Ronald Martinus Alexander Heeren - Publications

Affiliations: 
FOM Institute AMOLF, Amsterdam, Noord-Holland, Netherlands 
 2002-2012 Chemistry Utrecht University, Utrecht, Netherlands 
 2014- Maastricht University, Maastricht, Limburg, Netherlands 
Area:
biomolecular massspectrometry
Website:
https://www.maastrichtuniversity.nl/r.heeren

136 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Hese LV, Vaysse P, Siegel TP, Heeren R, Rex S, Cuypers E. Real-time drug detection using a diathermic knife combined to rapid evaporative ionisation mass spectrometry Talanta. 221: 121391. PMID 33076053 DOI: 10.1016/J.Talanta.2020.121391  0.347
2019 Barré F, Rocha B, Dewez F, Towers M, Murray P, Claude E, Cillero-Pastor B, Heeren R, Siegel TP. Faster raster matrix-assisted laser desorption/ionization mass spectrometry imaging of lipids at high lateral resolution International Journal of Mass Spectrometry. 437: 38-48. DOI: 10.1016/J.Ijms.2018.09.015  0.501
2019 Lu C, Goossens P, Karel J, Gijbels M, Smirnov E, Balluff B, Heeren R, Biessen E. Towards The Complete Picture: Computational Strategies To Identify Ms-Imaging Derived Molecular Fingerprints Associated With Inflammatory Cell Phenotypes Atherosclerosis. 287. DOI: 10.1016/J.Atherosclerosis.2019.06.227  0.366
2018 Flinders B, Huizing L, van Heerden M, Cuyckens F, Olde Damink S, Heeren R, Schaap F, Vreeken R. Cross-species molecular imaging of bile salts and lipids: Identification of hydroxyl-sulfatides as marker of bile ducts Journal of Hepatology. 68: S462. DOI: 10.1016/S0168-8278(18)31169-3  0.318
2017 Balluff B, Hanselmann M, Heeren RM. Mass Spectrometry Imaging for the Investigation of Intratumor Heterogeneity. Advances in Cancer Research. 134: 201-230. PMID 28110651 DOI: 10.1016/Bs.Acr.2016.11.008  0.37
2017 Eveque-Mourroux M, Emans P, Welting T, Boonen A, Heeren R, Cillero-Pastor B. Matrix Assisted Laser Desorption Ionization Imaging Mass Spectrometry Applied To Human Osteoarthritis Cartilage Annals of the Rheumatic Diseases. 76: 977-977. DOI: 10.1136/Annrheumdis-2017-Eular.6498  0.415
2016 Barré FP, Flinders B, Garcia JP, Jansen I, Huizing LR, Porta T, Creemers LB, Heeren RM, Cillero-Pastor B. Derivatization Strategies for the Detection of Triamcinolone Acetonide in Cartilage by Using Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Imaging. Analytical Chemistry. 88: 12051-12059. PMID 28193015 DOI: 10.1021/Acs.Analchem.6B02491  0.389
2016 Scott AJ, Flinders B, Cappell J, Liang T, Pelc RS, Tran B, Kilgour DP, Heeren RM, Goodlett DR, Ernst RK. Norharmane Matrix Enhances Detection of Endotoxin by MALDI-MS for Simultaneous Profiling of Pathogen, Host, and Vector Systems. Pathogens and Disease. PMID 27650574 DOI: 10.1093/Femspd/Ftw097  0.32
2016 van den Akker CC, Schleeger M, Bruinen AL, Deckert-Gaudig T, Velikov KP, Heeren RM, Deckert V, Bonn M, Koenderink GH. Multimodal Spectroscopic Study of Amyloid Fibril Polymorphism. The Journal of Physical Chemistry. B. PMID 27487391 DOI: 10.1021/Acs.Jpcb.6B05339  0.448
2016 Fisher GL, Bruinen AL, Ogrinc Potočnik N, Hammond JS, Bryan SR, Larson PE, Heeren RM. A New Method and Mass Spectrometer Design for TOF-SIMS Parallel Imaging MS/MS. Analytical Chemistry. PMID 27181574 DOI: 10.1021/Acs.Analchem.6B01022  0.514
2016 Cassese A, Ellis SR, Ogrinc Potočnik N, Burgermeister E, Ebert M, Walch A, van den Maagdenberg AM, McDonnell LA, Heeren RM, Balluff B. Spatial Autocorrelation in Mass Spectrometry Imaging. Analytical Chemistry. PMID 27180608 DOI: 10.1021/Acs.Analchem.6B00672  0.416
2016 Ellis SR, Cappell J, Potočnik NO, Balluff B, Hamaide J, Van der Linden A, Heeren RM. More from less: high-throughput dual polarity lipid imaging of biological tissues. The Analyst. 141: 3832-41. PMID 27041214 DOI: 10.1039/C6An00169F  0.407
2016 Škrášková K, Claude E, Jones EA, Towers M, Ellis SR, Heeren RM. Enhanced capabilities for imaging gangliosides in murine brain with matrix-assisted laser desorption/ionization and desorption electrospray ionization mass spectrometry coupled to ion mobility separation. Methods (San Diego, Calif.). PMID 26922843 DOI: 10.1016/J.Ymeth.2016.02.014  0.528
2016 Mascini NE, Cheng M, Jiang L, Rizwan A, Podmore H, Bhandari D, Römpp A, Glunde K, Heeren RM. Mass Spectrometry Imaging of the Hypoxia Marker Pimonidazole in a Breast Tumor Model. Analytical Chemistry. PMID 26891127 DOI: 10.1021/Acs.Analchem.5B04032  0.377
2016 Cuypers E, Flinders B, Boone CM, Bosman IJ, Lusthof KJ, van Asten AC, Tytgat J, Heeren RM. A closer look into the consequences of decontamination procedures in forensic hair analysis using MetA-SIMS analysis. Analytical Chemistry. PMID 26878081 DOI: 10.1021/Acs.Analchem.5B03979  0.337
