Valeriya Khurdayan, Ph. D. - Related publications

Affiliations: 
Boehringer Ingelheim 
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50 most relevant papers in past 60 days:
Year Citation  Score
2021 Barbaro JM, Cuervo AM, Berman JW. HIV Increases the Inhibitory Impact of Morphine and Antiretrovirals on Autophagy in Primary Human Macrophages: Contributions to Neuropathogenesis. Cells. 10. PMID 34571832 DOI: 10.3390/cells10092183   
2021 de Armas LR, Gavegnano C, Pallikkuth S, Rinaldi S, Pan L, Battivelli E, Verdin E, Younis RT, Pahwa R, Williams SL, Schinazi RF, Pahwa S. The Effect of JAK1/2 Inhibitors on HIV Reservoir Using Primary Lymphoid Cell Model of HIV Latency. Frontiers in Immunology. 12: 720697. PMID 34531866 DOI: 10.3389/fimmu.2021.720697   
2021 Jia X, Shao Q, Chaudhry AR, Kinlock BL, Izban MG, Zhang HY, Villalta F, Hildreth JEK, Liu B. Medroxyprogesterone Acetate (MPA) Enhances HIV-1 Accumulation and Release in Primary Cervical Epithelial Cells by Inhibiting Lysosomal Activity. Pathogens (Basel, Switzerland). 10. PMID 34578224 DOI: 10.3390/pathogens10091192   
2021 Kim H, Zhang W, Hwang J, An EK, Choi YK, Moon E, Loznik M, Huh YH, Herrmann A, Kwak M, Jin JO. Carrier-free micellar CpG interacting with cell membrane for enhanced immunological treatment of HIV-1. Biomaterials. 277: 121081. PMID 34481291 DOI: 10.1016/j.biomaterials.2021.121081   
2021 Bricker KM, Chahroudi A, Mavigner M. New Latency Reversing Agents for HIV-1 Cure: Insights from Nonhuman Primate Models. Viruses. 13. PMID 34452425 DOI: 10.3390/v13081560   
2021 Ratnapriya S, Harris M, Chov A, Herbert ZT, Vrbanac V, Deruaz M, Achuthan V, Engelman AN, Sodroski J, Herschhorn A. Intra- and extra-cellular environments contribute to the fate of HIV-1 infection. Cell Reports. 36: 109622. PMID 34469717 DOI: 10.1016/j.celrep.2021.109622   
2021 Jacob RA, Edgar CR, Prévost J, Trothen SM, Lurie A, Mumby MJ, Galbraith A, Kirchhoff F, Haeryfar SMM, Finzi A, Dikeakos JD. The HIV-1 accessory protein Nef increases surface expression of the checkpoint receptor Tim-3 in infected CD4 T cells. The Journal of Biological Chemistry. 297: 101042. PMID 34358561 DOI: 10.1016/j.jbc.2021.101042   
2021 Campbell GR, Zhuang J, Zhang G, Landa I, Kubiatowicz LJ, Dehaini D, Fang RH, Zhang L, Spector SA. CD4+ T cell-mimicking nanoparticles encapsulating DIABLO/SMAC mimetics broadly neutralize HIV-1 and selectively kill HIV-1-infected cells. Theranostics. 11: 9009-9021. PMID 34522224 DOI: 10.7150/thno.59728   
2021 Lai M, Maori E, Quaranta P, Matteoli G, Maggi F, Sgarbanti M, Crucitta S, Pacini S, Turriziani O, Antonelli G, Heeney JL, Freer G, Pistello M. CRISPR/Cas9 ablation of integrated HIV-1 accumulates proviral DNA circles with reformed LTRs. Journal of Virology. JVI0135821. PMID 34549986 DOI: 10.1128/JVI.01358-21   
2021 Malik S, Valdebenito S, D'Amico D, Prideaux B, Eugenin EA. HIV infection of astrocytes compromises inter-organelle interactions and inositol phosphate metabolism: a potential mechanism of bystander damage and viral reservoir survival. Progress in Neurobiology. 102157. PMID 34455020 DOI: 10.1016/j.pneurobio.2021.102157   
2021 Khoury G, Kulpa DA, Parsons MS. Potential Utility of Natural Killer Cells for Eliminating Cells Harboring Reactivated Latent HIV-1 Following the Removal of CD8 T Cell-Mediated Pro-Latency Effect(s). Viruses. 13. PMID 34452317 DOI: 10.3390/v13081451   
2021 Niu F, Liao K, Hu G, Moidunny S, Roy S, Buch S. HIV Tat-Mediated Induction of Monocyte Transmigration Across the Blood-Brain Barrier: Role of Chemokine Receptor CXCR3. Frontiers in Cell and Developmental Biology. 9: 724970. PMID 34527676 DOI: 10.3389/fcell.2021.724970   
