Toshio Ohshima - Publications

Affiliations: 
Life Science & Medical Bioscience Waseda University, Shinjuku-ku, Tōkyō-to, Japan 

100 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Takahashi M, Nakabayashi T, Mita N, Jin X, Aikawa Y, Sasamoto K, Miyoshi G, Miyata M, Inoue T, Ohshima T. Involvement of Cdk5 activating subunit p35 in synaptic plasticity in excitatory and inhibitory neurons. Molecular Brain. 15: 37. PMID 35484559 DOI: 10.1186/s13041-022-00922-x  0.335
2021 Yamazaki Y, Moizumi M, Nagai J, Hatashita Y, Cai T, Kolattukudy P, Inoue T, Goshima Y, Ohshima T. Requirement of CRMP2 Phosphorylation in Neuronal Migration of Developing Mouse Cerebral Cortex and Hippocampus and Redundant Roles of CRMP1 and CRMP4. Cerebral Cortex (New York, N.Y. : 1991). PMID 34297816 DOI: 10.1093/cercor/bhab228  0.341
2021 Kawashima T, Jitsuki-Takahashi A, Takizawa K, Jitsuki S, Takahashi T, Ohshima T, Goshima Y, Nakamura F. Phosphorylation of Collapsin Response Mediator Protein 1 (CRMP1) at Tyrosine 504 residue regulates Semaphorin 3A-induced cortical dendritic growth. Journal of Neurochemistry. PMID 33449368 DOI: 10.1111/jnc.15304  0.364
2021 Sugeno A, Piao W, Yamazaki M, Takahashi K, Arikawa K, Matsunaga H, Hosokawa M, Tominaga D, Goshima Y, Takeyama H, Ohshima T. Cortical transcriptome analysis after spinal cord injury reveals the regenerative mechanism of central nervous system in CRMP2 knock-in mice. Neural Regeneration Research. 16: 1258-1265. PMID 33318403 DOI: 10.4103/1673-5374.301035  0.309
2020 Kiyooka M, Shimizu Y, Ohshima T. Histone deacetylase inhibition promotes regenerative neurogenesis after stab wound injury in the adult zebrafish optic tectum. Biochemical and Biophysical Research Communications. 529: 366-371. PMID 32703437 DOI: 10.1016/J.Bbrc.2020.06.025  0.315
2020 Nakamura F, Ohshima T, Goshima Y. Collapsin Response Mediator Proteins: Their Biological Functions and Pathophysiology in Neuronal Development and Regeneration. Frontiers in Cellular Neuroscience. 14: 188. PMID 32655376 DOI: 10.3389/Fncel.2020.00188  0.375
2020 Li W, Goshima Y, Ohshima T. Loss of Collapsin Response Mediator Protein 4 Attenuates 6-Hydroxydopamine-Induced Impairments in a Mouse Model of Parkinson's Disease. Neurochemical Research. PMID 32648145 DOI: 10.1007/S11064-020-03086-Z  0.314
2020 Fujita H, Oikawa R, Hayakawa M, Tomoike F, Kimura Y, Okuno H, Hatashita Y, Fiallos Oliveros C, Bito H, Ohshima T, Tsuneda S, Abe H, Inoue T. Quantification of native mRNA dynamics in living neurons using fluorescence correlation spectroscopy and reduction-triggered fluorescent probes. The Journal of Biological Chemistry. PMID 32341124 DOI: 10.1074/Jbc.Ra119.010921  0.309
2020 Togashi K, Hasegawa M, Nagai J, Kotaka K, Yazawa A, Takahashi M, Masukawa D, Goshima Y, Hensley K, Ohshima T. Lanthionine ketimine ester improves outcome in an MPTP-induced mouse model of Parkinson's disease via suppressions of CRMP2 phosphorylation and microglial activation. Journal of the Neurological Sciences. 413: 116802. PMID 32244093 DOI: 10.1016/J.Jns.2020.116802  0.35
2020 Yamazaki Y, Nagai J, Akinaga S, Koga Y, Hasegawa M, Takahashi M, Yamashita N, Kolattukudy P, Goshima Y, Ohshima T. Phosphorylation of CRMP2 is required for migration and positioning of Purkinje cells: redundant roles of CRMP1 and CRMP4. Brain Research. 146762. PMID 32156571 DOI: 10.1016/J.Brainres.2020.146762  0.432
2019 Kondo S, Takahashi K, Kinoshita Y, Nagai J, Wakatsuki S, Araki T, Goshima Y, Ohshima T. Genetic inhibition of CRMP2 phosphorylation at serine 522 promotes axonal regeneration after optic nerve injury. Scientific Reports. 9: 7188. PMID 31076621 DOI: 10.1038/S41598-019-43658-W  0.319
