Karin Danzer - Publications

2008-2011 Neurology Massachusetts General Hospital, Boston, MA 

24/51 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Brenner D, Müller K, Wieland T, Weydt P, Böhm S, Lulé D, Hübers A, Neuwirth C, Weber M, Borck G, Wahlqvist M, Danzer KM, Volk AE, Meitinger T, Strom TM, et al. NEK1 mutations in familial amyotrophic lateral sclerosis. Brain : a Journal of Neurology. 139: e28. PMID 26945885 DOI: 10.1093/brain/aww033  0.64
2015 Stuendl A, Kunadt M, Kruse N, Bartels C, Moebius W, Danzer KM, Mollenhauer B, Schneider A. Induction of α-synuclein aggregate formation by CSF exosomes from patients with Parkinson's disease and dementia with Lewy bodies. Brain : a Journal of Neurology. PMID 26647156 DOI: 10.1093/brain/awv346  0.64
2015 Helferich AM, Ruf WP, Grozdanov V, Freischmidt A, Feiler MS, Zondler L, Ludolph AC, McLean PJ, Weishaupt JH, Danzer KM. α-synuclein interacts with SOD1 and promotes its oligomerization. Molecular Neurodegeneration. 10: 66. PMID 26643113 DOI: 10.1186/s13024-015-0062-3  0.64
2015 Feiler MS, Strobel B, Freischmidt A, Helferich AM, Kappel J, Brewer BM, Li D, Thal DR, Walther P, Ludolph AC, Danzer KM, Weishaupt JH. TDP-43 is intercellularly transmitted across axon terminals. The Journal of Cell Biology. 211: 897-911. PMID 26598621 DOI: 10.1083/jcb.201504057  0.64
2015 Bliederhaeuser C, Grozdanov V, Speidel A, Zondler L, Ruf WP, Bayer H, Kiechle M, Feiler MS, Freischmidt A, Brenner D, Witting A, Hengerer B, Fändrich M, Ludolph AC, Weishaupt JH, ... ... Danzer KM, et al. Age-dependent defects of alpha-synuclein oligomer uptake in microglia and monocytes. Acta Neuropathologica. PMID 26576561 DOI: 10.1007/s00401-015-1504-2  0.64
2015 Marroquin N, Stranz S, Müller K, Wieland T, Ruf WP, Brockmann SJ, Danzer KM, Borck G, Hübers A, Weydt P, Meitinger T, Strom TM, Rosenbohm A, Ludolph AC, Weishaupt JH. Screening for CHCHD10 mutations in a large cohort of sporadic ALS patients: no evidence for pathogenicity of the p.P34S variant. Brain : a Journal of Neurology. PMID 26362909 DOI: 10.1093/brain/awv218  0.64
2015 Freischmidt A, Müller K, Zondler L, Weydt P, Mayer B, von Arnim CA, Hübers A, Dorst J, Otto M, Holzmann K, Ludolph AC, Danzer KM, Weishaupt JH. Serum microRNAs in sporadic amyotrophic lateral sclerosis. Neurobiology of Aging. 36: 2660.e15-20. PMID 26142125 DOI: 10.1016/j.neurobiolaging.2015.06.003  0.64
2015 von Einem B, Wahler A, Schips T, Serrano-Pozo A, Proepper C, Boeckers TM, Rueck A, Wirth T, Hyman BT, Danzer KM, Thal DR, von Arnim CA. The Golgi-Localized γ-Ear-Containing ARF-Binding (GGA) Proteins Alter Amyloid-β Precursor Protein (APP) Processing through Interaction of Their GAE Domain with the Beta-Site APP Cleaving Enzyme 1 (BACE1). Plos One. 10: e0129047. PMID 26053850 DOI: 10.1371/journal.pone.0129047  0.64
2015 Freischmidt A, Wieland T, Richter B, Ruf W, Schaeffer V, Müller K, Marroquin N, Nordin F, Hübers A, Weydt P, Pinto S, Press R, Millecamps S, Molko N, Bernard E, ... ... Danzer KM, et al. Haploinsufficiency of TBK1 causes familial ALS and fronto-temporal dementia. Nature Neuroscience. 18: 631-6. PMID 25803835 DOI: 10.1038/nn.4000  0.64