2021 Fattakhov N, Torices S, Stangis M, Park M, Toborek M. Synergistic Impairment of the Neurovascular Unit by HIV-1 Infection and Methamphetamine Use: Implications for HIV-1-Associated Neurocognitive Disorders. Viruses. 13. PMID 34578464 DOI: 10.3390/v13091883   
2021 Card CM, Abrenica B, McKinnon LR, Ball TB, Su RC. Endothelial cells promote productive HIV infection of resting CD4+ T cells by an integrin-mediated cell adhesion-dependent mechanism. Aids Research and Human Retroviruses. PMID 34465136 DOI: 10.1089/AID.2021.0034   
2021 Collins DR, Urbach JM, Racenet ZJ, Arshad U, Power KA, Newman RM, Mylvaganam GH, Ly NL, Lian X, Rull A, Rassadkina Y, Yanez AG, Peluso MJ, Deeks SG, Vidal F, et al. Functional impairment of HIV-specific CD8 T cells precedes aborted spontaneous control of viremia. Immunity. PMID 34496223 DOI: 10.1016/j.immuni.2021.08.007   
2021 Govender Y, Shalekoff S, Ebrahim O, Waja Z, Chaisson RE, Martinson N, Tiemessen CT. Systemic DPP4/CD26 is associated with natural HIV-1 control: Implications for COVID-19 susceptibility. Clinical Immunology (Orlando, Fla.). 230: 108824. PMID 34391936 DOI: 10.1016/j.clim.2021.108824   
2021 Zhao X, Zhao Y, Du J, Gao P, Zhao K. The Interplay Among HIV, LINE-1, and the Interferon Signaling System. Frontiers in Immunology. 12: 732775. PMID 34566998 DOI: 10.3389/fimmu.2021.732775   
2021 Su H, Sravanam S, Sillman B, Waight E, Makarov E, Mathews S, Poluektova LY, Gorantla S, Gendelman HE, Dash PK. Recovery of Latent HIV-1 from Brain Tissue by Adoptive Cell Transfer in Virally Suppressed Humanized Mice. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. PMID 34528173 DOI: 10.1007/s11481-021-10011-w   
2021 Naicker T, Govender N, Abel T, Naidoo N, Moodley M, Pillay Y, Singh S, Khaliq OP, Moodley J. HIV Associated Preeclampsia: A Multifactorial Appraisal. International Journal of Molecular Sciences. 22. PMID 34502066 DOI: 10.3390/ijms22179157   
2021 Lustig G, Cele S, Karim F, Derache A, Ngoepe A, Khan K, Gosnell BI, Moosa MS, Ntshuba N, Marais S, Jeena PM, Govender K, Adamson J, Kløverpris H, Gupta RK, et al. T cell derived HIV-1 is present in the CSF in the face of suppressive antiretroviral therapy. Plos Pathogens. 17: e1009871. PMID 34555123 DOI: 10.1371/journal.ppat.1009871   
2021 Chen Q, Wu C, Zhu J, Li E, Xu Z. Therapeutic potential of indole derivatives as anti-HIV agents: A mini-review. Current Topics in Medicinal Chemistry. PMID 34636313 DOI: 10.2174/1568026621666211012111901   
2021 Lee TJ, Vazquez JA, Rao ASRS. Mathematical modeling of impact of eCD4-Ig molecule in control and management of HIV within a host. Mathematical Biosciences and Engineering : Mbe. 18: 6887-6906. PMID 34517562 DOI: 10.3934/mbe.2021342   
2021 Stephenson KE, Julg B, Tan CS, Zash R, Walsh SR, Rolle CP, Monczor AN, Lupo S, Gelderblom HC, Ansel JL, Kanjilal DG, Maxfield LF, Nkolola J, Borducchi EN, Abbink P, et al. Safety, pharmacokinetics and antiviral activity of PGT121, a broadly neutralizing monoclonal antibody against HIV-1: a randomized, placebo-controlled, phase 1 clinical trial. Nature Medicine. PMID 34621054 DOI: 10.1038/s41591-021-01509-0   
2021 Zhou CL, Huang YF, Li YB, Liang TZ, Zheng TY, Chen P, Wu ZY, Lai FY, Liu SW, Xi BM, Li L. A new small-molecule compound, Q308, silences latent HIV-1 provirus by suppressing Tat- and FACT-mediated transcription. Antimicrobial Agents and Chemotherapy. AAC0047021. PMID 34491808 DOI: 10.1128/AAC.00470-21   
