Edgar R. Kramer, PD Dr. rer. nat. - Related publications

Affiliations: 
Junior Research Group Development and Maintenance of the Nervous System ZMNH Center For Molecular Neurobiology Hamburg 
Area:
neurotophic factors, dopaminergic system, Parkinson, Drug addiction
Website:
http://www.zmnh.uni-hamburg.de/zmnh/groups/kramer/kramer.html
NOTE: We are testing a new system for identifying relevant work based on semantic analysis that identifies similarities between recently published papers and the current author's publications. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches.
50 most relevant papers in past 60 days:
Year Citation  Score
2021 Mishra AK, Dixit A. Dopaminergic Axons: Key Recitalists in Parkinson's Disease. Neurochemical Research. PMID 34637100 DOI: 10.1007/s11064-021-03464-1   
2021 Anantha J, Goulding SR, Tuboly E, O'Mahony AG, Moloney GM, Lomansey G, McCarthy CM, Collins LM, Sullivan AM, O'Keeffe GW. NME1 Protects Against Neurotoxin-, α-Synuclein- and LRRK2-Induced Neurite Degeneration in Cell Models of Parkinson's Disease. Molecular Neurobiology. PMID 34623600 DOI: 10.1007/s12035-021-02569-6   
2021 Tanguay W, Ducrot C, Giguère N, Bourque MJ, Trudeau LE. Neonatal 6-OHDA lesion of the SNc induces striatal compensatory sprouting from surviving SNc dopaminergic neurons without VTA contribution. The European Journal of Neuroscience. PMID 34470083 DOI: 10.1111/ejn.15437   
2021 de Rus Jacquet A, Tancredi JL, Lemire AL, DeSantis MC, Li WP, O'Shea EK. The LRRK2 G2019S mutation alters astrocyte-to-neuron communication via extracellular vesicles and induces neuron atrophy in a human iPSC-derived model of Parkinson's disease. Elife. 10. PMID 34590578 DOI: 10.7554/eLife.73062   
2021 Sun C, Rosenstock TR, Cohen MA, Sarkar S. Autophagy Dysfunction as a Phenotypic Readout in hiPSC-Derived Neuronal Cell Models of Neurodegenerative Diseases. Methods in Molecular Biology (Clifton, N.J.). PMID 34490597 DOI: 10.1007/7651_2021_420   
2021 Singh A, Upadhayay S, Mehan S. Understanding Abnormal c-JNK/p38MAPK Signaling Overactivation Involved in the Progression of Multiple Sclerosis: Possible Therapeutic Targets and Impact on Neurodegenerative Diseases. Neurotoxicity Research. PMID 34432262 DOI: 10.1007/s12640-021-00401-6   
2021 Van C, Condro MC, Ko HH, Hoang AQ, Zhu R, Lov K, Ricaflanca PT, Diep AL, Nguyen NNM, Lipshutz GS, MacKenzie-Graham A, Waschek JA. Targeted deletion of PAC1 receptors in retinal neurons enhances neuron loss and axonopathy in a model of multiple sclerosis and optic neuritis. Neurobiology of Disease. 105524. PMID 34610465 DOI: 10.1016/j.nbd.2021.105524   
2021 Miressi F, Benslimane N, Favreau F, Rassat M, Richard L, Bourthoumieu S, Laroche C, Magy L, Magdelaine C, Sturtz F, Lia AS, Faye PA. GDAP1 Involvement in Mitochondrial Function and Oxidative Stress, Investigated in a Charcot-Marie-Tooth Model of hiPSCs-Derived Motor Neurons. Biomedicines. 9. PMID 34440148 DOI: 10.3390/biomedicines9080945   
2021 Fajner V, Giavazzi F, Sala S, Oldani A, Martini E, Napoletano F, Parazzoli D, Cesare G, Cerbino R, Maspero E, Vaccari T, Polo S. Hecw controls oogenesis and neuronal homeostasis by promoting the liquid state of ribonucleoprotein particles. Nature Communications. 12: 5488. PMID 34531401 DOI: 10.1038/s41467-021-25809-8   
2021 Appel SH, Beers DR, Zhao W. Amyotrophic lateral sclerosis is a systemic disease: peripheral contributions to inflammation-mediated neurodegeneration. Current Opinion in Neurology. PMID 34402459 DOI: 10.1097/WCO.0000000000000983   
