Karin Danzer - Publications

Affiliations: 
2008-2011 Neurology Massachusetts General Hospital, Boston, MA 

36/79 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Ruf WP, Palmer A, Dörfer L, Wiesner D, Buck E, Grozdanov V, Kassubek J, Dimou L, Ludolph AC, Huber-Lang M, Danzer KM. Thoracic trauma promotes alpha-Synuclein oligomerization in murine Parkinson's disease. Neurobiology of Disease. 105877. PMID 36162738 DOI: 10.1016/j.nbd.2022.105877  0.373
2022 Ruf WP, Meirelles JL, Danzer KM. Spreading of alpha-synuclein between different cell types. Behavioural Brain Research. 436: 114059. PMID 35995264 DOI: 10.1016/j.bbr.2022.114059  0.491
2021 Bhatia D, Grozdanov V, Ruf WP, Kassubek J, Ludolph AC, Weishaupt JH, Danzer KM. T-cell dysregulation is associated with disease severity in Parkinson's Disease. Journal of Neuroinflammation. 18: 250. PMID 34717679 DOI: 10.1186/s12974-021-02296-8  0.321
2020 Grozdanov V, Danzer KM. Intracellular Alpha-Synuclein and Immune Cell Function. Frontiers in Cell and Developmental Biology. 8: 562692. PMID 33178682 DOI: 10.3389/fcell.2020.562692  0.338
2020 Kiechle M, Grozdanov V, Danzer KM. The Role of Lipids in the Initiation of α-Synuclein Misfolding. Frontiers in Cell and Developmental Biology. 8: 562241. PMID 33042996 DOI: 10.3389/fcell.2020.562241  0.442
2019 Kiechle M, von Einem B, Höfs L, Voehringer P, Grozdanov V, Markx D, Parlato R, Wiesner D, Mayer B, Sakk O, Baumann B, Lukassen S, Liss B, Ekici AB, Ludolph AC, ... ... Danzer KM, et al. In Vivo Protein Complementation Demonstrates Presynaptic α-Synuclein Oligomerization and Age-Dependent Accumulation of 8-16-mer Oligomer Species. Cell Reports. 29: 2862-2874.e9. PMID 31775051 DOI: 10.1016/J.Celrep.2019.10.089  0.661
2019 Grozdanov V, Bousset L, Hoffmeister M, Bliederhaeuser C, Meier C, Madiona K, Pieri L, Kiechle M, McLean PJ, Kassubek J, Behrends C, Ludolph AC, Weishaupt JH, Melki R, Danzer KM. Increased immune activation by pathologic alpha-synuclein in Parkinson's Disease. Annals of Neurology. PMID 31343083 DOI: 10.1002/Ana.25557  0.65
2018 Grozdanov V, Danzer KM. Release and uptake of pathologic alpha-synuclein. Cell and Tissue Research. PMID 29411106 DOI: 10.1007/s00441-017-2775-9  0.526
2017 Zondler L, Kostka M, Garidel P, Heinzelmann U, Hengerer B, Mayer B, Weishaupt JH, Gillardon F, Danzer KM. Proteasome impairment by α-synuclein. Plos One. 12: e0184040. PMID 28945746 DOI: 10.1371/journal.pone.0184040  0.482
2017 von Einem B, Eschbach J, Kiechle M, Wahler A, Thal DR, McLean PJ, Weishaupt JH, Ludolph AC, von Arnim CAF, Danzer KM. The Golgi-localized, gamma ear-containing, ARF-binding (GGA) protein family alters alpha synuclein (α-syn) oligomerization and secretion. Aging. PMID 28722658 DOI: 10.18632/aging.101261  0.703
2017 Falkenburger B, Danzer K, Schneider A, Mollenhauer B. Recent developments in alpha-synuclein research – Clinical and preclinical data Basal Ganglia. 8: 22. DOI: 10.1016/J.Baga.2017.02.065  0.378
2016 Helferich AM, McLean PJ, Weishaupt JH, Danzer KM. Commentary: alpha-synuclein interacts with SOD1 and promotes its oligomerization. Journal of Neurology & Neuromedicine. 1: 28-30. PMID 27853754  0.67
