Jeffrey M. Zigman, M.D., Ph.D. - Related publications

University of Texas Southwestern Medical Center, Dallas, TX, United States 
Gut-brain control of eating behavior
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50 most relevant papers in past 60 days:
Year Citation  Score
2020 Singha A, Palavicini JP, Pan M, Farmer S, Sandoval D, Han X, Fujikawa T. Leptin Receptors in RIP-Cre Neurons Mediate Anti-dyslipidemia Effects of Leptin in Insulin-Deficient Mice. Frontiers in Endocrinology. 11: 588447. PMID 33071988 DOI: 10.3389/fendo.2020.588447   
2020 Al Helaili A, Park SJ, Beyak MJ. Chronic high fat diet impairs glucagon like peptide-1 sensitivity in vagal afferents. Biochemical and Biophysical Research Communications. PMID 32943186 DOI: 10.1016/j.bbrc.2020.08.045   
2020 Dakic T, Jevdjovic T, Djordjevic J, Vujovic P. Short-term fasting differentially regulates PI3K/AkT/mTOR and ERK signalling in the rat hypothalamus. Mechanisms of Ageing and Development. 111358. PMID 32961167 DOI: 10.1016/j.mad.2020.111358   
2020 Lu SC, Akanji AO. Leptin, Obesity, and Hypertension: A Review of Pathogenetic Mechanisms. Metabolic Syndrome and Related Disorders. PMID 32876506 DOI: 10.1089/met.2020.0065   
2020 Han X, Burger LL, Garcia-Galiano D, Sim S, Allen SJ, Olson DP, Myers MG, Elias CF. Hypothalamic and Cell-Specific Transcriptomes Unravel a Dynamic Neuropil Remodeling in Leptin-Induced and Typical Pubertal Transition in Female Mice. Iscience. 23: 101563. PMID 33083731 DOI: 10.1016/j.isci.2020.101563   
2020 Zhu M, Wang Q, Tian P, Cheng L, Sun Z, Hong Q, Lv P, Ji L, Liu Y, Tang QQ, Wen B. A long non-coding RNA specifically expressed in early embryos programs the metabolic balance in adult mice. Biochimica Et Biophysica Acta. Molecular Basis of Disease. 165988. PMID 33059001 DOI: 10.1016/j.bbadis.2020.165988   
2020 Grunewald ZI, Ramirez-Perez FI, Woodford ML, Morales-Quinones M, Mejia S, Manrique-Acevedo C, Siebenlist U, Martinez-Lemus LA, Chandrasekar B, Padilla J. TRAF3IP2 (TRAF3 Interacting Protein 2) Mediates Obesity-Associated Vascular Insulin Resistance and Dysfunction in Male Mice. Hypertension (Dallas, Tex. : 1979). 76: 1319-1329. PMID 32829657 DOI: 10.1161/HYPERTENSIONAHA.120.15262   
2020 Xu MX, Dai XL, Kuang Q, Zhu LC, Hu LF, Lou DS, Li Q, Feng J, Wu YK, Ge CX, Wang BC, Tan J. Dysfunctional Rhbdf2 of proopiomelanocortin mitigates ambient particulate matter exposure-induced neurological injury and neuron loss by antagonizing oxidative stress and inflammatory reaction. Journal of Hazardous Materials. 400: 123158. PMID 32947736 DOI: 10.1016/j.jhazmat.2020.123158   
2020 Rodriguez S, Little HC, Daneshpajouhnejad P, Fenaroli P, Tan SY, Sarver DC, Delannoy M, Talbot CC, Jandu S, Berkowitz DE, Pluznick JL, Rosenberg AZ, Wong GW. Aging and chronic high-fat feeding negatively affects kidney size, function, and gene expression in CTRP1-deficient mice. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. PMID 33085906 DOI: 10.1152/ajpregu.00139.2020   
2020 Ming X, Chung ACK, Mao D, Cao H, Fan B, Wong WKK, Ho CC, Lee HM, Schoonjans K, Auwerx J, Rutter GA, Chan JCN, Tian XY, Kong APS. Pancreatic Sirtuin 3 Deficiency Promotes Hepatic Steatosis by Enhancing 5-Hydroxytryptamine Synthesis in Diet-Induced Obese Mice. Diabetes. PMID 33087457 DOI: 10.2337/db20-0339   
2020 Fonseca CSM, Basford JE, Kuhel DG, Konaniah ES, Cash JG, Lima VLM, Hui DY. Distinct Influence of Hypercaloric Diets Predominant with Fat or Fat and Sucrose on Adipose Tissue and Liver Inflammation in Mice. Molecules (Basel, Switzerland). 25. PMID 32977558 DOI: 10.3390/molecules25194369   
