Jean-Philippe Loeffler - Publications

Affiliations: 
University of Strasbourg, Strasbourg, Grand Est, France 

69 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Bouscary A, Quessada C, René F, Spedding M, Henriques A, Ngo S, Loeffler JP. Drug repositioning in neurodegeneration: An overview of the use of ambroxol in neurodegenerative diseases. European Journal of Pharmacology. 884: 173446. PMID 32739173 DOI: 10.1016/J.Ejphar.2020.173446  0.348
2017 Henriques A, Croixmarie V, Bouscary A, Mosbach A, Keime C, Boursier-Neyret C, Walter B, Spedding M, Loeffler JP. Sphingolipid Metabolism Is Dysregulated at Transcriptomic and Metabolic Levels in the Spinal Cord of an Animal Model of Amyotrophic Lateral Sclerosis. Frontiers in Molecular Neuroscience. 10: 433. PMID 29354030 DOI: 10.3389/Fnmol.2017.00433  0.316
2017 Henriques A, Huebecker M, Blasco H, Keime C, Andres CR, Corcia P, Priestman DA, Platt FM, Spedding M, Loeffler JP. Inhibition of β-Glucocerebrosidase Activity Preserves Motor Unit Integrity in a Mouse Model of Amyotrophic Lateral Sclerosis. Scientific Reports. 7: 5235. PMID 28701774 DOI: 10.1038/S41598-017-05313-0  0.338
2017 Muller S, Brun S, René F, de Sèze J, Loeffler JP, Jeltsch-David H. Autophagy in neuroinflammatory diseases. Autoimmunity Reviews. 16: 856-874. PMID 28572049 DOI: 10.1016/J.Autrev.2017.05.015  0.36
2016 Vernay A, Therreau L, Blot B, Risson V, Dirrig-Grosch S, Waegaert R, Lequeu T, Sellal F, Schaeffer L, Sadoul R, Loeffler JP, René F. A transgenic mouse expressing CHMP2Bintron5 mutant in neurons develops histological and behavioural features of amyotrophic lateral sclerosis and frontotemporal dementia. Human Molecular Genetics. 25: 3341-3360. PMID 27329763 DOI: 10.1093/Hmg/Ddw182  0.377
2016 Neidl R, Schneider A, Bousiges O, Majchrzak M, Barbelivien A, de Vasconcelos AP, Dorgans K, Doussau F, Loeffler JP, Cassel JC, Boutillier AL. Late-Life Environmental Enrichment Induces Acetylation Events and Nuclear Factor κB-Dependent Regulations in the Hippocampus of Aged Rats Showing Improved Plasticity and Learning. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 4351-61. PMID 27076430 DOI: 10.1523/Jneurosci.3239-15.2016  0.637
2016 Loeffler JP, Picchiarelli G, Dupuis L, Gonzalez De Aguilar JL. The Role of Skeletal Muscle in Amyotrophic Lateral Sclerosis. Brain Pathology (Zurich, Switzerland). 26: 227-36. PMID 26780251 DOI: 10.1111/Bpa.12350  0.329
2015 Henriques A, Croixmarie V, Priestman DA, Rosenbohm A, Dirrig-Grosch S, D'Ambra E, Huebecker M, Hussain G, Boursier-Neyret C, Echaniz-Laguna A, Ludolph AC, Platt FM, Walther B, Spedding M, Loeffler JP, et al. Amyotrophic lateral sclerosis and denervation alter sphingolipids and up-regulate glucosylceramide synthase. Human Molecular Genetics. 24: 7390-405. PMID 26483191 DOI: 10.1093/Hmg/Ddv439  0.335
2015 Palamiuc L, Schlagowski A, Ngo ST, Vernay A, Dirrig-Grosch S, Henriques A, Boutillier AL, Zoll J, Echaniz-Laguna A, Loeffler JP, René F. A metabolic switch toward lipid use in glycolytic muscle is an early pathologic event in a mouse model of amyotrophic lateral sclerosis. Embo Molecular Medicine. 7: 526-46. PMID 25820275 DOI: 10.15252/Emmm.201404433  0.646
