| Year |
Citation |
Score |
| 2023 |
Groh J, Abdelwahab T, Kattimani Y, Hörner M, Loserth S, Gudi V, Adalbert R, Imdahl F, Saliba AE, Coleman M, Stangel M, Simons M, Martini R. Microglia-mediated demyelination protects against CD8 T cell-driven axon degeneration in mice carrying PLP defects. Nature Communications. 14: 6911. PMID 37903797 DOI: 10.1038/s41467-023-42570-2 |
0.459 |
|
| 2023 |
Depp C, Sun T, Sasmita AO, Spieth L, Berghoff SA, Nazarenko T, Overhoff K, Steixner-Kumar AA, Subramanian S, Arinrad S, Ruhwedel T, Möbius W, Göbbels S, Saher G, Werner HB, ... ... Simons M, et al. Myelin dysfunction drives amyloid-β deposition in models of Alzheimer's disease. Nature. PMID 37258678 DOI: 10.1038/s41586-023-06120-6 |
0.386 |
|
| 2023 |
Djannatian M, Radha S, Weikert U, Safaiyan S, Wrede C, Deichsel C, Kislinger G, Rhomberg A, Ruhwedel T, Campbell DS, van Ham T, Schmid B, Hegermann J, Möbius W, Schifferer M, ... Simons M, et al. Myelination generates aberrant ultrastructure that is resolved by microglia. The Journal of Cell Biology. 222. PMID 36637807 DOI: 10.1083/jcb.202204010 |
0.479 |
|
| 2022 |
Paolicelli RC, Sierra A, Stevens B, Tremblay ME, Aguzzi A, Ajami B, Amit I, Audinat E, Bechmann I, Bennett M, Bennett F, Bessis A, Biber K, Bilbo S, Blurton-Jones M, ... ... Simons M, et al. Microglia states and nomenclature: A field at its crossroads. Neuron. 110: 3458-3483. PMID 36327895 DOI: 10.1016/j.neuron.2022.10.020 |
0.475 |
|
| 2022 |
Arends M, Weber M, Papan C, Damm M, Surma MA, Spiegel C, Djannatian M, Li S, Connell L, Johannes L, Schifferer M, Klose C, Simons M. Ganglioside lipidomics of CNS myelination using direct infusion shotgun mass spectrometry. Iscience. 25: 105323. PMID 36310581 DOI: 10.1016/j.isci.2022.105323 |
0.435 |
|
| 2022 |
Franklin RJM, Simons M. CNS remyelination and inflammation: From basic mechanisms to therapeutic opportunities. Neuron. 110: 3549-3565. PMID 36228613 DOI: 10.1016/j.neuron.2022.09.023 |
0.38 |
|
| 2021 |
Gouna G, Klose C, Bosch-Queralt M, Liu L, Gokce O, Schifferer M, Cantuti-Castelvetri L, Simons M. TREM2-dependent lipid droplet biogenesis in phagocytes is required for remyelination. The Journal of Experimental Medicine. 218. PMID 34424266 DOI: 10.1084/jem.20210227 |
0.363 |
|
| 2021 |
Bosch-Queralt M, Cantuti-Castelvetri L, Damkou A, Schifferer M, Schlepckow K, Alexopoulos I, Lütjohann D, Klose C, Vaculčiaková L, Masuda T, Prinz M, Monroe KM, Di Paolo G, Lewcock JW, Haass C, ... Simons M, et al. Diet-dependent regulation of TGFβ impairs reparative innate immune responses after demyelination. Nature Metabolism. 3: 211-227. PMID 33619376 DOI: 10.1038/s42255-021-00341-7 |
0.329 |
|
| 2021 |
Safaiyan S, Besson-Girard S, Kaya T, Cantuti-Castelvetri L, Liu L, Ji H, Schifferer M, Gouna G, Usifo F, Kannaiyan N, Fitzner D, Xiang X, Rossner MJ, Brendel M, Gokce O, ... Simons M, et al. White matter aging drives microglial diversity. Neuron. PMID 33606969 DOI: 10.1016/j.neuron.2021.01.027 |
0.342 |
|
| 2020 |