2016 Hommersom B, Syed SU, Eijkel GB, Kilgour DP, Goodlett DR, Heeren RM. An ambient detection system for visualization of charged particles generated with ionization methods at atmospheric pressure. Rapid Communications in Mass Spectrometry : Rcm. 30: 352-8. PMID 26754127 DOI: 10.1002/Rcm.7442  0.312
2016 Jjunju FP, Maher S, Damon DE, Barrett RM, Syed SU, Heeren RM, Taylor S, Badu-Tawiah AK. Screening and Quantification of Aliphatic Primary Alkyl Corrosion Inhibitor Amines in Water Samples by Paper Spray Mass Spectrometry. Analytical Chemistry. PMID 26727190 DOI: 10.1021/Acs.Analchem.5B03992  0.309
2016 Bruinen AL, van Oevelen C, Eijkel GB, Van Heerden M, Cuyckens F, Heeren RM. Mass Spectrometry Imaging of Drug Related Crystal-Like Structures in Formalin-Fixed Frozen and Paraffin-Embedded Rabbit Kidney Tissue Sections. Journal of the American Society For Mass Spectrometry. 27: 117-23. PMID 26384683 DOI: 10.1007/S13361-015-1254-3  0.417
2015 Ogrinc Potočnik N, Porta T, Becker M, Heeren RM, Ellis SR. Use of advantageous, volatile matrices enabled by next-generation high-speed matrix-assisted laser desorption/ionization time-of-flight imaging employing a scanning laser beam. Rapid Communications in Mass Spectrometry : Rcm. 29: 2195-203. PMID 26522310 DOI: 10.1002/Rcm.7379  0.467
2015 Jjunju FP, Maher S, Li A, Syed SU, Smith B, Heeren RM, Taylor S, Cooks RG. Hand-Held Portable Desorption Atmospheric Pressure Chemical Ionization Ion Source for in Situ Analysis of Nitroaromatic Explosives. Analytical Chemistry. PMID 26329926 DOI: 10.1021/Acs.Analchem.5B02684  0.394
2015 Jiang L, Chughtai K, Purvine SO, Bhujwalla ZM, Raman V, Paša-Tolić L, Heeren RM, Glunde K. MALDI-Mass Spectrometric Imaging Revealing Hypoxia-Driven Lipids and Proteins in a Breast Tumor Model. Analytical Chemistry. 87: 5947-56. PMID 25993305 DOI: 10.1021/Ac504503X  0.302
2015 Flinders B, Cuypers E, Zeijlemaker H, Tytgat J, Heeren RM. Preparation of longitudinal sections of hair samples for the analysis of cocaine by MALDI-MS/MS and TOF-SIMS imaging. Drug Testing and Analysis. 7: 859-65. PMID 25981643 DOI: 10.1002/Dta.1812  0.439
2015 Škrášková K, Khmelinskii A, Abdelmoula WM, De Munter S, Baes M, McDonnell L, Dijkstra J, Heeren RM. Precise Anatomic Localization of Accumulated Lipids in Mfp2 Deficient Murine Brains Through Automated Registration of SIMS Images to the Allen Brain Atlas. Journal of the American Society For Mass Spectrometry. 26: 948-57. PMID 25916600 DOI: 10.1007/S13361-015-1146-6  0.409
2015 Georgi N, Cillero-Pastor B, Eijkel GB, Periyasamy PC, Kiss A, van Blitterswijk C, Post JN, Heeren RM, Karperien M. Differentiation of mesenchymal stem cells under hypoxia and normoxia: lipid profiles revealed by time-of-flight secondary ion mass spectrometry and multivariate analysis. Analytical Chemistry. 87: 3981-8. PMID 25742117 DOI: 10.1021/Acs.Analchem.5B00114  0.377
2015 Syed SU, Maher S, Eijkel GB, Ellis SR, Jjunju F, Taylor S, Heeren RM. Direct ion imaging approach for investigation of ion dynamics in multipole ion guides. Analytical Chemistry. 87: 3714-20. PMID 25710191 DOI: 10.1021/Ac5041764  0.418
2015 Römpp A, Both JP, Brunelle A, Heeren RM, Laprévote O, Prideaux B, Seyer A, Spengler B, Stoeckli M, Smith DF. Mass spectrometry imaging of biological tissue: an approach for multicenter studies. Analytical and Bioanalytical Chemistry. 407: 2329-35. PMID 25575583 DOI: 10.1007/S00216-014-8410-7  0.457
2015 Mascini NE, Eijkel GB, ter Brugge P, Jonkers J, Wesseling J, Heeren RM. The use of mass spectrometry imaging to predict treatment response of patient-derived xenograft models of triple-negative breast cancer. Journal of Proteome Research. 14: 1069-75. PMID 25553735 DOI: 10.1021/Pr501067Z  0.355
2015 Cillero-Pastor B, Eijkel GB, Blanco FJ, Heeren RM. Protein classification and distribution in osteoarthritic human synovial tissue by matrix-assisted laser desorption ionization mass spectrometry imaging. Analytical and Bioanalytical Chemistry. 407: 2213-22. PMID 25504090 DOI: 10.1007/S00216-014-8342-2  0.398
2015 Rocha B, Cillero-Pastor B, Eijkel G, Bruinen AL, Ruiz-Romero C, Heeren RM, Blanco FJ. Characterization of lipidic markers of chondrogenic differentiation using mass spectrometry imaging. Proteomics. 15: 702-13. PMID 25346268 DOI: 10.1002/Pmic.201400260  0.387
2015 Smith DF, Schulz C, Konijnenburg M, Kilic M, Heeren RM. Distributed computing strategies for processing of FT-ICR MS imaging datasets for continuous mode data visualization. Analytical and Bioanalytical Chemistry. 407: 2321-7. PMID 25273594 DOI: 10.1007/S00216-014-8210-0  0.364
2015 Syed SU, Eijkel GB, Maher S, Kistemaker P, Taylor S, Heeren RM. A micropixelated ion-imaging detector for mass resolution enhancement of a QMS instrument. Analytical and Bioanalytical Chemistry. 407: 2055-62. PMID 25270865 DOI: 10.1007/S00216-014-8158-0  0.512
