Jeffrey M. Zigman, M.D., Ph.D. - Publications

Affiliations: 
University of Texas Southwestern Medical Center, Dallas, TX, United States 
Area:
Gut-brain control of eating behavior

88 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Mani BK, Shankar K, Zigman JM. Ghrelin's relationship to blood glucose. Endocrinology. PMID 30874792 DOI: 10.1210/en.2019-00074  0.52
2019 Gupta D, Chuang JC, Mani BK, Shankar K, Rodriguez JA, Osborne-Lawrence S, Metzger NP, Zigman JM. β1-adrenergic receptors mediate plasma acyl-ghrelin elevation and depressive-like behavior induced by chronic psychosocial stress. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 30758330 DOI: 10.1038/s41386-019-0334-7  0.76
2018 Rodriguez JA, Bruggeman EC, Mani BK, Osborne-Lawrence S, Lord CC, Roseman H, Viroslav HL, Vijayaraghavan P, Metzger NP, Gupta D, Shankar K, Pietra C, Liu C, Zigman JM. Ghrelin Receptor Agonist Rescues Excess Neonatal Mortality in a Prader-Willi Syndrome Mouse Model. Endocrinology. PMID 30380028 DOI: 10.1210/en.2018-00801  0.68
2018 Cornejo MP, De Francesco PN, García Romero G, Portiansky EL, Zigman JM, Reynaldo M, Perello M. Ghrelin receptor signaling targets segregated clusters of neurons within the nucleus of the solitary tract. Brain Structure & Function. PMID 29761230 DOI: 10.1007/s00429-018-1682-5  0.68
2018 Mani BK, Castorena CM, Osborne-Lawrence S, Vijayaraghavan P, Metzger NP, Elmquist JK, Zigman JM. Ghrelin mediates exercise endurance and the feeding response post-exercise. Molecular Metabolism. PMID 29396372 DOI: 10.1016/j.molmet.2018.01.006  1
2018 Rodriguez JA, Zigman JM. Hypothalamic loss of Snord116 and Prader-Willi syndrome hyperphagia: the buck stops here? The Journal of Clinical Investigation. PMID 29376891 DOI: 10.1172/JCI99725  0.68
2017 Mani BK, Zigman JM. Ghrelin as a Survival Hormone. Trends in Endocrinology and Metabolism: Tem. PMID 29097101 DOI: 10.1016/j.tem.2017.10.001  0.52
2017 Mani BK, Osborne-Lawrence S, Mequinion M, Lawrence S, Gautron L, Andrews ZB, Zigman JM. The role of ghrelin-responsive mediobasal hypothalamic neurons in mediating feeding responses to fasting. Molecular Metabolism. 6: 882-896. PMID 28752052 DOI: 10.1016/j.molmet.2017.06.011  0.68
2017 Mani BK, Uchida A, Lee Y, Osborne-Lawrence S, Charron MJ, Unger RH, Berglund ED, Zigman JM. Hypoglycemic Effect of Combined Ghrelin and Glucagon Receptor Blockade. Diabetes. PMID 28487437 DOI: 10.2337/db16-1303  0.68
2017 Cabral A, Cornejo MP, Fernandez G, De Francesco PN, Garcia-Romero G, Uriarte M, Zigman JM, Portiansky E, Reynaldo M, Perello M. Circulating Ghrelin acts on GABA neurons of the area postrema and mediates gastric emptying in male mice. Endocrinology. PMID 28204197 DOI: 10.1210/en.2016-1815  0.68
2017 Chacrabati R, Gong Z, Ikenoya C, Kondo D, Zigman JM, Sakai T, Sakata I. The effect of glutamate on ghrelin release in mice. Cell Biology International. PMID 28067437 DOI: 10.1002/cbin.10728  0.68