2018 Togashi K, Hasegawa M, Nagai J, Tonouchi A, Masukawa D, Hensley K, Goshima Y, Ohshima T. Genetic suppression of CRMP2 phosphorylation improves outcome in MPTP-induced Parkinson's model mice. Genes to Cells : Devoted to Molecular & Cellular Mechanisms. PMID 30375127 DOI: 10.1111/Gtc.12651  0.351
2018 Numata-Uematsu Y, Wakatsuki S, Nagano S, Shibata M, Sakai K, Ichinohe N, Mikoshiba K, Ohshima T, Yamashita N, Goshima Y, Araki T. Inhibition of collapsin response mediator protein-2 phosphorylation ameliorates motor phenotype of ALS model mice expressing SOD1G93A. Neuroscience Research. PMID 30194029 DOI: 10.1016/J.Neures.2018.08.016  0.387
2018 Ueda Y, Shimizu Y, Shimizu N, Ishitani T, Ohshima T. Involvement of Sonic hedgehog and Notch signaling in regenerative neurogenesis in adult zebrafish optic tectum after stab injury. The Journal of Comparative Neurology. PMID 30014463 DOI: 10.1002/Cne.24489  0.316
2018 Kamiki E, Boehringer R, Polygalov D, Ohshima T, McHugh TJ. Inducible Knockout of the Cyclin-Dependent Kinase 5 Activator p35 Alters Hippocampal Spatial Coding and Neuronal Excitability. Frontiers in Cellular Neuroscience. 12: 138. PMID 29867369 DOI: 10.3389/Fncel.2018.00138  0.63
2018 Nakamura H, Takahashi-Jitsuki A, Makihara H, Asano T, Kimura Y, Nakabayashi J, Yamashita N, Kawamoto Y, Nakamura F, Ohshima T, Hirano H, Tanaka F, Goshima Y. Proteome and behavioral alternations in phosphorylation-deficient mutant Collapsin Response Mediator Protein2 knock-in mice. Neurochemistry International. PMID 29758318 DOI: 10.1016/J.Neuint.2018.04.009  0.412
2018 Kuroki S, Yoshida T, Tsutsui H, Iwama M, Ando R, Michikawa T, Miyawaki A, Ohshima T, Itohara S. Excitatory Neuronal Hubs Configure Multisensory Integration of Slow Waves in Association Cortex. Cell Reports. 22: 2873-2885. PMID 29539417 DOI: 10.1016/J.Celrep.2018.02.056  0.317
2018 Chiang MC, Huang AJY, Wintzer ME, Ohshima T, McHugh TJ. A role for CA3 in social recognition memory. Behavioural Brain Research. PMID 29355673 DOI: 10.1016/J.Bbr.2018.01.019  0.642
2017 Nakamura F, Okada T, Shishikura M, Uetani N, Taniguchi M, Yagi T, Iwakura Y, Ohshima T, Goshima Y, Strittmatter SM. Protein Tyrosine Phosphatase δ mediates the Sema3A-induced cortical basal dendritic arborization through the activation of Fyn tyrosine kinase. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 28637841 DOI: 10.1523/Jneurosci.2519-16.2017  0.41
2017 Xu B, Kumazawa A, Kobayashi S, Hisanaga SI, Inoue T, Ohshima T. Cdk5 activity is required for Purkinje cell dendritic growth in cell-autonomous and non-cell-autonomous manners. Developmental Neurobiology. PMID 28589675 DOI: 10.1002/Dneu.22507  0.402
2017 Tobe BTD, Crain AM, Winquist AM, Calabrese B, Makihara H, Zhao WN, Lalonde J, Nakamura H, Konopaske G, Sidor M, Pernia CD, Yamashita N, Wada M, Inoue Y, Nakamura F, ... ... Ohshima T, et al. Probing the lithium-response pathway in hiPSCs implicates the phosphoregulatory set-point for a cytoskeletal modulator in bipolar pathogenesis. Proceedings of the National Academy of Sciences of the United States of America. PMID 28500272 DOI: 10.1073/Pnas.1700111114  0.392
2017 Nozawa K, Lin Y, Kubodera R, Shimizu Y, Tanaka H, Ohshima T. Zebrafish Mecp2 is required for proper axonal elongation of motor neurons and synapse formation. Developmental Neurobiology. PMID 28371371 DOI: 10.1002/Dneu.22498  0.375
2017 Takamura R, Watamura N, Nikkuni M, Ohshima T. All-trans retinoic acid improved impaired proliferation of neural stem cells and suppressed microglial activation in the hippocampus in an Alzheimer's mouse model. Journal of Neuroscience Research. 95: 897-906. PMID 27448243 DOI: 10.1002/Jnr.23843  0.348
2016 Abdallah BM, Figeac F, Larsen KH, Ditzel N, Keshari P, Isa A, Jafari A, Andersen TL, Delaisse JM, Goshima Y, Ohshima T, Kassem M. CRMP4 Inhibits Bone Formation by Negatively Regulating BMP and RhoA Signaling. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 28019696 DOI: 10.1002/Jbmr.3069  0.321
