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Amy R. Nelson - Publications

Affiliations: 
University of Southern California, Los Angeles, CA, United States 
Area:
Alzheimer's, learning and memory, neurovasculature, pericytes
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24 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Kisler K, Sagare AP, Lazic D, Bazzi S, Lawson E, Hsu CJ, Wang Y, Ramanathan A, Nelson AR, Zhao Z, Zlokovic BV. Correction: Anti-malaria drug artesunate prevents development of amyloid-β pathology in mice by upregulating PICALM at the blood-brain barrier. Molecular Neurodegeneration. 18: 14. PMID 36829231 DOI: 10.1186/s13024-023-00606-7  0.448
2023 Kisler K, Sagare AP, Lazic D, Bazzi S, Lawson E, Hsu CJ, Wang Y, Ramanathan A, Nelson AR, Zhao Z, Zlokovic BV. Anti-malaria drug artesunate prevents development of amyloid-β pathology in mice by upregulating PICALM at the blood-brain barrier. Molecular Neurodegeneration. 18: 7. PMID 36707892 DOI: 10.1186/s13024-023-00597-5  0.504
2020 Nelson AR, Sagare MA, Wang Y, Kisler K, Zhao Z, Zlokovic BV. Channelrhodopsin Excitation Contracts Brain Pericytes and Reduces Blood Flow in the Aging Mouse Brain . Frontiers in Aging Neuroscience. 12: 108. PMID 32410982 DOI: 10.3389/Fnagi.2020.00108  0.536
2020 Montagne A, Nation DA, Sagare AP, Barisano G, Sweeney MD, Chakhoyan A, Pachicano M, Joe E, Nelson AR, D'Orazio LM, Buennagel DP, Harrington MG, Benzinger TLS, Fagan AM, Ringman JM, et al. APOE4 leads to blood-brain barrier dysfunction predicting cognitive decline. Nature. 581: 71-76. PMID 32376954 DOI: 10.1038/S41586-020-2247-3  0.567
2019 Dyer-Reaves K, Goodman AM, Nelson AR, McMahon LL. Alpha1-Adrenergic Receptor Mediated Long-Term Depression at CA3-CA1 Synapses Can Be Induced Accumulation of Endogenous Norepinephrine and Is Preserved Following Noradrenergic Denervation. Frontiers in Synaptic Neuroscience. 11: 27. PMID 31649525 DOI: 10.3389/Fnsyn.2019.00027  0.74
2019 Sagare AP, Sweeney MD, Nelson AR, Zhao Z, Zlokovic BV. Prion Protein Antagonists Rescue Alzheimer's Amyloid-β-Related Cognitive Deficits. Trends in Molecular Medicine. PMID 30661727 DOI: 10.1016/J.Molmed.2019.01.001  0.55
2019 Nation DA, Sweeney MD, Montagne A, Sagare AP, D'Orazio LM, Pachicano M, Sepehrband F, Nelson AR, Buennagel DP, Harrington MG, Benzinger TLS, Fagan AM, Ringman JM, Schneider LS, Morris JC, et al. Blood-brain barrier breakdown is an early biomarker of human cognitive dysfunction. Nature Medicine. PMID 30643288 DOI: 10.1038/S41591-018-0297-Y  0.576
2019 Sweeney MD, Zhao Z, Montagne A, Nelson AR, Zlokovic BV. Blood-Brain Barrier: From Physiology to Disease and Back. Physiological Reviews. 99: 21-78. PMID 30280653 DOI: 10.1152/Physrev.00050.2017  0.537
2019 Nelson AR, Sagare MA, Wang Y, Kisler K, Zhao Z, Zlokovic BV. P4-527: PERICYTE CONTRACTILITY BY OPTOGENETICS REGULATES CAPILLARY DIAMETER AND BLOOD FLOW Alzheimer's & Dementia. 15: P1516-P1516. DOI: 10.1016/J.Jalz.2019.08.074  0.457
2019 Kisler K, Sagare AP, Bazzi S, Lazic D, Hsu C, Lawson EJ, Nelson AR, Zhao Z, Zlokovic BV. UPREGULATION OF ENDOTHELIAL PICALM EXPRESSION USING AN FDA-APPROVED DRUG REDUCES AMYLOID-β LOAD IN THE MURINE BRAIN Alzheimer's & Dementia. 15: P245-P246. DOI: 10.1016/J.Jalz.2019.06.059  0.49
2018 Shi Y, Lin S, Staats KA, Li Y, Chang WH, Hung ST, Hendricks E, Linares GR, Wang Y, Son EY, Wen X, Kisler K, Wilkinson B, Menendez L, Sugawara T, ... ... Nelson AR, et al. Haploinsufficiency leads to neurodegeneration in C9ORF72 ALS/FTD human induced motor neurons. Nature Medicine. PMID 29400714 DOI: 10.1038/Nm.4490  0.507