2016 Mani BK, Osborne-Lawrence S, Vijayaraghavan P, Hepler C, Zigman JM. β1-Adrenergic receptor deficiency in ghrelin-expressing cells causes hypoglycemia in susceptible individuals. The Journal of Clinical Investigation. PMID 27548523 DOI: 10.1172/JCI86270  0.68
2016 Zigman JM, Bouret SG, Andrews ZB. Correction to 'Obesity Impairs the Action of the Neuroendocrine Ghrelin System': [Trends in Endocrinology and Metabolism, 27 (2016) 54-63]. Trends in Endocrinology and Metabolism: Tem. 27: 348. PMID 27106266 DOI: 10.1016/j.tem.2016.02.007  0.36
2016 Puzziferri N, Zigman JM, Thomas BP, Mihalakos P, Gallagher R, Lutter M, Carmody T, Lu H, Tamminga CA. Brain imaging demonstrates a reduced neural impact of eating in obesity. Obesity (Silver Spring, Md.). PMID 26891710 DOI: 10.1002/oby.21424  1
2016 Cabral A, Portiansky E, Sánchez-Jaramillo E, Zigman JM, Perello M. Ghrelin activates hypophysiotropic corticotropin-releasing factor neurons independently of the arcuate nucleus. Psychoneuroendocrinology. 67: 27-39. PMID 26874559 DOI: 10.1016/j.psyneuen.2016.01.027  0.68
2015 Zigman JM, Bouret SG, Andrews ZB. Obesity Impairs the Action of the Neuroendocrine Ghrelin System. Trends in Endocrinology and Metabolism: Tem. PMID 26542050 DOI: 10.1016/j.tem.2015.09.010  0.36
2015 Mani BK, Zigman JM. A Strong Stomach for Somatostatin. Endocrinology. 156: 3876-9. PMID 26474361 DOI: 10.1210/en.2015-1756  1
2015 Wellman MK, Patterson ZR, MacKay H, Darling JE, Mani BK, Zigman JM, Hougland JL, Abizaid A. Novel Regulator of Acylated Ghrelin, CF801, Reduces Weight Gain, Rebound Feeding after a Fast, and Adiposity in Mice. Frontiers in Endocrinology. 6: 144. PMID 26441834 DOI: 10.3389/fendo.2015.00144  0.52
2015 Engelstoft MS, Lund ML, Grunddal KV, Egerod KL, Osborne-Lawrence S, Poulsen SS, Zigman JM, Schwartz TW. Research Resource: A Chromogranin A Reporter for Serotonin and Histamine Secreting Enteroendocrine Cells. Molecular Endocrinology (Baltimore, Md.). 29: 1658-71. PMID 26352512 DOI: 10.1210/me.2015-1106  1
2015 Müller TD, Nogueiras R, Andermann ML, Andrews ZB, Anker SD, Argente J, Batterham RL, Benoit SC, Bowers CY, Broglio F, Casanueva FF, D'Alessio D, Depoortere I, Geliebter A, Ghigo E, ... ... Zigman JM, et al. Ghrelin. Molecular Metabolism. 4: 437-60. PMID 26042199 DOI: 10.1016/j.molmet.2015.03.005  0.36
2015 De Francesco PN, Valdivia S, Cabral A, Reynaldo M, Raingo J, Sakata I, Osborne-Lawrence S, Zigman JM, Perelló M. Neuroanatomical and functional characterization of CRF neurons of the amygdala using a novel transgenic mouse model. Neuroscience. 289: 153-65. PMID 25595987 DOI: 10.1016/j.neuroscience.2015.01.006  1
2015 Walker AK, Rivera PD, Wang Q, Chuang JC, Tran S, Osborne-Lawrence S, Estill SJ, Starwalt R, Huntington P, Morlock L, Naidoo J, Williams NS, Ready JM, Eisch AJ, Pieper AA, ... Zigman JM, et al. The P7C3 class of neuroprotective compounds exerts antidepressant efficacy in mice by increasing hippocampal neurogenesis. Molecular Psychiatry. 20: 500-8. PMID 24751964 DOI: 10.1038/mp.2014.34  1