2015 Kunadt M, Eckermann K, Stuendl A, Gong J, Russo B, Strauss K, Rai S, Kügler S, Falomir Lockhart L, Schwalbe M, Krumova P, Oliveira LM, Bähr M, Möbius W, Levin J, ... ... Danzer KM, et al. Extracellular vesicle sorting of α-Synuclein is regulated by sumoylation. Acta Neuropathologica. 129: 695-713. PMID 25778619 DOI: 10.1007/s00401-015-1408-1  0.64
2015 Eschbach J, von Einem B, Müller K, Bayer H, Scheffold A, Morrison BE, Rudolph KL, Thal DR, Witting A, Weydt P, Otto M, Fauler M, Liss B, McLean PJ, Spada AR, ... ... Danzer KM, et al. Mutual exacerbation of peroxisome proliferator-activated receptor γ coactivator 1α deregulation and α-synuclein oligomerization. Annals of Neurology. 77: 15-32. PMID 25363075 DOI: 10.1002/ana.24294  0.64
2014 Lázaro DF, Rodrigues EF, Langohr R, Shahpasandzadeh H, Ribeiro T, Guerreiro P, Gerhardt E, Kröhnert K, Klucken J, Pereira MD, Popova B, Kruse N, Mollenhauer B, Rizzoli SO, Braus GH, ... Danzer KM, et al. Systematic comparison of the effects of alpha-synuclein mutations on its oligomerization and aggregation. Plos Genetics. 10: e1004741. PMID 25393002 DOI: 10.1371/journal.pgen.1004741  0.64
2014 Grozdanov V, Bliederhaeuser C, Ruf WP, Roth V, Fundel-Clemens K, Zondler L, Brenner D, Martin-Villalba A, Hengerer B, Kassubek J, Ludolph AC, Weishaupt JH, Danzer KM. Inflammatory dysregulation of blood monocytes in Parkinson’s disease patients Acta Neuropathologica. 128: 651-663. PMID 25284487 DOI: 10.1007/s00401-014-1345-4  0.64
2014 McFarland NR, Dimant H, Kibuuka L, Ebrahimi-Fakhari D, Desjardins CA, Danzer KM, Danzer M, Fan Z, Schwarzschild MA, Hirst W, McLean PJ. Chronic treatment with novel small molecule Hsp90 inhibitors rescues striatal dopamine levels but not α-synuclein-induced neuronal cell loss. Plos One. 9: e86048. PMID 24465863 DOI: 10.1371/journal.pone.0086048  0.64
2013 Eschbach J, Schwalenstöcker B, Soyal SM, Bayer H, Wiesner D, Akimoto C, Nilsson AC, Birve A, Meyer T, Dupuis L, Danzer KM, Andersen PM, Witting A, Ludolph AC, Patsch W, et al. PGC-1α is a male-specific disease modifier of human and experimental amyotrophic lateral sclerosis. Human Molecular Genetics. 22: 3477-84. PMID 23669350 DOI: 10.1093/hmg/ddt202  0.64
2012 Danzer KM, Kranich LR, Ruf WP, Cagsal-Getkin O, Winslow AR, Zhu L, Vanderburg CR, McLean PJ. Exosomal cell-to-cell transmission of alpha synuclein oligomers. Molecular Neurodegeneration. 7: 42. PMID 22920859 DOI: 10.1186/1750-1326-7-42  0.64
2011 Vlad C, Lindner K, Karreman C, Schildknecht S, Leist M, Tomczyk N, Rontree J, Langridge J, Danzer K, Ciossek T, Petre A, Gross ML, Hengerer B, Przybylski M. Autoproteolytic fragments are intermediates in the oligomerization/aggregation of the Parkinson's disease protein alpha-synuclein as revealed by ion mobility mass spectrometry. Chembiochem : a European Journal of Chemical Biology. 12: 2740-4. PMID 22162214 DOI: 10.1002/cbic.201100569  0.64
2011 Danzer KM, McLean PJ. Drug targets from genetics: α-synuclein. Cns & Neurological Disorders Drug Targets. 10: 712-23. PMID 21838671  0.64
2011 Welander H, Bontha SV, Näsström T, Karlsson M, Nikolajeff F, Danzer K, Kostka M, Kalimo H, Lannfelt L, Ingelsson M, Bergström J. Gelsolin co-occurs with Lewy bodies in vivo and accelerates α-synuclein aggregation in vitro. Biochemical and Biophysical Research Communications. 412: 32-8. PMID 21798243 DOI: 10.1016/j.bbrc.2011.07.027  0.64
