| Year |
Citation |
Score |
| 2023 |
Williams JA, Biancucci M, Lessen L, Tian S, Balsaraf A, Chen L, Chesterman C, Maruggi G, Vandepaer S, Huang Y, Mallett CP, Steff AM, Bottomley MJ, Malito E, Wahome N, et al. Structural and computational design of a SARS-CoV-2 spike antigen with improved expression and immunogenicity. Science Advances. 9: eadg0330. PMID 37285422 DOI: 10.1126/sciadv.adg0330 |
0.307 |
|
| 2022 |
Veggi D, Malito E, Lo Surdo P, Pansegrau W, Rippa V, Wahome N, Savino S, Masignani V, Pizza M, Bottomley MJ. Structural characterization of a cross-protective natural chimera of factor H binding protein from meningococcal serogroup B strain NL096. Computational and Structural Biotechnology Journal. 20: 2070-2081. PMID 35601959 DOI: 10.1016/j.csbj.2022.04.011 |
0.395 |
|
| 2021 |
Harshbarger W, Abeyrathne PD, Tian S, Huang Y, Chandramouli S, Bottomley MJ, Malito E. Improved epitope resolution of the prefusion trimer-specific antibody AM14 bound to the RSV F glycoprotein. Mabs. 13: 1955812. PMID 34420474 DOI: 10.1080/19420862.2021.1955812 |
0.324 |
|
| 2020 |
Harshbarger W, Tian S, Wahome N, Balsaraf A, Bhattacharya D, Jiang D, Pandey R, Tungare K, Friedrich K, Mehzabeen N, Biancucci M, Chinchilla-Olszar D, Mallett CP, Huang Y, Wang Z, ... ... Malito E, et al. Convergent structural features of respiratory syncytial virus neutralizing antibodies and plasticity of the site V epitope on prefusion F. Plos Pathogens. 16: e1008943. PMID 33137810 DOI: 10.1371/journal.ppat.1008943 |
0.365 |
|
| 2020 |
McKenna S, Malito E, Rouse SL, Abate F, Bensi G, Chiarot E, Micoli F, Mancini F, Gomes Moriel D, Grandi G, Mossakowska D, Pearson M, Xu Y, Pease J, Sriskandan S, et al. Structure, dynamics and immunogenicity of a catalytically inactive CC chemokine-degrading protease SpyCEP from . Computational and Structural Biotechnology Journal. 18: 650-660. PMID 32257048 DOI: 10.1016/J.Csbj.2020.03.004 |
0.49 |
|
| 2018 |
Liguori A, Dello Iacono L, Maruggi G, Benucci B, Merola M, Lo Surdo P, López-Sagaseta J, Pizza M, Malito E, Bottomley MJ. NadA3 Structures Reveal Undecad Coiled Coils and LOX1 Binding Regions Competed by Meningococcus B Vaccine-Elicited Human Antibodies. Mbio. 9. PMID 30327444 DOI: 10.1128/Mbio.01914-18 |
0.489 |
|
| 2018 |
Maritan M, Veggi D, Cozzi R, Dello Iacono L, Bartolini E, Lo Surdo P, Maruggi G, Spraggon G, Bottomley MJ, Malito E. Structures of NHBA elucidate a broadly conserved epitope identified by a vaccine induced antibody. Plos One. 13: e0201922. PMID 30133484 DOI: 10.1371/journal.pone.0201922 |
0.383 |
|
| 2018 |
Malito E, Chandramouli S, Carfi A. From recognition to execution-the HCMV Pentamer from receptor binding to fusion triggering. Current Opinion in Virology. PMID 29866439 DOI: 10.1016/J.Coviro.2018.05.004 |
0.35 |
|
| 2017 |
Chandramouli S, Malito E, Nguyen T, Luisi K, Donnarumma D, Xing Y, Norais N, Yu D, Carfi A. Structural basis for potent antibody-mediated neutralization of human cytomegalovirus. Science Immunology. 2. PMID 28783665 DOI: 10.1126/Sciimmunol.Aan1457 |
0.47 |
|
| 2017 |
Maritan M, Cozzi R, Lo Surdo P, Veggi D, Bottomley MJ, Malito E. Crystal structures of human Fabs targeting the Bexsero meningococcal vaccine antigen NHBA. Acta Crystallographica. Section F, Structural Biology Communications. 73: 305-314. PMID 28580917 DOI: 10.1107/S2053230X17006021 |
0.499 |
|
| 2017 |