Berghoff SA, Spieth L, Sun T, Hosang L, Schlaphoff L, Depp C, Düking T, Winchenbach J, Neuber J, Ewers D, Scholz P, van der Meer F, Cantuti-Castelvetri L, Sasmita AO, Meschkat M, ... ... Simons M, et al. Microglia facilitate repair of demyelinated lesions via post-squalene sterol synthesis. Nature Neuroscience. PMID 33349711 DOI: 10.1038/s41593-020-00757-6 |
0.346 |
|
| 2020 |
Tüshaus J, Müller SA, Kataka ES, Zaucha J, Sebastian Monasor L, Su M, Güner G, Jocher G, Tahirovic S, Frishman D, Simons M, Lichtenthaler SF. An optimized quantitative proteomics method establishes the cell type-resolved mouse brain secretome. The Embo Journal. e105693. PMID 32954517 DOI: 10.15252/Embj.2020105693 |
0.753 |
|
| 2020 |
Fitzner D, Bader JM, Penkert H, Bergner CG, Su M, Weil MT, Surma MA, Mann M, Klose C, Simons M. Cell-Type- and Brain-Region-Resolved Mouse Brain Lipidome. Cell Reports. 32: 108132. PMID 32937123 DOI: 10.1016/J.Celrep.2020.108132 |
0.745 |
|
| 2020 |
Mukherjee C, Kling T, Russo B, Miebach K, Kess E, Schifferer M, Pedro LD, Weikert U, Fard MK, Kannaiyan N, Rossner M, Aicher ML, Goebbels S, Nave KA, Krämer-Albers EM, ... ... Simons M, et al. Oligodendrocytes Provide Antioxidant Defense Function for Neurons by Secreting Ferritin Heavy Chain. Cell Metabolism. PMID 32531201 DOI: 10.1016/J.Cmet.2020.05.019 |
0.428 |
|
| 2020 |
Cunha MI, Su M, Cantuti-Castelvetri L, Müller SA, Schifferer M, Djannatian M, Alexopoulos I, van der Meer F, Winkler A, van Ham TJ, Schmid B, Lichtenthaler SF, Stadelmann C, Simons M. Pro-inflammatory activation following demyelination is required for myelin clearance and oligodendrogenesis. The Journal of Experimental Medicine. 217. PMID 32078678 DOI: 10.1084/Jem.20191390 |
0.78 |
|
| 2020 |
Miller RH, Simons M, Emery B. Decision letter: Remyelination alters the pattern of myelin in the cerebral cortex Elife. DOI: 10.7554/Elife.56621.Sa1 |
0.402 |
|
| 2019 |
Djannatian M, Timmler S, Arends M, Luckner M, Weil MT, Alexopoulos I, Snaidero N, Schmid B, Misgeld T, Möbius W, Schifferer M, Peles E, Simons M. Two adhesive systems cooperatively regulate axon ensheathment and myelin growth in the CNS. Nature Communications. 10: 4794. PMID 31641127 DOI: 10.1038/S41467-019-12789-Z |
0.772 |
|
| 2019 |
Stadelmann C, Timmler S, Barrantes-Freer A, Simons M. Myelin in the Central Nervous System: Structure, Function, and Pathology. Physiological Reviews. 99: 1381-1431. PMID 31066630 DOI: 10.1152/Physrev.00031.2018 |
0.781 |
|
| 2019 |
Timmler S, Simons M. Grey matter myelination. Glia. PMID 30860619 DOI: 10.1002/Glia.23614 |
0.77 |
|
| 2019 |
Weil MT, Schulz-Ëberlin G, Mukherjee C, Kuo-Elsner WP, Schäfer I, Müller C, Simons M. Isolation and Culture of Oligodendrocytes. Methods in Molecular Biology (Clifton, N.J.). 1936: 79-95. PMID 30820894 DOI: 10.1007/978-1-4939-9072-6_5 |
0.399 |
|
| 2018 |
Cantuti-Castelvetri L, Fitzner D, Bosch-Queralt M, Weil MT, Su M, Sen P, Ruhwedel T, Mitkovski M, Trendelenburg G, Lütjohann D, Möbius W, Simons M. Defective cholesterol clearance limits remyelination in the aged central nervous system. Science (New York, N.Y.). PMID 29301957 DOI: 10.1126/Science.Aan4183 |
0.78 |
|
| 2017 |