2016 Takaya R, Nagai J, Piao W, Niisato E, Nakabayashi T, Yamazaki Y, Nakamura F, Yamashita N, Kolattukudy P, Goshima Y, Ohshima T. CRMP1 and CRMP4 are required for proper orientation of dendrites of cerebral pyramidal neurons in the developing mouse brain. Brain Research. PMID 27836492 DOI: 10.1016/J.Brainres.2016.11.003  0.446
2016 Sasamoto K, Nagai J, Nakabayashi T, He X, Ohshima T. Cdk5 is required for the positioning and survival of GABAergic neurons in developing mouse striatum. Developmental Neurobiology. PMID 27480591 DOI: 10.1002/Dneu.22424  0.463
2016 Nagai J, Baba R, Ohshima T. CRMPs Function in Neurons and Glial Cells: Potential Therapeutic Targets for Neurodegenerative Diseases and CNS Injury. Molecular Neurobiology. PMID 27339876 DOI: 10.1007/S12035-016-0005-1  0.384
2016 Toba J, Nikkuni M, Ishizeki M, Yoshii A, Watamura N, Inoue T, Ohshima T. PPARγ agonist pioglitazone improves cerebellar dysfunction at pre-Aβ deposition stage in APPswe/PS1dE9 Alzheimer's disease model mice. Biochemical and Biophysical Research Communications. PMID 27059136 DOI: 10.1016/J.Bbrc.2016.04.012  0.318
2016 Nagai J, Takaya R, Piao W, Goshima Y, Ohshima T. Deletion of Crmp4 attenuates CSPG-induced inhibition of axonal growth and induces nociceptive recovery after spinal cord injury. Molecular and Cellular Neurosciences. 74: 42-8. PMID 26995506 DOI: 10.1016/J.Mcn.2016.03.006  0.381
2016 Tonouchi A, Nagai J, Togashi K, Goshima Y, Ohshima T. Loss of collapsin response mediator protein 4 suppresses dopaminergic neuron death in an 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced mouse model of Parkinson's disease. Journal of Neurochemistry. 137: 795-805. PMID 26991935 DOI: 10.1111/Jnc.13617  0.389
2016 Jin X, Sasamoto K, Nagai J, Yamazaki Y, Saito K, Goshima Y, Inoue T, Ohshima T. Phosphorylation of CRMP2 by Cdk5 Regulates Dendritic Spine Development of Cortical Neuron in the Mouse Hippocampus. Neural Plasticity. 2016: 6790743. PMID 26819770 DOI: 10.1155/2016/6790743  0.476
2016 Nagai J, Owada K, Kitamura Y, Goshima Y, Ohshima T. Inhibition of CRMP2 phosphorylation repairs CNS by regulating neurotrophic and inhibitory responses. Experimental Neurology. 277: 283-295. PMID 26795088 DOI: 10.1016/J.Expneurol.2016.01.015  0.416
2016 Watamura N, Toba J, Yoshii A, Nikkuni M, Ohshima T. Colocalization of phosphorylated forms of WAVE1, CRMP2, and tau in Alzheimer's disease model mice: Involvement of Cdk5 phosphorylation and the effect of ATRA treatment. Journal of Neuroscience Research. 94: 15-26. PMID 26400044 DOI: 10.1002/Jnr.23674  0.349
2016 Mita N, He X, Sasamoto K, Mishiba T, Ohshima T. Cyclin-Dependent Kinase 5 Regulates Dendritic Spine Formation and Maintenance of Cortical Neuron in the Mouse Brain. Cerebral Cortex (New York, N.Y. : 1991). 26: 967-976. PMID 25404468 DOI: 10.1093/Cercor/Bhu264  0.452
2016 Mita N, He X, Sasamoto K, Mishiba T, Ohshima T. Cyclin-Dependent Kinase 5 Regulates Dendritic Spine Formation and Maintenance of Cortical Neuron in the Mouse Brain Cerebral Cortex. 26: 967-976. DOI: 10.1093/cercor/bhu264  0.333
2015 Shimizu Y, Ito Y, Tanaka H, Ohshima T. Radial glial cell-specific ablation in the adult Zebrafish brain. Genesis (New York, N.Y. : 2000). 53: 431-9. PMID 26045148 DOI: 10.1002/Dvg.22865  0.315
2015 Nagai J, Kitamura Y, Owada K, Yamashita N, Takei K, Goshima Y, Ohshima T. Crmp4 deletion promotes recovery from spinal cord injury by neuroprotection and limited scar formation. Scientific Reports. 5: 8269. PMID 25652774 DOI: 10.1038/Srep08269  0.306
2014 Ohshima T. Neuronal migration and protein kinases. Frontiers in Neuroscience. 8: 458. PMID 25628530 DOI: 10.3389/Fnins.2014.00458  0.429
