, Molnar S, Csiba L, Garuti R, Calandra S, Larsson H, Diczfalusy U, Nagy L. Transcriptional regulation of human CYP27 integrates retinoid, peroxisome proliferator-activated receptor, and liver X receptor signaling in macrophages. Molecular and Cellular Biology. 24: 8154-66. PMID 15340076 DOI: 10.1128/Mcb.24.18.8154-8166.2004 |
0.443 |
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| 2004 |
Nagy L, Schwabe JW. Mechanism of the nuclear receptor molecular switch. Trends in Biochemical Sciences. 29: 317-24. PMID 15276186 DOI: 10.1016/J.Tibs.2004.04.006 |
0.428 |
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| 2003 |
Benko S, Love JD, Beládi M, Schwabe JWR, Nagy L. Molecular Determinants of the Balance between Co-repressor and Co-activator Recruitment to the Retinoic Acid Receptor Journal of Biological Chemistry. 278: 43797-43806. PMID 12917445 DOI: 10.1074/Jbc.M306199200 |
0.401 |
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| 2002 |
Love JD, Gooch JT, Benko S, Li C, Nagy L, Chatterjee VK, Evans RM, Schwabe JW. The structural basis for the specificity of retinoid-X receptor-selective agonists: new insights into the role of helix H12. The Journal of Biological Chemistry. 277: 11385-91. PMID 11782480 DOI: 10.1074/Jbc.M110869200 |
0.379 |
|
| 2001 |
Singh Ahuja H, Liu S, Crombie DL, Boehm M, Leibowitz MD, Heyman RA, Depre C, Nagy L, Tontonoz P, Davies PJ. Differential effects of rexinoids and thiazolidinediones on metabolic gene expression in diabetic rodents. Molecular Pharmacology. 59: 765-73. PMID 11259621 DOI: 10.1124/Mol.59.4.765 |
0.325 |
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| 2001 |
Chawla A, Boisvert WA, Lee CH, Laffitte BA, Barak Y, Joseph SB, Liao D, Nagy L, Edwards PA, Curtiss LK, Evans RM, Tontonoz P. A PPAR gamma-LXR-ABCA1 pathway in macrophages is involved in cholesterol efflux and atherogenesis. Molecular Cell. 7: 161-71. PMID 11172721 DOI: 10.1016/S1097-2765(01)00164-2 |
0.344 |
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| 2001 |
Chawla A, Barak Y, Nagy L, Liao D, Tontonoz P, Evans RM. PPAR-gamma dependent and independent effects on macrophage-gene expression in lipid metabolism and inflammation. Nature Medicine. 7: 48-52. PMID 11135615 DOI: 10.1038/83336 |
0.409 |
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| 2000 |
Szegezdi E, Szondy Z, Nagy L, Nemes Z, Friis RR, Davies PJ, Fésüs L. Apoptosis-linked in vivo regulation of the tissue transglutaminase gene promoter. Cell Death and Differentiation. 7: 1225-33. PMID 11175260 DOI: 10.1038/Sj.Cdd.4400751 |
0.369 |
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| 2000 |
Lee H, Shi W, Tontonoz P, Wang S, Subbanagounder G, Hedrick CC, Hama S, Borromeo C, Evans RM, Berliner JA, Nagy L. Role for peroxisome proliferator-activated receptor alpha in oxidized phospholipid-induced synthesis of monocyte chemotactic protein-1 and interleukin-8 by endothelial cells. Circulation Research. 87: 516-21. PMID 10988245 DOI: 10.1161/01.Res.87.6.516 |
0.386 |
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| 2000 |
Love JD, Gooch JT, Nagy L, Chatterjee VKK, Schwabe JWR. Transcriptional repression by nuclear receptors: mechanisms and role in disease Biochemical Society Transactions. 28: 390-396. DOI: 10.1042/Bst0280390 |
0.415 |
|
| 1999 |
Tontonoz P, Nagy L. Regulation of macrophage gene expression by peroxisome-proliferator-activated receptor y: implications for cardiovascular disease Current Opinion in Lipidology. 10: 485-490. PMID 10680041 DOI: 10.1097/00041433-199912000-00002 |
0.439 |
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| 1999 |
Nagy L, Kao HY, Love JD, Li C, Banayo E, Gooch JT, Krishna V, Chatterjee K, Evans RM, Schwabe JW. Mechanism of corepressor binding and release from nuclear hormone receptors. Genes & Development. 13: 3209-16. PMID 10617570 DOI: 10.1101/Gad.13.24.3209 |
0.404 |
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| 1999 |