2014 Robbe MF, Both JP, Prideaux B, Klinkert I, Picaud V, Schramm T, Hester A, Guevara V, Stoeckli M, Roempp A, Heeren RM, Spengler B, Gal O, Haan S. Corrigendum to "Software tools of the Computis European project to process mass spectrometry images an experimental and theoretical study" [Eur. J. Mass Spectrom. 20(5), 351-360 (2014)]. European Journal of Mass Spectrometry (Chichester, England). 20: 487. PMID 25905873 DOI: 10.1255/ejms.1315  0.323
2014 Robbe MF, Both JP, Prideaux B, Klinkert I, Picaud V, Schramm T, Hester A, Guevara V, Stoeckli M, Roempp A, Heeren RM, Spengler B, Gala O, Haan S. Software tools of the Computis European project to process mass spectrometry images. European Journal of Mass Spectrometry (Chichester, England). 20: 351-60. PMID 25707124 DOI: 10.1255/Ejms.1293  0.439
2014 Seaman C, Flinders B, Eijkel G, Heeren RM, Bricklebank N, Clench MR. "Afterlife experiment": use of MALDI-MS and SIMS imaging for the study of the nitrogen cycle within plants. Analytical Chemistry. 86: 10071-7. PMID 25230319 DOI: 10.1021/Ac501191W  0.37
2014 Abdelmoula WM, Škrášková K, Balluff B, Carreira RJ, Tolner EA, Lelieveldt BP, van der Maaten L, Morreau H, van den Maagdenberg AM, Heeren RM, McDonnell LA, Dijkstra J. Automatic generic registration of mass spectrometry imaging data to histology using nonlinear stochastic embedding. Analytical Chemistry. 86: 9204-11. PMID 25133861 DOI: 10.1021/Ac502170F  0.505
2014 Syed SU, Eijkel GB, Kistemaker P, Ellis S, Maher S, Smith DF, Heeren RM. Experimental investigation of the 2D ion beam profile generated by an ESI octopole-QMS system. Journal of the American Society For Mass Spectrometry. 25: 1780-7. PMID 25113629 DOI: 10.1007/S13361-014-0958-0  0.437
2014 Cuypers E, Flinders B, Bosman IJ, Lusthof KJ, Van Asten AC, Tytgat J, Heeren RM. Hydrogen peroxide reactions on cocaine in hair using imaging mass spectrometry. Forensic Science International. 242: 103-10. PMID 25047217 DOI: 10.1016/J.Forsciint.2014.06.035  0.351
2014 Ogrinc Potočnik N, Škrášková K, Flinders B, Pelicon P, Heeren RM. Gold sputtered fiducial markers for combined secondary ion mass spectrometry and MALDI imaging of tissue samples. Analytical Chemistry. 86: 6781-5. PMID 24918500 DOI: 10.1021/Ac500308S  0.54
2014 DeBord JD, Smith DF, Anderton CR, Heeren RM, Paša-Toli? L, Gomer RH, Fernandez-Lima FA. Secondary ion mass spectrometry imaging of Dictyostelium discoideum aggregation streams. Plos One. 9: e99319. PMID 24911189 DOI: 10.1371/Journal.Pone.0099319  0.522
2014 Peffers MJ, Cillero-Pastor B, Eijkel GB, Clegg PD, Heeren RM. Matrix assisted laser desorption ionization mass spectrometry imaging identifies markers of ageing and osteoarthritic cartilage. Arthritis Research & Therapy. 16: R110. PMID 24886698 DOI: 10.1186/Ar4560  0.392
2014 Ellis SR, Soltwisch J, Heeren RM. Time-resolved imaging of the MALDI linear-TOF ion cloud: direct visualization and exploitation of ion optical phenomena using a position- and time-sensitive detector. Journal of the American Society For Mass Spectrometry. 25: 809-19. PMID 24658803 DOI: 10.1007/S13361-014-0839-6  0.451
2014 Kiss A, Smith DF, Reschke BR, Powell MJ, Heeren RM. Top-down mass spectrometry imaging of intact proteins by laser ablation ESI FT-ICR MS. Proteomics. 14: 1283-9. PMID 24375984 DOI: 10.1002/Pmic.201300306  0.511
2014 Soltwisch J, Göritz G, Jungmann JH, Kiss A, Smith DF, Ellis SR, Heeren RM. MALDI mass spectrometry imaging in microscope mode with infrared lasers: bypassing the diffraction limits. Analytical Chemistry. 86: 321-5. PMID 24308447 DOI: 10.1021/Ac403421V  0.521
2014 Ellis SR, Bruinen AL, Heeren RM. A critical evaluation of the current state-of-the-art in quantitative imaging mass spectrometry. Analytical and Bioanalytical Chemistry. 406: 1275-89. PMID 24281323 DOI: 10.1007/S00216-013-7478-9  0.436
2014 Mashaghi A, Mashaghi S, Reviakine I, Heeren RM, Sandoghdar V, Bonn M. Label-free characterization of biomembranes: from structure to dynamics. Chemical Society Reviews. 43: 887-900. PMID 24253187 DOI: 10.1039/C3Cs60243E  0.437
2014 Cillero-Pastor B, Heeren RM. Matrix-assisted laser desorption ionization mass spectrometry imaging for peptide and protein analyses: a critical review of on-tissue digestion. Journal of Proteome Research. 13: 325-35. PMID 24087847 DOI: 10.1021/Pr400743A  0.435
2013 Škrášková K, Heeren RM. A review of complementary separation methods and matrix assisted laser desorption ionization-mass spectrometry imaging: lowering sample complexity. Journal of Chromatography. A. 1319: 1-13. PMID 24377103 DOI: 10.1016/J.Chroma.2013.10.027  0.498
2013 Kiss A, Smith DF, Jungmann JH, Heeren RM. Cluster secondary ion mass spectrometry microscope mode mass spectrometry imaging. Rapid Communications in Mass Spectrometry : Rcm. 27: 2745-50. PMID 24214859 DOI: 10.1002/Rcm.6719  0.509