Carboni F, Adamo R, Fabbrini M, De Ricco R, Cattaneo V, Brogioni B, Veggi D, Pinto V, Passalacqua I, Oldrini D, Rappuoli R, Malito E, Margarit IYR, Berti F. Structure of a protective epitope of group B Streptococcus type III capsular polysaccharide. Proceedings of the National Academy of Sciences of the United States of America. PMID 28439022 DOI: 10.1073/Pnas.1701885114 |
0.487 |
|
| 2016 |
Malito E, Lo Surdo P, Veggi D, Santini L, Stefek H, Brunelli B, Luzzi E, Bottomley MJ, Beernink PT, Scarselli M. Neisseria meningitidis factor H-binding protein bound to monoclonal antibody JAR5: implications for antibody synergy. The Biochemical Journal. 473: 4699-4713. PMID 27784765 DOI: 10.1042/Bcj20160806 |
0.357 |
|
| 2016 |
Liguori A, Malito E, Lo Surdo P, Fagnocchi L, Cantini F, Haag AF, Brier S, Pizza M, Delany I, Bottomley MJ. Molecular Basis of Ligand-Dependent Regulation of NadR, the Transcriptional Repressor of Meningococcal Virulence Factor NadA. Plos Pathogens. 12: e1005557. PMID 27105075 DOI: 10.1371/Journal.Ppat.1005557 |
0.411 |
|
| 2016 |
Abate F, Cozzi R, Maritan M, Lo Surdo P, Maione D, Malito E, Bottomley MJ. Crystal structure of FhuD at 1.6 Å resolution: a ferrichrome-binding protein from the animal and human pathogen Staphylococcus pseudintermedius. Acta Crystallographica. Section F, Structural Biology Communications. 72: 214-9. PMID 26919525 DOI: 10.1107/S2053230X16002272 |
0.401 |
|
| 2016 |
López-Sagaseta J, Malito E, Rappuoli R, Bottomley MJ. Self-assembling protein nanoparticles in the design of vaccines. Computational and Structural Biotechnology Journal. 14: 58-68. PMID 26862374 DOI: 10.1016/J.Csbj.2015.11.001 |
0.391 |
|
| 2015 |
Liljeroos L, Malito E, Ferlenghi I, Bottomley MJ. Structural and Computational Biology in the Design of Immunogenic Vaccine Antigens. Journal of Immunology Research. 2015: 156241. PMID 26526043 DOI: 10.1155/2015/156241 |
0.403 |
|
| 2015 |
Malito E, Carfi A, Bottomley MJ. Protein Crystallography in Vaccine Research and Development. International Journal of Molecular Sciences. 16: 13106-40. PMID 26068237 DOI: 10.3390/Ijms160613106 |
0.448 |
|
| 2015 |
Cozzi R, Malito E, Lazzarin M, Nuccitelli A, Castagnetti A, Bottomley MJ, Margarit I, Maione D, Rinaudo CD. Structure and assembly of group B streptococcus pilus 2b backbone protein. Plos One. 10: e0125875. PMID 25942637 DOI: 10.1371/Journal.Pone.0125875 |
0.444 |
|
| 2014 |
Malito E, Biancucci M, Faleri A, Ferlenghi I, Scarselli M, Maruggi G, Lo Surdo P, Veggi D, Liguori A, Santini L, Bertoldi I, Petracca R, Marchi S, Romagnoli G, Cartocci E, et al. Structure of the meningococcal vaccine antigen NadA and epitope mapping of a bactericidal antibody. Proceedings of the National Academy of Sciences of the United States of America. 111: 17128-33. PMID 25404323 DOI: 10.1073/Pnas.1419686111 |
0.471 |
|
| 2014 |
Abate F, Malito E, Cozzi R, Lo Surdo P, Maione D, Bottomley MJ. Apo, Zn2+-bound and Mn2+-bound structures reveal ligand-binding properties of SitA from the pathogen Staphylococcus pseudintermedius. Bioscience Reports. 34: e00154. PMID 25311310 DOI: 10.1042/Bsr20140088 |
0.404 |
|
| 2014 |
Malito E. Structure-based Vaccine Development (Structural Vaccinology) Acta Crystallographica Section a Foundations and Advances. 70: C697-C697. DOI: 10.1107/S2053273314093024 |
0.389 |
|
| 2013 |
Malito E, Rappuoli R. Finding epitopes with computers. Chemistry & Biology. 20: 1205-6. PMID 24210005 DOI: 10.1016/J.Chembiol.2013.10.002 |