2014 Uchida A, Zechner JF, Mani BK, Park WM, Aguirre V, Zigman JM. Altered ghrelin secretion in mice in response to diet-induced obesity and Roux-en-Y gastric bypass. Molecular Metabolism. 3: 717-30. PMID 25353000 DOI: 10.1016/j.molmet.2014.07.009  1
2014 Mani BK, Walker AK, Lopez Soto EJ, Raingo J, Lee CE, Perelló M, Andrews ZB, Zigman JM. Neuroanatomical characterization of a growth hormone secretagogue receptor-green fluorescent protein reporter mouse. The Journal of Comparative Neurology. 522: 3644-66. PMID 24825838 DOI: 10.1002/cne.23627  1
2014 Wang Q, Liu C, Uchida A, Chuang JC, Walker A, Liu T, Osborne-Lawrence S, Mason BL, Mosher C, Berglund ED, Elmquist JK, Zigman JM. Arcuate AgRP neurons mediate orexigenic and glucoregulatory actions of ghrelin. Molecular Metabolism. 3: 64-72. PMID 24567905 DOI: 10.1016/j.molmet.2013.10.001  1
2014 Frazao R, Dungan Lemko HM, da Silva RP, Ratra DV, Lee CE, Williams KW, Zigman JM, Elias CF. Estradiol modulates Kiss1 neuronal response to ghrelin. American Journal of Physiology. Endocrinology and Metabolism. 306: E606-14. PMID 24473434 DOI: 10.1152/ajpendo.00211.2013  1
2014 Gong Z, Yoshimura M, Aizawa S, Kurotani R, Zigman JM, Sakai T, Sakata I. G protein-coupled receptor 120 signaling regulates ghrelin secretion in vivo and in vitro. American Journal of Physiology. Endocrinology and Metabolism. 306: E28-35. PMID 24222669 DOI: 10.1152/ajpendo.00306.2013  0.68
2014 Mani BK, Chuang JC, Kjalarsdottir L, Sakata I, Walker AK, Kuperman A, Osborne-Lawrence S, Repa JJ, Zigman JM. Role of calcium and EPAC in norepinephrine-induced ghrelin secretion. Endocrinology. 155: 98-107. PMID 24189139 DOI: 10.1210/en.2013-1691  1
2014 Mason BL, Wang Q, Zigman JM. The central nervous system sites mediating the orexigenic actions of ghrelin. Annual Review of Physiology. 76: 519-33. PMID 24111557 DOI: 10.1146/annurev-physiol-021113-170310  1
2014 Gong Z, Yoshimura M, Aizawa S, Kurotani R, Zigman JM, Sakai T, Sakata I. G protein-coupled receptor 120 signaling regulates ghrelin secretion in vivo and in vitro American Journal of Physiology - Endocrinology and Metabolism. 306: E28-E35. DOI: 10.1152/ajpendo.00306.2013.  1
2013 Engelstoft MS, Park WM, Sakata I, Kristensen LV, Husted AS, Osborne-Lawrence S, Piper PK, Walker AK, Pedersen MH, Nøhr MK, Pan J, Sinz CJ, Carrington PE, Akiyama TE, Jones RM, ... ... Zigman JM, et al. Seven transmembrane G protein-coupled receptor repertoire of gastric ghrelin cells. Molecular Metabolism. 2: 376-92. PMID 24327954 DOI: 10.1016/j.molmet.2013.08.006  1
2013 Uchida A, Zigman JM, Perelló M. Ghrelin and eating behavior: evidence and insights from genetically-modified mouse models. Frontiers in Neuroscience. 7: 121. PMID 23882175 DOI: 10.3389/fnins.2013.00121  1
2013 Walker AK, Gong Z, Park WM, Zigman JM, Sakata I. Expression of Serum Retinol Binding Protein and Transthyretin within Mouse Gastric Ghrelin Cells. Plos One. 8: e64882. PMID 23840311 DOI: 10.1371/journal.pone.0064882  1