2016 Koch Y, Helferich AM, Steinacker P, Oeckl P, Walther P, Weishaupt JH, Danzer KM, Otto M. Aggregated α-Synuclein Increases SOD1 Oligomerization in a Mouse Model of Amyotrophic Lateral Sclerosis. The American Journal of Pathology. 186: 2152-2161. PMID 27322773 DOI: 10.1016/j.ajpath.2016.04.008  0.401
2015 Stuendl A, Kunadt M, Kruse N, Bartels C, Moebius W, Danzer KM, Mollenhauer B, Schneider A. Induction of α-synuclein aggregate formation by CSF exosomes from patients with Parkinson's disease and dementia with Lewy bodies. Brain : a Journal of Neurology. PMID 26647156 DOI: 10.1093/brain/awv346  0.428
2015 Helferich AM, Ruf WP, Grozdanov V, Freischmidt A, Feiler MS, Zondler L, Ludolph AC, McLean PJ, Weishaupt JH, Danzer KM. α-synuclein interacts with SOD1 and promotes its oligomerization. Molecular Neurodegeneration. 10: 66. PMID 26643113 DOI: 10.1186/S13024-015-0062-3  0.677
2015 Bliederhaeuser C, Grozdanov V, Speidel A, Zondler L, Ruf WP, Bayer H, Kiechle M, Feiler MS, Freischmidt A, Brenner D, Witting A, Hengerer B, Fändrich M, Ludolph AC, Weishaupt JH, ... ... Danzer KM, et al. Age-dependent defects of alpha-synuclein oligomer uptake in microglia and monocytes. Acta Neuropathologica. PMID 26576561 DOI: 10.1007/s00401-015-1504-2  0.376
2015 von Einem B, Wahler A, Schips T, Serrano-Pozo A, Proepper C, Boeckers TM, Rueck A, Wirth T, Hyman BT, Danzer KM, Thal DR, von Arnim CA. The Golgi-Localized γ-Ear-Containing ARF-Binding (GGA) Proteins Alter Amyloid-β Precursor Protein (APP) Processing through Interaction of Their GAE Domain with the Beta-Site APP Cleaving Enzyme 1 (BACE1). Plos One. 10: e0129047. PMID 26053850 DOI: 10.1371/Journal.Pone.0129047  0.368
2015 Kunadt M, Eckermann K, Stuendl A, Gong J, Russo B, Strauss K, Rai S, Kügler S, Falomir Lockhart L, Schwalbe M, Krumova P, Oliveira LM, Bähr M, Möbius W, Levin J, ... ... Danzer KM, et al. Extracellular vesicle sorting of α-Synuclein is regulated by sumoylation. Acta Neuropathologica. 129: 695-713. PMID 25778619 DOI: 10.1007/S00401-015-1408-1  0.322
2015 Eschbach J, von Einem B, Müller K, Bayer H, Scheffold A, Morrison BE, Rudolph KL, Thal DR, Witting A, Weydt P, Otto M, Fauler M, Liss B, McLean PJ, Spada AR, ... ... Danzer KM, et al. Mutual exacerbation of peroxisome proliferator-activated receptor γ coactivator 1α deregulation and α-synuclein oligomerization. Annals of Neurology. 77: 15-32. PMID 25363075 DOI: 10.1002/Ana.24294  0.663
2014 Lázaro DF, Rodrigues EF, Langohr R, Shahpasandzadeh H, Ribeiro T, Guerreiro P, Gerhardt E, Kröhnert K, Klucken J, Pereira MD, Popova B, Kruse N, Mollenhauer B, Rizzoli SO, Braus GH, ... Danzer KM, et al. Systematic comparison of the effects of alpha-synuclein mutations on its oligomerization and aggregation. Plos Genetics. 10: e1004741. PMID 25393002 DOI: 10.1371/Journal.Pgen.1004741  0.476