2021 Zhao J, Stevens CH, Boyd AW, Ooi L, Bartlett PF. Role of EphA4 in Mediating Motor Neuron Death in MND. International Journal of Molecular Sciences. 22. PMID 34502339 DOI: 10.3390/ijms22179430   
2021 Follis RM, Tep C, Genaro-Mattos TC, Kim ML, Ryu JC, Morrison VE, Chan JR, Porter N, Carter BD, Yoon SO. Metabolic control of sensory neuron survival by the p75 neurotrophin receptor in Schwann cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 34507952 DOI: 10.1523/JNEUROSCI.3243-20.2021   
2021 Giandomenico SL, Alvarez-Castelao B, Schuman EM. Proteostatic regulation in neuronal compartments. Trends in Neurosciences. PMID 34489114 DOI: 10.1016/j.tins.2021.08.002   
2021 Lee S, Lee W, Yang S, Suh YJ, Hong DG, Chang SC, Kim HS, Lee J. Di--butyl phthalate disrupts neuron maturation in primary rat embryo neurons and male C57BL/6 mice. Journal of Toxicology and Environmental Health. Part A. 1-15. PMID 34488563 DOI: 10.1080/15287394.2021.1973631   
2021 Singh T, Jiao Y, Ferrando LM, Yablonska S, Li F, Horoszko EC, Lacomis D, Friedlander RM, Carlisle DL. Neuronal mitochondrial dysfunction in sporadic amyotrophic lateral sclerosis is developmentally regulated. Scientific Reports. 11: 18916. PMID 34556702 DOI: 10.1038/s41598-021-97928-7   
2021 Chennampally P, Sayed-Zahid A, Soundararajan P, Sharp J, Cox GA, Collins SD, Smith RL. A microfluidic approach to rescue ALS motor neuron degeneration using rapamycin. Scientific Reports. 11: 18168. PMID 34518579 DOI: 10.1038/s41598-021-97405-1   
2021 An J, Chen B, Tian D, Guo Y, Yan Y, Yang H. Regulation of Neurogenesis and Neuronal Differentiation by Natural Compounds. Current Stem Cell Research & Therapy. PMID 34493197 DOI: 10.2174/1574888X16666210907141447   
2021 Sampieri L, Funes Chabán M, Di Giusto P, Rozés-Salvador V, Alvarez C. CREB3L2 Modulates Nerve Growth Factor-Induced Cell Differentiation. Frontiers in Molecular Neuroscience. 14: 650338. PMID 34421533 DOI: 10.3389/fnmol.2021.650338   
2021 Narayanan RK, Brewer MH, Perez-Siles G, Ellis M, Ly C, Burgess A, Neumann B, Nicholson GA, Vucic S, Kennerson ML. Charcot-Marie-tooth disease causing mutation (p.R158H) in pyruvate dehydrogenase kinase 3 (PDK3) affects synaptic transmission, ATP production and causes neurodegeneration in a CMTX6 C. elegans model. Human Molecular Genetics. PMID 34387338 DOI: 10.1093/hmg/ddab228   
2021 Keilhoff G, Ludwig C, Pinkernelle J, Lucas B. Effects of Gynostemma pentaphyllum on spinal cord motor neurons and microglial cells in vitro. Acta Histochemica. 123: 151759. PMID 34425524 DOI: 10.1016/j.acthis.2021.151759   
2021 Hampson E, Tsonou E, Baker MJ, Hornigold DC, Hubbard RE, Massey A, Welch HCE. P-Rex1 Controls Sphingosine 1-Phosphate Receptor Signalling, Morphology, and Cell-Cycle Progression in Neuronal Cells. Cells. 10. PMID 34572121 DOI: 10.3390/cells10092474   
2021 Peng H, Xie P, Liu L, Kuang X, Wang Y, Qu L, Gong H, Jiang S, Li A, Ruan Z, Ding L, Yao Z, Chen C, Chen M, Daigle TL, et al. Morphological diversity of single neurons in molecularly defined cell types. Nature. 598: 174-181. PMID 34616072 DOI: 10.1038/s41586-021-03941-1   
2021 Godin SK, Wagner J, Huang P, Bree D. The role of peripheral nerve signaling in endometriosis. Faseb Bioadvances. 3: 802-813. PMID 34632315 DOI: 10.1096/fba.2021-00063   
2021 Sakai Y, Hanafusa H, Shimizu T, Pastuhov SI, Hisamoto N, Matsumoto K. BRCA1-BARD1 Regulates Axon Regeneration in Concert with the Gqα-DAG Signaling Network. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 41: 2842-2853. PMID 33593852 DOI: 10.1523/JNEUROSCI.1806-20.2021   