2013 Stutts WL, Menger RF, Kiss A, Heeren RM, Yost RA. Characterization of phosphatidylcholine oxidation products by MALDI MS(n). Analytical Chemistry. 85: 11410-9. PMID 24180376 DOI: 10.1021/Ac402400F  0.419
2013 Smith DF, Kilgour DP, Konijnenburg M, O'Connor PB, Heeren RM. Absorption mode FTICR mass spectrometry imaging. Analytical Chemistry. 85: 11180-4. PMID 24175640 DOI: 10.1021/Ac403039T  0.64
2013 Gerber F, Marty F, Eijkel GB, Basler K, Brunner E, Furrer R, Heeren RM. Multiorder correction algorithms to remove image distortions from mass spectrometry imaging data sets. Analytical Chemistry. 85: 10249-54. PMID 24093946 DOI: 10.1021/Ac402018E  0.423
2013 Ellis SR, Jungmann JH, Smith DF, Soltwisch J, Heeren RM. Enhanced detection of high-mass proteins by using an active pixel detector. Angewandte Chemie (International Ed. in English). 52: 11261-4. PMID 24039122 DOI: 10.1002/Anie.201305501  0.433
2013 Smith DF, Kiss A, Leach FE, Robinson EW, Paša-Tolić L, Heeren RM. High mass accuracy and high mass resolving power FT-ICR secondary ion mass spectrometry for biological tissue imaging. Analytical and Bioanalytical Chemistry. 405: 6069-76. PMID 23685962 DOI: 10.1007/S00216-013-7048-1  0.438
2013 Jungmann JH, Mascini NE, Kiss A, Smith DF, Klinkert I, Eijkel GB, Duursma MC, Cillero Pastor B, Chughtai K, Chughtai S, Heeren RM. A MASSive laboratory tour. An interactive mass spectrometry outreach activity for children. Journal of the American Society For Mass Spectrometry. 24: 979-82. PMID 23681852 DOI: 10.1007/S13361-013-0663-4  0.365
2013 Kiss A, Jungmann JH, Smith DF, Heeren RM. Microscope mode secondary ion mass spectrometry imaging with a Timepix detector. The Review of Scientific Instruments. 84: 013704. PMID 23387656 DOI: 10.1063/1.4772396  0.476
2013 Wehrl HF, Schwab J, Hasenbach K, Reischl G, Tabatabai G, Quintanilla-Martinez L, Jiru F, Chughtai K, Kiss A, Cay F, Bukala D, Heeren RM, Pichler BJ, Sauter AW. Multimodal elucidation of choline metabolism in a murine glioma model using magnetic resonance spectroscopy and 11C-choline positron emission tomography. Cancer Research. 73: 1470-80. PMID 23345160 DOI: 10.1158/0008-5472.Can-12-2532  0.301
2013 Cillero-Pastor B, Eijkel GB, Kiss A, Blanco FJ, Heeren RM. Matrix-assisted laser desorption ionization-imaging mass spectrometry: a new methodology to study human osteoarthritic cartilage. Arthritis and Rheumatism. 65: 710-20. PMID 23280504 DOI: 10.1002/Art.37799  0.481
2013 Jungmann JH, Heeren RM. Detection systems for mass spectrometry imaging: a perspective on novel developments with a focus on active pixel detectors. Rapid Communications in Mass Spectrometry : Rcm. 27: 1-23. PMID 23239313 DOI: 10.1002/Rcm.6418  0.43
2013 Pirman DA, Reich RF, Kiss A, Heeren RM, Yost RA. Quantitative MALDI tandem mass spectrometric imaging of cocaine from brain tissue with a deuterated internal standard. Analytical Chemistry. 85: 1081-9. PMID 23214490 DOI: 10.1021/Ac302960J  0.461
2013 Pirman DA, Kiss A, Heeren RM, Yost RA. Identifying tissue-specific signal variation in MALDI mass spectrometric imaging by use of an internal standard. Analytical Chemistry. 85: 1090-6. PMID 23214468 DOI: 10.1021/Ac3029618  0.45
2013 Chughtai K, Jiang L, Post H, Winnard PT, Greenwood TR, Raman V, Bhujwalla ZM, Heeren RM, Glunde K. Mass spectrometric imaging of red fluorescent protein in breast tumor xenografts. Journal of the American Society For Mass Spectrometry. 24: 711-7. PMID 23184411 DOI: 10.1007/S13361-012-0503-Y  0.392
2013 Hanselmann M, Röder J, Köthe U, Renard BY, Heeren RM, Hamprecht FA. Active learning for convenient annotation and classification of secondary ion mass spectrometry images. Analytical Chemistry. 85: 147-55. PMID 23157438 DOI: 10.1021/Ac3023313  0.427
2013 Jiang L, Greenwood TR, van Hove ER, Chughtai K, Raman V, Winnard PT, Heeren RM, Artemov D, Glunde K. Combined MR, fluorescence and histology imaging strategy in a human breast tumor xenograft model. Nmr in Biomedicine. 26: 285-98. PMID 22945331 DOI: 10.1002/Nbm.2846  0.33
2013 Chughtai K, Jiang L, Greenwood TR, Glunde K, Heeren RM. Mass spectrometry images acylcarnitines, phosphatidylcholines, and sphingomyelin in MDA-MB-231 breast tumor models. Journal of Lipid Research. 54: 333-44. PMID 22930811 DOI: 10.1194/Jlr.M027961  0.369
2013 Jiang L, Chughtai K, Greenwood T, Eijkel G, Heeren R, Glunde K. Abstract 2668: Revealing protein biomarkers in breast tumor models by combining MRSI and MSI. Cancer Research. 73: 2668-2668. DOI: 10.1158/1538-7445.Am2013-2668  0.356
2012 Fornai L, Angelini A, Klinkert I, Giskes F, Kiss A, Eijkel G, Amstalden-van Hove EA, Klerk LA, Fedrigo M, Pieraccini G, Moneti G, Valente M, Thiene G, Heeren RM. Three-dimensional molecular reconstruction of rat heart with mass spectrometry imaging. Analytical and Bioanalytical Chemistry. 404: 2927-38. PMID 23064671 DOI: 10.1007/S00216-012-6451-3  0.384