2014 Grozdanov V, Bliederhaeuser C, Ruf WP, Roth V, Fundel-Clemens K, Zondler L, Brenner D, Martin-Villalba A, Hengerer B, Kassubek J, Ludolph AC, Weishaupt JH, Danzer KM. Inflammatory dysregulation of blood monocytes in Parkinson’s disease patients Acta Neuropathologica. 128: 651-663. PMID 25284487 DOI: 10.1007/s00401-014-1345-4  0.326
2014 McFarland NR, Dimant H, Kibuuka L, Ebrahimi-Fakhari D, Desjardins CA, Danzer KM, Danzer M, Fan Z, Schwarzschild MA, Hirst W, McLean PJ. Chronic treatment with novel small molecule Hsp90 inhibitors rescues striatal dopamine levels but not α-synuclein-induced neuronal cell loss. Plos One. 9: e86048. PMID 24465863 DOI: 10.1371/Journal.Pone.0086048  0.643
2014 Eschbach J, Danzer KM. α-Synuclein in Parkinson's disease: pathogenic function and translation into animal models. Neuro-Degenerative Diseases. 14: 1-17. PMID 24080741 DOI: 10.1159/000354615  0.44
2012 Danzer KM, Kranich LR, Ruf WP, Cagsal-Getkin O, Winslow AR, Zhu L, Vanderburg CR, McLean PJ. Exosomal cell-to-cell transmission of alpha synuclein oligomers. Molecular Neurodegeneration. 7: 42. PMID 22920859 DOI: 10.1186/1750-1326-7-42  0.733
2011 Vlad C, Lindner K, Karreman C, Schildknecht S, Leist M, Tomczyk N, Rontree J, Langridge J, Danzer K, Ciossek T, Petre A, Gross ML, Hengerer B, Przybylski M. Autoproteolytic fragments are intermediates in the oligomerization/aggregation of the Parkinson's disease protein alpha-synuclein as revealed by ion mobility mass spectrometry. Chembiochem : a European Journal of Chemical Biology. 12: 2740-4. PMID 22162214 DOI: 10.1002/Cbic.201100569  0.407
2011 Danzer KM, McLean PJ. Drug targets from genetics: α-synuclein. Cns & Neurological Disorders Drug Targets. 10: 712-23. PMID 21838671 DOI: 10.2174/187152711797247867  0.673
2011 Welander H, Bontha SV, Näsström T, Karlsson M, Nikolajeff F, Danzer K, Kostka M, Kalimo H, Lannfelt L, Ingelsson M, Bergström J. Gelsolin co-occurs with Lewy bodies in vivo and accelerates α-synuclein aggregation in vitro. Biochemical and Biophysical Research Communications. 412: 32-8. PMID 21798243 DOI: 10.1016/J.Bbrc.2011.07.027  0.559
2011 Danzer KM, Ruf WP, Putcha P, Joyner D, Hashimoto T, Glabe C, Hyman BT, McLean PJ. Heat-shock protein 70 modulates toxic extracellular α-synuclein oligomers and rescues trans-synaptic toxicity. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 25: 326-36. PMID 20876215 DOI: 10.1096/Fj.10-164624  0.705
2011 Vlad C, Lindner K, Karreman C, Schildknecht S, Leist M, Tomczyk N, Rontree J, Langridge J, Danzer K, Ciossek T, Petre A, Gross ML, Hengerer B, Przybylski M. Inside Cover: Autoproteolytic Fragments Are Intermediates in the Oligomerization/Aggregation of the Parkinson's Disease Protein Alpha-Synuclein as Revealed by Ion Mobility Mass Spectrometry (ChemBioChem 18/2011) Chembiochem. 12: 2706-2706. DOI: 10.1002/Cbic.201190086  0.456
2010 Putcha P, Danzer KM, Kranich LR, Scott A, Silinski M, Mabbett S, Hicks CD, Veal JM, Steed PM, Hyman BT, McLean PJ. Brain-permeable small-molecule inhibitors of Hsp90 prevent alpha-synuclein oligomer formation and rescue alpha-synuclein-induced toxicity. The Journal of Pharmacology and Experimental Therapeutics. 332: 849-57. PMID 19934398 DOI: 10.1124/Jpet.109.158436  0.714
