Year |
Citation |
Score |
2020 |
Iwase M, Tokiwa S, Seno S, Mukai T, Yeh YS, Takahashi H, Nomura W, Jheng HF, Matsumura S, Kusudo T, Osato N, Matsuda H, Inoue K, Kawada T, Goto T. Glycerol kinase stimulates uncoupling protein 1 expression by regulating fatty acid metabolism in beige adipocytes. The Journal of Biological Chemistry. PMID 32273338 DOI: 10.1074/Jbc.Ra119.011658 |
0.313 |
|
2019 |
Kobayakawa T, Ebihara K, Honda Y, Fujino M, Nomura W, Yamamoto N, Murakami T, Tamamura H. C34 Dimeric Derivatives Utilizing Disulfide Bridges as Novel HIV-1 Fusion Inhibitors. Chembiochem : a European Journal of Chemical Biology. PMID 31012222 DOI: 10.1002/Cbic.201900187 |
0.373 |
|
2019 |
Sakyiamah MM, Nomura W, Kobayakawa T, Tamamura H. Development of a NanoBRET-Based Sensitive Screening Method for CXCR4 Ligands. Bioconjugate Chemistry. PMID 30973227 DOI: 10.1021/Acs.Bioconjchem.9B00182 |
0.321 |
|
2019 |
Sakyiamah MM, Kobayakawa T, Fujino M, Konno M, Narumi T, Tanaka T, Nomura W, Yamamoto N, Murakami T, Tamamura H. Design, synthesis and biological evaluation of low molecular weight CXCR4 ligands. Bioorganic & Medicinal Chemistry. PMID 30772128 DOI: 10.1016/J.Bmc.2019.02.013 |
0.376 |
|
2019 |
Yuliana A, Daijo A, Jheng HF, Kwon J, Nomura W, Takahashi H, Ara T, Kawada T, Goto T. Endoplasmic Reticulum Stress Impaired Uncoupling Protein 1 Expression via the Suppression of Peroxisome Proliferator-Activated Receptor γ Binding Activity in Mice Beige Adipocytes. International Journal of Molecular Sciences. 20. PMID 30641938 DOI: 10.3390/Ijms20020274 |
0.301 |
|
2018 |
Matsuda K, Kobayakawa T, Tsuchiya K, Hattori SH, Nomura W, Gatanaga H, Yoshimura K, Oka S, Endo Y, Tamamura H, Mitsuya H, Maeda K. Benzolactam-related compounds promote apoptosis of HIV-infected human cells via protein kinase C-induced HIV latency reversal. The Journal of Biological Chemistry. PMID 30413535 DOI: 10.1074/Jbc.Ra118.005798 |
0.347 |
|
2018 |
Toyama K, Kobayakawa T, Nomura W, Tamamura H. Inhibition of EGFR Activation by Bivalent Ligands Based on a Cyclic Peptide Mimicking the Dimerization Arm Structure of EGFR. Chemical & Pharmaceutical Bulletin. 66: 1083-1089. PMID 30381661 DOI: 10.1248/Cpb.C18-00539 |
0.311 |
|
2018 |
Nomura W. Development of Toolboxes for Precision Genome/epigenome Editing and Imaging of Epigenetics. Chemical Record (New York, N.Y.). PMID 30066981 DOI: 10.1002/Tcr.201800036 |
0.303 |
|
2018 |
Toyama K, Nomura W, Kobayakawa T, Tamamura H. Delivery of a Pro-apoptotic Peptide to EGFR-positive Cancer Cells by a Cyclic Peptide Mimicking the Dimerization Arm Structure of EGFR. Bioconjugate Chemistry. PMID 29763296 DOI: 10.1021/Acs.Bioconjchem.8B00250 |
0.313 |
|
2018 |
Kobayakawa T, Matsuzaki Y, Hozumi K, Nomura W, Nomizu M, Tamamura H. Synthesis of a Chloroalkene Dipeptide Isostere-Containing Peptidomimetic and Its Biological Application. Acs Medicinal Chemistry Letters. 9: 6-10. PMID 29348803 DOI: 10.1021/Acsmedchemlett.7B00234 |
0.316 |
|
2017 |