2012 Cillero-Pastor B, Eijkel G, Kiss A, Blanco FJ, Heeren RM. Time-of-flight secondary ion mass spectrometry-based molecular distribution distinguishing healthy and osteoarthritic human cartilage. Analytical Chemistry. 84: 8909-16. PMID 22950553 DOI: 10.1021/Ac301853Q  0.394
2012 Smith DF, Kharchenko A, Konijnenburg M, Klinkert I, Paša-Tolić L, Heeren RM. Advanced mass calibration and visualization for FT-ICR mass spectrometry imaging. Journal of the American Society For Mass Spectrometry. 23: 1865-72. PMID 22926971 DOI: 10.1007/S13361-012-0464-1  0.449
2012 Jungmann JH, Smith DF, MacAleese L, Klinkert I, Visser J, Heeren RM. Biological tissue imaging with a position and time sensitive pixelated detector. Journal of the American Society For Mass Spectrometry. 23: 1679-88. PMID 22836864 DOI: 10.1007/S13361-012-0444-5  0.516
2012 Jungmann JH, Heeren RM. Emerging technologies in mass spectrometry imaging. Journal of Proteomics. 75: 5077-92. PMID 22469858 DOI: 10.1016/J.Jprot.2012.03.022  0.46
2012 Kharchenko A, Vladimirov G, Heeren RM, Nikolaev EN. Performance of Orbitrap mass analyzer at various space charge and non-ideal field conditions: simulation approach. Journal of the American Society For Mass Spectrometry. 23: 977-87. PMID 22354683 DOI: 10.1007/S13361-011-0325-3  0.372
2012 Chughtai K, Jiang L, Greenwood TR, Klinkert I, Amstalden van Hove ER, Heeren RM, Glunde K. Fiducial markers for combined 3-dimensional mass spectrometric and optical tissue imaging. Analytical Chemistry. 84: 1817-23. PMID 22283706 DOI: 10.1021/Ac203373H  0.422
2012 Bult W, de Leeuw H, Steinebach OM, van der Bom MJ, Wolterbeek HT, Heeren RM, Bakker CJ, van Het Schip AD, Hennink WE, Nijsen JF. Radioactive holmium acetylacetonate microspheres for interstitial microbrachytherapy: an in vitro and in vivo stability study. Pharmaceutical Research. 29: 827-36. PMID 22068276 DOI: 10.1007/S11095-011-0610-7  0.327
2012 Vladimirov G, Hendrickson CL, Blakney GT, Marshall AG, Heeren RM, Nikolaev EN. Fourier transform ion cyclotron resonance mass resolution and dynamic range limits calculated by computer modeling of ion cloud motion. Journal of the American Society For Mass Spectrometry. 23: 375-84. PMID 22033889 DOI: 10.1007/S13361-011-0268-8  0.421
2011 Smith DF, Robinson EW, Tolmachev AV, Heeren RM, Paša-Tolić L. C60 secondary ion Fourier transform ion cyclotron resonance mass spectrometry. Analytical Chemistry. 83: 9552-6. PMID 22060180 DOI: 10.1021/Ac2023348  0.421
2011 van Hove ER, Smith DF, Fornai L, Glunde K, Heeren RM. An alternative paper based tissue washing method for mass spectrometry imaging: localized washing and fragile tissue analysis. Journal of the American Society For Mass Spectrometry. 22: 1885-90. PMID 21952901 DOI: 10.1007/S13361-011-0203-Z  0.436
2011 Svara FN, Kiss A, Jaskolla TW, Karas M, Heeren RM. High-reactivity matrices increase the sensitivity of matrix enhanced secondary ion mass spectrometry. Analytical Chemistry. 83: 8308-13. PMID 21939214 DOI: 10.1021/Ac202222H  0.459
2011 Nasioudis A, van Velde JW, Heeren RM, van den Brink OF. Detailed molecular characterization of castor oil ethoxylates by liquid chromatography multistage mass spectrometry. Journal of Chromatography. A. 1218: 7166-72. PMID 21890139 DOI: 10.1016/J.Chroma.2011.08.032  0.449
2011 Jungmann JH, MacAleese L, Visser J, Vrakking MJ, Heeren RM. High dynamic range bio-molecular ion microscopy with the Timepix detector. Analytical Chemistry. 83: 7888-94. PMID 21882854 DOI: 10.1021/Ac2017629  0.517
2011 Aizikov K, Smith DF, Chargin DA, Ivanov S, Lin TY, Heeren RM, O'Connor PB. Vacuum compatible sample positioning device for matrix assisted laser desorption∕ionization Fourier transform ion cyclotron resonance mass spectrometry imaging. The Review of Scientific Instruments. 82: 054102. PMID 21639522 DOI: 10.1063/1.3594099  0.791
2011 Smith DF, Aizikov K, Duursma MC, Giskes F, Spaanderman DJ, McDonnell LA, O'Connor PB, Heeren RM. An external matrix-assisted laser desorption ionization source for flexible FT-ICR Mass spectrometry imaging with internal calibration on adjacent samples. Journal of the American Society For Mass Spectrometry. 22: 130-7. PMID 21472551 DOI: 10.1007/S13361-010-0003-X  0.799
2011 MacAleese L, Duursma MC, Klerk LA, Fisher G, Heeren RM. Protein identification with Liquid Chromatography and Matrix Enhanced Secondary Ion Mass Spectrometry (LC-ME-SIMS). Journal of Proteomics. 74: 993-1001. PMID 21333768 DOI: 10.1016/J.Jprot.2011.02.009  0.464
2011 Kiss A, Heeren RM. Size, weight and position: ion mobility spectrometry and imaging MS combined. Analytical and Bioanalytical Chemistry. 399: 2623-34. PMID 21225246 DOI: 10.1007/S00216-010-4644-1  0.486
