Gabriel C. Lander - Publications

Affiliations: 
The Scripps Research Institute, California, USA 
Area:
cryo-EM

65 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Basanta B, Chowdhury S, Lander GC, Grotjahn DA. A guided approach for subtomogram averaging of challenging macromolecular assemblies. Journal of Structural Biology: X. 4: 100041. PMID 33319208 DOI: 10.1016/j.yjsbx.2020.100041  0.72
2020 Hirschi M, Lu WT, Santiago-Frangos A, Wilkinson R, Golden SM, Davidson AR, Lander GC, Wiedenheft B. AcrIF9 tethers non-sequence specific dsDNA to the CRISPR RNA-guided surveillance complex. Nature Communications. 11: 2730. PMID 32483187 DOI: 10.1038/s41467-020-16512-1  0.32
2019 Greene ER, Goodall EA, de la Peña AH, Matyskiela ME, Lander GC, Martin A. Specific lid-base contacts in the 26S proteasome control the conformational switching required for substrate degradation. Elife. 8. PMID 31778111 DOI: 10.7554/Elife.49806  0.72
2019 Carragher B, Cheng Y, Frost A, Glaeser RM, Lander GC, Nogales E, Wang HW. Current outcomes when optimizing "standard" sample preparation for single-particle cryo-em. Journal of Microscopy. PMID 31553060 DOI: 10.1111/Jmi.12834  0.72
2019 Grotjahn DA, Lander GC. Setting the dynein motor in motion: new insights from electron tomography. The Journal of Biological Chemistry. PMID 31285262 DOI: 10.1074/jbc.REV119.003095  0.72
2019 Rollins MF, Chowdhury S, Carter J, Golden SM, Miettinen HM, Santiago-Frangos A, Faith D, Lawrence CM, Lander GC, Wiedenheft B. Structure Reveals a Mechanism of CRISPR-RNA-Guided Nuclease Recruitment and Anti-CRISPR Viral Mimicry. Molecular Cell. PMID 30872121 DOI: 10.1016/j.molcel.2019.02.001  0.68
2018 Otomo T, Chowdhury S, Lander GC. The rod-shaped ATG2A-WIPI4 complex tethers membranes in vitro. Contact (Thousand Oaks (Ventura County, Calif.)). 1. PMID 30766969 DOI: 10.1177/2515256418819936  0.68
2018 de la Peña AH, Goodall EA, Gates SN, Lander GC, Martin A. Substrate-engaged 26 proteasome structures reveal mechanisms for ATP-hydrolysis-driven translocation. Science (New York, N.Y.). PMID 30309908 DOI: 10.1126/science.aav0725  0.72
2018 Chowdhury S, Otomo C, Leitner A, Ohashi K, Aebersold R, Lander GC, Otomo T. Insights into autophagosome biogenesis from structural and biochemical analyses of the ATG2A-WIPI4 complex. Proceedings of the National Academy of Sciences of the United States of America. PMID 30185561 DOI: 10.1073/Pnas.1811874115  0.68
2018 Grotjahn DA, Chowdhury S, Xu Y, McKenney RJ, Schroer TA, Lander GC. Author Correction: Cryo-electron tomography reveals that dynactin recruits a team of dyneins for processive motility. Nature Structural & Molecular Biology. PMID 29476122 DOI: 10.1038/S41594-018-0043-7  0.72
2018 Grotjahn DA, Chowdhury S, Xu Y, McKenney RJ, Schroer TA, Lander GC. Cryo-electron tomography reveals that dynactin recruits a team of dyneins for processive motility. Nature Structural & Molecular Biology. PMID 29416113 DOI: 10.1038/S41594-018-0027-7  0.72
2018 Gardner BM, Castanzo DT, Chowdhury S, Stjepanovic G, Stefely MS, Hurley JH, Lander GC, Martin A. The peroxisomal AAA-ATPase Pex1/Pex6 unfolds substrates by processive threading. Nature Communications. 9: 135. PMID 29321502 DOI: 10.1038/S41467-017-02474-4  0.72
2017 Chen KC, Qu S, Chowdhury S, Noxon IC, Schonhoft JD, Plate L, Powers ET, Kelly JW, Lander GC, Wiseman RL. The endoplasmic reticulum HSP40 co-chaperone ERdj3/DNAJB11 assembles and functions as a tetramer. The Embo Journal. PMID 28655754 DOI: 10.15252/Embj.201695616  0.68