Nomura W. Creation of Functional Molecules Based on Biomolecular Interactions; Development toward Chemical Biology. Yakugaku Zasshi : Journal of the Pharmaceutical Society of Japan. 137: 1223-1231. PMID 28966263 DOI: 10.1248/Yakushi.17-00125 |
0.367 |
|
2017 |
Ohashi N, Kobayashi R, Nomura W, Kobayakawa T, Czikora A, Herold B, Lewin N, Blumberg PM, Tamamura H. Synthesis and evaluation of dimeric derivatives of diacylglycerol-lactones as PKC ligands. Bioconjugate Chemistry. PMID 28671468 DOI: 10.1021/Acs.Bioconjchem.7B00299 |
0.343 |
|
2017 |
Tanaka T, Aoki T, Nomura W, Tamamura H. Bivalent 14-mer peptide ligands of CXCR4 with polyproline linkers with anti-chemotactic activity against Jurkat cells. Journal of Peptide Science : An Official Publication of the European Peptide Society. PMID 28078743 DOI: 10.1002/Psc.2946 |
0.362 |
|
2016 |
Mizuguchi T, Ohashi N, Matsumoto D, Hashimoto C, Nomura W, Yamamoto N, Murakami T, Tamamura H. Development of Anti-HIV Peptides Based on a Viral Capsid Protein. Biopolymers. PMID 27428649 DOI: 10.1002/Bip.22920 |
0.383 |
|
2016 |
Toyama K, Mizuguchi T, Nomura W, Tamamura H. Functional evaluation of fluorescein-labeled derivatives of a peptide inhibitor of the EGF receptor dimerization. Bioorganic & Medicinal Chemistry. PMID 27283787 DOI: 10.1016/J.Bmc.2016.05.026 |
0.335 |
|
2016 |
Ohashi N, Harada S, Mizuguchi T, Irahara Y, Yamada Y, Kotani M, Nomura W, Matsushita S, Yoshimura K, Tamamura H. Small-Molecule CD4 Mimics Containing Mono-cyclohexyl Moieties as HIV Entry Inhibitors. Chemmedchem. PMID 26891461 DOI: 10.1002/Cmdc.201500590 |
0.349 |
|
2015 |
Mizuguchi T, Harada S, Miura T, Ohashi N, Narumi T, Mori H, Irahara Y, Yamada Y, Nomura W, Matsushita S, Yoshimura K, Tamamura H. A minimally cytotoxic CD4 mimic as an HIV entry inhibitor. Bioorganic & Medicinal Chemistry Letters. PMID 26706175 DOI: 10.1016/J.Bmcl.2015.11.103 |
0.322 |
|
2015 |
Nomura W, Mizuguchi T, Tamamura H. Multimerized HIV-gp41-derived Peptides as Fusion Inhibitors and Vaccines†. Biopolymers. PMID 26583370 DOI: 10.1002/Bip.22782 |
0.387 |
|
2015 |
Nomura W, Aikawa H, Taketomi S, Tanabe M, Mizuguchi T, Tamamura H. Exploration of labeling by near infrared dyes of the polyproline linker for bivalent-type CXCR4 ligands. Bioorganic & Medicinal Chemistry. PMID 26453409 DOI: 10.1016/J.Bmc.2015.09.040 |
0.309 |
|
2015 |
Nomura W, Koseki T, Ohashi N, Mizuguchi T, Tamamura H. Trivalent ligands for CXCR4 bearing polyproline linkers show specific recognition for cells with increased CXCR4 expression. Organic & Biomolecular Chemistry. 13: 8734-9. PMID 26186480 DOI: 10.1039/C5Ob00891C |
0.315 |
|
2015 |
Mizuguchi T, Ohashi N, Nomura W, Komoriya M, Hashimoto C, Yamamoto N, Murakami T, Tamamura H. Anti-HIV screening for cell-penetrating peptides using chloroquine and identification of anti-HIV peptides derived from matrix proteins. Bioorganic & Medicinal Chemistry. PMID 26094944 DOI: 10.1016/J.Bmc.2015.06.020 |
0.385 |
|
2015 |