Fard MK, van der Meer F, Sánchez P, Cantuti-Castelvetri L, Mandad S, Jäkel S, Fornasiero EF, Schmitt S, Ehrlich M, Starost L, Kuhlmann T, Sergiou C, Schultz V, Wrzos C, Brück W, ... ... Simons M, et al. BCAS1 expression defines a population of early myelinating oligodendrocytes in multiple sclerosis lesions. Science Translational Medicine. 9. PMID 29212715 DOI: 10.1126/Scitranslmed.Aam7816 |
0.53 |
|
| 2017 |
Dimou L, Simons M. Diversity of oligodendrocytes and their progenitors. Current Opinion in Neurobiology. 47: 73-79. PMID 29078110 DOI: 10.1016/J.Conb.2017.09.015 |
0.494 |
|
| 2017 |
Lüders KA, Patzig J, Simons M, Nave KA, Werner HB. Genetic dissection of oligodendroglial and neuronal Plp1 function in a novel mouse model of spastic paraplegia type 2. Glia. PMID 28836307 DOI: 10.1002/Glia.23193 |
0.506 |
|
| 2017 |
Snaidero N, Simons M. The logistics of myelin biogenesis in the central nervous system. Glia. PMID 28168748 DOI: 10.1002/Glia.23116 |
0.56 |
|
| 2017 |
Snaidero N, Velte C, Myllykoski M, Raasakka A, Ignatev A, Werner HB, Erwig MS, Möbius W, Kursula P, Nave KA, Simons M. Antagonistic Functions of MBP and CNP Establish Cytosolic Channels in CNS Myelin. Cell Reports. 18: 314-323. PMID 28076777 DOI: 10.1016/J.Celrep.2016.12.053 |
0.594 |
|
| 2016 |
Romanelli E, Merkler D, Mezydlo A, Weil MT, Weber MS, Nikić I, Potz S, Meinl E, Matznick FE, Kreutzfeldt M, Ghanem A, Conzelmann KK, Metz I, Brück W, Routh M, ... Simons M, et al. Myelinosome formation represents an early stage of oligodendrocyte damage in multiple sclerosis and its animal model. Nature Communications. 7: 13275. PMID 27848954 DOI: 10.1038/Ncomms13275 |
0.465 |
|
| 2016 |
Weil MT, Möbius W, Winkler A, Ruhwedel T, Wrzos C, Romanelli E, Bennett JL, Enz L, Goebels N, Nave KA, Kerschensteiner M, Schaeren-Wiemers N, Stadelmann C, Simons M. Loss of Myelin Basic Protein Function Triggers Myelin Breakdown in Models of Demyelinating Diseases. Cell Reports. PMID 27346352 DOI: 10.1016/J.Celrep.2016.06.008 |
0.558 |
|
| 2016 |
Safaiyan S, Kannaiyan N, Snaidero N, Brioschi S, Biber K, Yona S, Edinger AL, Jung S, Rossner MJ, Simons M. Age-related myelin degradation burdens the clearance function of microglia during aging. Nature Neuroscience. PMID 27294511 DOI: 10.1038/Nn.4325 |
0.485 |
|
| 2016 |
Steshenko O, Andrade DM, Honigmann A, Mueller V, Schneider F, Sezgin E, Hell SW, Simons M, Eggeling C. Reorganization of Lipid Diffusion by Myelin Basic Protein as Revealed by STED Nanoscopy. Biophysical Journal. 110: 2441-50. PMID 27276262 DOI: 10.1016/J.Bpj.2016.04.047 |
0.537 |
|
| 2016 |
Bunk EC, Ertaylan G, Ortega F, Pavlou MA, Gonzalez Cano L, Stergiopoulos A, Safaiyan S, Völs S, van Cann M, Politis PK, Simons M, Berninger B, Del Sol A, Schwamborn JC. Prox1 is required for oligodendrocyte cell identity in adult neural stem cells of the subventricular zone. Stem Cells (Dayton, Ohio). PMID 27068685 DOI: 10.1002/Stem.2374 |
0.341 |
|
| 2016 |
D'Este E, Kamin D, Velte C, Göttfert F, Simons M, Hell SW. Subcortical cytoskeleton periodicity throughout the nervous system. Scientific Reports. 6: 22741. PMID 26947559 DOI: 10.1038/Srep22741 |
0.519 |
|
| 2015 |
Sun X, Bakhti M, Fitzner D, Schnaars M, Kruse N, Coskun Ü, Kremser C, Willecke K, Kappos L, Kuhle J, Simons M. Quantified CSF antibody reactivity against myelin in multiple sclerosis. Annals of Clinical and Translational Neurology. 2: 1116-23. PMID 26734662 DOI: 10.1002/Acn3.264 |