2011 Rago G, Marty F, Day J, Heeren R, Basler K, Brunner E, Bonn M. Label-Free 3D Imaging of Development of Cell Patterns in Drosophila melanogaster Wing Imaginal Disc Microscopy and Microanalysis. 17: 228-229. DOI: 10.1017/S1431927611002017  0.469
2011 Cillero-Pastor B, Eijkel G, Kiss A, Blanco F, Heeren R. 57 Identification And Different Localization Of Proteins In The Superficial And The Deep Human Oa Cartilage By Imaging Mass Spectrometry Osteoarthritis and Cartilage. 19. DOI: 10.1016/S1063-4584(11)60084-8  0.432
2010 Amstalden van Hove ER, Blackwell TR, Klinkert I, Eijkel GB, Heeren RM, Glunde K. Multimodal mass spectrometric imaging of small molecules reveals distinct spatio-molecular signatures in differentially metastatic breast tumor models. Cancer Research. 70: 9012-21. PMID 21045154 DOI: 10.1158/0008-5472.Can-10-0360  0.309
2010 Jungmann JH, Gijsbertsen A, Visser J, Visschers J, Heeren RM, Vrakking MJ. A new imaging method for understanding chemical dynamics: efficient slice imaging using an in-vacuum pixel detector. The Review of Scientific Instruments. 81: 103112. PMID 21034080 DOI: 10.1063/1.3489890  0.377
2010 Jungmann JH, MacAleese L, Buijs R, Giskes F, de Snaijer A, Visser J, Visschers J, Vrakking MJ, Heeren RM. Fast, high resolution mass spectrometry imaging using a Medipix pixelated detector. Journal of the American Society For Mass Spectrometry. 21: 2023-30. PMID 20971654 DOI: 10.1016/J.Jasms.2010.08.014  0.504
2010 Nasioudis A, Memboeuf A, Heeren RM, Smith DF, Vékey K, Drahos L, van den Brink OF. Discrimination of polymers by using their characteristic collision energy in tandem mass spectrometry. Analytical Chemistry. 82: 9350-6. PMID 20961067 DOI: 10.1021/Ac101936V  0.354
2010 Klerk LA, Dankers PY, Popa ER, Bosman AW, Sanders ME, Reedquist KA, Heeren RM. TOF-secondary ion mass spectrometry imaging of polymeric scaffolds with surrounding tissue after in vivo implantation. Analytical Chemistry. 82: 4337-43. PMID 20462187 DOI: 10.1021/Ac100837N  0.361
2010 Chughtai K, Heeren RM. Mass spectrometric imaging for biomedical tissue analysis. Chemical Reviews. 110: 3237-77. PMID 20423155 DOI: 10.1021/Cr100012C  0.492
2010 Amstalden van Hove ER, Smith DF, Heeren RM. A concise review of mass spectrometry imaging. Journal of Chromatography. A. 1217: 3946-54. PMID 20223463 DOI: 10.1016/J.Chroma.2010.01.033  0.526
2010 Froesch M, Luxembourg SL, Verheijde D, Heeren RM. Imaging mass spectrometry using a delay-line detector. European Journal of Mass Spectrometry (Chichester, England). 16: 35-45. PMID 20065513 DOI: 10.1255/Ejms.1052  0.511
2010 Klerk LA, Lockyer NP, Kharchenko A, MacAleese L, Dankers PY, Vickerman JC, Heeren RM. C60+ secondary ion microscopy using a delay line detector. Analytical Chemistry. 82: 801-7. PMID 20043656 DOI: 10.1021/Ac902587G  0.426
2010 Barbu IM, Smith DF, van Breukelen B, van der Burgt YE, Duursma MC, Heck AJ, Heeren RM, Krijgsveld J. On-the-fly targeted selection of labeled peptides in liquid chromatography/mass spectrometry based quantitative proteomics. Rapid Communications in Mass Spectrometry : Rcm. 24: 239-41. PMID 20013948 DOI: 10.1002/Rcm.4385  0.362
2010 Stauber J, MacAleese L, Franck J, Claude E, Snel M, Kaletas BK, Wiel IM, Wisztorski M, Fournier I, Heeren RM. On-tissue protein identification and imaging by MALDI-ion mobility mass spectrometry. Journal of the American Society For Mass Spectrometry. 21: 338-47. PMID 19926301 DOI: 10.1016/J.Jasms.2009.09.016  0.502
2010 Leach FE, Kharchenko A, Heeren RM, Nikolaev E, Amster IJ. Comparison of particle-in-cell simulations with experimentally observed frequency shifts between ions of the same mass-to-charge in Fourier transform ion cyclotron resonance mass spectrometry. Journal of the American Society For Mass Spectrometry. 21: 203-8. PMID 19896390 DOI: 10.1016/J.Jasms.2009.10.001  0.407
2009 KaletaÅŸ BK, van der Wiel IM, Stauber J, Güzel C, Kros JM, Luider TM, Heeren RM. Sample preparation issues for tissue imaging by imaging MS. Proteomics. 9: 2622-33. PMID 19415667 DOI: 10.1002/Pmic.200800364  0.461
2009 Heeren RM, Smith DF, Stauber J, Kükrer-Kaletas B, MacAleese L. Imaging mass spectrometry: hype or hope? Journal of the American Society For Mass Spectrometry. 20: 1006-14. PMID 19318278 DOI: 10.1016/J.Jasms.2009.01.011  0.468
2009 Altelaar AF, Heeren RM. Tissue analysis with high-resolution imaging mass spectrometry. Methods in Molecular Biology (Clifton, N.J.). 492: 295-308. PMID 19241041 DOI: 10.1007/978-1-59745-493-3_18  0.481
2009 MacAleese L, Stauber J, Heeren RM. Perspectives for imaging mass spectrometry in the proteomics landscape. Proteomics. 9: 819-34. PMID 19212956 DOI: 10.1002/Pmic.200800363  0.439
2009 van der Burgt YE, Palmblad M, Dalebout H, Heeren RM, Deelder AM. Electron capture dissociation of peptide hormone changes upon opening of the tocin ring and complexation with transition metal cations. Rapid Communications in Mass Spectrometry : Rcm. 23: 31-8. PMID 19051230 DOI: 10.1002/Rcm.3849  0.331