Nomura W, Ohashi N, Mori A, Tamamura H. An In-Cell Fluorogenic Tag-Probe System for Protein Dynamics Imaging Enabled by Cell-Penetrating Peptides. Bioconjugate Chemistry. 26: 1080-5. PMID 25938941 DOI: 10.1021/Acs.Bioconjchem.5B00131 |
0.346 |
|
2014 |
Ohashi N, Nomura W, Minato N, Tamamura H. Screening for protein kinase C ligands using fluorescence resonance energy transfer. Chemical & Pharmaceutical Bulletin. 62: 1019-25. PMID 25109829 DOI: 10.1248/Cpb.C14-00419 |
0.337 |
|
2014 |
Yamamoto J, Maeda N, Komiya C, Tanaka T, Denda M, Ebisuno K, Nomura W, Tamamura H, Sato Y, Yamauchi A, Shigenaga A, Otaka A. Development of a fluoride-responsive amide bond cleavage device that is potentially applicable to a traceable linker Tetrahedron. 70: 5122-5127. DOI: 10.1016/J.Tet.2014.05.110 |
0.327 |
|
2013 |
Hashimoto C, Narumi T, Otsuki H, Hirota Y, Arai H, Yoshimura K, Harada S, Ohashi N, Nomura W, Miura T, Igarashi T, Matsushita S, Tamamura H. A CD4 mimic as an HIV entry inhibitor: pharmacokinetics. Bioorganic & Medicinal Chemistry. 21: 7884-9. PMID 24189188 DOI: 10.1016/J.Bmc.2013.10.005 |
0.316 |
|
2013 |
Hashimoto C, Nomura W, Narumi T, Fujino M, Nakahara T, Yamamoto N, Murakami T, Tamamura H. CXCR4-derived synthetic peptides inducing anti-HIV-1 antibodies. Bioorganic & Medicinal Chemistry. 21: 6878-85. PMID 24119449 DOI: 10.1016/J.Bmc.2013.09.037 |
0.372 |
|
2013 |
Hashimoto C, Nomura W, Narumi T, Fujino M, Tsutsumi H, Haseyama M, Yamamoto N, Murakami T, Tamamura H. Anti-HIV-1 peptide derivatives based on the HIV-1 Co-receptor CXCR4. Chemmedchem. 8: 1668-72. PMID 24039179 DOI: 10.1002/Cmdc.201300289 |
0.385 |
|
2013 |
Nomura W, Aikawa H, Ohashi N, Urano E, Métifiot M, Fujino M, Maddali K, Ozaki T, Nozue A, Narumi T, Hashimoto C, Tanaka T, Pommier Y, Yamamoto N, Komano JA, et al. Cell-permeable stapled peptides based on HIV-1 integrase inhibitors derived from HIV-1 gene products. Acs Chemical Biology. 8: 2235-44. PMID 23898787 DOI: 10.1021/Cb400495H |
0.387 |
|
2013 |
Ohashi N, Nomura W, Narumi T, Tamamura H. Peptide-based ligand screening and functional analysis of protein kinase C. Biopolymers. 100: 613-20. PMID 23897302 DOI: 10.1002/Bip.22324 |
0.358 |
|
2013 |
Nomura W, Hashimoto C, Suzuki T, Ohashi N, Fujino M, Murakami T, Yamamoto N, Tamamura H. Multimerized CHR-derived peptides as HIV-1 fusion inhibitors. Bioorganic & Medicinal Chemistry. 21: 4452-8. PMID 23800723 DOI: 10.1016/J.Bmc.2013.05.060 |
0.39 |
|
2013 |
Narumi T, Arai H, Yoshimura K, Harada S, Hirota Y, Ohashi N, Hashimoto C, Nomura W, Matsushita S, Tamamura H. CD4 mimics as HIV entry inhibitors: lead optimization studies of the aromatic substituents. Bioorganic & Medicinal Chemistry. 21: 2518-26. PMID 23535561 DOI: 10.1016/J.Bmc.2013.02.041 |
0.333 |
|
2013 |
Narumi T, Aikawa H, Tanaka T, Hashimoto C, Ohashi N, Nomura W, Kobayakawa T, Takano H, Hirota Y, Murakami T, Yamamoto N, Tamamura H. Low-molecular-weight CXCR4 ligands with variable spacers. Chemmedchem. 8: 118-24. PMID 23086703 DOI: 10.1002/Cmdc.201200390 |