0.305 |
|
| 2015 |
Baskin JM, Wu X, Christiano R, Oh MS, Schauder CM, Gazzerro E, Messa M, Baldassari S, Assereto S, Biancheri R, Zara F, Minetti C, Raimondi A, Simons M, Walther TC, et al. The leukodystrophy protein FAM126A (hyccin) regulates PtdIns(4)P synthesis at the plasma membrane. Nature Cell Biology. PMID 26571211 DOI: 10.1038/Ncb3271 |
0.401 |
|
| 2015 |
Sharma K, Schmitt S, Bergner CG, Tyanova S, Kannaiyan N, Manrique-Hoyos N, Kongi K, Cantuti L, Hanisch UK, Philips MA, Rossner MJ, Mann M, Simons M. Cell type- and brain region-resolved mouse brain proteome. Nature Neuroscience. PMID 26523646 DOI: 10.1038/Nn.4160 |
0.676 |
|
| 2015 |
Nawaz S, Sánchez P, Schmitt S, Snaidero N, Mitkovski M, Velte C, Brückner BR, Alexopoulos I, Czopka T, Jung SY, Rhee JS, Janshoff A, Witke W, Schaap IA, Lyons DA, ... Simons M, et al. Actin Filament Turnover Drives Leading Edge Growth during Myelin Sheath Formation in the Central Nervous System. Developmental Cell. 34: 139-51. PMID 26166299 DOI: 10.1016/J.Devcel.2015.05.013 |
0.461 |
|
| 2015 |
Thumm M, Simons M. Myelinophagy: Schwann cells dine in. The Journal of Cell Biology. 210: 9-10. PMID 26150387 DOI: 10.1083/Jcb.201506039 |
0.441 |
|
| 2015 |
Simons M, Nave KA. Oligodendrocytes: Myelination and Axonal Support. Cold Spring Harbor Perspectives in Biology. PMID 26101081 DOI: 10.1101/Cshperspect.A020479 |
0.575 |
|
| 2015 |
Laulumaa S, Nieminen T, Lehtimäki M, Aggarwal S, Simons M, Koza MM, Vattulainen I, Kursula P, Natali F. Dynamics of the Peripheral Membrane Protein P2 from Human Myelin Measured by Neutron Scattering--A Comparison between Wild-Type Protein and a Hinge Mutant. Plos One. 10: e0128954. PMID 26068118 DOI: 10.1371/Journal.Pone.0128954 |
0.36 |
|
| 2015 |
Kunadt M, Eckermann K, Stuendl A, Gong J, Russo B, Strauss K, Rai S, Kügler S, Falomir Lockhart L, Schwalbe M, Krumova P, Oliveira LM, Bähr M, Möbius W, Levin J, ... ... Simons M, et al. Extracellular vesicle sorting of α-Synuclein is regulated by sumoylation. Acta Neuropathologica. 129: 695-713. PMID 25778619 DOI: 10.1007/S00401-015-1408-1 |
0.313 |
|
| 2015 |
Schmitt S, Cantuti Castelvetri L, Simons M. Metabolism and functions of lipids in myelin. Biochimica Et Biophysica Acta. 1851: 999-1005. PMID 25542507 DOI: 10.1016/J.Bbalip.2014.12.016 |
0.553 |
|
| 2015 |
de Hoz L, Simons M. The emerging functions of oligodendrocytes in regulating neuronal network behaviour. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 37: 60-9. PMID 25363888 DOI: 10.1002/Bies.201400127 |
0.52 |
|
| 2015 |
Nawaz S, Sánchez P, Schmitt S, Snaidero N, Mitkovski M, Velte C, Brückner BR, Alexopoulos I, Czopka T, Jung SY, Rhee JS, Janshoff A, Witke W, Schaap IAT, Lyons DA, ... Simons M, et al. Actin Filament Turnover Drives Leading Edge Growth during Myelin Sheath Formation in the Central Nervous System Developmental Cell. 34: 139-151. DOI: 10.1016/j.devcel.2015.05.013 |
0.332 |
|
| 2014 |
Simons M, Misgeld T, Kerschensteiner M. A unified cell biological perspective on axon-myelin injury. The Journal of Cell Biology. 206: 335-45. PMID 25092654 DOI: 10.1083/Jcb.201404154 |