2009 Danzer KM, Krebs SK, Wolff M, Birk G, Hengerer B. Seeding induced by alpha-synuclein oligomers provides evidence for spreading of alpha-synuclein pathology. Journal of Neurochemistry. 111: 192-203. PMID 19686384 DOI: 10.1111/j.1471-4159.2009.06324.x  0.471
2009 Hüls S, Högen T, Danzer K, Hengerer B, Vassallo N, Kretzschmar H, Giese A, Herms J. P4-222: Alpha-synuclein oligomers alter excitatory synaptic transmission via both pre- and postsynaptic mechanisms Alzheimer's & Dementia. 5: P495-P495. DOI: 10.1016/J.Jalz.2009.04.688  0.343
2008 Schnack C, Danzer KM, Hengerer B, Gillardon F. Protein array analysis of oligomerization-induced changes in alpha-synuclein protein-protein interactions points to an interference with Cdc42 effector proteins. Neuroscience. 154: 1450-7. PMID 18541383 DOI: 10.1016/j.neuroscience.2008.02.049  0.368
2008 Kostka M, Högen T, Danzer KM, Levin J, Habeck M, Wirth A, Wagner R, Glabe CG, Finger S, Heinzelmann U, Garidel P, Duan W, Ross CA, Kretzschmar H, Giese A. Single particle characterization of iron-induced pore-forming alpha-synuclein oligomers. The Journal of Biological Chemistry. 283: 10992-1003. PMID 18258594 DOI: 10.1074/Jbc.M709634200  0.418
2007 Danzer KM, Schnack C, Sutcliffe A, Hengerer B, Gillardon F. Functional protein kinase arrays reveal inhibition of p-21-activated kinase 4 by alpha-synuclein oligomers. Journal of Neurochemistry. 103: 2401-7. PMID 17883396 DOI: 10.1111/j.1471-4159.2007.04933.x  0.382
2007 Danzer KM, Haasen D, Karow AR, Moussaud S, Habeck M, Giese A, Kretzschmar H, Hengerer B, Kostka M. Different species of alpha-synuclein oligomers induce calcium influx and seeding. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 9220-32. PMID 17715357 DOI: 10.1523/JNEUROSCI.2617-07.2007  0.75
Low-probability matches (unlikely to be authored by this person)
2007 Gillardon F, Rist W, Kussmaul L, Vogel J, Berg M, Danzer K, Kraut N, Hengerer B. Proteomic and functional alterations in brain mitochondria from Tg2576 mice occur before amyloid plaque deposition. Proteomics. 7: 605-16. PMID 17309106 DOI: 10.1002/Pmic.200600728  0.299
2016 Bliederhaeuser C, Zondler L, Grozdanov V, Ruf WP, Brenner D, Melrose HL, Bauer P, Ludolph AC, Gillardon F, Kassubek J, Weishaupt JH, Danzer KM. LRRK2 contributes to monocyte dysregulation in Parkinson's disease. Acta Neuropathologica Communications. 4: 123. PMID 27884177 DOI: 10.1186/s40478-016-0396-2  0.295
2020 Kiechle M, Grozdanov V, Danzer KM. The Role of Lipids in the Initiation of α-Synuclein Misfolding Frontiers in Cell and Developmental Biology. 8. DOI: 10.3389/fcell.2020.562241  0.279
2020 Rahman AA, Soto-Avellaneda A, Yong Jin H, Stojkovska I, Lai NK, Albright JE, Webb AR, Oe E, Valarde JP, Oxford AE, Urquhart PE, Wagner B, Brown C, Amado I, Vasquez P, ... ... Danzer KM, et al. Enhanced hyaluronan signaling and autophagy dysfunction by VPS35 D620N. Neuroscience. PMID 32540366 DOI: 10.1016/j.neuroscience.2020.06.009  0.272