0.333 |
|
2012 |
Narumi T, Tanaka T, Hashimoto C, Nomura W, Aikawa H, Sohma A, Itotani K, Kawamata M, Murakami T, Yamamoto N, Tamamura H. Pharmacophore-based small molecule CXCR4 ligands. Bioorganic & Medicinal Chemistry Letters. 22: 4169-72. PMID 22579418 DOI: 10.1016/J.Bmcl.2012.04.032 |
0.374 |
|
2012 |
Hashimoto C, Nomura W, Ohya A, Urano E, Miyauchi K, Narumi T, Aikawa H, Komano JA, Yamamoto N, Tamamura H. Evaluation of a synthetic C34 trimer of HIV-1 gp41 as AIDS vaccines. Bioorganic & Medicinal Chemistry. 20: 3287-91. PMID 22507207 DOI: 10.1016/J.Bmc.2012.03.050 |
0.332 |
|
2012 |
Nomura W, Masuda A, Ohba K, Urabe A, Ito N, Ryo A, Yamamoto N, Tamamura H. Effects of DNA binding of the zinc finger and linkers for domain fusion on the catalytic activity of sequence-specific chimeric recombinases determined by a facile fluorescent system. Biochemistry. 51: 1510-7. PMID 22304662 DOI: 10.1021/Bi201878X |
0.319 |
|
2012 |
Narumi T, Komoriya M, Hashimoto C, Wu H, Nomura W, Suzuki S, Tanaka T, Chiba J, Yamamoto N, Murakami T, Tamamura H. Conjugation of cell-penetrating peptides leads to identification of anti-HIV peptides from matrix proteins. Bioorganic & Medicinal Chemistry. 20: 1468-74. PMID 22277590 DOI: 10.1016/J.Bmc.2011.12.055 |
0.372 |
|
2012 |
Nomura W, Hashimoto C, Ohya A, Miyauchi K, Urano E, Tanaka T, Narumi T, Nakahara T, Komano JA, Yamamoto N, Tamamura H. A synthetic C34 trimer of HIV-1 gp41 shows significant increase in inhibition potency. Chemmedchem. 7: 205-8. PMID 22247043 DOI: 10.1002/Cmdc.201100542 |
0.324 |
|
2012 |
Nomura W, Hashimoto C, Ohya A, Miyauchi K, Urano E, Tanaka T, Narumi T, Nakahara T, Komano JA, Yamamoto N, Tamamura H. Corrigendum: A Synthetic C34 Trimer of HIV-1 gp41 Shows Significant Increase in Inhibition Potency Chemmedchem. 7: 546-546. DOI: 10.1002/Cmdc.201200114 |
0.324 |
|
2011 |
Nomura W, Narumi T, Ohashi N, Serizawa Y, Lewin NE, Blumberg PM, Furuta T, Tamamura H. Synthetic caged DAG-lactones for photochemically controlled activation of protein kinase C. Chembiochem : a European Journal of Chemical Biology. 12: 535-9. PMID 22238145 DOI: 10.1002/Cbic.201000670 |
0.323 |
|
2011 |
Narumi T, Arai H, Yoshimura K, Harada S, Nomura W, Matsushita S, Tamamura H. Small molecular CD4 mimics as HIV entry inhibitors. Bioorganic & Medicinal Chemistry. 19: 6735-42. PMID 22014753 DOI: 10.1016/J.Bmc.2011.09.045 |
0.325 |
|
2011 |
Nomura W, Ohashi N, Okuda Y, Narumi T, Ikura T, Ito N, Tamamura H. Fluorescence-quenching screening of protein kinase C ligands with an environmentally sensitive fluorophore. Bioconjugate Chemistry. 22: 923-30. PMID 21434694 DOI: 10.1021/Bc100567K |
0.329 |
|
2011 |
Tanaka T, Narumi T, Ozaki T, Sohma A, Ohashi N, Hashimoto C, Itotani K, Nomura W, Murakami T, Yamamoto N, Tamamura H. Azamacrocyclic metal complexes as CXCR4 antagonists. Chemmedchem. 6: 834-9. PMID 21312334 DOI: 10.1002/Cmdc.201000548 |
0.348 |
|
2011 |