0.52 |
|
| 2014 |
Snaidero N, Simons M. Myelination at a glance. Journal of Cell Science. 127: 2999-3004. PMID 25024457 DOI: 10.1242/Jcs.151043 |
0.581 |
|
| 2014 |
Snaidero N, Möbius W, Czopka T, Hekking LH, Mathisen C, Verkleij D, Goebbels S, Edgar J, Merkler D, Lyons DA, Nave KA, Simons M. Myelin membrane wrapping of CNS axons by PI(3,4,5)P3-dependent polarized growth at the inner tongue. Cell. 156: 277-90. PMID 24439382 DOI: 10.1016/J.Cell.2013.11.044 |
0.562 |
|
| 2014 |
Ruskamo S, Yadav RP, Sharma S, Lehtimäki M, Laulumaa S, Aggarwal S, Simons M, Bürck J, Ulrich AS, Juffer AH, Kursula I, Kursula P. Atomic resolution view into the structure-function relationships of the human myelin peripheral membrane protein P2. Acta Crystallographica. Section D, Biological Crystallography. 70: 165-76. PMID 24419389 DOI: 10.1107/S1399004713027910 |
0.361 |
|
| 2014 |
Bakhti M, Aggarwal S, Simons M. Myelin architecture: zippering membranes tightly together. Cellular and Molecular Life Sciences : Cmls. 71: 1265-1277. PMID 24165921 DOI: 10.1007/S00018-013-1492-0 |
0.564 |
|
| 2013 |
Ghosh A, Kling T, Snaidero N, Sampaio JL, Shevchenko A, Gras H, Geurten B, Göpfert MC, Schulz JB, Voigt A, Simons M. A global in vivo Drosophila RNAi screen identifies a key role of ceramide phosphoethanolamine for glial ensheathment of axons. Plos Genetics. 9: e1003980. PMID 24348263 DOI: 10.1371/Journal.Pgen.1003980 |
0.478 |
|
| 2013 |
Frühbeis C, Fröhlich D, Kuo WP, Amphornrat J, Thilemann S, Saab AS, Kirchhoff F, Möbius W, Goebbels S, Nave KA, Schneider A, Simons M, Klugmann M, Trotter J, Krämer-Albers EM. Neurotransmitter-triggered transfer of exosomes mediates oligodendrocyte-neuron communication. Plos Biology. 11: e1001604. PMID 23874151 DOI: 10.1371/Journal.Pbio.1001604 |
0.621 |
|
| 2013 |
Aggarwal S, Snaidero N, Pähler G, Frey S, Sánchez P, Zweckstetter M, Janshoff A, Schneider A, Weil MT, Schaap IA, Görlich D, Simons M. Myelin membrane assembly is driven by a phase transition of myelin basic proteins into a cohesive protein meshwork. Plos Biology. 11: e1001577. PMID 23762018 DOI: 10.1371/Journal.Pbio.1001577 |
0.548 |
|
| 2013 |
Simons M, Lyons DA. Axonal selection and myelin sheath generation in the central nervous system. Current Opinion in Cell Biology. 25: 512-9. PMID 23707197 DOI: 10.1016/J.Ceb.2013.04.007 |
0.568 |
|
| 2013 |
Bakhti M, Snaidero N, Schneider D, Aggarwal S, Möbius W, Janshoff A, Eckhardt M, Nave KA, Simons M. Loss of electrostatic cell-surface repulsion mediates myelin membrane adhesion and compaction in the central nervous system. Proceedings of the National Academy of Sciences of the United States of America. 110: 3143-8. PMID 23382229 DOI: 10.1073/Pnas.1220104110 |
0.519 |
|
| 2013 |
Schneider A, Simons M. Exosomes: vesicular carriers for intercellular communication in neurodegenerative disorders. Cell and Tissue Research. 352: 33-47. PMID 22610588 DOI: 10.1007/S00441-012-1428-2 |
0.332 |
|
| 2013 |
Frühbeis C, Fröhlich D, Kuo WP, Amphornrat J, Thilemann S, Saab AS, Kirchhoff F, Möbius W, Goebbels S, Nave K, Schneider A, Simons M, Klugmann M, Trotter J, Krämer-Albers E. Somatodendritic and axonal uptake of exosomes. Plos Biology. DOI: 10.1371/Journal.Pbio.1001604.G007 |