2014 Schmitt F, Hussain G, Dupuis L, Loeffler JP, Henriques A. A plural role for lipids in motor neuron diseases: energy, signaling and structure. Frontiers in Cellular Neuroscience. 8: 25. PMID 24600344 DOI: 10.3389/Fncel.2014.00025  0.358
2013 Hussain G, Schmitt F, Henriques A, Lequeu T, Rene F, Bindler F, Dirrig-Grosch S, Oudart H, Palamiuc L, Metz-Boutigue MH, Dupuis L, Marchioni E, Gonzalez De Aguilar JL, Loeffler JP. Systemic down-regulation of delta-9 desaturase promotes muscle oxidative metabolism and accelerates muscle function recovery following nerve injury. Plos One. 8: e64525. PMID 23785402 DOI: 10.1371/Journal.Pone.0064525  0.327
2013 Bousiges O, Neidl R, Majchrzak M, Muller MA, Barbelivien A, Pereira de Vasconcelos A, Schneider A, Loeffler JP, Cassel JC, Boutillier AL. Detection of Histone Acetylation Levels in the Dorsal Hippocampus Reveals Early Tagging on Specific Residues of H2B and H4 Histones in Response to Learning Plos One. 8. PMID 23469244 DOI: 10.1371/Journal.Pone.0057816  0.638
2013 Kabashi E, El Oussini H, Bercier V, Gros-Louis F, Valdmanis PN, McDearmid J, Mejier IA, Dion PA, Dupre N, Hollinger D, Sinniger J, Dirrig-Grosch S, Camu W, Meininger V, Loeffler JP, et al. Investigating the contribution of VAPB/ALS8 loss of function in amyotrophic lateral sclerosis. Human Molecular Genetics. 22: 2350-60. PMID 23446633 DOI: 10.1093/Hmg/Ddt080  0.346
2013 Dentel C, Palamiuc L, Henriques A, Lannes B, Spreux-Varoquaux O, Gutknecht L, René F, Echaniz-Laguna A, Gonzalez de Aguilar JL, Lesch KP, Meininger V, Loeffler JP, Dupuis L. Degeneration of serotonergic neurons in amyotrophic lateral sclerosis: a link to spasticity. Brain : a Journal of Neurology. 136: 483-93. PMID 23114367 DOI: 10.1093/Brain/Aws274  0.389
2012 Audouard E, Schakman O, René F, Huettl RE, Huber AB, Loeffler JP, Gailly P, Clotman F. The Onecut Transcription Factor HNF-6 Regulates in Motor Neurons the Formation of the Neuromuscular Junctions Plos One. 7. PMID 23227180 DOI: 10.1371/Journal.Pone.0050509  0.368
2012 Pradat PF, Dubourg O, de Tapia M, di Scala F, Dupuis L, Lenglet T, Bruneteau G, Salachas F, Lacomblez L, Corvol JC, Demougin P, Primig M, Meininger V, Loeffler JP, Gonzalez de Aguilar JL. Muscle gene expression is a marker of amyotrophic lateral sclerosis severity. Neuro-Degenerative Diseases. 9: 38-52. PMID 21934272 DOI: 10.1159/000329723  0.344
2011 Benosman S, Meng X, Von Grabowiecki Y, Palamiuc L, Hritcu L, Gross I, Mellitzer G, Taya Y, Loeffler JP, Gaiddon C. Complex regulation of p73 isoforms after alteration of amyloid precursor polypeptide (APP) function and DNA damage in neurons. The Journal of Biological Chemistry. 286: 43013-25. PMID 22002055 DOI: 10.1074/Jbc.M111.261271  0.443