0.39 |
|
| 2013 |
Abate F, Malito E, Falugi F, Margarit Y Ros I, Bottomley MJ. Cloning, expression, purification, crystallization and preliminary X-ray diffraction analysis of SpyCEP, a candidate antigen for a vaccine against Streptococcus pyogenes. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 69: 1103-6. PMID 24100558 DOI: 10.1107/S1744309113024871 |
0.418 |
|
| 2013 |
Tontini M, Berti F, Romano MR, Proietti D, Zambonelli C, Bottomley MJ, Gregorio ED, Giudice GD, Rappuoli R, Costantino P, Brogioni G, Balocchi C, Biancucci M, Malito E. Comparison of CRM197, diphtheria toxoid and tetanus toxoid as protein carriers for meningococcal glycoconjugate vaccines. Vaccine. 31: 4827-4833. PMID 23965218 DOI: 10.1016/J.Vaccine.2013.07.078 |
0.364 |
|
| 2013 |
Schluepen C, Malito E, Marongiu A, Schirle M, McWhinnie E, Lo Surdo P, Biancucci M, Falugi F, Nardi-Dei V, Marchi S, Fontana MR, Lombardi B, De Falco MG, Rinaudo CD, Spraggon G, et al. Mining the bacterial unknown proteome: identification and characterization of a novel family of highly conserved protective antigens in Staphylococcus aureus. The Biochemical Journal. 455: 273-84. PMID 23895222 DOI: 10.1042/Bj20130540 |
0.422 |
|
| 2013 |
Malito E, Faleri A, Lo Surdo P, Veggi D, Maruggi G, Grassi E, Cartocci E, Bertoldi I, Genovese A, Santini L, Romagnoli G, Borgogni E, Brier S, Lo Passo C, Domina M, et al. Defining a protective epitope on factor H binding protein, a key meningococcal virulence factor and vaccine antigen. Proceedings of the National Academy of Sciences of the United States of America. 110: 3304-9. PMID 23396847 DOI: 10.1073/Pnas.1222845110 |
0.426 |
|
| 2013 |
Mariotti P, Malito E, Biancucci M, Lo Surdo P, Mishra RP, Nardi-Dei V, Savino S, Nissum M, Spraggon G, Grandi G, Bagnoli F, Bottomley MJ. Structural and functional characterization of the Staphylococcus aureus virulence factor and vaccine candidate FhuD2. The Biochemical Journal. 449: 683-93. PMID 23113737 DOI: 10.1042/Bj20121426 |
0.452 |
|
| 2012 |
D'Urzo N, Malito E, Biancucci M, Bottomley MJ, Maione D, Scarselli M, Martinelli M. The structure of Clostridium difficile toxin A glucosyltransferase domain bound to Mn2+ and UDP provides insights into glucosyltransferase activity and product release. The Febs Journal. 279: 3085-97. PMID 22747490 DOI: 10.1111/J.1742-4658.2012.08688.X |
0.422 |
|
| 2012 |
Malito E, Bursulaya B, Chen C, Lo Surdo P, Picchianti M, Balducci E, Biancucci M, Brock A, Berti F, Bottomley MJ, Nissum M, Costantino P, Rappuoli R, Spraggon G. Structural basis for lack of toxicity of the diphtheria toxin mutant CRM197. Proceedings of the National Academy of Sciences of the United States of America. 109: 5229-34. PMID 22431623 DOI: 10.1073/Pnas.1201964109 |
0.498 |
|
| 2011 |
Scarselli M, Aricò B, Brunelli B, Savino S, Di Marcello F, Palumbo E, Veggi D, Ciucchi L, Cartocci E, Bottomley MJ, Malito E, Lo Surdo P, Comanducci M, Giuliani MM, Cantini F, et al. Rational design of a meningococcal antigen inducing broad protective immunity. Science Translational Medicine. 3: 91ra62. PMID 21753121 DOI: 10.1126/Scitranslmed.3002234 |
0.398 |
|
| 2011 |
Cozzi R, Malito E, Nuccitelli A, D'Onofrio M, Martinelli M, Ferlenghi I, Grandi G, Telford JL, Maione D, Rinaudo CD. Structure analysis and site-directed mutagenesis of defined key residues and motives for pilus-related sortase C1 in group B Streptococcus. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 25: 1874-86. PMID 21357525 DOI: 10.1096/Fj.10-174797 |