0.437 |
|
| 2012 |
Scheffel J, Regen T, Van Rossum D, Seifert S, Ribes S, Nau R, Parsa R, Harris RA, Boddeke HW, Chuang HN, Pukrop T, Wessels JT, Jürgens T, Merkler D, Brück W, ... ... Simons M, et al. Toll-like receptor activation reveals developmental reorganization and unmasks responder subsets of microglia. Glia. 60: 1930-43. PMID 22911652 DOI: 10.1002/Glia.22409 |
0.351 |
|
| 2012 |
Hagemeyer N, Boretius S, Ott C, Von Streitberg A, Welpinghus H, Sperling S, Frahm J, Simons M, Ghezzi P, Ehrenreich H. Erythropoietin attenuates neurological and histological consequences of toxic demyelination in mice. Molecular Medicine (Cambridge, Mass.). 18: 628-35. PMID 22396019 DOI: 10.2119/Molmed.2011.00457 |
0.396 |
|
| 2012 |
Manrique-Hoyos N, Jürgens T, Grønborg M, Kreutzfeldt M, Schedensack M, Kuhlmann T, Schrick C, Brück W, Urlaub H, Simons M, Merkler D. Late motor decline after accomplished remyelination: impact for progressive multiple sclerosis. Annals of Neurology. 71: 227-44. PMID 22367995 DOI: 10.1002/Ana.22681 |
0.399 |
|
| 2012 |
Simons M, Snaidero N, Aggarwal S. Cell polarity in myelinating glia: from membrane flow to diffusion barriers. Biochimica Et Biophysica Acta. 1821: 1146-53. PMID 22314181 DOI: 10.1016/J.Bbalip.2012.01.011 |
0.44 |
|
| 2011 |
Yurlova L, Kahya N, Aggarwal S, Kaiser HJ, Chiantia S, Bakhti M, Pewzner-Jung Y, Ben-David O, Futerman AH, Brügger B, Simons M. Self-segregation of myelin membrane lipids in model membranes. Biophysical Journal. 101: 2713-20. PMID 22261060 DOI: 10.1016/J.Bpj.2011.10.026 |
0.52 |
|
| 2011 |
Aggarwal S, Yurlova L, Snaidero N, Reetz C, Frey S, Zimmermann J, Pähler G, Janshoff A, Friedrichs J, Müller DJ, Goebel C, Simons M. A size barrier limits protein diffusion at the cell surface to generate lipid-rich myelin-membrane sheets. Developmental Cell. 21: 445-56. PMID 21885353 DOI: 10.1016/J.Devcel.2011.08.001 |
0.541 |
|
| 2011 |
Ghosh A, Manrique-Hoyos N, Voigt A, Schulz JB, Kreutzfeldt M, Merkler D, Simons M. Targeted ablation of oligodendrocytes triggers axonal damage. Plos One. 6: e22735. PMID 21818378 DOI: 10.1371/Journal.Pone.0022735 |
0.458 |
|
| 2011 |
Aggarwal S, Yurlova L, Simons M. Central nervous system myelin: structure, synthesis and assembly. Trends in Cell Biology. 21: 585-93. PMID 21763137 DOI: 10.1016/J.Tcb.2011.06.004 |
0.582 |
|
| 2011 |
Fitzner D, Schnaars M, van Rossum D, Krishnamoorthy G, Dibaj P, Bakhti M, Regen T, Hanisch UK, Simons M. Selective transfer of exosomes from oligodendrocytes to microglia by macropinocytosis. Journal of Cell Science. 124: 447-58. PMID 21242314 DOI: 10.1242/Jcs.074088 |
0.416 |
|
| 2011 |
Bakhti M, Winter C, Simons M. Inhibition of myelin membrane sheath formation by oligodendrocyte-derived exosome-like vesicles. The Journal of Biological Chemistry. 286: 787-96. PMID 20978131 DOI: 10.1074/Jbc.M110.190009 |
0.564 |
|
| 2010 |
Strauss K, Goebel C, Runz H, Möbius W, Weiss S, Feussner I, Simons M, Schneider A. Exosome secretion ameliorates lysosomal storage of cholesterol in Niemann-Pick type C disease. The Journal of Biological Chemistry. 285: 26279-88. PMID 20554533 DOI: 10.1074/Jbc.M110.134775 |