2020 Xu Y, Wang N, Tan HY, Li S, Zhang C, Zhang Z, Feng Y. saponins modulate the gut microbiota to promote thermogenesis and beige adipocyte reconstruction leptin-mediated AMPKα/STAT3 signaling in diet-induced obesity. Theranostics. 10: 11302-11323. PMID 33042284 DOI: 10.7150/thno.47746   
2020 Zheng X, Ren B, Li X, Yan H, Xie Q, Liu H, Zhou J, Tian J, Huang K. Selenoprotein F knockout leads to glucose and lipid metabolism disorders in mice. Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry. PMID 32995962 DOI: 10.1007/s00775-020-01821-z   
2020 Kubota S, Liu Y, Iizuka K, Kuwata H, Seino Y, Yabe D. A Review of Recent Findings on Meal Sequence: An Attractive Dietary Approach to Prevention and Management of Type 2 Diabetes. Nutrients. 12. PMID 32825124 DOI: 10.3390/nu12092502   
2020 Koboziev I, Scoggin S, Gong X, Mirzaei P, Zabet-Moghaddam M, Yosofvand M, Moussa H, Jones-Hall Y, Moustaid-Moussa N. Effects of Curcumin in a Mouse Model of Very High Fat Diet-Induced Obesity. Biomolecules. 10. PMID 32992936 DOI: 10.3390/biom10101368   
2020 Huang KP, Goodson ML, Vang W, Li H, Page AJ, Raybould HE. Leptin signaling in vagal afferent neurons supports the absorption and storage of nutrients from high-fat diet. International Journal of Obesity (2005). PMID 32917985 DOI: 10.1038/s41366-020-00678-1   
2020 Yeh CL, Yang PJ, Lee PC, Wu JM, Chen PD, Huang CC, Yeh SL, Lin MT. Intravenous Glutamine Administration Improves Glucose Tolerance and Attenuates the Inflammatory Response in Diet-Induced Obese Mice after Sleeve Gastrectomy. Nutrients. 12. PMID 33086562 DOI: 10.3390/nu12103192   
2020 Yang M, Bose S, Lim S, Seo J, Shin J, Lee D, Chung WH, Song EJ, Nam YD, Kim H. Beneficial Effects of Newly Isolated Strains from the Human Gut on Obesity and Metabolic Dysregulation. Microorganisms. 8. PMID 32937828 DOI: 10.3390/microorganisms8091413   
2020 Komalla V, Sheikholeslami B, Li G, Bokshi B, Chan YL, Ung A, Gregory Oliver B, Chen H, Haghi M. Impact of A Cargo-Less Liposomal Formulation on Dietary Obesity-Related Metabolic Disorders in Mice. International Journal of Molecular Sciences. 21. PMID 33076522 DOI: 10.3390/ijms21207640   
2020 Wang B, Kong Q, Li X, Zhao J, Zhang H, Chen W, Wang G. A High-Fat Diet Increases Gut Microbiota Biodiversity and Energy Expenditure Due to Nutrient Difference. Nutrients. 12. PMID 33092019 DOI: 10.3390/nu12103197   
2020 Shin SK, Cho HW, Song SE, Im SS, Bae JH, Song DK. Oxidative stress resulting from the removal of endogenous catalase induces obesity by promoting hyperplasia and hypertrophy of white adipocytes. Redox Biology. 37: 101749. PMID 33080438 DOI: 10.1016/j.redox.2020.101749   
2020 Tian T, Heine M, Evangelakos I, Jaeckstein MY, Schaltenberg N, Stähler T, Koch-Nolte F, Kumari M, Heeren J. The P2X7 ion channel is dispensable for energy and metabolic homeostasis of white and brown adipose tissues. Purinergic Signalling. PMID 33025427 DOI: 10.1007/s11302-020-09738-7   
2020 Reginato A, Siqueira BP, Miyamoto JÉ, Portovedo M, Costa SO, de Fante T, Rodrigues HG, Ignácio-Souza LM, Torsoni MA, Torsoni AS, Le Stunff H, Belsham DD, Milanski M. Acute effects of fatty acids on autophagy in NPY neurones. Journal of Neuroendocrinology. 32: e12900. PMID 33040385 DOI: 10.1111/jne.12900   
2020 Ae Kang S, Ho Choi J, Baek KW, In Lee D, Jeong MJ, Sun Yu H. Trichinella spiralis infection ameliorated diet-induced obesity model in mice. International Journal For Parasitology. PMID 32966835 DOI: 10.1016/j.ijpara.2020.07.012   