2021 Hatayama K, Kim B, Chen X, Lim YP, Davidson JO, Bennet L, Gunn AJ, Stonestreet BS. Changes in Cellular Localization of Inter-Alpha Inhibitor Proteins after Cerebral Ischemia in the Near-Term Ovine Fetus. International Journal of Molecular Sciences. 22. PMID 34639091 DOI: 10.3390/ijms221910751   
2021 Yoon G, Lim YH, Jo D, Ryu J, Song J, Kim YK. Obesity-linked circular RNA circTshz2-2 regulates the neuronal cell cycle and spatial memory in the brain. Molecular Psychiatry. PMID 34561612 DOI: 10.1038/s41380-021-01303-x   
2021 Markworth R, Bähr M, Burk K. Held Up in Traffic-Defects in the Trafficking Machinery in Charcot-Marie-Tooth Disease. Frontiers in Molecular Neuroscience. 14: 695294. PMID 34483837 DOI: 10.3389/fnmol.2021.695294   
2021 Bassil R, Shields K, Granger K, Zein I, Ng S, Chih B. Improved modeling of human AD with an automated culturing platform for iPSC neurons, astrocytes and microglia. Nature Communications. 12: 5220. PMID 34471104 DOI: 10.1038/s41467-021-25344-6   
2021 Kray KM, McGovern VL, Chugh D, Arnold WD, Burghes AHM. Dual SMN inducing therapies can rescue survival and motor unit function in symptomatic ∆7SMA mice. Neurobiology of Disease. 159: 105488. PMID 34425216 DOI: 10.1016/j.nbd.2021.105488   
2021 Kato Y, Sakamoto K. Niclosamide affects intracellular TDP-43 distribution in motor neurons, activates mitophagy, and attenuates morphological changes under stress. Journal of Bioscience and Bioengineering. PMID 34429248 DOI: 10.1016/j.jbiosc.2021.06.015   
2021 Arthur-Farraj P, Coleman MP. Lessons from Injury: How Nerve Injury Studies Reveal Basic Biological Mechanisms and Therapeutic Opportunities for Peripheral Nerve Diseases. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. PMID 34595734 DOI: 10.1007/s13311-021-01125-3   
2021 Gorostieta-Salas E, Moreno-Blas D, Gerónimo-Olvera C, Cisneros B, Court FA, Castro-Obregón S. Enhanced Activity of Exportin-1/CRM1 in Neurons Contributes to Autophagy Dysfunction and Senescent Features in Old Mouse Brain. Oxidative Medicine and Cellular Longevity. 2021: 6682336. PMID 34434486 DOI: 10.1155/2021/6682336   
2021 Henningsen JB, Soylu-Kucharz R, Björkqvist M, Petersén Å. Effects of excitotoxicity in the hypothalamus in transgenic mouse models of Huntington disease. Heliyon. 7: e07808. PMID 34458633 DOI: 10.1016/j.heliyon.2021.e07808   
2021 Schnatz A, Müller C, Brahmer A, Krämer-Albers EM. Extracellular Vesicles in neural cell interaction and CNS homeostasis. Faseb Bioadvances. 3: 577-592. PMID 34377954 DOI: 10.1096/fba.2021-00035   
2021 Salazar K, Espinoza F, Cerda-Gallardo G, Ferrada L, Magdalena R, Ramírez E, Ulloa V, Saldivia N, Troncoso N, Oviedo MJ, Barahona MJ, Martínez F, Nualart F. SVCT2 Overexpression and Ascorbic Acid Uptake Increase Cortical Neuron Differentiation, Which Is Dependent on Vitamin C Recycling between Neurons and Astrocytes. Antioxidants (Basel, Switzerland). 10. PMID 34573045 DOI: 10.3390/antiox10091413   
2021 Martínez-Rojas VA, Arosio D, Pennuto M, Musio C. Clenbuterol-sensitive delayed outward potassium currents in a cell model of spinal and bulbar muscular atrophy. Pflugers Archiv : European Journal of Physiology. 473: 1213-1227. PMID 34021780 DOI: 10.1007/s00424-021-02559-6   
2021 Lee TH, Liu PS, Wang SJ, Tsai MM, Shanmugam V, Hsieh HL. Bradykinin, as a Reprogramming Factor, Induces Transdifferentiation of Brain Astrocytes into Neuron-like Cells. Biomedicines. 9. PMID 34440126 DOI: 10.3390/biomedicines9080923   
2021 Griggs RB, Nguyen DVM, Yermakov LM, Jaber JM, Shelby JN, Steinbrunner JK, Miller JA, Gonzalez-Islas C, Wenner P, Susuki K. The type 2 diabetes factor methylglyoxal mediates axon initial segment shortening and alters neuronal function at the cellular and network levels. Eneuro. PMID 34531281 DOI: 10.1523/ENEURO.0201-21.2021   