2017 Rollins MF, Chowdhury S, Carter J, Golden SM, Wilkinson RA, Bondy-Denomy J, Lander GC, Wiedenheft B. Cas1 and the Csy complex are opposing regulators of Cas2/3 nuclease activity. Proceedings of the National Academy of Sciences of the United States of America. PMID 28438998 DOI: 10.1073/pnas.1616395114  0.68
2017 Chowdhury S, Carter J, Rollins MF, Golden SM, Jackson RN, Hoffmann C, Nosaka L, Bondy-Denomy J, Maxwell KL, Davidson AR, Fischer ER, Lander GC, Wiedenheft B. Structure Reveals Mechanisms of Viral Suppressors that Intercept a CRISPR RNA-Guided Surveillance Complex. Cell. 169: 47-57.e11. PMID 28340349 DOI: 10.1016/j.cell.2017.03.012  0.68
2016 Smirnova IA, Sjöstrand D, Li F, Björck M, Schäfer J, Östbye H, Högbom M, von Ballmoos C, Lander G, Ädelroth P, Brzezinski P. Isolation of yeast complex IV in native lipid nanodiscs. Biochimica Et Biophysica Acta. PMID 27620332 DOI: 10.1016/J.Bbamem.2016.09.004  0.32
2016 Matyskiela ME, Lu G, Ito T, Pagarigan B, Lu CC, Miller K, Fang W, Wang NY, Nguyen D, Houston J, Carmel G, Tran T, Riley M, Nosaka L, Lander GC, et al. A novel cereblon modulator recruits GSPT1 to the CRL4(CRBN) ubiquitin ligase. Nature. PMID 27338790 DOI: 10.1038/Nature18611  0.72
2016 Zubcevic L, Herzik MA, Chung BC, Liu Z, Lander GC, Lee SY. Cryo-electron microscopy structure of the TRPV2 ion channel. Nature Structural & Molecular Biology. PMID 26779611 DOI: 10.1038/Nsmb.3159  0.32
2016 Dambacher CM, Worden EJ, Herzik MA, Martin A, Lander GC. Atomic structure of the 26S proteasome lid reveals the mechanism of deubiquitinase inhibition. Elife. 5. PMID 26744777 DOI: 10.7554/Elife.13027  0.72
2015 Yang TC, Ortiz D, Nosaka L, Lander GC, Catalano CE. Thermodynamic Interrogation of the Assembly of a Viral Genome Packaging Motor Complex. Biophysical Journal. 109: 1663-75. PMID 26488657 DOI: 10.1016/j.bpj.2015.08.037  0.32
2015 Ciferri C, Lander GC, Nogales E. Protein domain mapping by internal labeling and single particle electron microscopy. Journal of Structural Biology. 192: 159-62. PMID 26431894 DOI: 10.1016/J.Jsb.2015.09.016  0.72
2015 Dambacher CM, Lander GC. Site-specific labeling of proteins for electron microscopy. Journal of Structural Biology. 192: 151-8. PMID 26409249 DOI: 10.1016/j.jsb.2015.09.010  0.72
2015 Bashore C, Dambacher CM, Goodall EA, Matyskiela ME, Lander GC, Martin A. Ubp6 deubiquitinase controls conformational dynamics and substrate degradation of the 26S proteasome. Nature Structural & Molecular Biology. 22: 712-9. PMID 26301997 DOI: 10.1038/Nsmb.3075  0.72
2015 McNulty R, Lokareddy RK, Roy A, Yang Y, Lander GC, Heck AJ, Johnson JE, Cingolani G. Architecture of the Complex Formed by Large and Small Terminase Subunits from Bacteriophage P22. Journal of Molecular Biology. 427: 3285-99. PMID 26301600 DOI: 10.1016/J.Jmb.2015.08.013  0.72
2015 Chowdhury S, Ketcham SA, Schroer TA, Lander GC. Structural organization of the dynein-dynactin complex bound to microtubules. Nature Structural & Molecular Biology. 22: 345-7. PMID 25751425 DOI: 10.1038/Nsmb.2996  0.32
2015 Gardner BM, Chowdhury S, Lander GC, Martin A. The Pex1/Pex6 complex is a heterohexameric AAA+ motor with alternating and highly coordinated subunits. Journal of Molecular Biology. 427: 1375-88. PMID 25659908 DOI: 10.1016/J.Jmb.2015.01.019  0.72
2015 Liu T, Sae-Ueng U, Li D, Lander GC, Zuo X, Jönsson B, Rau D, Shefer I, Evilevitch A. Correction: Solid-to-fluid - Like DNA transition in viruses facilitates infection (Proc Natl Acad Sci USA (2014) 111, 41, (14675-14680) DOI: 10.1073/pnas.1321637111) Proceedings of the National Academy of Sciences of the United States of America. 112: E2410. DOI: 10.1073/pnas.1506556112  0.64