2020 Gilani A, Agostinucci K, Hossain S, Pascale JV, Garcia V, Adebesin AM, Falck JR, Schwartzman ML. 20-HETE Interferes with Insulin Signaling and Contributes to Obesity-Driven Insulin Resistance. Prostaglandins & Other Lipid Mediators. 106485. PMID 33011364 DOI: 10.1016/j.prostaglandins.2020.106485   
2020 Yang G, Hong E, Oh S, Kim E. Non-Viable JNU3402 Protects against Diet-Induced Obesity. Foods (Basel, Switzerland). 9. PMID 33086627 DOI: 10.3390/foods9101494   
2020 Zhong X, Ke C, Cai Z, Wu H, Ye Y, Liang X, Yu L, Jiang S, Shen J, Wang L, Xie M, Wang G, Zhao X. LNK deficiency decreases obesity-induced insulin resistance by regulating GLUT4 through the PI3K-Akt-AS160 pathway in adipose tissue. Aging. 12. PMID 32911464 DOI: 10.18632/aging.103658   
2020 Chen T, Chen C, Wu H, Chen X, Xie R, Wang F, Sun H, Chen L. Overexpression of accelerates puberty in high-fat diet-fed mice through system. Experimental Biology and Medicine (Maywood, N.J.). 1535370220961320. PMID 32996351 DOI: 10.1177/1535370220961320   
2020 Cox AR, Chernis N, Bader DA, Saha PK, Masschelin PM, Felix JB, Sharp R, Lian Z, Putluri V, Rajapakshe K, Kim KH, Villareal DT, Armamento-Villareal R, Wu H, Coarfa C, et al. STAT1 Dissociates Adipose Tissue Inflammation From Insulin Sensitivity in Obesity. Diabetes. PMID 32994273 DOI: 10.2337/db20-0384   
2020 Wang DC, Yan TT, Chen B, Liu F, Liu XP, Xie YM. SIS3, a good candidate for the reverse of type 2 diabetes mellitus in mice. Fundamental & Clinical Pharmacology. PMID 33022778 DOI: 10.1111/fcp.12611   
2020 Yang HR, Tu TH, Jeong DY, Yang S, Kim JG. Obesity induced by estrogen deficiency is associated with hypothalamic inflammation. Biochemistry and Biophysics Reports. 23: 100794. PMID 32885054 DOI: 10.1016/j.bbrep.2020.100794   
2020 Sakai Y, Arie H, Ni Y, Zhuge F, Xu L, Chen G, Nagata N, Suzuki T, Kaneko S, Ota T, Nagashimada M. Lactobacillus pentosus strain S-PT84 improves steatohepatitis by maintaining gut permeability. The Journal of Endocrinology. 247: 169-181. PMID 33032263 DOI: 10.1530/JOE-20-0105   
2020 Li L, Li R, Zhu R, Chen B, Tian Y, Zhang H, Xia B, Jia Q, Wang L, Zhao D, Mo F, Li Y, Zhang S, Gao S, Zhang D, et al. Salvianolic acid B prevents body weight gain and regulates gut microbiota and LPS/TLR4 signaling pathway in high-fat diet-induced obese mice. Food & Function. PMID 32955050 DOI: 10.1039/d0fo01116a   
2020 Song K, Zhang Y, Ga Q, Bai Z, Ge RL. Increased Insulin Sensitivity by High-Altitude Hypoxia in Mice with High-Fat Diet-Induced Obesity Is Associated with Activated AMPK Signaling and Subsequently Enhanced Mitochondrial Biogenesis in Skeletal Muscles. Obesity Facts. 1-18. PMID 32966981 DOI: 10.1159/000508112   
2020 Plucińska K, Jespersen NZ, Brown EL, Petersen PS, Rupar K, Nielsen S, Scheele C, Emanuelli B. Calsyntenin 3β Is Dynamically Regulated by Temperature in Murine Brown Adipose and Marks Human Multilocular Fat. Frontiers in Endocrinology. 11: 579785. PMID 33101212 DOI: 10.3389/fendo.2020.579785   
2020 Reilly AM, Tsai AP, Lin PB, Ericsson AC, Oblak AL, Ren H. Metabolic Defects Caused by High-Fat Diet Modify Disease Risk through Inflammatory and Amyloidogenic Pathways in a Mouse Model of Alzheimer's Disease. Nutrients. 12. PMID 33003412 DOI: 10.3390/nu12102977   
2020 Turk J, Song H, Wohltmann M, Frankfater C, Lei X, Ramanadham S. Metabolic Effects of Selective Deletion of Group VIA Phospholipase A from Macrophages or Pancreatic Islet Beta-Cells. Biomolecules. 10. PMID 33080873 DOI: 10.3390/biom10101455   
2020 Santos JL, Cortés VA. Eating behaviour in contrasting adiposity phenotypes: Monogenic obesity and congenital generalized lipodystrophy. Obesity Reviews : An Official Journal of the International Association For the Study of Obesity. PMID 33030294 DOI: 10.1111/obr.13114   