2013 Smith JT, Reichenbach A, Lemus M, Mani BK, Zigman JM, Andrews ZB. An eGFP-expressing subpopulation of growth hormone secretagogue receptor cells are distinct from kisspeptin, tyrosine hydroxylase, and RFamide-related peptide neurons in mice. Peptides. 47: 45-53. PMID 23831041 DOI: 10.1016/j.peptides.2013.06.012  1
2013 Mirfakhraee S, Mathews D, Peng L, Woodruff S, Zigman JM. A solitary hyperfunctioning thyroid nodule harboring thyroid carcinoma: review of the literature. Thyroid Research. 6: 7. PMID 23641736 DOI: 10.1186/1756-6614-6-7  1
2013 Walker AK, Park WM, Chuang JC, Perello M, Sakata I, Osborne-Lawrence S, Zigman JM. Characterization of gastric and neuronal histaminergic populations using a transgenic mouse model. Plos One. 8: e60276. PMID 23555941 DOI: 10.1371/journal.pone.0060276  1
2013 Cravo RM, Frazao R, Perello M, Osborne-Lawrence S, Williams KW, Zigman JM, Vianna C, Elias CF. Leptin signaling in Kiss1 neurons arises after pubertal development. Plos One. 8: e58698. PMID 23505551 DOI: 10.1371/journal.pone.0058698  1
2013 Frazão R, Cravo RM, Donato J, Ratra DV, Clegg DJ, Elmquist JK, Zigman JM, Williams KW, Elias CF. Shift in Kiss1 cell activity requires estrogen receptor α. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 2807-20. PMID 23407940 DOI: 10.1523/JNEUROSCI.1610-12.2013  1
2013 Kumar J, Chuang JC, Na ES, Kuperman A, Gillman AG, Mukherjee S, Zigman JM, McClung CA, Lutter M. Differential effects of chronic social stress and fluoxetine on meal patterns in mice. Appetite. 64: 81-8. PMID 23318656 DOI: 10.1016/j.appet.2012.12.023  1
2013 Elmquist JK, Zigman JM, Saper CB. Mechanisms of homeostatically regulated behaviors Neuroscience in the 21st Century: From Basic to Clinical. 1753-1782. DOI: 10.1007/978-1-4614-1997-6_62  1
2012 Egerod KL, Engelstoft MS, Grunddal KV, Nøhr MK, Secher A, Sakata I, Pedersen J, Windeløv JA, Füchtbauer EM, Olsen J, Sundler F, Christensen JP, Wierup N, Olsen JV, Holst JJ, ... Zigman JM, et al. A major lineage of enteroendocrine cells coexpress CCK, secretin, GIP, GLP-1, PYY, and neurotensin but not somatostatin. Endocrinology. 153: 5782-95. PMID 23064014 DOI: 10.1210/en.2012-1595  1
2012 Walker AK, Ibia IE, Zigman JM. Disruption of cue-potentiated feeding in mice with blocked ghrelin signaling. Physiology & Behavior. 108: 34-43. PMID 23063723 DOI: 10.1016/j.physbeh.2012.10.003  1
2012 Davis JF, Perello M, Choi DL, Magrisso IJ, Kirchner H, Pfluger PT, Tschoep M, Zigman JM, Benoit SC. GOAT induced ghrelin acylation regulates hedonic feeding. Hormones and Behavior. 62: 598-604. PMID 22982020 DOI: 10.1016/j.yhbeh.2012.08.009  1
2012 Scott MM, Perello M, Chuang JC, Sakata I, Gautron L, Lee CE, Lauzon D, Elmquist JK, Zigman JM. Hindbrain ghrelin receptor signaling is sufficient to maintain fasting glucose. Plos One. 7: e44089. PMID 22952883 DOI: 10.1371/journal.pone.0044089  1
2012 Yanovsky Y, Zigman JM, Kernder A, Bein A, Sakata I, Osborne-Lawrence S, Haas HL, Sergeeva OA. Proton- and ammonium-sensing by histaminergic neurons controlling wakefulness. Frontiers in Systems Neuroscience. 6: 23. PMID 22509157 DOI: 10.3389/fnsys.2012.00023  1