2017 Amar AP, Sagare AP, Zhao Z, Wang Y, Nelson AR, Griffin JH, Zlokovic BV. Can adjunctive therapies augment the efficacy of endovascular thrombolysis? A potential role for activated protein C. Neuropharmacology. PMID 28923278 DOI: 10.1016/J.Neuropharm.2017.09.021  0.452
2017 Nelson AR, Sagare AP, Zlokovic BV. Role of clusterin in the brain vascular clearance of amyloid-β. Proceedings of the National Academy of Sciences of the United States of America. PMID 28765369 DOI: 10.1073/Pnas.1711357114  0.57
2017 Kisler K, Nelson AR, Montagne A, Zlokovic BV. Cerebral blood flow regulation and neurovascular dysfunction in Alzheimer disease. Nature Reviews. Neuroscience. PMID 28515434 DOI: 10.1038/Nrn.2017.48  0.539
2017 Kisler K, Nelson AR, Rege SV, Ramanathan A, Wang Y, Ahuja A, Lazic D, Tsai PS, Zhao Z, Zhou Y, Boas DA, Sakadžić S, Zlokovic BV. Pericyte degeneration leads to neurovascular uncoupling and limits oxygen supply to brain. Nature Neuroscience. PMID 28135240 DOI: 10.1038/Nn.4489  0.548
2015 Nelson AR, Sweeney MD, Sagare AP, Zlokovic BV. Neurovascular dysfunction and neurodegeneration in dementia and Alzheimer's disease. Biochimica Et Biophysica Acta. PMID 26705676 DOI: 10.1016/J.Bbadis.2015.12.016  0.572
2015 Zhao Z, Nelson AR, Betsholtz C, Zlokovic BV. Establishment and Dysfunction of the Blood-Brain Barrier. Cell. 163: 1064-78. PMID 26590417 DOI: 10.1016/J.Cell.2015.10.067  0.557
2015 Ramanathan A, Nelson AR, Sagare AP, Zlokovic BV. Impaired vascular-mediated clearance of brain amyloid beta in Alzheimer's disease: the role, regulation and restoration of LRP1. Frontiers in Aging Neuroscience. 7: 136. PMID 26236233 DOI: 10.3389/Fnagi.2015.00136  0.576
2015 Winkler EA, Nishida Y, Sagare AP, Rege SV, Bell RD, Perlmutter D, Sengillo JD, Hillman S, Kong P, Nelson AR, Sullivan JS, Zhao Z, Meiselman HJ, Wenby RB, Soto J, et al. GLUT1 reductions exacerbate Alzheimer's disease vasculo-neuronal dysfunction and degeneration. Nature Neuroscience. 18: 521-30. PMID 25730668 DOI: 10.1038/Nn.3966  0.557
2014 Taylor EW, Wang K, Nelson AR, Bredemann TM, Fraser KB, Clinton SM, Puckett R, Marchase RB, Chatham JC, McMahon LL. O-GlcNAcylation of AMPA receptor GluA2 is associated with a novel form of long-term depression at hippocampal synapses. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 10-21. PMID 24381264 DOI: 10.1523/Jneurosci.4761-12.2014  0.666
2014 Nelson AR, Kolasa K, McMahon LL. Noradrenergic sympathetic sprouting and cholinergic reinnervation maintains non-amyloidogenic processing of AβPP. Journal of Alzheimer's Disease : Jad. 38: 867-79. PMID 24081376 DOI: 10.3233/Jad-130608  0.627
2011 Nelson A, Kolasa K, Fallon K, McMahon L. P4-430: Noradrenergic sympathetic sprouting in human Alzheimer's and the effect of NGF and Aβ on sympathetic sprouting in cholinergically denervated rats Alzheimer's & Dementia. 7: e62-e62. DOI: 10.1016/J.Jalz.2011.09.126  0.593
2010 Smith CC, Vedder LC, Nelson AR, Bredemann TM, McMahon LL. Duration of estrogen deprivation, not chronological age, prevents estrogen's ability to enhance hippocampal synaptic physiology. Proceedings of the National Academy of Sciences of the United States of America. 107: 19543-8. PMID 20974957 DOI: 10.1073/Pnas.1009307107  0.616
2010 Nelson AR, Kolasa K, Smith CC, McMahon LL. P3-350: Sympathetic sprouting stimulates cholinergic function and compensates for deficits in M1 receptor dependent LTD, APP processing, and learning Alzheimer's & Dementia. 6: S554-S554. DOI: 10.1016/J.Jalz.2010.05.1851  0.585
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