2011 Fergani A, Eschbach J, Oudart H, Larmet Y, Schwalenstocker B, Ludolph AC, Loeffler JP, Dupuis L. A mutation in the dynein heavy chain gene compensates for energy deficit of mutant SOD1 mice and increases potentially neuroprotective IGF-1. Molecular Neurodegeneration. 6: 26. PMID 21521523 DOI: 10.1186/1750-1326-6-26  0.339
2011 Dupuis L, Pradat PF, Ludolph AC, Loeffler JP. Energy metabolism in amyotrophic lateral sclerosis The Lancet Neurology. 10: 75-82. PMID 21035400 DOI: 10.1016/S1474-4422(10)70224-6  0.316
2010 Dupuis L, Spreux-Varoquaux O, Bensimon G, Jullien P, Lacomblez L, Salachas F, Bruneteau G, Pradat PF, Loeffler JP, Meininger V. Platelet serotonin level predicts survival in amyotrophic lateral sclerosis. Plos One. 5: e13346. PMID 20967129 DOI: 10.1371/Journal.Pone.0013346  0.361
2010 Bousiges O, Vasconcelos APD, Neidl R, Cosquer B, Herbeaux K, Panteleeva I, Loeffler JP, Cassel JC, Boutillier AL. Spatial memory consolidation is associated with induction of several lysine-acetyltransferase (histone acetyltransferase) expression levels and H2B/H4 acetylation-dependent transcriptional events in the rat hippocampus Neuropsychopharmacology. 35: 2521-2537. PMID 20811339 DOI: 10.1038/Npp.2010.117  0.645
2010 Halter B, Gonzalez de Aguilar JL, Rene F, Petri S, Fricker B, Echaniz-Laguna A, Dupuis L, Larmet Y, Loeffler JP. Oxidative stress in skeletal muscle stimulates early expression of Rad in a mouse model of amyotrophic lateral sclerosis. Free Radical Biology & Medicine. 48: 915-23. PMID 20079427 DOI: 10.1016/J.Freeradbiomed.2010.01.014  0.346
2009 Meng X, Leyva ML, Jenny M, Gross I, Benosman S, Fricker B, Harlepp S, Hébraud P, Boos A, Wlosik P, Bischoff P, Sirlin C, Pfeffer M, Loeffler JP, Gaiddon C. A ruthenium-containing organometallic compound reduces tumor growth through induction of the endoplasmic reticulum stress gene CHOP. Cancer Research. 69: 5458-66. PMID 19549908 DOI: 10.1158/0008-5472.Can-08-4408  0.333
2009 Dupuis L, Gonzalez de Aguilar JL, Echaniz-Laguna A, Eschbach J, Rene F, Oudart H, Halter B, Huze C, Schaeffer L, Bouillaud F, Loeffler JP. Muscle mitochondrial uncoupling dismantles neuromuscular junction and triggers distal degeneration of motor neurons. Plos One. 4: e5390. PMID 19404401 DOI: 10.1371/Journal.Pone.0005390  0.351
2009 Dupuis L, Loeffler JP. Neuromuscular junction destruction during amyotrophic lateral sclerosis: insights from transgenic models Current Opinion in Pharmacology. 9: 341-346. PMID 19386549 DOI: 10.1016/J.Coph.2009.03.007  0.372
2008 Gonzalez de Aguilar JL, Loeffler JP, Boutillier AL. Lesions and genes: on the edge of improved isomorphic models for Alzheimer's disease? Neuro-Degenerative Diseases. 5: 318-20. PMID 18520166 DOI: 10.1159/000135616  0.619
2008 Dupuis L, Pehar M, Cassina P, Rene F, Castellanos R, Rouaux C, Gandelman M, Dimou L, Schwab ME, Loeffler JP, Barbeito L, Gonzalez de Aguilar JL. Nogo receptor antagonizes p75NTR-dependent motor neuron death. Proceedings of the National Academy of Sciences of the United States of America. 105: 740-5. PMID 18182498 DOI: 10.1073/Pnas.0703842105  0.377