2013 Eschbach J, Schwalenstöcker B, Soyal SM, Bayer H, Wiesner D, Akimoto C, Nilsson AC, Birve A, Meyer T, Dupuis L, Danzer KM, Andersen PM, Witting A, Ludolph AC, Patsch W, et al. PGC-1α is a male-specific disease modifier of human and experimental amyotrophic lateral sclerosis. Human Molecular Genetics. 22: 3477-84. PMID 23669350 DOI: 10.1093/hmg/ddt202  0.257
2015 Feiler MS, Strobel B, Freischmidt A, Helferich AM, Kappel J, Brewer BM, Li D, Thal DR, Walther P, Ludolph AC, Danzer KM, Weishaupt JH. TDP-43 is intercellularly transmitted across axon terminals. The Journal of Cell Biology. 211: 897-911. PMID 26598621 DOI: 10.1083/Jcb.201504057  0.245
2016 Bayer H, Lang K, Barth E, Higelin J, Barteczko L, Pasquarelli N, Sprissler J, Lucas T, Holzmann K, Demestre M, Lindenberg KS, Danzer KM, Boeckers T, Ludolph AC, Dupuis L, et al. ALS-causing mutations differentially affect PGC-1α expression and function in the brain vs. peripheral tissues. Neurobiology of Disease. PMID 27818323 DOI: 10.1016/J.Nbd.2016.11.001  0.228
2011 Hüls S, Högen T, Vassallo N, Danzer KM, Hengerer B, Giese A, Herms J. AMPA-receptor-mediated excitatory synaptic transmission is enhanced by iron-induced α-synuclein oligomers Journal of Neurochemistry. 117: 868-878. PMID 21426349 DOI: 10.1111/J.1471-4159.2011.07254.X  0.206
2018 Helferich AM, Brockmann SJ, Reinders J, Deshpande D, Holzmann K, Brenner D, Andersen PM, Petri S, Thal DR, Michaelis J, Otto M, Just S, Ludolph AC, Danzer KM, Freischmidt A, et al. Dysregulation of a novel miR-1825/TBCB/TUBA4A pathway in sporadic and familial ALS. Cellular and Molecular Life Sciences : Cmls. PMID 30030593 DOI: 10.1007/s00018-018-2873-1  0.202
2014 Zondler L, Müller K, Grozdanov V, Bliederhäuser C, Weydt P, Ludolph AC, Danzer K, Weishaupt JH. Monocyte subtypes in ALS Journal of Neuroimmunology. 275: 94. DOI: 10.1016/J.Jneuroim.2014.08.252  0.2
2021 Ruf WP, Freischmidt A, Grozdanov V, Roth V, Brockmann SJ, Mollenhauer B, Martin D, Haslinger B, Fundel-Clemens K, Otto M, Arnim CV, Holzmann K, Ludolph AC, Weishaupt JH, Danzer KM. Protein Binding Partners of Dysregulated miRNAs in Parkinson's Disease Serum. Cells. 10. PMID 33918274 DOI: 10.3390/cells10040791  0.182
2015 Wang P, Bohr W, Otto M, Danzer KM, Mizaikoff B. Quantifying amyloid fibrils in protein mixtures via infrared attenuated-total-reflection spectroscopy. Analytical and Bioanalytical Chemistry. 407: 4015-21. PMID 25869482 DOI: 10.1007/S00216-015-8623-4  0.171
2020 Sieverding K, Ulmer J, Bruno C, Satoh T, Tsao W, Freischmidt A, Akira S, Wong PC, Ludolph AC, Danzer KM, Lobsiger CS, Brenner D, Weishaupt JH. Hemizygous deletion of Tbk1 worsens neuromuscular junction pathology in TDP-43 transgenic mice. Experimental Neurology. 113496. PMID 33038415 DOI: 10.1016/j.expneurol.2020.113496  0.16
2019 Brenner D, Sieverding K, Bruno C, Lüningschrör P, Buck E, Mungwa S, Fischer L, Brockmann SJ, Ulmer J, Bliederhäuser C, Philibert CE, Satoh T, Akira S, Boillée S, Mayer B, ... ... Danzer KM, et al. Heterozygous loss has opposing effects in early and late stages of ALS in mice. The Journal of Experimental Medicine. PMID 30635357 DOI: 10.1084/Jem.20180729  0.158