2008 Geels RB, Calmat S, Heck AJ, van der Vies SM, Heeren RM. Thermal activation of the co-chaperonins GroES and gp31 probed by mass spectrometry. Rapid Communications in Mass Spectrometry : Rcm. 22: 3633-41. PMID 18972453 DOI: 10.1002/Rcm.3782  0.387
2008 Taban IM, van der Burgt YE, Duursma M, Takáts Z, Seynen M, Konijnenburg M, Vijftigschild A, Attema I, Heeren RM. A novel workflow control system for Fourier transform ion cyclotron resonance mass spectrometry allows for unique on-the-fly data-dependent decisions. Rapid Communications in Mass Spectrometry : Rcm. 22: 1245-56. PMID 18383214 DOI: 10.1002/Rcm.3440  0.478
2007 Nikolaev EN, Heeren RM, Popov AM, Pozdneev AV, Chingin KS. Realistic modeling of ion cloud motion in a Fourier transform ion cyclotron resonance cell by use of a particle-in-cell approach. Rapid Communications in Mass Spectrometry : Rcm. 21: 3527-46. PMID 17944004 DOI: 10.1002/Rcm.3234  0.378
2007 McDonnell LA, Heeren RM. Imaging mass spectrometry. Mass Spectrometry Reviews. 26: 606-43. PMID 17471576 DOI: 10.1002/Mas.20124  0.536
2007 Mihalca R, van der Burgt YE, Heck AJ, Heeren RM. Disulfide bond cleavages observed in SORI-CID of three nonapeptides complexed with divalent transition-metal cations. Journal of Mass Spectrometry : Jms. 42: 450-8. PMID 17295413 DOI: 10.1002/Jms.1175  0.425
2007 van der Burgt YE, Taban IM, Konijnenburg M, Biskup M, Duursma MC, Heeren RM, Römpp A, van Nieuwpoort RV, Bal HE. Parallel processing of large datasets from NanoLC-FTICR-MS measurements. Journal of the American Society For Mass Spectrometry. 18: 152-61. PMID 17055738 DOI: 10.1016/J.Jasms.2006.09.005  0.379
2007 Geels RB, van der Vies SM, Heck AJ, Heeren RM. Comparative gas-phase activation of two similar non-covalent heptameric protein complexes: gp31 and GroES International Journal of Mass Spectrometry. 265: 159-168. DOI: 10.1016/J.Ijms.2007.02.008  0.341
2006 Luxembourg SL, Vaezaddeh AR, Amstalden ER, Zimmermann-Ivol CG, Hochstrasser DF, Heeren RM. The molecular scanner in microscope mode. Rapid Communications in Mass Spectrometry : Rcm. 20: 3435-42. PMID 17066367 DOI: 10.1002/Rcm.2747  0.497
2006 Geels RB, van der Vies SM, Heck AJ, Heeren RM. Electron capture dissociation as structural probe for noncovalent gas-phase protein assemblies. Analytical Chemistry. 78: 7191-6. PMID 17037920 DOI: 10.1021/Ac060960P  0.309
2006 Altelaar AF, Klinkert I, Jalink K, de Lange RP, Adan RA, Heeren RM, Piersma SR. Gold-enhanced biomolecular surface imaging of cells and tissue by SIMS and MALDI mass spectrometry. Analytical Chemistry. 78: 734-42. PMID 16448046 DOI: 10.1021/Ac0513111  0.488
2006 Kleinnijenhuis AJ, Mihalca R, Heeren RM, Heck AJ. Atypical behavior in the electron capture induced dissociation of biologically relevant transition metal ion complexes of the peptide hormone oxytocin International Journal of Mass Spectrometry. 253: 217-224. DOI: 10.1016/J.Ijms.2006.03.005  0.317
2005 Heeren RM. Proteome imaging: a closer look at life's organization. Proteomics. 5: 4316-26. PMID 16252308 DOI: 10.1002/Pmic.200500406  0.376
2005 Kleinnijenhuis AJ, Heck AJ, Duursma MC, Heeren RM. Does double electron capture lead to the formation of biradicals? An ECD-SORI-CID study on lacticin 481. Journal of the American Society For Mass Spectrometry. 16: 1595-601. PMID 16099166 DOI: 10.1016/J.Jasms.2005.05.010  0.359
2005 van Duijn E, Bakkes PJ, Heeren RM, van den Heuvel RH, van Heerikhuizen H, van der Vies SM, Heck AJ. Monitoring macromolecular complexes involved in the chaperonin-assisted protein folding cycle by mass spectrometry. Nature Methods. 2: 371-6. PMID 15846365 DOI: 10.1038/Nmeth753  0.401
2005 Altelaar AF, van Minnen J, Jiménez CR, Heeren RM, Piersma SR. Direct molecular imaging of Lymnaea stagnalis nervous tissue at subcellular spatial resolution by mass spectrometry. Analytical Chemistry. 77: 735-41. PMID 15679338 DOI: 10.1021/ac048329g  0.419
2004 Heeren RM, Kleinnijenhuis AJ, McDonnell LA, Mize TH. A mini-review of mass spectrometry using high-performance FTICR-MS methods. Analytical and Bioanalytical Chemistry. 378: 1048-58. PMID 14716471 DOI: 10.1007/S00216-003-2446-4  0.467
2004 van der Weerd J, Heeren RM, Boon JJ. Preparation Methods and Accessories for the Infrared Spectroscopic Analysis of Multi-Layer Paint Films Studies in Conservation. 49: 193-210. DOI: 10.1179/Sic.2004.49.3.193  0.512
2003 McDonnell LA, Mize TH, Luxembourg SL, Koster S, Eijkel GB, Verpoorte E, de Rooij NF, Heeren RM. Using matrix peaks to map topography: increased mass resolution and enhanced sensitivity in chemical imaging. Analytical Chemistry. 75: 4373-81. PMID 14632039 DOI: 10.1021/Ac034401J  0.505