2021 Richard EM, Bakhtiari S, Marsh APL, Kaiyrzhanov R, Wagner M, Shetty S, Pagnozzi A, Nordlie SM, Guida BS, Cornejo P, Magee H, Liu J, Norton BY, Webster RI, Worgan L, et al. Bi-allelic variants in SPATA5L1 lead to intellectual disability, spastic-dystonic cerebral palsy, epilepsy, and hearing loss. American Journal of Human Genetics. 108: 2006-2016. PMID 34626583 DOI: 10.1016/j.ajhg.2021.08.003   
2021 Jin H, Qi F, Chu F, Liu C, Qian T, Zeng W, Wang Q, Wang X, Xiao J. Morin improves functional recovery after spinal cord injury in rats by enhancing axon regeneration via the Nrf2/HO-1 pathway. Phytotherapy Research : Ptr. PMID 34431562 DOI: 10.1002/ptr.7234   
2021 Jaudon F, Albini M, Ferroni S, Benfenati F, Cesca F. A developmental stage- and Kidins220-dependent switch in astrocyte responsiveness to brain-derived neurotrophic factor. Journal of Cell Science. 134. PMID 34415036 DOI: 10.1242/jcs.258419   
2021 Jansen J, Scott M, Amjad E, Stumpf A, Lackey KH, Caldwell KA, Park HA. Bcl-xL Is Required by Primary Hippocampal Neurons during Development to Support Local Energy Metabolism at Neurites. Biology. 10. PMID 34440004 DOI: 10.3390/biology10080772   
2021 Yamasaki Y, Lim YM, Minami R, Tsuda L. A splicing variant of Charlatan, a Drosophila REST-like molecule, preferentially localizes to axons. Biochemical and Biophysical Research Communications. 578: 35-41. PMID 34536827 DOI: 10.1016/j.bbrc.2021.09.002   
2021 An J, He Y, Yin J, Ding Z, Han Q, Chen Y, Wang Q, Chai Z, Yu J, Song L, Xiao B, Ma C. Temporal and spatial evolution of various functional neurons during demyelination induced by cuprizone. Journal of Neurophysiology. PMID 34669500 DOI: 10.1152/jn.00224.2021   
2021 Ronzano R, Roux T, Thetiot M, Aigrot MS, Richard L, Lejeune FX, Mazuir E, Vallat JM, Lubetzki C, Desmazières A. Microglia-neuron interaction at nodes of Ranvier depends on neuronal activity through potassium release and contributes to remyelination. Nature Communications. 12: 5219. PMID 34471138 DOI: 10.1038/s41467-021-25486-7   
2021 Koh A, Sarusie MV, Ohmer J, Fischer U, Winkler C, Wohland T. Fluorescence Correlation Spectroscopy Reveals Survival Motor Neuron Oligomerization but No Active Transport in Motor Axons of a Zebrafish Model for Spinal Muscular Atrophy. Frontiers in Cell and Developmental Biology. 9: 639904. PMID 34458251 DOI: 10.3389/fcell.2021.639904   
2021 Stern S, Hilton BJ, Burnside ER, Dupraz S, Handley EE, Gonyer JM, Brakebusch C, Bradke F. RhoA drives actin compaction to restrict axon regeneration and astrocyte reactivity after CNS injury. Neuron. PMID 34508667 DOI: 10.1016/j.neuron.2021.08.014   
2021 Li X, Pan Y, Gui J, Fang Z, Huang D, Luo H, Cheng L, Chen H, Song X, Jiang L. The Role and Mechanism of AMIGO3 in the Formation of Aberrant Neural Circuits After Status Convulsion in Immature Mice. Frontiers in Molecular Neuroscience. 14: 748115. PMID 34650403 DOI: 10.3389/fnmol.2021.748115   
2021 Peters OM, Smith GA. A nod and a Wnk to axon branching and destruction. Neuron. 109: 2799-2802. PMID 34534451 DOI: 10.1016/j.neuron.2021.08.027   
2021 Huang L, Fung E, Bose S, Popp A, Böser P, Memmott J, Kutskova YA, Miller R, Tarcsa E, Klein C, Veldman GM, Mueller BK, Cui YF. Elezanumab, a clinical stage human monoclonal antibody that selectively targets repulsive guidance molecule A to promote neuroregeneration and neuroprotection in neuronal injury and demyelination models. Neurobiology of Disease. 105492. PMID 34478849 DOI: 10.1016/j.nbd.2021.105492