2014 Freischmidt A, Müller K, Zondler L, Weydt P, Volk AE, Božič AL, Walter M, Bonin M, Mayer B, von Arnim CA, Otto M, Dieterich C, Holzmann K, Andersen PM, Ludolph AC, ... Danzer KM, et al. Serum microRNAs in patients with genetic amyotrophic lateral sclerosis and pre-manifest mutation carriers. Brain : a Journal of Neurology. 137: 2938-50. PMID 25193138 DOI: 10.1093/brain/awu249  0.157
2021 Freischmidt A, Goswami A, Limm K, Zimyanin VL, Demestre M, Glaß H, Holzmann K, Helferich AM, Brockmann SJ, Tripathi P, Yamoah A, Poser I, Oefner PJ, Böckers TM, Aronica E, ... ... Danzer KM, et al. A serum microRNA sequence reveals fragile X protein pathology in amyotrophic lateral sclerosis. Brain : a Journal of Neurology. PMID 33871026 DOI: 10.1093/brain/awab018  0.155
2023 Yazar V, Kühlwein JK, Knehr A, Grozdanov V, Ekici AB, Ludolph AC, Danzer KM. Impaired ATF3 signaling involves SNAP25 in SOD1 mutant ALS patients. Scientific Reports. 13: 12019. PMID 37491426 DOI: 10.1038/s41598-023-38684-8  0.15
2016 Zondler L, Müller K, Khalaji S, Bliederhäuser C, Ruf WP, Grozdanov V, Thiemann M, Fundel-Clemes K, Freischmidt A, Holzmann K, Strobel B, Weydt P, Witting A, Thal DR, Helferich AM, ... ... Danzer KM, et al. Peripheral monocytes are functionally altered and invade the CNS in ALS patients Acta Neuropathologica. 1-21. DOI: 10.1007/s00401-016-1548-y  0.148
2017 Zondler L, Feiler MS, Freischmidt A, Ruf WP, Ludolph AC, Danzer KM, Weishaupt JH. Impaired activation of ALS monocytes by exosomes. Immunology and Cell Biology. 95: 207-214. PMID 27616750 DOI: 10.1038/icb.2016.89  0.147
2016 Zondler L, Müller K, Khalaji S, Bliederhäuser C, Ruf WP, Grozdanov V, Thiemann M, Fundel-Clemes K, Freischmidt A, Holzmann K, Strobel B, Weydt P, Witting A, Thal DR, Helferich AM, ... ... Danzer KM, et al. Peripheral monocytes are functionally altered and invade the CNS in ALS patients. Acta Neuropathologica. PMID 26910103 DOI: 10.1007/s00401-016-1548-y  0.146
2023 Kühlwein JK, Ruf WP, Kandler K, Witzel S, Lang C, Mulaw MA, Ekici AB, Weishaupt JH, Ludolph AC, Grozdanov V, Danzer KM. ALS is imprinted in the chromatin accessibility of blood cells. Cellular and Molecular Life Sciences : Cmls. 80: 131. PMID 37095391 DOI: 10.1007/s00018-023-04769-w  0.137
2014 Wahler A, Schnack C, von Einem B, Danzer KM, von Arnim CA. P1-059: ENGULFMENT ADAPTER PTB DOMAIN CONTAINING 1 (GULP1) FORMS DIMERS IN VIVO, AND DIMERIZATION IS FURTHER PROMOTED BY AMYLOID PRECURSOR PROTEIN (APP) Alzheimer's & Dementia. 10: P324-P325. DOI: 10.1016/j.jalz.2014.05.295  0.136
2019 Yilmaz R, Müller K, Brenner D, Volk AE, Borck G, Hermann A, Meitinger T, Strom TM, Danzer KM, Ludolph AC, Andersen PM, Weishaupt JH. SQSTM1/p62 variants in 486 patients with familial ALS from Germany and Sweden. Neurobiology of Aging. PMID 31859009 DOI: 10.1016/j.neurobiolaging.2019.10.018  0.135
2016 Linkus B, Wiesner D, Meßner M, Karabatsiakis A, Scheffold A, Rudolph KL, Thal DR, Weishaupt JH, Ludolph AC, Danzer KM. Telomere shortening leads to earlier age of onset in ALS mice. Aging. 8: 382-93. PMID 26978042 DOI: 10.18632/aging.100904  0.132