2007 Boutillier S, Lannes B, Buée L, Delacourte A, Rouaux C, Mohr M, Bellocq JP, Sellal F, Larmet Y, Boutillier AL, Loeffler JP. Sp3 and sp4 transcription factor levels are increased in brains of patients with Alzheimer's disease. Neuro-Degenerative Diseases. 4: 413-23. PMID 17934324 DOI: 10.1159/000107701  0.682
2007 Panteleeva I, Boutillier S, See V, Spiller DG, Rouaux C, Almouzni G, Bailly D, Maison C, Lai HC, Loeffler JP, Boutillier AL. HP1alpha guides neuronal fate by timing E2F-targeted genes silencing during terminal differentiation. The Embo Journal. 26: 3616-28. PMID 17627279 DOI: 10.1038/Sj.Emboj.7601789  0.69
2007 Rouaux C, Panteleeva I, René F, Gonzalez de Aguilar JL, Echaniz-Laguna A, Dupuis L, Menger Y, Boutillier AL, Loeffler JP. Sodium valproate exerts neuroprotective effects in vivo through CREB-binding protein-dependent mechanisms but does not improve survival in an amyotrophic lateral sclerosis mouse model. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 5535-45. PMID 17522299 DOI: 10.1523/Jneurosci.1139-07.2007  0.678
2007 Fergani A, Oudart H, Gonzalez De Aguilar JL, Fricker B, René F, Hocquette JF, Meininger V, Dupuis L, Loeffler JP. Increased peripheral lipid clearance in an animal model of amyotrophic lateral sclerosis. Journal of Lipid Research. 48: 1571-80. PMID 17438338 DOI: 10.1194/Jlr.M700017-Jlr200  0.342
2007 Pogačić V, Herrling P, Boutillier S, Lannes B, Buée L, Delacourte A, Rouaux C, Mohr M, Bellocq J, Sellal F, Larmet Y, Boutillier A, Loeffler J, Irizarry MC, Yao Y, et al. Contents Vol. 4, 2007 Neurodegenerative Diseases. 4: 491-493. DOI: 10.1159/000109843  0.588
2007 Pogačić V, Herrling P, Boutillier S, Lannes B, Buée L, Delacourte A, Rouaux C, Mohr M, Bellocq J, Sellal F, Larmet Y, Boutillier A, Loeffler J, Irizarry MC, Yao Y, et al. Subject Index Vol. 4, 2007 Neurodegenerative Diseases. 4: 489-490. DOI: 10.1159/000109842  0.585
2006 Koistinen H, Prinjha R, Soden P, Harper A, Banner SJ, Pradat PF, Loeffler JP, Dingwall C. Elevated levels of amyloid precursor protein in muscle of patients with amyotrophic lateral sclerosis and a mouse model of the disease. Muscle & Nerve. 34: 444-50. PMID 16856153 DOI: 10.1002/Mus.20612  0.35
2005 Fergani A, Dupuis L, Jokic N, Larmet Y, de Tapia M, Rene F, Loeffler JP, Gonzalez de Aguilar JL. Reticulons as markers of neurological diseases: focus on amyotrophic lateral sclerosis. Neuro-Degenerative Diseases. 2: 185-94. PMID 16909024 DOI: 10.1159/000089624  0.377
2005 Di Scala F, Dupuis L, Gaiddon C, De Tapia M, Jokic N, Gonzalez de Aguilar JL, Raul JS, Ludes B, Loeffler JP. Tissue specificity and regulation of the N-terminal diversity of reticulon 3. The Biochemical Journal. 385: 125-34. PMID 15350194 DOI: 10.1042/Bj20040458  0.414
2004 Dupuis L, Gonzalez de Aguilar JL, Oudart H, de Tapia M, Barbeito L, Loeffler JP. Mitochondria in amyotrophic lateral sclerosis: a trigger and a target. Neuro-Degenerative Diseases. 1: 245-54. PMID 16908975 DOI: 10.1159/000085063  0.359