2014 Mishiba T, Tanaka M, Mita N, He X, Sasamoto K, Itohara S, Ohshima T. Cdk5/p35 functions as a crucial regulator of spatial learning and memory. Molecular Brain. 7: 82. PMID 25404232 DOI: 10.1186/S13041-014-0082-X  0.415
2014 Nishimura YV, Shikanai M, Hoshino M, Ohshima T, Nabeshima Y, Mizutani K, Nagata K, Nakajima K, Kawauchi T. Cdk5 and its substrates, Dcx and p27kip1, regulate cytoplasmic dilation formation and nuclear elongation in migrating neurons. Development (Cambridge, England). 141: 3540-50. PMID 25183872 DOI: 10.1242/Dev.111294  0.406
2014 Kobayashi H, Saito T, Sato K, Furusawa K, Hosokawa T, Tsutsumi K, Asada A, Kamada S, Ohshima T, Hisanaga S. Phosphorylation of cyclin-dependent kinase 5 (Cdk5) at Tyr-15 is inhibited by Cdk5 activators and does not contribute to the activation of Cdk5. The Journal of Biological Chemistry. 289: 19627-36. PMID 24872417 DOI: 10.1074/Jbc.M113.501148  0.414
2014 He X, Ishizeki M, Mita N, Wada S, Araki Y, Ogura H, Abe M, Yamazaki M, Sakimura K, Mikoshiba K, Inoue T, Ohshima T. Cdk5/p35 is required for motor coordination and cerebellar plasticity. Journal of Neurochemistry. 131: 53-64. PMID 24802945 DOI: 10.1111/Jnc.12756  0.358
2014 Takahashi M, Ishida M, Saito T, Ohshima T, Hisanaga S. Valproic acid downregulates Cdk5 activity via the transcription of the p35 mRNA. Biochemical and Biophysical Research Communications. 447: 678-82. PMID 24755075 DOI: 10.1016/J.Bbrc.2014.04.072  0.411
2014 Tanabe K, Yamazaki H, Inaguma Y, Asada A, Kimura T, Takahashi J, Taoka M, Ohshima T, Furuichi T, Isobe T, Nagata K, Shirao T, Hisanaga S. Phosphorylation of drebrin by cyclin-dependent kinase 5 and its role in neuronal migration. Plos One. 9: e92291. PMID 24637538 DOI: 10.1371/Journal.Pone.0092291  0.44
2014 Utreras E, Hamada R, Prochazkova M, Terse A, Takahashi S, Ohshima T, Kulkarni AB. Suppression of neuroinflammation in forebrain-specific Cdk5 conditional knockout mice by PPARγ agonist improves neuronal loss and early lethality. Journal of Neuroinflammation. 11: 28. PMID 24495352 DOI: 10.1186/1742-2094-11-28  0.456
2014 Nishimura YV, Shikanai M, Hoshino M, Ohshima T, Nabeshima Y, Mizutani K, Nagata K, Nakajima K, Kawauchi T. Cdk5 and its substrates, Dcx and p27kip1, regulate the formation of cytoplasmic dilation and nuclear elongation in migrating neurons Journal of Cell Science. 127. DOI: 10.1242/Jcs.162693  0.382
2013 Kwak Y, Jeong J, Lee S, Park YU, Lee SA, Han DH, Kim JH, Ohshima T, Mikoshiba K, Suh YH, Cho S, Park SK. Cyclin-dependent kinase 5 (Cdk5) regulates the function of CLOCK protein by direct phosphorylation. The Journal of Biological Chemistry. 288: 36878-89. PMID 24235147 DOI: 10.1074/Jbc.M113.494856  0.344
2013 Hisatsune C, Miyamoto H, Hirono M, Yamaguchi N, Sugawara T, Ogawa N, Ebisui E, Ohshima T, Yamada M, Hensch TK, Hattori M, Mikoshiba K. IP3R1 deficiency in the cerebellum/brainstem causes basal ganglia-independent dystonia by triggering tonic Purkinje cell firings in mice. Frontiers in Neural Circuits. 7: 156. PMID 24109434 DOI: 10.3389/Fncir.2013.00156  0.354
2013 Isono T, Yamashita N, Obara M, Araki T, Nakamura F, Kamiya Y, Alkam T, Nitta A, Nabeshima T, Mikoshiba K, Ohshima T, Goshima Y. Amyloid-β₂₅₋₃₅ induces impairment of cognitive function and long-term potentiation through phosphorylation of collapsin response mediator protein 2. Neuroscience Research. 77: 180-5. PMID 23994236 DOI: 10.1016/J.Neures.2013.08.005  0.358
2013 Morimura R, Nozawa K, Tanaka H, Ohshima T. Phosphorylation of Dpsyl2 (CRMP2) and Dpsyl3 (CRMP4) is required for positioning of caudal primary motor neurons in the zebrafish spinal cord. Developmental Neurobiology. 73: 911-20. PMID 23929741 DOI: 10.1002/Dneu.22117  0.362
2013 Jang A, Liew H, Kim YM, Choi H, Kim S, Lee SH, Ohshima T, Mikoshiba K, Suh YH. p35 deficiency accelerates HMGB-1-mediated neuronal death in the early stages of an Alzheimer's disease mouse model. Current Alzheimer Research. 10: 829-43. PMID 23905994 DOI: 10.2174/15672050113109990135  0.426