2011 Hüls S, Högen T, Vassallo N, Danzer KM, Hengerer B, Giese A, Herms J. AMPA-receptor-mediated excitatory synaptic transmission is enhanced by iron-induced α-synuclein oligomers Journal of Neurochemistry. 117: 868-878. PMID 21426349 DOI: 10.1111/j.1471-4159.2011.07254.x  0.64
2011 Danzer KM, Ruf WP, Putcha P, Joyner D, Hashimoto T, Glabe C, Hyman BT, McLean PJ. Heat-shock protein 70 modulates toxic extracellular α-synuclein oligomers and rescues trans-synaptic toxicity. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 25: 326-36. PMID 20876215 DOI: 10.1096/fj.10-164624  0.64
2010 Putcha P, Danzer KM, Kranich LR, Scott A, Silinski M, Mabbett S, Hicks CD, Veal JM, Steed PM, Hyman BT, McLean PJ. Brain-permeable small-molecule inhibitors of Hsp90 prevent alpha-synuclein oligomer formation and rescue alpha-synuclein-induced toxicity. The Journal of Pharmacology and Experimental Therapeutics. 332: 849-57. PMID 19934398 DOI: 10.1124/jpet.109.158436  0.64
2008 Kostka M, Högen T, Danzer KM, Levin J, Habeck M, Wirth A, Wagner R, Glabe CG, Finger S, Heinzelmann U, Garidel P, Duan W, Ross CA, Kretzschmar H, Giese A. Single particle characterization of iron-induced pore-forming alpha-synuclein oligomers. The Journal of Biological Chemistry. 283: 10992-1003. PMID 18258594 DOI: 10.1074/jbc.M709634200  0.64
2007 Gillardon F, Rist W, Kussmaul L, Vogel J, Berg M, Danzer K, Kraut N, Hengerer B. Proteomic and functional alterations in brain mitochondria from Tg2576 mice occur before amyloid plaque deposition. Proteomics. 7: 605-16. PMID 17309106 DOI: 10.1002/pmic.200600728  0.64
Low-probability matches
2019 Kiechle M, von Einem B, Höfs L, Voehringer P, Grozdanov V, Markx D, Parlato R, Wiesner D, Mayer B, Sakk O, Baumann B, Lukassen S, Liss B, Ekici AB, Ludolph AC, ... ... Danzer KM, et al. In Vivo Protein Complementation Demonstrates Presynaptic α-Synuclein Oligomerization and Age-Dependent Accumulation of 8-16-mer Oligomer Species. Cell Reports. 29: 2862-2874.e9. PMID 31775051 DOI: 10.1016/j.celrep.2019.10.089  0.28
2019 Grozdanov V, Bousset L, Hoffmeister M, Bliederhaeuser C, Meier C, Madiona K, Pieri L, Kiechle M, McLean PJ, Kassubek J, Behrends C, Ludolph AC, Weishaupt JH, Melki R, Danzer KM. Increased immune activation by pathologic alpha-synuclein in Parkinson's Disease. Annals of Neurology. PMID 31343083 DOI: 10.1002/ana.25557  0.28
2017 von Einem B, Eschbach J, Kiechle M, Wahler A, Thal DR, McLean PJ, Weishaupt JH, Ludolph AC, von Arnim CAF, Danzer KM. The Golgi-localized, gamma ear-containing, ARF-binding (GGA) protein family alters alpha synuclein (α-syn) oligomerization and secretion. Aging. PMID 28722658 DOI: 10.18632/aging.101261  0.28
2017 Zondler L, Feiler MS, Freischmidt A, Ruf WP, Ludolph AC, Danzer KM, Weishaupt JH. Impaired activation of ALS monocytes by exosomes. Immunology and Cell Biology. 95: 207-214. PMID 27616750 DOI: 10.1038/icb.2016.89  0.28
2016 Bliederhaeuser C, Zondler L, Grozdanov V, Ruf WP, Brenner D, Melrose HL, Bauer P, Ludolph AC, Gillardon F, Kassubek J, Weishaupt JH, Danzer KM. LRRK2 contributes to monocyte dysregulation in Parkinson's disease. Acta Neuropathologica Communications. 4: 123. PMID 27884177 DOI: 10.1186/s40478-016-0396-2  0.28