2004 Panteleeva I, Rouaux C, Larmet Y, Boutillier S, Loeffler JP, Boutillier AL. HDAC-3 participates in the repression of e2f-dependent gene transcription in primary differentiated neurons. Annals of the New York Academy of Sciences. 1030: 656-60. PMID 15659849 DOI: 10.1196/Annals.1329.076  0.719
2004 Rouaux C, Loeffler JP, Boutillier AL. Targeting CREB-binding protein (CBP) loss of function as a therapeutic strategy in neurological disorders. Biochemical Pharmacology. 68: 1157-64. PMID 15313413 DOI: 10.1016/J.Bcp.2004.05.035  0.688
2004 Dupuis L, Oudart H, René F, Gonzalez de Aguilar JL, Loeffler JP. Evidence for defective energy homeostasis in amyotrophic lateral sclerosis: benefit of a high-energy diet in a transgenic mouse model. Proceedings of the National Academy of Sciences of the United States of America. 101: 11159-64. PMID 15263088 DOI: 10.1073/Pnas.0402026101  0.356
2003 Jokic N, Di Scala F, Dupuis L, Rene F, Muller A, Gonzalez De Aguilar JL, Loeffler JP. Early activation of antioxidant mechanisms in muscle of mutant Cu/Zn-superoxide dismutase-linked amyotrophic lateral sclerosis mice. Annals of the New York Academy of Sciences. 1010: 552-6. PMID 15033789 DOI: 10.1196/Annals.1299.102  0.302
2003 González De Aguilar JL, René F, Dupuis L, Loeffler JP. Neuroendocrinology of neurodegenerative diseases: Insights from transgenic mouse models Neuroendocrinology. 78: 244-252. PMID 14657605 DOI: 10.1159/000074445  0.323
2003 Rouaux C, Jokic N, Mbebi C, Boutillier S, Loeffler JP, Boutillier AL. Critical loss of CBP/p300 histone acetylase activity by caspase-6 during neurodegeneration. The Embo Journal. 22: 6537-49. PMID 14657026 DOI: 10.1093/Emboj/Cdg615  0.711
2003 Dupuis L, di Scala F, Rene F, de Tapia M, Oudart H, Pradat PF, Meininger V, Loeffler JP. Up-regulation of mitochondrial uncoupling protein 3 reveals an early muscular metabolic defect in amyotrophic lateral sclerosis. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 17: 2091-3. PMID 14500553 DOI: 10.1096/Fj.02-1182Fje  0.347
2003 Boutillier AL, Trinh E, Loeffler JP. Selective E2F-dependent gene transcription is controlled by histone deacetylase activity during neuronal apoptosis. Journal of Neurochemistry. 84: 814-28. PMID 12562525 DOI: 10.1046/J.1471-4159.2003.01581.X  0.716
2002 Boutillier AL, Trinh E, Loeffler JP. Constitutive repression of E2F1 transcriptional activity through HDAC proteins is essential for neuronal survival. Annals of the New York Academy of Sciences. 973: 438-42. PMID 12485907 DOI: 10.1111/J.1749-6632.2002.Tb04679.X  0.697
2002 Dupuis L, Gonzalez de Aguilar JL, di Scala F, Rene F, de Tapia M, Pradat PF, Lacomblez L, Seihlan D, Prinjha R, Walsh FS, Meininger V, Loeffler JP. Nogo provides a molecular marker for diagnosis of amyotrophic lateral sclerosis. Neurobiology of Disease. 10: 358-65. PMID 12270696 DOI: 10.1006/Nbdi.2002.0522  0.336
2002 Crochemore C, Michaelidis TM, Fischer D, Loeffler JP, Almeida OF. Enhancement of p53 activity and inhibition of neural cell proliferation by glucocorticoid receptor activation. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 16: 761-70. PMID 12039857 DOI: 10.1096/Fj.01-0577Com  0.336