2012 Perelló M, Zigman JM. The role of ghrelin in reward-based eating. Biological Psychiatry. 72: 347-53. PMID 22458951 DOI: 10.1016/j.biopsych.2012.02.016  1
2012 Sakata I, Park WM, Walker AK, Piper PK, Chuang JC, Osborne-Lawrence S, Zigman JM. Glucose-mediated control of ghrelin release from primary cultures of gastric mucosal cells. American Journal of Physiology. Endocrinology and Metabolism. 302: E1300-10. PMID 22414807 DOI: 10.1152/ajpendo.00041.2012  1
2012 Cabral A, Suescun O, Zigman JM, Perello M. Ghrelin indirectly activates hypophysiotropic CRF neurons in rodents. Plos One. 7: e31462. PMID 22363652 DOI: 10.1371/journal.pone.0031462  1
2012 Perello M, Scott MM, Sakata I, Lee CE, Chuang JC, Osborne-Lawrence S, Rovinsky SA, Elmquist JK, Zigman JM. Functional implications of limited leptin receptor and ghrelin receptor coexpression in the brain. The Journal of Comparative Neurology. 520: 281-94. PMID 21674492 DOI: 10.1002/cne.22690  1
2012 Yanovsky Y, Zigman JM, Kernder A, Bein A, Sakata I, Osborne-Lawrence S, Haas HL, Sergeeva OA. Proton-and ammonium-sensing by histaminergic neurons controlling wakefulness Frontiers in Systems Neuroscience 1
2011 Chuang JC, Sakata I, Kohno D, Perello M, Osborne-Lawrence S, Repa JJ, Zigman JM. Ghrelin directly stimulates glucagon secretion from pancreatic alpha-cells. Molecular Endocrinology (Baltimore, Md.). 25: 1600-11. PMID 21719535 DOI: 10.1210/me.2011-1001  1
2011 Chuang JC, Perello M, Sakata I, Osborne-Lawrence S, Savitt JM, Lutter M, Zigman JM. Ghrelin mediates stress-induced food-reward behavior in mice. The Journal of Clinical Investigation. 121: 2684-92. PMID 21701068 DOI: 10.1172/JCI57660  1
2011 Klöckener T, Hess S, Belgardt BF, Paeger L, Verhagen LA, Husch A, Sohn JW, Hampel B, Dhillon H, Zigman JM, Lowell BB, Williams KW, Elmquist JK, Horvath TL, Kloppenburg P, et al. High-fat feeding promotes obesity via insulin receptor/PI3K-dependent inhibition of SF-1 VMH neurons. Nature Neuroscience. 14: 911-8. PMID 21642975 DOI: 10.1038/nn.2847  1
2011 Gautron L, Sakata I, Udit S, Zigman JM, Wood JN, Elmquist JK. Genetic tracing of Nav1.8-expressing vagal afferents in the mouse. The Journal of Comparative Neurology. 519: 3085-101. PMID 21618224 DOI: 10.1002/cne.22667  1
2011 Vialou V, Cui H, Perello M, Mahgoub M, Yu HG, Rush AJ, Pranav H, Jung S, Yangisawa M, Zigman JM, Elmquist JK, Nestler EJ, Lutter M. A role for ΔFosB in calorie restriction-induced metabolic changes. Biological Psychiatry. 70: 204-7. PMID 21215388 DOI: 10.1016/j.biopsych.2010.11.027  1
2011 Donato J, Cravo RM, Frazão R, Gautron L, Scott MM, Lachey J, Castro IA, Margatho LO, Lee S, Lee C, Richardson JA, Friedman J, Chua S, Coppari R, Zigman JM, et al. Leptin's effect on puberty in mice is relayed by the ventral premammillary nucleus and does not require signaling in Kiss1 neurons. The Journal of Clinical Investigation. 121: 355-68. PMID 21183787 DOI: 10.1172/JCI45106  1