2016 Helferich AM, McLean PJ, Weishaupt JH, Danzer KM. Commentary: alpha-synuclein interacts with SOD1 and promotes its oligomerization. Journal of Neurology & Neuromedicine. 1: 28-30. PMID 27853754  0.28
2016 Zondler L, Müller K, Khalaji S, Bliederhäuser C, Ruf WP, Grozdanov V, Thiemann M, Fundel-Clemes K, Freischmidt A, Holzmann K, Strobel B, Weydt P, Witting A, Thal DR, Helferich AM, ... ... Danzer KM, et al. Peripheral monocytes are functionally altered and invade the CNS in ALS patients. Acta Neuropathologica. PMID 26910103 DOI: 10.1007/s00401-016-1548-y  0.28
2007 Danzer KM, Haasen D, Karow AR, Moussaud S, Habeck M, Giese A, Kretzschmar H, Hengerer B, Kostka M. Different species of alpha-synuclein oligomers induce calcium influx and seeding. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 9220-32. PMID 17715357 DOI: 10.1523/JNEUROSCI.2617-07.2007  0.16
2019 Yilmaz R, Müller K, Brenner D, Volk AE, Borck G, Hermann A, Meitinger T, Strom TM, Danzer KM, Ludolph AC, Andersen PM, Weishaupt JH. SQSTM1/p62 variants in 486 patients with familial ALS from Germany and Sweden. Neurobiology of Aging. PMID 31859009 DOI: 10.1016/j.neurobiolaging.2019.10.018  0.08
2019 Brenner D, Rosenbohm A, Yilmaz R, Müller K, Grehl T, Petri S, Meyer T, Grosskreutz J, Weydt P, Ruf W, Neuwirth C, Weber M, Pinto S, Claeys KG, Schrank B, ... ... Danzer KM, et al. Reply: Adult-onset distal spinal muscular atrophy: a new phenotype associated with KIF5A mutations. Brain : a Journal of Neurology. PMID 31612906 DOI: 10.1093/brain/awz306  0.08
2019 Müller HP, Brenner D, Roselli F, Wiesner D, Abaei A, Gorges M, Danzer KM, Ludolph AC, Tsao W, Wong PC, Rasche V, Weishaupt JH, Kassubek J. Longitudinal diffusion tensor magnetic resonance imaging analysis at the cohort level reveals disturbed cortical and callosal microstructure with spared corticospinal tract in the ALS mouse model. Translational Neurodegeneration. 8: 27. PMID 31485326 DOI: 10.1186/s40035-019-0163-y  0.08
2019 Brenner D, Sieverding K, Bruno C, Lüningschrör P, Buck E, Mungwa S, Fischer L, Brockmann SJ, Ulmer J, Bliederhäuser C, Philibert CE, Satoh T, Akira S, Boillée S, Mayer B, ... ... Danzer KM, et al. Heterozygous loss has opposing effects in early and late stages of ALS in mice. The Journal of Experimental Medicine. PMID 30635357 DOI: 10.1084/jem.20180729  0.08
2018 Helferich AM, Brockmann SJ, Reinders J, Deshpande D, Holzmann K, Brenner D, Andersen PM, Petri S, Thal DR, Michaelis J, Otto M, Just S, Ludolph AC, Danzer KM, Freischmidt A, et al. Dysregulation of a novel miR-1825/TBCB/TUBA4A pathway in sporadic and familial ALS. Cellular and Molecular Life Sciences : Cmls. PMID 30030593 DOI: 10.1007/s00018-018-2873-1  0.08
2018 Grozdanov V, Danzer KM. Release and uptake of pathologic alpha-synuclein. Cell and Tissue Research. PMID 29411106 DOI: 10.1007/s00441-017-2775-9  0.08
2018 Brenner D, Yilmaz R, Müller K, Grehl T, Petri S, Meyer T, Grosskreutz J, Weydt P, Ruf W, Neuwirth C, Weber M, Pinto S, Claeys KG, Schrank B, Jordan B, ... ... Danzer KM, et al. Hot-spot KIF5A mutations cause familial ALS. Brain : a Journal of Neurology. PMID 29342275 DOI: 10.1093/brain/awx370  0.08
2018 Brockmann SJ, Freischmidt A, Oeckl P, Müller K, Ponna SK, Helferich AM, Paone C, Reinders J, Kojer K, Orth M, Jokela M, Auranen M, Udd B, Hermann A, Danzer KM, et al. CHCHD10 mutations p.R15L and p.G66V cause motoneuron disease by haploinsufficiency. Human Molecular Genetics. PMID 29315381 DOI: 10.1093/hmg/ddx436  0.08