2021 Gornalusse GG, Vojtech LN, Levy CN, Hughes SM, Kim Y, Valdez R, Pandey U, Ochsenbauer C, Astronomo R, McElrath J, Hladik F. Buprenorphine Increases HIV-1 Infection In Vitro but Does Not Reactivate HIV-1 from Latency. Viruses. 13. PMID 34452338 DOI: 10.3390/v13081472   
2021 Breton Y, Barat C, Tremblay MJ. The balance between p53 isoforms modulates the efficiency of HIV-1 infection in macrophages. Journal of Virology. JVI0118821. PMID 34379507 DOI: 10.1128/JVI.01188-21   
2021 Yang X, Huang T, Wang T, Gao H, Zhang H, Peng W, Zhao J, Hu S, Lu P, Hong Z, Li B, Deng K. MAT2A-Mediated S-Adenosylmethionine Level in CD4 T Cells Regulates HIV-1 Latent Infection. Frontiers in Immunology. 12: 745784. PMID 34616406 DOI: 10.3389/fimmu.2021.745784   
2021 Khalid K, Padda J, Wijeratne Fernando R, Mehta KA, Almanie AH, Al Hennawi H, Padda S, Cooper AC, Jean-Charles G. Stem Cell Therapy and Its Significance in HIV Infection. Cureus. 13: e17507. PMID 34595076 DOI: 10.7759/cureus.17507   
2021 Relaño-Rodríguez I, Espinar-Buitrago MS, Martín-Cañadilla V, Gómez-Ramírez R, Muñoz-Fernández MÁ. G2-S16 Polyanionic Carbosilane Dendrimer Can Reduce HIV-1 Reservoir Formation by Inhibiting Macrophage Cell to Cell Transmission. International Journal of Molecular Sciences. 22. PMID 34445073 DOI: 10.3390/ijms22168366   
2021 Dzakah EE, Zhao J, Wang L, Rashid F, Xu R, Yang L, Wan Z, Huang L, Wang H, Chen S, Ke W, Kyei F, Deng K, Tang S. Chlamydia trachomatis stimulation enhances HIV-1 susceptibility via the modulation of a member of the macrophage inflammatory proteins. The Journal of Investigative Dermatology. PMID 34662561 DOI: 10.1016/j.jid.2021.09.020   
2021 Bhaskaran N, Schneider E, Faddoul F, Paes da Silva A, Asaad R, Talla A, Greenspan N, Levine AD, McDonald D, Karn J, Lederman MM, Pandiyan P. Oral immune dysfunction is associated with the expansion of FOXP3PD-1Amphiregulin T cells during HIV infection. Nature Communications. 12: 5143. PMID 34446704 DOI: 10.1038/s41467-021-25340-w   
2021 Wang Z, Yin X, Ma M, Ge H, Lang B, Sun H, He S, Fu Y, Sun Y, Yu X, Zhang Z, Cui H, Han X, Xu J, Ding H, et al. IP-10 Promotes Latent HIV Infection in Resting Memory CD4 T Cells LIMK-Cofilin Pathway. Frontiers in Immunology. 12: 656663. PMID 34447368 DOI: 10.3389/fimmu.2021.656663   
2021 Pasternak AO, Vroom J, Kootstra NA, Wit FW, de Bruin M, De Francesco D, Bakker M, Sabin CA, Winston A, Prins JM, Reiss P, Berkhout B, . Non-nucleoside reverse transcriptase inhibitor-based combination antiretroviral therapy is associated with lower cell-associated HIV RNA and DNA levels as compared with therapy based on protease inhibitors. Elife. 10. PMID 34387543 DOI: 10.7554/eLife.68174   
2021 Ekabe CJ, Clinton NA, Kehbila J, Franck NC. The Role of Inflammasome Activation in Early HIV Infection. Journal of Immunology Research. 2021: 1487287. PMID 34595244 DOI: 10.1155/2021/1487287   
2021 Peterson CW. HIV-specific CAR T cells return to the clinic. The Journal of Clinical Investigation. 131. PMID 34596054 DOI: 10.1172/JCI153204   
2021 Londhe R, Kulkarni S. HTLV-2 Encoded Antisense Protein APH-2 Suppresses HIV-1 Replication. Viruses. 13. PMID 34452297 DOI: 10.3390/v13081432   
2021 Rahman AN, Liu J, Mujib S, Kidane S, Ali A, Szep S, Han C, Bonner P, Parsons M, Benko E, Kovacs C, Yue FY, Ostrowski M. Elevated glycolysis imparts functional ability to CD8 T cells in HIV infection. Life Science Alliance. 4. PMID 34548381 DOI: 10.26508/lsa.202101081   
2021 Shrivastava S, Ray RM, Holguin L, Echavarria L, Grepo N, Scott TA, Burnett J, Morris KV. Exosome-mediated stable epigenetic repression of HIV-1. Nature Communications. 12: 5541. PMID 34545097 DOI: 10.1038/s41467-021-25839-2   