0.303 |
|
| 2010 |
Hsu C, Morohashi Y, Yoshimura S, Manrique-Hoyos N, Jung S, Lauterbach MA, Bakhti M, Grønborg M, Möbius W, Rhee J, Barr FA, Simons M. Regulation of exosome secretion by Rab35 and its GTPase-activating proteins TBC1D10A-C. The Journal of Cell Biology. 189: 223-32. PMID 20404108 DOI: 10.1083/Jcb.200911018 |
0.371 |
|
| 2010 |
Saher G, Simons M. Cholesterol and myelin biogenesis. Sub-Cellular Biochemistry. 51: 489-508. PMID 20213556 DOI: 10.1007/978-90-481-8622-8_18 |
0.57 |
|
| 2009 |
Kippert A, Fitzner D, Helenius J, Simons M. Actomyosin contractility controls cell surface area of oligodendrocytes. Bmc Cell Biology. 10: 71. PMID 19781079 DOI: 10.1186/1471-2121-10-71 |
0.511 |
|
| 2009 |
Simons M, Raposo G. Exosomes--vesicular carriers for intercellular communication. Current Opinion in Cell Biology. 21: 575-81. PMID 19442504 DOI: 10.1016/J.Ceb.2009.03.007 |
0.318 |
|
| 2009 |
Nawaz S, Kippert A, Saab AS, Werner HB, Lang T, Nave KA, Simons M. Phosphatidylinositol 4,5-bisphosphate-dependent interaction of myelin basic protein with the plasma membrane in oligodendroglial cells and its rapid perturbation by elevated calcium. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 4794-807. PMID 19369548 DOI: 10.1523/Jneurosci.3955-08.2009 |
0.476 |
|
| 2008 |
Kippert A, Trajkovic K, Fitzner D, Opitz L, Simons M. Identification of Tmem10/Opalin as a novel marker for oligodendrocytes using gene expression profiling. Bmc Neuroscience. 9: 40. PMID 18439243 DOI: 10.1186/1471-2202-9-40 |
0.569 |
|
| 2008 |
Schneider A, Rajendran L, Honsho M, Gralle M, Donnert G, Wouters F, Hell SW, Simons M. Flotillin-dependent clustering of the amyloid precursor protein regulates its endocytosis and amyloidogenic processing in neurons Journal of Neuroscience. 28: 2874-2882. PMID 18337418 DOI: 10.1523/Jneurosci.5345-07.2008 |
0.316 |
|
| 2008 |
Trajkovic K, Hsu C, Chiantia S, Rajendran L, Wenzel D, Wieland F, Schwille P, Brügger B, Simons M. Ceramide triggers budding of exosome vesicles into multivesicular endosomes Science. 319: 1244-1247. PMID 18309083 DOI: 10.1126/Science.1153124 |
0.311 |
|
| 2007 |
Simons M, Trotter J. Wrapping it up: the cell biology of myelination. Current Opinion in Neurobiology. 17: 533-40. PMID 17923405 DOI: 10.1016/J.Conb.2007.08.003 |
0.696 |
|
| 2007 |
Kippert A, Trajkovic K, Rajendran L, Ries J, Simons M. Rho regulates membrane transport in the endocytic pathway to control plasma membrane specialization in oligodendroglial cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 3560-70. PMID 17392472 DOI: 10.1523/Jneurosci.4926-06.2007 |
0.363 |
|
| 2007 |
Simons M. Mechanisms of myelin membrane biogenesis Gbm Annual Spring Meeting Mosbach 2007. 2007. DOI: 10.1240/SAV_GBM_2007_M_001809 |
0.369 |
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| 2006 |
Simons M, Trajkovic K. Neuron-glia communication in the control of oligodendrocyte function and myelin biogenesis. Journal of Cell Science. 119: 4381-9. PMID 17074832 DOI: 10.1242/Jcs.03242 |
0.472 |
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| 2006 |