2017 Zondler L, Kostka M, Garidel P, Heinzelmann U, Hengerer B, Mayer B, Weishaupt JH, Gillardon F, Danzer KM. Proteasome impairment by α-synuclein. Plos One. 12: e0184040. PMID 28945746 DOI: 10.1371/journal.pone.0184040  0.08
2016 Bayer H, Lang K, Barth E, Higelin J, Barteczko L, Pasquarelli N, Sprissler J, Lucas T, Holzmann K, Demestre M, Lindenberg KS, Danzer KM, Boeckers T, Ludolph AC, Dupuis L, et al. ALS-causing mutations differentially affect PGC-1α expression and function in the brain vs. peripheral tissues. Neurobiology of Disease. PMID 27818323 DOI: 10.1016/j.nbd.2016.11.001  0.08
2016 Koch Y, Helferich AM, Steinacker P, Oeckl P, Walther P, Weishaupt JH, Danzer KM, Otto M. Aggregated α-Synuclein Increases SOD1 Oligomerization in a Mouse Model of Amyotrophic Lateral Sclerosis. The American Journal of Pathology. 186: 2152-2161. PMID 27322773 DOI: 10.1016/j.ajpath.2016.04.008  0.08
2016 Linkus B, Wiesner D, Meßner M, Karabatsiakis A, Scheffold A, Rudolph KL, Thal DR, Weishaupt JH, Ludolph AC, Danzer KM. Telomere shortening leads to earlier age of onset in ALS mice. Aging. 8: 382-93. PMID 26978042 DOI: 10.18632/aging.100904  0.08
2014 Freischmidt A, Müller K, Zondler L, Weydt P, Volk AE, Božič AL, Walter M, Bonin M, Mayer B, von Arnim CA, Otto M, Dieterich C, Holzmann K, Andersen PM, Ludolph AC, ... Danzer KM, et al. Serum microRNAs in patients with genetic amyotrophic lateral sclerosis and pre-manifest mutation carriers. Brain : a Journal of Neurology. 137: 2938-50. PMID 25193138 DOI: 10.1093/brain/awu249  0.08
2014 Müller K, Andersen PM, Hübers A, Marroquin N, Volk AE, Danzer KM, Meitinger T, Ludolph AC, Strom TM, Weishaupt JH. Two novel mutations in conserved codons indicate that CHCHD10 is a gene associated with motor neuron disease. Brain : a Journal of Neurology. 137: e309. PMID 25113787 DOI: 10.1093/brain/awu227  0.08
2014 Eschbach J, Danzer KM. α-Synuclein in Parkinson's disease: pathogenic function and translation into animal models. Neuro-Degenerative Diseases. 14: 1-17. PMID 24080741 DOI: 10.1159/000354615  0.08
2017 Khalaji S, Zondler L, KleinJan F, Nolte U, Mulaw MA, Danzer KM, Weishaupt JH, Gottschalk KE. Age Increases Monocyte Adhesion on Collagen. Scientific Reports. 7: 46532. PMID 28513618 DOI: 10.1038/srep46532  0.01
2015 Wang P, Bohr W, Otto M, Danzer KM, Mizaikoff B. Quantifying amyloid fibrils in protein mixtures via infrared attenuated-total-reflection spectroscopy. Analytical and Bioanalytical Chemistry. 407: 4015-21. PMID 25869482 DOI: 10.1007/s00216-015-8623-4  0.01
2009 Danzer KM, Krebs SK, Wolff M, Birk G, Hengerer B. Seeding induced by alpha-synuclein oligomers provides evidence for spreading of alpha-synuclein pathology. Journal of Neurochemistry. 111: 192-203. PMID 19686384 DOI: 10.1111/j.1471-4159.2009.06324.x  0.01
2007 Danzer KM, Schnack C, Sutcliffe A, Hengerer B, Gillardon F. Functional protein kinase arrays reveal inhibition of p-21-activated kinase 4 by alpha-synuclein oligomers. Journal of Neurochemistry. 103: 2401-7. PMID 17883396 DOI: 10.1111/j.1471-4159.2007.04933.x  0.01
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