2002 Mbebi C, Sée V, Mercken L, Pradier L, Müller U, Loeffler JP. Amyloid precursor protein family-induced neuronal death is mediated by impairment of the neuroprotective calcium/calmodulin protein kinase IV-dependent signaling pathway. The Journal of Biological Chemistry. 277: 20979-90. PMID 11877414 DOI: 10.1074/Jbc.M107948200  0.398
2002 Dupuis L, Mbebi C, Gonzalez de Aguilar JL, Rene F, Muller A, de Tapia M, Loeffler JP. Loss of prion protein in a transgenic model of amyotrophic lateral sclerosis. Molecular and Cellular Neurosciences. 19: 216-24. PMID 11860274 DOI: 10.1006/Mcne.2001.1049  0.349
2002 Gaiddon C, Larmet Y, Trinh E, Boutillier A, Sommer B, Loeffler J. Brain‐Derived Neurotrophic Factor Exerts Opposing Effects on β2‐Adrenergic Receptor According to Depolarization Status of Cerebellar Neurons Journal of Neurochemistry. 73: 1467-1476. PMID 10501191 DOI: 10.1046/J.1471-4159.1999.0731467.X  0.669
2002 Muller A, Lutz-Bucher B, Kienlen-Campard P, Koch B, Loeffler J. Continuous Activation of Pituitary Adenylate Cyclase‐Activating Polypeptide Receptors Elicits Antipodal Effects on Cyclic AMP and Inositol Phospholipid Signaling Pathways in CATH.a Cells: Role of Protein Synthesis and Protein Kinases Journal of Neurochemistry. 70: 1431-1440. PMID 9523559 DOI: 10.1046/J.1471-4159.1998.70041431.X  0.348
2001 Aguilar JGd, Girlanda-Junges C, Coowar D, Duportail G, Loeffler J, Luu B. Neurotrophic activity of 2,4,4-trimethyl-3-(15-hydroxypentadecyl)-2-cyclohexen-1-one in cultured central nervous system neurons. Brain Research. 920: 65-73. PMID 11716812 DOI: 10.1016/S0006-8993(01)03007-4  0.351
2001 Sée V, Loeffler J. Oxidative Stress Induces Neuronal Death by Recruiting a Protease and Phosphatase-gated Mechanism Journal of Biological Chemistry. 276: 35049-35059. PMID 11443132 DOI: 10.1074/Jbc.M104988200  0.412
2001 Trinh E, Boutillier AL, Loeffler JP. Regulation of the retinoblastoma-dependent Mdm2 and E2F-1 signaling pathways during neuronal apoptosis. Molecular and Cellular Neurosciences. 17: 342-53. PMID 11178871 DOI: 10.1006/Mcne.2000.0928  0.711
2001 Sée V, Boutillier AL, Bito H, Loeffler JP. Calcium/calmodulin-dependent protein kinase type IV (CaMKIV) inhibits apoptosis induced by potassium deprivation in cerebellar granule neurons. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 15: 134-144. PMID 11149901 DOI: 10.1096/Fj.00-0106Com  0.694
2000 González De Aguilar JL, Gordon JW, René F, De Tapia M, Lutz-Bucher B, Gaiddon C, Loeffler JP. Alteration of the Bcl-x/Bax ratio in a transgenic mouse model of amyotrophic lateral sclerosis: Evidence for the implication of the p53 signaling pathway Neurobiology of Disease. 7: 406-415. PMID 10964611 DOI: 10.1006/Nbdi.2000.0295  0.429
2000 Dupuis L, De Tapia M, René F, Lutz-Bucher B, Gordon JW, Mercken L, Pradier L, Loeffler JP. Differential screening of mutated SOD1 transgenic mice reveals early up-regulation of a fast axonal transport component in spinal motor neurons Neurobiology of Disease. 7: 274-285. PMID 10964600 DOI: 10.1006/Nbdi.2000.0292  0.347