2021 Bandarra S, Miyagi E, Ribeiro AC, Gonçalves J, Strebel K, Barahona I. APOBEC3B potently restricts HIV-2 but not HIV-1 in a Vif-dependent manner. Journal of Virology. JVI0117021. PMID 34523960 DOI: 10.1128/JVI.01170-21   
2021 Martínez-Montesinos Y, Kourí-Cordellá V, Pérez-Santos L, Han R, Pintos-Saavedra Y, Alemán-Campos Y, Soto-Brito Y, Baños-Morales Y, Caturla-Fernández Y. Subtype-Dependent Co-receptor Tropism in Cuban HIV-1-Infected Patients: Implications for Maraviroc Treatment. Medicc Review. 23: 29-36. PMID 34516534 DOI: 10.37757/MR2021.V23.N3.6   
2021 Kuse N, Murakoshi H, Akahoshi T, Chikata T, James KL, Gatanaga H, Rowland-Jones SL, Oka S, Takiguchi M. Collaboration of a detrimental HLA-B*35:01 allele with HLA-A*24:02 in co-evolution of HIV-1 with T-cells leading to poorer clinical outcomes. Journal of Virology. JVI0125921. PMID 34523962 DOI: 10.1128/JVI.01259-21   
2021 Barbour AJ, Nass SR, Hahn YK, Hauser KF, Knapp PE. Restoration of KCC2 Membrane Localization in Striatal Dopamine D2 Receptor-Expressing Medium Spiny Neurons Rescues Locomotor Deficits in HIV Tat-Transgenic Mice. Asn Neuro. 13: 17590914211022089. PMID 34445881 DOI: 10.1177/17590914211022089   
2021 League AF, Gorman BL, Hermes DJ, Johnson CT, Jacobs IR, Yadav-Samudrala BJ, Poklis JL, Niphakis MJ, Cravatt BF, Lichtman AH, Ignatowska-Jankowska BM, Fitting S. Monoacylglycerol Lipase Inhibitor MJN110 Reduces Neuronal Hyperexcitability, Restores Dendritic Arborization Complexity, and Regulates Reward-Related Behavior in Presence of HIV-1 Tat. Frontiers in Neurology. 12: 651272. PMID 34484091 DOI: 10.3389/fneur.2021.651272   
2021 Yero A, Shi T, Farnos O, Routy JP, Tremblay C, Durand M, Tsoukas C, Costiniuk CT, Jenabian MA. Dynamics and epigenetic signature of regulatory T-cells following antiretroviral therapy initiation in acute HIV infection. Ebiomedicine. 71: 103570. PMID 34500304 DOI: 10.1016/j.ebiom.2021.103570   
2021 Kurle S, Kandaswami S, Gadhe S, Patil A, Sarkar R, Mehta S, Gangakhedkar R, Arumugam V, Chawla U. HIV-1 Drug Resistance among treatment naïve Transgenders from India. Aids Research and Human Retroviruses. PMID 34652967 DOI: 10.1089/AID.2021.0157   
2021 Morcilla V, Bacchus-Souffan C, Fisher K, Horsburgh BA, Hiener B, Wang XQ, Schlub TE, Fitch M, Hoh R, Hecht FM, Martin JN, Deeks SG, Hellerstein MK, McCune JM, Hunt PW, et al. HIV-1 Genomes Are Enriched in Memory CD4 T-Cells with Short Half-Lives. Mbio. e0244721. PMID 34544282 DOI: 10.1128/mBio.02447-21   
2021 Jiang Y, Chai L, Wang H, Shen X, Fasae MB, Jiao J, Yu Y, Ju J, Liu B, Bai Y. HIV Tat Protein Induces Myocardial Fibrosis Through TGF-β1-CTGF Signaling Cascade: A Potential Mechanism of HIV Infection-Related Cardiac Manifestations. Cardiovascular Toxicology. PMID 34519946 DOI: 10.1007/s12012-021-09687-6   
2021 Li S, Su B, He QS, Wu H, Zhang T. Alterations in the oral microbiome in HIV infection: causes, effects and potential interventions. Chinese Medical Journal. PMID 34670249 DOI: 10.1097/CM9.0000000000001825   
2021 Monteiro A, Yu KOA, Hicar MD. Peptide-based Fusion Inhibitors for Preventing the Six-helix Bundle Formation of Class I Fusion Proteins: HIV and Beyond. Current Hiv Research. PMID 34503415 DOI: 10.2174/1570162X19666210908115231   
2021 Bektaş E, Sahin H, Beldüz AO, Güler Hİ. HIV-1-RT inhibition activity of Satureja spicigera (C.KOCH) BOISS. Aqueous extract and docking studies of phenolic compounds identified by RP-HPLC-DAD. Journal of Food Biochemistry. e13921. PMID 34477237 DOI: 10.1111/jfbc.13921