2020 Angelini G, Castagneto Gissey L, Casella Mariolo J, Caristo ME, Russo MF, Lembo E, Verrastro O, Stefanizzi G, Marini PL, Casella G, Bornstein SR, Rubino F, Mingrone G. Duodenal-Jejunal Bypass Improves Non-alcoholic Fatty Liver Disease Independently of Weight Loss in Rodents with Diet-Induced Obesity. American Journal of Physiology. Gastrointestinal and Liver Physiology. PMID 32812775 DOI: 10.1152/ajpgi.00357.2019   
2020 Fujima S, Amemiya N, Arima T, Sano Y, Furuichi T. CAPS2 deficiency induces proopiomelanocortin accumulation in pituitary and affects food intake behavior in mice. Neuroscience Letters. 135335. PMID 32891671 DOI: 10.1016/j.neulet.2020.135335   
2020 Baron M, Froguel P, Bonnefond A. [Something new in the genetics of monogenic obesity and its insights into pathophysiology]. Medecine Sciences : M/S. 36: 859-865. PMID 33026327 DOI: 10.1051/medsci/2020156   
2020 Zhang Q, Kim JH, Kim Y, Kim W. Lactococcus chungangensis CAU 28 alleviates diet-induced obesity and adipose tissue metabolism in vitro and in mice fed a high-fat diet. Journal of Dairy Science. PMID 32896398 DOI: 10.3168/jds.2020-18681   
2020 Régnier M, Rastelli M, Morissette A, Suriano F, Le Roy T, Pilon G, Delzenne NM, Marette A, Van Hul M, Cani PD. Rhubarb Supplementation Prevents Diet-Induced Obesity and Diabetes in Association with Increased in Mice. Nutrients. 12. PMID 32987923 DOI: 10.3390/nu12102932   
2020 Ma C, Guo Y, Klaassen CD. . Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 33093018 DOI: 10.1124/dmd.120.000166   
2020 Zhao L, Fan M, Zhao L, Yun H, Yang Y, Wang C, Qin D. Fibroblast growth factor 1 ameliorates adipose tissue inflammation and systemic insulin resistance via enhancing adipocyte mTORC2/Rictor signal. Journal of Cellular and Molecular Medicine. PMID 32979037 DOI: 10.1111/jcmm.15872   
2020 Wang G, Yu Y, Cai W, Batista TM, Suk S, Noh HL, Hirshman M, Nigro P, Li ME, Softic S, Goodyear L, Kim JK, Kahn CR. Muscle Specific Insulin Receptor Overexpression Protects Mice from Diet-Induced Glucose Intolerance but Leads to Post-Receptor Insulin Resistance. Diabetes. PMID 32868340 DOI: 10.2337/db20-0439   
2020 Berger E, Colosetti P, Jalabert A, Meugnier E, Wiklander OPB, Jouhet J, Errazurig-Cerda E, Chanon S, Gupta D, Rautureau GJP, Geloen A, El-Andaloussi S, Panthu B, Rieusset J, Rome S. Use of Nanovesicles from Orange Juice to Reverse Diet-Induced Gut Modifications in Diet-Induced Obese Mice. Molecular Therapy. Methods & Clinical Development. 18: 880-892. PMID 32953937 DOI: 10.1016/j.omtm.2020.08.009   
2020 Berger E, Colosetti P, Jalabert A, Meugnier E, Wiklander OPB, Jouhet J, Errazurig-Cerda E, Chanon S, Gupta D, Rautureau GJP, Geloen A, El-Andaloussi S, Panthu B, Rieusset J, Rome S. Use of Nanovesicles from Orange Juice to Reverse Diet-Induced Gut Modifications in Diet-Induced Obese Mice. Molecular Therapy. Methods & Clinical Development. 18: 880-892. PMID 32953937 DOI: 10.1016/j.omtm.2020.08.009   
2020 van den Hoek AM, Verschuren L, Worms N, van Nieuwkoop A, de Ruiter C, Attema J, Menke AL, Caspers MPM, Radhakrishnan S, Salic K, Kleemann R. A Translational Mouse Model for NASH with Advanced Fibrosis and Atherosclerosis Expressing Key Pathways of Human Pathology. Cells. 9. PMID 32883049 DOI: 10.3390/cells9092014   
2020 Bonds JA, Shetti A, Stephen TKL, Bonini MG, Minshall RD, Lazarov O. Deficits in hippocampal neurogenesis in obesity-dependent and -independent type-2 diabetes mellitus mouse models. Scientific Reports. 10: 16368. PMID 33004912 DOI: 10.1038/s41598-020-73401-9