2013 Huilgol D, Udin S, Shimogori T, Saha B, Roy A, Aizawa S, Hevner RF, Meyer G, Ohshima T, Pleasure SJ, Zhao Y, Tole S. Dual origins of the mammalian accessory olfactory bulb revealed by an evolutionarily conserved migratory stream. Nature Neuroscience. 16: 157-65. PMID 23292680 DOI: 10.1038/Nn.3297  0.363
2013 Kumazawa A, Mita N, Hirasawa M, Adachi T, Suzuki H, Shafeghat N, Kulkarni AB, Mikoshiba K, Inoue T, Ohshima T. Cyclin-dependent kinase 5 is required for normal cerebellar development. Molecular and Cellular Neurosciences. 52: 97-105. PMID 23085039 DOI: 10.1016/J.Mcn.2012.10.007  0.474
2013 Niisato E, Nagai J, Yamashita N, Nakamura F, Goshima Y, Ohshima T. Phosphorylation of CRMP2 is involved in proper bifurcation of the apical dendrite of hippocampal CA1 pyramidal neurons. Developmental Neurobiology. 73: 142-51. PMID 22826151 DOI: 10.1002/Dneu.22048  0.468
2012 Tanaka H, Morimura R, Ohshima T. Dpysl2 (CRMP2) and Dpysl3 (CRMP4) phosphorylation by Cdk5 and DYRK2 is required for proper positioning of Rohon-Beard neurons and neural crest cells during neurulation in zebrafish. Developmental Biology. 370: 223-36. PMID 22898304 DOI: 10.1016/J.Ydbio.2012.07.032  0.415
2012 Terabayashi T, Sakaguchi M, Shinmyozu K, Ohshima T, Johjima A, Ogura T, Miki H, Nishinakamura R. Phosphorylation of Kif26b promotes its polyubiquitination and subsequent proteasomal degradation during kidney development. Plos One. 7: e39714. PMID 22768111 DOI: 10.1371/Journal.Pone.0039714  0.365
2012 Nagai J, Goshima Y, Ohshima T. CRMP4 mediates MAG-induced inhibition of axonal outgrowth and protection against Vincristine-induced axonal degeneration. Neuroscience Letters. 519: 56-61. PMID 22583768 DOI: 10.1016/J.Neulet.2012.05.020  0.305
2012 Yamashita N, Ohshima T, Nakamura F, Kolattukudy P, Honnorat J, Mikoshiba K, Goshima Y. Phosphorylation of CRMP2 (collapsin response mediator protein 2) is involved in proper dendritic field organization. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 1360-5. PMID 22279220 DOI: 10.1523/Jneurosci.5563-11.2012  0.437
2012 Niisato E, Nagai J, Yamashita N, Abe T, Kiyonari H, Goshima Y, Ohshima T. CRMP4 suppresses apical dendrite bifurcation of CA1 pyramidal neurons in the mouse hippocampus. Developmental Neurobiology. 72: 1447-57. PMID 22234963 DOI: 10.1002/Dneu.22007  0.458
2011 He X, Takahashi S, Suzuki H, Hashikawa T, Kulkarni AB, Mikoshiba K, Ohshima T. Hypomyelination phenotype caused by impaired differentiation of oligodendrocytes in Emx1-cre mediated Cdk5 conditional knockout mice. Neurochemical Research. 36: 1293-303. PMID 21210220 DOI: 10.1007/S11064-010-0391-0  0.451
2011 Tanaka H, Nojima Y, Shoji W, Sato M, Nakayama R, Ohshima T, Okamoto H. Islet1 selectively promotes peripheral axon outgrowth in Rohon-Beard primary sensory neurons. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 240: 9-22. PMID 21108318 DOI: 10.1002/Dvdy.22499  0.356
2011 Hisatsune C, Miyamoto H, Hirono M, Yamaguchi N, Sugawara T, Ogawa N, Ohshima T, Yamada M, Hensch TK, Hattori M, Mikoshiba K. Disturbed Purkinje cell spike activity produces dystonia in mice lacking the type 1 inositol 1,4,5-trisphosphate receptor Neuroscience Research. 71: e99. DOI: 10.1016/J.Neures.2011.07.425  0.32
2010 Jin J, Suzuki H, Hirai S, Mikoshiba K, Ohshima T. JNK phosphorylates Ser332 of doublecortin and regulates its function in neurite extension and neuronal migration. Developmental Neurobiology. 70: 929-42. PMID 20715151 DOI: 10.1016/J.Neures.2010.07.1110  0.443
2010 Tsutsumi K, Takano T, Endo R, Fukuda M, Ohshima T, Tomomura M, Hisanaga S. Phosphorylation of AATYK1 by Cdk5 suppresses its tyrosine phosphorylation. Plos One. 5: e10260. PMID 20422042 DOI: 10.1371/Journal.Pone.0010260  0.414