0.425 |
|
| 2010 |
Spraggon G, Koesema E, Scarselli M, Malito E, Biagini M, Norais N, Emolo C, Barocchi MA, Giusti F, Hilleringmann M, Rappuoli R, Lesley S, Covacci A, Masignani V, Ferlenghi I. Supramolecular organization of the repetitive backbone unit of the Streptococcus pneumoniae pilus Plos One. 5. PMID 20559564 DOI: 10.1371/Journal.Pone.0010919 |
0.373 |
|
| 2009 |
Bourdeau RW, Malito E, Chenal A, Bishop BL, Musch MW, Villereal ML, Chang EB, Mosser EM, Rest RF, Tang WJ. Cellular functions and X-ray structure of anthrolysin O, a cholesterol-dependent cytolysin secreted by Bacillus anthracis. The Journal of Biological Chemistry. 284: 14645-56. PMID 19307185 DOI: 10.1074/Jbc.M807631200 |
0.371 |
|
| 2008 |
Malito E, Ralat LA, Manolopoulou M, Tsay JL, Wadlington NL, Tang WJ. Molecular bases for the recognition of short peptide substrates and cysteine-directed modifications of human insulin-degrading enzyme. Biochemistry. 47: 12822-34. PMID 18986166 DOI: 10.1021/Bi801192H |
0.418 |
|
| 2008 |
Malito E, Hulse RE, Tang WJ. Amyloid beta-degrading cryptidases: insulin degrading enzyme, presequence peptidase, and neprilysin. Cellular and Molecular Life Sciences : Cmls. 65: 2574-85. PMID 18470479 DOI: 10.1007/S00018-008-8112-4 |
0.336 |
|
| 2008 |
Alfieri A, Malito E, Orru R, Fraaije MW, Mattevi A. Revealing the moonlighting role of NADP in the structure of a flavin-containing monooxygenase. Proceedings of the National Academy of Sciences of the United States of America. 105: 6572-7. PMID 18443301 DOI: 10.1073/Pnas.0800859105 |
0.593 |
|
| 2007 |
Johnson EC, Malito E, Shen Y, Pentelute B, Rich D, Florián J, Tang WJ, Kent SB. Insights from atomic-resolution X-ray structures of chemically synthesized HIV-1 protease in complex with inhibitors. Journal of Molecular Biology. 373: 573-86. PMID 17869270 DOI: 10.1016/J.Jmb.2007.07.054 |
0.35 |
|
| 2007 |
Johnson EC, Malito E, Shen Y, Rich D, Tang WJ, Kent SB. Modular total chemical synthesis of a human immunodeficiency virus type 1 protease. Journal of the American Chemical Society. 129: 11480-90. PMID 17705484 DOI: 10.1021/Ja072870N |
0.341 |
|
| 2007 |
Im H, Manolopoulou M, Malito E, Shen Y, Zhao J, Neant-Fery M, Sun CY, Meredith SC, Sisodia SS, Leissring MA, Tang WJ. Structure of substrate-free human insulin-degrading enzyme (IDE) and biophysical analysis of ATP-induced conformational switch of IDE. The Journal of Biological Chemistry. 282: 25453-63. PMID 17613531 DOI: 10.1074/Jbc.M701590200 |
0.408 |
|
| 2006 |
Malito E, Sekulic N, Too WC, Konrad M, Lavie A. Elucidation of human choline kinase crystal structures in complex with the products ADP or phosphocholine. Journal of Molecular Biology. 364: 136-51. PMID 17007874 DOI: 10.1016/J.Jmb.2006.08.084 |
0.409 |
|
| 2004 |
Malito E, Alfieri A, Fraaije MW, Mattevi A. Crystal structure of a Baeyer-Villiger monooxygenase. Proceedings of the National Academy of Sciences of the United States of America. 101: 13157-62. PMID 15328411 DOI: 10.1073/Pnas.0404538101 |
0.574 |
|
| 2004 |
Malito E, Coda A, Bilyeu KD, Fraaije MW, Mattevi A. Structures of Michaelis and product complexes of plant cytokinin dehydrogenase: implications for flavoenzyme catalysis. Journal of Molecular Biology. 341: 1237-49. PMID 15321719 DOI: 10.1016/J.Jmb.2004.06.083 |
0.554 |
|
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