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Robert Tokhunts, PhD, MD. - Publications

Affiliations: 
1999-2004 Forensic Science John Jay College of Criminal Justice, CUNY, New York, NY, United States 
 2006-2012 Pharmacology and Toxicology Geisel School of Medicine at Dartmouth, Hanover, NH, United States 
 2010-2012 Surgical Oncology University of Miami Miller School of Medicine, Miami, FL, United States 
 2012-2014 Neuroscience Johns Hopkins Neuroscience 
 2014-2018 Medicine Geisel School of Medicine at Dartmouth, Hanover, NH, United States 
Area:
NMDA excitotoxicity, Heme degradation, Hedgehog Signaling
Website:
http://neuroscience.jhu.edu/research/faculty/83
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16 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Vasavda C, Semenza ER, Liew J, Kothari R, Dhindsa RS, Shanmukha S, Lin A, Tokhunts R, Ricco C, Snowman AM, Albacarys L, Pastore F, Ripoli C, Grassi C, Barone E, et al. Biliverdin reductase bridges focal adhesion kinase to Src to modulate synaptic signaling. Science Signaling. 15: eabh3066. PMID 35536885 DOI: 10.1126/scisignal.abh3066  0.753
2020 Rao F, Cha J, Xu J, Xu R, Vandiver MS, Tyagi R, Tokhunts R, Koldobskiy MA, Fu C, Barrow R, Wu M, Fiedler D, Barrow JC, Snyder SH. Inositol Pyrophosphates Mediate the DNA-PK/ATM-p53 Cell Death Pathway by Regulating CK2 Phosphorylation of Tti1/Tel2. Molecular Cell. 79: 702. PMID 32822581 DOI: 10.1016/j.molcel.2020.07.021  0.728
2020 Paul BD, Vasavda C, Kothari R, Malla A, Ricco C, Snowman A, Tokhunts R, Sedlak TW, Snyder S. The role of bilirubin and heme metabolism in neuronal stress signaling The Faseb Journal. 34: 1-1. DOI: 10.1096/fasebj.2020.34.s1.02148  0.743
2019 Vasavda C, Kothari R, Malla AP, Tokhunts R, Lin A, Ji M, Ricco C, Xu R, Saavedra HG, Sbodio JI, Snowman AM, Albacarys L, Hester L, Sedlak TW, Paul BD, et al. Bilirubin Links Heme Metabolism to Neuroprotection by Scavenging Superoxide. Cell Chemical Biology. PMID 31353321 DOI: 10.1016/J.Chembiol.2019.07.006  0.723
2015 Long J, Tokhunts R, Old WM, Houel S, Rodgriguez-Blanco J, Singh S, Schilling N, Capobianco AJ, Ahn NG, Robbins DJ. Identification of a family of fatty-acid-speciated sonic hedgehog proteins, whose members display differential biological properties. Cell Reports. 10: 1280-7. PMID 25732819 DOI: 10.1016/J.Celrep.2015.01.058  0.727
2014 Rao F, Cha J, Xu J, Xu R, Vandiver MS, Tyagi R, Tokhunts R, Koldobskiy MA, Fu C, Barrow R, Wu M, Fiedler D, Barrow JC, Snyder SH. Inositol pyrophosphates mediate the DNA-PK/ATM-p53 cell death pathway by regulating CK2 phosphorylation of Tti1/Tel2. Molecular Cell. 54: 119-32. PMID 24657168 DOI: 10.1016/J.Molcel.2014.02.020  0.725
2013 Rodriguez-Blanco J, Schilling NS, Tokhunts R, Giambelli C, Long J, Liang Fei D, Singh S, Black KE, Wang Z, Galimberti F, Bejarano PA, Elliot S, Glassberg MK, Nguyen DM, Lockwood WW, et al. The hedgehog processing pathway is required for NSCLC growth and survival. Oncogene. 32: 2335-45. PMID 22733134 DOI: 10.1038/Onc.2012.243  0.725