2015 Bashore C, Dambacher CM, Goodall EA, Matyskiela ME, Lander GC, Martin A. Ubp6 deubiquitinase controls conformational dynamics and substrate degradation of the 26S proteasome Nature Structural and Molecular Biology. DOI: 10.1038/nsmb.3075  0.72
2014 Liu T, Sae-Ueng U, Li D, Lander GC, Zuo X, Jönsson B, Rau D, Shefer I, Evilevitch A. Solid-to-fluid-like DNA transition in viruses facilitates infection. Proceedings of the National Academy of Sciences of the United States of America. 111: 14675-80. PMID 25271319 DOI: 10.1073/pnas.1321637111  0.64
2014 Alushin GM, Lander GC, Kellogg EH, Zhang R, Baker D, Nogales E. High-resolution microtubule structures reveal the structural transitions in αβ-tubulin upon GTP hydrolysis. Cell. 157: 1117-29. PMID 24855948 DOI: 10.1016/J.Cell.2014.03.053  0.72
2014 Zhao Q, Potter CS, Carragher B, Lander G, Sworen J, Towne V, Abraham D, Duncan P, Washabaugh MW, Sitrin RD. Characterization of virus-like particles in GARDASIL® by cryo transmission electron microscopy. Human Vaccines & Immunotherapeutics. 10: 734-9. PMID 24299977 DOI: 10.4161/hv.27316  0.72
2014 Liu T, Sae-Ueng U, Li D, Lander GC, Zuo X, Jönsson B, Rau D, Shefer I, Evilevitch A, Reiss H. Solid-to-fluid-like DNA transition in viruses facilitates infection Proceedings of the National Academy of Sciences of the United States of America. 111: 14675-14680. DOI: 10.1073/pnas.1321637111  0.72
2013 Matyskiela ME, Lander GC, Martin A. Conformational switching of the 26S proteasome enables substrate degradation. Nature Structural & Molecular Biology. 20: 781-8. PMID 23770819 DOI: 10.1038/Nsmb.2616  0.72
2013 Lander GC, Martin A, Nogales E. The proteasome under the microscope: the regulatory particle in focus. Current Opinion in Structural Biology. 23: 243-51. PMID 23498601 DOI: 10.1016/J.Sbi.2013.02.004  0.72
2013 Lander GC, Johnson JE, Rau DC, Potter CS, Carragher B, Evilevitch A. DNA bending-induced phase transition of encapsidated genome in phage λ. Nucleic Acids Research. 41: 4518-24. PMID 23449219 DOI: 10.1093/Nar/Gkt137  0.72
2012 Ciferri C, Lander GC, Maiolica A, Herzog F, Aebersold R, Nogales E. Molecular architecture of human polycomb repressive complex 2. Elife. 1: e00005. PMID 23110252 DOI: 10.7554/Elife.00005  0.72
2012 Lander GC, Saibil HR, Nogales E. Go hybrid: EM, crystallography, and beyond. Current Opinion in Structural Biology. 22: 627-35. PMID 22835744 DOI: 10.1016/J.Sbi.2012.07.006  0.72
2012 Roy A, Bhardwaj A, Datta P, Lander GC, Cingolani G. Small terminase couples viral DNA binding to genome-packaging ATPase activity. Structure (London, England : 1993). 20: 1403-13. PMID 22771211 DOI: 10.1016/j.str.2012.05.014  0.72
2012 Lander GC, Baudoux AC, Azam F, Potter CS, Carragher B, Johnson JE. Capsomer dynamics and stabilization in the T = 12 marine bacteriophage SIO-2 and its procapsid studied by CryoEM. Structure (London, England : 1993). 20: 498-503. PMID 22405008 DOI: 10.1016/J.Str.2012.01.007  0.72
2012 Lander GC, Estrin E, Matyskiela ME, Bashore C, Nogales E, Martin A. Complete subunit architecture of the proteasome regulatory particle. Nature. 482: 186-91. PMID 22237024 DOI: 10.1038/Nature10774  0.72
2012 Baudoux AC, Hendrix RW, Lander GC, Bailly X, Podell S, Paillard C, Johnson JE, Potter CS, Carragher B, Azam F. Genomic and functional analysis of Vibrio phage SIO-2 reveals novel insights into ecology and evolution of marine siphoviruses. Environmental Microbiology. 14: 2071-86. PMID 22225728 DOI: 10.1111/J.1462-2920.2011.02685.X  0.72