2011 Cravo RM, Margatho LO, Osborne-Lawrence S, Donato J, Atkin S, Bookout AL, Rovinsky S, Frazão R, Lee CE, Gautron L, Zigman JM, Elias CF. Characterization of Kiss1 neurons using transgenic mouse models. Neuroscience. 173: 37-56. PMID 21093546 DOI: 10.1016/j.neuroscience.2010.11.022  1
2010 Xu Y, Berglund ED, Sohn JW, Holland WL, Chuang JC, Fukuda M, Rossi J, Williams KW, Jones JE, Zigman JM, Lowell BB, Scherer PE, Elmquist JK. 5-HT2CRs expressed by pro-opiomelanocortin neurons regulate insulin sensitivity in liver. Nature Neuroscience. 13: 1457-9. PMID 21037584 DOI: 10.1038/nn.2664  1
2010 Chuang JC, Zigman JM. Ghrelin's Roles in Stress, Mood, and Anxiety Regulation. International Journal of Peptides. 2010. PMID 20721341 DOI: 10.1155/2010/460549  1
2010 Zhao TJ, Sakata I, Li RL, Liang G, Richardson JA, Brown MS, Goldstein JL, Zigman JM. Ghrelin secretion stimulated by {beta}1-adrenergic receptors in cultured ghrelinoma cells and in fasted mice. Proceedings of the National Academy of Sciences of the United States of America. 107: 15868-73. PMID 20713709 DOI: 10.1073/pnas.1011116107  1
2010 Irani BG, Donato J, Olson DP, Lowell BB, Sacktor TC, Reyland ME, Tolson KP, Zinn AR, Ueta Y, Sakata I, Zigman JM, Elias CF, Clegg DJ. Distribution and neurochemical characterization of protein kinase C-theta and -delta in the rodent hypothalamus. Neuroscience. 170: 1065-79. PMID 20691763 DOI: 10.1016/j.neuroscience.2010.07.064  1
2010 Xu Y, Hill JW, Fukuda M, Gautron L, Sohn JW, Kim KW, Lee CE, Choi MJ, Lauzon DA, Dhillon H, Lowell BB, Zigman JM, Zhao JJ, Elmquist JK. PI3K signaling in the ventromedial hypothalamic nucleus is required for normal energy homeostasis. Cell Metabolism. 12: 88-95. PMID 20620998 DOI: 10.1016/j.cmet.2010.05.002  1
2010 Hill JW, Elias CF, Fukuda M, Williams KW, Berglund ED, Holland WL, Cho YR, Chuang JC, Xu Y, Choi M, Lauzon D, Lee CE, Coppari R, Richardson JA, Zigman JM, et al. Direct insulin and leptin action on pro-opiomelanocortin neurons is required for normal glucose homeostasis and fertility. Cell Metabolism. 11: 286-97. PMID 20374961 DOI: 10.1016/j.cmet.2010.03.002  1
2010 Chuang JC, Cui H, Mason BL, Mahgoub M, Bookout AL, Yu HG, Perello M, Elmquist JK, Repa JJ, Zigman JM, Lutter M. Chronic social defeat stress disrupts regulation of lipid synthesis. Journal of Lipid Research. 51: 1344-53. PMID 20129912 DOI: 10.1194/jlr.M002196  1
2010 Chuang JC, Krishnan V, Yu HG, Mason B, Cui H, Cui H, Wilkinson MB, Zigman JM, Elmquist JK, Nestler EJ, Lutter M. A beta3-adrenergic-leptin-melanocortin circuit regulates behavioral and metabolic changes induced by chronic stress. Biological Psychiatry. 67: 1075-82. PMID 20060958 DOI: 10.1016/j.biopsych.2009.12.003  1
2010 Perello M, Sakata I, Birnbaum S, Chuang JC, Osborne-Lawrence S, Rovinsky SA, Woloszyn J, Yanagisawa M, Lutter M, Zigman JM. Ghrelin increases the rewarding value of high-fat diet in an orexin-dependent manner. Biological Psychiatry. 67: 880-6. PMID 20034618 DOI: 10.1016/j.biopsych.2009.10.030  1