2010 Ito Y, Tanaka H, Okamoto H, Ohshima T. Characterization of neural stem cells and their progeny in the adult zebrafish optic tectum. Developmental Biology. 342: 26-38. PMID 20346355 DOI: 10.1016/J.Ydbio.2010.03.008  0.324
2010 Takahashi S, Ohshima T, Hirasawa M, Pareek TK, Bugge TH, Morozov A, Fujieda K, Brady RO, Kulkarni AB. Conditional deletion of neuronal cyclin-dependent kinase 5 in developing forebrain results in microglial activation and neurodegeneration. The American Journal of Pathology. 176: 320-9. PMID 19948833 DOI: 10.2353/Ajpath.2010.081158  0.441
2010 Niisato E, Yamashita N, Nakamura F, Goshima Y, Ohshima T. Role of collapsin response mediator proteins for dendritic development in hippocampal CA1 pyramidal neurons Neuroscience Research. 68: e250-e251. DOI: 10.1016/J.Neures.2010.07.1111  0.401
2009 Nakamura F, Ugajin K, Yamashita N, Okada T, Uchida Y, Taniguchi M, Ohshima T, Goshima Y. Increased proximal bifurcation of CA1 pyramidal apical dendrites in sema3A mutant mice. The Journal of Comparative Neurology. 516: 360-75. PMID 19655386 DOI: 10.1002/Cne.22125  0.463
2009 Uchida Y, Ohshima T, Yamashita N, Ogawara M, Sasaki Y, Nakamura F, Goshima Y. Semaphorin3A signaling mediated by Fyn-dependent tyrosine phosphorylation of collapsin response mediator protein 2 at tyrosine 32. The Journal of Biological Chemistry. 284: 27393-401. PMID 19652227 DOI: 10.1074/Jbc.M109.000240  0.419
2009 Endo R, Saito T, Asada A, Kawahara H, Ohshima T, Hisanaga S. Commitment of 1-methyl-4-phenylpyrinidinium ion-induced neuronal cell death by proteasome-mediated degradation of p35 cyclin-dependent kinase 5 activator. The Journal of Biological Chemistry. 284: 26029-39. PMID 19638632 DOI: 10.1074/Jbc.M109.026443  0.392
2009 Nakamura F, Ugajin K, Yamashita N, Taniguchi M, Ohshima T, Goshima Y. Sema3A regulates apical dendritic growth of hippocamal CA1 pyramidal neurons Neuroscience Research. 65. DOI: 10.1016/J.Neures.2009.09.076  0.382
2008 Kaminosono S, Saito T, Oyama F, Ohshima T, Asada A, Nagai Y, Nukina N, Hisanaga S. Suppression of mutant Huntingtin aggregate formation by Cdk5/p35 through the effect on microtubule stability. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 8747-55. PMID 18753376 DOI: 10.1523/Jneurosci.0973-08.2008  0.373
2007 Hirota Y, Ohshima T, Kaneko N, Ikeda M, Iwasato T, Kulkarni AB, Mikoshiba K, Okano H, Sawamoto K. Cyclin-dependent kinase 5 is required for control of neuroblast migration in the postnatal subventricular zone. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 12829-38. PMID 18032654 DOI: 10.1523/Jneurosci.1014-07.2007  0.412
2007 Yamashita N, Morita A, Uchida Y, Nakamura F, Usui H, Ohshima T, Taniguchi M, Honnorat J, Thomasset N, Takei K, Takahashi T, Kolattukudy P, Goshima Y. Regulation of spine development by semaphorin3A through cyclin-dependent kinase 5 phosphorylation of collapsin response mediator protein 1. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 12546-54. PMID 18003833 DOI: 10.1523/Jneurosci.3463-07.2007  0.473
2007 Remedios R, Huilgol D, Saha B, Hari P, Bhatnagar L, Kowalczyk T, Hevner RF, Suda Y, Aizawa S, Ohshima T, Stoykova A, Tole S. A stream of cells migrating from the caudal telencephalon reveals a link between the amygdala and neocortex. Nature Neuroscience. 10: 1141-50. PMID 17694053 DOI: 10.1038/Nn1955  0.364
2007 Ohshima T, Hirasawa M, Tabata H, Mutoh T, Adachi T, Suzuki H, Saruta K, Iwasato T, Itohara S, Hashimoto M, Nakajima K, Ogawa M, Kulkarni AB, Mikoshiba K. Cdk5 is required for multipolar-to-bipolar transition during radial neuronal migration and proper dendrite development of pyramidal neurons in the cerebral cortex. Development (Cambridge, England). 134: 2273-82. PMID 17507397 DOI: 10.1242/Dev.02854  0.42