2012 Fei DL, Sanchez-Mejias A, Wang Z, Flaveny C, Long J, Singh S, Rodriguez-Blanco J, Tokhunts R, Giambelli C, Briegel KJ, Schulz WA, Gandolfi AJ, Karagas M, Zimmers TA, Jorda M, et al. Hedgehog signaling regulates bladder cancer growth and tumorigenicity. Cancer Research. 72: 4449-58. PMID 22815529 DOI: 10.1158/0008-5472.Can-11-4123  0.786
2011 Singh S, Wang Z, Liang Fei D, Black KE, Goetz JA, Tokhunts R, Giambelli C, Rodriguez-Blanco J, Long J, Lee E, Briegel KJ, Bejarano PA, Dmitrovsky E, Capobianco AJ, Robbins DJ. Hedgehog-producing cancer cells respond to and require autocrine Hedgehog activity. Cancer Research. 71: 4454-63. PMID 21565978 DOI: 10.1158/0008-5472.Can-10-2313  0.778
2010 Xiao C, Ogle SA, Schumacher MA, Schilling N, Tokhunts RA, Orr-Asman MA, Miller ML, Robbins DJ, Hollande F, Zavros Y. Hedgehog signaling regulates E-cadherin expression for the maintenance of the actin cytoskeleton and tight junctions. American Journal of Physiology. Gastrointestinal and Liver Physiology. 299: G1252-65. PMID 20847300 DOI: 10.1152/Ajpgi.00512.2009  0.737
2010 Tokhunts R, Singh S, Chu T, D'Angelo G, Baubet V, Goetz JA, Huang Z, Yuan Z, Ascano M, Zavros Y, Thérond PP, Kunes S, Dahmane N, Robbins DJ. The full-length unprocessed hedgehog protein is an active signaling molecule. The Journal of Biological Chemistry. 285: 2562-8. PMID 19920144 DOI: 10.1074/Jbc.M109.078626  0.788
2009 Britton M, Lucas MM, Downey SL, Screen M, Pletnev AA, Verdoes M, Tokhunts RA, Amir O, Goddard AL, Pelphrey PM, Wright DL, Overkleeft HS, Kisselev AF. Selective inhibitor of proteasome's caspase-like sites sensitizes cells to specific inhibition of chymotrypsin-like sites. Chemistry & Biology. 16: 1278-89. PMID 20064438 DOI: 10.1016/J.Chembiol.2009.11.015  0.726
2009 Singh S, Tokhunts R, Baubet V, Goetz JA, Huang ZJ, Schilling NS, Black KE, MacKenzie TA, Dahmane N, Robbins DJ. Sonic hedgehog mutations identified in holoprosencephaly patients can act in a dominant negative manner. Human Genetics. 125: 95-103. PMID 19057928 DOI: 10.1007/S00439-008-0599-0  0.727
2005 Rosmarion K, Tokhunts R, Rothchild R. Diels-alder adducts of 3,6-dibromophencyclone with symmetrical 1,4-disubstituted-cis-2-butenes: comparisons with the adduct of phencyclone and N-benzylmaleimide, and one-dimensional and two-dimensional nuclear magnetic resonance studies and ab initio structure calculations. Applied Spectroscopy. 59: 366-75. PMID 15901319  0.708
2004 Tokhunts R, Ramirez O, Rothchild R. NMR Studies of Crowded Diels–Alder Adducts of 3,6‐Dibromophencyclone withN‐(2,6‐Dialkylphenyl)maleimides. Hindered Rotations and Magnetic Anisotropy. Ab Initio Calculations for Optimized Structures of the Precursor Maleimides and Their Adducts with Phencyclone and 3,6‐Dibromophencyclone Spectroscopy Letters. 37: 533-552. DOI: 10.1081/SL-120040189  0.706
2004 Ramirez O, Tokhunts R, Rothchild R. NMR Studies of Crowded Diels–Alder Adducts of Phencyclone withN‐(2,6‐Dialkylphenyl)maleimides. Hindered Rotations and Magnetic Anisotropy Spectroscopy Letters. 37: 421-436. DOI: 10.1081/SL-120039591  0.703
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