Ohashi N, Nomura W, Narumi T, Lewin NE, Itotani K, Blumberg PM, Tamamura H. Fluorescent-responsive synthetic C1b domains of protein kinase Cδ as reporters of specific high-affinity ligand binding. Bioconjugate Chemistry. 22: 82-7. PMID 21175182 DOI: 10.1021/Bc100414A |
0.337 |
|
2010 |
Narumi T, Ochiai C, Yoshimura K, Harada S, Tanaka T, Nomura W, Arai H, Ozaki T, Ohashi N, Matsushita S, Tamamura H. CD4 mimics targeting the HIV entry mechanism and their hybrid molecules with a CXCR4 antagonist. Bioorganic & Medicinal Chemistry Letters. 20: 5853-8. PMID 20728351 DOI: 10.1016/J.Bmcl.2010.07.106 |
0.31 |
|
2010 |
Suzuki S, Maddali K, Hashimoto C, Urano E, Ohashi N, Tanaka T, Ozaki T, Arai H, Tsutsumi H, Narumi T, Nomura W, Yamamoto N, Pommier Y, Komano JA, Tamamura H. Peptidic HIV integrase inhibitors derived from HIV gene products: structure-activity relationship studies. Bioorganic & Medicinal Chemistry. 18: 6771-5. PMID 20708407 DOI: 10.1016/J.Bmc.2010.07.050 |
0.388 |
|
2010 |
Suzuki S, Urano E, Hashimoto C, Tsutsumi H, Nakahara T, Tanaka T, Nakanishi Y, Maddali K, Han Y, Hamatake M, Miyauchi K, Pommier Y, Beutler JA, Sugiura W, Fuji H, ... ... Nomura W, et al. Peptide HIV-1 integrase inhibitors from HIV-1 gene products. Journal of Medicinal Chemistry. 53: 5356-60. PMID 20586421 DOI: 10.1021/Jm1003528 |
0.364 |
|
2010 |
Nomura W, Mino T, Narumi T, Ohashi N, Masuda A, Hashimoto C, Tsutsumi H, Tamamura H. Development of crosslink-type tag-probe pairs for fluorescent imaging of proteins. Biopolymers. 94: 843-52. PMID 20564030 DOI: 10.1002/Bip.21444 |
0.341 |
|
2010 |
Nakahara T, Nomura W, Ohba K, Ohya A, Tanaka T, Hashimoto C, Narumi T, Murakami T, Yamamoto N, Tamamura H. Remodeling of dynamic structures of HIV-1 envelope proteins leads to synthetic antigen molecules inducing neutralizing antibodies. Bioconjugate Chemistry. 21: 709-14. PMID 20359196 DOI: 10.1021/Bc900502Z |
0.338 |
|
2010 |
Yamada Y, Ochiai C, Yoshimura K, Tanaka T, Ohashi N, Narumi T, Nomura W, Harada S, Matsushita S, Tamamura H. CD4 mimics targeting the mechanism of HIV entry. Bioorganic & Medicinal Chemistry Letters. 20: 354-8. PMID 19926478 DOI: 10.1016/J.Bmcl.2009.10.098 |
0.323 |
|
2009 |
Tsutsumi H, Nomura W, Abe S, Mino T, Masuda A, Ohashi N, Tanaka T, Ohba K, Yamamoto N, Akiyoshi K, Tamamura H. Fluorogenically active leucine zipper peptides as tag-probe pairs for protein imaging in living cells. Angewandte Chemie (International Ed. in English). 48: 9164-6. PMID 19876989 DOI: 10.1002/Anie.200903183 |
0.336 |
|
2009 |
Tanaka T, Nomura W, Narumi T, Esaka A, Oishi S, Ohashi N, Itotani K, Evans BJ, Wang ZX, Peiper SC, Fujii N, Tamamura H. Structure-activity relationship study on artificial CXCR4 ligands possessing the cyclic pentapeptide scaffold: the exploration of amino acid residues of pentapeptides by substitutions of several aromatic amino acids. Organic & Biomolecular Chemistry. 7: 3805-9. PMID 19707686 DOI: 10.1039/B908286G |
0.346 |
|
2009 |