2011 Wiedenheft B, Lander GC, Zhou K, Jore MM, Brouns SJ, van der Oost J, Doudna JA, Nogales E. Structures of the RNA-guided surveillance complex from a bacterial immune system. Nature. 477: 486-9. PMID 21938068 DOI: 10.1038/Nature10402  0.72
2011 Tang J, Lander GC, Olia AS, Olia A, Li R, Casjens S, Prevelige P, Cingolani G, Baker TS, Johnson JE. Peering down the barrel of a bacteriophage portal: the genome packaging and release valve in p22. Structure (London, England : 1993). 19: 496-502. PMID 21439834 DOI: 10.1016/J.Str.2011.02.010  0.72
2011 Hornung P, Maier M, Alushin GM, Lander GC, Nogales E, Westermann S. Molecular architecture and connectivity of the budding yeast Mtw1 kinetochore complex. Journal of Molecular Biology. 405: 548-59. PMID 21075115 DOI: 10.1016/J.Jmb.2010.11.012  0.72
2010 Matsui T, Lander GC, Khayat R, Johnson JE. Subunits fold at position-dependent rates during maturation of a eukaryotic RNA virus. Proceedings of the National Academy of Sciences of the United States of America. 107: 14111-5. PMID 20660783 DOI: 10.1073/Pnas.1004221107  0.72
2010 Khayat R, Lander GC, Johnson JE. An automated procedure for detecting protein folds from sub-nanometer resolution electron density. Journal of Structural Biology. 170: 513-21. PMID 20026407 DOI: 10.1016/J.Jsb.2009.12.014  0.72
2010 Voss NR, Lyumkis D, Cheng A, Lau PW, Mulder A, Lander GC, Brignole EJ, Fellmann D, Irving C, Jacovetty EL, Leung A, Pulokas J, Quispe JD, Winkler H, Yoshioka C, et al. A toolbox for ab initio 3-D reconstructions in single-particle electron microscopy. Journal of Structural Biology. 169: 389-98. PMID 20018246 DOI: 10.1016/j.jsb.2009.12.005  0.72
2009 Lander GC, Khayat R, Li R, Prevelige PE, Potter CS, Carragher B, Johnson JE. The P22 tail machine at subnanometer resolution reveals the architecture of an infection conduit. Structure (London, England : 1993). 17: 789-99. PMID 19523897 DOI: 10.1016/J.Str.2009.04.006  0.72
2009 Ambrose RL, Lander GC, Maaty WS, Bothner B, Johnson JE, Johnson KN. Drosophila A virus is an unusual RNA virus with a T=3 icosahedral core and permuted RNA-dependent RNA polymerase. The Journal of General Virology. 90: 2191-200. PMID 19474243 DOI: 10.1099/Vir.0.012104-0  0.72
2009 Prust CJ, Doerschuk PC, Lander GC, Johnson JE. Ab initio maximum likelihood reconstruction from cryo electron microscopy images of an infectious virion of the tailed bacteriophage P22 and maximum likelihood versions of Fourier Shell Correlation appropriate for measuring resolution of spherical or cylindrical objects. Journal of Structural Biology. 167: 185-99. PMID 19457456 DOI: 10.1016/J.Jsb.2009.04.013  0.72
2009 Lander GC, Stagg SM, Voss NR, Cheng A, Fellmann D, Pulokas J, Yoshioka C, Irving C, Mulder A, Lau PW, Lyumkis D, Potter CS, Carragher B. Appion: an integrated, database-driven pipeline to facilitate EM image processing. Journal of Structural Biology. 166: 95-102. PMID 19263523 DOI: 10.1016/J.Jsb.2009.01.002  0.72
2009 Matsui T, Lander G, Johnson JE. Characterization of large conformational changes and autoproteolysis in the maturation of a T=4 virus capsid. Journal of Virology. 83: 1126-34. PMID 18987141 DOI: 10.1128/Jvi.01859-08  0.64
2009 Carrillo-Tripp M, Shepherd CM, Borelli IA, Venkataraman S, Lander G, Natarajan P, Johnson JE, Brooks CL, Reddy VS. VIPERdb2: an enhanced and web API enabled relational database for structural virology. Nucleic Acids Research. 37: D436-42. PMID 18981051 DOI: 10.1093/Nar/Gkn840  0.72