2022 Ruf WP, Hannon E, Freischmidt A, Grozdanov V, Brenner D, Müller K, Knehr A, Günther K, Dorst J, Ammerpohl O, Danzer KM, Mill J, Ludolph AC, Weishaupt JH. Methylome analysis of ALS patients and presymptomatic mutation carriers in blood cells. Neurobiology of Aging. 116: 16-24. PMID 35537341 DOI: 10.1016/j.neurobiolaging.2022.04.003  0.132
2015 Freischmidt A, Wieland T, Richter B, Ruf W, Schaeffer V, Müller K, Marroquin N, Nordin F, Hübers A, Weydt P, Pinto S, Press R, Millecamps S, Molko N, Bernard E, ... ... Danzer KM, et al. Haploinsufficiency of TBK1 causes familial ALS and fronto-temporal dementia. Nature Neuroscience. 18: 631-6. PMID 25803835 DOI: 10.1038/Nn.4000  0.131
2014 Müller K, Andersen PM, Hübers A, Marroquin N, Volk AE, Danzer KM, Meitinger T, Ludolph AC, Strom TM, Weishaupt JH. Two novel mutations in conserved codons indicate that CHCHD10 is a gene associated with motor neuron disease. Brain : a Journal of Neurology. 137: e309. PMID 25113787 DOI: 10.1093/brain/awu227  0.127
2022 Streit L, Kuhn T, Vomhof T, Bopp V, Ludolph AC, Weishaupt JH, Gebhardt JCM, Michaelis J, Danzer KM. Stress induced TDP-43 mobility loss independent of stress granules. Nature Communications. 13: 5480. PMID 36123343 DOI: 10.1038/s41467-022-32939-0  0.125
2023 Ramachandran S, Grozdanov V, Leins B, Kandler K, Witzel S, Mulaw M, Ludolph AC, Weishaupt JH, Danzer KM. Low T-cell reactivity to TDP-43 peptides in ALS. Frontiers in Immunology. 14: 1193507. PMID 37545536 DOI: 10.3389/fimmu.2023.1193507  0.123
2023 Yazar V, Ruf WP, Knehr A, Günther K, Ammerpohl O, Danzer KM, Ludolph AC. DNA Methylation Analysis in Monozygotic Twins Discordant for ALS in Blood Cells. Epigenetics Insights. 16: 25168657231172159. PMID 37152709 DOI: 10.1177/25168657231172159  0.113
2018 Brenner D, Yilmaz R, Müller K, Grehl T, Petri S, Meyer T, Grosskreutz J, Weydt P, Ruf W, Neuwirth C, Weber M, Pinto S, Claeys KG, Schrank B, Jordan B, ... ... Danzer KM, et al. Hot-spot KIF5A mutations cause familial ALS. Brain : a Journal of Neurology. PMID 29342275 DOI: 10.1093/Brain/Awx370  0.11
2020 Bruno C, Sieverding K, Freischmidt A, Satoh T, Walther P, Mayer B, Ludolph AC, Akira S, Yilmazer-Hanke D, Danzer KM, Lobsiger CS, Brenner D, Weishaupt JH. Haploinsufficiency of TANK-binding kinase 1 prepones age-associated neuroinflammatory changes without causing motor neuron degeneration in aged mice. Brain Communications. 2: fcaa133. PMID 33005894 DOI: 10.1093/braincomms/fcaa133  0.109
2018 Brockmann SJ, Freischmidt A, Oeckl P, Müller K, Ponna SK, Helferich AM, Paone C, Reinders J, Kojer K, Orth M, Jokela M, Auranen M, Udd B, Hermann A, Danzer KM, et al. CHCHD10 mutations p.R15L and p.G66V cause motoneuron disease by haploinsufficiency. Human Molecular Genetics. PMID 29315381 DOI: 10.1093/hmg/ddx436  0.105
2017 Khalaji S, Zondler L, KleinJan F, Nolte U, Mulaw MA, Danzer KM, Weishaupt JH, Gottschalk KE. Age Increases Monocyte Adhesion on Collagen. Scientific Reports. 7: 46532. PMID 28513618 DOI: 10.1038/srep46532  0.089