Ohashi N, Nomura W, Kato M, Narumi T, Lewin NE, Blumberg PM, Tamamura H. Synthesis of protein kinase Cdelta C1b domain by native chemical ligation methodology and characterization of its folding and ligand binding. Journal of Peptide Science : An Official Publication of the European Peptide Society. 15: 642-6. PMID 19672879 DOI: 10.1002/Psc.1161 |
0.332 |
|
2008 |
Tanaka T, Tsutsumi H, Nomura W, Tanabe Y, Ohashi N, Esaka A, Ochiai C, Sato J, Itotani K, Murakami T, Ohba K, Yamamoto N, Fujii N, Tamamura H. Structure-activity relationship study of CXCR4 antagonists bearing the cyclic pentapeptide scaffold: identification of the new pharmacophore. Organic & Biomolecular Chemistry. 6: 4374-7. PMID 19005596 DOI: 10.1039/B812029C |
0.344 |
|
2008 |
Nomura W, Maeta K, Kita K, Izawa S, Inoue Y. Role of Gcn4 for adaptation to methylglyoxal in Saccharomyces cerevisiae: methylglyoxal attenuates protein synthesis through phosphorylation of eIF2alpha. Biochemical and Biophysical Research Communications. 376: 738-42. PMID 18812164 DOI: 10.1016/J.Bbrc.2008.09.063 |
0.308 |
|
2008 |
Nomura W, Tanabe Y, Tsutsumi H, Tanaka T, Ohba K, Yamamoto N, Tamamura H. Fluorophore labeling enables imaging and evaluation of specific CXCR4-ligand interaction at the cell membrane for fluorescence-based screening. Bioconjugate Chemistry. 19: 1917-20. PMID 18707146 DOI: 10.1021/Bc800216P |
0.331 |
|
2007 |
Nomura W, Sugiura Y. Design and synthesis of artificial zinc finger proteins. Methods in Molecular Biology (Clifton, N.J.). 352: 83-93. PMID 17041260 DOI: 10.1385/1-59745-187-8:83 |
0.308 |
|
2005 |
Hirata T, Nomura W, Imanishi M, Sugiura Y. Effects of linking 15-zinc finger domains on DNA binding specificity and multiple DNA binding modes. Bioorganic & Medicinal Chemistry Letters. 15: 2197-201. PMID 15837293 DOI: 10.1016/J.Bmcl.2005.03.040 |
0.316 |
|
2003 |
Nomura W, Sugiura Y. Effects of length and position of an extended linker on sequence-selective DNA recognition of zinc finger peptides. Biochemistry. 42: 14805-13. PMID 14674754 DOI: 10.1021/Bi035446H |
0.33 |
|
2003 |
Nomura W, Nagaoka M, Shiraishi Y, Sugiura Y. Influence of TFIIIA-type linker at the N- or C-terminal of nine-zinc finger protein on DNA-binding site. Biochemical and Biophysical Research Communications. 300: 87-92. PMID 12480525 DOI: 10.1016/S0006-291X(02)02792-4 |
0.313 |
|
2002 |
Nagaoka M, Shiraishi Y, Uno Y, Nomura W, Sugiura Y. Interconversion between serine and aspartic acid in the alpha helix of the N-terminal zinc finger of Sp1: implication for general recognition code and for design of novel zinc finger peptide recognizing complementary strand. Biochemistry. 41: 8819-25. PMID 12102624 DOI: 10.1021/Bi0256429 |
0.316 |
|
2001 |
Nagaoka M, Kaji T, Imanishi M, Hori Y, Nomura W, Sugiura Y. Multiconnection of identical zinc finger: implication for DNA binding affinity and unit modulation of the three zinc finger domain. Biochemistry. 40: 2932-41. PMID 11258905 DOI: 10.1021/Bi001762+ |
0.328 |
|
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