2007 Hayashi K, Ohshima T, Hashimoto M, Mikoshiba K. Pak1 regulates dendritic branching and spine formation. Developmental Neurobiology. 67: 655-69. PMID 17443815 DOI: 10.1002/Dneu.20363  0.439
2007 Ohshima T, Suzuki H, Morimura T, Ogawa M, Mikoshiba K. Modulation of Reelin signaling by Cyclin-dependent kinase 5. Brain Research. 1140: 84-95. PMID 16529723 DOI: 10.1016/J.Brainres.2006.01.121  0.407
2007 Uchida Y, Ohshima T, Yamashita N, Nakamura F, Kolattukudy P, Honnorat J, Goshima Y. Phosphorylation of CRMP2 at S522 is required for proper dendritic patterning of layer V cortical neurons in vivo Neuroscience Research. 58: S203. DOI: 10.1016/J.Neures.2007.06.921  0.365
2006 Yamashita N, Uchida Y, Ohshima T, Hirai S, Nakamura F, Taniguchi M, Mikoshiba K, Honnorat J, Kolattukudy P, Thomasset N, Takei K, Takahashi T, Goshima Y. Collapsin response mediator protein 1 mediates reelin signaling in cortical neuronal migration. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 13357-62. PMID 17182786 DOI: 10.1523/Jneurosci.4276-06.2006  0.417
2006 Hayashi K, Pan Y, Shu H, Ohshima T, Kansy JW, White CL, Tamminga CA, Sobel A, Curmi PA, Mikoshiba K, Bibb JA. Phosphorylation of the tubulin-binding protein, stathmin, by Cdk5 and MAP kinases in the brain. Journal of Neurochemistry. 99: 237-50. PMID 16925597 DOI: 10.1111/J.1471-4159.2006.04113.X  0.431
2006 Hosokawa T, Saito T, Asada A, Ohshima T, Itakura M, Takahashi M, Fukunaga K, Hisanaga S. Enhanced activation of Ca2+/calmodulin-dependent protein kinase II upon downregulation of cyclin-dependent kinase 5-p35. Journal of Neuroscience Research. 84: 747-54. PMID 16802322 DOI: 10.1002/Jnr.20975  0.411
2005 Ohshima T, Ogura H, Tomizawa K, Hayashi K, Suzuki H, Saito T, Kamei H, Nishi A, Bibb JA, Hisanaga S, Matsui H, Mikoshiba K. Impairment of hippocampal long-term depression and defective spatial learning and memory in p35 mice. Journal of Neurochemistry. 94: 917-25. PMID 15992381 DOI: 10.1111/J.1471-4159.2005.03233.X  0.431
2005 Wei FY, Tomizawa K, Ohshima T, Asada A, Saito T, Nguyen C, Bibb JA, Ishiguro K, Kulkarni AB, Pant HC, Mikoshiba K, Matsui H, Hisanaga S. Control of cyclin-dependent kinase 5 (Cdk5) activity by glutamatergic regulation of p35 stability. Journal of Neurochemistry. 93: 502-12. PMID 15816873 DOI: 10.1111/J.1471-4159.2005.03058.X  0.397
2005 Uchida Y, Ohshima T, Sasaki Y, Suzuki H, Yanai S, Yamashita N, Nakamura F, Takei K, Ihara Y, Mikoshiba K, Kolattukudy P, Honnorat J, Goshima Y. Semaphorin3A signalling is mediated via sequential Cdk5 and GSK3beta phosphorylation of CRMP2: implication of common phosphorylating mechanism underlying axon guidance and Alzheimer's disease. Genes to Cells : Devoted to Molecular & Cellular Mechanisms. 10: 165-79. PMID 15676027 DOI: 10.1111/J.1365-2443.2005.00827.X  0.383
2005 Takahashi S, Ohshima T, Cho A, Sreenath T, Iadarola MJ, Pant HC, Kim Y, Nairn AC, Brady RO, Greengard P, Kulkarni AB. Increased activity of cyclin-dependent kinase 5 leads to attenuation of cocaine-mediated dopamine signaling. Proceedings of the National Academy of Sciences of the United States of America. 102: 1737-42. PMID 15665076 DOI: 10.1073/Pnas.0409456102  0.347
2004 Li C, Sasaki Y, Takei K, Yamamoto H, Shouji M, Sugiyama Y, Kawakami T, Nakamura F, Yagi T, Ohshima T, Goshima Y. Correlation between semaphorin3A-induced facilitation of axonal transport and local activation of a translation initiation factor eukaryotic translation initiation factor 4E. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 6161-70. PMID 15240808 DOI: 10.1523/Jneurosci.1476-04.2004  0.387
2004 Hirasawa M, Ohshima T, Takahashi S, Longenecker G, Honjo Y, Veeranna, Pant HC, Mikoshiba K, Brady RO, Kulkarni AB. Perinatal abrogation of Cdk5 expression in brain results in neuronal migration defects. Proceedings of the National Academy of Sciences of the United States of America. 101: 6249-54. PMID 15067135 DOI: 10.1073/Pnas.0307322101  0.466