2009 Andrews ZB, Erion D, Beiler R, Liu ZW, Abizaid A, Zigman J, Elsworth JD, Savitt JM, DiMarchi R, Tschoep M, Roth RH, Gao XB, Horvath TL. Ghrelin promotes and protects nigrostriatal dopamine function via a UCP2-dependent mitochondrial mechanism. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 14057-65. PMID 19906954 DOI: 10.1523/JNEUROSCI.3890-09.2009  1
2009 Sakata I, Yang J, Lee CE, Osborne-Lawrence S, Rovinsky SA, Elmquist JK, Zigman JM. Colocalization of ghrelin O-acyltransferase and ghrelin in gastric mucosal cells. American Journal of Physiology. Endocrinology and Metabolism. 297: E134-41. PMID 19401456 DOI: 10.1152/ajpendo.90859.2008  1
2009 Sakata I, Nakano Y, Osborne-Lawrence S, Rovinsky SA, Lee CE, Perello M, Anderson JG, Coppari R, Xiao G, Lowell BB, Elmquist JK, Zigman JM. Characterization of a novel ghrelin cell reporter mouse. Regulatory Peptides. 155: 91-8. PMID 19361544 DOI: 10.1016/j.regpep.2009.04.001  1
2009 Davies JS, Kotokorpi P, Eccles SR, Barnes SK, Tokarczuk PF, Allen SK, Whitworth HS, Guschina IA, Evans BA, Mode A, Zigman JM, Wells T. Ghrelin induces abdominal obesity via GHS-R-dependent lipid retention. Molecular Endocrinology (Baltimore, Md.). 23: 914-24. PMID 19299444 DOI: 10.1210/me.2008-0432  1
2008 Fukuda M, Jones JE, Olson D, Hill J, Lee CE, Gautron L, Choi M, Zigman JM, Lowell BB, Elmquist JK. Monitoring FoxO1 localization in chemically identified neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 13640-8. PMID 19074037 DOI: 10.1523/JNEUROSCI.4023-08.2008  1
2008 Xu Y, Jones JE, Kohno D, Williams KW, Lee CE, Choi MJ, Anderson JG, Heisler LK, Zigman JM, Lowell BB, Elmquist JK. 5-HT2CRs expressed by pro-opiomelanocortin neurons regulate energy homeostasis. Neuron. 60: 582-9. PMID 19038216 DOI: 10.1016/j.neuron.2008.09.033  1
2008 Lutter M, Sakata I, Osborne-Lawrence S, Rovinsky SA, Anderson JG, Jung S, Birnbaum S, Yanagisawa M, Elmquist JK, Nestler EJ, Zigman JM. The orexigenic hormone ghrelin defends against depressive symptoms of chronic stress. Nature Neuroscience. 11: 752-3. PMID 18552842 DOI: 10.1038/nn.2139  1
2008 Nogueiras R, Tschöp MH, Zigman JM. Central nervous system regulation of energy metabolism: ghrelin versus leptin. Annals of the New York Academy of Sciences. 1126: 14-9. PMID 18448790 DOI: 10.1196/annals.1433.054  1
2007 Tong Q, Ye C, McCrimmon RJ, Dhillon H, Choi B, Kramer MD, Yu J, Yang Z, Christiansen LM, Lee CE, Choi CS, Zigman JM, Shulman GI, Sherwin RS, Elmquist JK, et al. Synaptic glutamate release by ventromedial hypothalamic neurons is part of the neurocircuitry that prevents hypoglycemia. Cell Metabolism. 5: 383-93. PMID 17488640 DOI: 10.1016/j.cmet.2007.04.001  1
2007 Clegg DJ, Brown LM, Zigman JM, Kemp CJ, Strader AD, Benoit SC, Woods SC, Mangiaracina M, Geary N. Estradiol-dependent decrease in the orexigenic potency of ghrelin in female rats. Diabetes. 56: 1051-8. PMID 17251274 DOI: 10.2337/db06-0015  1
2006 Zigman JM, Elmquist JK. In search of an effective obesity treatment: a shot in the dark or a shot in the arm? Proceedings of the National Academy of Sciences of the United States of America. 103: 12961-2. PMID 16924097 DOI: 10.1073/pnas.0605959103  1