Dupé V, Ghyselinck NB, Thomazy V, Nagy L, Davies PJ, Chambon P, Mark M. Essential roles of retinoic acid signaling in interdigital apoptosis and control of BMP-7 expression in mouse autopods. Developmental Biology. 208: 30-43. PMID 10075839 DOI: 10.1006/Dbio.1998.9176 |
0.346 |
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| 1998 |
Nagy L, Thomazy VA, Heyman RA, Davies PJA. Retinoid-induced apoptosis in normal and neoplastic tissues Cell Death and Differentiation. 5: 11-19. PMID 10200441 DOI: 10.1038/Sj.Cdd.4400337 |
0.328 |
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| 1998 |
Tontonoz P, Nagy L, Alvarez JG, Thomazy VA, Evans RM. PPARgamma promotes monocyte/macrophage differentiation and uptake of oxidized LDL. Cell. 93: 241-52. PMID 9568716 DOI: 10.1016/S0092-8674(00)81575-5 |
0.441 |
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| 1998 |
Nagy L, Tontonoz P, Alvarez JG, Chen H, Evans RM. Oxidized LDL regulates macrophage gene expression through ligand activation of PPARgamma. Cell. 93: 229-40. PMID 9568715 DOI: 10.1016/S0092-8674(00)81574-3 |
0.419 |
|
| 1998 |
Lin RJ, Nagy L, Inoue S, Shao W, Miller WH, Evans RM. Role of the histone deacetylase complex in acute promyelocytic leukaemia. Nature. 391: 811-4. PMID 9486654 DOI: 10.1038/35895 |
0.363 |
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| 1997 |
Nagy L, Thomázy VA, Saydak MM, Stein JP, Davies PJ. The promoter of the mouse tissue transglutaminase gene directs tissue-specific, retinoid-regulated and apoptosis-linked expression. Cell Death and Differentiation. 4: 534-47. PMID 14555966 DOI: 10.1038/Sj.Cdd.4400290 |
0.378 |
|
| 1997 |
Chen H, Lin RJ, Schiltz RL, Chakravarti D, Nash A, Nagy L, Privalsky ML, Nakatani Y, Evans RM. Nuclear receptor coactivator ACTR is a novel histone acetyltransferase and forms a multimeric activation complex with P/CAF and CBP/p300. Cell. 90: 569-80. PMID 9267036 DOI: 10.1016/S0092-8674(00)80516-4 |
0.378 |
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| 1997 |
Nagy L, Kao HY, Chakravarti D, Lin RJ, Hassig CA, Ayer DE, Schreiber SL, Evans RM. Nuclear receptor repression mediated by a complex containing SMRT, mSin3A, and histone deacetylase. Cell. 89: 373-80. PMID 9150137 DOI: 10.1016/S0092-8674(00)80218-4 |
0.398 |
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| 1996 |
Yan ZH, Noonan S, Nagy L, Davies PJ, Stein JP. Retinoic acid induction of the tissue transglutaminase promoter is mediated by a novel response element. Molecular and Cellular Endocrinology. 120: 203-12. PMID 8832580 DOI: 10.1016/0303-7207(96)03826-9 |
0.392 |
|
| 1996 |
Nagy L, Thomázy VA, Chandraratna RA, Heyman RA, Davies PJ. Retinoid-regulated expression of BCL-2 and tissue transglutaminase during the differentiation and apoptosis of human myeloid leukemia (HL-60) cells. Leukemia Research. 20: 499-505. PMID 8709622 DOI: 10.1016/0145-2126(95)00118-2 |
0.382 |
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| 1996 |
Nagy L, Saydak M, Shipley N, Lu S, Basilion JP, Yan ZH, Syka P, Chandraratna RA, Stein JP, Heyman RA, Davies PJ. Identification and characterization of a versatile retinoid response element (retinoic acid receptor response element-retinoid X receptor response element) in the mouse tissue transglutaminase gene promoter. The Journal of Biological Chemistry. 271: 4355-65. PMID 8626785 DOI: 10.1074/Jbc.271.8.4355 |
0.409 |
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| 1995 |
Nagy L, Thomázy VA, Shipley GL, Fésüs L, Lamph W, Heyman RA, Chandraratna RA, Davies PJ. Activation of retinoid X receptors induces apoptosis in HL-60 cell lines. Molecular and Cellular Biology. 15: 3540-51. PMID 7791761 DOI: 10.1128/Mcb.15.7.3540 |
0.407 |
|
| 1991 |
Fesus L, Nagy L, Basilion JP, Davies PJA. Retinoic acid receptor transcripts in human umbilical vein endothelial cells. Biochemical and Biophysical Research Communications. 179: 32-38. PMID 1715692 DOI: 10.1016/0006-291X(91)91329-B |
0.38 |
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