2003 Kleinnijenhuis AJ, Duursma MC, Breukink E, Heeren RM, Heck AJ. Localization of intramolecular monosulfide bridges in lantibiotics determined with electron capture induced dissociation. Analytical Chemistry. 75: 3219-25. PMID 12964772 DOI: 10.1021/Ac0263770  0.345
2003 Guo X, Duursma MC, Kistemaker PG, Nibbering NM, Vekey K, Drahos L, Heeren RM. Manipulating internal energy of protonated biomolecules in electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry. Journal of Mass Spectrometry : Jms. 38: 597-606. PMID 12827629 DOI: 10.1002/Jms.480  0.372
2003 Koster S, Duursma MC, Boon JJ, Heeren RM, Ingemann S, van Benthem RA, de Koster CG. Electron capture and collisionally activated dissociation mass spectrometry of doubly charged hyperbranched polyesteramides. Journal of the American Society For Mass Spectrometry. 14: 332-41. PMID 12686480 DOI: 10.1016/S1044-0305(03)00004-7  0.543
2003 van der Weerd J, van Veen MK, Heeren RM, Boon JJ. Identification of pigments in paint cross sections by reflection visible light imaging microspectroscopy. Analytical Chemistry. 75: 716-22. PMID 12622357 DOI: 10.1021/Ac020282G  0.553
2002 Castillejo M, Martin M, Oujia M, Silva D, Torres R, Manousaki A, Zafiropulos V, van den Brink OF, Heeren RM, Teule R, Silva A, Gouveia H. Analytical study of the chemical and physical changes induced by KrF laser cleaning of tempera paints. Analytical Chemistry. 74: 4662-71. PMID 12349968 DOI: 10.1021/Ac025778C  0.366
2002 Koster S, Duursma MC, Guo X, van Benthem RA, de Koster CG, Boon JJ, Heeren RM. Isomer separation of hyperbranched polyesteramides with gas-phase H/D exchange and a novel MS(n) approach: DoDIP. Journal of Mass Spectrometry : Jms. 37: 792-802. PMID 12203673 DOI: 10.1002/Jms.336  0.552
2002 van Rooij G, Boon J, Duursma M, Heeren R. Probing mass discriminations and mass shifts in the ITMS mass spectra of externally generated MALDI ions with synthetic polymers International Journal of Mass Spectrometry. 221: 191-207. DOI: 10.1016/S1387-3806(02)00989-2  0.655
2001 van den Brink OF, Boon JJ, O'Connor PB, Duursma MC, Heeren RM. Matrix-assisted laser desorption/ionization Fourier transform mass spectrometric analysis of oxygenated triglycerides and phosphatidylcholines in egg tempera paint dosimeters used for environmental monitoring of museum display conditions. Journal of Mass Spectrometry : Jms. 36: 479-92. PMID 11391804 DOI: 10.1002/Jms.145  0.665
2001 Bento M, Pereira H, Cunha M, Moutinho A, Berg Kvd, Boon JJ, Brink Ovd, Heeren R. Fragmentation of Suberin and Composition of Aliphatic Monomers Released by Methanolysis of Cork from Quercus suber L.,Analysed by GC-MS, SEC and MALDI-MS Holzforschung. 55: 487-493. DOI: 10.1515/Hf.2001.080  0.536
2000 Koster S, Duursma MC, Boon JJ, Nielen MW, de Koster CG, Heeren RM. Current awareness Journal of Mass Spectrometry : Jms. 35: 750-9. PMID 10862128 DOI: 10.1002/1096-9888(200006)35:6<750::AID-JMS979>3.0.CO;2-9  0.502
2000 Koster S, Duursma MC, Boon JJ, Nielen MW, de Koster CG, Heeren RM. Structural analysis of synthetic homo- and copolyesters by electrospray ionization on a fourier transform ion cyclotron resonance mass spectrometer Journal of Mass Spectrometry : Jms. 35: 739-48. PMID 10862127 DOI: 10.1002/1096-9888(200006)35:6<739::Aid-Jms3>3.0.Co;2-#  0.591
2000 Koster S, Duursma MC, Boon JJ, Heeren RM. Endgroup determination of synthetic polymers by electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry Journal of the American Society For Mass Spectrometry. 11: 536-43. PMID 10833027 DOI: 10.1016/S1044-0305(00)00115-X  0.647
1999 Drahos L, Heeren RM, Collette C, De Pauw E, Vekey K. Thermal energy distribution observed in electrospray ionization Journal of Mass Spectrometry : Jms. 34: 1373-9. PMID 10587635 DOI: 10.1002/(Sici)1096-9888(199912)34:12<1373::Aid-Jms907>3.0.Co;2-#  0.348
1998 van Rooij GJ, Duursma MC, de Koster CG, Heeren RM, Boon JJ, Schuyl PJ, van der Hage ER. Determination of Block Length Distributions of Poly(oxypropylene) and Poly(oxyethylene) Block Copolymers by MALDI-FTICR Mass Spectrometry. Analytical Chemistry. 70: 843-50. PMID 21644616 DOI: 10.1021/Ac970609R  0.595
1996 van Rooij GJ, Duursma MC, Heeren RM, Boon JJ, de Koster CG. High resolution end group determination of low molecular weight polymers by matrix-assisted laser desorption ionization on an external ion source fourier transform ion cyclotron resonance mass spectrometer. Journal of the American Society For Mass Spectrometry. 7: 449-57. PMID 24203399 DOI: 10.1016/1044-0305(96)00003-7  0.625
1995 de Koster CG, Duursma MC, van Rooij GJ, Heeren RM, Boon JJ. Endgroup analysis of polyethylene glycol polymers by matrix-assisted laser desorption/ionization Fourier-transform ion cyclotron resonance mass spectrometry. Rapid Communications in Mass Spectrometry : Rcm. 9: 957-62. PMID 7670157 DOI: 10.1002/rcm.1290091018  0.622
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