2003 Tomizawa K, Sunada S, Lu YF, Oda Y, Kinuta M, Ohshima T, Saito T, Wei FY, Matsushita M, Li ST, Tsutsui K, Hisanaga S, Mikoshiba K, Takei K, Matsui H. Cophosphorylation of amphiphysin I and dynamin I by Cdk5 regulates clathrin-mediated endocytosis of synaptic vesicles. The Journal of Cell Biology. 163: 813-24. PMID 14623869 DOI: 10.1083/Jcb.200308110  0.444
2002 Ohshima T, Mikoshiba K. Reelin signaling and Cdk5 in the control of neuronal positioning. Molecular Neurobiology. 26: 153-66. PMID 12428753 DOI: 10.1385/Mn:26:2-3:153  0.421
2002 Sasaki Y, Cheng C, Uchida Y, Nakajima O, Ohshima T, Yagi T, Taniguchi M, Nakayama T, Kishida R, Kudo Y, Ohno S, Nakamura F, Goshima Y. Fyn and Cdk5 mediate semaphorin-3A signaling, which is involved in regulation of dendrite orientation in cerebral cortex. Neuron. 35: 907-20. PMID 12372285 DOI: 10.1016/S0896-6273(02)00857-7  0.424
2002 Hayashi K, Ohshima T, Mikoshiba K. Pak1 is involved in dendrite initiation as a downstream effector of Rac1 in cortical neurons. Molecular and Cellular Neurosciences. 20: 579-94. PMID 12213441 DOI: 10.1006/Mcne.2002.1144  0.45
2002 Ohshima T, Ogawa M, Takeuchi K, Takahashi S, Kulkarni AB, Mikoshiba K. Cyclin-dependent kinase 5/p35 contributes synergistically with Reelin/Dab1 to the positioning of facial branchiomotor and inferior olive neurons in the developing mouse hindbrain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 4036-44. PMID 12019323 DOI: 10.1523/Jneurosci.22-10-04036.2002  0.461
2001 Ohshima T, Ogawa M, Veeranna, Hirasawa M, Longenecker G, Ishiguro K, Pant HC, Brady RO, Kulkarni AB, Mikoshiba K. Synergistic contributions of cyclin-dependant kinase 5/p35 and Reelin/Dab1 to the positioning of cortical neurons in the developing mouse brain. Proceedings of the National Academy of Sciences of the United States of America. 98: 2764-9. PMID 11226314 DOI: 10.1073/Pnas.051628498  0.46
2001 Tanaka T, Veeranna, Ohshima T, Rajan P, Amin ND, Cho A, Sreenath T, Pant HC, Brady RO, Kulkarni AB. Neuronal cyclin-dependent kinase 5 activity is critical for survival. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 550-8. PMID 11160434 DOI: 10.1523/Jneurosci.21-02-00550.2001  0.457
1999 Ohshima T, Gilmore EC, Longenecker G, Jacobowitz DM, Brady RO, Herrup K, Kulkarni AB. Migration defects of cdk5(-/-) neurons in the developing cerebellum is cell autonomous. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 6017-26. PMID 10407039 DOI: 10.1523/Jneurosci.19-14-06017.1999  0.421
1998 Gilmore EC, Ohshima T, Goffinet AM, Kulkarni AB, Herrup K. Cyclin-dependent kinase 5-deficient mice demonstrate novel developmental arrest in cerebral cortex. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 6370-7. PMID 9698328 DOI: 10.1523/Jneurosci.18-16-06370.1998  0.425
1996 Ohshima T, Ward JM, Huh CG, Longenecker G, Veeranna, Pant HC, Brady RO, Martin LJ, Kulkarni AB. Targeted disruption of the cyclin-dependent kinase 5 gene results in abnormal corticogenesis, neuronal pathology and perinatal death. Proceedings of the National Academy of Sciences of the United States of America. 93: 11173-8. PMID 8855328 DOI: 10.1073/Pnas.93.20.11173  0.472
1996 Ohshima T, Kozak CA, Nagle JW, Pant HC, Brady RO, Kulkarni AB. Molecular cloning and chromosomal mapping of the mouse gene encoding cyclin-dependent kinase 5 regulatory subunit p35. Genomics. 35: 372-5. PMID 8661152 DOI: 10.1006/Geno.1996.0370  0.334
1995 Ohshima T, Nagle JW, Pant HC, Joshi JB, Kozak CA, Brady RO, Kulkarni AB. Molecular cloning and chromosomal mapping of the mouse cyclin-dependent kinase 5 gene. Genomics. 28: 585-8. PMID 7490100 DOI: 10.1006/Geno.1995.1194  0.358
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