2008 Lander GC, Evilevitch A, Jeembaeva M, Potter CS, Carragher B, Johnson JE. Bacteriophage lambda stabilization by auxiliary protein gpD: timing, location, and mechanism of attachment determined by cryo-EM. Structure (London, England : 1993). 16: 1399-406. PMID 18786402 DOI: 10.1016/J.Str.2008.05.016  0.72
2008 Nemecek D, Lander GC, Johnson JE, Casjens SR, Thomas GJ. Assembly architecture and DNA binding of the bacteriophage P22 terminase small subunit. Journal of Molecular Biology. 383: 494-501. PMID 18775728 DOI: 10.1016/J.Jmb.2008.08.050  0.72
2008 Stagg SM, Lander GC, Quispe J, Voss NR, Cheng A, Bradlow H, Bradlow S, Carragher B, Potter CS. A test-bed for optimizing high-resolution single particle reconstructions. Journal of Structural Biology. 163: 29-39. PMID 18534866 DOI: 10.1016/J.Jsb.2008.04.005  0.72
2008 Prasuhn DE, Kuzelka J, Strable E, Udit AK, Cho SH, Lander GC, Quispe JD, Diers JR, Bocian DF, Potter C, Carragher B, Finn MG. Polyvalent display of heme on hepatitis B virus capsid protein through coordination to hexahistidine tags. Chemistry & Biology. 15: 513-9. PMID 18482703 DOI: 10.1016/J.Chembiol.2008.03.018  0.72
2008 Strable E, Prasuhn DE, Udit AK, Brown S, Link AJ, Ngo JT, Lander G, Quispe J, Potter CS, Carragher B, Tirrell DA, Finn MG. Unnatural amino acid incorporation into virus-like particles. Bioconjugate Chemistry. 19: 866-75. PMID 18318461 DOI: 10.1021/Bc700390R  0.72
2008 Kang S, Lander GC, Johnson JE, Prevelige PE. Development of bacteriophage p22 as a platform for molecular display: genetic and chemical modifications of the procapsid exterior surface. Chembiochem : a European Journal of Chemical Biology. 9: 514-8. PMID 18213564 DOI: 10.1002/Cbic.200700555  0.72
2007 Poliakov A, van Duijn E, Lander G, Fu CY, Johnson JE, Prevelige PE, Heck AJ. Macromolecular mass spectrometry and electron microscopy as complementary tools for investigation of the heterogeneity of bacteriophage portal assemblies. Journal of Structural Biology. 157: 371-83. PMID 17064935 DOI: 10.1016/J.Jsb.2006.09.003  0.72
2006 Gan L, Speir JA, Conway JF, Lander G, Cheng N, Firek BA, Hendrix RW, Duda RL, Liljas L, Johnson JE. Capsid conformational sampling in HK97 maturation visualized by X-ray crystallography and cryo-EM. Structure (London, England : 1993). 14: 1655-65. PMID 17098191 DOI: 10.1016/J.Str.2006.09.006  0.72
2006 Stagg SM, Lander GC, Pulokas J, Fellmann D, Cheng A, Quispe JD, Mallick SP, Avila RM, Carragher B, Potter CS. Automated cryoEM data acquisition and analysis of 284742 particles of GroEL. Journal of Structural Biology. 155: 470-81. PMID 16762565 DOI: 10.1016/J.Jsb.2006.04.005  0.72
2006 Lander GC, Tang L, Casjens SR, Gilcrease EB, Prevelige P, Poliakov A, Potter CS, Carragher B, Johnson JE. The structure of an infectious P22 virion shows the signal for headful DNA packaging. Science (New York, N.Y.). 312: 1791-5. PMID 16709746 DOI: 10.1126/Science.1127981  0.72
2006 Shepherd CM, Borelli IA, Lander G, Natarajan P, Siddavanahalli V, Bajaj C, Johnson JE, Brooks CL, Reddy VS. VIPERdb: a relational database for structural virology. Nucleic Acids Research. 34: D386-9. PMID 16381893 DOI: 10.1093/Nar/Gkj032  0.72
2005 Natarajan P, Lander GC, Shepherd CM, Reddy VS, Brooks CL, Johnson JE. Exploring icosahedral virus structures with VIPER. Nature Reviews. Microbiology. 3: 809-17. PMID 16205712 DOI: 10.1038/Nrmicro1283  0.72
Show low-probability matches.