2006 Heisler LK, Jobst EE, Sutton GM, Zhou L, Borok E, Thornton-Jones Z, Liu HY, Zigman JM, Balthasar N, Kishi T, Lee CE, Aschkenasi CJ, Zhang CY, Yu J, Boss O, et al. Serotonin reciprocally regulates melanocortin neurons to modulate food intake. Neuron. 51: 239-49. PMID 16846858 DOI: 10.1016/j.neuron.2006.06.004  1
2006 Elmquist J, Zigman J, Lutter M. Molecular determinants of energy homeostasis. The American Journal of Psychiatry. 163: 1137. PMID 16816215 DOI: 10.1176/appi.ajp.163.7.1137  1
2006 Dhillon H, Zigman JM, Ye C, Lee CE, McGovern RA, Tang V, Kenny CD, Christiansen LM, White RD, Edelstein EA, Coppari R, Balthasar N, Cowley MA, Chua S, Elmquist JK, et al. Leptin directly activates SF1 neurons in the VMH, and this action by leptin is required for normal body-weight homeostasis. Neuron. 49: 191-203. PMID 16423694 DOI: 10.1016/j.neuron.2005.12.021  1
2006 Zigman JM, Jones JE, Lee CE, Saper CB, Elmquist JK. Expression of ghrelin receptor mRNA in the rat and the mouse brain. The Journal of Comparative Neurology. 494: 528-48. PMID 16320257 DOI: 10.1002/cne.20823  1
2005 Zigman JM, Nakano Y, Coppari R, Balthasar N, Marcus JN, Lee CE, Jones JE, Deysher AE, Waxman AR, White RD, Williams TD, Lachey JL, Seeley RJ, Lowell BB, Elmquist JK. Mice lacking ghrelin receptors resist the development of diet-induced obesity. The Journal of Clinical Investigation. 115: 3564-72. PMID 16322794 DOI: 10.1172/JCI26002  1
2004 Glinoer D, Zigman JM, Garber JR. Increased TBG during pregnancy and increased hormonal requirements (multiple letters) Thyroid. 14: 479-481. PMID 15242581 DOI: 10.1089/105072504323150859  1
2003 Zigman JM, Cohen SE, Garber JR. Impact of thyroxine-binding globulin on thyroid hormone economy during pregnancy. Thyroid : Official Journal of the American Thyroid Association. 13: 1169-75. PMID 14751039 DOI: 10.1089/10507250360731587  1
2003 Zigman JM, Elmquist JK. Minireview: From anorexia to obesity--the yin and yang of body weight control. Endocrinology. 144: 3749-56. PMID 12933644 DOI: 10.1210/en.2003-0241  1
2003 Heisler LK, Cowley MA, Kishi T, Tecott LH, Fan W, Low MJ, Smart JL, Rubinstein M, Tatro J, Zigman JM, Cone RD, Elmquist JK. Central serotonin and melanocortin pathways regulating energy homeostasis. Annals of the New York Academy of Sciences. 994: 169-74. PMID 12851313  1
1994 Zigman JM, Westermark GT, LaMendola J, Steiner DF. Expression of cone transducin, Gz alpha, and other G-protein alpha-subunit messenger ribonucleic acids in pancreatic islets. Endocrinology. 135: 31-7. PMID 8013366 DOI: 10.1210/endo.135.1.8013366  1
1993 Zigman JM, Westermark GT, LaMendola J, Boel E, Steiner DF. Human G(olf) alpha: complementary deoxyribonucleic acid structure and expression in pancreatic islets and other tissues outside the olfactory neuroepithelium and central nervous system. Endocrinology. 133: 2508-14. PMID 8243272 DOI: 10.1210/endo.133.6.8243272  1
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