2023 Brockmann SJ, Buck E, Casoli T, Meirelles JL, Ruf WP, Fabbietti P, Holzmann K, Weishaupt JH, Ludolph AC, Conti F, Danzer KM. Mitochondrial genome study in blood of maternally inherited ALS cases. Human Genomics. 17: 70. PMID 37507754 DOI: 10.1186/s40246-023-00516-1  0.086
2019 Müller HP, Brenner D, Roselli F, Wiesner D, Abaei A, Gorges M, Danzer KM, Ludolph AC, Tsao W, Wong PC, Rasche V, Weishaupt JH, Kassubek J. Longitudinal diffusion tensor magnetic resonance imaging analysis at the cohort level reveals disturbed cortical and callosal microstructure with spared corticospinal tract in the ALS mouse model. Translational Neurodegeneration. 8: 27. PMID 31485326 DOI: 10.1186/S40035-019-0163-Y  0.077
2020 Michel D, Danzer KM, Groß R, Conzelmann C, Müller JA, Freischmidt A, Weishaupt JH, Heller S, Münch J, Michel M, Stamminger T, Kleger A, Otto M. Rapid, convenient and efficient kit-independent detection of SARS-CoV-2 RNA. Journal of Virological Methods. 113965. PMID 32891677 DOI: 10.1016/j.jviromet.2020.113965  0.074
2015 Freischmidt A, Müller K, Zondler L, Weydt P, Mayer B, von Arnim CA, Hübers A, Dorst J, Otto M, Holzmann K, Ludolph AC, Danzer KM, Weishaupt JH. Serum microRNAs in sporadic amyotrophic lateral sclerosis. Neurobiology of Aging. 36: 2660.e15-20. PMID 26142125 DOI: 10.1016/j.neurobiolaging.2015.06.003  0.071
2016 Brenner D, Müller K, Wieland T, Weydt P, Böhm S, Lulé D, Hübers A, Neuwirth C, Weber M, Borck G, Wahlqvist M, Danzer KM, Volk AE, Meitinger T, Strom TM, et al. NEK1 mutations in familial amyotrophic lateral sclerosis. Brain : a Journal of Neurology. 139: e28. PMID 26945885 DOI: 10.1093/brain/aww033  0.069
2015 Marroquin N, Stranz S, Müller K, Wieland T, Ruf WP, Brockmann SJ, Danzer KM, Borck G, Hübers A, Weydt P, Meitinger T, Strom TM, Rosenbohm A, Ludolph AC, Weishaupt JH. Screening for CHCHD10 mutations in a large cohort of sporadic ALS patients: no evidence for pathogenicity of the p.P34S variant. Brain : a Journal of Neurology. PMID 26362909 DOI: 10.1093/brain/awv218  0.062
2022 Buck E, Oeckl P, Grozdanov V, Bopp V, Kühlwein JK, Ruf WP, Wiesner D, Roselli F, Weishaupt JH, Ludolph AC, Otto M, Danzer KM. Increased NF-L levels in the TDP-43 ALS mouse model resemble NF-L levels in ALS patients. Acta Neuropathologica. 144: 161-164. PMID 35585288 DOI: 10.1007/s00401-022-02436-1  0.06
2022 Gómez de San José N, Goossens J, Al Shweiki MR, Halbgebauer S, Oeckl P, Steinacker P, Danzer KM, Graf H, Schönfeldt-Lecuona C, Belbin O, Lleó A, Vanmechelen E, Otto M. Glutamate receptor 4 as a fluid biomarker for the diagnosis of psychiatric disorders. Journal of Psychiatric Research. 156: 390-397. PMID 36323141 DOI: 10.1016/j.jpsychires.2022.10.010  0.046
2019 Brenner D, Rosenbohm A, Yilmaz R, Müller K, Grehl T, Petri S, Meyer T, Grosskreutz J, Weydt P, Ruf W, Neuwirth C, Weber M, Pinto S, Claeys KG, Schrank B, ... ... Danzer KM, et al. Reply: Adult-onset distal spinal muscular atrophy: a new phenotype associated with KIF5A mutations. Brain : a Journal of Neurology. PMID 31612906 DOI: 10.1093/brain/awz306  0.043
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