2000 Boutillier AL, Trinh E, Loeffler JP. Caspase-dependent cleavage of the retinoblastoma protein is an early step in neuronal apoptosis. Oncogene. 19: 2171-8. PMID 10822366 DOI: 10.1038/Sj.Onc.1203532  0.686
1999 Sohm F, Gaiddon C, Antoine M, Boutillier AL, Loeffler JP. The retinoblastoma susceptibility gene product/Sp1 signalling pathway is modulated by Ca2+/calmodulin kinases II and IV activity. Oncogene. 18: 2762-9. PMID 10348351 DOI: 10.1038/Sj.Onc.1202634  0.655
1999 Boutillier A, Kienlen‐Campard P, Loeffler J. Depolarization Regulates Cyclin D1 Degradation And Neuronal Apoptosis : A Hypothesis About The Role Of The Ubiquitin/Proteasome Signalling Pathway European Journal of Neuroscience. 11: 441-448. PMID 10051745 DOI: 10.1046/J.1460-9568.1999.00451.X  0.686
1999 Kienlen-Campard P, Boutillier A, Loeffler J. Le neurone : un condamné à mort en sursis permanent ? MéDecine/Sciences. 15: 77. DOI: 10.4267/10608/1201  0.659
1998 René F, Muller A, Jover E, Kieffer B, Koch B, Loeffler J. Melanocortin receptors and δ‐opioid receptor mediate opposite signalling actions of POMC‐derived peptides in CATH.a cells European Journal of Neuroscience. 10: 1885-1894. PMID 9751158 DOI: 10.1046/J.1460-9568.1998.00199.X  0.332
1997 Muller A, Monnier D, Rene F, Larmet Y, Koch B, Loeffler JP. Pituitary adenylate cyclase-activating polypeptide triggers dual transduction signaling in CATH.a cells and transcriptionally activates tyrosine hydroxylase and c-fos expression. Journal of Neurochemistry. 68: 1696-704. PMID 9084443 DOI: 10.1046/J.1471-4159.1997.68041696.X  0.379
1996 René F, Monnier D, Gaiddon C, Félix JM, Loeffler JP. Pituitary adenylate cyclase-activating polypeptide transduces through cAMP/PKA and PKC pathways and stimulates proopiomelanocortin gene transcription in mouse melanotropes. Neuroendocrinology. 64: 2-13. PMID 8811660 DOI: 10.1159/000127091  0.337
1994 Monnier D, Gaiddon C, Boutillier A, Barthel F, Loeffler J. PACAP 27 and 38 stimulate proopiomelanocortin (POMC) and proenkephalin (PENK) gene transcription Regulatory Peptides. 54: 199-200. DOI: 10.1016/0167-0115(94)90459-6  0.645
1994 Gaiddon C, Monnier D, Boutillier A, Loeffler J. Oncogenic Gαs proteins stimulate proopiiomelanocortin (POMC) and proenkephalin (PEnk) gene transcription Regulatory Peptides. 54: 101-102. DOI: 10.1016/0167-0115(94)90409-X  0.655
1992 Bejanin S, Habert E, Berrard S, Edwards JDM, Loeffler J, Mallet J. Promoter elements of the rat choline acetyltransferase gene allowing nerve growth factor inducibility in transfected primary cultured cells. Journal of Neurochemistry. 58: 1580-1583. PMID 1548488 DOI: 10.1111/J.1471-4159.1992.Tb11383.X  0.352
1990 Demeneix BA, Kley N, Loeffler JP. Differentiation to a neuronal phenotype in bovine chromaffin cells is repressed by protein kinase C and is not dependent on c-fos oncoproteins. Dna and Cell Biology. 9: 335-45. PMID 2115338 DOI: 10.1089/Dna.1990.9.335  0.334
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