Fitzner D, Schneider A, Kippert A, Möbius W, Willig KI, Hell SW, Bunt G, Gaus K, Simons M. Myelin basic protein-dependent plasma membrane reorganization in the formation of myelin. The Embo Journal. 25: 5037-48. PMID 17036049 DOI: 10.1038/Sj.Emboj.7601376 |
0.508 |
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| 2006 |
Trajkovic K, Dhaunchak AS, Goncalves JT, Wenzel D, Schneider A, Bunt G, Nave KA, Simons M. Neuron to glia signaling triggers myelin membrane exocytosis from endosomal storage sites. The Journal of Cell Biology. 172: 937-48. PMID 16520383 DOI: 10.1083/Jcb.200509022 |
0.515 |
|
| 2005 |
Schneider A, Länder H, Schulz G, Wolburg H, Nave KA, Schulz JB, Simons M. Palmitoylation is a sorting determinant for transport to the myelin membrane. Journal of Cell Science. 118: 2415-23. PMID 15923654 DOI: 10.1242/Jcs.02365 |
0.516 |
|
| 2004 |
Schneider A, Araújo GW, Trajkovic K, Herrmann MM, Merkler D, Mandelkow EM, Weissert R, Simons M. Hyperphosphorylation and aggregation of tau in experimental autoimmune encephalomyelitis. The Journal of Biological Chemistry. 279: 55833-9. PMID 15494405 DOI: 10.1074/Jbc.M409954200 |
0.439 |
|
| 2002 |
Simons M, Schwärzler F, Lütjohann D, von Bergmann K, Beyreuther K, Dichgans J, Wormstall H, Hartmann T, Schulz JB. Treatment with simvastatin in normocholesterolemic patients with Alzheimer's disease: A 26-week randomized, placebo-controlled, double-blind trial. Annals of Neurology. 52: 346-50. PMID 12205648 DOI: 10.1002/Ana.10292 |
0.347 |
|
| 2002 |
Simons M, Kramer EM, Macchi P, Rathke-Hartlieb S, Trotter J, Nave KA, Schulz JB. Overexpression of the myelin proteolipid protein leads to accumulation of cholesterol and proteolipid protein in endosomes/lysosomes: implications for Pelizaeus-Merzbacher disease. The Journal of Cell Biology. 157: 327-36. PMID 11956232 DOI: 10.1083/jcb.200110138 |
0.561 |
|
| 2000 |
Simons M, Krämer EM, Thiele C, Stoffel W, Trotter J. Assembly of myelin by association of proteolipid protein with cholesterol- and galactosylceramide-rich membrane domains. The Journal of Cell Biology. 151: 143-54. PMID 11018060 DOI: 10.1083/Jcb.151.1.143 |
0.625 |
|
| 1998 |
Simons M, Keller P, De Strooper B, Beyreuther K, Dotti CG, Simons K. Cholesterol depletion inhibits the generation of beta-amyloid in hippocampal neurons. Proceedings of the National Academy of Sciences of the United States of America. 95: 6460-4. PMID 9600988 DOI: 10.1073/Pnas.95.11.6460 |
0.471 |
|
| 1997 |
Tienari PJ, Ida N, Ikonen E, Simons M, Weidemann A, Multhaup G, Masters CL, Dotti CG, Beyreuther K. Intracellular and secreted Alzheimer beta-amyloid species are generated by distinct mechanisms in cultured hippocampal neurons. Proceedings of the National Academy of Sciences of the United States of America. 94: 4125-30. PMID 9108116 DOI: 10.1073/Pnas.94.8.4125 |
0.442 |
|
| 1996 |
De Strooper B, Moechars D, Tienari P, Simons M, Beyreuther K, Dotti C, Van Leuven F. 174 Processing of APP in polarized epithelial cells and neurons: relationships among cell types Neurobiology of Aging. 17: S44-S45. DOI: 10.1016/S0197-4580(96)80176-X |
0.381 |
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